GENOMICS & BIOLOGY OF NEUROLOGICAL DISEASES
Our laboratory is interested in elucidating the pathogenic mechanisms underlying neurological disorders that impact movement, learning and memory. We are taking a multidisciplinary approach to investigate the molecular, cellular and circuitry changes that form the basis of neurodegenerative disorders to develop strategies to delay or prevent the death of neurons.
Our laboratory is interested in elucidating the pathogenic mechanisms underlying neurological disorders that impact movement, learning and memory. We are taking a multidisciplinary approach to investigate the molecular, cellular and circuitry changes that form the basis of neurodegenerative disorders to develop strategies to delay or prevent the death of neurons.
iCROWD - Indian Collaborative Research Network on Wilson's Disease
iCROWD - Indian Collaborative Research Network on Wilson's Disease
The iCROWD consortium aims at using cutting edge genomics technology to enable identification of genetic variations in diseases and help clinicians arrive at a precise diagnosis for rare genetic diseases.BK Lab is part of the GUaRDIAN consortium which comprises of over 150 clinicians and researchers more
The iCROWD consortium aims at using cutting edge genomics technology to enable identification of genetic variations in diseases and help clinicians arrive at a precise diagnosis for rare genetic diseases.BK Lab is part of the GUaRDIAN consortium which comprises of over 150 clinicians and researchers more
Cognition and synaptic plasticity in diabetes mellitus
Cognition and synaptic plasticity in diabetes mellitus
Alzheimer's disease (AD) and Type 2 diabetes mellitus (T2D) are both age-related disorders, and their prevalence is rising globally. Cyclin-dependent kinase 5 (CDK5) is a pivotal regulator of neuronal signal transduction and its activator p35 is predominantly present in neurons and pancreas. Cdk5 can be a potent link between T2D and cognitive impairment as this kinase plays a critical role in both disease types. We are, therefore, interested in understanding the specific neural circuits and/or molecular pathways that are primarily targeted in Type 2 Diabetes related neurodegeneration and how they can be restored. Currently, we are evaluating whether CDK5 plays a role in cognition and synaptic plasticity in diabetes mellitus.
Join The Lab
If you are passionate about scientific research and innovation, motivated, ambitious and driven; The BK Lab is always looking for motivated graduate students, and postdocs to join the lab. We are a community of open minded and scientifically curious folks - if that sounds like you and you are interested in joining our community, ​Please e-mail me or other current members.Join The Lab