Science


Documents

Poster with summer student Cedric Kouam, presented at NIH Summer Poster Day 2016: Force Distribution across Neutrophil Microvilli Resists bonds Detachment (PDF)
Undisclosed Research Conference on Directed Cell Migration 2015 Poster: Directed and random boundary crossing in chemotaxis assays  (PDF)
Biophysical Society 2014 Poster: Neutrophil rolling on patches of selectin (PDF)

Software

I have made a tool, Bake, that makes doing numerical modeling parameter studies easy. The simulations for the videos below, and the videos themselves, were made with the help of Bake: Bake makes dealing with 12 or 100 runs as easy as dealing with 3.

Movies about cell rolling

Soft cell

Soft leukocyte (0.6 nN/micron) under 400/s shear rate. It detaches quickly from the surface.

Medium stiffness cell

Medium stiffness leukocyte (1.2 nN/micron) under 400/s shear rate. It lurches forward about halfway through the video.

Stiff cell

Stiff leukocyte (3.0 nN/micron) under 400/s shear rate. It doesn't deform very much.

Side view of cells rolling

Side view of cells rolling

Top view of cells rolling

Top view of cells rolling
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