I made this image in SketchClub by filling a layer with a raspberry red color, and on a layer above that, drawing with a pen lines of slightly different colors. I saved the image to my camera roll.

Then I used various presets under Form/Deforms to create these images. I saved them to my camera roll. Instead of doing all the steps I did, you could just open a blank white canvas in iColorama and use Brush/Paint to paint some black lines or curves on it, using a hard round brush.

I processed it in iColorama using Effect/Glow at low to medium opacity to smooth the image. Then I used the last preset under Style/Water with the distortion slider set to zero and the texture and opacity sliders set to low, to simplify the image. Then I used Adjust/Levels to add contrast that was lost in the Water step. I saved the image to my camera roll. You could use a photograph instead of a painting; in that case I would also simplify the image as needed. Adding effects, like we will be doing with our "negative" effect, always makes for a more complex image, so it helps to prepare your base image first to simplify it, particularly to get rid of any distracting background, and to focus in on the main subject. You will see how I will further simplify the painting in my next steps.

On a new layer below the face layer, I filled the layer with a reddish color. On a new layer above that, I painted with a slightly different red color. Then on another new layer above that, I made some strokes with a slightly different red color. This way I got a background that is not just a flat color but has some variation to it. This is a cleaner background than the painted background in the original painting. Then on a layer above the face layer, I painted a shape for her shirt. On layers above that I used an airbrush to paint highlights and shadows on her shirt. I used an eraser to remove color that strayed outside the shirt. Then on a new layer above that, I used a pen to draw lines and hatch marks over her shirt. This essentially replaces her busy plaid shirt with a simple red shirt. Then on a new layer above that, I painted a pale yellow shape for her hair. Then on a new layer above that, I used a pen to draw curls in slightly different colors. This simplifies her hair quite a bit. On a layer just above the face layer, I painted over her face to smooth the brushmarks from the skin, and I also replaced the eyes with cleaner eyes by painting over them. I saved the image to my camera roll.

I opened the image in Elasticam and changed the shape of the face. I saved the image to my camera roll.