Biosystems Simulation Lab

朱智瑋老師研究室The Research Group of Professor Jhih-Wei Chu

The Chu Research group

My research group develops computational methods and applies them to simulate biosystems from the molecular scale up. The goal is to elucidate how biological functions emerge from the behaviors of building blocks and their spatial and temporal arrangement. To pursue this endeavor, we take a multiscale approach to integrate modeling with experiment and bioinfomatics. We also aim to apply this unique methodology to trace the origin of diseases, discover new therapeutics, and develop bio-inspired engineering systems. Currently we are interested in the protein dynamics, conformational changes, and reaction mechanism of nucleases in DNA repair, immunity regulation, and genotoxicity remediation.