Barrx™ Radio Frequency Ablation
Press Release by American Gastroenterology Society
Watchful waiting no longer recommended for some high-risk Barrett’s esophagus patients
The Barrx RFA treatment
Barrx RFA treatment is applied during an endoscopy procedure (a
camera test of the gullet) to destroy the abnormal Barrett’s oesophagus
lining. The lining which regrows is usually normal.
There are two different types of Barrx RFA device. The Barrx 360
device treats the entire wall of the gullet. The Barrx 90 device is
similar, but treats a smaller area.
Patients are usually treated with the Barrx 360 device initially and
if, at the next endoscopy, there is any abnormal Barrett’s oesophagus
lining left, retreatment with either the Barrx 360 or Barrx 90 device,
depending on how big the area needing treatment is.
How The Barrx RFA System Treats Barrett's Oesophagus
Circumferential Radio Frequency Ablation
There are two types of procedure using the Barrx RFA System:
During the Procedure
Using standard endoscopy techniques, the physician activates and controls the different functions of the Barrx 360 System.
- A catheter is inserted into the Oesophagus along side the endoscope
- At the tip of the catheter there is a small balloon that is inflated
once inside your Oesophagus near the treatment area. The balloon and
the Barrx Energy Generator together measure the diameter of the
Oesophagus. This information is used by the physician to select the
appropriate treatment catheter.
- The sizing balloon is then removed and the treatment and the Barrx 360+ Ablation Catheter is introduced.
- The Barrx 360+ Ablation Catheter also has a balloon at the tip,
but this balloon is covered by a band of radio frequency electrodes.
the electrodes of the balloon are positioned on the desired treatment
area the balloon is inflated. The Barrx 360 Energy Generator and the
ablation catheter then work together to deliver a short burst of energy
that is circumferential: 360 degrees. Once the electrodes of the balloon
are positioned on the desired treatment area the balloon is inflated.
The Barrx 360 Energy Generator and the ablation catheter then work
together to deliver a short burst of energy that is circumferential: 360
- The design of this technology limits the
energy delivery to a depth clinically proven to remove the diseased
tissue while reducing the risk of injury to the deeper and healthy
- The Barrx 360+ Ablation Catheter ablates a 3cm circumferential segment of Barrett's tissue within the oesophagus
- For patients with Barrett's Oesophagus lesions longer than 3cm, the
Barrx 360+ Ablation Catheter is simply repositioned and the ablation
steps are repeated.
What to Expect After the Procedure
It is very important that a patient follows the discharge instructions
provided by the physician or the nursing staff after the procedure to
ensure limited time of discomfort and ensure proper healing of the
Oesophagus. Clinical studies show that re-growth of healthy tissue
occurs within one month in the treated area.
The studies also demonstrated that patients had 90% of their
Barrett's removed after one or two treatment sessions at one year
follow-up. In addition the studies showed that over 70% of the patients
were completely cured of their Barrett's after 1 or 2 treatments at one
year follow-up. The remaining patients had small focal areas left to be
A follow-up appointment will be scheduled by the physician's office
to conduct an upper endoscopy to inspect the treated area determine if
an additional treatment is necessary.
Focal Radio Frequency Ablation
During The Procedure
Using standard endoscopy techniques, the physician activates and controls the different functions of the Barrx 90 System.
- The ablation catheter is first mounted onto the endoscope.
- Both devices are introduced into the oesophagus.
- By manipulating the endoscope, the ablation catheter is positioned
within the Oesophagus at the affected portion of the oesophagus.
- The physician delivers ablative energy to the targeted tissue. The
energy application is less than 1 second and is delivered in an
automated manner. The design of this technology limits the energy
delivery to a depth clinically shown to remove the diseased tissue (less
than 1mm) while reducing the risk of injury to the deeper tissue
- For patients with more than one lesion of Barrett's Oesophagus, the Barrx 90 Ablation Catheter is repositioned and the ablation steps are
Interview with Grant Fullerton (video)
Where to get Barrx™ RFA Treatment?
For more information on the Barrx RFA System visit http://www.curebarretts.com/
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