Appendix 20. Comparison of amino acid sequences of the ABO and related genes

 

The deduced amino acid sequences are compared among the human A (A101), B (B101), O (O03), and cis-AB genes, mouse cis-AB gene, pig A gene, mouse and bovine alpha 1,3 galactosyltransferase genes, and dog Forssman synthase gene. They exhibited strong homology, suggesting that these genes are derived from a common ancestral gene.