27. Transfection Results (A-B Transferase Chimeras --BA)

 

Finally, when the last 2 amino acids were M of B transferase and G of A transferase, the constructs strongly expressed both A and B antigens. This became the first demonstration where we successfully modified the specificities of glycosyltransferases by genetic engineering and created novel enzymes with both strong A and B transferase activities.

28. Transfection Results (A transferase Codon 268)

01. ABO Blood Group System