Appendix 32. ABO Blood Type Diets
Opinions on “Blood Type Diets”
In his book entitled, “Eat Right 4 Your Type”, Peter D’Adamo claimed that human ABO blood type is the most important factor in determining a healthy diet, and proposed distinctive diets for individuals with different ABO blood groups. He reasoned that the reactions to lectins (carbohydrate-binding proteins) present in food depend on the individual ABO blood group and that the food containing incompatible and harmful lectins would better be avoided in order to minimize toxic reactions caused by lectin-A/B antigen interactions. This theory met with much skepticism and criticism from the medical and scientific community. Major criticisms have centered on the lack of scientific evidence and discrepancies with scientific norms. For example, lectins that possess high affinity to a particular ABO type are far less common in food, except for some beans. And actually no data were presented to correlate the kinds of lectins present in the diet and their ABO specificity.
Even if his theory is correct, it is impossible to propose right “Blood type diets ” without knowing which lectins (including those with low affinity) are contained or absent in which foods. Unless the presence of blood group-specific lectins is demonstrated in specific diets, the promotion of the “Blood type diets” is wrong. It may potentially harm people by proposing diets that may contain some lectins to cause problematic interactions and/or by suggesting them to avoid some foods of high nutrient value because of his mistaken assignments.
His belief that O, A, B, and AB blood types originated 30,000, 20,000, 10,000, and 1,000 years ago, respectively, does not fit with the current theory of the evolution of the ABO gene, either.
Although his best seller has contributed much to enhance the people’s interest in the ABO blood groups, Dr. D’Adamo’s proposed “Blood type diets” have nothing to do with the ABO blood types.
Histo-blood group ABO system, blood group ABO system, ABO system, AB0 system, ABO blood groups, AB0 blood groups, ABO blood types, AB0 blood types, ABO genetic locus, ABO genes, ABO, AB0, A glycosyltransferases, B glycosyltransferases, glycosyltransferases, A transferase, B transferase, cell surface antigens, carbohydrate antigens, oligosaccharide antigens, oligosaccharides, complex carbohydrate antigens, complex carbohydrates, A antigen, B antigen, H antigen, red blood cell antigens, A/B antigens, ABH antigens, glycolipid, glycosphingolipids, glycoproteins, oligo sugars, red blood cells, RBC, blood transfusion, transfusion medicine, cell/tissue/organ transplantation, transplantation medicine, immunohematology, immunohaematology, immuno-hematology, immunology, ABO genotyping, forensic sciences, legal medicine, human genetics, population genetics, evolution, enzymology, glycobiology, glycosciences, human genes, primate genes, mouse gene, pig genes, alpha 1,3-Gal(NAc) transferases, a1,3-galactosyl transferase, a1,3-GalNAc transferase, structural basis, molecular genetic basis of ABO, ABO polymorphism, single nucleotide polymorphism, SNP, A, B, AB, O, A2, A3, Ax, B3, alleles, weak subgroups, homo sapiens, pig AO genes, cis-AB, B(A), mouse cis-AB gene, ABO genotype, ABO phenotype, DNA methylation, transcription, alternative splicing, Golgi apparatus, transferase chimeras, GBGT1, GGTA1, A3GALT2, monoclonal antibody, sera, plant lectins, Fumi-ichiro Yamamoto, Fumiichiro Yamamoto, F. Yamamoto, Landsteiner, enzyme, kinetics, sugar specificity, acceptor substrate specificity, acceptors, donors, sugars, nucleotide-sugars, genetic engineering, differential susceptibility to infectious diseases, differential cancer susceptibility, alterations in glycosylation in cancer, pancreatic cancer, diets, Peter D'Adamo, Blood type diets, neurobiology, Masahiko Nomi, personality, Burnham Institute, Burnham Institute for Medical Research, Biomembrane Institute, IMPPC, IMPPC Institute of Predictive and Personalized Medicine of Cancer, Institut de Medicina Predictiva i Personalitzada del Càncer, AABB, ISBT, dbRBC - Blood Group Antigen Gene Mutation Database