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Make your blood stem cell
Make your blood stem cell
Make your own blood stem cell by making a small ball of clay.
This will be your hematopoietic stem cell (HSC) that resides in the bone marrow.
DIVIDE!
DIVIDE!
Your blood stem cell is signaled to divide.
What does your cell need to do before it can divide?
Grow in size.
Make more organelles.
Duplicate its DNA.
Model this process:
Add more clay to double the size of your stem cell.
Then, divide the cell into two identical cells.
Specialization begins
Specialization begins
One cell will stay a blood stem cell and will not become specialized yet; it will remain in the bone marrow. Put this cell aside aside.
The other daughter cell is going to become a mature blood cell by becoming specialized.
Remember, both of these cells contain the same DNA.
Let's turn on some genes
Let's turn on some genes
Cells become specialized by turning on or activating specific genes (DNA).
Remember that genes code for proteins, so when genes are ‘turned on’, the protein they code for is actively being made.
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