About nanotech laboratory

Our pioneering team at NanoTech Laboratory has relentlessly explored the potential of mesoporous silica and lipid nanoparticles. Our laboratory stands at the forefront of this dynamic research area. The major limitation of the lipid nanocarrier is its low drug-loading capacity because of its crystalline structure, which is subdued via inorganic nanocarriers, that is, mesoporous silica nanoparticles. The synthesis of mesoporous silica nanoparticles is underway, where we provide an anchorage to the tunability of MSNs – particle size, surface morphology, and pore size – to achieve excellent control over drug encapsulation and release. This meticulous approach leads to superior protection of the encapsulated therapeutic agent, shielding it from premature degradation or metabolism.  Furthermore, our ongoing research actively explores the potential of MSNs for site-specific controlled drug release and enhanced stability within the body. Beyond these fundamental advancements, our laboratory is particularly interested in harnessing the unique properties of MSNs for tumor treatment and imaging. Our work envelops the amelioration of the drug loading capacity, which will conclusively enhance the bioavailability. Our groundbreaking work in this area holds immense promise for developing targeted and efficacious therapies with application in areas of Alzheimer’s disease, Breast cancer, and Rheumatoid arthritis. This research thrust only provides a glimpse into the vibrant research landscape within our laboratory, where we continuously strive to push the boundaries of mesoporous silica nanoparticle technology to improve drug delivery.

Biosketch

Dr. Amit Alexander is presently working as an Associate Professor in the Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER-Guwahati), under the aegis of the Department of Pharmaceuticals (DoP), Ministry of Chemicals and Fertilizers, Government of India (GoI). Dr. Alexander has teaching and research experience of more than 16 years. He is an Elected member of the Royal Society of Chemistry (MRSC), London, United Kingdom (UK); Royal Society of Biology (MRSB), London, United Kingdom (UK); Controlled Release Society-Indian Local Chapter (CRS-IC), Mumbai; Indian Academy of Neuroscience (IAN) and a life fellow of Indian Chemical Society (FICS), Kolkata. To his credit, he has more than 175 scientific publications with a cumulative impact factor of 606.67 in High-impact factor, SCI-indexed, peer-review journals. He has 14 papers published in the Journal of Controlled Release, Elsevier having an Impact Factor 10.8. His publications Google Scholar citations are 8528, H index: 48, and i10 index: 111. 

Dr. Alexander is also serving as Co-Ordinator of Bio-NEST Incubation Center at NIPER-G, a project funded by DBT/BIRAC, GoI, to encourage/help the traditional healers for scientific standardization and commercialization of their products while incubating the other researchers by offering appropriate mentoring and infrastructural support. Phase I of the project has been successfully completed, and Phase II is now going on. Dr. Alexander also manages the Atal Incubation Centre (AIC) NIPER-Guwahati Foundation as the Board of Directors, supported by the Atal Innovation Mission, NITI AAYOG, Government of India.

Dr. Alexander has received many National and International Awards, the Young Scientist Award 2013, the Young Researcher Award 2020, and the UGC-JRF National Fellowship 2011, and secured a Best research presentation position at many National seminal/conferences. He has been recognized as one of the Top 2% Scientific Ranking Worldwide by Stanford University for four consequent years (2020, 2021, 2022, and 2023). At Global platform, he holds the position of Associate Editor in Heliyon, Cell Press, Elsevier Inc., section: Pharmaceutical Sciences, Pharmacology and Toxicology (Impact Factor: 4.0. Also, Review Editor in Biomaterial: Frontiers in Molecular Biosciences, Bioengineering and Biotechnology and Materials, Frontier and Editorial Board Member in Drug Delivery Letters, Bentham Sciences. Dr. Alexander also serves as a Reviewer in many SCI/SCOPUS indexed High Impact Factor journals of renowned publications, including Elsevier, ACS, Taylor & Francis, Natures, Springer-Nature, Springer, Dove Press, Wiley, Frontier, etc. 

His key research areas are the formulation of Novel Drug Delivery Systems for Alzheimer’s Disease and tumor targeting. His lab is also working on the formulation of In-Situ Injectable Hydrogels and synthesis of mesoporous silica nanoparticles, including lipid nanoparticles, etc., with expertise in Pharmacokinetic assessments, QbD, and other statistical designs.