Biosystems Simulation Lab
朱智瑋老師研究室—The Research Group of Professor Jhih-Wei Chu
The Chu Research group
The Chu Research group
My research group develops computational methods and applies them to simulate biosystems from the molecular scale up. The goal is to elucidate how biological functions emerge from the behaviors of building blocks and their spatial and temporal arrangement. To pursue this endeavor, we take a multiscale approach to integrate modeling with experiment and bioinfomatics. We also aim to apply this unique methodology to trace the origin of diseases, discover new therapeutics, and develop bio-inspired engineering systems. Currently we are interested in the protein dynamics, conformational changes, and reaction mechanism of nucleases in DNA repair, immunity regulation, and genotoxicity remediation.
My research group develops computational methods and applies them to simulate biosystems from the molecular scale up. The goal is to elucidate how biological functions emerge from the behaviors of building blocks and their spatial and temporal arrangement. To pursue this endeavor, we take a multiscale approach to integrate modeling with experiment and bioinfomatics. We also aim to apply this unique methodology to trace the origin of diseases, discover new therapeutics, and develop bio-inspired engineering systems. Currently we are interested in the protein dynamics, conformational changes, and reaction mechanism of nucleases in DNA repair, immunity regulation, and genotoxicity remediation.
本研究室使用計算方法對生物系統進行模擬．其目的在瞭解系統元件的行為以及元件組成架構與生物功能之關係．為此，我們發展多層級模擬方式以整合實驗與生物資訊．本組也致力於利用我們獨特的計算模擬架構在疾病探源、新藥發現及建構仿生系統等課題作出貢獻．
本研究室使用計算方法對生物系統進行模擬．其目的在瞭解系統元件的行為以及元件組成架構與生物功能之關係．為此，我們發展多層級模擬方式以整合實驗與生物資訊．本組也致力於利用我們獨特的計算模擬架構在疾病探源、新藥發現及建構仿生系統等課題作出貢獻．