The Cd117 gene controls differentiation or specialization of blood cells. As the cell becomes more specialized, less and less Cd117 is expressed.
Cross out 1 checkmark from Cd117 on your Gene Expression Chart.
Everyone’s cell is a little more specialized than it was at the beginning when you were an HSC. Since all cell have differentiated at least a little, Cd117 is now expressed a little less.
Remove two pushpins from your model.
(recall that the pushpins represented Cd117 expression)