Research Programs


Resistance Nodulation Division (RND) multidrug efflux pumps in Acinetobacter baumannii

This program aims to characterize RND pumps in A. baumannii, establish their substrate profiles, decipher their regulatory pathways, and investigate their role in the antibiotic resistance as well as virulence. The ultimate long-term goal of this program is to identify inhibitors of A. baumannii RND pumps.

Molecular mechanisms of assembly of RND efflux pumps of Pseudomonas aeruginosa

This program investigates the assembly of RND pump complexes in Pseudomonas aeruginosa. Elucidating the mechanisms of interactions involving different components of RND pumps will help to design new therapy that can inhibit the action of these pumps by interfering with the assembly of different components.

Studying microbiological quality of drinking water from Manitoba First Nations

Specific goal of this program is to investigate the prevalence antibiotic resistant bacteria in source and drinking water from First Nations communities in Manitoba.

Further, we are a member of the Manitoba Chemosensory Biology Research Group (MCSB). Our involvement with this group entails studying bacterial chemosensation including research on bacterial biofilms, quorum sensing, and bacteria-host cell communications with a specific focus on Cystic Fibrosis disease.