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Gastrointestinal symptoms are the most common side effects during OIT. Although they are generally mild and self-limited, GI side effects can be more problematic during food allergen desensitization if bowel habits are irregular at baseline. Constipation, in particular, can result in abdominal pain that can be difficult to differentiate from dose-associated discomfort during OIT. Teach your child that bodily functions are not shameful. If your child is old enough to handle all toileting independently, have a discussion about frequency and consistency of stools. We need hydration, fiber intake, and physical activity to keep the bowels moving. Some doctors also believe taking a probiotic during OIT can help keep the gut microbiome balanced and promote regularity. However, a more proactive approach is sometimes needed. Discuss with your pediatrician, gastroenterologist, or allergist if bowel irregularity or baseline abdominal discomfort are concerns.

Additionally, maintain a diet with a balance of lean protein, fresh produce, complex carbohydrates, and healthy fats. Having healthy food in the belly before dosing is essential to reduce to chances of experiencing pain, nausea, or vomiting after dosing.

For a more detailed explanation of the risks and benefits of OIT, please refer to Dr. Bajowala’s book, “The Food Allergy Fix: An Integrative and Evidence-Based Approach to Food Allergen Desensitization”.