UPDATES

POLS – call for research projects led by incoming researchers in Polish research organisations


The National Science Centre is currently conducting the POLS call for research projects to be carried out by incoming researchers in Polish research institutions or enterprises. Proposals may be submitted by researchers holding at least a PhD degree who have not resided, worked or studied in Poland or managed a research project carried out in Poland for 2 years prior to the call deadline. The objective of the call is to support researcher mobility and the arrival of renowned and promising scientists will serve to boost the research potential of Polish research entities.


The POLS call is funded from the Norway Grants and the budget of the call equals over €7 million. The requested amount of funding for the entire duration of the project must fall between €100,000 and €200,000. Grants may be designated to fund the salary for the research team, depreciation or purchase of research equipment, materials and services, costs of business trips and conferences as well as other project-related costs. The amount of indirect costs is 25% of the funds applied for to complete the project, including the value of research equipment purchased but excluding the sub-contracting costs.

The detailed information on the call can be found at:

ncn.gov.pl/ogloszenia/konkursy/pols?language=en


The call is open to researchers from all research domains. Proposals must be submitted electronically to the OSF system (osf.opi.org.pl/app/) by 16 June 2020, 4 p.m.



The Centre is organising an info chat during which we will be answering questions concerning the POLS call.

The chat will take place on 28 May 2020 at 12.00 (CEST) and will last for one hour.

The link to the chat will be available in advance through the NCN web site at:

ncn.gov.pl/eeanorwaygrants/news?language=en

Brain Tumor Meeting 2019 - Berlin


Recently, we attanded the Brain Tumor Meeting held in Berlin at The Max Delbrück Center for Molecular Medicine. The group had the opportunity to present oral and poster presentations. This gave us opportunity to dissaminate and showcase our research.


Following projects were presented at the meeting:

Bożena Kamińska - 'Development of synthetic peptides targeting glioma-microglia interaction as a new therapeutics.'

Iwona Ciechomska - 'EGFR/FOXO3A/BIM signalling pathway determines chemosensitivity of BMP4-differentiated glioma stem-like cells to temozolomide.'

Aleksandra Ellert-Miklaszewska - 'Expression and function of NFAT (Nuclear Factor of Activated T cells) trancription factors in human gliomas.'

Agnieszka Kaczmarczyk - 'Noverl mutations in the RECQL4 gene contribute to the glioma pathogenesis.'

Sylwia K Król - 'Effects of helicase RECQL4 depletion of human glioma biology and chemosensitivity.'

Maria Pasierbińska - 'Blocking Osteopontin signalling inhibits glioma invasivness ad reduces tumor growth of intracranial human glioma in Nude mice.'

Katarzyna Poleszak - 'The role of tumor-derived Granulocyte Macrophage Colony Stimulating Factor (GM-CSF/CSF2) in regulation of microglia-dependent invasion in gliomas.'

Paweł Segit - 'Single-cell RNA-seq of glioma associated microglia and macrophages reveals cell type-specific and sex-specific differences.'

Kacper A Walentynowicz - 'Dissecting tumor associated microglia/macrophages responses in preclinical model of glioblastoma.'

Kamil Wojnicki - 'New insights into the role of BLM helicase in malignant gliomas.'

"Compositions and methods for treating glioma" US and Japan patent


Prof Kaminska has received a patent for innovative method employing synthetic peptides that block crosstalk between tumor cells and microenvironment for brain tumor therapy. Tumor cells produce various factors that influence surrounding non-tumor cells and transform them into tumor-supporting phenotype. The synthetic peptides target tumor secreting GM-CSF (granulocyte-macrophage colony-stimulating factor) and proteins acting through integrin receptors through RGD motifs. Application of these peptides block tumor invasion and growth in vivo.


The recepiant of the patent are Prof. Bożena Kamińska, Dr Małgorzata Sielska, Dr Paweł Wiśniewski, and Dr Aleksandra Ellert-Miklaszewska with ownership to Glia Sp. z o.o. Patent is also under consideration in Europe, Israel, and Canada.

Our integration/workshop retreat


We have visited Uniejów (nearby Łódź) to take part in the lab integration retreat where we also took part in workshop on statistics for biologists.

During the retreat we were also able to visit local castle and thermal waters. On site we participated in beer tasting and food paring sessions. The statistics workshop was led by Dr Jakub Mieczkowski which was followed by a lively discussion on our day-to-day data analysis.