The University of Houston (U of H) is a public research university in Houston, Texas. Founded in 1927, U of H is the flagship institution of the University of Houston System and the third-largest university in Texas with over 46,000 students. Its campus spans 667 acres (2.70 km²) in southeast Houston, and was known as University of Houston–University Park from 1983 to 1991. The university is classified among "R1: Doctoral Universities – Very high research activity".

The university offers more than 282 degree programs through its 14 academic colleges on campus—including programs leading to professional degrees in architecture, law, optometry, and pharmacy. The institution conducts $150 million annually in research, and operates more than 40 research centers and institutes on campus. Interdisciplinary research includes superconductivity, space commercialization and exploration, biomedical sciences and engineering, energy and natural resources, and artificial intelligence. Awarding more than 9,000 degrees annually, U of H's alumni base exceeds 260,000. The economic impact of the university contributes over $3 billion annually to the Texas economy, while generating about 24,000 jobs. The HPE Data Science Institute was created in 2017, and was named by the Hewlett Packard Enterprise Data Science Institute with its 10 million gift.

The University of Houston hosts a variety of theatrical performances, concerts, lectures, and events. It has more than 400 student organizations and 17 intercollegiate sports teams. Annual U of H events and traditions include The Cat's Back, Homecoming, and Frontier Fiesta. The university's varsity athletic teams, known as the Houston Cougars, are members of the American Athletic Conference and compete in the NCAA Division I in all sports. The football team regularly makes bowl game appearances, and the men's basketball team has made 22 appearances in the NCAA Division I Tournament—including six Final Four appearances. The men's golf team has won 16 national championships—the most in NCAA history.