Associative Learning: Cerebellar Classical Conditioning
Thinking in Time: Cognition, Communication & Learning (CCL)
Dept of Experimental Medical Science,
S-221 84, Lund
Phone: +46 709 746609
Other profiles: Blog, Google Scholar, Facebook, Google+, Researcher ID, ResearchGate, Orcid
Associates: Research Environment (CCL), Research Group, Germund Hesslow, Dan-Anders Jirenhed
I am researcher in Psychology and Neuroscience. I am currently investigating the role of the mGluR7 receptor in various forms of learning in Chris De Zeeuw's lab at Erasmus MC in the Netherlands.
The aim of my PhD project, supervised by Professor Germund Hesslow
, was to examine the feedback mechanisms that regulate learning during Pavlovian eyeblink conditioning. My colleague, Dan-Anders Jirenhed had previously shown that plastic changes in Purkinje cells, in the cerebellar cortex, play a critical role in this type of learning. In my Ph.D. thesis, I show that the same plastic changes that generate the learned response also influence the input that give rise to the learning in the first place. My postdoctoral project, financed by the Swedish Research Council and EMBO, was inspired by Fredrik Johansson's research showing that blocking the mGluR7 receptor abolished previously learned cellular responses in the Purkinje cell that we believe drives the behavior. Using global and Purkinje cell specific knockouts, as well as pharmacological methods, I will narrow in on what function the mGluR7 receptors plays in behavior
Curriculum Vitae, Anders Rasmussen, PhD, BSc
Anders Rasmussen, PhD, BSc
Phone: +46 709 746609
Sep 2015 - Present: Post-doctoral fellow. Erasmus MC, Netherlands
Jun 2014 - Aug 2015: Assistant researcher in Neurophysiology. Professor Germund Hesslow’s lab, Lund University. Studying associative learning in humans
Feb 2008 - Jun 2014: PhD student. Professor Germund Hesslow’s lab, Lund University. Studying cellular mechanisms and feedback systems involved in associative learning
Sep 2007- Dec 2007: Project assistant. Professor Mikael Johansson’s lab, Lund University. Studying EEG activity related to stereotypes and category norms in language
Apr 2006 - Jun 2006: Undergraduate assistant. Researcher Osnat Ben-Shahar’s lab, University of California, Santa Barbara. Studying operant conditioning and neuropharmacology
Oct 2005 - Jun 2006: Undergraduate assistant. Professor Barry Giesbrecht, University of California, Santa Barbara. Studying EEG activity and attention,
2004 - 2005: Undergraduate assistant. Associate Professor Jean-Christophe Rohner’s lab, Lund University. Studying the physical attractiveness stereotype and memory biases
Peer reviewed articles
Zucca R, Rasmussen A, Bengtsson F (2016) Climbing Fiber Regulation of Spontaneous Purkinje Cell Activity and Cerebellum-Dependent Blink Responses. eNeuro
Rasmussen A, Zucca R, Johansson F, Jirenhed D, Hesslow G (2015) Purkinje cell activity during classical conditioning with different conditional stimuli explains central tenet of Rescorla-Wagner model. Proc Natl Acad Sci USA.
Johansson F, Carlsson HAE, Rasmussen A, Yeo CH, Hesslow G (2015) Activation of a Temporal Memory in Purkinje Cells by the mGluR7 Receptor. Cell Rep 13:1741–1746.
Johansson, F., Jirenhed, D., Rasmussen, A., Zucca, R., & Hesslow, G. (2014). Memory trace and timing mechanism localized to cerebellar Purkinje cells. Proc Natl Acad Sci U S A, 111(41), 14930–14934.
Rasmussen, A., Jirenhed, D., Wetmore, D. Z., & Hesslow, G. (2014). Changes in complex spike activity during classical conditioning. Front Neural Circuits, 8.
Rasmussen, A., & Hesslow, G. (2014). Feedback control of learning by the cerebello-olivary pathway. Prog Brain Res, 210, 103–119.
Wetmore, D. Z., Jirenhed, D., Rasmussen, A., Johansson, F., Schnitzer, M. J., & Hesslow, G. (2014). Bidirectional plasticity of Purkinje cells matches temporal features of learning. Journal of Neuroscience, 1731–1737.
Rasmussen, A., Zucca, R., Jirenhed, D., Johansson, F., Örtenblad, C., Svensson, P., & Hesslow, G. (2013). Golgi Cell Activity During Eyeblink Conditioning in Decerebrate Ferrets. Cerebellum (London, England).
Rasmussen, A., Jirenhed, D., Zucca, R., Johansson, F., Svensson, P., & Hesslow, G. (2013). Number of spikes in climbing fibers determines the direction of cerebellar learning. Journal of Neuroscience, 33(33), 13436–13440.
Hesslow, G., Jirenhed, D., Rasmussen, A., & Johansson, F. (2013). Classical conditioning of motor responses: what is the learning mechanism? Neural Netw.
Hellerstedt, R., Rasmussen, A., & Johansson, M. (2012). Swedish Category Norms. (M. Lindgren, Ed.). Lund Psychological Reports, 12.
Rohner, J.-C., & Rasmussen, A. (2012). Recognition bias and the physical attractiveness stereotype. Scandinavian journal of psychology, 53(3), 239–246.
Rohner, J.-C., & Rasmussen, A. (2011). Physical attractiveness stereotype and memory. Scandinavian journal of psychology.
Rasmussen, A., Jirenhed, D., & Hesslow, G. (2008). Simple and complex spike firing patterns in Purkinje cells during classical conditioning. Cerebellum (London, England), 7(4), 563–566.
Rohner, J.-C., & Rasmussen, A. (2007). Physical attractiveness stereotype and memory. (S.-B. Hansson & M. Lindgren, Eds.) Lund Psychological Reports, 8.
Rasmussen, A., Zucca, R., Johansson, F., Jirenhed, D. & Hesslow, G. (2015). Learning induced pause responses in Purkinje cells reduce the probability that a subsequent periorbital stimulus elicits a complex spike. Meeting for the Society for Research on the Cerebellum (SRC)
Rasmussen, A., Zucca, R., Jirenhed, D., Johansson, F., & Hesslow, G. (2013). Direction of learning in cerebellar Purkinje cells dependent on number of climbing fiber impulses.Translational Sensorimotor Neuroscience Meeting.
Zucca, R., Rasmussen, A., Johansson, F., Verschure, P. F., & Hesslow, G. (2012). Suppression of conditioned eye-blink responses through high frequency climbing fibres stimulation. Federation of European Neuroscience Societies. Barcelona.
Rasmussen, A., Zucca, R., Jirenhed, D., Johansson, F., Örtenblad, C., Svensson, P., & Hesslow, G. (2012). Golgi Cell Activity during Eyeblink Conditioning in Decerebrate Ferrets. Society For Neuroscience. New Orleans.
Johansson, F., Jirenhed, D., Rasmussen, A., Zucca, R., & Hesslow, G. (2011). In vivo parallel fibre stimulation as conditional stimulus in Pavlovian conditioning of Purkinje neuron responses. Society For Neuroscience. Washington DC.
Rasmussen, A., Johansson, F., Zucca, R., & Hesslow, G. (2011). The neural foundation of overexpectation. Society For Neuroscience. Washington DC.
Zucca, R., Rasmussen, A., Herreros-Alonso, I., Verschure, P. F., & Hesslow, G. (2010). A closed-loop framework to investigate cerebellar learning in a decerebrated ferret preparation. Society For Neuroscience. San Diego.
Rasmussen, A., Jirenhed, D., & Hesslow, G. (2008). Olivary activity during Classical Conditioning. Motor Networks. Lund.
Rasmussen, A. (2006, December 18). Electrophysiology of stereotypes: N400 as a measure of the beautiful is good stereotype. (M. Johansson, Ed.). Lund University.
Awards and funding
Jun 2016 - Swedish Research Council, International Post-doc grant
Jun 2016 - EMBO long term fellowship award
May 2015 - Masao Ito prize for best poster presentation at the meeting for the Society for Research on the Cerebellum (SRC), in Brussels
Commissions of trust
Nov 2016 - Half-time opponent for Jonas Enander, PhD candidate, Lund University
Mar 2016 - External examiner on PhD thesis defense for Jochen Spanke, Erasmus MC
Okt 2016 - Neuroscience letters
Dec 2014 - Frontiers in Neuroscience
Mar 2014 - Journal of Social Psychology
Teaching and Supervisory Experience
Okt 2014 - Present: Assistant supervisor for PhD candidate
Jan 2014 - Present: Co-Supervisor for international exchange students, on Bachelor, Master and PhD levels
Jun 2011 - Aug 2011: Supervisor for summer student
2008 - Present: Lund Medical School, Lab supervisor
Jan 2008 - Present: Lund Medical School, PBL tutor
Jul 2016 - FENS, Federation of European Neuroscience Societies, 5 day meeting, Copenhagen, Denmark
Jun 2016 - Kavli futures symposium, 2 day symposium, Santa Barbara, California, USA
Spring 2015 - SRC (Society for Research on the Cerebellum), 2 day symposium. Brussels, Belgium, Poster + Oral presentation
Spring 2013 - Translational Sensorimotor Neuroscience meeting. Johannesbergs Slott, Sweden. Participation + Poster presentation + oral presentation
Annually 2008-2013 - Neuroscience day, Participation + 2 poster presentations
Fall 2011: Meeting for the Society for Neuroscience, Washington DC, USA. Participation + Poster presentation
Spring 2011 - Organization and Function of Neuronal Circuits in Movement Control, 2 day symposium. Trolleholm, Sweden
Spring 2008 - SRC (Society for Research on the Cerebellum), 2 day symposium. Geneva, Switzerland, Participation
Fall 2008 - Motor Networks, 1 day conference, Lund, Sweden. Participation + Poster presentation
Fall 2008 - Perceptual Learning, Motor Learning and Automaticity, 4 day symposium, Amsterdam, Netherlands, Participation + Poster presentation
Wrote an evaluation of the education of the medical program in Lund and discussed the
PhD in Medical Science, Lund University, Sweden
Introductory meeting 1p
Scientific communication 1,5p
Research ethics 1,5p
Oral communication, 1,5p
Laboratory Animal Science, 3p
Barcelona, Cognition, Brain and technology summer school, 2 weeks
Publication methodology, 1 day
Perspective on learning
Perspective on course,
Problem based learning
BSc in Psychology
Lund University, 216 ECTS
University of California, Santa Barbara 77,3 ECTS, GPA: 3.97
Stockholm University, 30 ECTS, top grade
Cambridge University (UK), 7.5p, A+
IB Diploma Programme, Västergårdsgymnasiet (Södertälje), Sweden
2008-2011: Inst. Experimental Medical Science, Chairman for the PhD advisory committee
2008-2011: Inst. Experimental Medical Science, Board member
2005-2006: Solbergahemmets Institute, Järna, Carer for children with neuropsychiatric disorders, Part-time.
2002-2003: Mora Parks Institute, Carer for children with neuropsychiatric disorders, Full-time
2001-2002: ICA Supermarket, Järna, Janitor, Part-time