Anders Rasmussen, Postdoctoral Researcher Erasmus MC

Contact Information

Title: Postdoctoral Researcher, Erasmus MC, Netherlands

Nationality: Swedish & Danish

Languages: Swedish, English and Danish

Phone: +46 709 746609

Email: anders.rasmussen@med.lu.se; Gmail: an.rasmussen@gmail.com

Homepage: sites.google.com/site/anrasmussen83/

LinkedIn: linkedin.com/in/anders-rasmussen-b2324b64/

Researcher ID:-6157-2014; ORCID: 0000-0003-4477-369X

Twitter: https://twitter.com/rasmussenanders


Background

My focal research interest is in the neural mechanisms and the implications of timing ability. My multi-disciplinary approach spans from cell and molecular biology to behavioral neuroscience and psychology with a correspondingly broad spectrum of methods including transgenics; in vivo neurophysiology; pharmacology; behavioral assays; human neuroimaging, as well as behavioral studies on clinical and non-clinical human populations.

I started doing research as a psychology undergraduate, assisting Jean Christophe Rohner with his research on memory biases associated with the attractiveness stereotype. Later, I spent one year at the University of California, Santa Barbara (UCSB). There I had the privilege of helping Barry Giesbrecht with his research on the attentional blink and Osnat Ben-Shahar with research on cocaine addiction in rats. Back in Lund I completed my bachelor degree with a research project supervised by Mikael Johansson, where I looked at electrophysiological correlates of the attractiveness stereotype and swedish category norms.

During my PhD, supervised by Professor Germund Hesslow, I studied feedback mechanisms that regulate learning during eyeblink conditioning, and how cerebellar neurophysiology can help make sense of central learning theories such as the Rescorla-Wagner model. My colleague, Dan-Anders Jirenhed had previously shown that plastic changes in Purkinje cells, in the cerebellar cortex, play a critical role in eyeblink conditioning, I expand on this work by showing that these learning induced plastic changes that generate the learned response also influence the input that give rise to the learning in the first place.

My postdoctoral project, financed by the Swedish Research Council and EMBO, was inspired by Fredrik Johansson's research showing that blocking the mGluR7 receptor abolished previously learned cellular responses in the Purkinje cell that we believe drives the behavior. Using global and Purkinje cell specific knockouts, as well as pharmacological, histological and neurophysiological methods, I will try to elucidate the role that the mGluR7 receptor plays in several forms of motor learning (manuscript in preparation). In a side project we showed that caffeine, despite acting on receptors in the cerebellum, have no effect on eyeblink conditioning.

In parallel, I have initiated a research project aimed at comparing the learning and timing of voluntary and classically conditioned blink responses in humans and we have also studied the influence of age and sex on eyeblink conditioning.

Research Experience

  • 01/09/2018 – Present: Post-doctoral researcher, Erasmus MC, Netherlands
  • 01/01/2018 – 31/08/2018: Assistant researcher, Lund University, Sweden
  • 01/09/2015 – 31/12/2017: Post-doctoral fellow. Erasmus MC, Netherlands
  • 15/06/2014 – 31/08/2015: Assistant researcher in Neurophysiology. Professor Germund Hesslow’s lab, Lund University. Studying associative learning in humans
  • 01/02/2008 – 14/06/2014: PhD student. Professor Germund Hesslow’s lab, Lund University. Studying cellular mechanisms and feedback systems involved in associative learning
  • 15/09/2017 – 15/12/2007: Project assistant. Professor Mikael Johansson’s lab, Lund University. Studying EEG activity related to stereotypes and category norms in language
  • 01/04/2006 – 15/06/2006: Undergraduate assistant. Researcher Osnat Ben-Shahar’s lab, University of California, Santa Barbara. Studying operant conditioning and neuropharmacology
  • 01/10/2005 – 15/06/2006: Undergraduate assistant. Professor Barry Giesbrecht, University of California, Santa Barbara. Studying EEG activity and attention,
  • 01/09/2004 – 05/05/2005: Undergraduate assistant. Associate Professor Jean-Christophe Rohner’s lab, Lund University. Studying the physical attractiveness stereotype and memory biases

Publications

In total, I have published 19 papers (22 if you include two reports and my bachelor thesis which has received some international attention). Of these 19 papers, 3 were published in the prestigious journal Proceedings in the National Academy of Sciences (PNAS), 2 in the Journal of Neuroscience and 1 in Cell reports. I have been the first author on 9 and the corresponding author on 7 papers. As first or corresponding author, I performed the experiments, I led or contributed substantially to data analysis, I wrote the first draft of the manuscript and updated subsequent versions based on input from co-authors, I submitted the paper to a journal and handled the peer-review process all the way to the final publication. For each paper listed below, I provide the impact factor of the journal that published the paper based on information from web of science collected on August 8th, 2018. In the table and diagram below I also provide stats from web of science and google scholar, demonstrating my research progress.

Citation history: The number of citations I have received each year. Based on numbers from google scholar, collected on October 5th, 2018.

Original research articles (= equal contribution; C = Corresponding author)

  • Rasmussen AC, Ijpelaar ACHG, De Zeeuw CI, Boele HJ (2018) Caffeine has no effect on eyeblink conditioning in mice. Behavioural Brain Research [Impact Factor: 3.0; Citations: 0]. 30; 337:252-255. Pdf
  • Johansson F, Jirenhed D, Rasmussen A, Zucca R, Hesslow G. (2018) Absence of parallel fibre to Purkinje cell LTD during eyeblink conditioning. Scientific Reports [Impact Factor: 4.2; Citations: 0]. Pdf
  • Rasmussen AC, Jirenhed D (2017) Learning and timing of voluntary blink responses match eyeblink conditioning. Scientific Reports [Impact Factor: 4.2; Citations: 1]. 7:3404. Pdf
  • Jirenhed D, Rasmussen A, Johansson F, Hesslow G (2017) Learned response sequences in cerebellar Purkinje cells. Proceedings in the National Academy of Sciences [Impact Factor: 9.7; Citations: 10]. 114(23):6127-6132. Pdf
  • Löwgren K, Bååth R, Rasmussen A, Boele HJ, Koekkoek SKE, De Zeeuw CI, Hesslow G (2017) Performance in eyeblink conditioning is age and sex dependent. PLOS ONE [Impact Factor: 2.7; Citations: 4]. 12(5):e0177849. Pdf
  • Zucca R, Rasmussen A, Bengtsson F (2016) Climbing fiber regulation of spontaneous Purkinje cell activity and cerebellum-dependent blink responses. eNeuro [Impact Factor: NA (New Journal); Citations: 5]. 0067-15. Pdf
  • Rasmussen AC, Zucca R, Johansson F, Jirenhed D, Hesslow G (2015) Purkinje cell activity during classical conditioning with different conditional stimuli explains central tenet of Rescorla-Wagner model. Proceedings in the National Academy of Sciences National Academy Sciences [Impact Factor: 9.7; Citations: 6]. 112(45) 14060-5. Pdf
  • Johansson F, Carlsson HAE, Rasmussen A, Yeo CH, Hesslow G (2015) Activation of a Temporal Memory in Purkinje Cells by the mGluR7 Receptor. Cell Reports [Impact Factor: 8.3; Citations: 30]. 13(9):1741–6. Pdf
  • Johansson F, Jirenhed D, Rasmussen A, Zucca R, Hesslow G. (2014) Memory trace and timing mechanism localized to cerebellar Purkinje cells. Proceedings in the National Academy of Sciences [Impact Factor: 9.7; Citations: 66]. 111(41), 14930–14934. Pdf
  • Rasmussen AC, Jirenhed D, Wetmore DZ, Hesslow G (2014). Changes in complex spike activity during classical conditioning. Frontiers in Neural Circuits [Impact Factor: 3.0; Citations: 15]. 8(90). Pdf
  • Wetmore DZ, Jirenhed D, Rasmussen A, Johansson F, Schnitzer MJ, Hesslow G (2014). Bidirectional plasticity of Purkinje cells matches temporal features of learning. Journal of Neuroscience [Impact Factor: 6.0; Citations: 27]. 34(5):1731–1737. Pdf
  • Rasmussen AC, Zucca R, Jirenhed D, Johansson F, Örtenblad C, Svensson P, Hesslow G (2013). Golgi Cell Activity During Eyeblink Conditioning in Decerebrate Ferrets. Cerebellum [Impact Factor 3.2; Citations: 1]. 13(1): 42-45. Pdf
  • Rasmussen AC, Jirenhed D, Zucca R, Johansson F, Svensson P, Hesslow G (2013). Number of spikes in climbing fibers determines the direction of cerebellar learning. Journal of Neuroscience [Impact Factor: 6.0; Citations: 42]. 33(33), 13436–13440. Pdf
  • Rohner JC, Rasmussen A (2012). Recognition bias and the physical attractiveness stereotype. Scandinavian Journal of Psychology [Impact Factor: 1.3; Citations: 13]. 53(3), 239–246. Pdf
  • Rohner JC, Rasmussen A. (2011). Physical attractiveness stereotype and memory. Scandinavian Journal of Psychology [Impact Factor: 1.3; 7]. 52(4):309-319. Pdf
  • Rasmussen A, Jirenhed D, Hesslow G (2008). Simple and complex spike firing patterns in Purkinje cells during classical conditioning. Cerebellum [Impact Factor: 3.2; Citations: 46]. 7(4), 563–566. Pdf

Books

    • Rasmussen, A. (2014). Feedback control of cerebellar learning. Media Tryck. Doctoral thesis.

Review articles

  • Rasmussen AC, Hesslow G (2014). Feedback control of learning by the cerebello-olivary pathway. Progress in Brain Research [Impact Factor: 2.68; Citations: 13], 210:103–119. Pdf
  • Hesslow, G., Jirenhed, D., Rasmussen, A., & Johansson, F. (2013). Classical conditioning of motor responses: what is the learning mechanism? Neural Networks. [Impact Factor: 2.0; Citations: 32]. Pdf

Book chapters

  • Bengtsson F, Rasmussen A, Hesslow G. Feedback regulation of cerebellar learning. Invited book chapter, Handbook of the Cerebellum. In press (will be published late 2018 or early 2019)

Reports

  • Hellerstedt, R., Rasmussen, A., & Johansson, M. (2012). Swedish Category Norms. (M. Lindgren, Ed.). Lund Psychological Reports, 12. [Impact Factor: NA; Citations: 13]
  • Rohner, J.-C., & Rasmussen, A. (2007). Physical attractiveness stereotype and memory. (S.-B. Hansson & M. Lindgren, Eds.) Lund Psychological Reports, 8.

Submitted manuscripts

  • Kjell K, Löwgren K, Rasmussen AC. A longer interstimulus interval yields better learning in adults and young adolescents. Submitted to Frontiers in Human Neuroscience

Theses

  • Rasmussen A (2014). Feedback control of cerebellar learning. Media Tryck. Doctoral thesis. Lund University.
  • Rasmussen A (2006). Electrophysiology of stereotypes: N400 as a measure of the beautiful is good stereotype. Bachelor thesis. Supervisor: Mikael Johansson. Lund University. Citations: 3

Selected manuscripts in preparation

  • Rasmussen A, Boele HJ, Schonewill M, De Zeeuw CI. The role of mGluR7 on motor learning. In preparation
  • Löwgren K, Bååth R, Rasmussen AC. Performance on timing related tasks. In preparation
  • Rasmussen A. Inter-species Comparison of Eyeblink Conditioning. In preparation

Funding - Main applicant

  • 24/05/2018: Crafoord stiftelsen, Research grant, 80.000€
  • 14/12/2017: Stiftelsen Anna-Lisa Rosenberg’s fond för neurologisk forskning, 7000€
  • 24/06/2015: Swedish Research Council (VR), International Post-doc grant, 210.000€
  • 06/05/2015: European Molecular Biology Organization (EMBO). Long-term fellow, 120.000€
  • 15/09/2011: Fysiografens resebidrag, 1500€

Awards

  • 10/05/2015: Recipient of the Masao Ito prize awarded by the Society for Research on the Cerebellum
  • 01/10/2005 – 01/06/2006: 3x Dean’s Honors, University of California, Santa Barbara (UCSB)

External examiner

  • 09/05/2018: Halftime opponent for Anders Wahlbom, PhD candidate, Lund University
  • 05/12/2017: External examiner on PhD thesis defense for Michiel Ten Brinke, Erasmus MC
  • 24/11/2016: Halftime opponent for Jonas Enander, PhD candidate, Lund University
  • 02/03/2016: External examiner on PhD thesis defense for Jochen Spanke, Erasmus MC

Invited talks

  • 03/05/2018: Minimizing the role of volition in eyeblink conditioning, Lund University
  • 09/11/2017: The role of volition in eyeblink conditioning. University hospital Essen, Germany
  • 24/10/2016: The effect of mGluR7 antagonist injections on conditioned eyeblink responses, Erasmus MC, Rotterdam, Netherlands.
  • 05/10/2015: Talk on the molecular mechanisms for the generation of timed Purkinje cell pause responses, Erasmus MC, Rotterdam, Netherlands
  • 24/04/2015: Molecular mechanisms of conditioned blink responses Oxford University, United Kingdom

Editorial positions

  • 03/09/2018 – Present: Review Editor, Frontiers in Behavioral Neuroscience

Reviewer assignments

  • 22/02/2017 – 27/08/2018: 5 x Reviewer, Experimental Brain Research
  • 12/01/2017 – 20/04/2018 – 4 x Reviewer, Neuroscience letters
  • 11/11/2014: Reviewer, Frontiers in cellular Neuroscience
  • 20/03/2014: Reviewer, Journal of Social Psychology

Teaching and Supervisory Experience

  • 01/01/2016 – Present: Main supervisor for Karolina Löwgren, PhD candidate, Lund University
  • 03/04/2008 – Present: Lab demonstration supervisor. Lund Medical School,
  • 17/01/2008 – 01/06/2018: Tutor in Problem Based Learning. Lund Medical School
  • 01/10/2014 – 31/12/2015: Co-supervisor for Karolina Löwgren, PhD candidate, Lund University
  • 01/01/2010 - Present: Supervisor for students, on Bachelor, Master and PhD levels
  • 01/06/2011 – 31/08/2011: Student supervisor, Carolina Örtenblad for summer student

Public outreach

  • 12/03/2018 – 15/03/2018: Public lectures. ”Hjärnan – En tidsmaskin”. I held three lectures during ’NMT dagarna’. More than 5000 high-school students come to Lund to listen to inspirational lectures about science, medicine and technology (11-15th of March, Lund Sweden). https://goo.gl/FiuGyE
  • 28/06/2017: Press release: Överraskande exakt tajming av viljestyrda rörelser. Lund University press release. https://goo.gl/w2kJcZ
  • 01/02/2016: Popular science article. We learn and forget to correct our expectations. Atlas of science. Available at: https://goo.gl/qYNTvH
  • 27/10/2015: Press release. Hjärnan glömmer för att spara energi. Press release to inform public about findings published in PNAS. The press release was picked up by multiple news outlets and ranks in the top 5th percentile on altmetric. https://goo.gl/JNJifL
  • 13/10/2014: P4 Radio interview. Jankell i P4 om skönhetsideal. I was interviewed on Swedish national radio about my research on the interplay between memories and stereotypes. https://goo.gl/LE4cmX
  • 05/03/2011: SVT televised interview: “Vackra människor behandlas bättre”. An interview in Swedish national TV about my research on the beautiful is good stereotype. https://goo.gl/XAEMqV

Administrative Experience

  • 01/12/2008 – 06/01/2011: Inst. Experimental Medical Science, Chairman for the PhD advisory committee
  • 01/12/2008 – 06/01/2011: Inst. Experimental Medical Science, Board member

Conference Participation and poster presentations

  • 02/07/2016 – 06/07/2016: FENS, Federation of European Neuroscience Societies, 5 day meeting, Denmark
  • 24/06/2016 – 26/06/2016: Kavli futures symposium, 2 day symposium, Santa Barbara, California, USA
  • May 2015 - SRC, 2 day symposium. Brussels, Belgium, Poster + Oral presentation
    • Rasmussen A, Zucca R, Johansson F, Jirenhed DA, Hesslow G (2015) Learning induced pause responses in Purkinje cells reduce the probability that a subsequent periorbital stimulus elicits a complex spike.
  • 13/03/2013 – 15/03/2013: Translational Sensorimotor Neuroscience meeting. Johannesbergs Slott, Sweden. Participation + Poster presentation + oral presentation
    • Rasmussen A, Zucca R, Jirenhed DA, Johansson F, Hesslow G (2013). Direction of learning in cerebellar Purkinje cells dependent on number of climbing fiber impulses.
  • 01/05/2008 – 01/05/2013: Neuroscience day, Participaion + 4 poster presentations
    • Zucca, R, Rasmussen A., Johansson F, Verschure PF, Hesslow G (2012). Suppression of conditioned eye-blink responses through high frequency climbing fibres stimulation.
    • Rasmussen A, Zucca R, Jirenhed DA, Johansson F, Örtenblad C, Svensson P, Hesslow G (2012). Golgi Cell Activity during Eyeblink Conditioning in Decerebrate Ferrets. SFN, New Orleans, USA
    • Johansson F, Jirenhed DA, Rasmussen A, Zucca R, Hesslow G (2011). In vivo parallel fibre stimulation as conditional stimulus in Pavlovian conditioning of Purkinje neuron responses.
    • Rasmussen A, Johansson F, Zucca R, Hesslow G (2011). The neural foundation of overexpectation.
    • Zucca, R., Rasmussen, A., Herreros-Alonso, I., Verschure, P. F., & Hesslow, G. (2010). A closed-loop framework to investigate cerebellar learning in a decerebrated ferret preparation.
  • 27/05/2011 – 28/05/2011: Organization and Function of Neuronal Circuits in Movement Control, 2 day symposium. Trolleholm, Sweden
  • Fall 2008 - Motor Networks, 1 day conference, Lund, Sweden. Participation + Poster presentation
  • 09/12/2008 – 13/12/2008: Perceptual Learning, Motor Learning and Automaticity, Amsterdam, Netherlands, Participation + Poster presentation
    • Rasmussen, A., Jirenhed, D., & Hesslow, G. (2008). Olivary activity during Classical Conditioning.
  • 10/07/2008 – 12/07/2008: Society for Research on the Cerebellum, 2 day symposium. Geneva, Switzerland

Other relevant work experience

  • 10/06/2005 – 15/08/2006: Carer for children with ADHD and ASD. Solbergahemmet, Järna, Part-time.
  • 26/06/2002 –15/08/2003: Carer for children with neuropsychiatric disorders. Mora Parks, Järna, Full-time

Education

Pedagogical and postgraduate courses

  • 05/02/2018 – 07/02/2018: Laboratory management, 1p, EMBO
  • 10/10/2016 – 13/10/2016: Research Integrity - Biomedical Sciences, 0.5p, Epigeum
  • 14/11/2014 – 21/09/2012: Research supervision, 2p, MedCul, Lund University
  • 01/10/2012 – 10/01/2013: Perspective on course design, 4p, MedCul, Lund University
  • 04/06/2012 – 21/09/2012: MedCul Perspectives on learning, 3p, MedCul, Lund University
  • 01/04/2008 – 02/04/2008: Problem based learning, 0.5 weeks, MedCul, Lund University


PhD in Medical Science, Lund University, Sweden

  • Introductory course, 1p
  • Scientific communication 1.5p
  • Research ethics 1.5p
  • Oral communication, 1.5p
  • Laboratory Animal Science, 3p
  • Barcelona, Cognition, Brain and technology summer school, 2 weeks
  • Publication methodology, 1 day

BSc in Psychology

Lund University

  • Introductory Psychology, 30p
  • Neuropsychology, 15p
  • Social and Personality Psychology, 15p
  • Cognitive Psychology, 15p
  • Intercultural Psychology, 15p
  • Human-Computer interaction, 7.5p
  • Bachelor Thesis, methodology + thesis work, 30p
  • The nervous system and the movement apparatus, 28.5p
  • Statistics, 30p

University of California, Santa Barbara 77,25p, GPA: 3.97

  • Introductory Biology, 6p
  • Introductory Biology Lab, 1.5p
  • Issues in Biopsychology, 6p
  • Lab in Biopsychology, 7.5p
  • Neuroanatomy, 7.5p
  • Neuropharmacology, 6p
  • Research in Psychology, 13.5p
  • Evolution and Cognition, 6p
  • Devlopmental Psychology, 6p
  • Ecology, Evolution and Marine Biology (Intro Biology II), 3p
  • Molecular, cellular and developmental biology, 4.5p
  • Molecular, cellular and developmental biology lab, 1.5p
  • Endocrinology lab, 7.5p
  • Weight Training, 0.75p

Stockholm University, 30p , top grade

  • Criminology, 30p

Cambridge University (UK), 7.5p, A+

  • International Science Summer School, 7.5p

IB Diploma Programme (1999-2003)

  • Computer Science
  • Physics (higher level)
  • Psychology (higher level)
  • Mathematics (higher level)
  • English
  • Swedish