12. ABO Genotyping of Blood Specimens
In order to examine whether the identified changes were common or uncommon, we next examined the RFLP of genomic DNAs prepared from blood specimens with known ABO types. We analyzed 14 specimens with a variety of ABO types. Based on the RFLP results, we deduced the ABO genotypes of the individual specimens and later compared them with the ABO types of the specimens. We did not find any contradictions, suggesting that those differences in the nucleotide sequences are commonly present.
Yamamoto, F., Clausen, H., White, T., Marken, J., and Hakomori, S. (1990). Molecular genetic basis of the histo-blood group ABO system. Nature 345, 229-233. (http://www.nature.com/nature/journal/v345/n6272/abs/)
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