Publications





Journal Publications  
 
*:Corresponding Author; +: Equal Contribution   
  
22. Zhen Gu... in preparation, 2012.
 
21. Zhen Gu, Alex Aimetti, Qun Wang, Tram T. Dang, Yunlong Zhang, Omid Veiseh, Hao Cheng, Robert Langer, Daniel G. Anderson, in preparation, 2012.
 
20. Zhen Gu, Tram T. Dang, Benjamin C. Tang, Hao Cheng, Shan Jiang, Yizhou Dong, Yunlong Zhang, Daniel G. Anderson, in preparation, 2012.
 
19. Muxun Zhao, Biliang Hu, Zhen Gu, Kye-ll Joo, Pin Wang, Yi Tang, submitted, 2012.
  
18. Zhen Gu,...Journal of Controlled Release, invited manuscript, 2012.
 
17. Zhen Gu*, Anuradha Biswas, Muxun Zha, Yi Tang*, "Tailoring Nanocarriers for Intracellular Protein Delivery" Chemical Society Reviews, 40(3638), 2011. (corresponding author, invited manuscript) 
 
16. Muxun Zhao, Anuradha Biswas, Biliang Hu, Kye-Il Joo, Pin Wang, Zhen Gu*, Yi Tang*, "Redox-Responsive Nanocapsules for Intracellular Protein Delivery" Biomaterials, 32(5223), 2011. (co-corresponding author) 
  
 
15. Kye-Il Joo, Yun Fang, Yarong Liu, Liang Xiao, Zhen Gu, April Tai, Chi-Lin Lee, Yi Tang, Pin Wang*,"Enhanced Real-Time Monitoring of Adeno-Associated Virus Trafficking by Virus-Quantum Dot Conjugates" ACS Nano, 5(3523), 2011.
 
14. Zhen Gu*, Muxun Zhao, Yuewei Sheng, Laurent A. Bentolila, Yi Tang*, "Detection of Mercury Ion by Infrared Fluorescent Protein and Its Hydrogel-Based Paper Assay" Analytical Chemistry, 83(2324), 2011. (co-corresponding author) 
 
 
13. Anuradha Biswas , Kye-Il Joo, Jing Liu , Muxun Zhao , Guoping Fan , Pin Wang , Zhen Gu* , Yi Tang*, "Endoprotease-Mediated Intracellular Protein Delivery Using Nanocapsules" ACS Nano, 5 (1385)2011. (co-corresponding author) 
 
 
 
12. Bin Sun, Min-Jie Sun,  Zhen Gu, Qun-Dong Shen*, Shao-Jun Jiang, Yu Wang, "Conjugated Polymer Fluorescence Probe for Intracellular Imaging of Magnetic Nanoparticles" Macromolecules, 43 (10348), 2010.
  
 
11. Zhen Gu, Anuradha Biswas, Kye-Il Joo, Biliang Hu, Pin Wang,  Yi Tang*, "Probing Protease Activity by Single-Fluorescent-Protein Nanocapsules" Chemical Communications, 46 (6467), 2010.
 

 
 
10. Zhen Gu* and Yi Tang*, "Enzyme-Assisted Photolithography for Spatial Functionalization of Hydrogels" Lab on a Chip, 10 (1946), 2010.(Highlighted as a Front Cover, co-corresponding author) 
 
9. Zhen GuXiao-Yuan Chen, Qun-Dong Shen, Hai-Xiong Ge, Hai-Hua Xu, "Hybrid Nanocomposites of Semiconductor Nanoparticles and Conjugated Polyelectrolytes and Their Application as Fluorescence Biosensors" Polymer, 51 (902), 2010.
 
 
 

8. Ming Yan+, Juanjuan Du+, Zhen Gu, Min Liang, Yufang Hu, Wenjun Zhang, Tatiana Segura, Zheng Liu, Yi Tang*, Yunfeng Lu*, “A Novel Intracellular Protein Delivery Platform Based on Single-Protein Nanocapsules” Nature Nanotechnology, 5(48), 2010. (Highlighted in Science Daily)

 
7. Zhen Gu, Ming Yan, Biliang Hu, Kye-Il Joo, Anuradha Biswas, Yu Huang, Yunfeng Lu*, Pin Wang* and Yi Tang*, "Protein Nanocapsule Weaved with Enzymatically Degradable Polymeric Network" Nano Letters, 12(4533), 2009. (Featured in Journal of World News and the homepage of Nano Letters)
 
 
6. Zhen Gu*, Suxian Huang, Yong Chen*, “Biomolecular Nanopatterning by Magnetic Electric Lithography” Angewandte Chemie International Edition, 48(952), 2009. (Highlighted as a Front Cover, corresponding author)
 
5. Lei Zhang, Zhen Gu, Zhiping Yu, Xiangqing He, and Yong Chen. “A CMOS Microarray with On-chip Decoder/Amplifier and Its Integration with Bio-Nano-System” Journal of Semiconductors, 29(10) (1947), 2008.
 

 

4. Qianxi Lai, Zhiyong Li, Lei Zhang, Xuema Li, William F. Stickle, Zuhua Zhu, Zhen Gu, Theodore I. Kamins, R. Stanley Williams, and Yong Chen* “An Organic/Si Nanowire Hybrid Field Configurable Transistor”, Nano Letters, 3 (876), 2008.

 

 
 

3. Zhen Gu, Qun-Dong Shen*, Yang Zhang, “Distinct Photophysical Properties of an Anionic Water-Soluble Poly(Phenylene Vinylene) Alternating Copolymer”, Polymer Division of Chinese Chemical Society 2005 Annual Conference.

 

 

2. Zhen Gu, Yong-Jun Bao, Yang Zhang, Mu Wang, Qun-Dong Shen*, “Enhanced Photoluminescence and Dual Electroluminescence of Anionic Water-Soluble Poly(Phenylene Vinylene) Alternating Copolymer”, Macromolecules, 39 (3125), 2006.

 
 

1. Zhen Gu, Qun-Dong Shen*, Juan Zhang, Chang-Zheng Yang, “Dual Electroluminescence from a Single-Component Light-emitting Electrochemical Cell Based on Water-Soluble Conjugated Polymer”, Journal of Applied Polymer Science, 100 (2930), 2006

 

 

Book Chapters

1. Zhen Gu*, Yi Tang, Yong Chen. "Fabrication of Biomolecular Nanopatterns" In: F.Columbus "Advances in Nanotechnology". Nova Science Publishers, 2010. (Invited Review; Corresponding Author)

 Advances in Nanotechnology. Volume 1

 
Inventions
 

1. Zhen Gu, Alex Aimetti, Daniel Anderson, Robert Langer, “A Glucose-Mediated Delivery System for Diabetes Treatment” MIT Technology Disclosure, Case#-15469, 2012.

 

2. Zhen Gu, Daniel Anderson, Robert Langer, “Micro-Device for Glucose-Responsive Delivery of Insulin” MIT Case#-15056, U.S. Application Serial No. 61/476,094, filed 02/17/2012.

 

3. Zhen Gu, Alex Aimetti, Daniel Anderson, Robert Langer, “Self-assembled System for Intelligent Insulin Delivery” MIT Case#-15057, U.S. Application Serial No. 61/476,094, filed 02/17/2012.

 

4. Yi Tang, Zhen Gu, Yunfeng Lu, Ming Yan, Anuradha Biswas, Guoping Fan. “Protease-Assisted Native-Protein Delivery Approach” UC.-Case#-531. U.S. Patent Application Serial No. 13/089,117, filed 04/18/2011.

 

5. Yi Tang, Zhen Gu, Muxun Zhao. “Redox Responsive Nanocapsules for Protein Delivery” UC.-Case#-659. U.S. Application Serial No. 61/476,094, filed 04/15/2011.

 

6.Yi Tang, Zhen Gu,  Yunfeng Lu, Ming Yan. “Protease-Assisted Photolithography” UC.-Case#-086, 2010. 

 

7. Yi Tang, Zhen Gu, “Photo/Enzyme Synergistically Responsive Matrix” UC.-Case#-246, 2010. 

 

8. Yi Tang, Zhen Gu, Anuradha Biswas, Guoping Fan. “Endoprotease-Mediated Protein Intracellular Delivery” UC.-Case#-014, 2010. 

 

9. Yi Tang, Zhen Gu, “Protein/Hydrogel Based Paper Assay” UC.-Case#-211, 2010.

 

10. Qun-Dong Shen, Bin Sun, Yang Zhang, Zhen Gu.  “Preparation and Application of a Magnetic/Fluorescent Hybrid Nanocompsite Material” China Patent No. 200810020415, filed 08/06/2008. 


 
 Conference Presentations
 
18. Zhen Gu, "Delivering and Positioning Protein Using Novel Hydrogel Based Platforms" Special Seminar in Nanjing University, Sep. 16, 2011, Nanjing, Jiangsu, China. (Invited Talk)
 
17. Anuradha Biswas, Zhen Gu,  Muxun Zhao, Yi Tang, "Endoprotease-mediated Intracellular protein delivery" Society of Biomaterials, 2011 Annual Meeting, Apr. 13-16, 2011, Orlando, FL, USA. (Oral Presentation)

 

16. Anuradha Biswas, Zhen Gu,  Muxun Zhao, Yi Tang, "Endoprotease-mediated Intracellular protein delivery" 241th ACS National Meeting, Mar. 27-31, 2011, Anaheim, CA, USA. (Poster)

 
15. Muxun Zhao, Anuradha Biswas, Zhen Gu, Yi Tang, "Delivery of Protein Nanocapsules to Cancer Cells", AACR Special Conference: Nano In Cancer, 2011, Miami, FL, USA. (Poster)
 
14. Anuradha Biswas, Zhen Gu,  Muxun Zhao, Yi Tang, "Development of a Proteolytically Triggered Intracellular Protein Delivery System" 2010 AICHE Annual, USA. (Oral Presentation)
 
13. Zhen Gu, Yi Tang, "At the Interface of Bio and Nano" Nagoya University-UCLA Annual Forum2010. (Invited Talk)
 
12. Zhen Gu, Anuradha Biswas, Muxun Zhao, Yi Tang, "Cocoon-like Protease-Assisted Native-protein Delivery Approach (PANDA)" 2010 UCLA Engineering Tech Forum, Los Angeles, CA, USA. (Poster)
 
11. Juanjuan Du, Ming Yan, Zhen Gu, Titiana Segura, Yi Tang, Yunfeng Lu,  2010 MRS Spring Meeting, San Francisco, CA, USA. (Oral Presentation)
 
10.  Ming Yan, Juanjuan Du, Zhen Gu, Yi Tang, Yunfeng Lu,  2010 MRS Spring Meeting, San Francisco, CA, USA. (Oral Presentation)
 
9. Zhen Gu, Anuradha Biswas, Ming Yan, Pin Wang, Yunfeng Lu, Yi Tang, "Photo/Enzyme Synergistically Responsive Gel Matrix" 2010 MRS Spring Meeting, San Francisco, CA, USA. (Oral Presentation)
 
8.Juanjuan Du,  Qi Zhu, Ming Yan, Zhen Gu, Yi Tang, Yunfeng Lu, "Biosensors for organophosphate based on single enzyme nanocapsules" Chemical and Biological Defense Science and Technology (CBD S&T) Conference, Dallas, TX, USA, 2009. (Poster)

 

7. Ming Yan, Juanjuan Du, Qi Zhu, Zhen Gu, Yunfeng Lu, Yi Tang, "Design of Highly Robust Single Enzyme Biocatalysts" Chemical and Biological Defense Science and Technology (CBD S&T) Conference, Dallas, TX, USA, 2009. (Oral Presentation)

 

6.Yunfeng Lu, Ming Yan, Juanjuan Du, Qi Zhu, Zhen Gu, Yi Tang, "A Novel Intracellular Protein Delivery Platform" Chemical and Biological Defense Science and Technology (CBD S&T) Conference, Dallas, TX, USA, 2009. (Oral Presentation)

 

5. Zhen Gu, Ming Yan, Juanjuan Du, Yunfeng Lu, Tatiana Segura, Yi Tang "Enzyme-Responsible Single Protein Encapsulated Nanogels for Intracellular Delivery" 2009 MRS Spring Meeting, San Francisco, CA, USA, 2009. (Oral Presentation)

 

4. Zhen Gu, Lei Zhang*, Zhiping Yu, Xiangqing He, Yong Chen, "Dynamic Bio-Nano System on a CMOS Microarray by Magnetic Electric Patterning" 2009 MRS Spring Meeting, San Francisco, CA, USA, 2009. (Poster)

 

3. Zhen Gu, Suxian Huang, Yong Chen, “Magnetic Biomolecular Nanopatterning by Magnetic Electric Lithography” The 5th FCRP FENA Annual Review, Los Angeles, CA, 2009. (Poster)

 

2. Qianxi Lai, Lei Zhang, Zhen Gu, et al. “Ionic-doping Based Configurable Electronic Devices-Organic Nonvolatile Memory and Field- Configurable Transistor” California NanoSystems Institute (CNSI) Conference and Grand Opening, Los Angeles, CA, USA, Dec. 14, 2007. (Poster)

 

1. Zhen Gu, Qun-Dong Shen, Yang Zhang, “Distinct Photophysical Properties of an Anionic Water-Soluble Poly(Phenylene Vinylene) Alternating Copolymer”, Polymer Division of Chinese Chemical Society Annual Conference. 2005, Beijing, China. (Oral Presentation)

 

 

 

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