Droplets and Condensates in Biological Systems
CSIR-IGIB, South Campus
11th Dec, 2023
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Phase separated subcellular structures such as lipid droplets and condensates have been known for decades, yet their functions, mechanisms of formation and resolution, composition and regulation has only recently begun to be appreciated in biological phenomena. The relevance of these phase separated structures is now being understood in the context of metabolism, proteostasis, and gene regulation. This emerging field is impacting our understanding of neurodegenerative diseases, metabolic diseases, and infectious diseases. This one-day symposium will bring together researchers actively working across these fields, at CSIR-Institute of Genomics and Integrative Biology, to talk about their research in this area.
Phase separated subcellular structures such as lipid droplets and condensates have been known for decades, yet their functions, mechanisms of formation and resolution, composition and regulation has only recently begun to be appreciated in biological phenomena. The relevance of these phase separated structures is now being understood in the context of metabolism, proteostasis, and gene regulation. This emerging field is impacting our understanding of neurodegenerative diseases, metabolic diseases, and infectious diseases. This one-day symposium will bring together researchers actively working across these fields, at CSIR-Institute of Genomics and Integrative Biology, to talk about their research in this area.
Speakers
Speakers
Roop Mallik
Indian Institute of Technology, Bombay
Samrat Mukhopadhyay
IISER, Mohali
Shovamayee Maharana
IISc, Bangalore
Shravanti Rampalli
CSIR-IGIB, New Delhi
Abdou Rachid Thiam
Ecole Normal Superiere, Paris
Zoher Gueroui
Ecole Normal Superiere, Paris
Francesca Di Nunzio
Institut Pasteur, Paris
Sheetal Gandotra
CSIR-IGIB, New Delhi
Registration closes on 20th November, 2023
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Program Details
9:20-9:25 Welcome address: Director IGIB
9:25-9:30 Opening remarks Sheetal Gandotra
9:30-10:05 Roop Malik, Targeting Kinesin on Monolayer Membranes : Implications to Lipid Homeostasis
10:05-10:40 Sheetal Gandotra, Lipid droplet turnover: lessons from a professional phagocyte
10:40-11:15 Samrat Mukhopadhyay, A Deep Dive into Biomolecular Condensates
11:15-11:45 Tea/Coffee Break
11:45-12:20 Shovamayee Maharana, RNA-RBP condensates sense cellular RNA and buffer immune response
12:30- 14:00 Lunch
14:00-14:35 Abdou Rachid Thiam (online), From the biophysics to the cell biology of lipid droplets
14:40-15:15 Zoher Gueroui (online), Engineering phase separations in cells to manipulate biomolecular condensates
15:20-15:50 Tea/Coffee Break
15:50-16:25 Francesca Di-Nunzio (online), HIV and nuclear biomolecular condensates
16:30-17:10 Shravanti Rampalli, Modulation of Viral Biomolecular Condensates by lysine methylation
17:10-17:15 Closing remarks
Organizer: Sheetal Gandotra
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