Since our description of the molecular genetic basis of the three major alleles and several minor alleles, additional ABO alleles have been molecularly characterized and their sequence information has been deposited in the national database (http://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/home), which was established by Professor Olga Blumenfeld at Albert Einstein College of Medicine. Olsson, Chester, and colleagues (Hansen et al., 1998; Olsson and Chester, 1995, 1996a, b, c, 1998, 2001; Olsson et al., 1997; Olsson et al., 2001; Olsson et al., 1998; Olsson et al., 1995), Blancher and colleagues (Kermarrec et al., 1999; Roubinet et al., 2002; Roubinet et al., 2001), Seltsam, Blasczyk, and colleagues (Seltsam et al., 2002; Seltsam et al., 2003), Ogasawara and colleagues (Ogasawara et al., 1996a; Ogasawara et al., 1998; Ogasawara et al., 2001; Ogasawara et al., 1996b), and Yip and colleagues (Yip, 2000, 2002; Yip et al., 1996; Yip et al., 1995) played an important role in this expansion. The total number of defined alleles currently stands at 178, and the full listing of alleles is shown above. This table was prepared based on data culled from the dbRBC - Blood Group Antigen Gene Mutation Database. Blumenfeld, O. dbRBC - Blood Group Antigen Gene Mutation Database (http://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/home) Hansen, T., Namork, E., Olsson, M.L., Chester, M.A., and Heier, H.E. (1998). Different genotypes causing indiscernible patterns of A expression on A(el) red blood cells as visualized by scanning immunogold electron microscopy. Vox Sang 75, 47-51. Kermarrec, N., Roubinet, F., Apoil, P.A., and Blancher, A. (1999). Comparison of allele O sequences of the human and non-human primate ABO system. Immunogenetics 49, 517-526. Ogasawara, K.,
Bannai, M., Saitou, N., Yabe, R., Nakata, K., Takenaka, M., Fujisawa,
K., Uchikawa, M., Ishikawa, Y., Juji, T., et al. (1996a). Extensive
polymorphism of ABO blood group gene: three major lineages of the
alleles for the common ABO phenotypes. Human Genet 97, 777-783. Keywords Histo-blood group ABO system, blood group ABO system, ABO system, AB0 system, ABO blood groups, AB0 blood groups, ABO blood types, AB0 blood types, ABO genetic locus, ABO genes, ABO, AB0, A glycosyltransferases, B glycosyltransferases, glycosyltransferases, A transferase, B transferase, cell surface antigens, carbohydrate antigens, oligosaccharide antigens, oligosaccharides, complex carbohydrate antigens, complex carbohydrates, A antigen, B antigen, H antigen, red blood cell antigens, A/B antigens, ABH antigens, glycolipid, glycosphingolipids, glycoproteins, oligo sugars, red blood cells, RBC, blood transfusion, transfusion medicine, cell/tissue/organ transplantation, transplantation medicine, immunohematology, immunohaematology, immuno-hematology, immunology, ABO genotyping, forensic sciences, legal medicine, human genetics, population genetics, evolution, enzymology, glycobiology, glycosciences, human genes, primate genes, mouse gene, pig genes, alpha 1,3-Gal(NAc) transferases, a1,3-galactosyl transferase, a1,3-GalNAc transferase, structural basis, molecular genetic basis of ABO, ABO polymorphism, single nucleotide polymorphism, SNP, A, B, AB, O, A2, A3, Ax, B3, alleles, weak subgroups, homo sapiens, pig AO genes, cis-AB, B(A), mouse cis-AB gene, ABO genotype, ABO phenotype, DNA methylation, transcription, alternative splicing, Golgi apparatus, transferase chimeras, GBGT1, GGTA1, A3GALT2, monoclonal antibody, sera, plant lectins, Fumi-ichiro Yamamoto, Fumiichiro Yamamoto, F. Yamamoto, Landsteiner, enzyme, kinetics, sugar specificity, acceptor substrate specificity, acceptors, donors, sugars, nucleotide-sugars, genetic engineering, differential susceptibility to infectious diseases, differential cancer susceptibility, alterations in glycosylation in cancer, pancreatic cancer, diets, Peter D'Adamo, Blood type diets, neurobiology, Masahiko Nomi, personality, Burnham Institute, Burnham Institute for Medical Research, Biomembrane Institute, IMPPC, IMPPC Institute of Predictive and Personalized Medicine of Cancer, Institut de Medicina Predictiva i Personalitzada del Càncer, AABB, ISBT, dbRBC - Blood Group Antigen Gene Mutation Database |