PUBLICATIONS

2021

Ramachandran S, Ma TS, Griffin J, Ng N, Foskolou IP, Hwang MS, Victori P, Cheng WC, Buffa FM, Leszczynska KB, El-Khamisy SF, Gromak N, Hammond EM. Hypoxia-induced SETX links replication stress with the unfolded protein response. Nat Commun. 2021 Jun 17;12(1):3686. [ PubMed ]

Stępniak K, Machnicka MA, Mieczkowski J, Macioszek A, Wojtaś B, Gielniewski B, Poleszak K, Perycz M, Król SK, Guzik R, Dąbrowski MJ, Dramiński M, Jardanowska M, Grabowicz I, Dziedzic A, Kranas H, Sienkiewicz K, Diamanti K, Kotulska K, Grajkowska W, Roszkowski M, Czernicki T, Marchel A, Komorowski J, Kaminska B, Wilczyński B. Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas. Nat Commun. 2021 Jun 15;12(1):3621. [ PubMed ]

You H, Wei L, Kaminska B. Emerging insights into origin and pathobiology of primary central nervous system lymphoma. Cancer Lett. 2021 Jul 1;509:121-129. [ PubMed ]

Ochocka N, Kaminska B. Microglia Diversity in Healthy and Diseased Brain: Insights from Single-Cell Omics. Int J Mol Sci. 2021 Mar 16;22(6):3027. [ PubMed ]

Ochocka N*, Segit P*, Walentynowicz KA, Wojnicki K, Cyranowski S, Swatler J, Mieczkowski J, Kaminska B Single-cell RNA sequencing reveals functional heterogeneity and sex differences of glioma-associated brain macrophages (2021) Nat Commun 12(1):1151. [PubMed]

Roura AJ, Gielniewski B, Pilanc P, Szadkowska P, Maleszewska M, Krol SK, Czepko R, Kaspera W, Wojtas B, Kaminska B. Identification of the immune gene expression signature associated with recurrence of high-grade gliomas. J Mol Med (Berl). 2021 Feb;99(2):241-255. [ PubMed ]

Ellert-Miklaszewska A, Ciechomska IA, Kaminska B. Synthetic Cannabinoids Induce Autophagy and Mitochondrial Apoptotic Pathways in Human Glioblastoma Cells Independently of Deficiency in TP53 or PTENTumor Suppressors. Cancers (Basel). 2021 Jan 22;13(3):419. [ PubMed ]

Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, ... Iwona A Ciechomska et al., Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. [ PubMed ]

Maleszewska M, Steranka A, Smiech M, Kaza B, Pilanc P, Dabrowski M, Kaminska B. Sequential changes in histone modifications shape transcriptional responses underlying microglia polarization by glioma. Glia. 2021 Jan;69(1):109-123. [ PubMed ]

Chen J, Ellert-Miklaszewska A, Garofalo S, Dey AK, Tang J, Jiang Y, Clément F, Marche PN, Liu X, Kaminska B, Santoni A, Limatola C, Rossi JJ, Zhou J, Peng L. Synthesis and use of an amphiphilic dendrimer for siRNA delivery into primary immune cells. Nat Protoc. 2021 Jan;16(1):327-351. [ PubMed ]


2020


Malik AR, Willnow TE. VPS10P Domain Receptors: Sorting Out Brain Health and Disease. Trends Neurosci. 2020 Nov;43(11):870-885.[ PubMed ]

Król SK, Kaczmarczyk A, Wojnicki K, Wojtas B, Gielniewski B, Grajkowska W, Kotulska K, Szczylik C, Czepko R, Banach M, Kaspera W, Szopa W, Marchel A, Czernicki T, Kaminska B. (2020) Aberrantly Expressed RECQL4 Helicase Supports Proliferation and Drug Resistance of Human Glioma Cells and Glioma Stem Cells. Cancers (Basel). 12(10):2919. [ PubMed ]

Ciechomska IA, Gielniewski B, Wojtas B, Kaminska B, Mieczkowski J. (2020) EGFR/FOXO3a/BIM signaling pathway determines chemosensitivity of BMP4-differentiated glioma stem cells to temozolomide. Exp Mol Med. 52(8):1326-1340. [ PubMed ]

Sielska M, Przanowski P, Pasierbińska M, Wojnicki K, Poleszak K, Wojtas B, Grzeganek D, Ellert-Miklaszewska A, Ku MC, Kettenmann H, Kaminska B. (2020) Tumour-derived CSF2/granulocyte macrophage colony stimulating factor controls myeloid cell accumulation and progression of gliomas. Br J Cancer. 123(3):438-448. [ PubMed ]

Malik AR, Lips J, Gorniak-Walas M, Broekaart DWM, Asaro A, Kuffner MTC, Hoffmann CJ, Kikhia M, Dopatka M, Boehm-Sturm P, Mueller S, Dirnagl U, Aronica E, Harms C, Willnow TE. SorCS2 facilitates release of endostatin from astrocytes and controls post-stroke angiogenesis. Glia. 2020 Jun;68(6):1304-1316. [ PubMed ]

You H, Baluszek S, Kaminska B. (2020) Supportive roles of brain macrophages in CNS metastases and assessment of new approaches targeting their functions. Theranostics.10(7):2949-2964. [ PubMed ]

Swiatek-Machado K, Kaminska B. (2020) STAT Signaling in Glioma Cells. Adv Exp Med Biol. 1202:203-222. [ PubMed ]

Ellert-Miklaszewska A, Poleszak K, Pasierbinska M, Kaminska B. (2020) Integrin Signaling in Glioma Pathogenesis: From Biology to Therapy.Int J Mol Sci. 21(3):888. [ PubMed ]

Kaminska B, Cyranowski S. (2020) Recent Advances in Understanding Mechanisms of TGF Beta Signaling and Its Role in Glioma Pathogenesis. Adv Exp Med Biol.1202:179-201. [ PubMed ]

Ellert-Miklaszewska A, Ciechomska IA, Kaminska B. (2020) Cannabinoid Signaling in Glioma Cells. Adv Exp Med Biol. 2020;1202:223-241. [ PubMed ]

Ciechomska IA, Jayaprakash C, Maleszewska M, Kaminska B. (2020) Histone Modifying Enzymes and Chromatin Modifiers in Glioma Pathobiology and Therapy Responses. Adv Exp Med Biol.1202:259-279. [ PubMed ]


2019

Malik AR, Willnow TE. Excitatory Amino Acid Transporters in Physiology and Disorders of the Central Nervous System. Int J Mol Sci. 2019 Nov 12;20(22):5671. [ PubMed ]

Wylot B, Mieczkowski J, Niedziolka S, Kaminska B, Zawadzka M. (2019) Csf1 Deficiency Dysregulates Glial Responses to Demyelination and Disturbs CNS White Matter Remyelination. Cells. 9(1):99. [ PubMed ]


You H, Baluszek S, Kaminska B. (2019) Immune Microenvironment of Brain Metastases-Are Microglia and Other Brain Macrophages Little Helpers? Front Immunol. 2019 Aug 20;10:1941 [ PubMed ]


Rajan WD, Wojtas B, Gielniewski B, Miró-Mur F, Pedragosa J, Zawadzka M, Pilanc P, Planas AM, Kaminska B. (2019) Defining molecular identity and fates of CNS-border associated macrophages after ischemic stroke in rodents and humans. Neurobiol Dis. 2020 Apr;137:104722. [ PubMed ]


Ellert-Miklaszewska A, Ochocka N, Maleszewska M, Ding L, Laurini E, Jiang Y, Roura AJ, Giorgio S, Gielniewski B, Pricl S, Peng L, Kaminska B. (2019) Efficient and innocuous delivery of small interfering RNA to microglia using an amphiphilic dendrimer nanovector. Nanomedicine (Lond). (18):2441-2458 [ PubMed ]


Przanowski P, Mondal SS, Cabaj A, Dębski KJ, Wojtas B, Gielniewski B, Kaza B, Kaminska B, Dabrowski M. (2019) Open chromatin landscape of rat microglia upon proinvasive or inflammatory polarization. Glia. (12):2312-2328 [ PubMed ]


You H, Baluszek S, Kaminska B. (2019) Immune Microenvironment of Brain Metastases-Are Microglia and Other Brain Macrophages Little Helpers? Front Immunol. 10:1941 [ PubMed ]


Przanowski P, Mondal SS, Cabaj A, Dębski KJ, Wojtas B, Gielniewski B, Kaza B, Kaminska B, Dabrowski M. (2019) Open chromatin landscape of rat microglia upon proinvasive or inflammatory polarization. Glia. 2019 Jul 24. [ PubMed ]


Kulesza DW, Ramji K, Maleszewska M, Mieczkowski J, Dabrowski M, Chouaib S, Kaminska B. (2019) Search for novel STAT3-dependent genes reveals SERPINA3 as a new STAT3 target that regulates invasion of human melanoma cells. Lab Invest. doi: 10.1038/s41374-019-0288-8 [ PubMed ]


Kulesza DW, Przanowski P, Kaminska B. (2019) Knockdown of STAT3 targets a subpopulation of invasive melanoma stem-like cells. Cell Biol Int. 43(6):613-622 [ PubMed ]


Kaminska B, Czapski B, Guzik R, Król SK, Gielniewski B. (2019) Consequences of IDH1/2 Mutations in Gliomas and an Assessment of Inhibitors Targeting Mutated IDH Proteins. Molecules. 24(5) [ PubMed ]


Wojtas B, Gielniewski B, Wojnicki K, Maleszewska M, Mondal SS, Nauman P, Grajkowska W, Glass R, Schüller U, Herold-Mende C, Kaminska B. (2019) Gliosarcoma Is Driven by Alterations in PI3K/Akt, RAS/MAPK Pathways and Characterized by Collagen Gene Expression Signature. Cancers 11(3) [ PubMed ]


Glemžaitė M, Zentelytė A, Wojtas B, Baronaitė S, Krasovskaja N, Savickienė J, Gielniewski B, Kaminska B, Utkus A, Navakauskienė R. (2019) DNMT inhibitors effectively induce gene expression changes suggestive of cardiomyogenic differentiation of human amniotic fluid-derived mesenchymal stem cells via chromatin remodeling. J Tissue Eng Regen Med. 13(3) doi: 10.1002/term.2800. [ PubMed ]


Was H, Krol SK, Rotili D, Mai A, Wojtas B, Kaminska B, Maleszewska M. (2019) Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells. Clin Epigenetics. 11(1) [ PubMed ]



2018

Rajan WD, Wojtas B, Gielniewski B, Gieryng A, Zawadzka M, Kaminska B. (2018) Dissecting functional phenotypes of microglia and macrophages in the rat brain after transient cerebral ischemia. Glia 67(2) [ PubMed ]


Ciechomska IA (2018) The role of autophagy in cancer – characterization of crosstalk between apoptosis and autophagy; autophagy as a new therapeutic strategy in glioblastoma. Postępy Biochem 64 (2–3) 119 - 128. [ PubMed ]


Ellert-Miklaszewska A, Pasierbinska M. Poleszak K, Kaminska B. (2018) Molecular interactions between tumor and its microenvironment in malignant gliomas. Postępy Biochemi64 (2–3) 129 - 140. [ PubMed ]


Maleszewska M, Wojtas B, Kaminska B. (2018) Deregulation of epigenetic mechanisms in cancer. Postępy Biochem 64 (2–3) 148 - 156. [ PubMed ]


Ciechomska IA, Marciniak MP, Jackl J, Kaminska B (2018) Pre-treatment or Post-treatment of Human Glioma Cells With BIX01294, the Inhibitor of Histone Methyltransferase G9a, Sensitizes Cells to Temozolomide. Front. Pharmacol. 9:1271 [ PubMed ]


Grabherr MG, Kaminska B, Komorowski J (2018) Special Issue Introduction: The Wonders and Mysteries Next Generation Sequencing Technologies Help Reveal. Genes (Basel) 9(10) [ PubMed ]


Ulanska-Poutanen J, Mieczkowski J, Zhao C, Konarzewska K, Kaza B, Pohl HBF, Bugajski L, Kaminska B, Franklin RJM, Zawadzka M. (2018) Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells. eLife 7:e30325 [ PubMed ]


Guneykaya, D., Ivanov, A., Hernandez, D.P., Haage, V., Wojtas, B., Meyer, N., Maricos, M., Jordan, P., Buonfiglioli, A., Gielniewski, B., Ochocka, N., Cömert, C., Friedrich, C., Artiles, L.S., Kaminska, B., Mertins, P., Beule, D., Kettenmann, H., Wolf, S.A. (2018) Transcriptional and Translational Differences of Microglia from Male and Female Brains. Cell Reports, 24(10),P2773-2783.e6 [ PubMed ]


Mieczkowski J, Tolstorukov MY. (2018) Bioinformatic Analysis of Nucleosome and Histone Variant Positioning. Methods Mol Biol.1832:185-203. [ PubMed ]


Pedragosa J, Salas-Perdomo A, Gallizioli M, Cugota R, Miró-Mur F, Briansó F, Justicia C, Pérez-Asensio F, Marquez-Kisinousky L, Urra X, Gieryng A, Kaminska B, Chamorro A, Planas AM. (2018) CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage. Acta Neuropathol Commun. 9(1):76. [ PubMed ]


Walentynowicz KA, Ochocka N, Pasierbinska M, Wojnicki K, Stepniak K, Mieczkowski J, Ciechomska IA, Kaminska B. (2018) In Search for Reliable Markers of Glioma-Induced Polarization of Microglia. Front. Immunol. 9:1329. doi: 10.3389/fimmu.2018.01329 [ PubMed ]


Czapski B, Baluszek S, Herold-Mende C, Kaminska B. (2018) Clinical and immunological correlates of long term survival in glioblastoma. Contemp Oncol 22(1A):81-85. [ PubMed ]


Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L , Weinstein J, Kaminska B, Huelsken J , Omberg L, Gevaert O, Colaprico A, Czerwińska P, Mazurek S , Mishra L, Heyn H, Krasnitz A , Andrew K. Godwin AK, Lazar LJ, The Cancer Genome Atlas Research Network, Stuart MJ, Hoadley KA, Laird PW , Noushmehr H, Wiznerowicz M. (2018) Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell, 173 (2): 338–354.e15. [ PubMed ]


Janus P, Szołtysek K, Zając G, Stokowy T, Walaszczyk A, Widłak W, Wojtaś B, Gielniewski B, Iwanaszko M, Braun R, Cockell S, Perkins ND, Kimmel M, Widlak P. (2018) Pro-inflammatory cytokine and high doses of ionizing radiation have similar effects on the expression of NF-kappaB-dependent genes. Cell Signal. 46:23-31. [ PubMed ]

Dabrowski, M.J., Draminski, M., Diamanti, K., Stepniak, K., Mozolewska, M.A., Teisseyre, P., Koronacki, J., Komorowski, J., Kaminska, B., Wojtas, B. (2018) Unveiling new interdependencies between significant DNA methylation sites, gene expression profiles and glioma patients survival. Sci Rep. 8(1):4390. doi:10.1038/s41598-018-22829-1 [ PubMed ]


2017

Gieryng A, Pszczolkowska D, Bocian K, Dabrowski M, Rajan WD, Kloss M, Mieczkowski J, Kaminska B. (2017) Immune microenvironment of experimental rat C6 gliomas resembles human glioblastomas. Sci Rep. 7(1):17556. [ PubMed ]

Garofalo S, Porzia A, Mainiero F, Di Angelantonio S, Cortese B, Basilico B, Pagani F, Cignitti G, Chece G, Maggio R, Tremblay E, Savage J, Bisht K, Esposito V, Bernardini G, Seyfried T, Mieczkowski J, Stepniak K, Kaminska B, Santoni A, Limatola C. (2017) Environmental stimuli shape microglial plasticity in glioma. Elife. 2017 Dec 29;6. pii: e33415. [ PubMed ]

Was H, Czarnecka J, Kowalczyk A, Barszcz K, Bernas T, Piwocka K, Kaminska B. (2017) Some chemotherapeutics-treated colon cancer cells display a specific phenotype being a combination of stem-like and senescent cell features. Cancer Biol Ther. 20:0. doi: 10.1080/15384047.2017.1385675. [ PubMed ]

Przanowski P, Loska S, Cysewski D, Dabrowski M, Kaminska B. (2017) ISG'ylation increases stability of numerous proteins including Stat1, which prevents premature termination of immune response in LPS-stimulated microglia. Neurochem Int. doi: 10.1016/j.neuint.2017.07.013. [ PubMed ]

Mattei D, Ivanov A, Ferrai C, Jordan P, Guneykaya D, Buonfiglioli A, Schaafsma W, Przanowski P, Deuther-Conrad W, Brust P, Hesse S, Patt M, Sabri O, Ross TL, Eggen BJL, Boddeke EWGM, Kaminska B, Beule D, Pombo A, Kettenmann H, Wolf SA. (2017) Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment. Transl Psychiatry. 7(5):e1120. [ Pub Med ]

Gieryng, A., Pszczolkowska, D., Walentynowicz, K.A., Rajan, W.D., Kaminska, B. (2017) Immune microenvironment of gliomas. Lab. Invest. 97(5):498-518. [ PubMed ]

Kijewska M., Kocyk M., Kloss M., Stepniak K., Korwek Z., Polakowska R., Dabrowski M., Gieryng A., Wojtas B., Ciechomska I.A., Kaminska B. (2017) The embryonic type of SPP1 transcriptional regulation is re-activated in glioblastoma. Oncotarget [Ahead of print] doi: 10.18632/oncotarget.14092. [ PubMed ]

Ellert-Miklaszewska A, Poleszak K, Kaminska B. (2017) Short peptides interfering with signaling pathways as new therapeutic tools for cancer treatment. Future Med Chem [Ahead of print] doi: 10.4155/fmc-2016-0189. [ PudMed ]


2016

Ellert-Miklaszewska, A., Dallavalle, S., Musso, L. , Martinet, N., Wojnicki, K. and Kaminska, B. (2016) Identification of new scaffolds with anti-tumor action toward human glioblastoma cells. Med Chem Commun,7, 2428-2434. [ Link ]

Gieryng, A., Kaminska, B (2016) Myeloid-derived suppressor cells in gliomas. Contemporary Oncology 20(5): 345-351. [ Link ]

Klionsky D.J., Abdelmohsen K., Abe A., (...), Ciechomska I.A., et al. (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12:1-222. [ PubMed ]

Was H., Barszcz K., Czarnecka J., Kowalczyk A., Bernas T., Uzarowska E., Koza P., Klejman A., Piwocka K., Kaminska B., Sikora E. (2016) Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice. Oncotarget 8:9303-9322 doi: 10.18632/oncotarget.14066. [ PubMed ]

Ciechomska I.A., Przanowski P., Jackl J., Wojtas B., Kaminska B. (2016) BIX01294, an inhibitor of histone methyltransferase, induces autophagy-dependent differentiation of glioma stem-like cells. Scientific Repors 6:38723. [ PubMed ]

Ellert-Miklaszewska A, Wisniewski P, Kijewska M, Gajdanowicz P, Pszczolkowska D, Przanowski P, Dabrowski M, Maleszewska M, Kaminska B. (2016) Tumor-processed osteopontin and lactadherin drive the pro-tumorigenic polarization of microglia and glioma progression. Oncogene 35:6366-6377. [ PubMed ]

Torabi Moghadam, B., Dabrowski, M., Kaminska, B., Grabherr, M.G., Komorowski, J. (2016) Combinatorial identification of DNA methylation patterns over age in the human brain. BMC Bioinformatics 17(1):39. [ PubMed ]

Kaminska B., Mota M., Pizzi M. (2016) Signal transduction and epigenetic mechanisms in the control of microglia activation during neuroinflammation. Biochimica et Biophysica Acta, 1862(3):339-51. [ PubMed ]

Stokowy T., Wojtas B., Jarzab B., et al. (2016) Two-miRNA classifiers differentiate mutation-negative follicular thyroid carcinomas and follicular thyroid adenomas in fine needle aspirations with high specificity. Endocrine, 54:440-447. [ PubMed ]

Stokowy T., Gawel D., Wojtas B. (2016) Differences in miRNA and mRNA Profile of Papillary Thyroid Cancer Variants. International Journal of Endocrinology, 2016:1427042. [ PubMed ]


2015

Mieczkowski J., Kocyk M., Nauman P. et al. (2015) Down-regulation of IKKβ expression in glioma-infiltrating microglia/macrophages is associated with defective inflammatory/immune gene responses in glioblastoma. Oncotarget, 6: 33077-33090. [ PubMed ]

Maleszewska M., Kaminska B. (2015) Deregulation of histone-modifying enzymes and chromatin structure modifiers contributes to glioma development. Future Oncology, 11:2587-2601. [ PubMed ]


2014

Przanowski P., Dabrowski M., Ellert-Miklaszewska A. et al. (2014) The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia. Journal of Molecular Medicine, 92: 239-254. [ PubMed ]

Kruczyk M., Przanowski P., Dabrowski M. et al. (2014) Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells. Biochimica et Biophysica Acta, 1839:1341-1350. [ PubMed ]


2013 and earlier

Sielska M., Przanowski P., Wylot B. et al. (2013) Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response. Journal of Pathology, 230: 310-321. [ PubMed ]

Ellert-Miklaszewska A., Dabrowski M., Lipko M. et al. (2013) Molecular definition of the pro-tumorigenic phenotype of glioma-activated microglia. Glia, 61:1178-1190. [ PubMed ]

Ciechomska I.A. Gabrusiewicz K., Szczepankiewicz A.A., Kaminska B. (2013) Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine A-induced cell death. Oncogene, 32: 1518-29. [ PubMed ]

Światek-Machado K., Mieczkowski J., Ellert-Miklaszewska A. et al. (2012) Novel small molecular inhibitors disrupt the JAK/STAT3 and FAKsignaling pathways and exhibit a potent antitumor activity in glioma cells. Cancer Biology & Therapy, 13: 657-670. [ PubMed ]

Gabrusiewicz K., Ellert-Miklaszewska A., Lipko M. et al. (2011) Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas. PLOS ONE, 6:e23902. [ PubMed ]

Kwiatkowska A., Kijewska M., Lipko M. et al. (2011) Down-regulation of Akt and FAK phosphorylation reduces invasion of glioblastoma cells by impairment of MT1-MMP shuttling to lamellipodia and down-regulates MMPs expression. Biochimica et Biophysica Acta, 1813: 655-667. [ PubMed ]

Tyburczy M.E., Kotulska K., Pokarowski P. et al. (2010) Novel proteins regulated by mTOR in subependymal giant cell astrocytomas of Patients with Tuberous Sclerosis Complex and new therapeutic implications. American Journal of Pathology, 176: 1878-1890. [ PubMed ]


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