COVID-19 Pandemic : Emails from 2021 FOIA request of Dr. Anthony Fauci (8)
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------ CbH6J>Je; rnigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject : Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, asglobal infections rise(b) (5)Sound good?From: Fauci, Anthony (NIH/N IAID) [E] (b)( >Sent : Saturday, February 22, 2020 3:12:02 PMTo: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD)(b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)> _____ _,Subject : FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days,as global infec tion s riseNIH-001620Folks:TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301) 496-4409E-mail (b) (6)The information in this e-ma il and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Folkers, Greg (NIH/ NIAID) [E) --------- (b)(6) Sent : Saturda y, February 22, 2020 10:52 AMSubject : Wpost: New developments suggest coronavi rus incubation could be longer than 14 days, asglobal infections riseNew developments suggest coronavirusincubation could be longer than 14 days, asglobal infections riseNIH-001621(b) (5)Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium inWuhan in central China's Hubei province. (AP)ByAnna Fifield,Min Joo Kim andSimon DenyerFeb. 22, 2020 at 10:17 a.m. ESTThere are new indications that the incubation period for the virus could be longer than the currentlybelieved 14 days, with patients testing positive after much longer quarantine periods. This developmentcame as infections rose in South Korea, Japan, Iran and It aly and the head of the World HealthOrganization warned that the window for stopping the epidemic was narrowing .Here's what we know:• Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><."• South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases inSouth Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50confirmed cases, making it the largest hot spot in Europe.• China reported only 397 new cases Saturday, as the rate of increase continued to decline, but anaddit ional 109 people have died. There continues to be a great deal of skepticism about China'snumbers as t he criteria for diagnosing coronavirus keep changing.• A team of international epidemic experts had Wuhan added to their itinerary in China, followingquestions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused morethan 2,000 deaths in the country .• Scientists in China said they had isolated coronavirus strains in urine, raising the possibility that itmight be transmissible that way, as well as through fecal matter and respiratory droplets .NIH-001622NIH-001623BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longerthan the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria forcontain ing the virus amid an increasingly urgent effort to stop the epidemic from spreading in northeastAsia and across the world.South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said thecountry was seeing a sudden rise in coronav irus cases, with roughly 50 confi rmed in the past two days- an outb reak that represents the largest yet across Europe.Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine.A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, theepicente r of the coronaviru s outbreak.WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining thespread of the coronavirus, after cases were reported earlier in Iran and Lebanon."Although the window of opportun ity is narrowing to conta in the outbreak , we still have a chance tocontain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there will bea serious problem on our hands."Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat thesituation in the city and in surround ing Hubei prov ince "rema ins grim and complex," according to areport by the official Xinhua News Agency published Saturday."The nationw ide inflect ion point of the epidemic has not yet arrived," the report said after a meeting ofCommunist Party leaders.China' s National Health Commission reported Saturday that 397 new cases of coronav irus had beendiagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears tohave slowed markedly, although there has been a great deal of conf usion about the statistics th is weekas officials have repeatedly changed the crite ria for confi rming cases.Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed asinfected after 27 days in isolation, while a man in Jiangxi province tested posit ive after 14 days ofentralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a manin Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period withno symptoms.Coronavirus cases in South Korea skyrocket; cases triple in JapanIn Seoul, the Korea Centers for Disease Control and Prevention reported Saturday that 229 addit ionalcases of the coronav irus had been detected, taking the tota l to 433, more than doubling in the space ofa day. This makes it the worst -affected count ry outs ide China."Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, andwe're work ing closely with the government to f ully understand the transmission dynamics that led toth is increase," Tedros said.The majority of the new cases have been traced to existing clusters at a church in southern city of Daeguand a hospital in nearby Cheongdo County, according to the KCDC.The South Korean government has designated Daegu and surrounding North Gyeongsang province as"special care zones" where conta inment efforts and support will be concentrated.More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesusthe Temple of the Tabernacle of the Testimony .Since members of the church attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronaviruscases have been reported the re, includ ing two patients who died from the virus.NIH-001624The mass infection at the hospital is centered on its locked psychiatric ward, where a confinedenvironment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC.A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infectedwith the virus. He is the third person to die from the virus in South Korea.Trump was not told coronavirus-infected Americans would be flown home from cruise shipIn Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. Thatnumber excludes the 634 people on board the Diamond Princess who contracted the virus.One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, whocomplained of nausea whi le working. The mayor of Chiba city said the school will be closed untilWednesday, public broadcaster NHK reported.The teacher had not traveled abroad in the past two weeks and has no record of having been in contactwith a known infected person, underl ining the fact that the virus is now spreading almost invisiblythroughout the country, experts say.Quarantines in effect in parts of Italy amid sudden spike in casesAs numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, askingsome 50,000 people to stay indoors and suspending all public events - including religious ceremoniesand school - in 10 small towns to the south of Milan.Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists."There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northernLombardy region, which has seen the majority of the cases.Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday saidthat a 77-year-old woman had also tested positive for the virus after being found dead in her home. ButItalian authorities said the woman suffered from other health conditions, and were unsure if it was thevirus that had killed her.As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, whichincludes the country's financial hub, Milan . There were another 12 cases in the neighboring northernregion of Veneto.The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus isjumping from one place to the next."It goes to show you that having other cases of contagion is absolutely possible," Zaia said.According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearoldwho'd had dinner with somebody who had j ust come back from China. But some three weeks passedbetween that dinner and the time the man came down with a fever. In between, he ran a halfmarathon,played soccer and traveled to several towns, according to La Repubblica, a major Italiandaily .Iran, meanwhile, announced its fifth death from t he virus, raising the country's overall total confirmedcases to twenty eight .Efforts to clear the Diamond Princess cruise ship continueMeanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crewmembers have so far been found to have the virus.All of the passengers have now been tested and almost all have left the ship, either to go home if theytested negative, to local hospitals or government facilities if they have the virus, or back to their homecountries.Some passengers were asked to stay on board to serve an additional quarantine if their cabin matecontracted the virus, but this group is also disembarking Saturday to serve out the rest of theirquarantine in a government facility, local media reported .In China's 'war' on coronavirus. hospita ls turn away ot her pat ients - with dire resultsNIH-001625More than 200 port calls in Japan by international cruise ships have been canceled since the beginningof February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lostrevenue from passengers coming ashore dealing another blow to Japan's weak economy .Controversy continues to simmer about the infection control procedures on board the ship, after adoctor complained on Tuesday about "chaotic" and scary conditions on board .Six people working on the boat or with the passengers, including four government officials, a medic andan ambulance driver, have contracted the virus.Media reports questioned why about 90 government officials who worked on the ship have returned towork without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato saidthe government is "trying to confirm what operations staff were involved in specifically."Amer ican woman in Malays ia declared free of coronavirusThe 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpurairport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysiahealth authorities said Saturday.The woman "is showing good improvement and signs of recovery, however, she is still being monitoredand managed in hospital for a slight cough," Malaysia's director general of health, Noor HishamAbdullah, said in a st atement.The woman repeatedly tested negative while on board the ship and when she disembarked inSihanoukville, then twice tested positive while transiting in Kuala Lumpur airport on Feb. 15. That set offa global scramble to track the hundreds of other passengers who had also disembarked then boardedplanes bound for home.The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and sheshowed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted24 hours apart, both came back negative for coronavirus.But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was everinfected, saying she "never had coronavirus to our knowledge .""I have confirmed that all the passengers were tested, and they have come back negative forcoronavirus, including the person who initially tested positive ," USA Today quoted CDC spokespersonRichard Quartarone as saying. The woman " may have had a respiratory illness, but if she did, it was notcovid-19," he said, using the official name for the virus.Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on boardthe Westerdam and the 781 passengers who were still in the country of coronavirus infection .Chinese scientists isolate coronavirus strains in urine as WHO prepares visitSeparately, scientists in China are continuing to study how the virus is transmitted .A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irusstrains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State KeyLaboratory, told reporters in Guangdong on Saturday.The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets,appeared to be transmissible through fecal matter, underscoring the need to practice good handwashing as a preventive measure.Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strainshad been isolated and that this had implications for public health control. They are cont inuing to workon isolating the virus and on a cure, the Guangzhou Daily reported.But he said people should pay more attention to personal and family hygiene to prevent the spread ofthe virus and recommended frequently washing hands, closing the toilet lid before flushing and makingsure bathroom drains are not blocked.NIH-001626WHO experts have also been on an investigative mission in China this week, holding meetings in Beijingand traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel toWuhan, where the outbreak began at a live animal market and which remains under strict lockdown inan effort to contain the virus.This had led to speculation that the Chinese government, which has come under fire for its slowresponse to the outbreak and where medical workers are stretched to the limit, did not want theexperts to visit.But the WHO said late Friday that the experts would be travel ing to the center of the outbreak onSaturday, although they gave no further information about their itinerary .Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and ChicoHarlan and Stefano Pitrelli in Rome contributed reporting.Two Beijing hospit als quarantine d amid fears coronav irus infect ions will spike in t he capita lConfusion mounts over China' s count ing met hods as coronav irus numbers swing wildlyCoronavirus claims lives of two passengers from Diamond Princess cruise ship, Japanese media saysToday1s coverage from Post corr espondents around t he worldLike Washingt on Post World on Facebook and stay updat ed on fo reign newsDisclaimer : Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily representmy views nor those ofNIATD, NTH, HHS, or the U.S. government.From:Sent :Fauci, Anthony (NIH/NIAIO) [ElSat, 22 Feb 2020 18:35:29 +0000To:Subject:Mermin, Jonathan (CDC/DDID/NCHHSTP/OD)RE: COVID-19Jono:Many thanks for your kind note. Much appreciated. I hope th at all is we ll withyo u.Best regards,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone Cb) (6)FAX: (301 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) ------ CbH > Sent : Saturday, February 22, 2020 1:14 PM ------=--c= To: Fauci, Anthony (NIH/NIAID) [El CbH6)>Subject: COVIO-19Tony:I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstandingwork .Best,JonoNIH-001651From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Fri, 21 Feb 202011:59:09 +0000To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, RachelBarwick (CDC/0D1D/NCEZID/DGMQ)Subject: RE: Infectious disease advice for NSO Asia tourThanks, Marty.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6lThe information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) ------(b)( > Se nt : Friday, February 21, 2020 6:31 AM -------= = To: Fauci, Anthony (NIH/NIAID) [E] --------- (b)( ; Collins, Francis (NIH/OD) [El (b )(Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS)------ (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSO Asia tourTony and FrancisHappy to be a POC fo r Deborah . She can text me (b)(6)and we can arrange a time to speak. Mycell recept ion in EOC not great. Alternative ly EOC can track me down (b)(6)Email pretty clogged these days ...Best,MSCGet Out look for iOSFrom: Fauci, Anthony (NIH/N IAID) [El -------- CbH > Se nt: Friday, February 21, 2020 5:46:50 AMTo: Collins, Francis (NIH/OD) [E] -------- (b)(6)NIH-001694Cc:C etron, Marty (CDC/DDID/NCEZID/DGMQ)_ ___(b)( ._..>..; C onrad, Patricia (NIH/NIA ID) [E](b)(6)Subject: RE: Infectious disease advice for NSO Asia tourFrancis:(b)(5)------------- (b) (5) The best person in the wor ld for this is Marty Cetron at the CDC. am copying him on this e-mail. Perhaps he can direc tly get back to you.Best,Tony-----Original Message-----From: Collins, Francis (NIH/OD) [E] -------- (b)(6)Sent: Friday, February 21, 2020 5:21 AM -------=-:-:= To: Fauci, Anthony (NIH/NIAID) [El- -------- (b)(6) Subject: FW: Infectious disease advice for NSO Asia tourHi Tony,See below from Deborah Rutter, the head of the Kennedy Center .Who would you recommend at NIH or CDC to be a contact?Francis-----Original Message-----From: Rutter, Deborah F.<DFRutter@Kennedy-Center .org>Sent: Thursday, February 20, 2020 5:59 PMTo: Collins, Francis (NIH/OD) [El (b)( >Cc: Ginstling, Gary <GGinstling@Kennedy-Center .org>Subject: Infectious disease advice for NSO Asia tourDear Francis(b) (5) ------------As you may know, the National Symphony Orchestra has long had an Asia your on its schedule for Marchthis year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks agobut the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of themembers and our management are looking for addit ional advice on travel concerns and any infectiousdisease warning/direction. Would you have someone amongst your brilliant colleagues who could be aresource to our team?I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you somuch for any direction you can offer us!DeborahNIH-001695NIH-001696This e-mail message is intended only for the recipient(s) named above. This message may contain tradesecrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission, dissemination, reproduction or other use of, or taking of any action in reliance upon, thisinformation by persons or entities other than the intended recipient is prohibited. If you received this inerror , please contact the Sender and delete the material from any computer .From:Sent:To:(b)(6)Tue, 18 Feb 2020 15:41:35 -0500Conrad, Patricia (NIH/NIAID) [E)Subject: Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 MarchLet us discuss.Begin forwarded message:From: "Wolfe , Mitchell (CDC/OD)" ------- (b)(6) Date: February 18, 2020 at l :08:55 PM ESTTo: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~Cc: "Conrad, Patricia (NIH/NIAID) [E]"(b)(Subject: F,v: Lunch with AMB at Thai Residence on 27 Feb or 4 MarchTony,The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4March. They didn't have your contact and asked (per below) if I could contact you toask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If youor your staff can let me know, I will get back with them.Best regards,Mitchell Wolfe, MD, MPHRADM, USPHSChief Medical Officer, Office of the DirectorCenters for Disease Control and PreventionPh:- ----(b)(6)From: Panupat Chavananikul <panupatc@thaiembdc.org>Sent: Tuesday, February 18, 2020 12:42 PMTo: Wolfe, Mitchell (CDC/OD) (b)(6)Cc: Chuliepote lsarankura Na Ayudhaya <chuliepotei@thaiembdc .org>Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 MarchDear P Mitch krub,Ref: invita t ion for Lunch on 27 Feb OR 4 March1. Hope all is well with you. Hopefully you had some rest last weekend. Since you wereliving in Thailand for a while you must be missing authentic Thai food . Ambassador ThaniNIH-001780wiould like to extend his invitation to you and CDC colleagues to have lunch at Thairesidence either on Thursday 27 Feb or Wednesday 4 March at 12.30 pm. His residencelocated at (b)(6) You may invite your colleagues who involve inCoronavirus or Thailand, and please let me know their name and ranking as well as youravailable date.For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some ofour colleagues.2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC,on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci alsoreceived Prince Mahido l award back in 2013 . Ambassador would also like to have him joinour lunch at his residence as well.Is it possible that you may reach out to him to see whether he can have lunch with us ornot, OR you may provide me his contact detai ls.Thank you krub &Best wishes,Panupat (boat)Mr .Panupat ChavananikulCounsellor (Consul)Royal Thai EmbassyCell Cb) (6)Work 202 640-5308NIH-001781From:Sent :To:Fauci, Anthony (NIH/NIAI0) [E)Tue, 18 Feb 2020 14:57:27 +0000Redfield, Robert R. (CDC/OD)Subject :Attachments :RE: Severity Assessment for U.S. Response - CDCSeverity Assessment for U.S. Response - CDC.docxBob:See my minor tra cked edits.Thanks,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who Is not the original Intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From : Redfield, Robert R. (CDC/OD) (b) (6)Sent : Tuesday, February 18, 2020 9:35 AMTo: Fauci, Anthony (NIH/NIAID) [E)_ _____ _,(_b_ )- ,(-6=)Subject : Fwd: Severity Assessment for U.S. Response - CDCTake a look ?edits thoughtsOr. Robert RedfieldFrom : Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6)Sent: Monday, February 17, 2020 10:48:48 PMTo: Redfield, Robert R. (CDC/OD) (b)(6)Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ)------ CbH6J>B;u tler, Jay C. (CDC/DDID/O0) CbH6J> Subject : Severity Assessment for U.S. Response - CDCDr. Redfield:Here is the severity assessment in response to your request from yesterday. Take a look and see if thisaddresses your request.DanNIH-001784From:Sent:Fauci, Anthony (NIH/NIAID) [E)Wed, 19 Feb 2020 12:03:04 +0000To: Marks, Peter;Schuchat, Anne MD (CDC/OD)Cc: Cho, David S (CBER) (FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston,Hilary (NIH/NIAID) [E]Subject: RE: Covid-19 Survival on SurfacesPeter:Vincent Munster at NIAi D's RML has done work on thi s. I am copying him onthis e-mail.Best,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Marks, Peter Cb) ( >Sent: Wednesday, February 19, 2020 6:41 AMTo: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E](b)(6)Cc: Cho, David S (CBER)( FDA/CBER)- -------- (b)(6) Subject: Covid-19 Survival on SurfacesDear Anne and Tony,I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDC who iswork ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on variousproducts and other perishab le items. The food safety people here at FDA are quite concerned about thelatter, given published reports of differential coronavirus surv ival on various surfaces.If it turns out that this has not been evaluated, or is not in the process of being evaluated, we are happyto work on this in our BSL-3 labs, which are now in receipt of the v irus.NIH-001763NIH-001764Thanks so much for any direction that you can provide.Best Regards,PeterFrom: Fauci, Anthony (NIH/NIAID) [E)Sent : Sat, 15 Feb 2020 12:55:47 +0000To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman,Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [ElCc: Holland, Steven (NIH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen(NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [ElSubject: RE: COVID-19 messaging(b) (5)From: Gilman , James (NIH/CC/OD) [El (b)(6)Sent: Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El(b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara"(:N"":"l.~H"./-' :0-::-D:-~:) "[:E"~]: ====~__,_., (b).,.(.6=; ) >; Fauci, Anthony (NIH/N IAID) [E] CbH >Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>J; ohnson, Alfred (NIH/OD) [E](b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Cb)( ; Schmitt,James (NIH/OD/ORS) [El (b)(6)Subject: Re: COVID-19 messaging(b) (5)JimFrom: "Collins, Francis (NIH/OD) [El" CbH6J>Date : Friday, February 14, 2020 at 8:04:30 PMTo: "Gottesman , Michael (NIH/OD) [E)"--------aa- Cb~H=6J>, "Tabak, Lawrence (NIH/OD) [E]"(b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (b)( >, "Fauci, Anthony---:----:-~~==:::!....:--~~(NIH/NIAID) [El" Cb)( >Cc: "Holland, Steven (NIH/NIAID) [El" (b)( >, "Johnson, Alfred (NIH/OD) [El"---------- (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) ,11 Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El"(b)(6)>Subject: RE: COVID-19 messaging1111Lo oping in Jim Gilman .FCFrom: Gottesman, Michael (NIH/OD) [E]Sent : Friday, February 14, 2020 6:03 PM(b)(6)>NIH-001869To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El--.--.~~==:!:...,_(b_)( 6); C_o lli_ns_, _F;r~an~c is (NIH/OD) [El (b)(6)>; Fauci, Anthony(NIH/NIAID) [El (b)(6)>Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E](b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt,James (NIH/OD/ORS) [El CbH6J>Subject : COVID-19 messagingWe have had many requests for additional guidance concerning staff potentially exposed to COVID-19.OMS has prepared the attached message which has been reviewed by Steve Holland and HR.The intent is to send t his from OMS to all hands.MichaelNIH-001870From:Sent :To:Subject :Attachments :Fauci, Anthony (NIH/NIAIO) [E)Sat, 15 Feb 2020 02:23:37 +0000Holland, Steven (NIH/NIAID) [E]RE: COVID-19 messagingCOVID-smh - with Fauci edits .docxSteve:See m',' tracked edits.Thanks,TonyFrom: Holland, Steven (NIH/NIAID) [E]- -------- (b) (6)> Sent: Friday, February 14, 2020 9:06 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [E] ______ Cb><_ >Subject : FW: COVID-19 messagingTony,Could you please look at the attached and make any edits you think would help .SteveDirector , Division of Intramural ResearchNational Institute of Allergy and Infectious DiseasesNational Institutes of HealthBldg. 10/11N248 MSC 1960Bethesda, MD 20892-1960-----(b) (6)voice 301-480-4507 fax----(-b) (6) emailAssistan t lab: Eva Portillo~==~~--- (b)(6) emai l ----(-b) (6) voiceAssistant to SD: Beth SchmidtNIH-001871(b) (5)(b)(5)(b)(5) ~(b)(5)(b)(6)----(b) (6) voiceFrom: "Gottesman, Michael (NIH/OD) [E]" --------- (b)(6 )>Date: Friday, February 14, 2020 at 6:12 PM -------~~ To: "Schmitt, James (NIH/OD/ORS) [E]." .========;:(-b)=(6) -,;:-- Cc: "Moss, Bradley (NIH/OD/ORS) [E)"- -------- (b)(6) Steven Holland (b )( 6)Subject : Re: COVID-19 messaging- · This can wait until next week.MichaelFrom: "Schmitt, James (NIH/OD/ORS) [E]"- -------- (b)(6) Date: Friday, February 14, 2020 at 6:07 PM -------~= To: "Gottesman, Michae l (NIH/OD) [E]" Cb)( >Subject: FW: COVID-19 messagingI meant to copy you on this Michael. JimFrom: Schmitt, James (NIH/OD/ORS) [ElSent: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El- -------- (b)(6)>; Bailin, Heike (b)(6)Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6)(b) (5)----------- (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) [E) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E) (b)(6)>; Tosten, Timothy(NIH/OD/ORS) [E) (b)(6)Subject: FW: COVID-19 messagingHi Bra d,It sounds like Dr. Gottesman wants this sent from OMS to everyone.I don't know how to do that. Can you help us with this and how soon can it be sent?I'm heading out of town and won't retmn to the clin ic until Tuesday . Dr. Bailin will bein charge of OMS in my absence.JimJames M. Schmill, M.D., M.S.Medical DirectorOccupational Medjcal Service, DOHSNIH-001872National In stitutes of Hea lthIO Center DriveBethesda, MD 20892-1584(b)(6)From: Gottesman, Michael (NIH/OD) [E] (b)(6)>Sent : Friday, February 14, 2020 6:03 PM ------- ~= To: Tabak, Lawrence (NIH/OD) (E] (b)( >; Schwetz, Tara {NIH/OD) [E](b)(6); Collins, Francis (NIH/OD) [E) (b)(6)>; Fauci, Anthony7( N- l'H."7'/"N- I"A"l.-'D:"--): -:[-E: -): . ==:::::;.--~ ("b'~=(6)>Cc : Holland, Steven (NIH/NIA ID) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E]--------- (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] (b)( >; Schmitt , James (NIH/OD/ORS ) [E] CbH6)>Subject : COVID-19 messagingWe have had many reques ts for additional guidance concerning staff potentially exposed toCOVID-19. OMS has prepared the attached message which has been reviewed by Steve Hollandand HR.The intent is to send this from OMS to all hands.MichaelNIH-001873From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sat, 15 Feb 2020 02:08:57 +0000To: Cassetti, Cristina (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston,Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [ElSubject: RE: Rapid instrument-free NAAT for COVID-19Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV _NIH.pdfSee attachment as per prior e-mai l.From: Fauci, Anthony (NIH/NIAID) [E)Sent: Friday, February 14, 2020 9:08 PMTo: Gary K. Schoolnik (b)(6)>Cc : Conrad, Patricia (NIH/NIAID) (El (b)(6h ; Barasch, Kimberly (NIH/NIAID) [CJ(b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger,---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E)---------- CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19Gary:Thanks for the note. I would be happy to discuss this with you. Please have your officecontact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient timewhen we can chat.Best regards,TonyFrom: Gary K. Schoolnik (b)(6)>Sent: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)>Cc: Adam de la Zerda (b)(6)Subject : Rapid instrument-free NAATfor COVID-19Dear Tony ,In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer ofVisby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection ofinfectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized,40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; it is used once,and then discarded or recycled . (b)(4)device is stable at room temperature for up to two years and thus it could be deployed widely.NIH-001874NIH-001875We are seriously considering using this platform to develop a rapid test to detect COVID-19.Proof of principles that have been achieved toward that end are our demonstration that thedevice can use two-step RT-PCR to detect influenza A and Bin NP swab samples. The mainfeatures of the device are described in the brief accompanying PDF.I write now because we are unsure, if we were to produce a COVID-19 device, how it would bedeployed, by whom it would be used and who might be willing to purchase it. I would be verygrateful if you might be able to speak briefly with me and my colleagues about these openquestions. I am convinced this device can meet a major unmet need in clinical care and diseasecontrol for this epidemic and we, as a group, want to make a difference. Your advice would beinvaluable as we weigh the risks and benefits of pivoting the company to this application.With all best wishes; I hope all is well with you and your family.garyGary Schoolnik, M.D.Professor of MedicineStanford Medical SchoolAttending Physician (Internal Medicine , Infectious Diseases)Stanford University HospitalChief Medical officerVisby MedicalFrom:Sent:To:(b)(6)Fri, 14 Feb 2020 18:45:53 -0500Julia BelluzSubject: Re: callMy pleasure!On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz <ju lia.belluz@vox.com>wrote :Thank you so much for making the time to comment at what I know is a crushinglybusy time. As usual don't hesitate to ping if you have any fmther comments orquestions! Juliahttps://wwv,,. vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singapore-ussymptoms-pan demicSent from my iPhoneOn Feb 14, 2020, at 1 :21 PM, Fauci, Anthony (NIH/NlAID) [E]Cb()6 ) wrote:Julia:I j ust called you now (7:20 AM Washington, DC time) andgot mvoice mail in German that I could not understand. Youcan call me at CbH6JThanks,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mai l: (b)(6)The information in this e-mail and any of its attachments is confidentialand may contain sensitive Information. It shou ld not be used by anyonewho is not the original intended recipient. If you have received this emailin error please inform the sender and delete it from your mailbox orNIH-001878NIH-001879any other storage devices . The National Institute of Allergy andInfectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender's own and not expressly made on behalf of theNIAID by one of its representatives.From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 21:09:40 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: RE: Your Expertise requested/COVID -19 ForumOK. Let us discuss. As long as it is remote ...Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Conrad, Patricia (NIH/NIAID) [El- ---------(b)(6) Sent: Friday, February 14, 2020 3:45 PMTo: NIAID OD AM <NIAIDODAM@niaid.nih.gov>Subject : FW: Your Expertise requested/COVID -19 ForumPatricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNat ional Institute of Allergy and Infectious DiseasesThe National Inst itutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be usedby anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not acceptliability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives.NIH-001880From: Roache, Christina (b)(6)>Sent: Friday, February 14, 2020 3:38 PM ------~~ TCoc:: CFaouncrai,d A, nPthaotrnicyi a (N(NIHIH/N/NIAIAIDID) ) [[EE]!] -.=-=-=--=-=-=-=(b-)~(6()b =)(6 )> Subject : Your Expertise requested/COVID-19 ForumDear Dr. Fauci,You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l ofPublic Health , and I wanted to see if you were available to participate remotely in a Fomm thatwe are organizing on March 2 about COVID -19.The Forum will live stream on the websites of The World and The Forum, as welJ as onFacebook and YouTube.The World will send a journa list to moderate and co-promot e.The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointlywith The World from PRX & WGBH.Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET onMarch 2; the actual live webcast will be noon-lpm ET.We have been active is cover ing this outbreak . We did a highly successfu l Facebo ok Live Q&Alast week and are doing another Q&A next week.As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4pane lists, plus a moderator. As noted, these discu ssions are live streamed from our LeadershipStudio at our school in front of a stud io audience (about 40 seats) and an online audience.Anyone with an Int ernet connection can watch the live webcasts; no registration or fee isrequired.NIH-001881Previous speakers in The Forum series have included Gina McCarthy , former EPAAdministrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S.Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services;Gordon Brown, former UK Prime Minister ; as well as numerous former governors and keypublic health policymakers and officials from a range of public and private sector entities.The Forum live webcasts are also streamed on The Forum website, where they areaccompanied by a live chat and online commenting, and on Facebook and YouTube. Thesewebcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube andiTunesU channels . We also make available podcasts, transcripts and other materials.Collective ly, the programs and complementary content have resulted in nearly five millionviewer engagements so far, and our website has received visits from more than 200 countries andterritories and every U.S. state.Please share your thoughts when you are able .Cheers,Christina RoacheAssociate Director, Production and Web, The Leadership StudioHarvard T.H. Chan School of Public Health(b)(6)NIH-001882From:Sent :To:Subject :Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 20:23:04 +0000Clayton , Janine (NIH/OD) [ElRE: Sex differences in COVID-19Not much at th is poi nt . ------------------------- (b) (5)Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Clayton, Janine (NIH/OD) [ElSent: Friday, February 14, 2020 3:06 PM(b)( >------ -:-::~ To: Fauci, Anthony (NIH/NIAID) [E]- ------- (b)(6) Subject : Sex differences in COVID-19Hi TonJanineNIH-001883(b) (5)From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 20:21:51 +0000Richard Allen JohnsonSubject: RE: 2020.02. 14 FridayDick:Thanks for the note. I certainly appreciate your concerns about WHO. Notmuch sleep for me lately. Just like internship.Best regards ,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From : Richard Allen Johnson (b)(6) ---------- Sent: Friday, February 14, 2020 3:18 PMTo: Fauci, Anthony (NIH/NIAID) [E) ,------- -(-b,..)_.c=. >; Richard Allen Johnson(b)(6)Subject : 2020.02.14 FridayHi, Tony,I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality oft hose of a thi rd world country . I only hope that they function bette r than their news updates suggest.They need a wo rld class public relations firm.I am deeply concerned re Covid-19 in India (with a population of 1500 million) and Africa (pop ulation100 million). News reports do not mention anything of th is pandemic wait ing to happen.Hope that you are well and gett ing a good night's rest.Best,DickNIH-001884From:Sent :To:Subj ect :Please han dle .Anthony S. Fauci , MDDirectorFauci, Anthony (NIH/NIAIO) [ElFri, 14 Feb 2020 18:27:24 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: inhaled buformin for coronavi rusNational Institute of Allergy and Infectious DiseasesBui lding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301) 496-4409E-mail : (b)(6l(b)(4)The information in this e-m ail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Steven Lehrer (b) (6) > ---------- Sent : Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El -------------- -C-b=H= >; Erbelding, Emily (NIH/NIAID) [E) (b) (6) >Subject : ------ (b)(4) for coronavirusDr. Fauci,(b) (4)Steven Lehrer, MD(b) (4)NIH-001887From: Fauci, Anthony (NIH/NIAIO) [E)Sent: Fri, 14 Feb 202017:39:33 +0000To: Routh, Jennifer (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy(NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E]Subject: RE: for review: proposed responses for Ital ian media requestNice Job. I have made one mino r edit in the fi rst response. Oth erwise, it is readyto go. Thanks.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Routh, Jennifer (NIH/NIAID) [E] (b)( >Sent: Friday, February 14, 2020 12:32 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E)(b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg(NIH/NIAID) [El (b)(6bSubject : for review: proposed responses for Italian media requestDr. Fauci -This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to youdirectly with questions about coronavirus vaccine development. I have drafted proposed responses foryour review attached and pasted below. I will send the final responses to the reporter attributed to you.Coronavirus vaccine: when will it be available? What are the diffi culties?The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in aPhase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine tohealthy adults in the United States to see if it is safe and if it can induce an immune response inrecip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinicaltesting to establish their safety and effectiveness takes t ime. A vaccine against the novel coronavirus willlikely not be widely available for at least a year.NIH-001890Could the Coronavirus mutate, if a vaccine cannot be found in time?We are learning more about the novel coronavirus every day. At this tim e, we are not awar e of anymutations that might affect vaccine development . Based on our exper ience with ot her coronav iruses,including SARS-CoV and MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus willmutate in a way that would have an impact on the development of medical countermeasur es. We areconti nuing to mon ito r this .Will the vaccine be the solution against Coronavirus?A safe and effective vaccine would be an extremely valuable tool to help stop the spread of in fectionand prevent future outbreaks. However, proven public health practices of ident ifying cases, isolatingpatients, and tracing contacts must continue alongside a vaccination program.Thanks,JenJennifer Routh [E]News and Science Writing BranchOffice of Communicatio ns and Government RelationsNational Institute of Allergy and Infectious Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda, MD 20892Direct: (b) ~Di sclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not beused by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. The National Institute of Alle rgy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives.NIH-00189 1From:Sent :To:Fauci, Anthony (NIH/NIAIO) [ElFri, 14 Feb 202017:23:43 +0000Cassetti, Cristina (NIH/NIAID) [E]Subject: FW: (b)( 4)Please han dle. Thanks.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Hardham, John M -----------(b)(6)> Sent : Friday, February 14, 2020 9:15 AM -------::-::-=, To: Fauci, Anthony {NIH/NIAID) [El- ------- (b)((;)> Subject: (b) (4Tony:It was good to see you again at the ASM Biothreats Conference. We had worked together on theMedical Countermeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program(under ASD Andrew Weber) several years ago.If you or your staff have any interest, please feel free to reach out to me.Hope you have a wonderful day !JohnNIH-001892(b) (4)John M. Hardham, Ph.D. I Research Director , Global Biologics ResearchDirector , Zoetis Center for Transboundary and Emerging DiseasesZoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007Office : (b)(6) I Mobile (b)(6) I (b)(6)Visit Us: zoetis .comzgetis Erne ectious DiseasesFORANIMFOAHlRSE . AlJFHO.YR O U. -- First cok now . Fastt om arketNIH-001893From:Sent:To:Cc:(NIH/NIAID) [E]Subject:(b) (4)Nicole:Fauci, Anthony (NIH/ NIAID) [E)Fri, 14 Feb 2020 15:52:49 +0000Strauss, NicoleMascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, PatriciaRE:- --------------------- (b) (4) IThank you for your note and interest. I will copy on this e-mai l Ors. JohnMascola and Barney Graham of our Vaccine Research Center who are developingthe vaccine with Moderna so that they can respond directly to you.Best regards ,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: Cb()6 JFAX : (301 496-4409E-mail : (b)(6JThe information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Strauss, Nicole ---------- (b)(Sent : Friday, February 14, 2020 10:37 AM ------~~ To: Fauci, Anthony .(,;N..I.H__/N;__I A ID). :.[..E.].. :....:..:::===-;:;;::;----(b)(6JCc: Weisser, Karen (b)(6JSubject : _____________________ C_>b_C4_), I ___ C>b_C4_)Dear Dr. Anthony Fauci,(b) (4)NIH-001894Best regards,Nicole• CentreOneNicole StraussPipeline Development & Innovat ion LeadT: (b)(6) I M: (b)(6)500 Arcola Road, Collegeville, PA 19426Website I LinkedlnNIH-001895From: Fauci, Anthony (NIH/NIAIO) [E)Sent :To: (b)(6)Fri, 14 Feb 2020 14:22:00 +0000Greg Folkers ---------- Subj ect : NEJMAttac hment s: NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdfHere it is.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBui lding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sen sitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.NIH-001896From: Fauci, Anthony (NIH/NIAID) [ElFri, 14 Feb 2020 03:20:06 +0000Embry, Alan (NIH/N IAID) [ElConrad, Patricia (NIH/NIAID) [ElSent:To:Cc:Subject: RE: Instit utional request for informationThanks, Alan.From: Embry, Alan (NIH/NIAID ) [E] ______ Cb_H_6)Sent : Thursday, February 13, 20 20 10 :18 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------ (=b)""('6=)>; Fried, Linda P.----------- (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , LeeCb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. ~========-.,;-- (b )( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert"('!N"-'IH- /':N""-IA-1- 0-:)--[:E--): -:::::::=====-_;,_-- ~(b")("=6")'Subject : RE: Institutional request for informationDear Dr. Fried,Answers to your questions are below .1. Is the CDC or NIH overseeing the distrib ution of the live virus in the U.S.?There is an interagency working group convened by the Assistant Secretary for Preparedness andResponse oversee ing samples, and NIH and CDC are central to this . Virus is being deposited in BEiResources (a NIAID contract resource) for characterization, growth and distrib ution. The WA isolateis available now and a Hong Kong isolate may be added soon.2. Will you be the sole source of dist ribution in the U.S., or will institut ions be permitte d to obtain itdirectly from oth er sources?Assuming appropriate permits are in place, there is no limitation on an institution obtaining samplesdirectly from BEi or other sources. In a public health emergency, the U.S. government seeks to makeisolates availab le under a Simple Letter Agreement that does not impose IP restrictions onacademics or developers (see attached language).3. If it can be obt ained from other sources, wh at sources will be permitt ed? For example, the Chinaor Hong Kong CDC or University of Hong Kong?Assuming appropriate permits and safety controls, there is no limitation on from where samples canbe obt ained . However, there may be intellectual property restrictions from some sources and yourtechnology transfer office would need to negotiate if requested directly.4. If you are to be the sole source, w hen would you expect to have a process for consideringrequests?BEi resources already has a process for sharing in place and is currently sharing the vira l isolateobtained from the first Washington case. NIAID ant icipates that other viral isolates will be obtainedsoon, and BEi is committed to making those available to the scientif ic community as soon asNIH-001897possible. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the mainsources for this research resource based on experience with Zika.S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions otherthan the self isolation/quarantine already in place (and of course subject to change over time)?For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For highconsequence viruses, use of proper PPE has been a mitigating factor in quarantine consideration.Please feel free to contact me if you have additional questions.Thanks,AlanAlan Embry, Ph.D.Chief, Respiratory Diseases BranchDivision of Microbiology and Infectious Diseases, NIAID, NIH5601 Fishers Lane, Room 8E31Rockville, MD 20892(b)(6)(b)(6)From: Fauci, Anthony {NIH/NIAID) [E] -------- (b)(6) Sent: Thursday, February 13, 2020 6:35 PMTo: Fried, Linda P. (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6)>Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee(b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ "."--.--.-:--:~==~(.b..):(6..),>_; -M-a~rs=to n , Hilary {NIH/NIAID) [E] CbH6l>E; mbry, Alan(NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] CbH6J>Subject: RE: Institutional request for informationLinda:There is a "sample sharing" working group involving NIH and CDC. I havecopied both Hilary Marston and Alan Embry from NIAID who are involved in thisgroup and will ask them by this e-mail to respond to items #1 through 4.Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province)within previous 14 days, they submit to institutional quarantine ; if in non-Hubeiprovince part of China, then they face self-isolation.Hope that this is helpful.Best regards,TonyNIH-001898Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBui lding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Fried, Linda P. (b)(6)Sent : Thursday, February 13, 2020 12:45 PMTo: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E](b)(6)Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (=b)=(=;.;. =Go=ldman, Lee(b)(6)>; Booth, Jane (b)(6)>; Katznelson, Ira I.======== (;b;:):;:(c6~)Subject : Institutional request for informationDear Ors. Redfield and Fauci,I am writing on behalf of Columbia University, which has received a request from Dr. Ian Lipkin totrans fer live novel coronav irus from Hong Kong to his BSL3 facility at the Univers ity. As we evaluate hisrequest , we note that he has approval from a CDC official to import the virus (see attached). However,as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you:1. Is the CDC or NIH overseeing the distribution of the live virus in the U.S.?2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtainit directly from other sources?3. If it can be obtained from other sources, what sources will be permitted? For example, theChina or Hong Kong CDC or University of Hong Kong?4. If you are to be the sole source, when wou ld you expect to have a process for consideringrequests?5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictionsother than the self isolation/qu arantine already in place (and of course subject to change overt ime)?Thank you ve ry much fo r your help with these important questions as we all try to do our best tocontribute solutions to this health crisis.With best regards,LindaNIH-001899NIH-001900Linda P. Fried, M.D., M.P.H.Dean and Delamar Professor of Public HealthProfessor of EpidemiologyMai lman School of Public HealthProfessor of Medicine, Vagelos College of Physicians and SurgeonsSenior Vice President, Columbia University Irving Medical CenterColumbia UniversityFrom: Fauci, Anthony (NIH/NIAIO) [E)Sent : Fri, 14 Feb 2020 03:00:23 +0000To: Mansoura, Monique K.Cc: Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E)Subject: RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT'sProfessor Andrew LoThanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) andshe can then brief me on it.Best,TonyFrom: Mansoura, Monique K. (b)( '>Sent : Thursday, February 13, 2020 10:36 AMTo: Fauci, Anthony (NIH/NIAID) [E] ----- -- (b,.).(.=6)Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)>Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew LoDr. Fauci,The nation again is fortunate to have your leadership for this latest public health emergency . Thank youfor all you are doing. r know you are extraordinari ly busy, so I'll be brief.I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who hasfocused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1have worked with him to explore financial engineering approaches to estab lish more durable public-privatepartnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Instituteevent this week resonate loudly with Andrew and me.He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tberinformation.Respectfully,MoniqueMON IQUE K. MANSOURA, PH.D., M.B .A .Executive Director, Global Health security and Biotechno logyThe MITRE Corpo ration202 Burl ington Road I Bedford, MA I 01730-1420Office: (b) (6)(b)(6)The MITRE Corporation is a not-for-profit organization that operates federally funded research anddevelopment centers for the United States government.NIH-001901From:Sent :To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 02:56:17 +0000Greg Folkers (b)(6))FW: FYI -- images of SARS-CoV-2 now upLet us make some power point slides from these. Thanks.From: Billet, Courtney (NIH/NIAID) [E) -------- (b) ~ > Se nt: Thursday, February 13, 2020 1:22 PMTo: NIAID OD AM <NIAIDODAM@niaid.nih .gov>Subject: FYI -- images of SARS-CoV-2 now uphttps://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-imageshttps://www.flickr .com/photos/niaid/albums/721 57712 9 14621487NIH-001902From:Sent :To:Cc:Subject:Patty: Let us discuss.Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 02:42:53 +0000Conrad, Patricia (NIH/NIAID) [E)Greg Folkers (b) ( ·)FW: PBS'S FIRING LINE REQUEST// DR. ANTHONY S. FAUCIGreg: Are they a big dea l?From: Melanie Starling <melanie@thedocumentarygroup .com>Se nt: Thursday, February 13, 2020 6:39 PMTo: NIAID NEWS (NIH/N IAID) <NIAIDNEWS@niaid.nih.gov>; Fauci, Anthony (NIH/NIAID) [E)(b)(6)Subject: PBS'S FIRING LINE REQUEST // DR. ANTHONY S. FAUCIImport ance: HighGood Evening,Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER .Due to a last minute cancellation, we are crashing on a deadline and need to know if he is ableto jo in us ASAP.I look forward to hear ing your thoughts and all best ,MelanieMelan ie StarlingFiring Line with Margaret HooverCell: (b)(6)Email: melanie@thedocumen t arygroup .com___. ------- --Fl RI n G LlnEW ith MA RGARET HOOVERGood Evening,NIH-001906NIH-001907This is Melanie Starling writing on behalf of PBS'S FIRING LINE WITH MARGARET HOOVER.FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnestexchange of ideas, with the luxury to let the conversation breathe. Margaret has brought backthe spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today'spolarized cable news ecosystem - at a time when we need it more than ever. One guest. 30minutes. Airing to a thoughtful and engaged PBS audience.We would be honored to have Dr. Anthony S. Fauci join Firing Line for aninterview.Dr. Fauci has dedicated his career to understanding, preventing, and protecting people acrossthe globe from infectious diseases, which is why we would be so honored to share our stagewith him at this time. As the coronavirus continues to spread, we are interested in betterunderstanding the deadly virus the world is racing to contain. Equally, we are interested inhighlighting any other public health issues or policies close to Dr. Fauci's heart. Mostimportantly, with our program, we have the luxury of time-where we can truly delve intothese issues in a substantive, nuanced manner that is missing in much of today's 24-hour newscycle.THE DETAILS FOR TAPINGTAPE DATE: TARGETING FEBRUARY 19TH - EVENING TAPING IS PREFEREDTAPE TIME: 45 MINUTESLOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER)TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST.f lRING LINE is carr ied nationwide on PBS with 99% market pick-up, and is suggestedprogramming for PBS's 8:30 PM ET on Friday nights with multiple airings through the week. OnTwitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBS remains acoveted home for intellectual, elevated programming- and stands out as a top 5 outlet toreach persuadable voters.HIGHLIGHT REELFIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group.Please reach out to me if there is any interest . We will bend over backwards to get it done.Thank you in advance for your consideration, and please feel free to reach out to me 24/7 withquestions or concerns.All the best,MelanieMelanie StarlingFiring Line with Margaret HooverCell: (b)(6)Email: melanie@ t hedocumentarygroup.comABOUT FIRING LINE WITH MARGARET HOOVERFiring Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBSprogram, a smart, civil and engaging contest of ideas. The series maintains the character of theoriginal, providing a platform that is diligent in its commitment to civility and the rigorousexchange of opinion. Firing Line with Margaret Hoover comes at a time when meaningfu ldiscourse is needed more than ever. Interviews and debates will highlight leading lights fromthe left and right, complemented by archiva l footage from the original Firing Line to rem indviewers of longstanding conservat ive and liberal arguments, where they've been disproved orreinforced over time. It is an opportunity to engage in the debate about the America tha t wewant to create for the 21st centu ry - and summon Americans of every politica l persuasion to arigorous examination of the choices we must make together in the challenging years ahead.Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff.ABOUT MARGARET HOOVERMargaret Hoover is an American political commentator . In addition, she is also an author,fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN.HIGHLIGHTS ON FIRING LINE WITH MARGARET HOOVERSpeaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. JohnKasich, Gov. Scott Walker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA),Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, PeterNavarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, AnnCoulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. PramilaJayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, MichaelBloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA)Melanie StarlingPBS's Firing Line with Margaret HooverCell: Cb) (6)Email: melanie@thedocumentaryqroup.com- ---- - FIRlnG LlnENIH-001908From: Fauci, Anthony (NIH/NIAID) [E)Sent: Fri, 14 Feb 2020 02:36:46 +0000To: ncalio@airlines.orgCc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty(C0C/0010/NCEZID/DGMQ)Subject: FW: Coronavirus Task ForceAttachments: Fauci A4A Letter to Coronavirus Task Force .pdfNick:Many thanks for sending this. The CDC would be very interested in your willingness to movein the d irection of having complete contact information on passengers available to them. I amcopying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e-mai l. I amsure that one of them will contact you about this issue.Best regards,TonyFrom: Calio, Nicholas <ncalio@airlines.org>Sent: Thursday, February 13, 2020 8:18 PMTo: Fauci, Anthony (NIH/NIAID) [E]--------=- (b):-(-=6: )>Subject: Coronavirus Task ForceDear Dr. Fauci,Please see the attached letter.Thank you,Nick CalioNIH-001909From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 02:09:44 +0000Conrad, Patricia (NIH/NIAID) [ElSubject: RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop)Tell them that I turned down the same invitation and he should turn it down also. It is not amajor eventFrom: Conrad, Patricia (NIH/NIAID) [E]- --------- (b)(6) Sent: Thursday, February 13, 2020 8:21 AMTo: Fauci, Anthony (NIH/NIAID) [El ------~~Cc: Folkers, Greg (NIH/NIAID) [El ,..;.::=======:,;,~ --------- Subject : FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop)Please see below . You were invited to this - it was discussed in our daily meet ingand we decided to decline it for you. we did decline it. would you recommend thesame as they are now asking Dr Collins.Pis advise.Patricia L. ConradPublic Health Analyst andSpec ial Assistant to the DirectorNat ional Institute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaime r:The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be usedby anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not acceptliabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives.From: Harris, Kara (NIH/NIAID) [El -------- (b)(6)>Sent : Wednesday, February 12, 2020 4:18 PM -------~~ To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>Cc: Billet, Courtney (NIH/N IAID) [E)· .=.====~ (b~)~(6)~>-; ~Haskins, Melinda (NIH/NIAID) [E](b)(6)Subject : Invitation : 388393 Santos (Coronavirus Preparedness Workshop)NIH-001910NIH-001911Hi, Patty -Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation tospeak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June inWashington, DC. The conference is being organized by Syllabusx, a group of "international specialists inpublic health and emergency planning events and disaster recovery conferences ."Given the nature of the conference topics, do you concur with recommending Dr. Collins decline theinvitation and refer to CDC?Thanks for your input.KaraFrom:Sent:To:Cc:Subject:Alison:Fauci, Anthony (NIH/NIAIO) [E)Thu, 13 Feb 2020 23:22:27 +0000Alison GalvaniConrad, Patricia (NIH/NIAID) [E]RE: Lancet special issue proposalThanks for the note . I really appreciate your kind invitation, but unfortunately, Iwill have to decline. My plate is already overflowing and I just cannot take onany additional editorial responsibilities . In addition, I am swamped withcoronavirus "stuff" that is not going to end soon. I hope that you understand .Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail Cb) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Alison Galvani (b) (6)Sent: Wednesday, February 12, 2020 2:28 PM ------ ..-.-,= To: Fauci, Anthony (NIH/NIAID) [E] CbH >Subject: Lancet special issue proposalHi Tony,I hope you are well.(b) (4)Thank you so much for your consideration.NIH-001912Warmest regards,AlisonAlison Galvani, PhDDirector, Yale Center for Infectious Disease Modeling and Analysis (CIDMA)Burnett and Stender Families Professor of EpidemiologyYale School of Public HealthYale School of MedicineNew Haven, CT 06520(b)(6)htt p://c idma .yale .edu/NIH-0019 13From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Thu, 13 Feb 2020 23:10:07 +0000Conrad, Patricia (NIH/NIAID) [ElFW: Personal connectionPlease set this up (5 minutes) for Monday.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Conrad, Patricia (NIH/NIAID) [El- -------- (b)(6)] Sent: Wednesday, February 12, 2020 8:58 AM -------=-,-:-= To: Fauci, Anthony (NIH/NIAID) [El- ------- (b)(6) Subject : FW: Personal connectionThis guy called last night and seemed to know you - let me know if and where youwant me to direct him.Or maybe do a call with you on a quieter day - Monday on Pres day holiday?Patricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaime r:NIH-001914The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be usedby anyone who is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not acceptliability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives .From: Banner, Jon {PEP} (b)(6)>Sent: Tuesday, February 11, 2020 9:44 PMTo: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] ----------- (b)(6)Subject: Personal connectionDear Dr. Fauci,Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer ofWorld News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also ExecutiveProducer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Backthen, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and deathissues of our time, and your input was of enormous value to our viewers and the general public.Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . Iwas hoping you could help us identify an expert to provide similar insight and analysis for our companyas we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel,I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want to take up toomuch of your time.If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeplyappreciate it if you could connect me with another expert over email.Thanks very much, and hope you are doing well!Warm regards,JonNIH-001915From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Thu, 13 Feb 2020 22:47:23 +0000Eisinger, Robert (NIH/NIAID) [E]Subject:Attachment s:FW: Institutional request for informationCll 2020 CDC import permit .pdfAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sen sitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Fried, Linda P. (b)(6)Sent : Thursday, February 13, 2020 12:45 PMTo: Redfield, Robert R. (CDC/OD) (b)(6) Fauci, Anthony (NIH/NIAID) [E](b)(6)Cc: Conrad, Patricia (NIH/NIA ID) [E] ----======(~b)(6~) >~; G oldman, Lee (b)(6); Booth, Jane ________ CbH_ ; Katznelson, Ira I.======== (~b)~(6;;)--Subject: Institutional request for informationDear Ors. Redfield and Fauci,I am writing on behalf of Columbia University, which has received a request from Dr. Ian Lipkin totransfer live novel coronav irus from Hong Kong to his BSL3 facility at the Univers ity. As we evaluate hisrequest , we note that he has approval from a CDC official to import the virus (see attached) . However,as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you:1. Is the CDC or NIH overseeing the distribution of the live virus in the U.S.?2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtainit directly from other sources?3. If it can be obtained from other sources, what sources will be permitted? For example, theChina or Hong Kong CDC or University of Hong Kong?4. If you are to be the sole source, when wou ld you expect to have a process for consideringrequests?NIH-0019 16NIH-0019175. If someone wishes to travel to China to work on the live virus, are there any travel restrictionsother than the self isolation/quarantine already in place (and of course subject to change overtime)?Thank you very much for your help with these important questions as we all try to do our best tocontribute solutions to this health crisis.With best regards,LindaLinda P. Fried, M.D., M.P.H.Dean and Delamar Professor of Public HealthProfessor of EpidemiologyMailman School of Public HealthProfessor of Medicine, Vagelos College of Physicians and SurgeonsSenior Vice President, Columbia University Irving Medical CenterColumbia UniversityFrom: Fauci, Anthony (NIH/NIAIO) [E)Sent : Thu, 13 Feb 2020 22:44:12 +0000To: Stoffels, Paul [JJCUS]Cc: Riccobene, Kim [JJCUS];Van Hoof, Johan [JRDBE);Conrad, Patricia (NIH/NIAID)[E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID)[E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E]Subject : RE: COVID-19 vaccine developmentPaul:Thanks for the note. I will have Patty Conrad {copied here) try to worksomething out for Feb.21 st. My schedule is at the mercy of the White House andthe Congress and so I cannot guarantee anything right now.Best Regards,TonyAnthony S. Fauci , MDDirecto rNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail (b)(6)The information in this e-ma il and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expre ssly made onbehalf of the NIAID by one of its representatives .From: Stoffels, Paul [JJCUS-] ------ (b)(6)>Sent : Thursday, February 13, 2020 9:42 AMTo: Fauci, Anthony (NIH/NIAID) [E) ----- --(:b=aH=6)>Cc : Riccobene, Kim [JJCUS-) ------- (b)(6); Van Hoof, Johan [JRDBE)- ------- (b)(6)>Subject : COVID-19 vaccine developmentDear Tony,Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine.(b) (4)NIH-001918If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, Iwould much very appreciate .(b) (4)Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I willbe in Europe till the 19th .Best regards,PaulPaul Stoffels, MDVice Chairman & CSOJohnson & Johnson(b)(6) (Mobi le Europe)(Office US)NIH-001919From:Sent:To:Subject:Fauci, Anthony (NIH/NIAID) [E)Thu, 13 Feb 2020 03:16:08 +0000Barasch, Kimberly (NIH/NIAID) [C)FW: Run of show- 2/13, 9-l0am White House Roundtable on COVID-19Make sure that this is in my folder.From:S elgrade, Sara (NIH/NIA ID) [El- ------- (b)(6}> Sent: Wed nesday, February 12, 2020 3:16 PM -----~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)Cc: NIAID OCGR Leg <NIAIDOCGRLeg@mail.nih.gov>; Conrad, Patr icia (NIH/NIAID) [El(b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet,Courtney (NIH/N IAID) [E] (b)(6)Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19Dr. Fauci,Please see below for information we have received from HHS thus far regardingtomorrow's briefing on coronavirus at the White House. Patty has submitted yourinf onnation via the WA YES link for the event. We are checking with HHS ASLto make sure your clearance has been proce ssed.We will share any additional information as we receive it. Please let me know ifyou have any questions.Thanks,SaraWhite Hou se Congressional Roundtable on CoronavirusDate: Thursday, February 13Time: 9:00 - I 0:00 a.m.Location: Roosevelt RoomRun of show:• Acting Chief of Staff Mulvaney will open the proceedings and briefly frameall that we are doing and why we have asked the Members to assemble (togain their insight and to seek their wisdom).NIH-001923NIH-001924• Anne Schuchat will give a brief overview of current status and materialissues.• Anthony Fauci will give a brief explanation of our understanding of thevirus and development of countermeasures.• Brig Gen. Paul Friedrichs of DoD will provide a brief status report on forceprotection.• Acting Chief of Staff Mulvaney will open the floor for questions andmoderate the proceedings - possible that White House legislative affairs willstand in here (Eric Ueland or Mike McKenna).Expected participant s:Members (confirmed RSVPs thus far)Senator James RischLeader McCarthyRep. Kay GrangerRep. Greg WaldenRep. Nita LoweyBriefersDHS-Alex ZemekCDC- Dr. Anne SchuchatNIAID-Dr. Tony FauciASPR- Dr . Bob KadlecFDA-Dr. Steve HahnDHS - Ken CuccinelliNSC - Anthony RiggieroNSC - Matt PottingerState - Stephen Biegun (tentative)DOD - Brig Gen. Paul FriedrichsFrom:Sent :To:(b)(6)Wed, 12 Feb 2020 11:02:30 -0500John LauermanSubject : Re: InterviewI tried calling but the call would not go throughOn Feb 12, 2020 , at 6: 15 AM, John Lauerman (BLOOMB ERG/ NEWSROOM:)<jlauemmn @bloomb erg .net>wro te:Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of majordrugmakers stepping up to make coron av irus vaccine , a nd mycolleague James Paton is working on a story about that issue .J ames ' s story has to do with a bi osecurity initia t ive related tothese types of t hreats at GSK tha t was started in 2016 and quicklypu t on t he bac k bu r ner . I do n 't know whe t h e r you 'd want t o commen ton the company or its activities i tse lf , bu t wou ld b e he l pfu l ifyou could talk about t he im p ortance of ge ttin g big drugmakersinvolve d in helping t o fill t he need f or new vaccin es . I 'm inGeneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe wecan t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp ,where my number i s (b)(6). Ple ase let me know if/whenyou ' re free . Thanks and regards , JLFrom : John La uerman (BLOOMBERG/ NEWSROOM: ) At : 02/07/20 15 :53 :34To : (b)(6)Sub j ect : RE : Int erv i ewUnder stood . Hope you ge t a chanc e to r es tFrom : a f auci@niaid . nih .g ov At : 02/07/20 15 : 51 : 39To : J ohn Laue r man (BLOOMBERG/ NEWSROOM: )Sub jec t : RE: InterviewSorry John. I am totally tied up right now and besides, Iam completely hoarse and can barely speak. Let us trysome other time.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)NIH-001925FAX : (301) 496-4409E-mail: Cb) (6)The information in this e-mail and any of its attachments is confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intended recipient . If you have received this emailin error please inform the sender and delete it from your mailbox orany other storage devices . The National Institute of Allergy andInfe ctious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender 's own and not expressly made on behalf of theNIAID by one of its representatives.From: John Lauerman (BLOOMBERG/ NEWSROOM :)<jlauerman@bloomberg .net>Sent : Monday, February 3, 2020 8:1-8- A-M-- -~~ To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6)Subje ct: InterviewHi Dr . Fauci : How are you? I 'm wri t ing t o seewhether we can talk again fo r a few minutes.We' r e worki ng on a b i gg i sh p iece abou t t hel arger b i o-secur i t y i ssue wor l dwi de a nd wh a t t hecoronavi r u s outbreak tells u s abo ut it . What canwe do abou t t he weakes t lin ks in d i sease co nt ro lin p oore r n a t ion s in Af r ic a , Asia a nd e l sew here?The WHO today bro ug ht up the impo r tance ofaccess to health care along with spending onp ub li c h ea l t h, a nd c l ear l y t hi s i s a n issue inpoo r co un ties . Is it also important ininfectio us disease in the US and if so, is itad e qua t ely recognized? Compa nie s a nd researchcenters have made h ug e strides in qu ickdevelopment of vaccines and dr ug s ; what can takei t t o t he nex t level? Is t he r e a ny t hing t ha tco ul d be done to attract more companies to thisfield? What kind of n ew t e chnologi e s can help ust rack ne w v i ruses in t he communi t y? I ' ve bee nt a l kin g wi t h peop le using ha ndhel d n ano por eseq uence r s to track coronavi r u s and Ebola ; whatel se i s ou t t here? Do we nee d t o do a b e tt er jobof t racking t he move men t of peop le a nd goods?Also glad to get any other observations . Pleasec a l l t oday or t omorrow mornin g at ~o r le t me know when a nd a t wh a t (number to call you . Thanks and re g ards , lookforward t o he ar in g from you , JLNIH-001926John Lauerman, Bloomberg News3 Queen Victoria Street, Lond-o-n-, -U-K- --=--=-:= tel. +44 (0) 2035 251028 cell --------- Cb)(6) http ://www .bloombe rg.comhttp://www .bloomberg.com/prog nos isNIH-001927From: (b)(6)Sent : Wed, 12 Feb 2020 10:24:06 -0500To: Daniel LuceySubject: Re: Update IDSA Science Speaks post today# 10: PPE mass production andPOlyclonal/mAbs Rx PReP and PEPThanks danOn Feb 12, 2020, at 9:34 AM, Daniel Lucey Cb) (6)>wrote: ---------Bob K., Tony and Bob (Redfield),Given the news of health care personnel in Wuhan and Hubei being infected, andacute shortage of PPE for COVID-19, I posted these Q&A s on the ID SocietyAmerica "Science Speaks" website as the 10th in a series of my updates sinceJanuary 6th.The final Question asks and answers that mass production of COVID-19 PPEshould occur now.DanHong Kong Feb. 12, 2020bttps ://sciencespeaksblog. org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for- treatmen t-and -prophylax is/NIH-001928From:Sent:To:Cc:Fauci, Anthony (NIH/NIAID) [E)Wed, 12 Feb 2020 15:23:15 +0000Folkers, Greg (NIH/NIAID) [E)Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C]!';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meetingat the Ritz Carlton (22nd and M St. NW), Washington, D.C.Attach ment s: image003.jpg, image004.jpg, imageOOS.jpgOkay. Go with itOn Feb 12, 2020, at 9:38 AM, Folkers, Greg (NIH/NIAID) [E](b)(6) wrote:Will addI would vote fo r: no slides-I would send these three papers (all on director's page) - CoV, Ebola, Ending HIV<image003 .jpg>Foreign Policy<image004 .jpg><image005 .jpg>From: Conrad, Patricia (NIH/NIAJD) [E)- -------- (b)(6) Sent : Wednesday, February 12, 2020 9:11 AMTo: Folkers, Greg (NIH/NIA ID) [El ~======'~~ Cc: Fauci, Anthony (NIH/NIAID) [El _______ C_b<>.; Barasch, Kimber ly (NIH/NIAID)[CJ (b)(6)Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting atthe Ritz Carlton (22nd and M St. NW), Washington, D.C.Kim - pis add all to the folder thxNIH-001929G - this needs to be added to matrix. IT was a "fires ide chat" that wethought would not include slides but see below -they are ok with afew slidesWill need to discuss things to send and topics given the "theme"Patricia L. Con radPublic Health Analyst andSpecial Assistant to the DirectorNation al Inst itute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Mary land 20892(b)(6)301-496-4409 faxDisclaime r:The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. Itshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergyand Infectious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and notexpress ly made on behalf of the NIAID by one of its representatives.From: Marlene Colucci <mcolucci@businesscouncil.com>Sent: Tuesday, February 11, 2020 6:29 PMTo: Conrad, Patricia (NIH/NIAID) [El --------=- (bs)-( =6)Cc: Adrienne Ball <aball@businesscouncil.com>; Gillian Auger<gauger@businesscouncil.com>Subject: Re: Business Council - Invitation to speak at the February 20-21, 2020 meeting atthe Ritz Carlton (22nd and M St. NW), Washington , D.C.Patty,I wanted to check back with you and Dr. Fauci on a few things in advance of his firesidechat with David Rubenstein on Friday, February 21.• Are there any art icles that Dr. Fauci thinks would be useful to send out to our CEOsin advance of the discussion (it may be something related to the Coronavirus orsomething that looks at the future of health and what CEOs should be thinkingabout in the next decade?NIH-001930• The theme for our upcoming meeting is "The Next Decade - Major trends intechnology, geopolitics, politics, economy and health" . I have attached a copy ofour Draft CONFIDENTIAL and list of attendees for Dr. Fauci's reference .• During his discussion with David Rubenstein, are there any slides he would like touse for reference? We do not use a lot of these but thought there might be slidesthat wou ld aid in his discussion? Just let us know.Warmest regards,MarleneMarlene ColucciEXECUTIVEDIRECTOR'I BUSI TESS~ l0L 1\.C.L ..T: 202-298-7650C: (b)(6)F: 202-785-0296On Feb 5, 2020, at 9:19 AM, Marlene Colucci<mcolucci@businesscouncil.com> wrote:Thank you Patty for checking. As soon as I can find out whether Dr. Collinswi ll also be a part of the discussion I will work on setting up t hat call. Ivebeen pressing their office so fingers crossed!MarleneMarlene ColucciEXECUTIVEDIRECTOR"I BUSINESS~ COL.:\JCILT : 202-298-7650C: (b)( 6)F: 202-785-0296NIH-001931On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E]---------- (b)( wrote:Good morni ng:Dr. Fauci will not be able to att end the dinner thenight befor e but wanted me to thank you fort hink ing of him.Best,-patt yFrom : Marlene Colucci <mcolucci@businesscouncil.com >Sent: Friday, January 31, 2020 2:00 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------ .(-b..H..,=6JCc: Conrad, Patricia (NIH/NIAID) [E] CbH6; JDavid Rubenstein (b)( ; MaryPatDecker ------------ (b)(6) Subject : Business Council - Invitat ion to speak at the February20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW),Washington , D.C.Dear Dr. Fauci,On behalf of our co-chairs for the winte r meeting of TheBusiness Council, David Rubenstein of The Carlyle Group andGinni Rometty of IBM, we wou ld like to formally invite you toparticipate in our meeting on February 20-21, 2020 inWashington, D.C. The theme of the meeting is "The NextDecade." (See formal invitation attached as well as list of CEOmembers).We would like for you to participate in a 50 minute fireside chatwith David Rubenstein (and possibly Dr. Francis Collins) todiscuss the current coronavirus as well as what we shouldexpect in the next decade. We want to give our CEOs insightsinto what the next 10 years will bring in terms of detection,diagnosis and treatment of diseases. All conversations arestrictly off the record and closed press. We wil l cover all lodgingand transportation.As you know, The Business Council is comprised of the chiefexecutive officers of the largest global corporations,representing all segments of the economy . We expect at least150 CEO members, spouses and speakers to be in attendance.NIH-001932As a participant you and your spouse are also invited to join usfor our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is thebest opportunity for you to meet our CEO members andspouses, speakers and other special guests in an informalatmosphere.If you are interested and available, please let me know. We canalso set up a very brief call with you to discuss any additiona ldetails and answer any questions you may have. We lookforward to hearing from you and would be honored to have youparticipate wit h us again.Warmest regards,MarleneMarlene ColucciEXECUT IVEDIRECTOR~ BUSINESS ·11• ~ COL '!CTLT : 202 -298-7650C: (b)(6)F : 202- 785-0296i:@H@Vit3w0\4.2c5.t.a7t.a nso Al!ll1etric 2109Vl~wpointJanuary 23. 2020Coronavirus Infections-More Than Just theCommon Colde,,11.. w, P""""'-1o1•0 .•. ..,.,0 """"°"·"°'..,,,.,f,.1.W,,.l,.fll>l1o oy~ ,....,,.,,...I, ."f"".'-il.~,1-t!o<,.,.,..,/Ml,\. P\.ll»ihNl<.>. nSl ,,,--, l).10/0, cir, IQ 1001/1,oN.JQX)flmNIH-001933AI\OUl'!fNIOn the Front Lines of the TrumpAdministration's Ebola ResponseThe IJnilal S\.11ClS\. '15m ounlOOn wide ~ (t,JlOO.SC\t0h e~ <l.ool)•ou1bfc:l.l,;."o-1n fy ~on.Ending the Human Immunodeficiency VirusPandemic: Optimizing the Prevention andTreatment Toolkit s oClinicoJ f11k<.~ Di~.>e~, Volu1TW69' , b,ue 11, LS De<.e,nbt-r2 0 tt. P•g~ 1n :>-2>l 1,.,UJ>~/irtn, MY ICJ IC"~ilffd/c ,,,,.lHPubUJhed: 24Octobet2019 Arlk le hlstory •NIH-001934NIH-0019351/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09ViewpointJanuary 23, 2020Coronavirus Infections-More Than Just theCommon Coldc..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W>A11thofAf1f1,,f1'0f1I'\ M-.1l"~f ~ •tton"'-'" ~- -13.1010. dol 10100t/!,,m,ll0 l001'>1NIH-001936ARGUNCTNOn the Front Lines of the TrumpAdministration's Ebola ResponseThe t:nitcdS latest i,., mounteda wide r.mgiQgr cspoo.<toe t he btelt dc:>dl)'o utbrc-'o1s1 o<n. ly~can.NIH-001937Ending the Human Immunodeficiency VirusPandemic: Optimizing the Prevention andTreatment Toolkit s oC/inicollnf«IX>U1 D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117,I tlJ)';//dol.org/ l O.lO'J]/cid1<1t' :ISPubtiffled: 24 Oelobet 2019 Artkle history •NIH-001938From:Sent:To:Cc:Subject:Fauci, Anthony (NIH/NIAID) [ElWed, 12 Feb 2020 12:04:55 +0000Cassetti, Cristina (NIH/NIAID) [ElConrad, Patricia (NIH/NIAID) [ElFW: epiqar for Coronavirus assistancePlease handle. Thanks.From: Daniel Goldberg <daniel@eng.us>Sent: Tuesday, February 11, 2020 11:18 PMTo: Fauci, Anthony (NIH/NIAID) [El <afauci@niaid.nih.gov>Subject: epiqar for Coronavirus assistanceDr. Fauci,I wanted to reach out to see if epiqar (https://ep iqar.com/) can help your efforts with theCoronavirus- we are the only system in the world built for remote surgical help & interactiveemergency surgeon support over the web browser.epiqar has created the most advanced surgical video collaboration technology, allowingsurgeons to consult and train remotely on a low-cost and easy-to-use online surgicalcollaboration platform and Cloud-archiving system built for the operating room. With theoutbreak of Coronavirus, this has become more vital as surgeon mobility and access to criticalsurgical spaces in need of more help are severely limited, and specialists will not risk enteringspreading viral hot zones.Patient care isn't just a concern with the virus itself, but with the host of medical issues facingpatients that will no longer be treated by local specialists easily, and facing caregivers: surgeoninvolvement from around the world is needed urgently.Although epiqar is an American company, our rollout in recent months has been inFrance, making selected French institutions the most prepared in the world for remote videocare. We obviously weren't anticipating the Coronavirus and now we're dedicated to deliveringour technology to where the world needs it asap.epiqar 's parent company ENGAUGE (https://eng.us/) is a state-of-the-art online healthcarecompany for surgeon training and has served clients such as Johnson & Johnson , IntuitiveSurgical, and many other of the world largest & smallest medical device companies.ENGAUGE has helped surgeons all over the world have access to secure online training thathas improved their understanding of the innovations in robotics and many of the latest surgicaltechniques and medical devices for best patient care.I've linked a whitepaper below with details of the system's use. Please let me know if you wouldlike to speak further and/or need anything additional.Thanks,NIH-001939Dannywww .epigar. comepiqa r I whitepaperDaniel GoldbergCEOENGAUGEwww .eng.uswww .epiqar.comThe world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platformus 888.615.7874EUROPE 44 2031399059From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Wed, 12 Feb 2020 00:16:12 +0000Conrad, Patricia (NIH/NIAID) [ElSubject : FW: AMA news interview request: What to tell your patients about COVID-19Let us di scuss.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Sara Berg <Sara.Berg@ama -assn.org>Sent: Tuesday, February 11, 2020 4:55 PM -------=-=-c= To: Fauci, Anthony (NIH/NIAID) [El (b)((;)>Subject: AMA news inte rview request: What to tell your patients about COVID-19Dear Dr. Fauci,My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because youhave shared a lot of great information about COVID-19 with the JAMA networ k. I know you are verybusy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rviewabout what to tell patients who suspect they have COVID-19? This would be an AMA news art icle forphysicians about what to tell patients. The CDC has a list of preventive steps :https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html .This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be"Call before you come in." Do you think this is something you would be available to participate in?I look forward to hearing from you.Thank you ,NIH-001940NIH-001941AMA~Sara BergSenior Communications SpecialistSara.Berg@ama-assn.orgOffice: (312) 464-410400000AMA membership: Join or renew today!MEMBERSHIPMOVESMEDICINE ...From:Sent:To:Subject:Attachments :Fauci, Anthony (NIH/NIAIO) [E)Wed, 12 Feb 2020 00:13:52 +0000Cassetti, Cristi na (NIH/NIAID) [E]FW: 2019 nCoV brief fyi (2+ pages)Brief 2019 nCoV host Se status.docPlease handle. Thanks.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBui lding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Michalann Harthill (b)(6)Sent: Tuesday, February 11, 2020 3:41 PM -------=-:--:= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) :.::========-=.,~ Cc: Morens, David (NIH/NIAID) [E] ---------- (b)(6) Subject : 2019 nCoV brief fyi {2+ pages)Dear Dr. Fauci,Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, HubeiProvince, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4pages, ~ 70 refs, no graphics)Best regards,Michal HarthillGHI, Inc., Frederick, MD(b)(6)NIH-001942From:Sent :To:Subject:Attachment s:Fauci, Anthony (NIH/NIAIO) [E)Wed, 12 Feb 2020 00:05:00 +0000(b)(6)FW: take a look at figure 3 of the new nejm papernejmoa2001316.pdfSee Greg/ David comment below .Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail. (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sen sitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Folkers, Greg (NIH/NIA ID) [E) --------- (b) (6)> Sent : Tuesday, February 11, 2020 2:50 PMTo: NIAID OD AM <NIAIDODAM@niaid.nih .gov>Subject: take a look at figure 3 of the new nejm paperThanks davidNIH-001943(b) (5)From: Folkers, Greg {NIH/N IAID) [E)Sent : Tuesday, February 11, 2020 10:04 AMTo: NIAID OD AM <NIAIDODAM @niaid.nih .gov>Subject: this is t he nejm paper discussed this a.m.That asf is opining on(b) (5lDisclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sionsof U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sentmy views nor those of NIAJD, NIH, HHS, or the U.S. gove rnment.NIH-001944From:Sent :To:Fauci, Anthony (NIH/NIAID) [ElTue, 11 Feb 2020 23:58:00 +0000NIAIDODAMSubject: FW: Keynote Invitation: 3/20 CSIS Coronavirus Public EventThis could be good since it is local. Let us discuss.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Stephen Morrison <SMorriso@csis.org>Sent : Tuesday, February 11, 2020 1:20 PM To: Fauci, Anthony (NIH/NIAID) [El --------------=---,,-(-b)(:6)- = Cc: Anna Carroll <ACarroll@csis.org>; Samantha Stroman <SStroman@csis.org>; Conrad, Patricia(NIH/NIAID) [El (b)(6)Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public EventDear Dr. Fauci,I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at aCSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island AvenueNW) . The event will focus on the science, economics, and politics of the coronavirus and will featureexperts on Chinese and international politics and economics, as well as public health . We would ask youto speak approximately 1:30-Z:OO pm. Your keynote would be followed by a panel discussion and aclosing address, and we invite you to stay for as much of the event as you are able . Please find the fulldraft agenda and speakers for the event below for your reference .We would be honored to have you participate in this important and timely event. Thank you for yourconside rat ion, and please let us know if you would like to discuss further or if we can answer anyquestions. We look forward to hearing from you .Best,SteveNIH-001945NIH-001946Draft Agenda:1:30-2 :00 pm - Opening KeynoteDr. Anthony Fauci, NIAIDIntroduced by Steve Morrison, CSIS Global Health Policy Center2:00-2:50 pm - Panel Discussion{The economics/business] Joyce Chang, JP Morgan (confirmed){The politics] Jude Blanchette, CSIS Freeman Chair in China Studies (confirmed)[The foreign politics] Melanie Hart, Center for American Progress (to be invited), or BonnieGlaser, CSIS China Power Project{The public health] Steve Morrison, CSIS Global Health Policy Center (confirmed)Moderato r : Scott Kennedy, CSIS Trustee Chair in Chinese Business and Economics2:50-3 :30 pm - Newsmaker SpeechMatt Pottinger, NSC (to be invited)Moderato r and Follow-up Interview: Bonnie Glaser, CSIS China Power ProjectJ. Stephen MorrisonSenior Vice President & Director, Global Health Policy CenterCenter for Strategic and International Studies (CSIS)1616 Rhode Island Ave NWWashington D.C. 20036(202) 775-3276From:Sent :To:Fauci, Anthony (NIH/ NIAIO) [ElTue, 11 Feb 2020 23:45: 51 +0000Lerner, Andrea (NIH/NI AID) [ElSubject: FW: Pharmacist's/ Prescriber 's Letter Review Request - Coron av irusPlease t ake a look at this and respond for me.Tha nks,TonyAnthony S. Fauci , MDDirecto rNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)( 6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave rece ived this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Jennife r Nieman <jnieman@pl et ter .com>Sent : Tuesday, Februa ry 11, 2020 11:00 AM ------- =---c-c= To: Fauci, Anth ony (NIH/ NIAID) [E] --------- (b)( 6) Subject: Pharmacist's/ Prescriber's Lette r Review Request - CoronavirusDear Dr. Fauci,In the March 2020 issues of Pharmacist 's Letter and Pre scriber's Letter, we plan to write aboutcoronavirus.Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians.We are not affiliated with any other group , organization, or company. We are 100% subscribersupported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drugtherapy . Each month we turn to experts like you to help us pin down the most relevant and importantinformation to share with our readers. Our newsletter is well known for being concise and accurate. Youwill notice the excerpt we are sending you is relatively short .NIH-001947NIH-001948We would be most appreciative if you would take just a few moments to review what we have written foraccuracy and content. Please share any comments or suggestions for changes you may have on thearticle.In order to incorporate your comments into the final Letter, please let me hear from you by Monday, Feb.17th. I can be reached by email jnieman@PLetter.com or phone (402) 660-4715.I look forward to your reply.INFECTION CONTROLThe ongoing ou tb reak of t he novel coronavirus wi ll raisequest i ons about how t o li mi t t he spread of r e sp i ratoryinfec t ion s .Managing this situation is similar to outbreaks of SARS andMERS ... s in ce coro nav i ruses are spread by resp i ratory secret i ons .Pu t t he risk in perspect i ve t o calm worr ie dpatients . .. since it doesn ' t come close to the risk of influenza .For example, over 35 MILLION U. S . patients got the flu lastseaso n . . . wi t h about 500 ,000 ho sp i ta li za t i ons a nd 34 ,000 deaths .Emphasize getting a flu vaccine each year .And us e this coronavirus outbrea k as an opportunity tostress infection control ... since there ' s no treatment o r vaccineyet .Reinforce p roper han d h yg iene . Educate t ha t ha ndwas hingwi t h soap a nd water i s t he best way t o g e t r i d of germs . Advisewas hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABCso ng .Or recommend using a han d sani t izer wi t h a t leas t 60%alcohol if handwashing isn ' t practical . Many prod u cts containthis much .But tell patients to be wary of efficacy claims . Fore xamp l e, ha nd sa ni t i zers are s ho wn t o kill en v e l oped v i ruses .Coronavir u ses are enveloped viruses ... b ut they aren ' tspecifically st u died .NIH-001949Tell patients to avoid touching their eyes, nose , andmouth .Clear up confusion about mas ks. Emphasize that mas ks arefor SICK patients ... to help keep their germs from gettin g intot he a ir .But d i scourage surgica l masks for mos t patients withOU Tsymp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t ol imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th ee yes .I f pat ien ts ask about N95 res p ira t ors , t e ll t hem t hesereq u ire fittin g and training before us e . Save them forhealthcare workers .Caution that unnecessary mask use may contribute toshortages .Continue to ask patients WITH respiratory symptoms to put as ur g ic a l mask on when t he y co me to c l inic .And suggest that sick patients wear a mask at home if inclose contact with infants , elderly , or immunocompromisedpatients .Te ll pat ien t s t o discard masks when da mp ... and t o use afresh one at least daily .Encourage pat ien ts t o s tay home when t hey ' re sick.1. https://www.who.int/emergencies/diseases/novel-coronavirus-20192. https://www.cdc.gov/coronavirus/2019-ncov/index.html3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm4. https://www.who. int/publications-detail/advice-on- the-use-of-masks-the-community-durinq-home-care-and-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(2019-ncov)-outbreakSincerely,Jennifer A. Nieman, PharmD, BCPSAssocia te Editor, TRC HealthcareM: 402-660 -4715 E: jnieman@pletter.com W: TRCHealthcare .comPham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians UniversityFrom:Sent:To:Cc:Subject :Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 23:06:37 +0000Billet, Courtney (NIH/NIAID) [E]Conrad, Patricia (NIH/NIAID) [E]FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily]Can we please get someone to fashion answers for me to edit and send to her.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail Cb()6 )The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: ~fm/§ <ymhan@stimes.cn>Sent: Monday, February 10, 2020 2:54 AM ------ ..-.-,= To: Fauci, Anthony (NIH/NIAID) [E] (bH >Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily]Dear Prof. Anthony,I am yangmei Han, a journal ist from CHINAS CIENCED AILY.Chi na Sc i ence Da i I ya newspaper in Chinese, pub I i shed by The Chinese Academy of Sciences.ISRecently, your article " Coronaviru s Infectio ns- More Than Just the Common Cold "mention about vaccinesinterested and there areget more informations.research 1n NIAID. We aresome questions and I want to1, What is the current research progress about vaccines 1n NIAID?NIH-0019502-.. What are the factors restricting the development of vaccines? and did you breakthrough them?3 .. What is the standard of vaccine that can be injected to patients? and accordingyour forecasting, how will it work?4 .. Can this vaccines research play a role in the 2019-nCoV? Or as a treatment for acommon infectious disease in the future?5, Does vaccines have side effects? how can we restrain it?6, If vaccines research success in a certain country, Will it be open to theworld? if it will , what conditions will need for open?if you could, we would I ike you rep ly as soon as possibleThank you very muchI am looking forwa r d to your reply!Si nee re I y yours ,Yangmei Han (Miss)~tw~q:oi of:.I:.1~t& t * tnc :,:1)p t c~BlB~:B y mhan@stimes .cn;576942717@qq .eomit i! : (b)(6)i'!EiJt:~ t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~NI~H:±J:q:iOOf~:.t1t:.~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M ~ ~ * ~~~~· §&~~~m-~~~~~$·~-~~~~-%~M~••·NIH-001951From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 20:54:02 +0000Natalie RahhalRE: Interview re: coronavirus patient characteristicsIf th is is true, which it might not be, there is no clear explanation for why rightnow . There will likely be studies coming out that say that the relative proportionof male:female is closer to 50:50. Even one of the ones that you quoted was54%Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone Cb()6 )FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Natalie Rahhal <Natalie .Rahhal@mai lonline .com>Sent: Tuesday, February 11, 2020 1:55 PM ------- ~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: Interview re: coronavirus patient characteristicsHi Dr Fauci,I'm sure you're extraordinarily busy right now, but I've seen several stud ies and reports that coronavirusseems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study youreference). I was wondering if you might have any comments to offer on why this mig ht be?Thank you,Natalie A RahhalActing US Hea.lth EditorDailylll4'lil.comNIH-001952Daily Mail Online I 51 Astor Place, 9th floor, New York NY 10003Tel: +1212402 9086Mobile : (b) (6)Twitter : https ://twi t ter .com/nata lier78?1ang=enEmail: Natalie.rahhal@mailonline.comDisclaimerThis e-mail and any attached files are intended for the named addressee only. It contains information, which maybe confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( orauthorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received itin error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd.Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England.NIH-001953From:Sent:To:Subject :Gary:Thanks for the note.Best,TonyAnthony S. Fauci. MDDirectorFauci, Anthony (NIH/N IAID) [E)Tue, 11 Feb 2020 20:10:45 +0000Nabel, Gary / USRE: WHO meeti ngNational Institute of Allergy and Infectious DiseasesBuilding 3 I, Room 7 A-033 I Center Drive, MSC 2520National Jnstitutes of HealthBethesda, MD 20892 -2520Phone: (b) (6)FAX: (301) 496-4409E-mail: (b)(6)(b) (4)The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . Itshould not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in errorplease inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute ofAllergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's ownand not express ly made on behalf of the NIA ID by one of its representatives.-----Original Message--------------=-=-= from : Nabel, Gary /US (b) ((b)(Sent: Tuesday, February l l , 2020 1:19 PMTo: Fauci, Anthony (N1H/N1AJD)[ E)- -------- Subject: RE: WHO meetingNot a problem. I j ust wanted you to know that I was willing to help.BestGary-----Original Message-----From: Fauci, Anthony (NlH/NlAID) [E] --------- (b)( Sent: Monday, February 10, 2020 3:07 PMTo: Nabel , Gary /US (b)( 6)>NIH-001954(b) (4)Subject: [EXTERNAL] RE: WHO meetingEXTERNAL: Real sender is (b)(6) _______ _,T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: (301) 496-2263FAX: (301) 496-4409E-mail: afauci@niaid.nih.govThe infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. ltshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox. or any other storage devices. The National Instinite ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's ownand not express ly made on behalf of the NIA.lD by one of its representatives.-----O riginal Message- ---- ---------=--=-= From: Nabel, Gary /US (b) (Sent: Monday, February I 0, 2020 2: 17- -P-M- ---~~ To: Fauci. Anthony (NTH/NIAlD)[ E]_ _____ C)bC_,Subject: WHO meetingHi TonyThanks for taking the time to talk and help with the HTV trispecific work last week. I appreciate your efforts.While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend buthave not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunateand to their detriment. In any case, please let me know ifl can help in any way.Best regardsGarySent from my iPhoneNIH-001955From:Sent:To:(b)(6)Tue, 11 Feb 2020 11:22:43 -0500Mart in BlaserCc:(NIH/NIAID) [E]Subject:Conrad, Patricia (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIAID) [E];Lane, CliffRe: SARS 2003, Influenza 2009 and the presentMarty:Than.ks for the note. Indeed, immune sera is foremost on our mind as are mAbs. Hope that allis well with you.Best,TonyOn Feb 11, 2020 , at 9:55 AM, Martin Blase rCb)( wrote: ------------Dear Tony,I dont mean to bother you, but I have a suggestion, in case you have notconsidered it.China will have hundreds of thousands of Coronavirus surv ivors . Their convalescent(immune) serum is valuable. China should try to collect it and give it as a good-willgesture to people around the world.For moderately to seriously ill people, Immune serum should save many lives.If cases start to come here, we also should collect serum from survivors, buthopefully we will be very late in the pandemic, and it is not needed because of allof the others th ings you are doing.Thank you for everything you and NIAID are doing!Best wishes, Marty(Just as in SARS, the Ro for nCo-2019 is higher in hospitals than in the community,but it still is too high in the community).Martin J. Blaser, M.D.Henry Rutgers Chair of the Human MicrobiomeProfessor of Medicine and Microbiology-RWJMSDirector, Center for Advanced Biotechnology and MedicineRutgers University679 Hoes Lane West, Room 106APiscataway, NJ 08854Office Phone: (b)(6) Fax: 7 2-235--fi3._- 1_8 - __-___-_ - ~=Emili oo~NIH-001956httPs ://cab m.rutgers.eduFrom: Fauci, Anthony (NIH/NIAID) [El (b)(6) ________ ......Sent: Sunday, January 26, 2020 7:16 PMTo: Martin Blaser (b)(6):Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6)Subject: RE: SARS 2003, Influenza 2009 and the presentMarty:Many thanks. Th is is very helpful.Best regards,TonyFrom: Martin Blaser (b) (6)Sent: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6)Subject: SARS 2003, Influenza 2009 and the presentWebb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm issionin the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1:1-13. [PMID: 203699561 [Paper of the year, 2004]Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre-symptomatic influenzatransmission, surveillance, and school closings: implicat ions for novelinfluenza A (HlNl). Mathematical Modelling of Natural Phenomena2010 ; 5:191-205.Dear Tony,Thanks for your JAMA piece on 2019-nCoV. Perhaps I can help in asmall way:In 2003, with SARS, the Ro was initially considered to be over 2, but infact that was the conflation of the nosocomial and community rates. In the2004 paper , we showed that nosocomial rate was much higher, and that theRo in the commun ity was between 1 and 2. A lower Ro in the communityaccounts for why modera te public health actions could move it towardextinction--and why it propagated in Beijing, but not Shanghai , in TorontoNIH-001957NIH-001958but not in Vancouver--the Ro in North America became less thanone pretty quickly.To me, one important aspect is the control of respiratory tran smission inthe hospital, avoiding extensive nebulization /aerosolization, or doing so innegative pressure rooms , as for TB isolation.(Treating patient s with robots is a good idea!)In the communit y, standard public health quarantine, contact tracing shouldbe sufficient for staiie rs.Although hundreds of cases are reported in China, the actual number ofinfections is likely much higher. The 41 deaths are the tip of the iceberg ofnot 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%).Although that rate is much better, if the mutating virus becomes verycontagious- then the impact could be similar to 1918 flu. That's whycontainment is so important-and although draconia n, the Chinesegovernment is doing the right thing (as far as we know).When a new pathogen arrives, children often have mild disease but theyare important vectors for transmi ssion in the cotrununity , reaching manyhouseholds. The second paper is the imp01iance of closing schools to minimi zetransmi ssion- This was for flu with a short (pre-symptomatic) incubation , but maybe even more relevant for 2019-nCo V. It is much too eai·ly to even think of this inthe USA, but it may come to this--and sooner will be better than later, when thattime point comes.Happy to help, any way that I can. Thank you for all you and NIAID aredoing!!!Best wishes , MartyMartin J. Blaser, M.D.Henry Rutgers Chair of the Human MicrobiomeProfe ssor of Medicine and Microbi ology- RWJMSDirector, Center for Advanced Biotechnology and MedicineRutgers University679 Hoes Lane West , Room 106APiscatawa y, NJ 08854Office Phon e: (b)(6)Fax: 732-235-53·-1--8- ---~ = Emai l ---------------- (b) (6) http s: I I cabm.rutgers. eduNIH-001959From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 13:22:53 +0000Conrad, Patricia (NIH/NIAID) [E)Subject : FW: Interview/ Coronavirus vaccine - Pazienti.itHave Jen Routh or someone prepare bri ef responses that I can check. Thank s.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Alessandra Lucivero <alessandra.lucivero@pazienti.it>Sent: Tuesday, February 11, 2020 5:35 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( >Cc: Camilla Mantegazza <camilla.mantegazza@pazienti.it>; Irene Bacca <irene.bocca@pazienti.it>Subject : Interview/ Coronavirus vaccine - Pazienti.itGood morning prof. Fauci,my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an Italian health website,followed by over 3 million users every month .We would like to ask you some questions related to the Coronavirus vaccine.We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute.The questions are:• Coronavirus vaccine: when will it be available? What are the difficulties?• Could the Corona virus mutate, if a vaccine cannot be found in time?• Will the vaccine be the solution against Coronavirus?I hope you can be kind enough to answer my questions .I look forward to hearing from you.Thank you very much for you r time.Alessandra LuciveroNIH-001960Alessandra LuciveroResponsabile editorialea lessandra. I ucivero@ pazienti.itPa z Ie nT 1.itII portale della salute dove farsi vedere da uno bravo.Pa:u enTLQuesto messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, lamodifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questodocumento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Viinjormiamo inoltre che questo indirizzo di posta e utilizzato solo a scopo professionale: non si garantisceche la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinatecircostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consigliadi non inviare messaggi di natura personale. Grazie.NIH-001961From:Sent :To:Subject:Attachment s:Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 13:14:45 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: Coronavirus Auto Terminat ionRetrovirus Auto Termination.PDFPlease handle . Thanks.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sen sitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e -mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Pali Nazir (b)(6)>Se nt: Tuesday, February 11, 2020 4:32 AM ---------=-:-= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Chun, Tae-Wook (NIH/NIAID) [E](b)( ; Connors, Mark {NIH/NIA ID) [E] (b)( ; Lane, Cliff'7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__~--=(NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) [El (b)(6J>; Sereti, lrini(NIH/NIAID) [El =====~ (b::);:~(6)Subject: Coronavirus Auto TerminationDear Mrs . / Sir,We have a solution to the new recent global problem Coronavirus (2019-nCoV).Best Regards,Dr. Pali NazirNIH-001962From:Sent:To:Subject :Please handle. Thanks.Anthony S. Fauci, MDDirectorFauci, Anthony (NIH/NIAID) [E)Tue, 11 Feb 202013:12:28 +0000Cassetti, Cristina (NIH/NIAID) [E)FW: coronavirusesNational Institu te of Allergy and Infectious DiseasesBuilding 31, Room 7 A-0331 Center Driv e, MSC 2520National Institu tes of HealthBethe sda , MD 20892 -2520Phone: (b) (6)FAX: (301) 496-4409E-mail: (b)(6)The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. Itshould not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITorplease inform the sender and delete it from your mailbox or any other storage devices. The National Institute ofAllergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's ownand not expressly made on behalf of the NlAID by one of its representatives.-----Original Message-----From : (b)( ·Sent: Tuesday, February 11, 2020 8:0 I AMTo (b)(6)Holbrook , Michael(NIH/NlAID) [CJ .__ ______ C_Hb....>, ; Fauc i, Anthony (NIH/NlA1D)[ E].__ _____ CHb _,,Subject: coronavirusesHello,Working as an occupational physi cian iu F1ance, I would like to draw your attention to the antiviral activity ofproton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not require acidificationof eod osomes for entry into ce lls, as is the case with corona viruses.Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Omeprazole andEsomep razole were also able to inhibit entry of all PV s tested but at high er drug concentrations than may beachiev ed in vivo ... >>.Using omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma), they conc luded that«... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH, only at a concentrationof200μM, higher than that required to inhibit PV entry . Moreover cellular toxicity was observed at thisconcentration after 24 hours ... ».In 2016, Dowall et al. (2) found : « ... Whereas omeprazole and esomeprazole demonstrated in vitro activity againstEBOV, the results were in line with a previou s report using pseudotyped viruses where the values of drugconcentration caus ing 50% inh ibition (IC50) were in the region of 50 μM [10). This suggeste d that doses requi redfor potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosingfor 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasmaconcentrations of 1.59- 9.61 ~tM, 0.51-4.78 μMand 0.15-3.51 μM, respectively .. . >>.However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to beNIH-001963NIH-001964transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group ofthe cysteine of the a subunit of the proton pump.The solution used in 2015 by Jason Long et al. was, as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide).DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanationfor the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 μM (at50 μM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M.This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ationomeprazole can be ionized in the intracellular space but also already in the extrace llular space.Besides, that's probably its advantage: to be ionized and activated where there is an acidic environmen t.Without taking into account the tissue situation and the need that omeprazole must be ionized to be transformed intoan active molecule, it would not be possible to explain the following publications , since it would be impossible toobtain tissue concentrations required:(5)(6)(10)<< Proton pump inhibitors as anti vacuolar-A TPases drugs: a novel anticancer strategy>> (4)<< Anti-Rhinovirus activity of lansoprazole, whkh was probably due to an endosomal anti-acidic mechanism »« The use of omeprazole family compounds was associated with a lower probability of influenza-like illness»« PPls exert an antiviral function by effectively inhibiting virus-specific serine proteases>> (7)« Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8)« The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-A TPase » (9)« Omeprazole blocked another P-type ATPase, A TP7 A (Men kes protein) in human epidermal melanocytes »« pH-dependent anti tumor activity of proton pump inhibitors» ( 11)« V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role foromeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12)« Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acidity in gastritis, areactivated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibitionof V-ATPases in a covalent interaction» ( 13)« proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14)Specifically at the pulmonary level, we observe concerning proton pump inhibitors:« ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), weinvestigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability torestore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJesomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but thisresponse was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo lealka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istentwith a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASLpH in CF airways, which is independent ofCFTR .... » (15)NIH-001965« ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells,exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show thatesomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependentmanner but, chronic exposure, which importantly did not have any deleterious effect on epithelialintegrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTsas a new therapeutic approach for treating CF lung disease ... » ( 15)« ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with thegastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15)« Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16)« Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia »(17)« ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential modelto study proton pump inhibitor-associated pneumonia>> (18)Regarding coronaviruses and Golgi complex:« ... Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediatecompartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) aresynthesized in the ER and move to the ERGIC/Golgi region where they orchestrate assembly of virus by interactingwith the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particlesmust move through the host secretory pathway to be released from infected cells. Coronaviruses are believed tofollow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release ofvirions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemaelate in infection ... >>« . .. Weak bases (which disrupt acidification), v-ATPase inhibitors , and expression of a pH activated proton channelall block a number of membrane trafficking steps( . .. ) One mechanism for how luminal pH can affect vesicu lartrafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensorin endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmicmachinery leading to subsequent vesicle fonnation ... » (19)« ... Phannacological and other manipulations of the pH gradient that result in neutralization of the lumenhave all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgimorphology ... »« ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathwaydisruption phenotypes when overexpressed in mammalian cells ... » (20)« ... The envelope protein (E) of coronaviruses plays an important role in virus assembly ( ... ) Usingcoronavirus infectious clones, it was shown that the transmissible gastroenteritis virus E protein is essential for vimsproduction , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >>« ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediatecompartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably enroute to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22)« ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pumpinhibitors specifically are able to inhibit this increase in Golgi pH . For now, though , it still remains to be seenwhether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of thesecretory pathway ... » (23)« V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi tolysosomes » (24)NIH-001966« ... cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +ATPase, inhibited infection of ceUs with MHV, FIPV, Middle East respiratory syndrome (MERS)-CoV, and VSV,but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibitentry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence,in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassedby low-pH shock. Viral RNA replication was not affected when these compounds were added after virus entry. Theantiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Srcsignaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ... » (25)In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection bycoronaviruses :Tbe equivalent oftbe maximum serum concentration that can be obtained in the human body should be usedand tested in active (ionized) form in vitro .Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbeionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of activetransport.But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of thereactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an activeform, linked to a change in acidity or the depletion of the inactive form.As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellularlevel (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities ofomeprazole with protein E of the corona virus. Protein E is likely to resemb le the protein M2 in its mode of action.In the absence of a treatment recognized as effective in the context of a coronavirus infection and in theabsence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to takeomeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if lhad the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the contextof coronavirus exocytosis , in analogy to the action "off target on the endosomal v ATPase" during endocytosisprocesses.This step, if effective, will not prevent infection , but could lessen its importance, slow the process down and give tbeimmun e system a complementary option to defend itself...Personal experience, using omeprazole in the context of seasonal respiratory viral infections since 2007,reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening isusually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance ofinflammatory state I associate an antihistamine, eg cetirizine.In the context of the coronavirus , I would be temptedshare tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact withpeople at risk of contamination at a distance of less than 2 to 3 metersdivide tbe daily dose of omeprazole into two daily doses in case of minor symptomstake the daily dose of omeprazole in a single dose if the symptoms worsen with repercu ssions on the genera lconditionto resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish.The effectiveness of esomeprazole may be greater than omeprazole.NIH-001967Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reducesecretions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute viral respi ratory diseaseswhich can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) duringprolonged use, thus promoting the risk of bacterial pneumonia (29).The adva ntages and disadvantages may vary depending on the user phenotype of omeprazole with regard tocytochrome P 450 (30).Best regardsJohann es HamburaI. Long J, Wright E, Molesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emergingvira l diseases using existing medicines that block virus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29.doi: 10.12688/fl000research .6085 .22. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus.Viruses. 2016;8(11):277. Published 2016 Oct 27. doi: 10.3390/v81102773. Shin JM, Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. JNeurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.254. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncerstrategy. J Exp Clin Cance r Res.20 10;29( 1 ):44. Published 2010 May 8. doi: 10.1186/1756-9966 -29-445. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kubo H, Nish imura H, Sasak i H. The proton pumpinhibitor lansoprazole inhibits rhinoviru s infection in cultured human tracheal epit helial cells. Eur J Pharmacol.2005;14:201 - 210. doi: 10.1016/j .ejphar.2004 .12.042.6. Gaspari ni R, Lai PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect againstinfluenza- like illness? . BMC Infect Dis. 20 14; 14:297. Publ ished 2014 Jun 2. doi: 10.1186/1471 -2334-14 -2977. Moorn1ann AEBDP, Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors asantiviral agents . United States 1999 Jun. 14, 2005.8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N. Proton pump inhibitors for chronic obstructi ve pulmonary disease.Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 139. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M,Geering K. Nongastric H,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 .10. Matsui MS, Petris MJ, Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole ,a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015Mar; 135(3):834-841.l I . De Milito A, Canese R, Marino ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E, Logozzi M,Mina PD, Santi nam i M, Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proton pumpinhibit ors aga inst human melanoma is mediated by inhibition of tumor acid ity. Int J Cancer. 2009 .12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhance the effects of cytotoxic agents inchemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.531913. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of itsNIH-001968pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I 08:23-35.14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M,Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitorpretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713.15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway SurfaceLiquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11.doi: 10.3389/ fphar.2018.0146216. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC,Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjaepneumonia. Aliment Phannacol Ther. 2012 Nov;36(10):94l-9. doi: 10.1111/apt.12069. Epub 2012 Oct 3.17. Sun DI, Tasca A, Haas M, et al. Na+/H+ Exchangers Are Required for the Development and Function ofVertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/00049297318. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopusmucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol.2015;408(2):292-304. doi: I 0.1016/j.ydbio.2015.03.01319. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261-269. doi: 10.1007/s00418-013-1120-y20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein AltersGolgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019,93 (11) e00015- 19; DOI: 10.l 128/M .00015-1921. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required forefficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID:17037529 DOI: 10.1007/978-0-387-33012-9 3322. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretoryproteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I 05: 1215.23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019).https://doi.org/10.1186/s l2985-019-1182-024. Pamarthy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation ofsignaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I 0.1 I 86/s 12943-018-0811-325. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015.ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448.doi:10.l 128/JVI.03274-1426. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R.Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to InfluenzaVirus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.18827. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Cells: So1iing and Regulation of the Na+,K+andH+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 0002320028. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci.2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 908215429. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of ProtonNIH-001969Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-930. El Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precisionmedicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835From :Sent :To:Subj ect :Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 12:52:45 +0000Conrad, Patricia (NIH/NIAID) [ElRE: WTOP RequestOK by me. Please set it up.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Conrad, Patricia (NIH/NIAID) [ElSent : Tuesday, February 11, 2020 7-:3-7- A-M- ---, .....,....,= To: Fauci, Anthony (NIH/NIAID) [El- -------- (b)(6) Subject : Fwd: WTOP Request1040 before you depart for aspen event?Sent from my iPhoneBegin forwarded message:From: "Chesson, Joslyn" <jchesson@wtop .com>Date: February 11, 2020 at 7:16:26 AM EST(b)(6)>To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -(,b;;)~- (=6)>Subject : WTOP RequestGood morning,Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss thecoronavirus and the quarantining on cruise ships.We have 10:40a, 11:lOa, and 12:10pm all open .NIH-001973NIH-001974Let me know if any of those times work for him!Thanks,Joslyn ChessonEditorWTOP News(202) 895-5060From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 12:20:02 +0000To: Lisa MonacoSubject : RE: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease aNational Security Priority - LawfareLisa:Thanks for the note and for sending this. Very ruce piece! I hope that all is well with you. I miss very muchour interactions.Best regards ,TonyAnthony S. Fauci , MDDirectorNat ional Institute of Allergy and Tnfectious DiseasesBui lding 31, Room 7A-0331 Center Drive, MSC 2520National In stitutes of HealthBethesda, MD 20892-2520Phone: (b) (6)FAX: (30 I) 496 -4409E-mail (b) (6)The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. Itshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox or any other storage de vices. The National Institute ofAllergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's ownand not express ly made on behal f of the NIAID by one of its representatives.-----Orig inal Message-----From: Lisa Monaco _______ ..(."b,~"..('.6=, )Sent: Monday,febrnary 10, 2020 8:09 PMTo: Lisa Monaco (b)(6)Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - LawfareIn case you missed this, my latest on the coronovirus.https:/lwww.lawfareb log.com/co ronavirus -shows-whv-us-must-make -pandemic-disease -national-security-prioritySent from my iPadNIH-001975From: Fauci, Anthony (NIH/NIAIO) [E)Sent: Mon , 10 Feb 2020 22:44:53 +0000To: Routh, Jennifer (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy(NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E]Subject: RE: for review: responses for Washington TimesAtt achment s: responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docxSee my tr acked changes in at tached document . Thanks.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It shou ld not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Routh, Jennifer (NIH/NIAID) [E]- -------- (b)(6) Sen t : Monday, February 10, 2020 4-:0-7 -P-M- - ::;..,..-,= To: Fauci, Anthony (NIH/NIAID) [E]~ ======(~bH~ > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E)(b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea(NIH/NIAID) [E_ ______ C_>b<6JF olkers, Gre"g" -(:N--I:H--/N"'"I"A"I'D.")' -[:E-:]-_ :_:-_=_=_:_::_: :.:...--,.;_-=-Cc_-Hbc_6-=)>-tSubject: for review: responses for Washington TimesDr. Fauci -The reporter Shen Wu Tan from the Washington Times reached out to us this morning with somequestions about 2019-nCoV. I drafted proposed responses to these questions with input from Andrea.Please see attached. Please let me know if you have edits . I will send the final responses back to thereporter, and I will note they are attributed to you .Thanks,JenJennifer Routh [E]News and Science Writ ing BranchOffice of Communications and Government RelationsNIH-001980National Institute of Allergy and Infectious Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda, MD 20892Direct: Cb()6 )CbHDisclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not beused by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete iifrom your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives.NIH-001981From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 10 Feb 2020 20:22:28 +0000Routh, Jennifer (NIH/NIAID) [E]Subject:coronavirus?FW: Wpost : Q&A with Anthony Fauci: Are we past the point of containment forLet us discuss.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBui lding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sen sitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e -mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Folkers, Greg (NIH/NIA ID) [E) -------- (b) (6)> Sent : Monday, February 10, 2020 2:37 PMSubject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus?OpinionsQ&A with Anthony Fauci: Are we past thepoint of containment for coronavirus?NIH-001982man wears a protective mask while walking inWuhan, China, on Feb. 10. (Stringer/AFP/Getty Images)ByRobert GebelhoffAssistant editor and Opinions contribu torFeb. 10, 2020 at 2:22 p.m. ESTThe latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsingthe body count from Chino's SARS outbreak in 2002 and 2003 .To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5.Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at theNational Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity andbrevity .Robert Gebelhoff: Right off the bat, what makes this virus different?Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to usea big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no realunderlying experience with it, so the general population is naive with regard to protection . And it hasserious potential, because it's already spreading rapidly . It's the unknown aspect of something thatalready tells you it's a serious problem. We don' t know where it's going.Gebelhoff : Are we past the point of containment for this coronavirus?Fauci: No, we're not. The short answer is we're not past the point of containment. But it really doeshave the potential to turn into a global pandemic . What we have now is a very serious epidemic inChina .. .. [But outside of China,] there is very little - but some - transmission from person to person .Once you get mult iple countries that have sustained transmission from person to person, then it 'sbeyond the situation where you can contain it. You can only mitigate it.In the United States, we are clearly in the containment phase .... And what we've done is we'veidentified . We've isolated . And we've done contact-tracing [identifying who might have come in contactwith an infected person]. That seems to be successful. But once it it starts spreading all over the world ...then it's almost inevitable that it's going to start spreading here .Gebelhoff : The Post reported last week that China withheld information from the public, includingsilencing medical professionals, and that this made the spread of the virus worse. How does the UnitedStates work with a governm ent that we can't even trust to tell the tru th to its people?NIH-001983Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people -CDC, NIH people - there on the ground , both helping and seeing with their own eyes exactly the extentof this. We want to be part of a [World Health Organization] convening group that goes there. But thusfar, we've not been able to make that a reality.Gebelhoff: And why's that?Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we'vedealt with for years if not decades. Many of them have trained in the United States. And we know themas friends and as colleagues. They are the ones that are not holding back .... But they're not the onesthat make the official proclamations of what comes out. The solution to the problem in the questionyou're posing is that we really do want people there, so that we can not only help them but also providesome expertise that might supplement or complement their own expertise.Gebelhoff: What does the United States do if [the coronavirus] does become a pandemic in thedeveloping world?Fauci: Well obviously we will try to help them to contain as best as possible .... Right now, by definition,it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount ofsustained transmission outside of China is still minimal. ... But there are some countries where it is goingto be very difficult to stop the evolution into sustained transmission. Obviously the [World HealthOrganization] and the global security network that we put up over the years will try to help thosecountries, but there's no guarantee that we'll be successful.Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around theworld as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma."WhatFauci: Everyone agrees that travel bans and restrictions are almost never successful In completelystopping something is that invariably going to turn into a pandemic .... What we are trying to do is topause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becomingglobal and to give us a little more time to prepare. There's no indication or imagination that if thisbecomes a global pandemic that travel restrictions are going to mean anything . But they can meansomething , as a temporizing activity.Gebelhoff : What should the average person be doing right now about coronavirus?Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk canchange, so pay attention to what's going on [and] to the ... announcements coming from the CDC. ... Thethings that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactlythe same things that you would do if we did get coronavirus here. So the question is, should we doanything different from what we're already doing? No. Should we all be wearing a mask? Absolutelynot.Read more:The Post's View: The virus that shook China's systemChen Guangcheng: Warning: Chinese authorit arianism is hazardous to your healthDavid Ignatius: The coron avirus out break shows the vulnerability of t he 'Chinese model'John M. Barry: Can th is virus be contained? Probably not.John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peopleRobert GebelhoffNIH-001984NIH-001985Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since2015 .FollowDisclaimer : Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily representmy views nor those ofNTATD, NTH, HHS , or the U.S. governme nt.From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 10 Feb 2020 20:18:24 +0000Billet, Courtney (NIH/NIAID) [E]Subject: FW: Potentia l Treament Strategy to Reduce Motality Caused by CoronavirusInfectionNIAID inquiries, PleaseAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: (b)(6) ----------------- Se nt: Monday, February 10, 2020 3:02 PM ------~~ = To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: Potential Treament Strategy to Reduce Motality Caused by Coronavi rus Infectio nDear Dr. Fauci:One effect ive way to get th ings done is through the individuals like you at the frontline with authorities .I know that you are very busy, and I am sorry to bother you. You probably already knew what I'm goingto say and appear to be so relaxed.With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbasedimmunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal causefor t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icleentitled " Extending the Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms ofAction of Photopheresis" and ot her related arti cles on this topic .Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinicaldata support this motion , which include : (1) ozone therapy ( withdraw about SO ml -100 ml bloodfrom patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ientin 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuumseffec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order toreinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at theNIH-001986NIH-001987period of fever, viremia stage. These simple approaches can be incorporated with the other medicaltreatments and support ive care.I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this emailand providing your insight as well as help.Sincerely,Ching Y. Voss, M.D.From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon, 10 Feb 2020 20:10:11 +0000Conrad, Patricia (NIH/NIAID) [ElSubject: RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DCSorry. Cannot do. Congressional Hearin g.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Zev Moses <zev.moses@usasiainstitute .org>Sent : Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E)- ------~~ CbH6)>F; auci, Anthony (NIH/N IAID) [E)-------- CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DCGood afternoon,The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event onFebruary 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation isattached.This event will focus on the public health impacts of the novel coronavirus, the facts on the ground,trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staffon these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci'scurrent research is vital to support ing productive and informative dialogue.Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in thisevent. We would be honored to host him or others from NIAID and our audience would be extremelyinterested to learn from your agency's research.Sincerely,Zev MosesNIH-001988NIH-001989Zev Moses I Director , International & Government AffairsUS-Asia Institute232 East Capitol St. NEWashington , D.C. 20003202-544-3181www.usasiainstitute.orgFrom:Sent:To:Subject:Washington, D.C.Atta chments:Fauci, Anthony (NIH/NIAIO) [E)Mon, 10 Feb 2020 19:19:42 +0000Conrad, Patricia (NIH/NIAID) [E)FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting inDr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdfLet us di scuss. We do not need to bring befo re th e OD AM grou p. I wo uld like todo t his if possible. It is an invitat ion f rom Meghan O'Sullivan who was one of thesecur ity crew fr om Bush 43.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Richard Fontaine <rfontaine@trilateral.org>Sent: Monday, February 10, 2020 11:30 AMTo: Fauci, Anthony (NIH/NIAID) [E)_ _____ (=b)'"("=6' )>Cc: Meghan O'Sullivan (b) (6) Torrey Taussig <ttaussig@tr ilateral.org>Subject: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Washington, D.C.Dear Dr. Fauci,The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., onMarch 13-15, 2020. I would like to invite you to participate in a conversation at the meeting onresponding to the coronavirus and global pandemics .As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think throughthe shared challenges and leadership responsibi lities of the three principal industrialized democraticareas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes itsoriginal mission of bring ing democrat ic countries together to tackle international challenges should onceagain be a majo r priority for our country and our partners . This year's plenary meeting is a major, three daygathering of our global membership during which we will explore the theme "Democracy andCapitalism at a Crossroads."NIH-001990NIH-001991Your participation would make a great difference if you are available. Attached to this email you will findan invitation from North American chair Meghan O'Sullivan. Please do let us know if you have anyquestions about the event or your potential role in it, and we hope that you are able to accept ourinvitation .Best wishes,RichardRichard FontaineExecutive DirectorTrilatera l Commission - North AmericaFrom:Sent:To:Cc:Subject :Eric:Fauci, Anthony (NIH/NIAIO) [E)Mon , 10 Feb 2020 18:52:31 +0000Strauss, Eric M.Conrad, Patricia (NIH/NIAID) [ElRE: Heat kills novel CoronavirusThe following is all on background. Coronaviruses in general tend to circulateand infe ct predominantly in the winter season {Northern and Southernhemispheres have opposite seasons). We do not know for sure why th is is thecase; however , many believe that the enclosed spaces in winter {mostly indoorbecause it is cold) allows better spread of a respiratory borne virus. Also, someviruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather.Remember, however, that when it is summer here , it is winter in Australia andArgentina . This may be the genesis of the information given to President Xi andPresident Trump that the virus may "go away" in the warm weather. However ,this is a brand new virus with which we have no pr ior experience and it is entirelyconceivable that seasonal changes will not have any impact on the spread.Hope t hat this is helpful.Best,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520Nationa l Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301 496-4409E-mail : (b)(6]The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended rec ipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Strauss, Eric M.<Eric.M.S tr auss@abc.com>Sent: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>Subject: Heat ki lls novel CoronavirusNIH-001992NIH-001993Dr. Fauci:We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medicallysound?Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and theChinese president told him "the heat generally kills this kind of virus."The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talkingabout having to do a lot of people. We think that goes away in April with the heat," he said.Eric M. Strauss, ABC NewsManaging Editor, Medical Unitwww.ericmstrauss .comPhone: 212-456 -2016Connect on Social: T/1/F = @ericMstraussFrom:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 10 Feb 2020 18:08:29 +0000Jon LaPookSubject:Attachment s:FW: "Coronavirus is airbo rne, Chinese official confi rms"Amoy Gardens and SARS.pdfJon:Thanks for the note. See attaclunent for our future discussion.Best,TonyAnthony S. Fauci , MDDirectorNat ional Institute of Allergy and lnfoctious DiseasesBuild ing 31, Room 7A-0331 Center Drive , MSC 2520Nat ional In stitutes of Hca llhBethesda , MD 20892-2520Phone: (b)(6)FAX: (30 I) 496-4409E-mail: (b)(6)The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . Itshould not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox or any other storage de vices. The National Institute ofAllergy and Infectious Diseases (NlA lD) sha ll not accept liability for any statements made that are the send er's ownand not express ly made on behalf of the NIAID by one of its represe ntatives.-----Orig inal Message-----From : Jon LaPook ,.::;....---~ (~b)~(=6)>Sent: Monday , febrnary 10, 2020 10:0-8- A--M- -~-= To : Fauci, Anthony (NlH/NIAID) [E) (b)(6) >Cc: amb@cbsnews.com ; Kev in Finnegan <kpf@cbsnews.com >; Alturo Rhymes <RhymesA @cbsnews.com >; JayShaylor <Shaylor@cbsnews.com >; CBS LaPook <lapoo]tj@cbsnews.com >Subject: "Coro naviru s is airborne, Chinese official confirm s"Hi To ny,I need a Fauci brain dump.You may have seen this:https :/fwww .nzherald .co . nz/wor ld/news/ articl e.cfm?c id=2&objecti d= 12307276Is this news? Don' t we already know that the virus spread via droplet transmission? This article says aerosoltransmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha tmakes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infectsome body 2 hours after some body with measles leaves the room.Tomorrow, I wi ll be giving an hour and a half of affiliate debriefings on this virus. So we wi ll be reaching mill ionsof people. I'd love to get the latest and greatest public health message . Incidentally, Howard Zucker and theinfect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ientswho have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they havecoronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms toget wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowherein the n ear future , right?NIH-001998NIH-001999Thanks,JonJonathan LaPook, M.D.Chief Medical Corresponde nt, CBS NewsProfessor of MedicineNYU Langone HealthTwitter @DrLaPookFrom:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 10 Feb 2020 12:54:14 +0000Sciutto, JimSubject: RE: Long time, no see!Jim:Thanks for the note . All is well here except that I am not getting much sleep -coronavirus 24/7. I look forward to being on your show.Best regards ,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made t hat are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Sciutto, Jim <Jim.Sciutto@cnn .com>Sent: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------~-=- -- (b)( > Subject: Long time, no see!Glad to have you on the show today. Looking forward. Hope all is well. JimJim SciuttoNewsroom Anchor & Chief National Security CorrespondentCNNEmail: jim.sciut to@cnn.comMobile : ___ (b)( 6YTwitter: @jimsciuttoNIH-002002From:Sent :To:Cc:Fauci, Anthony (NIH/NIAID) [E)Mon, 10 Feb 2020 11:18:00 +0000Conrad, Patricia (NIH/NIAID) [E)Awwad, David (NIH/NIAID) [CJSubject: FW: REQUEST FOR A TV INTERVIEW ON WION TV INDIAWe did this before, but we cannot do it at 7:30 AM (b)(6) Ifthey want to do it later in the day and we can fit them in, then fine. If not, that is OK too. Notthe highest prior ityFrom: Latika Chugh {WION) <latika.chugh@zeemedia.esselgroup.com>Sent: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El------- (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ(b)(6)>; Oplinger, Anne {NIH/N IAID) [E] (b)(6); Richa Sharma --------- ( W 10 N) <Richa.sharma@zeemedia.esselgroup .com>Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIADear Anthony S. Fauci,M.D., NIAJD DirectorGreetings from WION!I would like to request for your time for an interv iew with us today for 10-15minutes at 7:30 am Monday, in Maryland , USA via Skype.It's regarding the upd ate in the story of Coronavirus -The World HealthOrganization chief says there have been 'c oncerning instances' of onwardtransmission of coronavirus among people who hadn't been to China.Waiting for your confirma tion.CLICK HERE TO WATCH WION LIVE :NIH-002003https://www.wionews.com/live-tvLive TV, News I wionews.com© 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved.www.wionews.comLook forward hearing from you .RegardsLatika ChughWION TV , IndiaFrom: Awwad, David (NIH/NIAID) [CJ- -------- (b) (6)> Sent : Thursday, February 6, 2020 6:41 PMTo: Latika Chugh {WION) <lat ika.chugh@zeemed ia.esselgroup.com>; KUMAR SUNNY<KUMAR.SUNNY@zeemedia.esselgroup .com>Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) 1>; Barasch, Kimberly (NIH/NIAID ) [CJ---------- (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) <Richa.sharma@zeemed ia.esselgroup .com>Subject: RE: REQUEST FOR A TV INTERVIEW ON WION TV INDIAOur pleasure. Thank you again.DavidDavid Awwad, ContractorCustomer Services Branch, NIH\NIAID\OCICBNTT DATA Services Federal , LLCPhone : (b) (6)(b)(6)Disclaimer :NIH-002004The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient. If you havereceived this e-mail in error please inform the sender and delete it from your mailbox or any otherstorage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity for anystatements made that are sender's own and not expressly made on behalf of the NIAID by one of itsrepresentatives.From: Latika Chugh {WION) <lati ka.chugh@zeemedia.esselgroup .com>Sent: Thursday, February 6, 2020 8:06 AMTo: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY<KUMAR.SUNNY@zeemedia.esselgroup .com> -------~~ Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ---------- (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) <Richa.sharma@zeemed ia.esselgro up.com>Subject : Re: REQUEST FOR A TV INTERVIEW ON WION TV INDIADavid,Many thanks for the Interview.He really added value in our show.We look forward to have his presence in future on WION.RegardsLatika ChughFrom: Awwad, David (NIH/NIAID) [C] (b)(6)Sent : Thursday, February 6, 2020 5:00 PMTo: Latika Chugh {WION) <lat ika.chugh@zeemed ia.esselgroup.com>; KUMAR SUNNY<KUMAR.SUNNY@zeemedia.esselgroup.com>Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ(b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1>; Richa Sharma _______._.... _{WION) <Richa.sharma@zeemed ia.esselgroup.com>Subject: RE: REQUEST FOR A TV INTERVIEW ON WION TV INDIAThank you much.From: Latika Chugh {WION) <lat ika.chugh@zeemedia.esselgroup.com>Sent : Thursday, February 6, 2020 6:29 AM -------~ = To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY<KUMAR.SUNNY@zeemed ia.esselgroup. com>Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ---------- (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) <Richa.sharma@zeemed ia.esselgroup .com>Subject: Re: REQUEST FOR A TV INTERVIEW ON WION TV INDIANIH-002005Dear David,It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 minutes onlyon Skype.My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now.Also, We have send you Skype Request from WION Skype Id some hours ago. I request you toplease add us.RegardsLatika ChughFrom: Awwad, David (NIH/NIAID) [CJ Cb)(Sent: Thursday, February 6, 2020 4:54 PMTo: Latika Chugh (WION) <lat ika.chugh@zeemedia.esselgroup.com>Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID) (Cl---------- (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUEST FOR A TV INTERVIEW ON WION TV INDIALet me know if you would like to connect a couple minutes earlier. I am on standby .David-----(b)(6) (cell)David Awwad, ContractorCustomer Services Branch, NIH\NIAID\OCICBNTT DATA Services Federal, LLCPhone: Cb) (6)(b)(6)Disclaimer:The information in this e-mail and any of i ts attachments is confidential and may conta in sensitiveinforma t ion. It should not be used by anyone who is not the original intended recipient. If you havereceived this e-mail in error please inform the sender and delete it from your mailbox or any otherstorage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not expressly made on behalf of the NIAID by one of itsrepresentatives.From: Latika Chugh (WION) <lat ika.chugh@zeemedia.esselgroup.com>Sent: Wednesday, February 5, 2020 9:25 AM -------oc-c- = To: Awwad, David (NIH/NIAID) [CJ" .":=:=======~~ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID) [CJNIH-002006--------- Cb)( ,>; Oplinger, Anne (NIH/NIAID) [E] --------- (b)(6) Subject: Re: REQUEST FOR A TV INTERVIEW ON WION TV INDIAThanksSee you tomorrowLatika : (b)(6) ------Get Outlook for AndroidFrom: Awwad, David (NIH/NIAID) [C] --------- (b)(6)Sent : Wednesday, February 5, 2020 7:50 :26 PMTo: Latika Chugh (WION) <lat ika.chugh@ zeemed ia.esselgroup .com>Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) [CJ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6)Subject: Re: REQUEST FOR A TV INTERVIEW ON WION TV INDIASkype Handle: Live:niaidithelp or niaidit help@outlook.comDavid: (b)(6)Sent from my iPhoneOn Feb 5, 2020, at 9:16 AM, Latika Chugh (WION)<latika .chugh@zeemedia .esselgroup.com> wrote:Yes,It completely fine with us.Our Skype Id - wion record. Please share your Skype id with us.We will be online at 7 AM ET TIME WHICH WILL BE 5:30 PM OUR TIME IN 1ST.RegardsLatika ChughProducer , WionIndiaFrom: Conrad, Patricia (NIH/NIAID) [E] --------- (b)(6)Sent: Wednesday, February 5, 2020 7:35 PMTo: Latika Chugh (WION) <latika .chugh@zeemed ia.esselgroup .com>Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, DavidNIH-002007(NIH/NIAID) [C) (b)(6J>; ,,;__;_ _ __;..;:_;.::::=:,;: (b:):(:c:6=:):>:- ____ _ Oplinger, Anne (NIH/NIAID) [E]Subje ct: FW: REQUEST FOR A TV INTERVIEW ON WION TV INDIADr. Fauci can do a skype int erview Thursday morn ing 7 am - 7:15 am ETby skype. Please let us know asap if that wo rks.Patricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. Itshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergyand Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nt made that are sender's own and notexpressly made on behalf of the NIAID by one of its representat ives.From: Latika Chugh {WION) <lat ika .chugh@zeemed ia.esselgroup.com >Sent: Tuesday , February 4, 2020 5:15 AM -------=-c-c= To: Fauci, Ant hony {NIH/NIAID ) [E] (b)(6)>Cc: Wion Guest Relations <wion.guestrelations@zeemedia.esselgroup.com>Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIADear Anthony S. Fauci,M.D., NIAID DirectorGreet ings from WION!World Is One News (WION)is an internat iona l English news channel from the ZeeMedia Group, India's premier television brand. WION is uniquely positioned as the'Global Voice of India', present ing its own perspective on international issues ofcritical significance. WION is the prefe rred channel for most opinion makers acrossthe wor ld as they happi ly attend our shows bringing in credibleviewpoints on many issues. WION is currently available in India, Indones ia, TheRepublic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia ,Singapore and South Africa etc.NIH-002008NIH-002009WION's shows have featured Indian Political scenario & global leadersspeaking on issues facing their country and the world in general.I would like to request for your time for an interview with us anytime soon todayfor 10-15 minutes. We usually conduct Interview via Skype. Request you to shareyour Skype Id.It's regarding CORONAVIRUS.Please let us know when is the best time for you to join us via Skype. Wait ing foryour confirmation.CLICK HERE TO WATCH WION LIVE :https://www .wionews.com/live -tvLive TV, News I wionews.com© 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved.www.wionews .comLook forward hearing from you .RegardsL atik a ChughWION TV , IndiaZee Disclaimer: Confidentia lity/ Proprietary Note: This communication is confidentia l/proprietary and is intended for use only by the addressee. Zee Media Corporation Ltd.accepts no responsibility for any mistransmission of, orinterference with , th iscommunicationFrom:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon, 10 Feb 2020 00:49:33 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: RE: CNN Interview CONFIRMATION: Dr. Anthony FauciThanks.From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)Se nt: Sunday, February 9, 2020 7:46 PMTo: Fauci, Anthony (NIH/NIAID) [E]-------= (b-)c(c-6-)=Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony FauciSent from my iPhoneBegin forwarded message:From: "Griffin, Janelle" <Janelle.Griffin@turner.com >Date: February 9, 2020 at 5:54:23 PM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID)[El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6),"Greene, Nyja" <Nyja.Greene@turner .com>Subject: CNN Inte rview CONFIRMATION: Dr. Ant hony FauciHello,We're all set for tomorrow! QDr. Fauci is confirmed for a live segment at 10: I Sa et on Newsroom w/Poppy Harlow & JimSciutto.Please ensure he 's seated no later than 10:0Sa et. (the show is aware that Dr. Fauci has ahard at 10:20a et)Nyja Greene , cc' d on this email , will be your Atlanta based show point of contacttomorrow.Any issues or changes please don 't hesitate to reach out to her in the morning.Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered theSARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, howbad do think this could become? How does the Coronavirus comp are/contrast with otherslike Ebola or Zika? How effective are quarantine s in situations like this? What, if any,precautions shou ld we be taking right now in America? Any thoughts /talking points you cansend ove.r from Dr. Fauci evening would be super helpful.NIH-002010Patrici a- thank you sooo much for all of your help with organizing. We really appreciate itand look forward to Dr. Fauci jo ining the show.From: Conrad, Patricia (NIH/NIAID) [E] CbH >Sent: Saturday, February 8, 2020 1:04 PMTo: Griffin, Janelle <Janelle.Gr iffin@turne r.com>Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El---------(b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony FauciOk thxSent from my iPhoneOn Feb 8, 2020, at 12:54 PM, Griffin, Janelle <Janelle.Griffin@turner .com>wrote:Great- thank you!Let's keep things for a segment at 10:lSa on Monday .I'll be back in touch after my 6p show planning conference call Sundayevening.Thank so much Patricia QFrom: Conrad, Patricia (NIH/NIAID) [El- -------- (b)(6) Sent : Saturday, February 8, 2020 12:53 PMTo: Griffin, Janelle <Janelle.Griff in@turner.com >Cc : Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer(NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E],,;_ ___ ;_;_.;..:::(:b?~H;;;;>-------Subject: Re: CNN Interview Request: Dr. Anthony FauciWe can make the 9 am hour wo rk too. Pis let us know ASAP so I can makesure our studio is available. When wi ll you have a final answer?My cell is ____ Cb_>C_6 ) and am always on email which is better for me.Sent from my iPhoneNIH-002011On Feb 8, 2020, at 12:48 PM, Griffin, Janelle<Janelle.Griffi n@turner .com> wrote:That's great- thanks Patricia !We'll add him to our calendar for 10:lSa et.If we needed to move him his segment to the 9a et hour wouldthat also work?May I have your cell number for my records?From: Conrad, Patricia (NIH/NIAID) [E](b)(6)>Sent: Saturday, February 8, 2020 12:46 PMTo: Griffin, Janelle <Janelle.Griffi n@tu rner .com>Subject: Fwd: CNN Interv iew Request: Dr. Anthony FauciHi JanelleWe can make this work - it would need to be from between 10am - 1020 am hard stop.Will that work?It wou ld need to be from our NIH Readycam studio withVideol inkLet me know if that worksFrom: Griffin, Janelle<Janelle.Griffin@turne r.com>Sent: Saturday, February 8, 2020 11:33 AMTo: Fauci, Anthony (NIH/NIAID) [E](b)(6)Subject: CNN Interview Request: Dr. AnthonyNIH-002012NIH-002013FauciImportance: HighGood morning Dr . Fauci ,I hope this email finds you doing well .I'm reaching out on behalf of Newsroom w/PoppyHarlow & Jim Sciutto hoping you can join for aninterview .Are you available to join CNN this MondayFebmary lOth in the 10a et hour?This would be live for about 5-7 minutes to discussdevelopments regarding the coronavirns.Please feel free to contact me via email or at (404)452- 7769 to let me know.Thanks for your time - I look fo1ward to hearingfrom you soo n.Janelle Griffin-ButtsEditorial Producer, CNNEmail: janelle .griffin@turner.com I Twitter:@janellegCNNFrom:Sent :To:(b)(6)Sun, 9 Feb 2020 16:36:38 -0500autotell ISubject: Re: Help Re: Novel Rx for CoronavirusThanks, Andy.Best regards,TonyOn Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote:Thank you my friend, hope it leads to something good for patients and the public .I was at a meeting of the "Philosophical Society of Texas" this week end and meet with alot of Bush alums like Don Evans and Margaret Spellings etc and Margaret wascommenting on the coronavirus scare and how fortunate we are to have you there at NIHlooking after us!! If you ever decide to relocate to Texas you have a fan club here!All my bestAndyFrom: Fauci, Anthony (NIH/N IAID) [E]- ------- (b)( > Sent: Sunday, February 9, 2020 7:24 AMTo: autotell I CbC) >Subje ct: RE: Help Re: Novel Rx for Coronav irusAndy:Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it bythe peop le here at NIAID who are r unning the nCoV research initiative. I will getback to you with their and my assessment. I hope that all is well with you. We aredoing a lot of late nighters here . Feels like my internship. DDBest regards,TonyFrom: autotell I Cb)( >Sent: Friday, February 7, 2020 2:50 PM ------~= To: Fauci, Anthony (NIH/NIAID} [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E)(b )( 6) >Cc: Xiaokui Zhang--------(b)(6) >; Robert Hariri(b)(6)>Subject : Help Re: Novel Rx for CoronavirusTonyNIH-0020 19Greetings . Always proud to see you at the White House (with Alex) leading the fightagainst th is latest infect ious disease threat (b)( 4)(b) (4)I trust this email finds my Paisano happy and content as you cont inue to be a gift to thisnation and the world. Please let me know you received this email.My best to you and your family . Hope our paths cross soonAndyNIH-002020From:Sent :To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 2020 18:23:24 +0000Folkers, Greg (NIH/NIAID) [E]RE: lnvestigational compound remdesivir, developed by UAB and NIHresearchers, being used for treatment of novel coronavirusWOW! I did not know that. Good talking point for press conferences.From: Folkers, Greg (NIH/N IAID) [E) (b)(6)Se nt: Sunday, February 9, 2020 1:13 PMSubject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used fortreatment of novel coronaviruslnvestigational compound remdesivir, developed by UAB andNIH researchers, being used for treatment of novelcoronavirusby Savannah Koplon• February 07, 2020• Print• Email___ --- - ,Richard Whitley, M.0., Distinguished Professor at UAB and principal investigatorof the U19 grantThe investigationa l drug remdesivir, developed through research conducted through the Ant iviral DrugDiscovery and Development Cent er, or AD3C, and centered at the University of Alabama at Birmingham,is being used to treat select infected patients in the United States and in China who have been affectedby the outbreak of novel coronavirus (2019-nCoV).UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Instit ute of Allergy andInfectious Diseases Centers of Excelle nce for Translat ional Research to study and develop treatment forhigh-priority emerging infections. Work has been taking place in earnest to develop drugs for emerginginfluenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARS and MERS, andalphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi -NIH-002021NIH-002022institutional collaboration to accelerate drug discovery for these emerging infections and is a publicprivatepartnership between academic institutions and Gilead Sciences.Remdesivir, developed to treat the coronavirus causing MERS, was found to have significant activ ityagainst the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly,remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS andSARS in cell culture and animal models . Based on the compassionate plea requests of treating physiciansin the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug hasnot yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety andefficacy studies is a major accompl ishment for the AD3C - namely the U 19 grant - as it shows significantand swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreakson an international scale and, importantly, to anticipate the introduction of these infections in theUnited States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator ofthe U19 grant.WATCH: UAB inf ectious disease experts prov ide info rmat ion on the 2019 novel coronav irus.Gilead Sciences and supporting researchers and clinicians are working with health authorities from theWorld Health Organization and in China to establish a placebo-controlled study to determine whetherremdesivir is safe and effective in treating 2019-nCoV."This is a prime example of how the research weare conducting at UAB plays a critical role intreating patients on a global scale and ourcontribution of substantial scientific advances."- Richard Whitley, M.D., UAB DistinguishedProfessor"The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and theUniversity of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of ourcollaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwidefight 2019-nCoV. This is a prime example of how the research we are conducting at UAB plays a criticalrole in treat ing patients on a global scale and our contribution of substantial scientific advances,"Whitley continued .Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partnerswi ll need to build backup molecules for potential testing and treatment in the near future.The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency ofinternational concern ."UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experiencedin virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease fromUAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , TheUniversity of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, theUniversity of Colorado, Denver, and Oregon Health & Science University.Disclaim er: Any third-party material in this email has been shared for internal use under fai1· use provision sof U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily representmy views nor those of NIAID, NIH, HHS, or the U.S. gover nment.From:Sent :To:Cc:Subject:Attachme nts:Liz:Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 2020 18:20:45 +0000Liz SzaboConrad, Patricia (NIH/NIAID) [E]RE: Plumbing as possible means of spread of coronavirusesAmoy Gardens and SARS.pdfThanks for the note . I do not know enough about the plumbing system on the cruise ships tomake any meaningful comments, certain ly not any comments that could be att ributable tome. And so, I will pass on this one, The best person to comment or opine on this would beMart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the originalNEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS.Best regards,TonyFrom : Liz Szabo <LSzabo@kff.org>Sent: Saturday, February 8, 2020 7:21 PM ------ ~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: Plumbing as possible means of spread of coronavirusesHI Dr. Fauci,I hope you're doing well. I know you must be very busy.Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might bespreading through plumbing on the cruise ship? She sent me these links, below, about howplumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in HongKong. Libby lived in China during the SA.RS outbreaks and remembers that the sinks there don'thave the typ ical U-bend trap that sinks have here, which allows sewer gases and unpleasantodors to come through.If plumbing is a risk for spreading coronavimses, what could be done to protect passengers oncruise ships?T'd love to hea r your thoughts on this, even if just by email.Thanks for your time.Liz SzaboKaiser Health News571-201-9009https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/NIH-002023NIH-002024https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm lhttps://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-diseasehttps:/ /jamanetwork .com/journals / jama/fullarticle /27 61044 ?guestAccessKey=f6 l bd430-07 d8-4b 86-a 7 49-bec05bfffb65&utm source=For The Media&utm medium=referral&utm campaign =ftm links&u tm content=tfl&utm tenn =020720From: Fauci, Anthony (NIH/NIAID) [E)Sent : Sun, 9 Feb 2020 17:59:10 +0000To: Tabak, Lawrence (NIH/OD) [E)Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia(NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea(NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6))Subject: RE: NCATs request re. CoronavirusLarry'-: -------------------------------, ("b~'"("S')Best,TonyFrom: Tabak, Lawrence (NIH/OD) [E) --------- (b)(6)> Sent: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID). .[E;l; ...;.:...:::==(=b)(=6) :~=----- Cc: Schwetz, Tara (NIH/OD) [El --------- (b)( > Subject : NCATs request re. CoronavirusTon' '-------------------------------~ ~ (b) (5)Thanks,LarryNIH-002025From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 202017:53:04 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony FauciOK. Thanks.From: Conrad, Patricia (NIH/NIAID) [El (b)(6)>Se nt: Sunday, February 9, 2020 12:44 PMTo: Fauci, Anthony (NIH/NIAID) [E]-------= (b-)c(c-6-)=Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony FauciI am working on this.Sent from my iPhoneBegin forwarded message:From: "Varon, Sophie" <Sophie.Varon@turner.com >Date: February 9, 2020 at 12:30:31 PM EST -------~= To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Fauci, Anthony(NIH/NIAID) [El" (b)(6)Subject : CNN Anderson Cooper Full Circle Request- Dr. Anthony FauciHello Dr. Fauci and Patricia ,I hope you're both doing well.I'm reach ing out to see if Dr. Fauci could be available for an interview withAnderson Cooper on Monday for his CNN digit al program, Full Circle . Full Circleis an intere sting platform because it allows us to take live viewer questions . Thistaped interview would air on Tuesday at 5PM and Anderson could tape tomorrow inthe 4PM hour or after 5:45PM.The topic is of course the Corona virus.Thank you for considering this request!Sophie VaronEd itorial Producer , CNN AC360cell- (bHNIH-002026From:Sent :To:Subject :Fauci, Anthony (NIH/NIAID) [E)Sun, 9 Feb 2020 17:52:22 +0000Conrad, Patricia (NIH/NIAID) [E)FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony FauciIf we can do this, I would be happy to.From: Varon, Sophie <Sophie.Varon@turner .com>Sent: Sunday, February 9, 2020 12:30 PM -------~ = To: Conrad, Patricia (NIH/ NIAID) (E] --------- (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] (b)(6)Subject: CNN Ande rson Cooper Full Circle Request- Dr. Anthony FauciHello Dr. Fauci and Patricia ,I hope you're both doing well.I'm reaching out to see if Dr. Fauci could be ava ilable for an interview with Ande rson Coope r onMonday for his CNN digital program, Full Circle. Full Circle is an interes ting platform becauseit allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM andAnderson could tape tomorrow in the 4PM hour or after 5:45PM .The top ic is of course the Coronavirus.Thank you for cons idering this request!Sophie VaronEditorial Producer , CNN AC360cell (b)(6)NIH-002027From:Sent :To:Fauci, Anthony (NIH/NIAI0) [E)Sun, 9 Feb 202017:5 1:21 +0000Hall, Bill (HHS/ASPA)Subject: FW: CNNI Interview with Dr. Anthony Fauci,Bill:Th is link below is for an interview that I gave for CNN International this morning . As we allknow, it makes such a big difference when the interviewer knows the subject and asks goodquestions that this interviewer did. Would that they were all like her.Best regards,TonyFrom: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Sent : Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)>Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J>Subject: RE: CNNI Interview Request: Dr. Anthony Fauci,We are so glad to!Here is the clip https:ljwe .tl/t -BOkVJSyQVBAl I the best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [El- -------- (b)(6)> Sent: 09 February 2020 16:15To: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: Re: CNNI Interview Request: Dr. Anthony Fauci,My pleasure- so glad we could make it wor k. Please do send us the the video segmentBest,Patty .Sent from my iPhoneOn Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) <Joanna.Hynds@turner .com> wrote:Dear Mr Fauci,NIH-002028I just wanted to thank you for your accommodation at such short not ice for the earlierinterview. I do apologise for the miscommunication on my part.We really enjoyed having you on the show!Thanks too to Patricia, for helping coordinate this all at last minute.I hope you both have a great evening.Many thanks again for your patience and understanding.If you would like a video segment of your hit I will gladly send you it on request.Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [E] (b)(6)Sent: 09 February 2020 14:26To: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Cc: Pfeifer, Hazel <Hazel.Pfeife r@turner.com >; Lovejoy, Hannah (NE) <H ann ah.Lovejoy@ turner .com>; Fauci, Anthony (NIH/NIAID) [E] ------------=---c---=(-b)(6)> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci,Do you have the hit time and contact info please send ASAP.Sent from my iPhoneOn Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE)<Joanna.Hynds@turner .com> wrote:Perfect - we really appreciate this.I will get you these deta ils ASAP.Does Dr Fauci need a car?Best,JoannaNIH-002029From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)>Sent: 09 February 2020 13:33To: Hynds, Joanna (NE) <Joanna.Hynds@turner.com >Cc: Pfeifer, Hazel <Hazel.Pfeifer@turner.com >; Lovejoy, Hannah (NE)<Hannah.Lovejoy@turner.com >; Fauci, Anthony (NIH/NIAID) [E](b)(6)Subject: Re: CNNI Interview Request: Dr. Anthony Fauci,Adding Dr Fauci hereHe can come to the WDC CNN studio. Please send us the exact live hit time aswell as the studio address and on-site contact name, number and cell numberASAP. Dr Fauci cell is (b)(6)and you have mine.Thank you .Sent from my iPhoneOn Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE)<Joanna.Hynds@turner.com > wrote:Dear Patricia,Just following up from our phone conversation , unfortunately Iwon't be able to facilitate a StudioGo t ruck for this interview.We are still really keen to get Dr Fauci on the show-w ill he beable to come to the bureau?I will be able to book him a car if he needs.Let me know what suits,Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [E](b) ~ >Sent: 09 February 2020 13:00To: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Subje ct: Re: CNNI Interview Request: Dr. Anthony Fauci,NIH-002030For the t rick- the location is northwest Washington DC. NearAmerican university.Sent from my iPhoneOn Feb 9, 2020, at 7:51 AM, Conrad, Patricia{NIH/NIAID) [El (b)(6)> wrot e:Please call me ASAP at -----(b)(6)for this request.Sent from my iPhoneBegin forwarded message:From: "Fauci, Anthony (NIH/NIAID)[El" CbC) >Dat e: February 9, 2020 at 7:08:54AM ESTTo: "Conrad, Patr icia (NIH/NIAID) [E]"(b)(6)Subject: Fwd: CNNI InterviewRequest: Dr. Anthony Fauci,Sent from my iPhoneBegin forwarded message:From: "Hynds, Joanna(NE)"<Joanna.Hynds@turner.com>Date : February 9, 2020at 6:06:15 AM ESTTo: "Fauci, Anthony(NIH/NIAID) [El"(b)(6)>Cc: "Tejera, Isabel{Intern)"<isabel.Tejera@turner.com>, "Lovejoy, HannahNIH-002031NIH-002032(NE)"<Hannah.Lovejoy@turner.com>Subject: CNNIInterview Request: Dr.Anthony Fauci,Dear Dr Fauci,I hope you are well! Iam reaching out fromCNN International toenquire if you areavailable today to joinus on Connect theWorld at llaET todiscuss the coronavirus.Might this be apossibility? It would begreat to arrange this.Background on CNN• CNNInternationalreaches morethan 250millionhouseholdsworldwideincluding in theUS via DIRECTV.• CNNInternational isthe numberoneinternationalTV newschannelaccording to allmajor mediasurveys acrossEurope, theMiddle East andAfrica, the AsiaBest,Pacific regionand LatinAmeric a.• In September2019 CNN.comhad 162 millionunique readersglobally permonth and 114million mobilereaders amonth, leadingthe BBC, Yahooand New YorkTimes.Joanna HyndsPlanning DeskCNN Intern ation al+ 44 207 693 1640(office)+ (b)(6) ( cell)joanna.hynds@turner.com<image0O1.png>Information in thisemai l including anyattachments may beprivileged orconfidential and isintended exclusively forthe addressee. Theviews expressed maynot be official policy,but the personal viewsof the orig inator . If youhave received this emailin error, please notifythe sender by return emailand delete it fromyour system . Youshould not reproduce,distr ibute, store,NIH-002033NIH-002034retransmit, use ordisclose its contents toanyone. Please note wereserve the right tomonitor all e-mailcommunicat ionthrough our internaland external networks.Turner and the Turnermarks are trade marksof Turner BroadcastingSystem Inc and areused under licence.Turner BroadcastingSystem Europe Limited(Company No.1927955), TurnerEnterta inmentNetworks Internationa lLimited (Company No.2803512), TurnerBroadcasting SystemHoldings (Europe)Limited (CompanyNumber 2802926) andCable NewsInternationa l Limited(Company No.5001368) areincorporated in Englandand Wales and sharethe same registeredoff ice at Turner House,16 Great MarlboroughStreet, London WlF7HS.Information in th is email including any attachments may beprivileged or confident ial and is intended exclusively for theaddressee. The views expressed may not be official policy, butthe personal views of the or iginator. If you have received th isemail in error, please not ify the sender by return e-mail anddelete it from your system . You should not reproduce,distribute, store, retransmit, use or disclose its contents toanyone . Please note we reserve the right to monitor all e-mailcommun ication through our internal and external networks.NIH-002035Turner and the Turner marks are trade marks of TurnerBroadcasting System Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No.1927955), Turner Entertainment Networks Internat ional Limited(Company No. 2803512), Turner Broadcasting System Holdings(Europe) Limited (Company Number 2802926) and Cable NewsInternat ional Limited (Company No. 5001368) are incorporatedin England and Wales and share the same registered office atTurner House, 16 Great Marlborough Street, London Wl F 7HS.Informat ion in this email includ ing any attachments may be privileged orconfidential and is intended exclusively for the addressee. The viewsexpressed may not be officia l policy, but the personal views of the originator .If you have received th is email in error, please notify the sender by return emailand delete it from your system. You should not reproduce, distribute ,store, retransmit, use or disclose its contents to anyone. Please note wereserve the right to monitor all e-mail communication through our interna land externa l networks . Turner and the Turner marks are trade marks ofTurner Broadcasting System Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No. 1927955), TurnerEnterta inment Networks Internationa l Limited (Company No. 2803512),Turner Broadcasting System Holdings (Europe) Limited (Company Number2802926) and Cable News Internat ional Limited (Company No. 5001368) areincorporated in England and Wales and share the same registered office atTurner House, 16 Great Marlborough Street, London WlF 7HS.Information in th is email including any attachments may be priv ileged or confidentia l andis intended exclusively for the addressee. The views expressed may not be off icial policy,but the personal views of the originator. If you have received th is email in error, pleasenotify the sender by return e-mail and delete it from your system. You should notrep roduce, distr ibute, store, retransm it, use or disclose its contents to anyone. Please notewe reserve the right to monitor all e-mail communicat ion through our internal andexterna l netwo rks. Turner and the Turner marks are trade marks of Turner BroadcastingSystem Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No. 1927955), TurnerEntertainment Netwo rks Internat ional Limited (Company No. 2803512), TurnerBroadcasting System Holdings (Europe) Limited (Company Number 2802926) and CableNews Internat ional Limited (Company No. 5001368) are incorporated in England andWales and share the same registered off ice at Turner House, 16 Great Marlborough Street,London WlF 7HS.Informat ion in this email includ ing any attachments may be privileged or confident ial and is intendedexclusively for the addressee. The views expressed may not be off icial policy, but the personal views ofthe originator . If you have received this email in error, please not ify the sender by return e-mail andNIH-002036delete it from your system. You should not reproduce, distribute, store, retransmit , use or disclose itscontents to anyone. Please note we reserve the right to monitor all e-mail communication through ourinternal and external networks . Turner and the Turner marks are trade marks of Turner BroadcastingSystem Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment NetworksInternational Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited(Company Number 2802926) and Cable News International Limited (Company No. 5001368) areincorporated in England and Wales and share the same registered office at Turner House, 16 GreatMarlborough Street, London WlF 7HS.From:Sent :To:Subject :Fauci, Anthony (NIH/NIAID) [E)Sun, 9 Feb 2020 17:34:16 +0000Denise OberRE: HEART WRENCHING QUESTION! WillThe State Department and CDC travel alerts for China, which advise only absolutely essential travel, do notofficially include Hong Kong and so there is no official restriction right now (but this could change), and there is noquarantin e requir ement upon returning from Hong Kong. However, thi:; all could change quickly . (b)(6)-----Original Message-----From: Denise Ober ;;-- ------- (b~)~(=6)Sent: Saturday , February 8, 2020 3:23 -PM-- --- --:,,:,~ To: Fauci, Anthony (NIH/NIAJD) [E] -------- (b)(6) > Subject: HEART WRENCHING QUESTION1 WODear Dr. Fauci,l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busyand so very importantly needed at this time. I do apologize for taking even a moment from your high demandschedule. But thought I'd try to reach out anyway in case you did see this.l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge aboutthe coronavirus thus far if ou had lanned to travel to Thailand mid March via stop over at Hon Kono-would ou?Thank you from my concerned heart!Thank you for EVERYTHING you do and have done in the past!Best to you,Denise OberSent from my iPadNIH-002037(b)(6)From: Fauci, Anthony (NIH/NIAID) [ElSent: Sun, 9 Feb 2020 17:26:01 +0000To: Cassetti, Cristina (NIH/NIAID) [ElCc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers--------- (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E]Subject: FW: Help Re: Novel Rx for CoronavirusAttachments: __ C_b>_C_4) in 2019-CoV Proposal 07Feb2020.docxCristina :This is not jus t your ordinary person writing to us. This is Dr. Andrew von Eschenbach, formerDirector of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit;however, please have someone go over it carefully and put together a response. Also, only ifappropriate, and feasible, see if there is any way we can be of assistance to him. Th anks.Best regards,TonyFrom: autotell I ----------- (b)(6)Sent: Friday, February 7, 2020 2:50- P-M-- --~~ To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b )( 6)_Cc_: X_ia_ok_ui Zha.n.g.. ::.===~~------(b) (6) >; Robert Hariri ---------- (b )( 6)(b)(6)Subject: Help Re: Novel Rx for CoronavirusTonyGreet ings. Always proud to see you at the White House (with Alex) leading the fight against this latestinfect ious disease threat. Cb) (4)(b) (4)I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and theworld. Please let me know you received this email.My best to you and your family. Hope our paths cross soonAndyNIH-002038From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 202017:17:07 +0000Stover, Kathy (NIH/N IAID) [ElCc:(NIH/NIAID) [ElSubject:Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, GregRE: FOR ASF REVIEW: Draft responses to questions from Italian news agencySee my edits in red.From: Stover, Kathy (NIH/NIAID) [E] (b)(6)>Sent: Friday, February 7, 2020 2:02 PMTo: Fauci, Anthony (NIH/NIAID) [El------ (=b)'"("=6' )>Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E)---------- (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject : FOR ASF REVIEW: Draft responses to questi ons from Italian news agencyHi Dr. Fauci,Below are draft responses to questions from a reporter with the Italian news agency ANSA.Please let me know if you have any suggested edits, and I'll move it along.Thanks,KathyEnrica BattifogliaScience and Technology Head EditorANSA news agency (Italian news)Enrica .Batt ifogl ia@ansa .itExpected place of publication: ANSA Science web page (www .ansa.it/scienza )Dear Professor Fauci ,I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure tointerview you several times at the AIDS world conferences.I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on theANSA Science web page (www.ansa.it/scienza ), the main online science news resource in Italywith over 1.5M contacts each month. I am sure that your clarity and competence will be highlyvaluable to put some much-needed order among so many contrasting news and data, and wouldbe much appreciat ed by our readers .NIH-002039NIH-0020401. Do the current available data allow to understand the threat level of coronavirus 2019-nCoV in terms of both lethality and diffusion speed, and about the possible evolutionscenarios of the disease?There is much that we do not know about the novel coronav irus. Curre ntly, there have been morethan 37,000 confirmed cases in China, and China has reported more than 800 deaths. As youknow, there have been three confirmed cases in Italy to date. The reported case fatality rate(lethality) among the 37,000 cases that have come to the attention of the health care systemis 2%. However , given that there are likely many more cases that are without symptomsor with minimal symptoms, the actual death rate is probably lower than 2%.It is impossible to predict how the virus will evolve. It is our hope that the extraordinarycontainment measures that China has implemented will help prevent the outbreak frombecoming a global pandemic. But given that the virus is present in 27 countr ies to date and canbe transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic .2) What exactly do we know about its modes of transmission, especially from people whodo not yet have the symptoms?Again, there is much that we do not know about the novel coronavirus, including its specifictransmission abilities. Based on initial findings that have been reported, we suspect itstransmission is similar to influenza and other respiratory viruses, namely that is transm ittedthrough respiratory droplets when an infected person coughs or sneezes, and by touchingsurfaces, such as door handles, that recently have virus on them and then touching your face.There have also been reports that the virus is present in feces and vomit. However, it is stilluncertain that the virus can be transmitted through this route.Traditionally, most viruses are transmitted when someone has symptoms. With the novelcoronavirus; however, there appears to be asymptomatic transmission occurring. We do notknow how many cases are being driven by asymptomatic transm ission or by those withsymptoms . Typically, viruses are largely transmitted by infected peop le experiencing symptoms.3) Are the genetic sequences provided by China enough to start working on a vaccine?The genet ic sequences provided by China enabled researchers to quickly develop a diagnosticthat is being used to dete1mine whether someone is infected with the novel coronavirus. Thegenetic information has also been useful in work to develop a preventive vaccine. The NationalInst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, isbuilding on its experience with the SARS and MERS corona viruses to better understand the virusas well as develop and test rapid point-of-care diagnostics , vaccines and treatments, includingbroad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we areNIH-002041working with the biotechnolog y company Moderna and the Coalition for Epidemic PreparednessInnovation (CEPI) to develop a "messenger RNA" vaccine for the novel coronav irus. Othercountries and companies are working to develop a vaccine as well.4) What are the technical times to develop a working vaccine in terms of scientific research,and what are the approx times for the necessary legal certifications, and for industrialproduction and distribution?In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having anexperimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinicaltrial will involve administering the vaccine to a small number of healthy adults in the UnitedStates to see if it is safe and has some ability to induce an immune response. If that is successfuland the outbreak has not ended, we will move to a larger Phase 2 clinical trial with theexpectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. Ifefficacious, it will still take additional months to produce enough vaccine to distributewidely ..In addition to this vaccine, NIAID is also supporting scientists and companies to develop othervaccine candidates.5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the Eastin the last 20 years and in 2009 the virus responsible for the flu pandemic too did comefrom China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events?To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China.Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent theunknown from occurring in the first place. What we can do is learn as much as we can aboutemerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics,treatments and vaccines to protect against infection.From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sun, 9 Feb 2020 16:41:33 +0000To: Conrad, Patricia (NIH/NIAID) [ElSubject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel -March 2, 2020 in BostonPlease RSVP no.From: Scala, Steve <Steve.Scala@cowen.com>Se nt: Sunday, February 9, 2020 11:39 AM ------~~ To: Fauci,A nthony (NIH/NIAID) [El- ------- (b)(6) Cc: Nadeau, Phil <Phil.Nadeau@cowen.com>; Miner, Kathy <Kathy.Miner@cowen.com>; Nedelcovych,Michael <Michael. Nedelcovych@cowen.com>Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 inBostonHi Dr. FauciI am a pharmaceutical industry analyst at Cowen and Company, a New York City basedinvestment company that specializes in health care. Each year we host a Health CareConference in Boston in March that attracts 200+ companies and 1000+ investors. During thisyear's conference, we had planned to host a one-hour panel discussion on the evolution of andreforms within the China Health Care System and China Pharmaceutical market. However,given global concerns around Coronavirus, we have decided to focus the panel instead on thevirus and the outlook for emerging treatments. This perspective is critical to health carecompanies and therefore the institutions that invest in them.Our panel will take place during Cowen's 40th Annual Health Care Conference, which will beheld at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel onMonday morning, March 2nd, between 9:05-10:0SAM. Attendees at our conference includeinstitutional investors from insurance companies, mutual funds, pension funds, banks, andother types of funds, mainly in the U.S. and EU.Cowen would provide you an honorarium for your time during the one-hour panel. We proposean honorarium of $1,500, and we reimburse conference-related travel expenses.The discussion will be Q&A only and no presentation on your part is requested .We look forward to hearing from you.Sincerely,Steve ScalaNIH-002042NIH-002043In line with best practices suggested for brokerage firms, Cowen has a policy regarding ourinteraction with subject matter experts such as yourself, and by accepting and participating inthis engagement, you agree to the conditions of this policy, including that you will notknowingly disclose any material non-public and/or confidential information; that your currentemployer permits you to participate in our event; that you are not employed by any of thecompanies anticipated to be discussed; and that your participation will not cause you toknowingly violate any contract (e.g., employment contract or consulting contract), agreement(e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board ofdirectors) that you may have.COWENSteve ScalaPharmaceut ical Industry AnalystEquity ResearchCowen and Company , LLCTwo Internat ional Place, 28th Fl.Boston , MA 02110617-946-3923steve.sca la@cowen.comwww.cowen.comThis message and any attachments are confident ial. If you are not the intended recipient, please notif ythe sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. Allemail sent to or from our system is subject to review and ret ention . Nothing contained in this email shallbe considered an offer or solicitation with respect to the purchase or sale of any securit y in anyjurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of itsaffiliates ("Cowen") represent that any of the information contained herein is accurate, complete or upto date, nor shall Cowen have any responsibility to update any opinions or other information containedherein .From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 2020 16:41:04 +0000Folkers, Greg (NIH/NIAID) [E]Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E]RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2amDefinitely for the Director's pageFrom: Folkers, Greg (NIH/N IAID) [E) (b)(6)Se nt: Sunday, February 9, 2020 9:45 AMSubject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2amIs the Coronavirus the next global pandemic or will the disease be eradicated in a short period oftime? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need toknow about the Coronavirus crisis.Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessarily representmy views nor those of NIAJD, NIB , HHS, or the U.S. government.NIH-002044From:Sent:To:Cc:(b)(6)Sun, 9 Feb 2020 10:53:02 -0500Conrad, Patricia (NIH/NIAID) [ElSubject :Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [ElFwd: CNNI Interview Request: Dr. Anthony Fauci,DoneBegin fo1warded message:From: "Hynds, Joanna (NE)" <Joanna.Hynds@tumer.com>Date: February 9, 2020 at 9:49:2 1 AM ES-T- ---------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6)Cc: "Pfeifer, Hazel" <Hazel.Pfeifer@tumer.com >, "Lovejoy , Hannah (NE)"<Hannah.Lovejoy @tumer.com >, "Fauci, Antho ny (NIH/N IAID) [E]"(b)(6) >Subject: RE: CNNI Interview Request: Dr. Anthony Fauci,Hi Patricia,I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up.DC Number: +l 2025100172 .Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [El (b)(6)>Sent: 09 February 2020 14:42To: Hynds, Joanna (NE) <Joanna.Hynds@turner.com>Cc: Pfeifer, Hazel <Hazel.Pfeife r@turner.com>; Lovejoy, Hannah (NE) ------"-="'""C"-='I <Hannah.Lovejoy@turner.com> ; Fauci, Anthony (NIH/NIAID) [El -------- (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci,We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ET so ifyou can have someone meet him at the entrance lobby to get him upstairs quickly thatwould be helpful.Sent from my iPhoneNIH-002045On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE)<Joanna.Hynds@turne r.com>wrote :Hi Pat ricia,That would be perfect. I am so sorry on the miscommun icat ion on my part.We really appreciate you accommodating us at this short notice .Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>Sent: 09 February 2020 14:35To: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Cc: Pfeifer, Hazel <Hazel.Pfeifer@t urner .com>; Lovejoy, Hannah (NE)<Hannah.Lovejoy@turner .com>; Fauci, Anthony (NIH/NIAID) [E](b)( >Subject : Re: CNNI Interview Request: Dr. Anthony Fauci,Dr DrFauci can be there for a 1030 am hitWe need to know ASAP if this is firm and what the exact hit timeSent from my iPhoneOn Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE)<Joanna.Hynds@turne r.com>wrot e:Just wanted to let you know the Flash Studio will be DC G StudioCAM23Our Bureau Address is820 First ST NE20002 WashingtonPlease contact the bureau at +1-202-898-7911NIH-002046Please arrive at 10.40, you will be on around 11 - 1 will updatewith exact hit time as soon as I have it.Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [E)(b)(6)>Sent: 09 February 2020 13:33To: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Cc: Pfeifer, Hazel <Hazel.Pfeife r@turner .com>; Lovejoy, Hannah(NE) <Hannah.Lovejoy@turne r.com>; Fauci, Anthony(NIH/NIAID) [E] (b)(6)Subject: Re: CNNI Interview Request: Dr. Anthony Fauci,Adding Dr Fauci hereHe can come to the WDC CNN studio. Please send us the exactlive hit time as well as the stud io address and on-site contactname, number and cell numbe r ASAP. Dr Fauci cell is (b)(- and you have mine.Thank you.Sent from my iPhoneOn Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE)<Joanna.Hynds@turner .com>wrote:Dear Pat ricia,Just following up from our phone conversation,unfortunately I won't be able to facilitate aStudioGo truck for this interview .We are still really keen to get Dr Fauci on the show- will he be able to come to the bureau?I will be able to book him a car if he needs.Let me know what suits,NIH-002047Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [E](b)(6)>Sent : 09 February 2020 13:00To:H ynd~Joanna(NE)<Joanna.Hynds@turner .com>Subject : Re: CNNI Interview Request: Dr. AnthonyFauci,For the trick- the location is northwest WashingtonDC. Near American university.Sent from my iPhoneOn Feb 9, 2020, at 7:51 AM, Conrad,Patricia (NIH/NIA ID) [E)--------- (b)( >wrote:Please call me ASAP at -----(b)(6) for this request.Sent from my iPhoneBegin forwarded message:From: "Fauci, Anthony(NIH/NIAID) [El"(b)(6)Date : February 9, 2020at 7:08:54 AM ESTTo: "Conrad, Patricia(NIH/NIAID) [El"(b)(6) • Subject: Fwd: CNNIInterview Request: Dr.Anthony Fauci,NIH-002048Sent from my iPhoneBegin forwardedmessage:From:"Hynds,Joanna(NE)"<Joanna.Hynds@turner .com>Date :February9, 2020 at6:06:15AM ESTTo: "Fauci,Anthony(NIH/NIAiD) [E]"(b)(6) -■ Cc:"Tejera,Isabel(Intern)"<isabel.Tejera@turner.com >,"Lovejoy,Hannah(NE)"<Hannah.Lovejoy@turner .com>Subject:CNNIInterviewRequest:Dr.AnthonyFauci,NIH-002049NIH-002050Dear DrFauci,I hope youare well! Iamreachingout fromCNNlnternational toenquire ifyou areavailabletoday tojo in us onConnectthe Worldat llaETto discussthecoronavirus.Might thisbe apossibility? It wouldbe greatto arrangethis.Backgroundon CNN• CNNInternationalreachesNIH-002051morethan250miIiionhouseholdsworIdwideincludingintheusviaDIRECTV.• CNNInternationalistheNIH-002052numberoneinternationalTVnewschanneaccordingtoallmajormediaSUrveysacrossEuropetheMiddNIH-002053leEastandAfrica,theAsiaPacificregionandLatinAmerica• InSeptember2019~NN.comhad162miIiionNIH-002054uniquereadersgloballypermonthand114miIiionmobilereadersamonthleadingtheBBC,Yaho0andBest,Jo annaHyndsNewYorkTimesPlanningDeskCNNInternational+ 44 207693 1640( office)(b)(6)~ (cell)joanna.hynds@turner.com<imageOO1.png>lnformation in thisemailincludinganyattachments maybepriv ilegedorconfidential and isintendedexclusive lyfor theaddresseeNIH-002055NIH-002056. Theviewsexpressedmay notbe officialpolicy, butthepersonalviews oftheoriginator.If youhavereceivedthis emailin error ,pleasenotify thesender byreturn emailanddelete itfrom yoursystem .Youshould notreproducedistribute,store,retransmit, use ordiscloseitscontentsto anyone .Pleasenote wereservethe righttomonitorall e-mailcommunicationthroughourinternalNIH-002057andexternalnetworks.Turnerand theTurnermarks aretrademarks ofTurnerBroadcasting SystemInc andare usedunderlicence.TurnerBroadcasting SystemEuropeLimited(CompanyNo.1927955),TurnerEntertainmentNetwo rkslnternat ionalLimited(CompanyNo.2803512),TurnerBroadcasting SystemHoldings(Europe)Limited(CompanyNumber2802926)and CableNewslnternat ionalNIH-002058Limited(CompanyNo.5001368)areincorporatedinEnglandand Walesand sharethe sameregisteredoffice atTurnerHouse, 16GreatMar lboroughStreet,LondonWlF 7HS.Informat ion in this emai l including anyattachments may be privileged or conf identia l andis intended exclusively for the addressee. 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Turner and theTurner marks are trade marks of TurnerBroadcasting System Inc and are used underlicence.Turner Broadcasting System Europe Limited(Company No. 1927955), Turne r Enterta inmentNetworks Internationa l Limited (Company No.2803512), Turner Broadcasting System Holdings(Europe) Limited (Company Number 2802926) andCable News International Limited (Company No.5001368) are incorporated in England and Walesand share the same registered off ice at TurnerNIH-002059House, 16 Great Marlborough Street, London WlF7HS.Information in this email including any attachments may beprivileged or confidential and is intended exclusively for theaddressee. The views expressed may not be official policy, butthe personal views of the originator. If you have received thisemail in error, please notify the sender by return e-mail anddelete it from your system. You should not reproduce,distribute, store, retransmit, use or disclose its contents toanyone. Please note we reserve the right to monitor all e-mailcommunication through our internal and external networks.Turner and the Turner marks are trade marks of TurnerBroadcasting System Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No.1927955), Turner Entertainment Networks International Limited(Company No. 2803512), Turner Broadcasting System Holdings(Europe) Limited (Company Number 2802926) and Cable NewsInternational Limited (Company No. 5001368) are incorporatedin England and Wales and share the same registered office atTurner House, 16 Great Marlborough Street, London WlF 7HS.Information in this email including any attachments may be privileged orconfidential and is intended exclusively for the addressee. The viewsexpressed may not be official policy, but the personal views of the originator.If you have received this email in error, please notify the sender by return emailand delete it from your system. You should not reproduce, distribute,store, retransmit, use or disclose its contents to anyone. Please note wereserve the right to monitor all e-mail communication through our internaland external networks. Turner and the Turner marks are trade marks ofTurner Broadcasting System Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No. 1927955), TurnerEntertainment Networks International Limited (Company No. 2803512),Turner Broadcasting System Holdings (Europe) Limited (Company Number2802926) and Cable News International Limited (Company No. 5001368) areincorporated in England and Wales and share the same registered office atTurner House, 16 Great Marlborough Street, London WlF 7HS.Information in this email including any attachments may be privileged orconfidential and is intended exclusively for the addressee. The views expressed maynot be official policy, but the personal views of the originator. If you have receivedthis email in error, please notify the sender by return e-mail and delete it from yoursystem. You should not reproduce, distribute , store, retransmit, use or disclose itscontents to anyone. Please note we reserve the right to monitor all e-mailNIH-002060communication through our internal and external networks. Turner and the Turnermarks are trade marks of Turner Broadca sting System Inc and are used underlicence.Turner Broadcasting System Europe Limited (Company No. 1927955), TurnerEntertainment Networks International Limited (Company No. 2803512), TurnerBroadca sting System Holding s (Europe) Limited (Company Number 2802926) andCable News International Limited (Company No. 5001368) are incorporated inEngland and Wales and share the same registered office at Turner House, 16 GreatMarlborough Street, London W 1 F 7HS.From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 2020 13:05:06 +0000To: Kaplan, Edward HCc: Redfield, Robert R. (CDC/OD);Cetron, Marty(CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD)Subject: RE: Coronavirus containment modelingAttachment s: hems_ Wuhan_Feb7 _2020_1n_Press.pdfEd:Many thanks for sendjng the manuscript . I hope that all is well with you.Best regards,Tony-----Original Message------------~~ From: Kaplan , Edward H (b) (6)>Sent: Saturday , February 8, 2020 I 0: 13- -PM-- --~~ To: Fauci , Anthony (NTH/NlAID) [E] (b)(6) >Subject: Coronavirus containment modeLingDear Dr. Fauci,It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI.The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation andquarantine might interest you. The news is mostly good - isolation and quarantine can ge1 the transmission ratebelow epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas foralleviating congestion in the hospital. I hope that you find it helpful.Best, Ed KaplanEdward H. Kaplan, Ph.D.William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor ofEngineering Yale School of Management Box 208200 New Haven, Conne cticut 06520-8 200Phone: (b)(6)e-mai l: _______ C_b)_C_6 )http://faculty.som.yale.edu/EdKaplan/NIH-002061From:Sent :To:Subject:Fauci, Anthony (NIH/NIAID) [E)Sun, 9 Feb 2020 12:40:23 +0000Conrad, Patricia (NIH/NIAID) [ElRE: CNNI Interview Request: Dr. Anthony Fauci,I will do this and if they can bring a truck to the house like they did last time, it was great. Letus discuss.From: Hynds, Joanna (NE) <Joanna.Hynds@turner.com>Sent: Sunday, February 9, 2020 6:06 AM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)Cc: Tejera, Isabel (Intern) <isabel.Tejera@turner.com>; Lovejoy, Hannah (NE)<Hannah.Lovejoy@turner.com>Subject: CNNI Interview Request: Dr. Anthony Fauci,Dear Dr Fauci,I hope you are well! I am reaching out from CNN International to enquire if you are available today tojoin us on Connect the World at llaET to discuss the coronav irus.Migh t this be a possibility? It would be great to arrange this.Background on CNN• CNN International reaches more than 250 million households worldwide including in the US viaDIRECTV.• CNN International is the number one internat ional TV news channel according to all majormedia surveys across Europe, the Middle East and Africa, the Asia Pacific region and LatinAmerica.• In September 2019 CNN.com had 162 million unique readers globally per month and 114 millionmobile readers a month, leading the BBC, Yahoo and New York Times.Best,Joanna HyndsPlanning DeskCNN International+ 44 207 693 1640 (office)+ (b)(6) {cell)joanna.hynds@turner .com■ go thereNIH-002062NIH-002063Information in this email including any attachments may be privileged or confidential and is intendedexclusively for the addressee. The views expressed may not be official policy, but the personal views ofthe originator. If you have received this email in error, please notify the sender by return e-mail anddelete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose itscontents to anyone. Please note we reserve the right to monitor all e-mail communication through ourinternal and external networks. Turner and the Turner marks are trade marks of Turner BroadcastingSystem Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment NetworksInternationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited(Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) areincorpo rated in England and Wales and share the same registered office at Turner House, 16 GreatMarlborough Street, London WlF 7HS.From:Sent :To:(b)(6)Sun, 9 Feb 2020 07:08: 49 -0500Conrad, Patricia (NIH/NIAID) [E)Subject: Fwd: CNNI Interview Request: Or. Anthony Fauci,Sent from my iPhoneBegin forwarded message:From: "Hynds, Joanna (NE)" <Joanna.Hynds@tumer.com>Dat e: February 9, 2020 at 6:06:15 AM ES-T-- ---~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH >Cc: "Tejera, Isabel (Intern)" <isabel.Tejera@turner.com >, "Lovejoy , Hannah (NE)"<Hannah.Lovejoy @turner.com>Subject: CNNI Interview Request: Dr. Anthony Fauci,Dear Dr Fauci,I hope you are well ! I am reaching out from CNN International to enqui re if you areavailable today to join us on Connect the World at ll aET to discuss the coronavirus.Might this be a possibility? It would be great to arrange this.Background on CNNBest,• CNN International reaches more than 250 million households wor ldwide includingin the US via DIRECTV.• CNN International is the number one international TV news channel according toall major media surveys across Europe, the Middle East and Afr ica, the Asia Pacificregion and Latin America .• In September 2019 CNN.com had 162 million unique readers globally per monthand 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New YorkTimes.Joanna HyndsPlanning DeskCNN International+ 44 207 693 1640 (office)+ (b)(6) ( cell)NIH-002064NIH-002065joan na. hynds@turner.com mmgo t hereInformation in this email including any attachments may be privileged orconfidential and is intended exclusively for the addressee. The views expressed maynot be official policy , but the personal views of the originator. If you have receivedthis email in en-or, please notify the sender by return e-mail and delete it from yoursystem. You should not reproduce, distribute, store, retransmit, use or disclose itscontents to anyone. Please note we reserve the right to monitor all e-mailcommunication through our internal and external networks. Turner and the Turnermarks are trade marks of Tmner Broadcasting System Inc and are used underlicence.Turner Broadcasting System Europe Limited (Company No. 1927955), TurnerEntertainment Networks International Limited (Company No. 2803512) , TmnerBroadcasting System Holdings (Europe) Limited (Company Number 2802926) andCable News International Limited (Company No. 5001368) are incorporated inEngland and Wales and share the same registered office at Turner House, 16 GreatMarlborough Street, London WlF 7HS.From:Sent:To:Subject :Janee:Fauci, Anthony (NIH/NIAID) [E)Sun, 9 Feb 2020 03:33:50 +0000Janet TobiasRE: Background questionNothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although therehave been specu lation that because there is about 80-90% homology between nCo V and SARS that there may besome use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera frompatients with nCoV and checked if it neutralized SARS and vice versa.Best,Tony-----Original Message-----From: Janet Tobias <janet@ikanamed ia.com>Sent: Sanrrday,F ebruary 8, 2020 6:27 -P-M- -----=,-,--:= To: Fauci, Anthony (NIH/NIAID) [E] ______ C>b<_·Subject: Background questionDear Tony: I have a background question as I am wading through reading as much as possible on the 2019coronavirus. Do we know if the antibodies 1hat can neutralize SARS are also effective against the 2019 corona virus?] may be complete ly off track, but just liying to think through some things l am reading.JanetSent from my iPhoneNIH-002066From:Sent :To:Subject:Fauci, Anthony (NIH/NIAID) [E)Sun, 9 Feb 2020 03:28:39 +0000Lenardo, Michael (NIH/NIAID) [E]RE: Hope you're doing well.Thanks, Mike. Am hanging in there.From: Lenardo, Michael (NIH/NIAID) [E]- -------- (b) ~ > Se nt: Saturday, February 8, 2020 5:18 PMTo: Fauci, Anthony (NIH/NIAID) [E] -------=- (b)c-(c= >Subject: Hope you're doing well.Hi Tony,Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sureyou're busy with the coronav irus crisis.You continue to be my inspiration!Best wishes, MikeMichael Lenardo M.D.NIH Distinguished InvestigatorChief, Molecular Development of the Immune System SectionLaboratory of Immune System Biology,Director, Clinical Genomics Program,Nationa l Institute of Allergy and Infectious DiseasesNationa l Institutes of HealthBuilding 10, Room 11D1410 Center Drive, MSC 1892Bethesda, MD 20892-1892 USATel: (b)(6) (O); (b)(6)(M)FAX: 301-402-8530Email: (b)(6) ------ASSISTANT: Gloria RodelaTel: (b)(6)Email (b)(6)NIH-002067From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Sat, 8 Feb 2020 20:54:52 +0000(b)(6)Subject:Attachments :FW: Invitenejmoa2001316.pdfHere it is. As discussed, let us re-read and convene sometime tomorrow tooutline our approach.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone Cb()6 )FAX : (301 496-4409E-mail : Cb()6 )The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Baden, Lindsey, M.D.<lbaden@nejm.org>Sent: Saturday, February 8, 2020 12:51 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( >Subject: InviteTony,As I am sure you are aware we recently web released the attached paper providing some initialestimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out ina print issue and we would like an editorial to go with it. Might you be w illing/interested in authoringsuch a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as youprovide it to us we will web release it and then link it with the attached article in an upcoming printissue. Are you interested?Please confirm no potential COis.Thank you for considering,LindseyLindsey R. Baden, MDDeputy EditorNew England Journal of MedicineNIH-002068NIH-002069This email message is a private communication. The information transmitted, including attachments , isintended only for the person or entity to which it is addressed and may contain confidential, privileged,and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, ortaking of any action in reliance upon, this information by persons or entities other than the intendedrecipient is unauthorized by the sender and is prohibited. If you have received this message in error,please contact the sender immediately by return email and delete the original message from allcomputer systems. Thank you.From:Sent :To:Cc:Subject:Sae:Fauci, Anthony (NIH/NIAIO) [E)Sat, 8 Feb 2020 17:44:45 +0000Robinson, Sae;Conrad, Patricia (NIH/NIAID) [Elnaugenstein@wtop.comRE: request for info from WTOP's Neal AugensteinI assume that this is taken care of with the interview that I just gave fo r WTOP todayThanks,TonyFrom: Robinson, Sae <srobinson@wtop.com>Sent : Saturday, February 8, 2020 7:57 AM -------~= To: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6)Subject: Re: request for info from WTOP's Neal AugensteinWe will call at 11:20 am. Thank you both!On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El- -------- (b)(6)> wrote:Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please callhim at (b)(6) back up cell at (b)(6)What is the exact hit time?Sent from my iPhoneOn Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E]-------- (b)( > wrote:Sae:Patty wi ll get back to you today.Best,TonyFrom: Robinson, Sae <srobinson@wtop.com >Sent : Saturday, February 8, 2020 7:06 AM -------~~ To: Conrad, Patricia (NIH/NIAID) [EI_ _______ C>b_C_,; Fauci,NIH-002070Anthony (NIH/NIAID) [E] -------- (b)(6)Subject: Re: request for info from WTOP's Neal AugensteinGood morning.I'd like to follow up on yesterday's inquiry from our repo rter Neal.If Dr. Fauci is available to address the concerns of this cruise ship in Japanwith Corona virus (re: air circulation system) today, we'd love him to havehim on.Unfortunately, the first available interview time is after 11 a.m.If it works, please let me know. This time, we'd like to record an interview tobe used for air so we have some flexibility.Thank you !Sae RobinsonWTOP News202-895-5060On Feb 7, 2020, at 12:59, Augenstein, Neal<naugenstein@wtop .com> wroteBegin forwarded message:From: "Conrad, Patricia (NIH/NIAID) [E]"(b)( >Date : February 7, 2020 at 12:17:40 PM ESTTo: "Augenstein, Neal" <naugenstein@wtop .com>Subject: RE: request for info from WTOP's NealAugensteinDr Fauci asked that I respond - he is inback to back meeting today up untilabout 7 pm. If you want to speak withhim tomorrow-we might be able tomake that workPatricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNIH-002071National Institute of Allergy and InfectiousDiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301 -496 -4409 faxDisclaimer:The information in this e-mail and any of its attachments isconfidential and may contain sensitive information. It should notbe used by anyone who is not the original intended recipient. Ifyou have received this e-mail in error please inform the senderand delete it from your mailbox or any other storage devices.National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liabi lity for any statement made that aresender's own and not expressly made on behalf of the NIAID byone of its representatives.From: Augenstein, Neal<naugenstein@wtop .com>Sent: Friday, February 7, 2020 8:29 AMTo: Fauci, Anthony (NIH/NIAID) [E](b) (6)>Subject: request for info from WTOP's NealAugensteinHi, Dr. Fauci. Hope you're wellSpokew ith some passengersa board the DiamondPrincess cruise ship in Japan, where the number ofcoronavirus cases onboard are jumping. Can we doa brief interview re: thoughts on quarantining onboard ship (with, I would assume a closedcirculating air system) versus evacuating them?I'm available at your earliest convenience. Or, ifyou'd like to just email some thoughts, that'd begreat. Thanks and best.NIH-002072Neal AugensteinReporter103.SFM and wtop.comWashington, DC(b)(6) cell202-895-5060 newsroomnaugenstein@wtop.comTwitter: @AugensteinWTOPSkype: WTOPNealAugensteinNIH-002073From:Sent:To:Cc:Fauci, Anthony (NIH/NIAIO) [E)Sat, 8 Feb 2020 17:30:45 +0000Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [ElNIAID ODAMSubject :desktop?RE: David ·• how do we put a link to the Coronavirus public folder on ASF'Monday is fine .From: Awwad, David (NIH/NIAID) [C) --------- (b)( >Sent: Saturday, February 8, 2020 12:11 PMTo: Folkers, Greg (NIH/NIAID) [E]--------=- (b")("=6")>Cc: NIAID OD AM <NIAIDODAM@niaid .nih.gov>Subject : Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop?I will add Monday, unless you want me to connect now.Sent from my iPhoneOn Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [Elwrote:<image0Ol. jpg>(b)(6)Disclaimer: Any third-part y material iu this email has been shared for internal use under fairuse provisions of U.S. copyright law, without further verification of its accuracy/veracity. Ltdoes not necessa rily repr esent my views nor those of NIA ID, NIH, HHS, or the U.S.goverumeut.NIH-002074From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sat, 8 Feb 2020 17:29:51 +0000To: Conrad, Patricia (NIH/NIAID) [E)Subject: FW: Fox and Friends video -- US confirms first American coronavirus death/ ASFauci http;/ /bit.ly /2tltgneFyi. It came out well.From: Folkers, Greg {NIH/N IAID) [E) (b)(6)Se nt: Saturday, February 8, 2020 11:34 AMSubject: Fox and Friends video -- US confirms first American coronav irus death/ AS Faucihttp://bit .ly/2tltgneDisclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisionsof U.S. copyrig ht law, without further verification of its accuracy/veracity . It docs not necessarily repre sentmy views nor those of NlAlD, NIH, HHS, or the U.S. government.NIH-002075From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAID) [E)Sat, 8 Feb 2020 17 :24 :25 +0000Conrad, Patricia (NIH/NIAID) [E)Barasch, Kimberly (NIH/NIAID) [C)RE: CNN Interview Request: Dr. Anthony FauciI believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We mayalso be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that this istaped. I leave this up to you and so please get back to them and work it out if you can. JimSciutto CbH6)), Thanks.From: Griffin, Janelle <Janelle.Griffin@turner.com>Sent : Saturday, February 8, 2020 11:33 AM -------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)Subject: CNN Interview Request: Dr. Anthony FauciImportance: HighGood mornin g Dr. Fauci ,I hop e this email finds you doing well.I'm reaching ou t on behalf of Newsroom w/Popp y Harlow & Jim Sciutto hop ing you can join for aninterview.Are you available to join CNN this Monday February l 0th in the 1 Oa et hour?This would be live for about 5-7 minutes to discuss developments regarding the coronavirus.Please feel free to contact me via email or at ------Cb)( 6) to let me know.Thanks for your time- I look forward to hearing from you soon.Janelle Griffin-ButtsEditorial Producer, CNNEmail: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN NNIH-002076From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sat, 8 Feb 2020 03:23:51 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ETI am OK with their coming to the house without a truck. I will call you in the AM.From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)>Sent: Friday, February 7, 2020 7:42 PMTo: Fauci, Anthony (NIH/NIAID) [E]--------=- (b'")("=6' )>Subject: Fwd: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ETAm at din ner. Will call u laterSent from my iPhoneBegin forwarded message:From: "Zuccaro, Alexandra" <Alexandra.Zuccaro@FOXNEWS.COM>Date : February 7, 2020 at 7:16:21 PM EST -------~= To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ETThey'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too!From: Conrad, Patricia (NIH/NIAID) [E) ----------- (b)(6) Sent: Friday, February 7, 2020 6:51 PMTo: Zuccaro, Alexandra <Alexand ra.Zuccaro@FOXNEWS.COM>Subject: (EXTERNAL] Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30amETWill they set up outside his house or is this the trick that he goes into it for the interview?Sent from my iPhoneOn Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra<Alexand ra.Zuccaro@foxnews.com > wrote:Hi Everyone,NIH-002078Babu Aryankalayil is set to arrive at (b)(6)around 7:30am/est tomorrow for our interview with Dr. Anthony Fauci. Babu,please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFBand Pl Numbers are below. Please let us know if you have any questions, andplease also let us know what REM this will be on."Fox & Friends"DATE: Saturday, February 8thCREW ARRIVAL TIME: 7:30am ETADDRESS: (b)(6) -------------LIVE TALK BACK: 8:35am ET - 8:40am ET with Pete Hegseth, Emily Compagno,& Jason ChaffetzSatellite Window : 0700 -0800GUEST: Dr. Anthony FauciTOPIC: CORONAVIRUS CRUISE SHIP LATESTGUEST CONTACT: Dr. Anthony Fauci, (b)(6) / Media contact PatriciaConrad cell : (b)(6)cell :-_:..!:====:::!..: (b ~ )- (~6)CREW CONTACT: Babu Aryankalayi l, -----(b)(6)/ (b)(6)F&F NYC CONTACTS:Technical Director: Todd Boone: Phone -----(-b)(6) email: todd.boone@foxnews.comF&F Control Room Contact: Tami Radabaugh, (b)(6) email:Tami .Radabaugh@FOXNEWS.COMPl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4)IFS: 800-369-6719ACQ and REM Coordinator : 212-301-3200NY Transmission : 212-301-3100NY Sat Desk {Bookings) 212-301-3400A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYCGreenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COMThanks,Alexandra ZuccaroNIH-002079"Fox & Friends"Fox News Channel1211 Avenue of the Americas, 2nd FloorNew York, NY 10036Cell : (b)(6)Alexandra .Zuccaro@FOXNEWS.COMThis message and its attachments may contain legally privileged orconfidential information. It is intended solely for the named addressee .If you are not the addressee indicated in this message ( or responsible fordelivery of the message to the addressee) , you may not copy or deliverthis message or its attachments to anyone . Rather, you shouldpermanently delete this message and its attachments and kindly notifythe sender by reply e-mail. Any content of this message and itsattachments that does not relate to the official business of Fox News orFox Business must not be taken to have been sent or endorsed by eitherof them. No representation is made that this email or its attachments arewithout defect.NIH-002080From:Sent :To:Cc:Fauci, Anthony (NIH/NIAID) [E)Fri, 7 Feb 2020 20:20:58 +0000Mellors, John WSubject:Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [ClRe: Important Brief ConversationAttachments : image0Ol.gifI know. Glad we could work it outOn Feb 7, 2020, at 11: 48 AM, Mellors, John W ------ (b)(6) wrote:Dear Tony,Approva l received from DHHS. The shipment of remdesivir to China is on it's way.No need to connect.Thanks,JohnFrom: Fauci, Anthony (NIH/N IAID) [E) (b)(6)>Sent: Thursday, February 6, 2020 7:04:53 PMTo: Mellors, John W -~----(b)- ( ->- -----~~ Cc: Conrad, Patricia (NIH/N IAID) [E] (b)( ; Barasch, Kimberly{NIH/NIAID) [C] (b)(6)Subject: RE: Important Brief ConversationJohn:Please give me office a call tomorrow and they will set up a time to connect us.Best,TonyFrom: Mellors, John W (b)(6)Sent : Thursday, February 6, 2020 5:38 PM ---------------=~ To: Fauci, Anthony (NIH/N IAID) [El (b)(6)·_...:._ _ :....:.,..:.~-------------- Cc: Mellors, John W (b)(6)>Subject: Importan t Brief ConversationDear To ny , CliffCould we speak briefly about an important interna tio nal coronavirus trial that is injeopardy?My mob ile phone number is -----(b)(6)JohnNIH-002081John W. Mellors, M.D.Chief, Division of Infectious DiseasesDistinguished Professor and Endowed Chair for Elimination of HIV and AIDSUniversity of Pittsburgh Schoo l of Medic ineScaife Hall , Suite 8183550 Terrace StreetPittsburgh, PA 15261Tel : (b)(6)Fax: 412 383-7982E-mail: (b)(6)Visit our Division website: http://www.dept-med.pitt.edu/lD/Read the "ID Pitt Stop" blog: https://idpittstop.wordpress.comLike us<image00 1. gif>NIH-002082From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 15:37:53 +0000(b)(6)Subject: RE: NIH posit ion on travel to Singapore???Go to CDC we bsite. There are no t rave l alerts fo r Singapore and so f or now it isOK to trave l t here.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: (b)(6) ----------------- Sent : Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E]-- -------------=(b~)(6)> Subject: Fwd: NIH position on travel to Singapore???jim lynch is asking for sources of info for travel advice re: coronavirus . ___ C_b><6) is planning to go toSingapore . any suggestions?---------- Forwarded message ---------From: James L (b)(6)>Date : Thu, Feb 6, 2020 at 8:16 AMSubject: NIH position on travel to Singapore???To: 00~Hi (b)(6)------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week .What is the best source of up-to -date information and travel recommendations related to thecoronavirus?ThanksNIH-002083Jim(b)(6)NIH-002084From:Sent:To:Subject :Let us discus.Fauci, Anthony (NIH/NIAID) [E)Fri, 7 Feb 2020 10:46:54 +0000NIAIDODAMFW: Royal Society of Medicine london-----Original Message -----From: Ian Hosein _________ ("b,a)"(=S "'"Sent: Friday, February 7, 2020 5:20 A-M- ----~~= To: Fauci, Anthony (NIH/NIAID) [E].___ ____ C>b<.. ..Subject: Royal Society of Medicine londonHello Dr Fauci,By way of introduction , 1 was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since thenas a medi cal microbio logist and hospital epidemio logist.J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about youravailabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November24th coming?The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The programis still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I canapply to cover your trip but will need to do so soon.Jt was both exciting and inspirational being a senior staff fellow at the Nll-1 - my background is international;--,------------,---,-,,-----,-....,...,.,...-----,,--,-,---(b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH forthe US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought thespirit of that institution to other nations.With kind regards ,lanlan K Hosein MD FCAP FRCPath MBARoyal Society of MedicineLondonMobi le--- (~b)~(6=)Sent from my iPadNIH-002085From:Sent :To:Subject:Attachment s:Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:56:15 +0000Conrad, Patricia (NIH/NIAID) [ElFW: Comment on NEJM details of "asymptomat ic" contact in Germanynejmc2001468_appendix.pdfPlease set up a call. Happy to do over the weekend or Friday evening.From: Ian Ingram <iingram@medpagetoday.com>Sent : Thursday, February 6, 2020 1:34 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)( >Subject: Comment on NEJM details of "asymptomatic " contact in GermanyHi Or. Fauci,I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPageToday, but I wanted to see if you could were available to offer your quick reaction to the Supplement aryIndex publ ished today (attached) in the New England Journal of Medicine regarding the widely reportedasymptomati c contact in Germany.Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies assymptomatic or not . I imagine this will be disputed.Best regards,- IanIan IngramDeputy Managing Edi torMedPage Today LLC(b)(6)iingram@medpagetoday.commedpagetoday. comNIH-002086From:Sent :To:Cc:Subject :Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:53:47 +0000Conrad, Patricia (NIH/NIAID) [E)Barasch, Kimberly (NIH/NIAID) [C)FW: BuzzFeed News; 2019-nCoV vaccine development questionsPlease set up a call with this person. Happy to do over the weekend.From: Dan Vergano <dan.vergano@buzzfeed .com>Sent : Wednesday, February 5, 2020 3:18 PM ------- ~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6)Subject : BuzzFeed News: 2019-nCoV vaccine development questionsDr. Fauci,As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have anyperspective (or might recommend someone to commen t) for a novel coronavirus story we are writingfor this weekend, regarding vaccine efforts .In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDChas described the virus as not mutating as much as influenza -- does that suggest a vaccine wouldprovide more than seasonal protection?In the long te rm, we had a few other questions. Is this something you could see added to the MMRprotoco l for the general public, or only in regions where there are local outbreaks (is there an analogy toSARS or MERS vaccines in this contemplated use)? Is the re any aspect of a race against time in vaccinedevelopment if this coronavirus is seasonal like influenz a?We are basically trying to understand where a vaccine fits into the future response to this new virus. weasked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot.Apologies for all the quest ions, if you had any perspective, we'd be gratefulDan VerganoBuzzFeed News(b)(6)cc: Kathy StoverDan Verg ano I Science Desk (DC) IBuzzFeed News-----(b)(6)1630 Connecticut Ave. 7th Floor, Washington DC 20009Send secure tips -- cont act .buzzfeed.comNIH-002089From:Sent :To:Subject :Very interesting! !Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:45:34 +0000Folkers, Greg (NIH/NIAID) [E]RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan casesFrom: Folkers, Greg (NIH/NIAID) [E] (b)(6)>Sent: Thursday, February 6, 2020 2:22 PMTo: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c=Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El(b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea":'---:----:-~===:::.;..--~~(NIH/NIAID) (E] (b)(6)]; Marston , Hilary (NIH/ NIAID) (El (b)(6)Subject : ASF / please see table from 1-29-20 19 NEJM paper on Wuhan casesPlease see next to last line, wh ich gives% of transmissions with "no exposure to either marketor person with respiratory symptoms"(b) (5)N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print]Early Transmission Dynamics in Wuhan, China,of Novel Coronavirus-lnfected Pneumonia.Li Q1, Guan x1, Wu P1, Wang x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1,Xiang N1, Wu Y1, Li C1, Chen Q1, Li D1, Liu r 1, Zhao J1, Li M1, Tu W1, Chen c1, Jin L1, Yang R1, Wang Q1,Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 81, Ma z1, Zhang Y1,Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowling BJ1, Yang B1, Leung GM1, Feng z1.DOl:10.1056/NEJMoa2001316NIH-002090NIH-002091e(r 11:&e)-y_ - no./cow no. (")els yr1S yr'1S-64 r65 ~'e , - no./tot no. (%)posure 15 OI)'- no./tot I no. (")We1 ma et posurHu II n Seafood Wholewle M ,kcOther muk b-ul not Hu1n•n S 1foodH C n:c-1ConHe,I c~rl' wor c-r - no /tot1I no , ('(,)lklore January l January l 1 an11 r,r 11(N• 471 [ - u•1S6 (26--32) 60(21 9)0/47 0/24312/◄ 7 (26) 39[24 (16)24/47 (5 ) 06/24 (0)11/47 (23) 03/:J.48 (42)31/47 (66) 147/24 (59)J0/O (641 12/196116)26/47 (5S) 19/196 (10)"''' (9)U/196 (7)Hi/47(30 30/196 (15)12f47 (26) 141(196 {72)0/1.7Rc,duc~ denom1na ors 1ndic le m1ssin da t P ccMu es m1r no to 100 b« use o round nJanLE&l'Yl2 -:I u 22(N• llO)6 ( S.-89)OJlJOH/130(25)49/lJO(lSJ&/ 30 (37)62/ 30 (48)s (6)5/81 (6)0/8121/83 (25)59/81 (73)a,m (1)Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily representmy views nor those ofNIAID , NIH , HHS, or the U.S. government.From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:38:45 +0000Conrad, Patricia (NIH/NIAID) [E)Barasch, Kimberly (NIH/NIAID) [C)FW: LatestPlease set up a call with David for the weekend.From: davidwillman (b)(6)Sent : Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)-_ -_-_-_-_-_~_ ~ CbH_6)Subject: LatestHi Tony,I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like toconfer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'llalso call Kim Barasch, per your recent guidance.I'm researching an article that will chiefly explore the status of the Defense Department's advanceddevelopment and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re thethree HHS/BARDA facilities.Best, DavidDavid WillmanWashington Post202-334-7081-desk----C-b)-( 6) -mobile 301-656-3401 --alternate deskdavid.willman@washpost .com(b)(6)NIH-002092From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:11: 47 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: FW: Reporter working on coronavirus vaccine storyLet us discuss. Maybe over the weekendFrom: Morris , Amanda <Amanda.Morris@gannett.com>Se nt: Thursday, February 6, 2020 4:11 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b')"("=6')Subject: Reporter working on coronavirus vaccine storyHi Anthony,I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the ArizonaRepublic, part of the USA Today network. I'm reaching out because I'm currently working on a storyabout how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to developstrategies to make a vaccine against the new coronav irus as well as a general platform they can use inthe case of future new coronavirus strain outbreaks in humans.I know globally there are many researchers trying to develop a vaccine for this new coronavirus, andthat the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'mwondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing,and what the broader challenges are for developing a vaccine? I'd like to have broader context aboutvaccines for our readers.Please let me know as soon as possible. You can call or text me at -----(b)(6) Thank you!All my best,Amanda Mo r risBioscience Reporter for The Arizona RepublicWork phone: 602-444-8739After hours and weekends, you can call or text my cell: __ (_b)_(6_J.Email : amor ris@gannett .comNIH-002095From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:04:53 +0000Mellors, John WCc:Subject :Conrad, Patricia (NIH/NIAID) [E);Barasch,K imberly (NIH/NIAID) [CJRE: Important Brief ConversationJohn:Please give me office a call tomorrow and they will set up a time to connect us.Best,TonyFrom: Mellors, John W (b) (6)Sent: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,A nthony (NIH./:.N. _IA_ID..):...[.E:._~).; ~------------ (b_)(6)Cc: Mellors, John W (b)(6)Subject : Important Brief ConversationDear Tony, CliffCould we speak briefly about an importan t international coronavirus trial that is in jeopar dy?My mobile phone number is -----(b)(6)JohnJohn W. Mellors, M.D.Chief, Division of Infectious DiseasesDistinguished Professor and Endowed Chair for Elimination of HIV and AIDSUniver sity of Pittsburgh School of MedicineScaife Hall, Suite 8183550 Terrace StreetPittsburgh , PA 15261Tel: CbH6)Fax: 412 383-7982E-mail Cb()6 )lVisit our Division website: http ://www.dept-me d.pitt.edu/ lD/Read the "ID Pitt Stop" blog: https://idpittstop.wor dpress .comLike us (INIH-002096From:Sent :To:Subject:Howard:Fauci, Anthony (NIH/NIAI0) [E)Fri, 7 Feb 2020 03:01:07 +0000Howard BauchnerRE: Subtitled Coronavirus VideoThanks for the feedback.Best,TonyFrom: Howard Bauchner <Howard.Bauchner@jamanetwork.org>Sent: Thursday, February 6, 2020 6:39 PM ------ --.~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J>Subject: FW: Subtitled Coronavirus VideoTonyFirst live stream/podcast now with Chinese interpretation. URL below.Second live stream/podcast will be put up tomorrow. URL below .Couple big thank yous from prominent science writers - NYT /WSJ - said learned more listening to youfor 30 minutes then everything they read in the last few weeks.My response when you have a very wise scientist, who hears the question and answers the question,and has 40+ years of experience we should listen and learn.Be well.HCBHoward Bauchner, MDEditor in Chief of JAMA and the JAMA Netwo rkPlease respect the confidentiality of t his emaillisten to my chats with author sFrom: Karen Adams- Taylor <Karen.Adams-Taylor@ama-assn .org>Date : Thursday, February 6, 2020 at 4:59 PMTo: Howard Bauchner <Howard .Bauchner@ jamanetwork.org >, Annette Flanagin<Annette .Flanag in@jamanetwork.o rg>, Michae l Berkwits<Michael.Berkwits@jamanetwo rk.org>, Tom Easley <Tom .Easley@ama-assn.org >, Brian Shields<Brian.Shields@ama -assn.o rg>, Betsy Solaro <Elizabeth .Solaro@ama -assn.o rg>, Sean O'DonnellNIH-002097<Sean. O' Donnel l@a ma-assn. org>, Tiffany Jones <Tiffany .J ones@a ma-assn.erg>Subject : Subtitled Coronav irus VideoThe 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alertThe 2/6 Fauci update video will go to the trans lator tomorrow.-KarenKaren Adams-TaylorVice President, Publishing Production OperationsJAMA Network ™330 N Wabash Ave, Ste 39300, Chicago, IL 60611T -----(b)(6) jamanetwork.comNIH-002098From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:00:35 +0000To: Greg Folkers (b)(6) ;Billet , Courtney (NIH/NIAID) [E];Routh,Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [ElSubject: FW: Subtitled Coronavirus VideofyiFrom: Howard Bauchner <Howard .Bauchner@jamanetwork.org>Se nt: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El (b)( >Subject: FW: Subti tled Coronavirus VideoTonyFirst live stream/podcast now with Chinese interpretation . URL below.Second live stream/podcast will be put up tomorrow . URL below.Couple big thank yous from prominent science writers - NYT /WSJ - said learned more listening to youfor 30 minutes then everything they read in the last few weeks.My response when you have a very wise scientist, who hears the question and answers the quest ion,and has 40+ years of experience we should listen and learn.Be well.HCBHoward Bauchner, MDEdito r in Chief of JAMA and the JAMA NetworkPlease respect the confidentiality of this emailListen to my chats with authorsFrom: Karen Adams-Tay lor <Karen.Adams -Taylor@ama -assn.org>Date: Thursday, February 6, 2020 at 4:59 PMTo: Howard Bauchner <Howa rd.Bauchner@jamanetwork .org>, Annette Flanagin<Annette .Flanagin@jamanetwork.org >, Michae l Berkwits<Michael.Berkw its@jamanetwork.org >, Tom Easley <Tom.Easley@ama -assn.org >, Brian Shields<Brian.Shields@ama-assn.org >, Betsy Solaro <Elizabeth .Solaro@ama -assn.org >, Sean O'Donnell<Sean.O'Donne ll @ama-assn.org>, Tiffany Jones <Tiffany.Jones@ama-assn .org>Subje ct: Subtitled Coronav irus VideoNIH-002099The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalertThe 2/6 Fauci update video will go to the trans lator tomorrow.-KarenKaren Adam s-TaylorVice President, Publishing Production OperationsJAMA Network rM330 N Wabash Ave, Ste 39300, Chicago, IL 60611T -----(b)(6) jamanetwork.comNIH-002100From: (b)(6)Sent: Thu, 6 Feb 202015:09:43 -0500To: Folkers, Greg (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea(NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E]Subject: Re: ASF --- Morens + Daszak +Taubeneberger paperI agree. I will not be a co-authorOn Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E]----------- CbH wrote:So the question to you - do you want to be part of this? ie be acoauthor(b) (4)I would vote no - it wud look weird to add you as a coauthor now. Plus,plate too full. .....Disclaimer: Any third-party material in this email has been shared for internal use under fairuse provisions of U.S. copyright law, without further verification of its accuracy/veracity. Itdoes not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S.governme nt.NIH-002104From:Sent:To:Cc:Subject:Thanks, Jim.Anthony S. Fauci , MDDirectorFauci, Anthony {NIH/NIAID) [E]Thu, 6 Feb 2020 17:36:11 +0000(b)(6)(b)(6)RE: nCoV: Heads-upNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX : (301 496-4409E-mai l (b)(The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: (b)(6) ------------------- Sent: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) -------------- --(b~)(6) Cc: (b) (6)Subject: nCoV: Heads-up. We will keep you updated. Best. John and JimFrench drugmaker Sanofi workin g on coronavirus initiativeCHINA-HEALTH/SANOFI (PIX):French drugmaker Sanofi working on coronavirusinitiativePARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiativewithin the next two weeks, its chief executive said on Thursday, adding that it wants to presentsomething concrete and not add to "fantasies".At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with thefast-spreading virus that has killed more than 500 people in China, but several have warned thatdevelopment of treatments will take time.NIH-002105NIH-002106"We have seen a flurry of activities from other companies," CEO Paul Hudson told a newsconference after Sanofi published 2019 results on Thursday."We are one of the few companies that has the expe1iise to know when it is just a fantasy, orwhen it could be real. In the next week or two, you will see something more confinnatory aboutthe approach we will take."Hudson declined to give further details.Sanofi had already said it was sharing its expertise and data acquired from other outbreaks withthe Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotechbusinesses to try to develop a vaccine candidate for the coronavirus.Britain's GlaxoSmithKline is also collaborating with CEPI."The objective here is not a newspaper headline, it is real work that will make a difference ,"Hudson said.(Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman)From:Sent:To:Cc:Subject:Attachments:Fred:Fauci, Anthony (NIH/NIAIO) [E)Thu, 6 Feb 2020 16:28:04 +0000h iattf@washpost.comRedfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E]Proposed OpEdRedfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docxI hope that all is well with you . (b)(6)-------------------- (bH6J. Within this context, Bob Redfield and I have written an OpEd on the government response to the novel coronavirusoutbreak. Would the Post have any interest in this? Many thanks.Best regards ,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not express ly made onbehalf of the NIAID by one of its representatives .NIH-002107From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Thu, 6 Feb 2020 14:34:57 +0000To: Billet, Courtney (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary(NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E]Subject: RE: Requested coronavirus talking points for press conferenceAttachments : Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 -Fauci Press remarks with tracked edits.docxOooops! Forgot the attachment. Here it is.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave rece ived this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From : Fauci, Anthony (NIH/NIAID) [E]Sent: Thursday, February 6, 2020 9:34 AM ------~= To: Billet, Courtney (NIH/NIAID) [E) (b)(6)Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E](b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer"(: N"":"l.'H."".-/'::N":"-.I"A'."l'D"':.")': :-[:~E:]-====-.:--_.;.. (bc)(-=c ; Stover, Kathy ( NI H/NIAI D) [E] (b)( >Subject: RE: Requested coronav irus talking points for press conferenceHere is my revised and updated press remarks with my tracked edits showing.Please accept edits, do a spell and grammar check and resubmit. Also, put a copyin my fol der . Thanks.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone : (b)(6)NIH-002114FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [El (b)(6)Sent: Thursday, February 6, 2020 9:16 AMTo: Fauci, Anthony (NIH/NIAID) [E]------= (b')"("=6)>Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)1>; Folkers, Greg (NIH/NIAID) [E](b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer"(: N"":"1.:H"-:/7'-N".I"A'.'"l"-D'':::)': --:[~E:l-===~--~ (b")"(",6=' ),;; Stover, Kathy ( NI H/NIAI D) [El (b)(6)Subject: FW: Requested coronavirus talking points for press conferenceHHS has asked us for your talking points fo r the press conference by 11am. We were planning toresubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of whatyou would say. This is not a script.Is it OK for us to send th is to Bill?From: Selgrade, Sara (NIH/NIAID) [El (b)( >Sent: Thursday, February 6, 2020 8:37 AMTo: Fauci, Anthony (NIH/NIAID) [E] _____ "("b")'"("=6)Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E](b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg(NIH/NIAID) [El (b)(6)Subject: Requested coronavirus talking points for press conferenceDr. Fauci,Attached please find the requested talking points from your last coronavirus press conference.Please let us know if you need anything else .Thanks,SaraNIH-002115From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Thu, 6 Feb 2020 10:58:13 +0000To: Collins, Francis (NIH/OD) [ElCc: Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conrad,Patricia {NIH/NIAID) [ElSubject: RE: Follow up on Addis MeetingFrancis:Thanks for the note . Best to have Trevor have his program person who will be leading thiseffort contact Cristina Cassetti in DMID. Cristina and Emily Erbelding could do all of thenecessary and approp riate coordination .Thanks,TonyFrom: Coll ins, Francis (NIH/OD) [El -------- (b)(6) Sent: Thur sday, February 6, 2020 4:56 AM -------=-,--=" To: Fauci, Anthony {NIH/NIAID) [El --------(b)(6) Subject: FW: Follow up on Addis MeetingSee reference to coronav irus research in the note from Trevor. How would you like tocoordinate this?FCFrom: Trevor Mundel (b)(6)> _____________ ..,Sent : Wed nesday, February 5, 2020 10:55 PMTo: Collins, Francis (NIH/OD) [ElCc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- (b,H;,;;6; ;J;;--G: :-la:-s"s, Roger {NIH/FIC) [El(b)(6)Kedest Tesfagiorgis (b)(6)>Subject: Re: Follow up on Add is Meeting(b)(6);That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirusreponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so wemight want a quick call in the next few days to thin k about how we coordinat e this - I've been in touchwith Jeremy as we ll. TrevorTrevor Mu ndel, MD, PhDPresident , Global Health ProgramV (b)(F +1.206 .494 .7041E (b)((ij -------------(b)(6)Execut ive AssistantOffice of the President, Global HealthNIH-002118(b)(6)(b)(6)Bill & Melinda Gates Foundationwww .gatesfounda tion.org(b)(6)From: Collins, Francis (NIH/OD) [El (b)(6)>Sent : Wednesday, February 5, 2020 3:11 PMTo: Trevor MundelCc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [ElSubject: RE: Follow up on Addis MeetingHey Trevor,This is an excellent development. How about I send you a proposal of possible CARI TPs forElioda - in the next 24 hours?Franc isFrom: Trevor Mundel (b)(6)Sent : Wednesday, February 5, 2020 4:43 PMTo: Tumwesigye Elioda CbH6l>; Collins, Francis (NIH/OD) [El -------- (b) ( >Cc: (b)(6)Subject: Re: Follow up on Addis MeetingThat's great to hear Elioda and congratulations, many thanks for letting us know . We will certain ly getback to you shortly to enlist your help with the CARI initiative at AU level.Warm regards,TrevorFrom: Tumwesigye Elioda (b)( >Sent : Wednesday, February 5, 2020 1:16 PMTo: Trevor Mundel; Francis CollinsCc: (b)(6)Subject: Follow up on Addis MeetingDear Trevor,Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meetingin Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARIInitiative and the need to support research, entrepreneurship and innovation in a big way in Africa. Wealso explored the mechanism for CARI Funding. We were also looking for a mechanism to reach theCommittee of Ten (ClO) Heads of State and Government championing Education, Science andTechnology in Africa.NIH-002119Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers ofEducation and of Science and Technology in all the 55 Members States in Africa. We do this under theSpecialized Technical Committee on Education, Science and Technology (STC-EST). This Saturday on 8thFeb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0.The purpose of this message is to let you know of my added responsibilities and related opportunities aswell as seek for any update or latest information regarding the CARI init iative . I look forward tointensified communication and collaboration.RegardsDr. Elioda TumwesigyeMinister Science, Technology and InnovationRepublic of UgandaTel: (b)(6)Sent from my iPadNIH-002120From: Fauci, Anthony (NIH/NIAID) [ElSent : Thu, 6 Feb 2020 04:10:50 +0000To: Cassetti, Cristina (NIH/N IAID) [ElCc: Conrad, Patricia (NIH/NIAID) [ElSubject: FW: PandemicThreat Reduct ionSimil ar e-Omail from Dr. Tubb.From: Richard Tubb ------- (b)(6)> Sent : Thursday, January 30, 2020 11:35 AM_To..:.. =!==~~----- C_>bC6)F auci, Ant hony (NIH/N IAID) [E](b)(6)Subject: Fwd: Pandemic Threat ReductionGood morning Tony.Given your most recent appointment , I wanted to showyou the courtesy of letting you know what I have alreadyprovided to senior leaders at the White House regarding apossible mitigating strategy until the definitive solution tothe CoV is available and implemented. The string belowincludes additional information as to how titanium dioxidecan fit into both the White House and theNational / International solutions, and the open-sourcewebsite for the company. Please keep in mind thatbecause this product is already approved and in use in theEU for a variety of commercial uses, the data provideddoes not specifically address the applications I, and you,are interested in. Ho-\iveve, rwith a deep understanding ofthe White House mission, I can say that there is not a bigleap in that thought migration.Dr. Jackson has already provided the same material tosome of your White House Commission colleagues. I willalso be reaching out to another friend of mine from theBush-now-Trump Administration, Steve Biegun.NIH-002121I encourage your representatives to meet with thecompany leadership and scientists while they are in the USnext week. Please let me know if you have any questionsthat I can address. Thank you for once again stepping upto the plate for our Country.v/rDickps .. .I remembered this morning where you and I lastspoke--Bush (41) funeral.---------- Forwarded message --------From:Richard Tubb ----------- (b) (6) > Date: Thu, Jan 30, 2020 at 8:54 AMSubject: Re: Pandemic Threat ReductionGood morning Gentlemen,I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation.First, the company's joint venture partner in India is meeting with the Indian government as we speak.It appears likely that in light of the news of India's introduction to the corona virus the government willutilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute acontract with this company.Secondly, I will attach the open source web site for the company to provide you background informationthat, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It'simportant to note a couple of things:This product is already proved and is in use in the EU with all the approvals appropriate for the same.Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues todecontamina te and disinfect in the background for up to 1-5 years before retreating. (Depending on thetype of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective thanwhat the application normally would use, e.g. in a hotel-cont inues). The chemical treats anythingorganic, I.e. bacteria, viruses, voe, bio threats, etc. because it is a catalyst, it is neither used up, norNIH-002122does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g,airplanes and government cri tical infrastructures) and the air around the surface (and HVAC fi lters andair handlers).The leadership will be in DC next week. I highly encourage any and all potential stakeholders make timeto meet with them while they are here. To that end, I had already emailed Dr. Fauci (with whom Iworked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement ofhis participat ion on the new coronavirus commission, I will also reach out to an old friend and colleagueSteve BIEGUN now that he is in the commission . Please feel free to forward the information to others asyou deem appropr iate .Thanks,Dick Tubbhtt ps://act.g lobal/Ps ... once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimesagainst the dictionary .Sent from my iPadOn Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote:Gentlemen, Brother s, and Others ...This is Dick Tubb , writing on behalf ofAdmiral Jack son and Dr. Hofmann (bothcopied herein). It feels like "old times"- -I'mundecid ed as to wheth er they are good oldtimes , or otherwise. Regardless , it does feellike we've been down a very simil ar roadbefore. Perh aps we can apply some of thelessons -learned to th e inevitable problemsahead.NIH-002123NIH-002124In light of the current and evolving threatpresented by the corona virus, I am writingto you as a courtesy to inform you of aproject that Admiral Jackson, Dr.Hofmann, and I have been consulting on.We believe so strongly in the technology,people, and potential that we have beenconsulting pro bono and currently have nofinancial stake in the project. While notdeveloped specifically designed for suchpurposes, I increasingly believe that until avaccination and treatment for the coronavirus is available, this technology may bethe last best chance in containing, anderadicating the virus, thereby protectingthe homeland, our economy, the Continuityof the Presidency, an EnduringConstitutional Government, our people andour Country. Moreover, reverting to my"lessons-learned, problems-ahead"statement, even after this crisis is over, anda vaccine and treatment procured, it willonly be a matter of time until "next time."This letter is proof-positive of that reality.My experiences, especially in the early2ooo's (e.g. anthrax and other biothreats,SARs, etc.) underpin my beliefs.The technology that provides the solution,both now and in the future, involves aunique formulation of a photo catalyticNIH-002125nano titanium dioxide solution (the AirForce guys will, of course, understand whatthat means, so you non-Air Force folks, justbuy them a beer and they'll explain it toyou) that is safer, more effective, and morecost effective than any other solution. Itwas developed and approved in the EU, andI have asked the senior leadership of thecompany to come to Washington DC nextweek. Dr. Hofmann and I spent the dayyesterday with a Chinese "titan" respectedby and with access to the most seniorgovernment officials, academic and medicalgiants, and investment and industrycaptains. I have encouraged , and he hasagreed in principal, to follow ourrecommendations as they relate to theirlargest airline, and their key facilities.In short, our strategic priority is to firstfortify the weak link in the pandemic chain:the airlines. Doing so will provide the timenecessary to isolate, contain, and ultimatelydestroy the threat at its source(Wuhan) ,and in its home (China). AsPresident Bush so commonly stated about avery different threat, we need to fight thebattle over there, so that we don't have tofight the battle here. Although PresidentBush was a true believer in the threat of apandemic, I believe this threat, and theNIH-002126threats that are surely to fallow are, inreality , many, many times greater than thethreat he envisioned when making thatstatement. By fighting a possibleimpending pandemic at its source we willpreserve and protect the safety andconfidence of our people, and the strengthof our economy.Once we have interrupted the threat supplychain, we can then shore up our criticalinfrastructure using the same technologyand process, then assist the Chinese inaddressing their challenges, and protectour international allies elsewhere . In thatvein, in addition to the Chinese, I have alsodiscussed this technology and strategy withsenior proxies for another of my formerpatients, His Royal Highness, the CrownPrince of Saudi Arabia, and his father, theKing.As I noted above , I have asked theleadership of the company to come toWashington (from Germany and Denmark)next week for a variety of meetings. WhileAdmiral Jackson will be "tied up in Texas"for the foreseeable future, please let meknow if you would like to meet with myselfor Dr. Hofmann, or the companyNIH-002127leadership while they are here, to learnmore.Thank you and my best to you all as youplan for and continue to protect ourCountry,Very Respectfully,Dick Tubbps. For your SA, I have also attached belowthe latest sit rep on the coronavirus.Richard J. Tubb, MDBrigadier General (retired)White House Physician EmeritusShoreland's Travax News Alert ServiceAbbreviatedChina: More than 2,800 Cases of 2019-nCoV in 30Provinces/Municipalities , Mainly in Wuhan ; CasesExported to 16 CountriesWHAT'S NEWAccording to regional health authorities, more than 1,800 additional ,confirmed cases (including 25 deaths) of pneumonia caused by 2019novel coronavirus (2019-nCoV) have been reported since January 27,2020, throughout the country, mainly in the provinces of Hubei (1,291),Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and inthe cities of Chongqing (132), Beijing (19), and Shanghai (13). Most newcases had a travel history to Wuhan . Almost all the recent deaths occurredin Hubei Province. Twenty more patients have recovered and beenNIH-002128discharged. More than 4,600 confirmed cases (including> 100 deaths)have occurred since December 8, 2019.A total of 13 additional , exported, confirmed cases have been reported(through January 28, 2:00 p.m. EST) since Monday, January 27. Morethan 25 cases have been exported in the past 7 days. Cases reportedsince Monday arrived in the following countries on the dates shown:Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20and 21 ), France (arrival date unknown), and Thailand (arrival datesunknown). All of these cases had travel history to Wuhan or contact withan ill person from Wuhan while in China .In addition to these exported cases, 7 locally acquired cases have beenreported since Monday in Germany (4), Japan , Taiwan and Vietnam. Thecases in Japan, Taiwan , and Vietnam reported contact with an obviously illperson from China. In Germany all 4 cases had close contact in abusiness seminar with an apparently asymptomatic Chinese woman onJanuary 21 (who previously had contact with relatives from Wuhan) ; thewomen states symptom onset was on a flight to Shanghai on January 23,and she was later confirmed to have 2019-nCoV. Incubation periods inthese cases have been as short as 3 days. In light of the secondary casesin Germany in a business setting, the most cautious approach of havingarrivals stay at home or in a hotel for 14 days after their last possibleexposure in China is increasingly justified.Updated travel advisories include: 1) Australia: reconsider travel to China;2) Canada: avoid all travel to Hubei Province; 3) Finland: avoidnonessential travel to Hubei Province; 4) France: avoid all travel to HubeiProvince; 5) Germany: avoid nonessential travel to China and avoid alltravel to Hubei Province; 6) India: avoid all nonessential travel to China; 7)New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid allnonessential travel to China.Singapore now denies entry to residents of Hubei Province and those whohave traveled there in the past 14 days.Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, YevreyskayaOblast) in Far Eastern Federal District, Russia have closed their landborders with China.Bangladesh , Canada, India, Kazakhstan , Russia, and South Korea arearranging flights to repatriate their respective citizens from Wuhan. Thesepersons will be closely monitored and present little threat of onwardtransmission.All tourist attractions in Tibet Autonomous Region have been closed .Current influenza vaccination is recommended to decrease the risk ofsimple influenza being mistaken for 2019-nCoV upon return.Infection control supplies have been depleted in medical facilities in thesmaller cities in central China; the situation is critical in many areas andresupply is uncertain.NIH-002129OVERALL RISK ASSESSMENTThe epidemic in China is months from peaking . A report indicates that justprior to the cordoning off of Wuhan, over 5 million residents (manypotentially infectious) left for other parts of China, and many thousands leftfor Hong Kong, Singapore, Thailand, and Japan. Exported cases have sofar been to countries likely to be capable of controlling (but not preventing)ongoing transmission, which will inevitably occur. In light of the secondarycases in Germany in a business setting , the most cautious approach ofhaving arrivals stay at home or in a hotel for 14 days after their lastpossible exposure in China is increasingly justified.Based on increasing data on virology, clinical presentation, andtransmission, this coronavirus closely resembles SARS-CoV in manybehaviors. Fortunately , sequential sequencing of viral isolates over timeindicate no significant new viral mutations ; mutations often increasetransmission or virulence . WHO assesses the risk of this event to be veryhigh in China , high at the regional level, and high at the global level. Theclosing of Wuhan airport and the major cities of Hubei province have yet tostem the flow of exported cases . The originally implicated animal market,now closed indefinitely, bears little relevance to the ongoing situation.Whether the market was the focus of a species jump from animals tohumans or merely one of multiple amplification settings for initial cases isincreasingly unclear. The degree of human-to-human spread outside ofHubei province remains unclear . A reproductive number, Ro, is estimatedat 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Rogreater than 1 indicates that each case leads to more than 1 subsequentcase, making control much more difficult. The spectrum of diseasemanifestations in a large cohort study has yet to be disclosed; a severecase rate of 20% has been consistent. The existence of mildlysymptomatic and asymptomatic infectious cases could increase the risk ofglobal spread. Case fatality is impossible to ascertain at present, andlesser or greater clinical virulence compared to MERS-CoV or SARS-CoVremains speculative.See 20 19 Novel Coronav irus Outbreak for detailed information .© 2020 Shoreland , Inc. All rights reserved .Travax News Alert items are incorporated into Shoreland's subscriptions .Travax content represents decision-relevant, expert synthesis of real-timedata reconciled with new and existing available advice from authoritativenational and international bodies .For email service changes , please forward this message toservice@shore land.com with your request. If the change should apply toall email subscriptions (Content Changes , Literature Watch and NewsAlert), please specify that in your request. [Account: SI53213; Recipient:bg.richard.tubb@gmail.com)NIH-0021302019 Novel Coronavirus Outbreak ReportcomprehensiveLast updated January 28, 2020.What's NewAccording to regional health authorities, more than 1,800 additional, confirmed cases(including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV)have been reported since January 27, 2020, throughout the country, mainly in theprovinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan(143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most newcases had a travel history to Wuhan. Almost all the recent deaths occurred in HubeiProvince. Twenty more patients have recovered and been discharged. More than 4,600confirmed cases (including> 100 deaths) have occurred since December 8, 2019.A total of 13 additional, exported, confirmed cases have been reported (throughJanuary 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have beenexported in the past 7 days. Cases reported since Monday arrived in the followingcountries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22),Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival datesunknown) . All of these cases had travel history to Wuhan or contact with an ill personfrom Wuhan while in China.In addition to these exported cases , 7 locally acquired cases have been reported sinceMonday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan,and Vietnam reported contact with an obviously ill person from China. In Germany , all 4cases had close contact in a business seminar with an apparently asymptomaticChinese woman on January 21 (who previously had contact with relatives from Wuhan);the woman states symptom onset was on a flight to Shanghai on January 23, and shewas later confirmed to have 2019-nCoV. Incubation periods in these cases have beenas short as 3 days. In light of the secondary cases in Germany in a business setting,the most cautious approach of having arrivals stay at home or in a hotel for 14 daysafter their last possible exposure in China is increasingly justified .Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada:avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to HubeiProvince ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessentialtravel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessentialtravel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid allnonessential travel to China .Singapore now denies entry to residents of Hubei Province and those who havetraveled there in the past 14 days.Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) inFar Eastern Federal District, Russia have closed their land borders with China .Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flightsto repatriate their respective citizens from Wuhan. These persons will be closelymonitored and present little threat of onward transmission.NIH-002131All tourist attractions in Tibet Autonomous Region have been closed.Current influenza vaccination is recommended to decrease the risk of simple influenzabeing mistaken for 2019-nCoV upon return.Infection control supplies have been depleted in medical facilities in the smaller cities incentral China; the situation is critical in many areas and resupply is uncertain.Overall Risk AssessmentThe epidemic in China is months from peaking. A report indicates that just prior to thecordoning off of Wuhan, over 5 million residents (many potentially infectious) left forother parts of China, and many thousands left for Hong Kong, Singapore, Thailand, andJapan. Exported cases have so far been to countries likely to be capable of controlling(but not preventing) ongoing transmission, which will inevitably occur. In light of thesecondary cases in Germany in a business setting, the most cautious approach ofhaving arrivals stay at home or in a hotel for 14 days after their last possible exposurein China is increasingly justified.Based on increasing data on virology, clinical presentation , and transmission, thiscoronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequentialsequencing of viral isolates over time indicates no significant new viral mutations;mutations often increase transmission or virulence. WHO assesses the risk of this eventto be very high in China , high at the regional level , and high at the global level. Theclosing of Wuhan airport and the major cities of Hubei province have yet to stem theflow of exported cases. The originally implicated animal market , now closed indefinitely ,bears little relevance to the ongoing situation. Whether the market was the focus of aspecies jump from animals to humans or merely one of multiple amplification settingsfor initial cases is increasingly unclear . The degree of human-to-human spread outsideof Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.4-2.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1indicates that each case leads to more than 1 subsequent case, making control muchmore difficult. The spectrum of disease manifestations in a large cohort study has yet tobe disclosed; a severe case rate of 20% has been consistent. The existence of mildlysymptomatic and asymptomatic infectious cases could increase the risk of globalspread . Case fatality is impossible to ascertain at present , and lesser or greater clinicalvirulence compared to MERS-CoV or SARS-CoV remains speculative .Current Disease SituationMore than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) haveoccurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly inWuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui(106); in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 otherprovinces throughout the country. An additional 6,900 suspected cases have beenreported since January 21, 2020. In the setting of a large outbreak and with increaseddelays in testing, a high proportion of suspected cases will evolve into confirmed cases.Seventy-nine cases have been discharged. Two-thirds of the cases are male. Theyoungest case is 10 years old and the oldest is 89; more than 70% of cases are over 40years old, but the co-morbidity profiles of most cases are unknown .NIH-002132The number of persons becoming infected with the virus has been doubling every sixdays. The outbreak in China is not approaching peak, and modeling indicates that ismonths away.Exported CasesSeventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented atinternational ports of entry January 6-25 in 16 countries. Of these cases, more than 25cases arrived in the past 7 days.All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in Chinaand symptom onset dates after December 31, 2019; none had visited the implicatedmarket.Australia (5 cases): One case traveled while asymptomatic aboard China SouthernAirlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalizedon January 23. Contact tracing is underway; movement around Melbourne was limitedprior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights toSydney, New South Wales State on January 6, 18, 20, and 23, and were hospitalizedon January 15, 20, and 24. One of the patients had limited movement around Sydneyprior to isolation; movement history for the other 3 cases is unknown.Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukvilleon January 23, 2020, and developed symptoms on January 25.Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlinesflight CZ311 to Toronto, Ontario Province on January 22. The first case wassymptomatic while traveling and was hospitalized on January 23. The second case wasunder self-isolation and was confirmed on January 27. Contact tracing is underway;patient movement around Toronto was limited prior to isolation .France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris onJanuary 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travelhistory for the fourth case in unknown. All cases were hospitalized.Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25;the first aboard a train to West Kowloon, the second aboard a flight to Hong KongInternational Airport , and the third to Lo Wu Control Point. Four of the cases traveledwhile asymptomatic aboard trains on January 19 and 22. The last case traveled withdiminished symptoms aboard a train on January 23. All cases were hospitalized .Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight toKanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January19. The first was hospitalized on January 10 and discharged on January 15 followingrecovery, and the second was hospitalized on January 22. Another 2 cases traveledwhile asymptomatic: the first aboard a flight to Tokyo on January 18 and the secondaboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January23, and the second was hospitalized on January 24. The remaining 2 cases arrived onJanuary 20 and 21 in Aichi and Tokyo prefectures.Macau (7 cases): The first case traveled while asymptomatic aboard a train and a buson January 19, and the second case traveled while symptomatic (travel methodunknown) on January 22. The first case was hospitalized on January 19 and the secondNIH-002133case on January 21. The third case traveled aboard a ferry on January 23 and wasimmediately hospitalized. Three cases traveled (methods unknown) on January 22; allwere hospitalized. The last case traveled while asymptomatic on January 23 and washospitalized January 27.Malaysia (4 cases) : The first case traveled while asymptomatic aboard a bus to JoharBaharu on January 22 and was hospitalized on January 23. The remaining 3 casestraveled (method unknown) to Johar Baharu on January 23; all were hospitalized .Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized onJanuary 13, and was discharged on January 17 following recovery.Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights onJanuary 18, 19, 20, 21, 22, and 23.South Korea (4 cases): Two cases traveled while symptomatic to lncheon InternationalAirport and to Gimpo International Airport on January 19 and 23, and both wereimmediately hospitalized. The remaining cases traveled while asymptomatic on January20 and were hospitalized on January 25.Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, anddeveloped symptoms on January 25.Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 casesarrived at Taiwan Taoyuan International Airport.Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airporton January 8, 13, and 19 and were hospitalized; the travel history of the fourth case isunknown. The fifth case traveled to Bangkok on January 21 and was hospitalized onJanuary 23. The travel histories of the remaining 9 cases are unknown.U.S. (5 cases): Two cases traveled while asymptomatic: the first to O'Hare Internationa lAirport on January 13 and the second to Seattle-Tacoma International Airport onJanuary 15. The first was hospitalized several days after arrival, and the second washospitalized on January 19. The remaining 3 cases were reported in Maricopa County,Arizona and Los Angeles and Orange counties, California ; information on the patients'travel histories are unknown. Contact tracing for all cases is underway. The first casereported limited movement around Chicago prior to hospitalization; movement historyfor the other 2 cases in unknown.Vietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized onJanuary 22 in Ho Chi Minh City.In addition to these exported cases, 7 locally acquired cases have been reported sinceMonday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan,and Vietnam reported contact with an obviously ill person from China. In Germany, all 4cases had close contact in a business seminar with an apparently asymptoma ticChinese woman on January 21 (who previously had contact with relatives from Wuhan);the woman states symptom onset was on a flight to Shanghai on January 23, and shewas later confirmed to have 2019-nCoV . Incubation periods in these cases have beenas short as 3 days.Entry/Exit ScreeningNIH-002134In a reversal of long-standing policy, WHO now recommends that all countriesimplement temperature screening at points of entry for passengers arriving from 2019-nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunicationmessages at points of entry to later capture asymptomatic persons whoare in the incubation phase.In early January , some exit screening was implemented at Wuhan Tianhe InternationalAirport (nonstop flights to Istanbul, London, New York, Osaka, Paris, Rome, SanFrancisco, Tokyo, and major hubs throughout Southeast Asia), as well as at 3 major railstations in Wuhan . More restrictive screening was instituted on January 15 in Hubeiuntil cessation of international flights on January 23. Despite exit screening at allinternational airports in China in the past week, significant numbers of cases continue tobe exported.Entry screening at international ports of entry has been or is being implemented asnoted below, and anyone with fever and respiratory symptoms who has been to 2019-nCoV-affected areas in the previous 14 days will be detained and isolated at theselocations:Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , OranAhmed Ben Balla AirportBurma (Myanmar) : Yangon International AirportEgypt: Cairo International Airport (all flights from China)Hong Kong: All border checkpoints , including Hong Kong Internationa l Airport and therailway station in West KowloonIndia: Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai internationalairports (all flights from China and Hong Kong)Italy: Leonardo da Vinci-Fiumicino AirportIran: Tehran Imam Khomeini International Airport (all flights from China)Macau: Macau International AirportNorth Macedonia: Skopje International Airport (connecting flights from Asia)Qatar: Hamad International Airport (all flights from China)Russia: Moscow, Irkutsk Oblast, and Yekaterinburg international airports and points ofentry in Amur OblastSingapore : Changi AirportSouth Africa : O.R. Tambo International Airport (all flights from China)South Korea: lncheon International AirportTaiwan: All international airportsNIH-002135Thailand : Krabi, Suvarnabhumi, Don Mueang, Phuket, and Chiang Mai airportsTurkey: All international airports (all flights from China)United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport(all flights from China)U.K.: Heathrow International AirportU.S.: Twenty points of entry, including Hartsfield-Jackson Atlanta International Airport,John F. Kennedy International Airport, Los Angeles International Airport , O'HareInternational Airport , and San Francisco International Airport. Travelers from Wuhanmay have their temperatures taken and/or be required to complete a symptomquestionnaire; travelers with symptoms (fever, cough, difficulty breathing) will bedeta ined for additional assessment.Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana,Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal,Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka,Tajikistan, Tunisia, Vietnam : Airports and other ports of entryTravel AdvisoriesThe following countries and/or organizations have published travel recommendations:Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France ,Germany , Japan, Mexico , New Zealand , U.K., U.S.Avoid Nonessential Travel to Hubei Province: Finland, UkraineAvoid All Travel to China: None at presentAvoid Nonessential Travel to China: Australia, Germany, India, Taiwan , U.S.No Advisory: WHOTravel RestrictionsDifferent levels of travel restrictions are in effect:No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air SeoulNo Flights from Wuhan: Wuhan Airport is closed to all international and domesticflights.Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea, Russia (AmurOblast , Khabarovsk Krai, Jewish Autonomous Oblast in Far Eastern Federal District);high speed rails and ferry services suspended in Hong KongNo Residents from Hubei Province: Hong Kong, Macau, and Singapore (includingvisitors in past 14 days), Malaysia , and TaiwanNIH-002136Internal Travel Restrictions in China: Major cities in Hubei Province have instituted atravel ban on occupants of their cities, suspending urban buses, subways , ferries , andlong-distance passenger transport from the cities, including flights and trains , andclosing intercity roads. lnterprovince shuttle buses in major areas have stopped. Manybars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , andmany other affected areas. Major tourist attractions have closed in Beijing, Shanghai ,Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China hasstopped all inbound and outbound tour groups but not individual travel. Internal travelfor the Lunar New Year Holiday has been severely limited by the government , andpublic gatherings are forbidden. The reopening of schools and universities has beenpostponed in many areas. Shanghai has temporarily closed all nonessentialworkplaces. Visitors from Hubei Province will be actively monitored for 14 days inHaikou, Hainan Province.No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa mustspend at least 14 days in a country free of 2019-nCoV and undergo medical clearanceprior to travel to Samoa.Australia , Bangladesh, Belgium, Canada, France, Germany, India, Japan, Kazakhstan ,Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. arearranging flights to repatriate their respective citizens from Wuhan. These persons willbe closely monitored and present little threat of onward transmission .TransmissionThe detailed epidemiology of possible causative animal exposures and zoonotictransmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked toSouth China Seafood City market in Jianghan District, which sold seafood and otherwildlife (including birds). More than 580 environmental samples, without indication as towhether animal tissue was included , were collected from the implicated market. Ofthese , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-originpoint of the large-scale outbreak. Thirty-one of the positive samples (94%) werecollected from the western part of the market, where wildlife was traded. The firstpublished epi-curve shows that the symptom onset date of the first patient identified inthe outbreak was December 1, 2019. The patient reported no exposure to theimplicated market; no epidemiological link has been detected between this case andlater cases. This finding raises the possibility of an initial jump of 2019-nCoV directlyfrom bat to human, with subsequent initial human-to-human propagation within theseafood market.Infected intermediate animal hosts, if they exist, may still be present in the supply chain.South China Seafood City market, now closed indefinitely , remained in operationthrough December 31, 2019. Other points of infection would be likely because manysubsequent cases had no contact with the implicated market. Chinese authorities havenow stated that human-to-human transmission is in the fourth generation in Wuhan andat least the second generation elsewhere (mostly in clusters). A reproductive number,Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists.An R0greater than 1 indicates that each case leads to more than 1 subsequent case,making control much more difficult. Ro is not a constant number and changes with theongoing circumstances and evolution of an outbreak . One published cluster studyindicates asymptomatic shedding (but not transmission) by a single patient. Sequencedata from several small clusters indicate identical virus in all subjects within the cluster.NIH-002137More than 47,800 close contacts remain under surveillance (> 1,200 have beenreleased), and contact tracing is ongoing in affected provinces and municipalities.However, not all contacts are being ascertained or monitored adequately. As many as16 health care workers (HCWs) have been confirmed as infected by at least 1 case inWuhan in a potential super-spreading event, but overall infectivity for HCWs has notbeen established. No case of 2019-nCoV has been attributed to transmission on anaircraft .The survival rate of the virus on surfaces or in the environment is unknown. Disinfectionprocesses that are effective for other zoonotic coronaviruses should be followed fornow. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs,bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, cleanany surfaces that may have blood, bodily fluids, and/or secretions or excretions onthem. Use a diluted bleach solution or a household disinfectant with a label that says"EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l(1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) ofwater.Clinical ManifestationsMost cases have reportedly exhibited symptoms of fever, respiratory compromise, andbilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan.Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sorethroat) and diarrhea are not common. Overall, about 20% of the cases have beensevere or critical, including pneumonia , respiratory failure, and in some cases death.The existence of asymptomatic cases has not been ascertained. No known treatmentexists for 2019-nCoV, although remdesivir will be available shortly from the U.S. CDCfor compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir,ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlierliterature , the combined use of lopinavir and ritonavir is under study in China. Currentinfluenza vaccination is recommended to decrease the risk of simple influenza beingmistaken for 2019-nCoV upon return.In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58)conducted early in the epidemic (presentation before January 2), the most commonsymptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue(44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglassopacity with subsegmental areas of consolidation, whereas ICU patients hadbilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even inthis early cohort) had been exposed to the South China Seafood City market. The casefatalityrate was estimated to be 15%, but more severe cases tend to predominate earlyin an epidemic. Limited data from another published cluster study indicate a 3- to 6-dayincubation period similar to SARS-CoV and clinical and radiologic features similar toSARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1to 14 days.Virology2019-nCoV was initially isolated from 1 case and entirely sequenced; this informationwas published internationally by Chinese scientists on January 10. Electron microscopyof 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventhNIH-002138member of the family of coronaviruses that infect humans. Novel coronaviruses fromWuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage Bof the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoVand SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with asimilarity between different gene segments ranging from 60% to 90%. 2019-nCoVexhibits a 96.5% similarity to the known bat coronavirus precursors in the same viralclade.Sequence data allowed national laboratories to rapidly develop diagnostic kits, whichare now available in most developed countries and most Asian countries. HKU1, NL63,229E, and OC43 are human coronaviruses that are detected by some routine multiplexPCR panels used in routine clinical practice. These coronaviruses are associated withminor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV,and 2019-nCoV , these agents are not associated with major outbreaks or severerespiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings sofar strongly favor (but do not prove) causation. 2019-nCoV has been shown to use thesame cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lowerrespiratory tract specimens, which should be the primary specimen obtained. Predictionof human-to -human transmissibility from sequence data is difficult becausecoronaviruses vary widely in their transmissibility; coronaviruses acquired from animalsgenerally have some potential for human-to-human transmission. Evidence fromsubsequent whole genome sequences acquired over the last several weeks show littlegenetic variation, indicating that the virus jumped from an animal reservoir to humanswithin the last few months. Identical recent mutations in epidemiologically unlinkedcases support sustained human-to-human transmission.Criteria for Testing of Suspected CasesU.S. CDCPersons meeting the following criteria (clinical features and epidemiologic risk) forsuspected cases of 2019-nCoV will be considered persons under investigation (PUI):• Fever and symptoms of lower respiratory illness (e.g., cough, shortness ofbreath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoVwhile that person was ill in the past 14 days before symptom onset• Fever or symptoms of lower respiratory illness (e.g., cough, shortness ofbreath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past14 days before symptom onsetHCWs entering the room with a PUI should use standard precautions, contactprecautions , airborne precautions , and eye protection (e.g., goggles or a face shield).PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they areidentified and be evaluated in a private room with the door closed, ideally an airborneinfectionisolation room if available.PreventionTravelers going to Wuhan should avoid animals (alive or dead), animal markets,products that come from animals (such as uncooked meat), and contact with illappearingpersons. Quality of infection control at medical facilities in Wuhan isuncertain, and those with minor medical problems should avoid busy medical settings.NIH-002139Infection control supplies have been depleted in medical facilities in the smaller cities incentral China; the situation is critical in many areas and resupply is uncertain. Travelerswho develop fever and respiratory symptoms within 14 days of travel to Wuhan shouldimmediately be isolated, and public health authorities should be alerted.Employees, Students , Visitors , All Others Coming from WuhanWhether asymptomatic individuals infected with 2019-nCoV are infectious to others isunknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset.SARS-CoV did not transmit until 4 days after symptom onset, which led to itseradication because all contacts with fever could be promptly identified and isolated.If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitorby taking a temperature reading immediately prior to coming into the workplaceor school for 14 days after their last exposure in Wuhan. Arrivals with fever at any timeshould self-report to public health authorities (or telephone ahead before presenting toa hospital) and should wear a mask as soon as possible. A more stringent approachwould require that an employee, student, or visitor-upon arrival to a workplace orschool- be instructed to perform an additional temperature check in the presence ofmedical personnel to ensure compliance with local self-monitoring requirements. Inaddition, prior to any gathering of~ 2 persons, attendees could be required to performadditional self-monitoring .Based on advanced information and employee or visitor medical screening, additionalpreventive measures may be required (e.g., increased ventilation, larger meeting roomswith more personal space per participant , disinfection of work areas and lavatories, andprovision of alcohol wipes).The most cautious approach would be for arrivals to stay at home or in a hotel for 14days after their last possible exposure in China. To date, all known cases exported toother countries had either visited Wuhan or had contact with an ill person from Wuhanwhile in China.Sent from my magical iPad!On Jan 29, 2020, at 2:46 PM, Richard Tubb <bg.richard.tubb@gmai l.com>wrote:Richard J. Tubb, MDBrigadier General (retired)White House Physician EmeritusFrom:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAID) [E)Thu, 6 Feb 2020 04:03:31 +0000Howard BauchnerConrad, Patricia (NIH/NIAID) [ElRE:Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawedThanks, Howard. Talk soon.-----Original Message-----From: Howard Bauchner <Howar d.Bauch11er@jamanetwork .org>Sent: Wednesday , February 5, 2020 6:37 AMTo : Fauci , Anthony (NTTI/NIAID) [E] ------~~Cc : Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,...Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+w i thout+ symptom s+was+ fl a wedThe author of our case-series - proof today will send to you - is an ICU doc in Wuhan - trained with Derek Angus -he has been great - but I have asked him about himself, bis family - we loss track of the personal - which is soimportant.J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couplemajor car accidents; etc. Also worked at the Berhorst Clin ic in Guatemala in 1978 (before there was global health)numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving.Try to take a break; have a good glass of Claret on me.HCB----- Original Message -----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)>Sent : Wedne sday , February 05 , 2020 5:31 AMTo: How ard Bauchner <How ard.Bauchner@jamanetwork.org>Cc: Conrad , Patric ia (NIH/NIAJD) [E] (b) (6)>Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was+flawed[Warning External Email)Howard:Your outline looks fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was onevery other night and every other weekend, hut actually never left the hospital because the patients were so sick.Best,Tony----- Original Messag e-----From: Howard Bauchner <Howard .Bauchn er@jamanetwork.org>Sent: Wednesday , February 5, 2020 6:-23- A-M- ----, a-s-r,= To: Fauci, Anthon y (NIH/NIAID) [E] CbHSubject: RE: Study+claiming+new+corona virus+can+be +transmitted+by +people +without+symptoms +was+flawedLikely come up tomorrow in our discussio n - not NEJM pape r but just the concept.Outline if OK with youNIH-002140What's up in ChinaWhat's up around the worldWhat's up in USAnd then more specific questionsls this more like HIN! than MERSCan we really know mortality risk (denom inator problem).Incubation periodHow "infectious"News on treatmentQuarantine workingSound OK?You surviving - worried a bit about your workload.HCB-----Original Message- ----From: Fa uci, Anthony (NTH/NlAID) [E] (b)(6) >Sent: Wednesday, February 05, 2020 5:20 AMTo: Howard Bauchner <Howard.Bauchner @jama netwo rk.org>Subject: RE: Srudy+claimi ng+new+corona virus+can+be+transm itted+by+people +without +symptoms +was+tlawed[Warning External Emai l]The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to theDirector of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China.-----Original Message-----From: Howard Bauchner <Howard .Bauchner@jamanetvvork .org>Sent: Wednesday, February 5, 2020 6:-1-5 -A-M-- ~-= To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) >Subject: FW: Study+claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawedTonySuspect you saw this. Big problem if true - rushing to publication - leads to big mistakes.HCB-----Original Mcssage ----------- --:;;=a<, From: Redberg, Rita (b) (Sent: Wednesday , February 05, 2020 5: 13 AMNIH-002141NIH-002142To: Howard Bauchner <Howard.Bauchner @jamanetwork.org >; Phil Fontanarosa<Phil.Fontanarosa @jamanetwork.org >Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed[Warning External Email]Assume you saw, but.hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon-2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s-2Dwrong&d=Dw IF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFUZ7y8a6zr8BltW A4gtfR WytiKtFo VM&m=4xruNHFPsXovMmiMLZWiD9OzCNhiiGOKmtHhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwBnAiRXsktAbH l rM9a3j PY &e=From:Sent:To:Fauci, Anthony (NIH/ NIAIO) [E)Thu, 6 Feb 2020 03:59:46 +0000Auchincloss, Hugh (NIH/ NIAID) [C]- ---------- (b)(6) Subject: FW: touc hing base about Texas Biomedical Research Institut ePlease take care of this.From:L arry Schlesinger ----------- (b)(6) Sent: Wed nesday, February 5, 2020 8:42 AMTo: Auchincl oss, Hugh (NIH/NIAID) [E] ----------=- (b')""('= >; Fauci, Antho ny (NIH/N IAID) [E](b)(6)Subject: to uching base about Texas Biomedical Research Insti tuteHi Tony and Hugh.I know that I am writing to you at a busy time during yet another infectious diseaseoutbreak that is rapidly evolving . However, I wanted to send you a brief note to updateyou about the transformational change going on in the landscape of our free standinginstitute with its new, sharply defined goal to be the global leader in eradicatinginfectious disease threats in the world . I know that you are familiar with us.I have been leading the institute since June of 2017 and currently finishing year one of a10 year board-approved plan of growth in our scientists , educationa l programming andcampus modernization. I believe that you are aware that we house the only privateBSL4. We also just opened our newest of 5 BSL3 facilities , this newest one being nearly8000 sq. ft. with capacity for ~100 NHPs, small animals, a complete aerosol suite and aPET CT. We also house the SNPRC, now under the leadership of Deepak Kaushal(who replaced Robert Lanford) and with the largest marmoset colony as a result ofrestructuring our building facilities (in addition to our other species . CbH4JPlease check out our newly designed website: www.txb iomed.org.The bottom line is that I left university life to lead an organiza tion that is determined tonot only discover critical, new fundamental science but also effectively and efficientlybring it full forward to create portfolios for the FDA through our business model,nimbleness, regulated science culture (GLP level), longstanding public and privatepartners through contract science ( esp. BARDA), culture and community support .NIH-002143We want to help! Please let us know if and how we can contribute to this outbreak andundoubtedly others going forward .I truly appreciate your leadership. The country gets the voice of reason on infectiousdisease outbreaks through your public efforts. I enjoyed learning more about this duringmy time on council.Best,LarryLarry Schlesinger, MDProfessorPresident and CEOTexas Biomedical Research Institute8715 W. Military Drive, San Antonio, TX 78227Email: (b)(6)Teamwork I Integrity I Diversity I Excellence I SafetyExecutive assistant:(b)(~(b) (6) Phone==== (~b)~(6~) Mobi leEmail: I- -------- (b)(6)jCONFIDENTIALITYN OTICE:T his e-mail and any files and/or attachments transmitted, may containprivileged and confidential information and is intended solely for the exclusive use of the individual orentity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that anyreview, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. Ifyou have received this e-mail in error, please immediately notify the sender stating that thistransmission was misdirected; return the e-mail to sender; destroy all paper copies and delete allelectronic copies from your system without disclosing its contents.NIH-002144From:Sent :To:Cc:Subject:Bob:Fauci, Anthony (NIH/N IAID) [E)Thu, 6 Feb 2020 03:49:36 +0000Robert KnoblerCassetti, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [ElRE: Potential Approa ch to Wuhan CoronavirusThanks for your note. It was good to bear from you. I am copying Cristina Cassetti on this e-mail. Cristinadirects the extramural coronavirus research activities. Perhaps you two can connect to discuss researchopportunities.Best,Tony-----Original Message -----From: Robert Knobler ______ "(""b')'"c"='Sent: Wednesday , February 5, 2020 10-:5-5- A-M- ---:,,:,~ To: Fauci , Anthony (NIH/N IAJD) [E] ----,----- (b)(6) > Su~ j e ct: Potential Approach to Wuhan CoronavirusDear Dr. Fauc i,You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgotyour enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984.l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, andeventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor.Lacking the correct receptor or blocking binding of the virus spike protein to the receptor with monoclonalantibodies blocked infection .On to the present problem of human coronaviruses . Vaccines will take a long time for the current crisis. Theangiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlierstudies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs aspotential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct ,there may still be sufficient untainted supplies of ARBs, such as irbesar tan, available, or production can be scaledup, if this truly is the eve of a pandemic.Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me bye-mail or my cell phone.T also did do clinical trials while with Mike, and then when I joined the neu rology faculty of Jefferson inPhi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work. Foranother time, I also have some novel ideas on how HIV become s AIDS, as well. Ironica lly, these ideas were basedupon observations I made during my analy sis ofMHV.All the Best ,Rober t L Knobler, MD, PhD(b)(6)NIH-002147From:Sent :To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Thu, 6 Feb 2020 03:28:54 +0000Cohen, ElizabethRE: treatment protocolsThe Chinese are putting together protoco ls to test certain drugs such as remdesivir.From: Cohen, Elizabeth <Elizabeth.Cohen@turner.com>Se nt: Wednesday, February 5, 2020 3:19 PMTo: Fauci, Anthony (NIH/NIAID) [E]-------=- (bc)(-=c >Subject: treatment protocolsHi Tony,We were wondering if there are any part icular protocols being suggested for treating the Wuhancoronavirus cases in the US. Are there discussions among the teams caring for these patien ts about thebest approach?Many thanks.Best,ElizabethElizabeth Cohen, MPHCNN Senior Medical CorrespondentNIH-002148From: Fauci, Anthony (NIH/NIAID) [ElSent : Thu, 6 Feb 2020 02:54:42 +0000To: Cassetti, Cristina (NIH/NIAID) [ElSubject : FW: Corona virus/sepsis treatmentAttachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc,REFERENCESC orona Virus .docxPlease handle.From : stanley satz (b)(6)Sent: Wednesday, February 5, 2020 7:20 PM ------ == To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _______ _.Subject: Corona virus/sepsis treatmentDear Dr. Fauci,(b) (4)NIH-002150Best regards,Stanley Satz, Ph.D.Chairman and Chief Scientific OfficerAdvanced Innovativ e Partners, Inc.Professor, Florida Atlantic University,Universi ty of Miami School of Medicinewww .advanced innovativepartners .comwww .bionucleo nics.com(b)(6)Confidentiality NoticeThis message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity towhich it is addressed. This communication may contain information that is proprietary, privileged or confidentialor otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized toread, print, retain, copy or disseminate this message or any part of it. If you have received this message inerror, please notify the sender immediately by e-mail and delete all copies of the message.NIH-002151(b) (4)From:Sent:To:Cc:Fauci, Anthony (NIH/NIAID) [E)Thu, 6 Feb 2020 02:54:19 +0000Conrad, Patricia (NIH/NIAID) [E)Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [ElSubject: FW: Dr. Levitt summar izes CDC 2019-nCoV Committee Report released today 5Feb 2020Attachments: M and M Wuhan Virus .pdfSee me about getting someone to prepare a response.From: Robert Levitt (b)(6bSent: Wednesday, February 5, 2020 7:50 PMTo: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) -------- (b)(6) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020Dear Secretary Azar and Dr. Fauci,I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV)epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's bestPh.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report.Below I have recorded what I think the most important facts in the report for Secretary Azarand other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying allinfected persons and their contacts . I have also added my personal thoughts on how to stopt he spread of this novel coronavirus and a persona l fear I have communicated to Secretary Azarin the past:-- President Trump signed an order preventing entry into the U.S. of any person who hastrave led to mai nland China (PRC). Exceptions in clude U.S. citizens and permanent residents andt heir famil ies. Thank you Mr. Trump.-- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r ealt ime'.-- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s.The number of ports and especia lly airports needs to be increased. The Report states that14,000 Chinese enter the U.S. daily. If the 5 airports receive 85% of these Chinese, then 2,100Chinese enter the U.S. daily at other airports without enhanced screening.-- CDC has developed its own RT-PCR test to detect 2019-nCoV in respiratory specimens. I have readcase reports where state laboratories have required too much proof of suspected Wuhan virus fromclinicians before perfo rming RT-PCR testing of specimens. CDC should provide their improved RT-PCRtest to all states and HHS should insure that all states have sufficient equipment and trainedpersonnel for rapid turn-around time.NIH-002152NIH-002153-- CDC has grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus toresearchers with verified credentials and vetting in a safe and monitored procedure.-- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in aseparate room with a N95 face mask so that they are not in range of other patients. HCWshould wear personal protection: gloves, gown, face shield or N95 mask and goggles.-- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S.CDC is doing a terrific job in getting the message out to clinicians and the public.Sent from OutlookFrom:Sent:To:Cc:Subject:Tak:Fauci, Anthony (NIH/NIAIO) [E)Thu, 6 Feb 2020 00:56:18 +0000Mak, TakCassetti, Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E]RE: An IdeaThanks for the note . It likely will be more efficient if I refer you to the programpeople in my Institute who could go over these data with you and then get meinvolved later . The reason that is tha t I am doing 18 hours pe day (seriously) aspart of the White House Task Force and it would very difficult for me to fit in ameeting to go over data. I have copied Dr. Cristina Cassetti who runs ourcoronavirus extramural research program . I will ask her by this e-mail to contactyou to have our people discuss your work with you.Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone Cb()6 )FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Mak, Tak (b)(6)Sent : Wednesday, February 5, 2020- -7:-30- -P-M- =-,--=, To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)(6) Subject: An IdeaDear Tony,It has been a while since we discussed science.NIH-002155(b) (4)(b) (4)Best regards, TakThis e-mail may contain confidential and/or privileged informat ion for the sole use of the intendedrecipient.Any review or distribution by anyone other than the person for whom it was originally intended isstrictly prohibited.If you have received this e-mai l in error, please contact the sender and delete all copies.(b)(4)Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization.If you feel you have received an email from UHN of a commercial nature and would like to be removedfrom the sender's mailing list please do one of the following :(1) Follow any unsubscribe process the sender has included in their email(2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in thesubject line. If you require additional information please go to our UHN Newsletters and Mailing Listspage.Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists.NIH-002156From:Sent:To:Cc:Subject :Jeremy:Fauci, Anthony (NIH/NIAIO) [E)Thu, 6 Feb 2020 00:00:36 +0000Jeremy Farrar;Collins, Francis (NIH/OD) [ElJosie Golding;Tabak, Lawrence (NIH/OD) [ElRE: Prevalence of infect ion and stage of the epidemic in WuhanI left out an important name for the coronavirus evolution working group.Please include her: Pardis Sabeti at the Broad Institute of MIT and HarvardThanks,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520Nation al Institutes of HealthBethesda , MD 20892 -2520Phone: (b)(6)FAX : (301 496-4409E-mail Cb()6 )The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Fauci, Anthony (NIH/NIAID) [E]Sent: Wednesday, February 5, 2020 5:25 PMTo: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] ------- (b)(6)Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E](b)(6)Subject: RE: Prevalence of infection and stage of the epidemic in WuhanJeremy:Thanks for the note. Looks like things are moving along with WHO. I will list below anumber of names for potential members of the working group to examine the evolutionary originof the 2019-nCoV in addition to the individuals who were on the call with us last Saturday:Harold Vannus - Weill Cornell Medical Center - New York CityFeng Zhang - MIT (CRISPR expe11)Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhanstrain vs other bat viruses and the SARS virus)NIH-002157Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knowsmore about hepadnaviru ses but an outstanding clinical and basic viro logist)John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over thealleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic ML V)Eugene Koonin - NCBI/National Libreary of Medicine , NIH;ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/)Wayne Hendrickson - Columbia University and the New York Structura l Biology CenterGary Nabel - Sano:fi (Boston)Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Jeremy Farrar (b)(6)Sent: Wednesday, February 5, 2020 6:21 AMTo: Fauci, Anthony (NIH/NIAID) [E] -------= (b-):(--6=)=; Collins, Francis (NIH/OD) [E](b)(6)>Cc: Josie Golding (b)(6)Subject: Re: Prevalence of infection and stage of the epidemic in WuhanFrancis and TonyCouple of things:• I spoke again with WHO this morning. I believe they have listened and acted. Let me know ifyou agreeo At the WHO meeting next week they will set up the Group who will "look at the originsand evolution of 2019n-CoV"o They have asked for names to sit on that Group - please do send any namesNIH-002158o We can have a call this week with a core group of that to frame the work of the Groupinclud ing - if you could join?o I think this puts it under the umbrella of WHO, with action this week and into nexto With names to be put forward into the Group from us and pressure on this group fromyour and our teams next week.• The team will update the draft today and I will forward immediate ly -they will add furthercomments on the glycansDoes that sound reasonable to you?JeremyFrom: "Fauci, Anthony (NIH/NIAID) [E]" ---------(b)(6)Date : Tuesday, 4 February 2020 at 13:18To: Francis Collins CbH6)>, Jeremy Farrar ----------- (b)(6) Subject: RE: Prevalence of infect ion and stage of the epidemic in Wuhan?7Anthony S. Fauci , MDDirector(b) (4)National Institute of Allergy and Infectious DiseasesBu ilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail (b)(6) ______.. _The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Collins, Francis (NIH/OD) [E] (b)(6)Sent : Tuesday, February 4, 2020 6:12 AMTo: Jeremy Farrar (b)(6)Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: RE: Prevalence of infection and stage of the epidemic in WuhanYes, --------------------------------- (b) (4)FrancisNIH-002159From: Jeremy Farrar (b)(6)Sent: Tuesday, February 4, 2020 6:08 AM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>Subject: Re: Prevalence of infection and stage of the epidemic in WuhanOn 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El ------- (bH > wrote:Very thoughtful analysis. (b)(4)FrancisFrom: Jeremy Farrar (b)(6)Sent: Tuesday, February 4, 2020 2:0-1- A-M- ----=-<-= To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>; Collins, Francis (NIH/OD) [E)(b)(6)Subject : FW: Prevalence of infection and stage of the epidemic in WuhanPlease treat in confidence - a very rough first draft from Eddie and team - they will sendon the edited , cleaner version later .Pushing WHO again todayFrom: Edward Holmes (b)(6J>Date: Tuesday, 4 February 2020 at 06 :33To: Jeremy Farrar (b)(6J>Subject: Re: Prevalence of infection and stage of the epidemic in WuhanHere's our summary so far . Will be edited further.It's fundamental science and completely neutral as written. Did not mention otheranomalies as this will make us look like loons. As it stands it is excellent basic science Ithink, which is a service in itself.NIH-002160(b) (4)(b) (4)Will finish as soon as we can.PROFESSOR EDWARD C. HOLMES FAA FRSARC Australian Laureate FellowTHE UNIVERSITY OF SYDNEYMarie Bashir Institute for Infectious Diseases & Biosecurity,School of Life & Environmental Sciences and School of Medical Sciences,The University of Sydney I Sydney I NSW 120061 Australia(b)(6)(b)(NIH-002161From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Wed, 5 Feb 2020 20:52:29 +0000Conrad, Patricia (NIH/NIAID) [E)FW: note to Patty -- and Tony FauciLet us discuss. Steve is a good guy, but I do not want to kill myse lf trying to dotoo many thingsdat the same time .Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail Cb) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Conrad, Patricia (NIH/NIAID) [E] ---------(b)(6)> Sent: Wednesday, February 5, 2020 3:27 PMTo: NIAID OD AM <NIAIDODAM@niaid.nih.gov>Subject: FW: note to Patty-- and Tony FauciPatricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520- Room 7A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaime r:The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive information. It shOuld not be usedby anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete itNIH-002164from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not acceptliability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives.From: Steve Clemons <sclemons@t hehill .com>Sent : Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)_- _-_-_-_-__-_-_-_-__-_-_-_-_- ---~= C_Hb_6)Subject : note to Patty -- and Tony FauciGreetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on ourpreparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one morerequest to your pile to think about.. .. and I am trying to see if what I am suggesting might work rightbefore your Aspen talk next Tuesday at noon.In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al JazeeraEnglish that runs four times a week on thei r global network and is garnering between 100k-200k views aweek on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of threeexperts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator onwhat we should do not only on the coronavirus but in general on the infrastructure of pandemicpreparedness in the country -- sort of a shorter form of that great PBS show you did called InvisibleKillers.We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t goover), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you haveto be at Aspen at noon {I was invited too) -- so I could take you if you like.I realize that this may be too much. -- but in these times, I think it's important to get smart commentaryand analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to themillions you are already reaching. The producers are also able to provide car and driver (b)( 4)(b) (4)Hope this might work my frie nd. I may send a short form of this to your cell phone.Call me if you want to chat, either of you, ata II best, STEVETheHlll.comSteve ClemonsEditor at Large, The Hill1625 K Street NW, Suite 900Washington, DC 20006Tel: .,.1.202.628.8500Cell: (6)Email: SClemons@TheHill.comFollow me on Twitter @SCClemons-----(b) (6).NIH-002165From:Sent:To:(b)(6)Wed, 5 Feb 2020 10:33:15 -0500Conrad, Patricia (NIH/NIAID) [E]Subject: Fwd: NTV Broadcasting Interview RequestFYIBegin forwarded message:From: Cecpep6eKOXBa ,1Kl)u-MypaTK apaxaHOBH<qH Seferbekov@ntv.ru>Date: Fehmary 5, 2020 at I 0:21: 15 AM EST -------~= To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6>lSubject: NTV Broadcasting Interview RequestMr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcastingcompany .We would like to film a brief interview with you about coronavirus, and different hypothesesabout its appearance. We want to solve the problem with mass disinformation about thisvirus, and need a professional opinion.Will it be possible to do th is at 6th , or 7th of February?Best regards,Seferbekov MuratNTV Broadcasting CompanyNIH-002170From :Sent :To:Fauci, Anthony (NIH/NIAI0) [E)Wed, 5 Feb 2020 14:36:13 +0000Conrad, Patricia (NIH/NIAID) [ElSubj ect : FW: Interview request by BBC ChineseAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Tsung-Hsien Lee <zach.lee@bbc.co.uk>Sent : Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El-- ----------"-"=-"-"-(b")(6-) :-= Subject: Interview request by BBC ChineseDear Dr Anthony s Fauci,This is Zachary from BBC Chinese.I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirusin different countries .Most of the countries told the public where the people evacuated from Wuhan reside for quara ntineand some drew local's protests . They expressed concern over close vicin ity and some even went toprotest in these places.Others like Taiwan, the authority decided to keep the quarantine location confidential. The reason is toavoid unnecessary worr isome and let people rest wel l.I would like to have an interview with you by e-mail or Skype phone with you to give some insights orcomments on this issue.If you could be quoted, the questions are as below1. Why does the government tell the public the quarantine location? Is it necessary? Or why not?NIH-002171NIH-0021722. Many residents protested because they don't want the quarantine Center for Coronavirus in theirneighborhood . Do they need to worry about it?3. What is your suggestion regarding the location of quarantine those people from Wuhan. And wh atis essenti al for Quarantin e Center for Coronaviru s?Thank you very much for your time .Zachary LeeBBC ChineseFrom:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 1 Mar 2020 01:17:02 +0000Harper, Jill (NIH/N IAID) [E]Subject: RE: Approps TA: DOE Reimbu rsement for Coronavirus Super ComputingAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)(b) (5)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6)Sent: Saturday, February 29, 2020 9:43 AM To: Fauci, Anthony (NIH/NIAID) [E]-" -"-:-"-:-====-(=b=)(=6=J>- ~-~~ Cc: Haskins, Me linda {NIH/NIAID) [E]- --------- (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronavirus Super ComputingTony,Thanks,JillFrom: "Harper, Jill (NIH/NIAID) [E)" --------- (b)(6) Date: Friday, February 28, 2020 at 5:33:38 PMNIH-001137(b) (5)To: "Fauci, Anthony (NIH/NIA ID) [El" _______(b ) (6_).>Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super ComputingTony, I will call you about this in a minuteFrom: "Haskins, Melinda (NIH/NIAID) [E]" (b)(6)Date : Friday, February 28, 2020 at 5:24:43 PM -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)>Cc: "NIAID OCGR Leg" <NIAIDOCGRLeg@mail.nih.gov>, "La Montagne, Karen (NIH/OD) [El"(b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~=S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)"-------- CbH6)",S hapiro, Neil (NIH/OD) [El" CbH Subject : Re: Approps TA: (b)(S)Sent from my iPhoneOn Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El ----------(b)( > wrote:Hi Melinda,Would you let me know what you all think of this language?Thanks.MMFrom: Friedel, Laura (Appropriations) ------------ (b)( > Sent: Friday, February 28, 2020 5:13 PM -------~= To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle(NIH/OD) (E] (b)(6)Subject: RE: DOE Reimbursement for Coronavirus Super ComputingAny progress on this Michelle? Here is language that I'm thinking of.For an additional amount for "National Institute of Allergy and InfectiousDiseases", to prevent, prepare for, and respond to SARS-CoV-2, a virus sb·ainmutat ing therefrom ("coronavirus"), or other emerging or reemerging infect iousdisease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lableNIH-001138(b) (5)until September 30, 2024: [Provided. That up to $99.500.000 of such amounts maybe tran sferred to the Depai1rnent of Energy to provide sup po1t and access toscient ific user fac ilities , includin g equ ipm ent, ena bling techn olog ies, and personne lassocia ted with the opernt ions of those scienti fic user fac ilities:]Laura FriedelMajority ClerkCommittee on AppropriationsSubcommittee on Labor, HHS and Education136 Dirksen Senate Office BuildingWashington, DC 20510(b)(6)From: Friedel, Laura (Appropriations)Sent: Friday, February 28, 2020 3:13 PMTo: Haskins, Melinda (NIH/NIA ID) [E]--------=- C"Hb"'""'>; Michelle Mitchell(b)(6)Subje ct: DOE Reimbursement for Coronavirus Super ComputingHi,Dept. of Energy is looking for $99.5 million. They are concerned that NIH wil l use theirsuper computers for coronavirus (which NIH doesn't pay for) and displace payingcustomers. What is the expectation that NIH will need to use DOE super computers? Wewould include addit ional funds (please make sure TF knows I would not take his funds andgive to DOE), but this seems extremely high to me and I was trying to understand the needfrom your perspective for these super computers . Happy to jump on the phone if that iseasier, but need this as fast as you can get it to me please- within the next hour or so.Language is below . Thank you !Sec._. (a) Funds appropriated in this title may be made available torestore amounts , either directly or through reimbursement , for obligations incurredby agencies of the Department of Health and Hum an Services for the purpo sesprovided herein pr ior to the date of enactment of this Act. This subsection shall notapply to obligations incurred by the Infectious Diseases Rapid Response ReserveFund .(b) Funds appropriated in this title [may /shall] be used when [awarding /toaward] grants and cooperative agreements in fiscal yea r 2020 to reimburse State orlocal costs incurred for the purposes provided herein after January 20, 2020 , andprior to the issuance of such awards.[(c) Funds appropriated in this title shall be transferred to other federalagenc ies for costs related to medical screening for coronavirus including any costsNIH-001139incurred through a grant, coopera tive agreement, other transaction, or contract and,once transferred, may be used to reimbur se obligation s incurred for such purpo sesprior to enactme nt of this Act.]( d) U_p to $99,500,000 of the funds a ro~riated in th is title may betransferred to the Depa rtment of Energy to_provide su1;mort and access toscient ific user facilit ies, includin g e uipm ent, enabling technologies, andpersonnel associated with the o erat ions of those scientific user facilities.( e) If any funds have been reprogrammed or trans ferred from anappropriation , as described in the notific ation submitt ed by the Secretary to theCommittees on Appropr ia tions of the House of Repr ese ntatives and the Senate onFebruary 2, 2020, prior to the date of enactment of this Act, such amounts shall berepro grammed or transferred back to that appropriation within 45 days of the date ofenactment of this Act.Laura FriedelMaj ority ClerkCommittee on AppropriationsSubcommittee on Labor, HHS and Education136 Dirksen Senate Office BuildingWashington, DC 20510(b)(6)NIH-001140From: Fauci, Anthony (NIH/NIAIO) [E)Sent:To:Subject:Thu, 13 Feb 2020 22:36:17 +0000Messonnier, Nancy (CDC/DDID/NCIRD/0D)RE: NASNancy:The official USG group will be convened by NAS. Bob Kadlec is the person withdirect knowledge of that. In addition, there is an ad hoc group informally led byJeremy Farrar of Wellcome Trust. This group has about 15 people, all of whomare highly respected scientists, mostly evolutionary biologists who are conveningby e-mail and conference calls (I have been on 2 of these calls since Jeremyinvited me) to look at all of the bat, pangolin and human coronavirus sequencesto try and determine the evolutionary origin. This is not my area of expertise andso I have backed off and am leaving it all to Jeremy.Best,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >Sent : Thursday, February 13, 2020 5:28 PM ------ ..-.-,= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)>Subject: RE: NASThanks. Is someone conven ing them?From: Fauci, Anthony (NIH/NIAID) [E] ______ (b_H_6)Sent: Thursday, February 13, 2020 5:07 PMNIH-001920To: Messonnier, Nancy (CDC/0010/NCIRD/OD) ------ (b)(6)Subject: RE: NASNancy:It is not a report. It is a letter from NAS to OSTP saying that it is important tobring together a group of experts to study the evolutionary origin the COVID19. Iam attaching it here. I have no idea if it has been widely distributed and so pleasekeep it internal.Best,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone Cb()6 )FAX: (301 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) ------- (b)(6) Sent: Thursda y, February 13, 2020 1:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)(6) Subject: NASEither you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2.Thanks.NancyNIH-001921--From:Sent:To:Subject:Attachments:Nancy:Fauci, Anthony (NIH/NIAIO) [E)Thu, 13 Feb 2020 22:06:37 +0000Messonnier, Nancy (CDC/DDID/NCIRD/OD)RE: NASNASEM Response to OSTP re Coronavirus_February 6 2020.pdfIt is not a report. It is a letter from NAS to OSTP saying that it is important tobring together a group of experts to study the evolutionary origin the COVID19. Iam attaching it here. I have no idea if it has been widely distributed and so pleasekeep it internal.Best,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Messonnier, Nancy (CDC/0010/NCIRD/OD) CbH >Sent: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] CbH6)>Subject: NASEither you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2.Thanks.NancyNIH-001922--From: Fauci, Anthony (NIH/NIAIO) [E)Sent: Thu, 6 Feb 202015:21:22 +0000To: Billet, Courtney (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer(NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E]Subject: RE: Redfield/Fauci nCoV op-edAttachments: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docxHere it is.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It shou ld not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [E] (b)(6)Sent : Wednesday, February 5, 2020- -3:-43- -PM- ::;..,..-,= To: Fauci, Anthony (NIH/NIAID) [E] ~=======-~= Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E)(b)(6J>; Routh, Jennifer (NIH/NIAID) [E) --------- (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)>Subject: FW: Redfield/Fauci nCoV op-edHere is the op-ed as cleared by WH.Any issues with this?(b) (5)From: Brennan, Patrick (OS/ASPA)Sent : Wednesday, February 5, 2020 3:39 PM(b)(6)-------~~ To: Routh,Jennifer (NIH/NIAID) [E]- -------- (b)(6); Lepore, Loretta (CDC/0D/OCS) (b )( 6)Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC)(b)(6J>; Bonds, Michelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID)':["E:::)-====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan,Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6);NIH-002108Stecker, Judy ( OS/IOS) CbH6J; Murphy, Ryan (OS/ ASPA) CbH6JPratt , Michael (OS/ASPA) (b)(6)0akley, Caitlin 8. (OS/ASPA)(b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] ========,~';5""=-- (b )( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID)~[E~l =====~ (b~)(=6)Subject: RE: Redfield/Fauci nCoV op-edAttached is a tracked changes version and a clean version of what cleared the WH - they had a fewsentences they would like to be added (wh ich, in the tracekd changes version, I have added commentsto explain who suggested it and in some cases why), but almost all of these edits are non-substantive.Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all aregood to pitch this as you wish - (b) (5)From: Routh, Jenn ifer (NIH/NIAID) [E] (b)(6)Sent : Sunday, February 2, 2020 6:11 -P-M-~ ~ To : Lepore, Loretta (CDC/OD/OCS) <j (b)( ~ >Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC)------(b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet,Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS)CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>S; tecker, Judy (OS/IOS) :::======~=-'- -c-c= --~--~====(b):(6:)>:;! M,_ur.p:hy,,_ R_y_an~ (O~S/A SPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill(HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John(NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6)Subject: RE: Redfield/Fauci nCoV op-edAll - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci.Thanks,JenJennifer Routh [E]News and Science Writing BranchOffice of Communi cations and Government Rela tionsNational Institute of Allergy and Infectio us Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda, MD 20892Direct: Cb()Disc laimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not beused by anyone who is not the original intended recipient. If you have rece ived th is e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. The National Institute or Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives.From: Lepore, Loretta (CDC/OD/OCS) ____ C_>b_C_6 )Sent : Sunday, February 2, 2020 2:39 PMNIH-002109To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds,Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Courtney (NIH/NIAID} [ElCc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S};Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA};Myles, Renate (NIH/OD} [E]Subject : RE: Redfield/Fauci nCoV op-edGood afternoon all,I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ourcolleagues at NIH.Please reach out with any quest ions.Best,LorettaFrom: Fine, Amanda (NIH/OD) [El- ------- (b)(6) Sent: Friday, January 31, 2020 6:36- P-M- --,.= To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA}(b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia"(:N""::l"'H.'"/"'::N''":'.I"A~'.l"-D:-}:-:[~E:]-::::::===-,:_-~ (;ba~=-c,-6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>;Lepore, Loretta (CDC/00/0CS} (b)(6)>Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS)(b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b")"('=6); Murphy, Ryan (OS/ASPA}(b)(6); Pratt, Michael (OS/ASPA} (b)(6); Oakley, Caitl in 8.7( 0:-S::/- :-A:-S:-P::A-:--}: --.======;...._--= (b")' "("6")">'; Hall, BiI I ( HHS/A SPA} (b) (6)>; Myles, Renate _____ _,,(NIH/OD) [E] ______ C_>bC6)Subject: RE: Redfie ld/Fauci nCoV op-ed+ Renate Myles for awarenessFrom: Galatas, Kate (CDC/OD/OADC} ------ (b)(6) Sent : Friday, January 31, 2020 6:34 PM ------~~ To: Brennan, Patrick (OS/ASPA} (b)(6) 1>; Bonds, Michelle E. (CDC/0D/OADC)(b)(6); Fine, Amanda "(:'~N:I-H::-/-O:~- D:}- :[:E:--] :--:=====...:....__, (ab~-~,<-6)>;C onrad, Patricia (NIH/N IAID) [E]=====:=;..--=- (b.),(.:=6, )>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1>; Lepore, Loretta (CDC/00/0CS} (b)(6)Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS),..:..!::====::::::_:_~(b)(6)>; Stecker, Judy (OS/10S} (b)(6); Murphy, Ryan (OS/ASPA}(b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B.(05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6)Subject: Re: Redfield/Fauc i nCoV op-edHi, Patrick -We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH commscan move thru with thei r editing/revisions.NIH-002110let me know if that sounds OK. We will likely not have a cleared version out of CDC until late Saturdayat the earliest.Take care,KateGet Out look for iOSFrom: Brennan, Patrick (OS/ASPA) (b)(6)Sent : Friday, January 31, 2020 5:31:46 PMTo: Bonds, Michelle E. (CDC/0D/OADC)_ ___ (~b)- (6=) >; Fine, Amanda (NIH/OD) [El(b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet, Courtney(NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)>Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS)(b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA)(b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B.":"::":--:-'.:-:-::--:-:-::=====::....-~~(OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate(CDC/OD/OADC) (b)( >Subject : Redfield/Fauci nCoV op-edCDC and NIH folks,Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding thereasons/thinking behind the policy announced today. I assume the right building blocks for it would bethe remarks they made today- which I believe you all should have the copy/notes for? I have theSecretary's, which we'll be sending around/post ing shortly and I'll make sure to re-up it here so you allhave it.It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!)Please let me know how I can help wi th t his.Best,PatrickPatrick BrennanDirector of SpeechwritingDepartmen t of Health and Hum an ServicesOffice: (b) (6) I Cell (b) (Predecisional/deliberative communicationNIH-002111From:Sent :To :Subj ect :FYIAnthony S. Fauci, MDDirecto rFauci, Anthony (NIH/NIAI0) [E)Tue, 11 Feb 2020 12:54:11 +0000(b)(6)FW: Following Up If We can Be of Any AssistanceNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: Cb) (6)FAX: (301 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Kadlec, Robert (OS/ASPR/1O) --------- (b)( >Sent: Tuesday, February 11, 2020 7:28 AMTo: CbHCc: (b)(6) Elvander, Erika (OS/OGA) CbH6); Lamana,Joseph (OS/ASPR/E_M_ MO..). ;_-=====~:;;;---:------:----:-----:---:-- Cb)( ; Disbrow, Gary;(.O.S./. A._S..P .R :/ B;.__A..R_ .D A.). :.!:=~"""'.'.'"-~Cb-H.6-); -Y.e-s-k-ey, Kevin (OS/ASPR/1O) ---------(b)( >; Fauci, Anthony (NIH/NIAID) [E] ---------(b)(6) Subject: RE: Following Up If We can Be of Any AssistanceDear Dr. Suzuki we heard from Jun the news that your Prime Minister gave app roval fo r t hedeplo ym ent of our team. We are moving expediti ous ly to get them th ere to assist. In light ofthe situ at ion and t he increasing numbers of cases on the ship, CbH5>NIH-001970(b) (5)Again, we are grateful and excited that we have the opportunity to work together.Kan pailBobFrom: Kadlec, Robert /OS/ ASPR/10)Sent: Monday, February 10, 2020 8:14 PMTo: (b)(6)Cc: (b)(6); Elvander, Erika (OS/OGA)_ .......=====::"C"b"H6"); '~La~m:a-n-a, Joseph (HHS/ASPR/OEM) Cb)(6)(b)(6)Subject: Following Up If We can Be of Any AssistanceDear Dr. Suzuki -I hope this finds you I good health and expect that you are deeply involved in the events ofcoronavirus in your region . I understand from various communications with the MHLW that isconsidering ending the quarantine early and releasing passengers from the Diamond Princess,especially those who are 80 years of age or older. Given the media reports and publicperception there is pressure to do th is. However, as medical experts, you and I both know thatdays 3 - 8 are within the norma l incubation period and these new positives do not likelyrepresent shipboard transmission. As such, HHS is willing to coordinate U.S. medical expertswho can engage with English language media explaining and reassuring the passengers, crew,and public.Regarding support for the quarant ine, ASPR is ready to deploy a team of 3-5 people quickly, andas many 12 people to Japan to support as suggested in the previous call. If we can assist youand your team in managing the Americans currently in quarantine please let me know. If thereis other support do let me know and ASPR will work to assist. As we've talked for the past 18months about such a scenario, this may not be the one we envisioned, but it is a perfect case aswe can clearly ident ify the Americans, they are in a contained area. Our mutual efforts andplanning have paid unexpected dividends.I am available to discuss via teleconference at your convenience. I am grateful fo r all MHLWhas done to support this complicated response on top of your work supporting repatriation anddomestic monitoring of your own citizens. We are grateful for Dr. Sugihara's herculeaninformation sharing efforts and the rest of your MHLW team support during this event; itNIH-001971NIH-001972validates of the importance of our ongoing liaison program and the long term benefits of ourmutual commitment to each other's public health securityPlease remain well and I look forward to see you again soon.Best wishes and warm regards.Dr Bob KadlecASPRFrom:Sent:To:Fauci, Anthony (NIH/NIAID) [E]Mon, 10 Feb 2020 18:43:59 +0000Brennan, Patrick (OS/ASPA)Cc:Subject:Hall, Bill (HHS/ASPA);Conrad, Patricia (NIH/NIAID) [E]RE: Draft of emailAttachments: 2 10 20 email - with Fauci edits.docxHere is the document with my tracked changes. GAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Brennan, Patrick (OS/ ASPA) ---------- (b)(6)Sent: Monday, February 10, 2020 1:26 PM --------=-c-= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >Cc: Hall, Bill (HHS/ASPA) <Bill.Hall@HHS.GOV>Subject: Draft of emailDr. Fauci - below and in the attached is our proposed draft response, and then Cuccinelli'semail text below for context. We're waiting on a potential detail/point or two from ASPR thatmay help flesh it out a bit but we'll see if we actually need it. Thank you !<< File: 2 10 20 email.docx >>Draft HHS responseFellow task for ce members,Thanks for your message, Ken, and I look fo rw ard to ou r di scussion tod ay.NIH-001994(b) (5)Looking forward to discussing more later today.KenTo mv fellow task force members(b) (5)NIH-001995(b) (5)NIH-001996I look forward to speaking with you all again this afternoon.Patrick BrennanDirector of Speechwrit ingDepartment of Health and Human ServicesOff ice: (b)(6) I Cell: (b)(6)NIH-001997From:Sent :To:Subject:Anthony S. Fauci , MDDirectorFauci, Anthony (NIH/NIAIO) [ElSun, 9 Feb 2020 23:54:27 +0000(b)(6)FW: WHO advance team on coronavirus on way to China - Tedros tweetNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Grigsby, Garrett (HHS/OS/OGA)Sent : Sunday, February 9, 2020 6:35 PM(b) (6)•>To: Fauci, Anthony (NIH/NIAID) [El --------------=---:-=(b:)-(i ; Harrison, Brian (HHS/10S) (b )( 6)Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA)"':'-"--:----:-(:b):( =·>=; Z=eb=ley~, K yle (HHS/0S/OGA) ".-:======(b=)(6)~ R=ed field, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)((FDA/OC) --------- (b)(6)>; Bright, Rick (OS/ASPR/BARDA) --------- Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweetDr F,From: Fauci, Anthony (NIH/N IAID) [E] -------- (b) ~ > Sent: Sunday, February 9, 2020 6:24 PMTo: Grigsby, Garrett (HHS/OS/OGA)------- .C-..Hb..,=6)>; Harrison, Brian (HHS/105)(b)(6j>NIH-0020 14(b) (5)Cc: Kerr, Lawrence ( HHS/0S/OGA) Cb() >; Elvander, Erika (OS/OGA)(b)(6); Zebley, Kyle (HHS/0S/OGA)"(:C -::-D:~C:/"0':::""D.::":)';:=' ==='c (b~)(~ >; Kadlec, Robert (O S/A SPR/I0)~======C~b~C) >; Redfield, Robert R. (b)(6)>; Abram , Anna( FDA/OC)- -------- (b)( 6)>; Bright, Rick ( OS/A SPR/BARDA) -------- (b)(6) Subjec t: RE; WHO advance team on coronavirus on way to China - Tedros tweetAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail : (b)(6)(b) (5)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Grigsby, Garrett (HHS/0S/OGA)Sent : Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6)(b)(6)--:-::.::=========!~=Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6; JElvander, Erika (OS/OGA)(b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>R;e dfield, Robert R.( C~D:-C:-/:0-:::-D:-:):: -:.===== (=b)s,:(:6~; ); Fauci, Anthony ( NIH /N IAID) 7[ E::]---.:::=====~ (b~)(=6)>; KadI e c, Robert(OS/ASPR/10) (b)(6)>; Abram, Anna (FDA/OC) (b)(6)>; Bright,Rick (OS/A SPR"/"-B:AR_D_A~)--======~ (=b)-(~6)Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweetBrian - more clarity from "the horse's mouth" on this advance trip ... see below .From: Grigsby, Garrett (HHS/OS/OGA)Sent : Sunday, February 9, 2020 6:01 PM --------=-cc-c= To: SCHWARTLANDERB, ernhard F. (b)(6)Cc: SIMONSON, Stewart (b)(6)>Subject : RE: WHO advance team on coronavirus on way to China - Tedros tweetMany thanks, Bernard! I know I'll be asked, so I will pass your email up thechain ...NIH-0020 15Take care and thanks again!From: SCHWARTLANDERB, ernhard F.- --------- (b)(6)Sent: Sunday, February 9, 2020 5:59 PMTo: Grigsby, Garrett (HHS/OS/OGA)------- -= (b=H=6)>Cc: SIMONSON, Stewart (b) (6)Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweetHi Garrett,We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizingthe TOR and composition of the joint WHO - China mission. As you are much aware, the US has given usa number of names who will be able and wi lling to jo in such a mission. We have received similarproposals from other countries and will now match the "long list" of experts with the required specificexpertise.We are hoping to have more clarity over the coming days and will obviously keep you in the loop. Theoverall number will be kept at a level to make sure that the team is fully operational.With my warmest wishesBernhardDr Bernhard SchwartlanderChef de CabinetWorld Health OrganizationOn 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA)wrote:Bernard,Hope you had a good weekend.(b) (6)> ---------I'm reaching out to get more clarity on the WHO experts team issue -please see article below . I've heard everything from an advance groupof one or two individuals to 15 people discussed in the article. I haven'theard any word about US people, and I was just with Dr Redfield latethis afternoon and he was in the dark too.NIH-002016Any additional information wil l be deeply appreciated.Thanks!From: Kerr, Lawrence (HHS/OS/OGA) (b)( >Sent: Sunday, February 9, 2020 5:03 PM -------- == To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle(HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA)----------(b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweetFebruary 9, 2020 / 4:01 PM/ Updated an hour agoUPDATE 1-WHO advance team oncoronavirus on way to China - TedrostweetStephanie NebehayBy Stephanie NebehayGENEVA, Feb 9 (Reuters)• An advance team of international experts led by the WorldHealth Organization (WHO) has left for Beijing to help invest igate China's coronav irusepidemic, the Geneva-based agency said on Sunday.WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing for talkswith President Xi Jinping and Chinese ministers in late January, returned with anagreement on sending an international mission.But it has taken nearly two weeks to get the government 's green light on its composition,which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, aCanadian epidemiologist and emergencies expert, was heading it."I've just been at the airport seeing off members of an advance team for the @WHO-led#2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran ofpast public health emergencies," Tedros said in a tweet from Geneva.Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with topChinese health officials, told Reuters last week that they were discussing a list of expertswith China."Because it is a joint mission, they need to be on board, it's not just an international groupgoing there. We have about 15 people," said Briand, director of Global Infectious HazardPreparedness at WHO.China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing thenumber killed globally by the SARS epidemic, as authorities made plans for millions ofpeople returning to work after an extended Lunar New Year break.The virus , which has spread to two dozen countries, has killed some 2% of more than37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show.The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinesecentral government imposed a lockdown on 60 million people in Hubei province and itscapital Wuhan, epicentre of the virus that emerged in December in a seafood marke t.NIH-002017NIH-002018Tedros said on Saturday that he hoped the team would include experts from the U.S.Centers for Disease Control (CDC)."It has to be meaningful on the ground," Lawrence Gostin, professor of global health law atGeorgetown Law, said in an interview in Geneva this week.Gostin called for a "genuine partnership with transparent flows of information andaccountability for the response", adding that there should be a strong CDC presence."CDC has got no peer in terms of its experience and technical expertise in dealing withinternational outbreaks," he said."But the other benefit is the smart diplomacy, what it could signal is that despite all of ourdifferences in ideology, trade , politics, that when faced with a common threat to humanity,we come together as a human community to tackle it," Gostin said.Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten DonovanOur Standards:The Thomson Reuters Trust Prin cip les.From: Fauci, Anthony (NIH/NIAID) [E)Sent : Fri, 7 Feb 2020 03:55:22 +0000To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence{NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [ElCc: Shaya, Cecile (NIH/OD) [ElSubject: RE: Coronavirus - HHS Supplemental Table - Close Hold(b) (5)From: Shapiro, Neil {NIH/OD) [El (b)(6)Sen t: Thursday, February 6, 2020 8:08 PM -----~ = To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El(b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne"":"----:----:-:-:-::-====::!.....:.--~~(NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6)Cc: Shaya, Cecile (NIH/OD) [El (b)(6)Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold(b) (5)NeilFrom: Collins, Francis (NIH/OD) [El (b)(6)Se nt: Thursday, February 6, 2020 4:59 PMTo: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {NIH/OD) [El(b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne"":"----:-:-:-:-:-:-::.:====:::::..;,-- ~=(NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6)Cc: Shaya, Cecile (NIH/OD) [El (b)(6)>Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold(b)(S)FCFrom: Shapiro, Neil {NIH/OD) [E] ------- (b)(6)>Sent: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El ------- (b-)(-6-);- -T-a=ba k, Lawrence {NIH/OD) [E](b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~(NIH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc:Shaya,Ce .c..:i l-e:-- (:-N:~-IH~/:0---0::::7-) ':["-E:-:l ::=-.===--..;_ ("b")-'(:6--)= -Subject : FW: Coronavirus - HHS Supplemental Table - Close HoldImpo rt ance: HighNIH-002087ASFR provided the pdf attachment and the explanation below. They emphasized on the phone too thatthis is very close hold . Cb) (5i(b) (5)NeilFrom: Cabezas, Miriam (HHS/ASFR) ----------- Sent: Thursday, February 6, 2020 2:32 PM ----~~ To: Kelly, Alison (CDC/OCOO/OFR/OA) (b)(6)>; Berger, Sherri (CDC/OCOO/O0)CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>S; haya, Cecile (NIH/OD) [E] =====~ Cb~>; Peti llo, Jay (OS/ASP':R"'/ 7M-:-F::H--::-C-~:) -====~ CbH6J>D;u bay, Johanna( OS/ ASPR/M FHC) (b)(6)Cc: Goyle, Suraj (OS/ASFR) (b)(6)>; Falisi, Angela (OS/ASFR)White, RaeShawn (OS/ASFR) CbH6J>C;o rmier, Justin (HHS/ASFR)(b) ( >Subject: Coronavirus - HHS Supplemental Table - Close HoldInformation in this email is close hold.Good afternoon -(b) (6)>;Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. Wewant to make sure you have awareness of the activities that are identified across these three agencies.Let us know if you have any questions . This information should not be shared broadly.MiriamNIH-002088From: Fauci, Anthony (NIH/NIAIO) [ElSent : Fri, 7 Feb 2020 03:38:07 +0000To: Marston, Hilary (NIH/NIAID) [E]Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - MinisterMa of China Response Letter - 00430215Please take care of this on my behalf. Thanks.From: Marston , Hilary (NIH/NIAID) [E] (b)(6)Se nt: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E]< (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert{NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >;McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E]------- CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGR Correspondence <NIAIDOCGRCorrespondence@mail.nih.gov>; Gilles, Sharon(NIH/NIAID) [E) (b)(6) Fauci, Anthony (NIH/N IAID) [E) (b)(6);Conrad, Patricia (NIH/NIAID) [E) (b)( >Subject : RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of ChinaResponse Letter - 00430215From: Harris, Kara (NIH/NIAID) [El CbH6)>Sen t: Thursday, February 6, 2020 3:00 PMTo: Handley, Gray (NIH/NIAID) [E]---------=- (b")"("=6) Marston, Hilary (NIH/NIAID) [El(b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert(NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)(McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El--------- (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGR Correspondence <NIAIDOCGRCorrespondence@mail.nih.gov>; Gilles, Sharon(NIH/NIAID) [E] (b)(6)NIH-002093(b) (5)Subject: FW: ** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of ChinaResponse Letter - 00430215Importance: HighAll-Please see the note below from Exec Sec. Please provide any comments to NIAID OCGRCorrespondence by 3:30 p.m. Please note - Exec Sec is looking for show-stopping comments only.Thank you,KaraFrom: Malliou, Ekaterini (OS/10S) ---------- (b)(6)> Sent: Thursday, February 6, 2020 2:25 PM ---------=-c-=, To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS)(b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC)--~-.-:::====:!(.b-)(6-) Chan..g;,~; W. :il.liam {HHS/OGC) (b)(6)>; Barry, Daniel J(HHS/OGC)" ~' ~-.-:::==== (b=)(=6)::>..;: ..sh_u.y:.;,,, .B~ryan (OS/ASPR/10) (b)(6); Bird,Catherine (05/0GC) (b)(6) OS OGC-10 <Contro1Desk.OGCl0@hhs.gov>; ASPR ExecSec (OS/ASPR)< ASPRExecSec@hh.gsov>Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S)(b)(6) >; Hawk~i-ns-,-J:a- m- ar- (:-H:-H:--S:-/:0".:S")": -:.":'=.=:;.....::;._...:,__...:...~ (b:).,.(,6-=);, Horska, Katerina(HHS/IOS) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6);Zebley, Kyle (HHS/0S/OGA)- ------- (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] (b)(6)Subject : Clearance Due 6pm (2/6): **Time -Sensitive** Coronavirus - Min ister Ma of China ResponseLetter - 004302 15Please find attached for your clearance a response to Minister Ma's letter to the Secretary, and arecent conversation with him. (b) (5)Please note that the Secretary has already reviewed and edited the attached responseWe appreciate your expedited review and clearance by 6pm today, 2/6.Thank you,Kat****************************************Ekaterini (Kat) Malliou , DrPH, MPHSenior Policy Coordinator[mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices200 Independence Ave SW, Suite 619H, Washington, DC 20201, USATel: (b)(6) Cell: (b)( , Email: (b)(6)NIH-002094From:Sent :To:Cc:(b)(6)Thu, 6 Feb 2020 18:56:07 -0500Conrad, Patricia (NIH/NIAID) [E)Billet, Courtney (NIH/NIAID) [ElSubject: Re: FROM CAITLIN OAKLEY -Atlantic reporter respondedPlease schedule call for tomorrow.On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/NIAID) [E](b)(6) wrote: ----------See below -the reporter responded to Caitlyn - not Courtney- he canspeak today or tomo rrow. Do you want to call tonight or have meschedule for tomorrow?Tomorrow is quite full but can make it happen ... let me knowYes, happy to talk today or tomorrow.I'm at (b) (6)If Dr. Fauci is avai lable, that would be great.Best,Peter NicholasPatr icia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Inf ect ious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The information in this e-mail and any of its attachments is confidential and may contain sensitive information. ItNIH-002101should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in errorplease inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergyand Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and notexpress ly made on behalf of the NIAID by one of its representatives .From: Oakley, Caitlin B. (OS/ASPA) ~- --------- (b)(6)> Sent: Thursday, February 6, 2020 4:12 PM ------ ~= To: Billet, Courtney (NIH/N IAID) [El (b)( >; Conrad, Patricia (NIH/NIAID) _______ _,[El (b) (6)Subject: FW: follow up re: Coronavirus storyCaitlin B. OakleyDeputy Assis tant Secretary, Nat ional SpokespersonOffice of the Assistant Secretary for Public AffairsU.S. Department of Health and Human Services(b)(6))From: Peter Nicholas <pnicho las@t heat lant ic.com>Sent: Thursday, February 6, 2020 3:00 PM -------- -=---= To: Oakley, Caitlin B. {OS/ASPA) ----------(bH > Subject: Re: follow up re: Coronavirus storyHi,Yes, happy to talk today or tomorrow.I'm at (b)(6). If Dr. Fauci is available, that would be great.Best,PeterOn Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA)(b)(6) wrote: ----------- F o 11o wing up on this .... does today work?And I know Dr. Fauci's office is trying to get in contact as well. He's a memberof the taskforce. Can we make this happen?Caitlin B. OakleyDeputy Assistant Secretary, National SpokespersonOffice of the Assistant Secretary for Public AffairsU.S. Department of Health and Human Services(b)(6)NIH-002102From: Oakley, Caitlin B. (OS/ASPA)Sent: Wednesday , February 5, 2020 3:55 PMTo: pnicho las@theat lant ic.comCc: Hall, Bill (HHS/ASPA) ____ C_b)_(6_) >Subject: follow up re: Coronavirus storyPeter- Thanks for the chat yesterday. Have a few folks that I'd like to get you onthe phone with about your piece. Would you have time to chat with Bill Hall and Ilater today?And when is your deadline for the piece?Talk soon,Caitlin B. OakleyDeputy Assistant Secretary, Natio nal Spokesper sonOffice of the Assistant Secretary for Public AffairsU.S. Department of Health and Human Services(b)(NIH-002103From: Fauci, Anthony (NIH/NIAIO) [E)Sent: Thu, 6 Feb 202015:21:22 +0000To: Billet, Courtney (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer(NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E]Subject: RE: Redfield/Fauci nCoV op-edAttachments: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docxHere it is.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It shou ld not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [E] (b)(6)Sent : Wednesday, February 5, 2020- -3:-43- -PM- ::;..,..-,= To: Fauci, Anthony (NIH/NIAID) [E] ~=======-~= Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E)(b)(6J>; Routh, Jennifer (NIH/NIAID) [E) --------- (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)>Subject: FW: Redfield/Fauci nCoV op-edHere is the op-ed as cleared by WH.Any issues with this?(b) (5)From: Brennan, Patrick (OS/ASPA)Sent : Wednesday, February 5, 2020 3:39 PM(b)(6)-------~~ To: Routh,Jennifer (NIH/NIAID) [E]- -------- (b)(6); Lepore, Loretta (CDC/0D/OCS) (b )( 6)Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC)(b)(6J>; Bonds, Michelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID)':["E:::)-====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan,Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6);NIH-002108Stecker, Judy ( OS/IOS) CbH6J; Murphy, Ryan (OS/ ASPA) CbH6JPratt , Michael (OS/ASPA) (b)(6)0akley, Caitlin 8. (OS/ASPA)(b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] ========,~';5""=-- (b )( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID)~[E~l =====~ (b~)(=6)Subject: RE: Redfield/Fauci nCoV op-edAttached is a tracked changes version and a clean version of what cleared the WH - they had a fewsentences they would like to be added (wh ich, in the tracekd changes version, I have added commentsto explain who suggested it and in some cases why), but almost all of these edits are non-substantive.Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all aregood to pitch this as you wish - (b) (5)From: Routh, Jenn ifer (NIH/NIAID) [E] (b)(6)Sent : Sunday, February 2, 2020 6:11 -P-M-~ ~ To : Lepore, Loretta (CDC/OD/OCS) <j (b)( ~ >Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC)------(b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet,Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS)CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>S; tecker, Judy (OS/IOS) :::======~=-'- -c-c= --~--~====(b):(6:)>:;! M,_ur.p:hy,,_ R_y_an~ (O~S/A SPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill(HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John(NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6)Subject: RE: Redfield/Fauci nCoV op-edAll - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci.Thanks,JenJennifer Routh [E]News and Science Writing BranchOffice of Communi cations and Government Rela tionsNational Institute of Allergy and Infectio us Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda, MD 20892Direct: Cb()Disc laimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not beused by anyone who is not the original intended recipient. If you have rece ived th is e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. The National Institute or Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives.From: Lepore, Loretta (CDC/OD/OCS) ____ C_>b_C_6 )Sent : Sunday, February 2, 2020 2:39 PMNIH-002109To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds,Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Courtney (NIH/NIAID} [ElCc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S};Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA};Myles, Renate (NIH/OD} [E]Subject : RE: Redfield/Fauci nCoV op-edGood afternoon all,I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ourcolleagues at NIH.Please reach out with any quest ions.Best,LorettaFrom: Fine, Amanda (NIH/OD) [El- ------- (b)(6) Sent: Friday, January 31, 2020 6:36- P-M- --,.= To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA}(b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia"(:N""::l"'H.'"/"'::N''":'.I"A~'.l"-D:-}:-:[~E:]-::::::===-,:_-~ (;ba~=-c,-6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>;Lepore, Loretta (CDC/00/0CS} (b)(6)>Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS)(b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b")"('=6); Murphy, Ryan (OS/ASPA}(b)(6); Pratt, Michael (OS/ASPA} (b)(6); Oakley, Caitl in 8.7( 0:-S::/- :-A:-S:-P::A-:--}: --.======;...._--= (b")' "("6")">'; Hall, BiI I ( HHS/A SPA} (b) (6)>; Myles, Renate _____ _,,(NIH/OD) [E] ______ C_>bC6)Subject: RE: Redfie ld/Fauci nCoV op-ed+ Renate Myles for awarenessFrom: Galatas, Kate (CDC/OD/OADC} ------ (b)(6) Sent : Friday, January 31, 2020 6:34 PM ------~~ To: Brennan, Patrick (OS/ASPA} (b)(6) 1>; Bonds, Michelle E. (CDC/0D/OADC)(b)(6); Fine, Amanda "(:'~N:I-H::-/-O:~- D:}- :[:E:--] :--:=====...:....__, (ab~-~,<-6)>;C onrad, Patricia (NIH/N IAID) [E]=====:=;..--=- (b.),(.:=6, )>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1>; Lepore, Loretta (CDC/00/0CS} (b)(6)Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS),..:..!::====::::::_:_~(b)(6)>; Stecker, Judy (OS/10S} (b)(6); Murphy, Ryan (OS/ASPA}(b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B.(05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6)Subject: Re: Redfield/Fauc i nCoV op-edHi, Patrick -We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH commscan move thru with thei r editing/revisions.NIH-002110let me know if that sounds OK. We will likely not have a cleared version out of CDC until late Saturdayat the earliest.Take care,KateGet Out look for iOSFrom: Brennan, Patrick (OS/ASPA) (b)(6)Sent : Friday, January 31, 2020 5:31:46 PMTo: Bonds, Michelle E. (CDC/0D/OADC)_ ___ (~b)- (6=) >; Fine, Amanda (NIH/OD) [El(b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet, Courtney(NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)>Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS)(b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA)(b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B.":"::":--:-'.:-:-::--:-:-::=====::....-~~(OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate(CDC/OD/OADC) (b)( >Subject : Redfield/Fauci nCoV op-edCDC and NIH folks,Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding thereasons/thinking behind the policy announced today. I assume the right building blocks for it would bethe remarks they made today- which I believe you all should have the copy/notes for? I have theSecretary's, which we'll be sending around/post ing shortly and I'll make sure to re-up it here so you allhave it.It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!)Please let me know how I can help wi th t his.Best,PatrickPatrick BrennanDirector of SpeechwritingDepartmen t of Health and Hum an ServicesOffice: (b) (6) I Cell (b) (Predecisional/deliberative communicationNIH-002111From:Sent:Fauci, Anthony (NIH/NIAIO) [E)Thu, 6 Feb 2020 14:54:16 +0000To :(NIH/NIAID) [E]Cc:Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, HilaryConrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E]Subject: RE: ASF: rAzar/Pompeo op-edAtt achment s: 2 5 20 pompeo azar op-ed State - with Fauci tracked edits .. docxHere are my tr acke d ed its. Tha nks.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [El (b)(6)>Sent : Thursday, February 6, 2020 7:31 AM ------ == To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E]_______ Cb _>C6); Marston, Hilary (NIH/NIAID) [E] (b)(6)Cc: Conrad, Patricia (NIH/NIA ID) [E] CbH ; Routh, Jennifer (NIH/NIAID) [E](b)( >Subject: ASF: rAzar/Pompeo op-edSending to all of you simultaneously, in the interest of time. Our comments are due back at noon .From: "Brennan, Patrick (O5/ASPA)" (b)(6)>Date: Thursday, February 6, 2020 at 1:23:26 AMTo : "Routh, Jennifer (NIH/NIAID) [E]" ------- =(b.H...=,6)>, "Bonds, Michelle E. (CDC/OO/OADC)"(b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El" :::::======~~ (b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" --------- (b)(6)>, "Kane, EIieen (OS/ ASP R /OE A)" (b)(6J>, "Michael, Gretchen (O5/ASPR/OEA)",;___;__ _;____,:_::::==:::;(~b~~<6;-,)-,:,::B--:i:l:l:e---t:-,- -C-:o=urtney (NIH/NIA I D) [E]" (b)(6)> , "Le po re,Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)(6),"Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)"NIH-002112(b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:=(HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" ----------(b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" <ASPADeputies@hhs.gov>Subject : For review by noon Thurs: revised Azar/Pompeo op-edHi all,Attached is a largely new draft of the Azar/Pompeo op-ed tha t------------------------------- (b) (5) I've made a couple additions and edits to their new version , which I've tracked/flagged.NIAID, CDC, and OGC, please let me know if this looks OK by noon tomorrow . Thank you!Best,Pat rickNIH-002113From: Fauci, Anthony (NIH/NIAIO) [E)Sent: Thu, 6 Feb 2020 14:24:54 +0000To: Billet, Courtney (NIH/NIAID) [E]Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer(NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E]Subject: RE: ASF: for review, Azar coronavirus presser remarksAttachments: Secretary's remarks with minor Fauci edits.docxHere are my edits for Azar' s press commentsAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [E] (b)(6)Sent: Thursday, February 6, 2020 7-:2-9 -A-M- ---=-<~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El(b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>M1;a rston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)>Subject: ASF: for review , Azar coronavirus presser remarksPis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed.They also would like talking points from us, covering what you would say. These are really just aplaceholder. We could resubmit what we sent last time. Is there anything new you would anticipatesaying?From: "Brennan, Patrick (05/ASPA)" --------- Date: Wednesday, February 5, 2020 at 11:25 :33 PMTo: "Routh, Jennifer (NIH/NIAID) [El" (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)"(b)( >, "Galatas, Kate (CD"C.:'/.O":-::-D-::-/:-O::-A:-:D:-C::77)' ': -::==.,......(.b.)(.6.), "Fine, Amanda (NIH/OD) [E]" =====::::!.--=-=-~ -------- (b)(6)>, "Conrad, Patricia (NIH/NIAID) [El" (b)(6J>, "Kane, EIieenNIH-002116(OS/A SPR/OEA)" CbH6J>",M ichael, Gret chen (OS/ASPR/OEA)",;._..;___..;______;_::::==' (:b;);:(:6;=,)a>-",-,:,::B-"'i~.lle- t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele,Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" (b) (6)>,"Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)"(b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather(FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1,"McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)"CbH , "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)"----:~~====~(b:)_(6)_>,_ "K-e~ve.n.e;y,,· Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)>Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]"-------- (b)(6)>, "ASPA-Deputies" <ASPA-Deputies@hhs.gov > Subject : For review by 11 AM Thurs: Sec. Azar coronavirus presser remarksHi all,Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled pressconference on coronavirus- after which the plan is for Dr. Redfield and then Dr. Fauci, and thenwhoever from State and OHS (I think?) to speak.Can CDC, NIAID, OGC, FDA, and ASPR let me know if this looks OK by 11 AM tomorrow?And once CDC and NIAID have their draft TPs, it would be great to see those as well.Thank you!- PatrickNIH-002117From: Fauci, Anthony (NIH/NIAID) [ElSent : Thu, 6 Feb 2020 03:59:18 +0000To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [ElCc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence(HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda,Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA)Subject: RE: Coronavirus collaborating centerYes. Thanks you.-----Original Message----From:Grigsby , Garrett (HHS/OS/OGA) --------- (b) (6)>Sent: Wednesday , February 5, 2020 8:-42- A-t'-vl- -, ,,.,..,-= To: Fauci, Anthony (NIH/NIAJD) [E] (b)( >; Lane, Cliff (NTH/NJACD) [E]------(b)-(6) - ------- Cc: Marston , Hilary (NTH/NTATD[)E ] (b)(6) ; Zebley, Kyle (HHS/OS/OGA)....................... ----, (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara(HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff, Colin(HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ;Alexander, Thomas (OS/OGA) ---,---------(b) (6)> Subject: FW: Coronavirus collaborat ing centerlmportance: HighDrsF & L,Confinning that you want me to reply in the affirmative asap ... ?-----Original Message----from: Lamourelle , Gabrielle (HHS/OS/OGA) __________ (b)(6_), >Sent: Wednesday , Febrnary 5, 2020 6:5-0- A-M-- -~ ~= To: Grigsby , Garrett (HHS/OS/OGA) -------(b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA) (b) ( >; Burr, Mara(HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) (Cc: Tracy Carson (b)( ; Smith, Steven T (Geneva) (b) ( art, Jessica L.(HHS/OS/OGA) Cb) C ; Levine, Maya (OS/OGA) (b ood, Rachel(HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) --------- Subject: FW: Coronavirus collaborat ing centerlmportance: HighDear Garrett and all,I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with therequest that we review and provide a reply as quickly as possible. The letter, as usual form, says they will goforward in 8 weeks if they hear no objection from us.Thank you,Gabrielle-----Original Message--------- --,;-;= From: TULER, Matias Cb()6 )Sent: Wednesday , February 5, 2020 9:35 AM(b) (5)If you have any questions, let me know.NIH-002145To: Lamourelle, Gabrielle (HHS/0S /OGA)Cc: OGA Multilateral <OGAmu ltilateral@hhs.gov >Subject: RE: Coronavirus collaborating centerDear Gabrielle ,Many thanks for the email.(b)(1 sent you an email with the letter just after we talked. 1 do not know if you received it. ram attaching the letter tothis email again, just in case.Thank you very much in advance.Best regards ,MatiasMatia s TulerProgramme ManagerWHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health OrganizationGeneva , SwitzerlandOffice: (b) (6)Web: http://www .who.int/collabora tingcentre s/infonnat ion/en/http://www .who.i nt/about/collabo rations/expert panels/en/Follow WHO on Facebook, Twitter, YouTube, Instagram-----Original Message- ----From: Lamourelle , Gabrielle (HHS/0S /OGA) -----------(b-)(6) > Sent: Wednesday , February 5, 2020 9: 17To: TULER, Matias (b)(6)Cc: OGA Multilateral <OGArnu ltilateral @hhs.gov>Subje ct: Coronaviru s collaborating centerDear Matias,Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electroniccopy as well and J will send back immediately to our office for a rapid reply.With best wishes,Gabrielle LamourelleDeputy Director, Multilateral RelationsHHS Office of Global AffairsSent from my iPhoneNIH-002146From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAID) [E)Thu, 6 Feb 2020 02:55:19 +0000Kerr, Lawrence (HHS/0S/OGA)Grigsby, Garrett (HHS/0S/OGA)RE: Spoke with Soumya re: evolut ionary origin of nCoVI do not see any prob lem with your doing this. Go for it.Best,TonyFrom: Kerr, Lawrence (HHS/0S/OGA) ---------- Sent : Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( >Cc: Grigsby, Garrett (HHS/OS/OGA'")=======~ ("b")'~(6)>Subject: Spoke with Soumya re: evolut ionary origin of nCoVDr. Fauci,I welcome you r advice please . Much thanks,LarryNIH-002149(b) (5)From:Sent :To:(b)(6)Wed, 11 Mar 2020 19:30 :25 -0400John M JessupSubject: Re: You are great - a thoughtKim:Thanks for the note. That is exactly what the cdc is sta1i ing to do.Best,TonyOn Mar 11, 2020, at 7:22 PM, John M Jessup --------- (b)(6) wrote:Tony,We have seen each othe r over the decades. I am the (b)(6) from NCIwho decreid the lack of info rmation about Eboal since it was limited to fruit bats as areservoir.An idea about testing . Maryland sti ll has testing limited to subjects withsymptoms who have contact with people from affec ted areas or who real ly ill with arespiratory infectionWhy not forget the contacts and test those with flu-like symptoms without theneed for contacts but instead test for flu and if that is negative move on to covid -19.That would still be a tr emendous demand so ... go to a formal two -ti er t est wh erePCR is done with approved PCR primers and if that is positive then the confirmation is witha FDA test for covid -19.There are a lot of manufacturers of PCR primers, most clinical labs have PCRmachines so that screening tests ought to be supported wit hout a lengthy FDA clearance ifit w innows the number of patients who need a formal test.You are terrific . Keep it up with common sense as opposed to whatever the top ofthe administration suggests. I bet that the primer manufacturers would be supportive .KimJ. Milburn Jessup, MD, FACSResearch ScientistDivision of ResearchWashington DCVAMC50 Irving Street NWWashington, DC 20422(b)(6) or_ ______ (°b" )'""(=6' )Affil iate Professor - Systems BiologyNIH-000677College of ScienceGeorge Mason University(b)(6)----(b)(-6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIHNIH-000678From: (b)(6)Sent : Wed, 5 Feb 2020 08:56:13 -0500To: Baden, Lindsey, M.D .Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea(NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E]Subject: Re: favor(b) (6). (b) (4)On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M.D. <lbaden@nejm.org>wrote:Ton'l,'------------------------- (,.b.)".(,"6 )..(b." )' .~.,.l. ,LindseyFrom : "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6)Date: Tuesday, February 4, 2020 at 7:06 PMTo: "Baden, Lindsey, M .D." <lbaden@ne j m.org>--------~= Cc: "Marston, Hilary (NIH/NIAID) [E]" CbH6")C onrad, Patricia(NIH/ NIAID) [E]" Cb)( , "Lerner, Andrea (NIH/ NIAID) [E]",;.__:_ _ __;_...:......:...(~.b:):~:C=;;6-,-)-,:,: -L:-a- n-e-, -c=:l:if-:f:: --(: N--::1--:H:---/:N-'. IAID) [El" (b)(6)> ,"Mo rens, David (NIH/N IAID) [El" CbH6)>Subject : RE: favorLindse :Best regards,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-03NIH-002173(b) (6). (b) (4)31 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: Cb()6 )FAX: (301) 496-4409E-mail: (b) (6)The information in this e-mail and any of its attachments is confidential and maycontain sensit ive information . It should not be used by anyone who is not the originalintended recipient. If you have received this e-mail in error please inform the senderand delete it from your mailbox or any other storage devices. The National Institute ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender 's own and not express ly made on behalf of the NIAID byone of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm.org>Sent: Tuesday, February 4, 2020 3:3-5- P-M- -----=-c-c= To: Fauci, Anthony (NIH/NIAID) [E)" ======= (b=)( :6:-)!~Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6); Conrad, Patricia(NIH/NIAID) [E] (b)(6)Subject: Re: favorTony (and Hilary),Much appreciated. ------- (b) (6), (b) (4) .Thank you,LindseyFrom : "Fauci, Anthony (NIH/NIAID) [E]" --------- (b)(6)Date: Tuesday, February 4, 2020 at 2:16 PMTo : "Baden, Lindsey, M.D." <lbaden@nejm.org >Cc: "Marston, Hilary (NIH/NIAID) [E]" J CbC)6 J, "Conrad, Patricia(NIH/N IAID) [E]" (b)(6)Subject: RE: favorLindsa :TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthNIH-002174(b) (6), (b) (4)Bethesda , MD 20892-2520Phone: Cb) (6)FAX: (301) 496-4409E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confidential and maycontain sensitive information . It should not be used by anyone who is not the originalintended recipient. If you have received this e-mail in error please inform the senderand delete it from your mailbox or any other storage devices . The National Institute ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender's own and not expressly made on behalf of the NIAID byone of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm.org >Sent: Tuesday, February 4, 2020 12-:3-1- P-M- ---::-:-c-= To: Fauci, Anthony (NIH/NIAID) [E)- ------- (b)(6) Subje ct: favorTonv.Thank you for considering,Lindsey(b) (6). (b) (4)This email message is a private communication. The information transmitted, includingattachments, is intended only for the person or entity to which it is addressed and maycontain confidential, privileged, and/or proprietary mater ial. Any review, duplication,retransm ission, distribution, or other use of, or ta king of any action in reliance upon, thisinformation by persons or entities other than the intended recipient is unauthorized by thesender and is prohibited . If you have received this message in error, please contact thesender immed iately by return email and delete the original message from all computersystems. Thank you.This email message is a private communication . The information transmitted, includingattachments, is intended only for the person or entity to which it is addressed and maycontain confidential , privileged, and/or proprietary mater ial. Any review, duplication,retransm ission, distribution, or other use of, or taking of any action in reliance upon, thisinformation by persons or entities other than the intended recipient is unauthorized by thesender and is prohibited. If you have received this message in error, please contact thesender immed iately by return email and delete the original message from all computersystems. Thank you.This email message is a private communication. The infonnation transmitted ,including attachments, is intended only for the person or entity to which it isaddressed and may contain confidential, privileged , and/or proprietary materia l. Anyreview, duplication , retransmis sion, distr ibution , or other use of, or taking of anyaction in reliance upon, this information by person s or entities other than theintended recipient is unauthorized by the sender and is prohibited. If you haveNIH-002175NIH-002176received this message in error, please contact the sender immediately by returnemail and delete the original message from all computer systems. Thank you.From:Sent :To:(b)(6)Wed, 5 Feb 2020 08:41:40 -0500Baden, Lindsey, M.D .Subject: Re: favorThanks , Lindsey. I am always happy to help in any way I canOn Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M.D. <lbaden@nejm.org>wrote:Tony,On a different note, as the spread of the nCoV-2019 virus is so complex and fast moving,any advice on how we at the Journal can help in the response would be great.Your advice is always appreciated as we all try to get it right and be responsive.LindseyFrom: "Fauci, Anthony (NIH/N IAID) [E]" ---------- (b)(6)Date: Tuesday, February 4, 2020 at 7:06 PMTo: "Baden, Lindsey, M .D." <lbaden@nejm.org> -------- == Cc: "Marston, Hilary (NIH/ NIAID) [E]" (b)(6), "Conrad, Patricia(NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]"~___;_ _ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- .--------- CbH >, "Lane, Cliff (NIH/ NIAID) [El" CbH6) "Mo rens, David (NIH/N IAID) [EJ' (b)(6)Subject : RE: favorLindsey:Best regar ds,TonyAnthony S. Fauci, MDDirectorNat ional Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520Nat ional Institutes of HealthBethesda , MD 20892-2520NIH-002177(b) (6). (b) (4)Phone: Cb) (FAX: (301) 496-4409E-mail: (b)(6) --------- The information in this e-mail and any of its attachments is confidential and maycontain sensitive information . It should not be used by anyone who is not the originalintended recipient. If you have received this e-mail in error please inform the senderand delete it from your mailbox or any other storage devices . The National Institute ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender's own and not expressly made on behalf of the NIAID byone of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm.org>Sent: Tuesday, February 4, 2020 3:35 PMTo: Fauci, Anthony (NIH/NIAID) [E) -------=- (b')"("='6)Cc: Marston, Hila ry (NIH/NIAID) [E) CbH ; Conrad, Patricia(NIH/NIAID) [E] (b)(6)>Subject: Re: favorTony (and Hilary), ---- ~=--c~= Much appreciated -------(b)-(6) . (b)(4). Thank you,LindseyFrom: "Fauci, Anthony (NIH/ NIAID) [E]" ---------- (b)(6)Date: Tuesday, February 4, 2020 at 2:16 PMTo: "Baden, Lindsey, M.D." <lbaden@nejm .org>Cc: "Marston, Hilary (NIH/NIAID) [E]" (b)(6), "Conrad, Patricia(NIH/NIAID) [E]" CbH6)Subject: RE: favorLindsay:TonyAnt hony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31 , Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone : Cb()6 )NIH-002178(b) (6). (b) (4)FAX: (301) 496-4409E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confidential and maycontain sensitive information . It should not be used by anyone who is not the originalintended recipient. If you have received this e-mail in error please inform the senderand delete it from your mailbox or any other storage devices. The National Institute ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender's own and not expressly made on behalf of the NIAID byone of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm.o rg>Sent: Tuesday, February 4, 2020 12:31 PM ------~~ To : Fauci, Anthony (NIH/NIAID) [E) (b)(6)>Subject: favorTon ~-------------------------- ~(b~~=(6)~. ~(b) ~(=~Thank you for considering,LindseyThis email message is a private communication . The information transmitted, includingattachments, is intended only for the person or entity to which it is addressed and maycontain confidential, privileged, and/or proprietary mate rial. Any review, duplication,retransm ission, distribution, or other use of, or taking of any action in reliance upon, thisinformation by persons or ent ities other than the intended recipient is unauthorized by thesender and is prohibited . If you have received this message in error, please contact thesender immed iately by return email and delete the original message from all computersystems. Thank you.This email message is a private communication . The information transmitted, includingattachments, is intended only for the person or entity to which it is addressed and maycontain confidential, privileged, and/or proprietary material. Any review, duplication,retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, thisinformation by persons or entities other than the intended recipient is unauthorized by thesender and is prohibited. If you have received this message in error, please contact thesender immed iately by return email and delete the original message from all computersystems. Thank you.This email message is a private communication. The infomrntion transmitted,including attachments, is intended only for the person or entity to which it isaddressed and may contain confidential, privileg ed, and/or propri etary material. Anyreview, duplication , retransmis sion, dis tribution, or other use of, or taking of anyaction in reliance upon, this information by persons or entities other than theintended recipient is unauthorized by the sender and is prohibited. If you havereceived this message in error, please contact the sender immediately by returnemail and delete the origi nal mes sage from all compute r systems . Thank you.NIH-002179From:Sent :To:Subje ct:For discussion.Fauci, Anthony {NIH/NIAID) [ElWed, 5 Feb 2020 11:52:41 +0000Conrad, Patricia {NIH/NIAID) [ElFW: INTERVIEW-A HABER/ A NEWSFrom: GULSEN EDA ULUSOY <EDA.ULUSOY@ahaber .com .tr>Sent: Wednesday, February 5, 2020 3:23 AM --------=-:-= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) _______ _,Subject : INTERVIEW-A HABER/ A NEWSDear Mr. Fauci,This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News.We wou ld like to take few minutes of your time and kindly ask if we could possibly have theopportunity to make a Skype interview with you about China coronavirus outbreak.We can have the interview this week or next week. I can arrange it according to yourprogramme.It will on ly take 15 minutes of your time.We would really apprecia te if we can make this interview.Thank you for your kind consideration.I'm look ing forward to your reply.Sincerely,Eda UlusoyCorrespondentNIH-002180From:Sent :To:Subject ::et us discuss.Fauci, Anthony (NIH/NIAID) [E)Wed, 5 Feb 2020 11:52:11 +0000Conrad, Patricia (NIH/NIAID) [E)FW: Interview invitation from Dialogue CGTNFrom: Bai Jacinta (b)(6)Sent: Wednesday, February 5, 2020 2:58 AM To: Fauci, Anthony (NIH/NIAID) [E] -------------- -(-b)=( =>;, F auci, Anthony {NIH/N IAID) [E] (b )( 6) >Subj ec t : Interview invitation from Dialogue CGTNDear Mr. Fauci,This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well.I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time.I read the interview to you on New York Times and sincerely wish that you could share more with ourglobal audience. It would be our honor to have you on.Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling theoutbreak, cooperat ion in international communities, prevention measures and so on.Please kindly let me know if you are available for the show . I'll send the proposed questions beforehandand book the closest studio for you.Appreciate it!Best,Jacinta BaiDialogue, CGTNNIH-002181From:Sent :To:Cc:Subje ct:David:Fauci, Anthony (NIH/NIAID) [E)Wed, 5 Feb 2020 11:34:46 +0000Ho, David D.Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [ClRE: 2019-nCo\/Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad(copied here) to set up a call. I down at the Congress and White House most of the day, but wecan probably squeeze a call in between meetings .Best,TonyFrom: Ho, David D (b)(6)>Sent: Tuesday, February 4, 2020 12:48 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>Subject: 2019-nCoVTony,Greet ings. As you can see below, our institute has moved. We are now part of Columbia.Do you have a brief moment to chat about the new coronavirus?Best,DavidDavid D. Ho, M.D.Director, Aaron Diamond AIDS Research CenterClyde and Helen Wu Professor of MedicineDirector, Wu Family China CenterColumbia University Vagelos College of Physicians and Surgeons701 W. 168th Street, HHSC 1102New York , NY 10032NIH-002182From: Fauci, Anthony (NIH/NIAIO) [ElSent : Wed, 5 Feb 2020 11:17:05 +0000To: Collins, Francis (NIH/OD) [ElCc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia(NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID)(b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) --------- Subject: RE: CoronavirusFrancis:(b)(5)-------------- (b)(5) Happy to discuss further. Thanks,TonyFrom: Coll ins, Francis (NIH/OD) [ElSent : Wednesday, February 5, 2020 5:58 AM(b)(6)------~~ To: Fauci, Anthony (NIH/NIAID) [E;] !====== (b=)-(;~6)~Cc: Tabak, Lawrence (NIH/OD) [El CbH6)>; Shapiro, Neil {NIH/OD) [El(b)(6)Subject: FW: CoronavirusImport ance: HighHey there Tony,Thanks, FrancisFrom: Shapiro, Neil (NIH/OD) [El -------- (b)(6)> Sent: Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins, Francis (NIH/OD) [El CbH6)>; Tabak, Lawrence (NIH/OD) [El(b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6)Schwetz, Ta r,a_ -(: N--::l--H::-7/:0:-:D:-:)-:[-=E:l:.:====---...,_ (b,.). _=(.6.)>NIH-002183(b) (5)Cc: Shaya, Cecile {NIH/OD) [El (b)(6) ______._...Subject: RE: CoronavirusImport ance: HighFrom: Shapiro, Neil {NIH/OD) [ElSent: Tuesday, February 4, 2020 4:46 PMTo: Collins, Francis {NIH/OD) [E]----- -(-b=")'(-"="6J>; Tabak, Lawrence (NIH/OD) [El(b) (5)--~~~~====!(b:),( _; _Jo-hn~so~n, Alfred (NIH/OD) [El (b)(6)>; Wolinetz, Carrie {NIH/OD) [El CbH6; JHallett , Adrienne (NIH/OD) [El (b)(6)Schwetz, Tar .a. .- (: N--::1--H::-7/:0:-D::-):-::[-:E:-l::--====::.;__--,;,- (b"HS=6"')"Cc: Shaya, Cecile {NIH/OD) [El ______(b)(._6.). .Subject: RE: CoronavirusFrancis,(b) (5)NeilNIH-002184From: Shapiro, Neil (NIH/OD) [E]Sent: Wed nesday, January 29, 2020 2:34 PMTo: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [ElCbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie":""."'."".""."-:-:-:-:-:-:::-====~~-~.;.,(NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)>Subject: RE: CoronavirusI'm sending them the first part, thanks .From: Collins, Francis (NIH/OD) [E] (b)(6)Sent: Wed nesday, January 29, 2020 5:23 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E) (b)(6) Shapiro, Neil (NIH/OD) [E)(b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie-~---~==:=:!.. __ __:_~=(NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6)Subject : RE: Coronavirus(b) (4)FCFrom: Tabak, Lawrence (NIH/OD) [El (b)(6)Sent: Tuesday, January 28, 2020 6:25 PM ------~= To: Shapiro, Neil (NIH/OD) [E] (b)(6) Collins, Francis (NIH/OD) [E](b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie(NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6)Subject : Re: Coronavirus(b)(5LarryFrom: "Shapiro, Neil (NIH/OD) [E]" --------- (b)(6)>Date : Tuesday, Jan uary 28, 2020 at 5:31 PMTo: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]"--------- CbH >, "Johnson, Alfred (NIH/OD) [E]" (b)(6) 11 W o Ii net z, Carrie (N IH/OD) [E]" CbH >, "Hallett, Adrienne (NIH /OD) [E]"(b)(Subject: Coronavirus(b)(5)NIH-002185(b) (5)NeilNIH-002186From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Wed, 5 Feb 2020 04:18:25 +0000To: Conrad, Patricia (NIH/NIAID) [ElSubject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meetingat the Ritz Carlton (22nd and M St. NW), Washington, D.C.No dinner.From: Conrad, Patricia (NIH/NIAID) [E] ---------(-b)(6)> Se nt: Tuesday, February 4, 2020 11:21 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6)Cc: Barasch, Kimberly (NIH/NIAID) ~[c::.========-- (cbc')"-("=6)Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the RitzCarlton (22nd and M St. NW), Washington, D.C.See highlight - will you and ---C-b><· a tt end the dinner. Pis advise.Patricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301 -496 -4409 faxDisclai mer:The informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information . It should not be usedby anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not acceptliability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives .From: Marlene Colucci <mcolucci@businesscouncil.com>Se nt: Friday, January 31, 2020 2:00 PMTo: Fauci, Anthony (NIH/NIAID) [E)-------= (b-)c(c-6-)=Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein<David.Rubenstein@carlyle.com>; MaryPat Decker <marypat.decker@carly le.com>Subject : Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton(22nd and M St. NW), Washington, D.C.Dear Dr. Fauci,NIH-002191On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of TheCarlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in ourmeet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade."{See form al invitat ion attached as well as list of CEO members).We would like for you to part icipate in a 50 minute fireside chat wi th David Rubenstein {and possibly Dr.Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade.We want to give our CEOs insights into what the next 10 years will bring in terms of detection, diagnosisand t reatment of diseases. All conversations are strictly off the record and closed press. We will coverall lodging and t ransportat ion.As you know, The Business Council is comprised of the chief executive officers of the largest globalcorporations, representing all segments of the economy . We expect at least 150 CEO members, spousesand speakers to be in attendance.As a participant you and your spouse are also invited to join us for our special reception, dinner andspeaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunityfor you to meet our CEO members and spouses, speakers and othe r special guests in an informalatmosphere.If you are interested and available, please let me know. We can also set up a very brief call with you todiscuss any additiona l details and answer any questions you may have. We look forward to hearingfrom you and wou ld be honored to have you participate with us again.Warmest regards,MarleneMarlene ColucciEXECUTIVEDIRECTOR'I B1USINESS~ COL \JClLT: 202-298-7650C Cb()6 )F: 202-785-0296NIH-002192From: Fauci, Anthony (NIH/NIAIO) [E)Wed, 5 Feb 2020 04:17:19 +0000Routh, Jennifer (NIH/NIAID) [E]Billet, Courtney (NIH/NIAID) [E]Sent:To:Cc:Subject: FW: Comment on story about how confident people feel about the ir govt'sresponse to a health epidemicPlease try to draft a response for me. Thanks .From: Rajeshni Naidu-Ghelani <Rajeshni.Naidu-Ghelani@ipsos.com>Sent: Tuesday, February 4, 2020 12:23 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------ (.b.-),-..(.,6=)Subject: Comment on story about how confident people feel about their govt's response to a healthepidemicHi Dr. Fauci,I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to howpeople responded to a recent global lpsos poll about the threat of a major health epidemic in theircountry in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 19-11/ a-more-dangerous-world -fear-2019.pdfI was hoping to get your comments on this, considering your expertise in infectious disease control.Below are some questions. If you could respond via email, that would be great as I am on a tightdeadline to get this story up. If it's easier to give you a call, I can do that as well. Please let me knowwhat works best. The story will be published on lpsos.com, on social media and our various countrywebsites. Thank you and I look forward to your response.1. In our survey of more than 18,500 people in 28 countries done in late last summer, more thanhalf (51%) of people said there was threat of a major health epidemic in their country in the next12 months with people in emerging markets at the top of the list. Are you surprised by thisresult? It's among the highest reading for this question since the Ebola outbreak in 2014 whenthe percentage climbed to 59%.2. The U.S. is the only developed country in the top 10 list where most people think a major healthepidemic will occur. Why do you think this is?3. A follow up question to the previous one is how confident people are that their governmentcould protect them or respond effectively if such an outbreak was to occur. Over half globallysaid they were confident in their gov't's response. Do you think people have a lot of trust inthose in power to do the right thing in times of an outbreak?4. Seven of the top 10 countries where people had the most confidence in govts are in thedeveloped world . How important are developed healthcare systems when it comes to outbreakslike the coronavirus?5. Likewise, many countries at the bottom of this list are emerging markets. What can govts inthese countries do to ease peoples' fears on how they are or will handle an outbreak like thecoronavirus?NIH-0021936. How difficult is it for governments and health officials to prevent the spreading of a virus likethis before it becomes a pandemic? What measures can be taken?Please free to add any add itional information that you thin k may be relevant . I hope to hear from yousoon.Regards,RajeshniRajeshni Naidu-Ghelani I Data JournalistPublic Affairs160 Bloor Street East, Suite 300M4W 189 Toronto - CanadaPhone: +1416 572 5143Mobile: ,.._ __ ...>;;<~rajesbni .naidu-ghelani@ipsos.comwww.ipsos.comCtt,\NQE THE OAt.'!1GAMECHANGERS IINIH-002194From: Fauci, Anthony (NIH/NIAID) [E)Sent : Wed, 5 Feb 2020 04:12:18 +0000To: Routh, Jennifer (NIH/NIAID) [E]Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia(NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E]Subject : RE: for review: responses for Elemental news site (not urgent)I made some modifications. You can send it. Thanks.From: Routh, Jennifer (NIH/NIAID) [E) (b)( >Sent: Tuesday, February 4, 2020 4:11 PMTo: Fauci, Anthony (NIH/NIAID) [E]_ _____ ('"b'~..-(.6=) >Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E](b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg(NIH/NIAID) [E) (b)(6)Subject : for review: responses for Elemental news site (not urgent)Dr. Fauci -This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellnessnews site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have draftedproposed responses for you in red below . Please let me know if you have edits. I will send responsesback to the reporter attributed to you.Thanks,JenFrom: Rob Britt (b) (6)Sent: Sunday, February 2, 2020 5:1-0 -P-M- -- ---..-,~ To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)(6J> Subject: Coronavirus - reporter's questionsHi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual andlevel-headed, and I have seen your comments on NPR Friday and in the NY Times over theweekend , so I hope you could comment very briefly for our story:-- What's your expectation for whether this will become a pandemic?The novel coronavirus outbreak will likely become a pandemic. We know the virus is verytransmissible. The infection continues to accelerate and there is efficient transmission inchina. If sustained transm ission also occurs in other countries throughout the world, theoutbreak would fulfill the definitive of a pandemic-- Pandemic does not necessarily equate to a terrible situation, compared to, say bad fluseasons. What 's your expectation on the potential severity of this coronavirus?It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remainslow, if it is easily t ransmissible, the global impact can be significant .-- And your suggestion to people in the U.S. who might be very concerned?NIH-002195We are treating t he emergence of a novel coronavirus as a very serious public healththreat. However, the risk to the general Amer ican publ ic remains low at this time . Weunderstand that people may be wor ried . We ask that people not let fear or panic guidethe ir actions .Thanks for any help you can provide.Cheers,RobRobert Roy BrittTop Writer on Medium in Science & Health.Contributor to OneZero (science) & Elementa l (health).Former editor-in-chief of Live Science and Space.com.(b)(6)(b)(6)NIH-002196From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Wed, 5 Feb 2020 04:06:33 +0000Cassetti, Cristina (NIH/NIAID) [E]Subject: FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr.Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concernsPlease handle.-----Original Message-----From: Jon M (b) (61Sent: Tuesday, February 4, 2020 4:55 -PM- ------, a-s-r,= To: Fauci, Anthony (NTH/NlAID) [E] (b) ~Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo Clinic)regar ding Chinese 15 minute Coronavirus test and other concernsFrom: Jon M (b) (6}To: ocpostoffice@niaid .nih.govSubject: Atten tion Meylin - Forward of my email lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci(NlAID/NII-1}Date: Feb 4, 2020 I :45 PMHello Meylin,Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of hisassistant, Joseph Roberts, to Dr. Fauci.Jon MarkowitzFrom : Jon M (b) (61To: (b)(6)Subject: JOE -We spoke on phone today ... Please forward my email with reference links to Dr. Gregory PolandDate: Feb 4, 2020 12:57 PMHello Joseph Roberts (Mayo Clinic),We spoke on phone today ...Please forward my email with reference links to Dr. Gregory Poland Thank you, Jon MarkowitzFeb 4 , 2020Dear Dr. Gregory PolandI saw your appearance Feb 3 on a CNBC news program:https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4'We're basically at a pandemic now' : Mayo Clinic physician on corooavirusFyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 yearsold and live in Los Angeles.A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there wereefforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical theNIH-002197NIH-002198White House arrange for the new Chinese test to be available in the US everywhere immediately.This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY.At this point, the NTH, CDC and White House shou ld have already obtained the Chinese 15 minute test for the virusand implement at all US medical centers and airports receiving travele rs from the infectious regions.Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know theyare infectious, whether returning from infection zones or are infected by others already here, I am hoping you andother infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all otheragencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country byair and sea with the Chinese 15 minute test as well as pull out all the stops to develop an even quicker test that'sportable.As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks fromincreasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on theprecipice of an unstopable runaway epidemic.What is also desperately needed from the federal government are frank and honest recommendations regarding whatis necessary to prevent becoming infected such as:surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipesalong with specific protocols on how not to bring the vims particles back to ones car, borne and possessions.It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators beramped up to huge scale. Without adequate numbers of these, exam gloves and eye protection this country will notbe capable of containing this epidemic .Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce.Thank you very much for your attention to this issue.Jon MarkowitzLos AngelesReferences:https://www .rt.com/news /4 79705-china-develop-coronav irus-rap id-test/China develop s rapid Coronavirus test that works in under 15 MINUTES3 I Jan, 2020 I 0:48Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus inunder fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction.Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institutefor Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to theXinhua news agency.The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rateof 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further.The first batch of kits has reportedly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan ,in Hubei province.https://www.youtube.com/watch?v=Wg33oZd0- R4'We're basically at a pandemic now': Mayo Clinic physician on coronavirus114,173 viewsNIH-002199•Feb 3, 2020CNBC Televisionhttps://www.youtube.com/watch?v=VdUi kwuw7T11 confinned US coronavirus cases, experts warn of pandemic I ABC News157,773 views•Feb 3, 2020ABC Newshttps://www.youtube.com/wa tch?v=8Hjy3UfaTScCoronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate129,190 views•Feb 3, 2020MedCramhttps://www .youtube.com/watc h?v=GpbUoLvpdCoCoronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA329,919 views•Feb 2, 2020MedCramhttps://www.youtube.com/user/MEDCRAMv ideos/videosMedCram youtube channel[Dr. Roger Seheult - https://W'.vw.medcram .com/]https://www.youtube.com/watch?v=z05Z rMfKUDcCoronavirns , Contag ion and Complications228,007 views•Feb 2, 2020Dr. John Campbellhttps: //www.youtube.com/watch?v=u7D3AoNdp84Wuhan virus compared to MERS and SARS45,569 views•Feb 3, 2020Dr. John Campbellhttps://www.yo utube.com/user/Campbellteaching/videosDr. John Campbell youtube channe lhttps://www.youtu be.com/wa tch?v= zczkLZN 194Mayor de Blasio Holds Media Availability334 viewsFeb l , 2020NYC Mayor's Officehttps://,vww.youtube.com/wa tch?v=oMl-9Kvoj7OCoronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing]121,648 views•Streamed live on Jan 3 l, 2020QuickTake by BloombergFrom:Sent :To:Subject :Attachment s:Please handle.Fauci, Anthony (NIH/NIAID) [ElWed, 5 Feb 2020 04:03:41 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: coronavirusWuhan Coronavirus Vaccine.docxFrom: John Howard _________ C_>b<_·>Se nt: Tuesday, February 4, 2020 6:05 PMTo: Fauci, Anthony (NIH/NIAID) [E]_ _____ ..(,b,")("="6)Subject: coronavirusDear Dr, Fauchi,I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we mayhelp in this effort. (b)(4Thanks for your attention regarding this matter.Sincerely,John Howard, PhDPresident ABI(b)(6)NIH-002200,___ (,.b..)", ("4)"From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Wed, 5 Feb 2020 03:49:07 +0000Fleisher, Thomas (NIH/CC/OLM) [V)RE: QuestionNo problem.From:F leisher, Thomas (NIH/CC/OLM) (V) ------- (b) (6) > Sent: Tuesday, February 4, 2020 9:37 PMTo: Fauci, Anthony (NIH/NIAID) [E] -------=- CcHb-=- >Subject: Re: QuestionTony,Would you be willing to have your statement "we are in the middle of influenza season ... " included inthe Academy 's on line Practice Matters email Thursday going out to all members (attri buted to you)along with a link to the CDC webs ite devoted to Coronavirus?Thanks,TomFrom: "Fauci, Anthony (NIH/NIAID) (E)" (b)( >Date: Tuesday, February 4, 2020 at 3:14:47 PMTo: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- ~=Cc: "Conrad, Patricia (NIH/NIAID) [E]" --------- Subject: RE: QuestionTom:Right now nothing specific to communicate except that we are still in the middleof an influenza season and the things that we do to prevent spread of flu (i.e.hand washing, social distancing from crowds) are the same things that we woulddo if we have transmissions of nCoV here .Best,TonyAnthony s. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520Nation al Institutes of HealthBethesda , MD 20892-2520Phon e: (b)(6)FAX : (301) 496-4409E-mail : -------- (b)(6)NIH-002201The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Fleisher, Thomas (NIH/CC/DLM) [V] --------- (b) (6)>Sent: Tuesday, February 4, 2020 1:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E]- ------- CbH6J> Subject : QuestionTony,I was asked if th ere is any message th at the A&I community should receive in regards to the curr entCoronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medicalboards are releasing updates and recommendat ions but the question posed to me was is there anythingAAAAI should communicate to our membe rs? Thank you for considering this question.Regards,TomNIH-002202From:Sent:To:Subject:Sylvia:Fauci, Anthony (NIH/NIAIO) [ElWed, 5 Feb 2020 03:48:11 +0000Sylvia BurwellRE: A couple of quick quest ions.Masks are really for infected people to prevent them from spreading infection to people whoare not inf ected rather than protecting uninfected people from acquiring infection. The typ icalmask you buy in the drug store is not really effective in keeping out virus, which is small enoughto pass through the material. It might, however, provide some slight benefit in keep out grossdroplets if someone coughs or sneezes on you. I do not recommend that you wear a mask,particu larly since you are going to a vey low risk location. Your inst incts are correct, money isbest spent on medical countermeasures such as diagnostics and vaccines.Safe travels.Best regard s,TonyFrom: Sylvia Burwell (b)(6)>Sent : Tuesday, February 4, 2020 10:24 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6)Subject : A couple of quick questions .Begin forwarded message:From: Sylvia Burwell (b)(6)Date: February 4, 2020 at 9:35:03 PM ESTTo: Sylvia Burwell (b)(6)Subject: Fwd: Advice re a donationEXTERNAL EMAIL: Use caution with links and attachments.Begin forwarded message:From: Sylvia Burwell ----------- (b)(6)Date: February 4, 2020 at 9:33:47 PM ESTTo: Tony Fauci (b)(6)>Subject: Fwd: Advice re a donationNIH-002203TonyTwo quick questions1. I am travel ing to (b)(6) Folks aresuggesting I take a mask for the airport. Is this something I should do.2. Please see below. Do the Chinese have needs for support right now?Would money be better spent on diagnostics or vaccine work?Thanks!SylviaBegin forwarded message:From: Richard Falkenrath ---------- (b)(6) Date: February 4, 2020 at 5:27:32 PM ESTTo: (b)(6) Sylvia Mathews Burwell(b)(6)Subject: Advice re a donationHi SylviaI hope this find you well.Quick question, a little bit from left field, but drawing on yourexperience at Gates and HHS. Ray Dalio and Bridgewater areinterested in making a very sizable donation to help China dealwith the global public health challenge arising from the newcoronavirus. Any suggestions of where we should look todonate the funds?Thanks so much. ----------- (b) (6) looking forward to seeing you again soon.Richard(b)(6)NIH-002204From:Sent:To:Fauci, Anthony (NIH/NIAID) [E)Wed, 5 Feb 2020 00:42:06 +0000Conrad, Patricia (NIH/NIAID) [E)Subject : FW: Interview wi th Voice of AmericaLet us discuss.Anthony S. Fauci, MDDirectorNational Institu te of Allergy and Infectious DiseasesBuilding 31, Room 7 A-0331 Center Driv e, MSC 2520National Institu tes of HealthBethe sda , MD 20892-2520Phone: (b) (6)FAX: (301) 496-4409E-mail: (b)(6)The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. Itshould not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITorplease inform the sender and delete it from your mailbox or any other storage devices. The National Institute ofAllergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's ownand not expressly made on behalf of the NlAID by one of its representatives.-----Original Message-----From : Rattaphol Onsanit <ronsanit @voanews.com >Sent: Tuesday, February 4, 2020 2:42 P-M-- ---~~ To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) >Subject: Interview with Voice of AmericaDear Dr. Fauci,l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony yearsago.l'm now working on a news story about how developing countries equip themselves with medical readiness andpolicy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked atGlobal Health Sec11rity Index, Thailand was ranked the highest in its ability to tack le epidemics ahead of Japan ,Korea and Singapore. It's also by far the highest among developing countries.I'm curious to find out about contributing factors for developing countries' readiness to effectively handle anoutbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during thisoutbreak and T hope that this story could shed lights on tha t.If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would reallyappreciate the opportunity to speak with you again.Thank you,RattapholRattaphol "Ahn" OnsanilChief of VOA ThaiNIH-002205NIH-002206Sent from my iPhoneFrom: Fauci, Anthony (NIH/NIAIO) [E)Sent : Wed, 5 Feb 2020 00:31:31 +0000To: Messonnier, Nancy (CDC/DDID/NCIRD/0D)Subject : FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive after he drovetou rists from Wuhan, none of whom had exhibited severe symptomsNancy:See yellow highlight below . Did they misquote the CDC?Thanks,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who Is not the original Intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Folkers, Greg (NIH/N IAID) [E) -------- (b)(6)> Sent : Tuesday, February 4, 2020 12:12 PMTo: Fauci, Anthony (NIH/NIAID) [E)_ _____ _,(_b_ )- ,(-6=)Subject : WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan ,none of whom had exhibited severe symptomsFrom: Folkers, Greg {NIH/NIA ID) [E) -------- (b)( > Sent : Monday, February 3, 2020 1:50 PMSubject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus IsExperts Race to Figure Out How Contagiousthe Coronavirus IsNIH-002207The outbreak of novel coronavirus appears more contagiousthan seasonal flu and is on par with SARS in 2002 and 2003,studies sayChina says that as of Saturday there were 4,109 infected people in the city of Wuhan. Photo: chinadaily /ReutersByChao Deng andJeremy PageUpdated Feb. 2, 2020 7:34 pm ETBEIJING-Public-health experts around the world have been crunching numbers about the advance ofChina's dangerous new coronavi rus to estimate how far and fast it could spread.Studies published in recent days say the new virus appears to be more contagious than seasonal flu andon par with the simi lar pathogen behind an outbreak of severe acute respiratory syndrome in 2002 and2003. The new virus' mortality rate, however, is far below that of SARS.China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city wherethe outbreak began. Some scientists estimate based on statistical models that the number could be inthe tens of thousands.As health autho rities race to control the outbreak, they are also scrambling to figure out. based onimperfect data, how the virus is transmitted, the length of the incubation period and the degree towhich people without symptoms can spread the disease.China's health commission says incubation is generally between three and seven days, with the longestperiod being 14 days, and that people can spread the virus before appearing ill. That makes a two-weekNIH-002208NIH-002209quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks,the main screening method at immigration and other checkpoints."For a given level of transmissibility, more asymptomatic transmission makes a disease harder tocontrol," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London.The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China,says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity tospread from infected patients without symptoms to close contacts within about 6 feet.A study led by a researcher from Boston's Northeastern University-using mathematical probabilitymodels based on travel patterns and confirmed international cases-estimated the median number ofinfections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261.Professors at the University of Hong Kong using similar methods published a study in the Lancet onFriday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were stillin the hundreds."We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, saidJonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhannumbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu."Several recent studies published by scientists estimate that each person infected will, on average, infecttwo to three others. Epidemiologists call that the reproduction number .A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests theproblem is dwindling. Estimates of the reproduction number differ widely, with some studies usingprobability models and others based on regression analysis of cases over different time periods .Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the Universityof Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced."In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whomhad exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted thevirus after attending a training session with a colleague from China, according to the company . TheChinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she testedpositive for the new coronavirus.A study published in the New England Journal of Medicine study by Chinese authors including at theChinese Center for Disease Control and Prevention says the virus spread between people as early asmid-December. The researchers analyzed 425 patients, with more than half of the cases linked to theHua nan seafood wholesale market where authorities believe the virus first spread to humans from wildanimals.The researchers started identifying and collecting cases around the start of the year, by interviewingpatients, relatives and other close contacts. They estimated the reproduction number at 2.2 and saidthat the majority of patients weren't hospitalized unti l after five days of being ill.Researchers of recent studies cautioned that even their estimates of the virus' reproduction number arebased on early and incomplete data and only assess its potential to spread before trave l restrictions andother control measures begin. Thereafter, the reproduction number can vary depending on thosemeasures' effectiveness and other circumstances of the outbreak.Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though someoverseas experts have suggested the outbreak might not peak for several weeks.They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as manyother factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn'tspread that fast because there is a widely used vaccine.As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physicalintervention measures, including locking down entire cities and forced quarantine .NIH-002210Recent studies ind icate that stringent control measures will be needed not just in China, but in severalother countries, to curtail the outbreak ."This is unprecedented both in terms of the virus and the control measures that have been put in place,"says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine.- Raffaele Huang, Miho lnada and Ruth Bender contributed to this article.Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy.page@wsj.comCopyright ©2019 Dow Jones & Company, Inc. All Rights Reserved.87990cbe856818d5eddac44c7blcdeb8Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily representmy views nor those of NTATD, NIH, HHS, or the U.S. government .From : Fauci, Anthony (NIH/NIAIO) [E)Sent : Wed, 5 Feb 2020 00:05:35 +0000To: Baden, Lindsey, M.D .Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea(NIH/NIAID) [E] _____ Cb _H_6);Morens, David (NIH/NIAID) [E]Subj ect : RE: favorAtt achment s: ------------- (~b)~(6~).~(b~)~(4)Lindsey:Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail : (b)(6)(b) (6), (b) (4)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Baden, Lindsey, M.D.<lb aden@nejm.org>Sent ; Tuesday, February 4, 2020 3 :35 PMTo: Fauci, Anthony (NIH/NIAID) [E]_ _____ _(,_b)_. .( ,6.")""Cc: Marston , Hilary (NIH/NIAID) [E] _______ C_>b_C_6>) ; Conrad, Patricia (NIH/NIAID) [E]Subject : Re: favorTony (and Hilary),Much apprec iated .Thank you,Lindsey(b)(6)(b) (6), (b) (4). -------NIH-002211From: "Fauci, Anthony (NIH/ NIAID) [E]" --------- (b)(6)Date : Tuesday, February 4, 2020 at 2:16 PMTo: "Baden, Lindsey, M.D." <lbaden@ne jm.o rg>Cc: "Marston, Hilary (NIH/N IAID) [E]"- ---------Cb)( >, "Conrad, Patricia (NIH/N IAID) [ E]" (b) (6)Subject : RE: favorLindsay:TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : -------- (b)(6)(b) (6), (b) (4)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sende r's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Baden, Lindsey, M.D.< lbaden@nejm.org>(b)(6)Se nt: Tuesday, February 4, 2020 12:31 PMTo: Fauci, Anthony (NIH/NIAID) [E] -------- Subject: favor [~Thank you for considering,Lindsey(b) (6), (b) (4)This email message is a private communication . The information transmitted, including attachments, isintended only for the person or entity to which it is addressed and may contain confidentia l, privileged,and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, ortaking of any action in reliance upon, this information by persons or entities other than the intendedrecip ient is unauthorized by the sender and is proh ibited. If you have received this message in error,NIH-0022 12NIH-002213please contact the sender immediately by return email and delete the original message from allcomputer systems. Thank you.This email message is a private communication . The information transmitted, including attachments, isintended only for the person or entity to which it is addressed and may contain confidential, privileged,and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, ortaking of any action in reliance upon, this information by persons or entities other than the intendedrecipient is unauthorized by the sender and is prohibited. If you have received this message in error,please contact the sender immediately by return email and delete the original message from allcomputer systems. Thank you .From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 22:59:29 +0000Lane, Cliff (NIH/NIAID) [E)RE: favorThanks. Safe trave lsAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Lane, Cliff (NIH/NIAID) [El -------- (b)( >Sent: Tuesday, February 4, 2020 4:31 PM -------=-:~ TCoc:: MFaaursctio, nA,n thHoilnayry ((NNIIHH//NNIIAAIIDD)) [[EEll .-=-=-=-=-=-=-=-(=-b)(6~-)( b)=(6) Subject: Re: favor(b) (6), (b) (4)On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E]- -------- CbH6J>w rote: (b) (6), (b) (4)NIH-002218On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NIH/N IAID) [E] --------- (b)(6) wrote:Anthony S. Fauci , MDDirector. Thanks.National Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301) 496-4409E-mail -------- (b)(6)(b) (6), (b) (4)The information in this e-mail and any of its attachments is confidentialand may contain sensitive information . It should not be used by anyonewho is not the orig inal intended recipient. If you have received this emailin error please Inform the sender and delete it from your mailbox orany other storage devices . The National Institute of Allergy andInfectious Diseases (NIAID) shall not accept liability for any sta tementsmade that are the sender 's own and not expressly made on beha lf of theNIAID by one of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm .org>Sent : Tuesday, February 4, 2020 3:35 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc: Marston, Hilary (NIH/NIA ID) [E] >; Conrad,Patricia (NIH/N IAID) [E] (b)(6)Subject : Re: favorTony (and Hilary), Much appreciated. -------~-~-~-=-(b -)(6),( b)(4) Thank you ,LindseyFrom: "Fauci, Anthony (NIH/ NIAID) [E]"Date: Tuesd ay, February 4, 2020 at 2:16 PMTo: "Baden, Lindsey, M.D." <lbaden@nejm.org >(b)(6)>Cc: "Marston, Hilary (NIH/N IAID) [E]" CbH6J ...:--==========~;;- .."Conrad, Patricia (NIH/NIA ID) [E]" ---------- Cb)(6) Subject: RE: favo rNIH-002219Lindsay:TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7 A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301) 496-4409E-mail: (b)(6)(b) (6), (b) (4)The information in this e-ma il and any of its attachments is confidentialand may contain sensitive information . It should not be used by anyonewho is not the original intended recipient. If you have rece ived this emailin error please inform the sender and delete it from your mailbox orany other storage devi ces. The National Institute of Allergy andInfectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender's own and not expressly made on behalf of theNIAID by one of its representatives .From: Baden, Lindsey, M.D.< lbaden@ne jm.or g>Sent: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------~--~--- (b)(6=)> Subject: favorTonThank you for considering,Lindsey(b) (6), (b) (4)This email message is a private communication. The information transmitted,including attachments, is intended only for the person or entity to which it isaddressed and may contain confidential, privileged, and/or proprietarymate rial. Any review, duplication, retransmission, distribut ion, or other useof, or taking of any action in reliance upon, this information by persons orentities other than the intended recipient is unauthorized by the sender andis prohibited. If you have received this message in error, please contact thesender immediately by return email and delete the original message from allcomputer systems. Thank you.NIH-002220This email message is a private communication. The information transm itted,including attachments, is intended only for the person or ent ity to which it isaddressed and may contain confidential, privileged, and/or proprietarymater ial. Any review, duplication, retransmission , distribution, or other useof, or taking of any action in reliance upon, this informa tion by persons orent ities other than the intended recipient is unautho rized by the sender andis prohib ited. If you have received this message in error , please contact thesender immediately by return email and delete the original message from allcomputer systems. Thank you.(b) (6), (b) (4lNIH-002221From:Sent:To :Subject:Bob:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 21:28:48 +0000Seder, Robert (NIH/VRC) [E](b)(6)(b)(6) I am drowning here in ------------------------ coronavirus. Hope to talk to you soon.Best,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX : (301) 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.NIH-002222From :Sent :To:Subj ect :Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 21:0 1:39 +0000Conrad, Patricia (NIH/NIAID) [E)FW: Media Request: CBC NewsFYIAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Adam Miller <adam.miller@cbc.ca>Sent : Tuesday, February 4, 2020 3:5-5- -P-M-- -~~ To: Fauci, Anthony (NIH/NIAID) [E)- -------- (b)(6) Subject : Media Request: CBC NewsHi Dr. Fauci,I'm a senior writer with Canada's public broadcaster, CBC News, and I'm working on a national featurestory about the containment efforts of the coronavirus outbreak and what future scenarios could bepossible with the coronavirus globally.You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a fewminu tes by phone to talk about the possibi lity and implications of the outbreak becoming endemic.Would it be possible to speak briefly by phone this week? I would only need a few minutes of your timeand your expertise would be very beneficial for Canadians in the ir understand ing of this story .Thanks very much,AdamAdam MillerNIH-002223Senior Digital WriterCBC NewsDesk: 416-205-5719Cell: (b)(6)Twitter : @adamsmillerNIH-002224From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 20:46:18 +0000(b)(6)Subject: FW: favorAttachments :CbH6).CbH4J Thanks.Anthony S. Fauci , MDDirector(b) (6), (b) (4)National Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : Cb) (6)FAX : (301 496-4409E-mail : Cb) (6)(b) (6), (b) (4)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Baden, Lindsey, M.D.<lbaden@nejm.org>Sent: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '-==-=-==-=--~~ (b=)=(=6-)'!-=-,Cc: Marston, Hilary (NIH/NIAID) [E] Cb)( ; Conrad, Patricia (NIH/NIAID) [E)Subject: Re: favorTony (and Hilary),Much appreciated .Thank you,Lindsey(b)(6)-------(b)- (6), (b) (4)From: "Fauci, Anthony (NIH/NIAID) [E]" --------- (b)(6) Date: Tuesday , February 4, 2020 at 2:16 PMTo: "Baden, Lindsey, M.D." <lbaden@nejm.org>Cc: "Marston, Hilary (NIH/NIAID) [E]" ----------Cb)( >, "Conrad, Patricia (NIH/NIAID) [ E]" (b) (6)Subject: RE: favorNIH-002225Lindsay:TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)(b) (6), (b) (4)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or igina l intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm .org>Sent : Tuesday, February 4, 2020 12-:3-1- P-M- --=---c-c= To: Fauci, Anthony (NIH/NIAID) [E] ______ Cb _H_6)Subject : favorTonThank you for considering,Lindsey(b) (6), (b) (4)This email message is a private communication . The information transmitted, including attachments, isintended only for the person or entity to which it is addressed and may contain confidentia l, privileged,and/or proprietary material. Any review, duplication, retransmission, distribution, or othe r use of, ortaking of any action in reliance upon, this information by persons or entities other than the intendedrecipient is unauthorized by the sender and is prohibited . If you have received this message in error ,please contact the sender immediately by return email and delete the original message from allcomputer systems. Thank you.This email message is a private communication. The information transmitted, including attachments, isintended only for the person or entity to which it is addressed and may contain confidentia l, priv ileged,and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, ortaking of any action in reliance upon, this information by persons or entities other than the intendedrecipient is unauthorized by the sender and is prohibited. If you have received this message in error,please contact the sender immediately by return email and delete the original message from allcomputer systems. Thank you.NIH-002226From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 19:36:10 +0000Cassetti, Cristina (NIH/NIAID) [E]Subject: FW: Delivery Status Notification {Failure)Please t ake a look and handle.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone (b) (6)FAX: (301 496-4409E-mail : (b)(6lThe information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Robert Knobler Cb) (6) >Sent : Tuesday, February 4, 2020 1:-36- -P-M-- -~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)Subject : Fwd: Delivery Status Notification (Failure)------- --- Forwarded message -------- - From: Mail Delivery Subsystem -------------=""''"'(b")(- 6)= "Date: Tue, Feb 4, 2020 at 1:30 PMSubject : Delivery Status Notification (Fai lure)To: (b)(6)?•NIH-002231Address not foundYour message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail.The response fr om the remote server was:550 #5 . 1 . 0 Address r e j ected .------- --- Forwarded message -------- --From: Robert Knobler Cb) (6)Toi (b)(6) ----------- Cc:Bee:Date: Tue, 4 Feb 2020 13:29:23 -0500Subject: Potential Coronavirus ProphylaxisDear Dr. Fauci,You likely do not recall meeting me when I was looking at potentialfellowships in 1978, however, I never forgot your enthusiasm. I wentout to San Diego and worked with Mike Oldstone between 1979 and 11984.I did study a mouse coronavirus while there, mouse hepatitis virus(MHV) . I focused on genetic resistance, and eventually described amouse locus for susceptibi lity, which coded for the MHV receptor. Onto the present problem of human coronaviruses, Vaccines will take along time for the current crisis. The angiotens in convertin enzyme 2receptor has been ident ifed as the relevant human coronavirusreceptor. I am writing to suggest the investigation of ARBs aspotential blocking agents to either reduce or completely blockinfection. Perhaps this can be checked. There may sti ll be sufficientuntai nted suppl ies of ARBs, such as irbesar tan, available , orproduction can be scaled up, if this truly is the eve of a pandemic .Wish ing you success in th is endeavor. I am willing to cont ribu te inany way I can. Please feel free to contact me by e-mail or my cellphone .I did do clinical trial while with Mike, and then when I joined theNIH-002232neurology faculty of Jefferson in Philadelphia. I have been out on myown since December 1998, but I have never lost my interest in thiswork . I have some novel ideas on how HIV becomes AIDS, as well.All the Best,Robert L Knobler , MD, PhD(b)(6)(b)( CellNIH-002233From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Tue, 4 Feb 2020 15:54:25 +0000To: 00~Subject : FW: STAT: Quick retract ion of a faulty coronavirus paper was a good momentfor science http:/ /bit.ly/389QguMHeather:As per our recent conversation. This is your story (see below).Best,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who Is not the original Intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .The WatchdogsQuick retraction of a faulty coronavirus paperwas a good moment for scienceBy Ivan Oransky and Adam MarcusFebruary 3, 2020NIH-002237- -- ----• ,Hyacinth Empinado/STATAs fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory newpaper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted.Titled "Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag," thepaper claimed to find similarities between the new coronavirus and HIV, the virus that causes AIDS. Theuse of the word "uncanny" in the t itle, together with "unlikely to be fortuitous" in t he abstract, led someto th ink that the authors were suggesting the virus had somehow been engineered by humans.The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except thatit wasn't.The paper was almost immediately withdrawn, but not before plenty of handwringing from researcherswho complained that the appearance of such shoddy work on a preprint server without vetting by peerreviewers is precisely why the hoary old model of science publishing is better at keeping junk scienceout of the literature.Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to themenace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army ofpeer reviewers. And when these publications publish bad or erroneous research, it can take months oryears for the papers to be corrected or retracted - if they ever are.In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell,commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were atmost a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers aboutcoronavirus. Later Saturday, the authors commented on their paper, saying they were withdrawing it .And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors .They intend to revise it in response to comments received from the research community on theirtechnical approach and their interpre tation of the results."All of that happened before a single news outlet with any reach covered the paper, as best we can tell.But none of it was quite fast enough for some critics. "This is why preprints can be bad," said onescient ist on Twitte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints."What bugs me about this preprint is that had this manuscript undergone legitimate peer review, theseflaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories andfear surrounding this outbreak," Shiloh cont inued.History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bitmisplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet,one of the world's leading peer-reviewed medical journals. Other examples - including a paper by anNIH-002238NIH-002239intelligent design advocate questioning the validity of the second law of thermodynamics as it pertainedto evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year.Preprints can fill a void in times of rapidly changing scienceAnd even when peer-reviewed jou rnals do realize they've been had, retractions can take months oryears. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV didnot cause AIDS. We could go on, and the list includes papers that have never even been corrected.Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has aperfunctory screening process - sometimes acknowledge that journals have had to speed up theirgame to meet the pressures of an outbreak like coronavirus, or SARS in the early part of this century.Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said onTwitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers.Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed.Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly."Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The CoronavirusRace."Publishers have been looking for ways to score points against - and shut down - preprints for at leasthalf a century . Journals have speedily published a number of important papers on the new coronavirusalready, no doubt. Publishing industry champions are often quick to say that speedy peer review doesnot mean sloppy peer review - even in cases that requ ire massive correct ions.It now turns out that one of the world's leading peer-reviewed medical journals, the New EnglandJournal of Medicine, published a lette r last week about apparent coronavirus transmission from anasymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed,or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewedjournal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correctthe record.We'll see whether peer-review champions, who are often unwilling - with some notab le and welcomeexceptions - to acknowledge how slow and ineffective correction in science can be, note this apparentfailure of one of their gatekeepers. Doing so might, after all, make some people question the expensivesubscript ion deals universities agree to with publ ishers, as well as the article processing charges that canrun into the thousands of dollars for open access publications.Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to theexisting process that they can't admit its fl aws - or that it might be a good idea to also embracepreprint servers that could upend their business models. Just like in politics, maybe it's time to agreethat the publishing process is a messy one, and stop using single episodes, free of context, to scorepoints against one's rivals.This article has been updated with information about a flawed report in the New England Journal ofMedicine.Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily representmy views nor those of NIAID , NTH, HHS, or the U.S. government.From:Sent:To:(NIH/NIAID) [E]Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 15:03:33 +0000Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, EmilyCc: Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert(NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E]Subject: Universal coronavirus vaccineAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301) 496-4409E-mail: (b) (6)(b) (5)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .NIH-002240From:Sent:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 14:32:42 +0000To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID)[E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]Subject: FW: CoronavirusAtt achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx,JVP200011( 1). pdfFYI. Confid enti al for nowAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : Cb()6 )FAX: (301 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Howard Bauchner <Howard.Bauchner@jamanetwork.org>Sent : Tuesday, February 4, 2020 9:19 AM ------ -==-- To: Fauci, Anthony (NIH/NIAID) [E] (bH >Subject: FW: CoronavirusTonySee attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly tomention it on Thursday - thought you should see it.HCBFrom: Howard BauchnerSent: Tuesday, February 04, 2020 7:23 AMTo: Annette Flanagin <Annette.Fla nagin@jamanetwork .org>; Christiansen, Stacy<stacy.christ iansen@jama-arch ives.org>; Christopher Muth <Christopher . M uth@jama network .org>;Demetrios Kyriacou <Demet rios.Kyriacou@iamanetwo rk .org>; Edward Livingston--------------- CbH6>>F;o ntanaros, Phil <phil.fontanar osa@jama-archives.org>; Go I u b, Robert <robert.golu b@jama-a rchives.org>; Gregory CurfmanNIH-002241<Gregory.Curfman@jamanetwork.org >; howard.bauchner@jama-archives.org ; Jody Zylke<Jody.Zylke@jamanetwork .org>; McDermott, Mary (b)(6)>; Mike Berkwits<michael.be rkwits@jamanetwork .org>; (b)(6); Anne Cappola------------(b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark <David.Mark@ jam an et work .or g >; Demetrios Kyriacou <Demetrios.Kyr iacou@jamanetwork.o rg>; DerekAngus (b)(6)>; Feero, Greg CbH >; George O'Connor(b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) =====-~;"""'."' (b)(6); Joynt Maddox, Karen (b)(6) PreetiMalani (b)(6)>; Robert Golub <Robert.Golub@jamanetwo rk.org>; Saitz, Richard(b)(6) Schrag, Deborah,M.D. (b)(6)Tom Cole (b)(6)>; Winkel mayer, Wolfgang C. (b)(6);Armstrong, Katrina,M.D. (b)(6); Cutler, David (b) (6); Eric--- (b)(6J>; Goldman,L ee~ -.:-:=======~~ ':-:---:::--~==(b)=(6)=Jo=hn ~Wo-n-g~~ E u Li (Div Head, Med Dep..t.). ..:.c========~~,;-" >; Josh Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant,Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' ------=--:-:-= (b)(6); Steven E. Nissen (b)(6)>; Vokes,Everett [MED] (b)( Zeke ----=-.========~--------===========~--- Em an u e I (b)(6)>; Andy Josephson (b)(6)-----.=======~~------ (b)(6) Bonow, Robe_rt, .M:..D._. _..!====(=b)~(6)~ ~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH ---------- (b)(6) =====->_; D;i_sis_, N._o,ra; _ _._:: ::======~::(b;):(6.;).;>.-; .F- re=d R-i-vara, MD (b)(6); Ongur, Dost;- :R:"i:t.-a--=R--ed-:b--:e--rg- ,-:M--:-D=.-:::::::==~ (b)(6l)>; Shinkai, Kanade(b)(6)======== (~b)- (6~)Subject : CoronavirusSo a quick update.Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. Theyworked on it this weekend - thanks to both .Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemic- but is definite lyrelated. Going up this week.- it will be published on Friday. A big thank you to Phil and Derek.A Rl has also been accepted - it wi ll go up Thursday.I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to processmanuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) andEd have been a big help.As we have done in the past everything wi ll be free to the world.NIH-002242I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony- as I have said many times - is a national treasure.(b) (4)All that said we are definitely interested in novel research report (many can be research letters) . Just letme know .HCBHoward Bauchner, MDEdito r in Chief, JAMA and The JAMA NetworkEmail: howard.bauchner@ jamanetwork.orgTelephone: 312-464-2400Please respect the confidential nature of this email.For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinterviewsNIH-002243From:Sent:To:Cc:Subject :Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 14:09:40 +0000Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E]Haskins, Melinda (NIH/NIAID) [E);NIAID OD AMRE: Thanks and filmingI am leaving it up to you all to determine what is doable, feasible and/orappropr iate . We can discuss at our OD AM meeting .Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave rece ived this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6)Sent: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]-_ -_-_-_-_-_~ = C_Hb_ ; Conrad, Patr icia (NIH/NIAID) [E)(b)(6)>Cc: Haskins, Melinda (NIH/NIAID) [E) _______ CbH_.>; NIAID OD AM<NIAIDODAM@niaid.nih .gov>Subject: RE: Thanks and filmingJust to kee in mind: (b) (4), (b) (5)(b) (4), (b) (5)From: Fauci, Anthony (NIH/NIAID) [E] _______ (b)(.6..),Sent: Tuesday, February 4, 2020 6:42 AM -------~~ To: Conrad, Patricia (NIH/NIA IO) [E)- --------- (b)(6)>; NIAID OD AM <NI A ID OD AM@ n i aid . n i h, gov>Cc: Haskins, Melinda (NIH/NIAID) [E] -------- (b)( >Subject : RE: Thanks and filmingNIH-002244OKFrom: Conrad, Patricia (NIH/NIAID) [E]- ------- (b)(6)> Sent: Tuesday, February 4, 2020 6:35 AM(b)(6)To: NIAID OD AM <NIAIDODAM@niaid.nih.gov>Cc: Haskins, Melinda (NIH/NIAID) [E] --------- Subject : Fwd: Thanks and filmingFor discussion. (b) (4). (b) (5) ------------------------Sent from my iPhoneBegin forwarded message:From: Janet Tobias <janet@ikanamed ia.com>Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> -:-:-:.===========--=-=-= Cc: "Robinson, Whitney (N.I.H../_.N;_I.A ID). .:[.C..J:,"_ :_.===~:;;;------- (b)(6) "Barasch,Kimber I y (NIH/NIAID) [C]" CbH6)>Subject: Re: Thanks and filmingJanetSent from my iPhoneOn Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE]--------- CbH > wrote:Just called you . sorry crazy morningCall me a .__ Cb)(6_) they can pull me from a meeting _____Patricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNat ional Institute of Allergy and Infectious DiseasesNIH-002245(b) (4)The National Institutes of Health31 Center Drive, MSC 2520- Room 7A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statement made that are sender 's own and not express ly made on behalf ofthe NIAID by one of its representatives.From: Janet Tobias <janet@ikanamedia.com>Sent: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) ---------------~-=-- CbH6J> Subject: Re: Thanks and film ingPatty can I call you quickly about something-wil l take 3 minutes.Sent from my iPhoneOn Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID)[E] CbH6Jw> rote:It's been super busy. Will group with others tomorrowand get back to you.Sent from my iPhoneOn Jan 30, 2020, at 7:51 PM, Janet Tobias<ianet@ikanamedia .com> wrote :Hi Patty: Thanks for arranging thephone call. CbH4)(b) (4)NIH-002246Never a dull moment in your world!JanetNIH-002247(b) (4)From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 13:58:53 +0000Sylvia BurwellSubject: RE: Travel restriction policyThanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises.It was tough , but we got it right.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Sylvia Burwell (b) (6)Sent: Tuesday, February 4, 2020 8:3-2- A-M- -- ::;..,..-,= To: Fauci, Anthony (NIH/NIAID) [E] CbH6J>Subject: RE: Travel restr iction policyTony,Thanks so much for sending this AND for your very valuable time on Sunday.Our students that returned last week are in self-quarantine ...let me know if I can be helpful to you in any way.Best,SylviaFrom: Fauci, Anthony (NIH/NIAID) [E] ______ Cb_H_6JSent: Monday, February 3, 2020 7:04 PMTo: Sylvia Burwell Cb()6 )Subject : Travel rest riction policyNIH-002248EXTERNAL EMAIL : Use caution with links and attachments.Sylvia:You probably already have this information, but here is the official policy as peour recent discussion (see link).https :// china. usembassy-ch i na .o rg. cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonimm igra nts-bof-persons-who-pose-a-risk-of-transm itti ng-2019-novel-coronavi rus/Best regards ,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .NIH-002249From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 202013:07:15 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: FW: Phone interview request from Seoul, KoreaLet us di scuss.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail Cb) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: The Scoop tbs eFM ------------ (b)(6)Sent : Tuesday, February 4, 2020 6:0-6- -A-M-- -~~ To: Fauci, Anthony (NIH/NIAID) [E)- -------- (b)(6) Cc: (b)(6)Subject: Phone interview request from Seoul, KoreaHello, Dr. Anthony Fauci.This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea.We deliver local and international trend ing news to English speaking listeners around the world .We'd like to invite you to talk with us on the phone for a special interview regarding the novelcoronavirus outbreak.If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturday thiswee k, ORsometime betwee n 9:30 and 10:30 am next Monday, please let us know.And if you're not available for the given time, please also let us know other times feasible for you.The interview will run for about 10 minutes and you'll get your questions in advance.If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated.NIH-002250NIH-002251I look forward to hearing from you soon.Thank you very much .Seyoung LeeFrom:Sent:To:Subject:Attachments :Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 13:05:59 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: 2019-nCoV: potential infection on CD4 cells.Insert positions in HIV gp120.pdfPlease have someone respond to this person.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: (b) (6)Sent: Tuesday, February 4, 2020 2:07 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E)- ------- (b)(6) Subject : 2019-nCoV: potential infection on CD4 cells.Dear Dr. Fauci,As you reali zed the Indian resea rcher published a paper few days ago entitled "Uncann ysimilarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I. gp120 and Gag", whichwas latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL onlinecalcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1 ", "2", and "3"originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on thespike protein of both bat and 20 19 corona virus (page 4 and 6). These insertions are potentialCD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2binding domain (both SARS and 2019 coronavirus targetACE-2, page 5 and 6). In another word,the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cellstoo (like HIV, see page 6) !It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating theirCD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine afterobta ining Spike protein of 20 19-nCoV shall examine its interaction with CD4.NIH-002252Thank you for your immediate attention. Please keep me anonymous.God bless us,NIH-002253(b)(6JFrom:Sent:To:Subject:Francis:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 12:36:50 +0000Collins, Francis (NIH/OD) [E]names for WHO working groupDerek Kan, Acting Deputy Director of 0MB and a member of the President'sCoronavirus Task Force called me last night and in a very nice way said he wouldlike to send me a list of names for consideration to be on the working groups toexamine the evolution of the nCoV. He worked as an executive in biotech priorto joining the USG and knows these individuals well. They are all people that weknow and so I am just passing them on to you for our consideration.Thanks,TonyAnthony S. Fauci, MDDirector(b) (5)National Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX : (301 496-4409E-mail : (b)( 6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the origina l intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its represe ntatives .NIH-002254From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 11:43:36 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: FW: REQUESTF ORA TV INTERVIEWO N WION TV INDIALet us discuss.From: Latika Chugh {WION) <latika.chugh@zeemedia.esselgroup.com>Sent: Tuesday, February 4, 2020 5:15 AMTo: Fauci, Anthony (NIH/NIAID) [E]-------= (b-)c(c-6-)=Cc: Wion Guest Relations <wion.guestrelations@zeemedia.esselgroup.com>Subject: REQUESTF ORA TV INTERVIEWO N WION TV INDIADear Anthony S. Fauci,M.D., NIAID DirectorGreetings from WION!World Is One News (WION)is an international English news channe l from the Zee Med ia Group,Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India',presenting its own perspective on internationa l issues of critical significance. WION is thepreferred channel for most opinion makers across the world as they happily attend our showsbringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia,The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore andSouth Africa etc.WION's shows have featured Indian Political scenario & global leaders speaking on issues facingtheir country and the world in general.I would like to request for your time for an interview with us anytime soon today for 10-15minutes. We usually conduct Interview via Skype. Request you to share your Skype Id.It's regarding CORONAVIRUS.Please let us know when is the best time for you to join us via Skype. Waiting for yourconfirmation.CLICK HERE TO WATCH WION LIVE:https://www .wionews.com/live-tvLive TV, News I wionews.comNIH-002255lNIH-002256© 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved.www .wionews. comLook fo1ward hearing from you .RegardsLatika ChughWION TV , IndiaZee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and isintended for use only by the addressee. Zee Media Corporation Ltd. accepts no responsibility for anymistransmission of, orinterference with, th is communicationFrom:Sent:To :Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 03:02:57 +0000Shalimar AdornoCc:Subject :Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJRE: Message from Dr. Jim Yong KimShalimar:Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due tothe coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied hereand at (b)(6) to squeeze in a time that works for Jim and me. Thank you.Best regards,TonyFrom: Shalimar Adorno (b)(6)Sent : Monday, February 3, 2020 6:33 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)(6) Subject : Message from Dr. Jim Yong KimGood evening Dr. Fauci,I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow.Can you please advise if you have any availability?Kindly,Shalima r AdornoAssistant Vice PresidentGloba l Infrastructure Partners1345 Avenue of the Americas. 30th FloorNew York, NY 10105T (b) (6).___ __ (=b)~(6=)NIH-002257From:Sent:To:Subject:Anthony S. Fauci , MDDirectorFauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 01:14:05 +0000Collins, Francis (NIH/OD) [E]RE: CoronavirusNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)(b) (5)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Collins, Francis (NIH/OD) [E] --------- (b) (6) >Sent : Monday, February 3, 2020 7:26 PM -------~~To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ________ _.Subject: FW: CoronavirusFrom: Shapiro, Neil (NIH/OD) [E] (b)(6)Sent: Monday, February 3, 2020 6:02 PM ------~= To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E]CbH6l;J ohnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz,.....-.-.- :---:---""."':"'"""".""".:--:":===:..--__;--=--=~-Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E](b)(6)Cc: Shaya, Cecile (NIH/OD) [E) --------- (b)(6)Subject: RE: CoronavirusNIH-002258(b) (5)From: Shapiro, Neil (NIH/OD) [E]Sent: Monday, February 3, 2020 4:05 PM-----~~To: Collins, Francis (NIH/OD) IE] (b)( >; Tabak, Lawrence (NIH/OD) [E](b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6)>; Wolinetz,Carrie (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E](b)(6)Cc: Shaya, Cecile (NIH/OD) [E] -------- (b)(6)Subject: RE: Coronavirus(b)(S)From: Collins, Francis (NIH/OD) [E] (bH6J>Sent : Monday, February 3, 2020 1:48 PM -----~~ To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E](bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz,Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E](b)(6)Cc: Shaya, Cecile (NIH/OD) [E) -------- (b)(6)Subject: RE: CoronavirusNIH-002259(b)(5)FCFrom: Shapiro, Neil (NIH/OD) [El Cb)( >Sent: Monday, February 3, 2020 11:33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E]CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz,Carrie (NIH/OD) [E] CbH6)>H; allett, Adrienne (NIH/OD) [E](b)(6)Cc: Shaya, Cecile (NIH/OD) [E]Subject: CoronavirusImportance: HighNeil(b)(6)>NIH-002260(b)(5)From:Sent:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 01:08:37 +0000To: Kai Kupferschm idt ------- --=~ Cc: Greg Folkers (b)(6) ;Billet, Courtney (NIH/NIAID) [E];Conrad,Patricia (NIH/NIAID) [E]Subject: RE: coronavirus quick questionKai:Error in my statement to you. I meant to say that " ...... most t ransmissions occurfrom someone who is symptomatic" - not asymptomatic. I am really tired . Notmuch sleep these days.Best,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Kai Kupferschmidt ---------- (b)(6) Sent: Monday, February 3, 2020 7:37 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------ =--c=Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b~)(':.a; iBillet, Courtney (NIH/NIAID) [E]<billetc@niaid .nih .gov>Subject: Re: coronavirus quick questionThanks Tony,this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imagineyour workload at the moment. I will include comment from you now .BestKaiNIH-002261On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....__ ____ (b_H_6.)> wrote:Sorry that I got to this so late. I have been swamped. I just readyour story in Science. It is unfortunate that they did not interview thepatient. Obviously, this changes the conclusion of the paper. Mycomment: "There1s no doubt after reading [the NEJM] paper thatasymptomatic transmission is occurr ing" was made because there hasbeen a lot of discussion among Chinese investigators thatasymptomatic infection is occurring in Wuhan City and Hubei Province,yet no publication came out and said this. Since th is was the firstpublication supposedly documenting this phenomenon, that is why Ireferred to the paper and made my comment. It is unfortunate thatthis error was published, but it still does not really change anything.Rather than rely on rumors, this evening I telephoned one of mycolleagues in China who is a highly respected infectious diseasesscientist and health official. He said that he is convinced that there isasymptomatic infection and that some asymptomatic people aretransmitting infection . The NEJM paper may be incorrect, butaccording to reputable Chinese scientists , my statement is correct .Having said that, I have been saying for some time that even ifasymptomatic infection occurs, it is very unlikely to be a major driver ofthe outbreak since most transmissions occur from someo ne who isasymptomatic.Best regards,TonyNIH-002262From:Sent:To:Subject :Fauci, Anthony (NIH/NIAID) [E)Tue, 4 Feb 2020 00:37:32 +0000Conrad, Patri cia (NIH/NIAID) [E)RE: Tony and ConronavirusSet up a caLI for me with Ed HenryAnthony S. Fauci , MDDirectorNational Ins titute of Allergy and Infectious Dise asesBuilding 31, Room 7 A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: (b) (6)FAX: (301) 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. Itshould not be used by anyone who is not the original intended recipient. lf you have received this e-mail in eITorplease inform the sender and delete it from your mailbox or any other storage devices. The National Institute ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's ownand not express ly made on behalf of the NlA ID by one of its representatives.-----Original Message-----From: Conrad, Patricia (NIH/NIAID) (E] ---------(b-) (6} Sent: Monday , February 3, 2020 12:28- P-M- ---~~ To: Fauci, Anthony (NlH/NlAID) [E] -------- (b)( 6)> ; Folkers, Greg (NlH/NIAID) (E] (b )( 6)Subject: FW: Tony and Conronavirusf irm for Feb 11ASF will you cancel DDCF or do r need to? Please advisePatricia L ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Infectiou:s Diseases The National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)( 6)30 1-496 -4409 faxDisclaimer:The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. Itshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITorplease inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergyand Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and notexpressly made on behalf of the NIAID by one of its representatives.-----Original Message-----From : Katz , Ruth <Ruth.Kat z@aspenin sti tute.org>Sent: Monday , f ebr1.1a1y3 , 2020 12:20 PMNIH-002263To: Conrad, Patricia (NIH/NWD) [E]- --------- (b)( Cc: Katz, Ruth <Ruth.Katz@aspeninstitute.org>Subject: RE: Tony and ConronavirusWe have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Timewould be over lunch. Attendees arrive around 11 :30 to grab lunch. Program sta rts at noon and runs to about II:15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortlybefore noon so we can mike him up.J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run withit. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first.Our comms team is really interested in pushing this --RuthRUTH J. KATZVice President, Aspen InstituteExecutive Director, Health, Medicine and Society Program The Aspen Instituternth.katz @aspeninstitute .org202-736-5827-----Original Message-----From: Conrad, Patricia (NIH/NTAJD) [E] --------(-b)(-6) > Sent: Monday, February 3, 2020 11 :57 AMTo: Katz, Ruth <Ruth.Katz@aspeninstitute.org>Subject: RE: Tony and ConronavirusTf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pmLet me knowPatricia L. ConradPublic Health Analyst andSpecia l Assistant to the DirectorNational Ins titute of Allergy and Infectious Diseases The National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. Itshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergyand Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and notexpressly made on behalf of the NIA TD by one of its representatives.-----Original Mes:sage-----From: Katz , Ruth <Ruth .Katz@aspenin stitute.org>Sent : Monday , Fcbniary 3, 2020 11: 43 A-M-- ----r:,,:,~ To: Conrad, Patric ia (NIH/N IAID) [E] (b)(6) >Cc: Katz , Ruth <Ruth .Katz@aspeninstitut e.org>NIH-002264Subject: RE: Tony and CoruonavirusHi Patty,Thanks :so much and understand comple tely. Can only imagine how crazt::<ly ou all must be.Definitely don't want to do this without Tony. Jf next week doesn ' t work , please send some potential options.Getting a room can be the real challenge here. So I'd like to at least reserve space and cance l if need be. Also tryingto coordinat e with Ron Klain who is very eager to participat e.Let me know ifI shou ld definitely cance l our space for February 11 or continue to hold for now.Thanks again for everything!RuthRUTH J. KATZVice President, Aspen InstituteExec utive Directo r, Health, Medicine and Society Program The Aspen Instituternth.katz @aspeninstitute.org202-736-5827-----Original Message-----From: Conrad , Patricia (NIH/NTAJD)[ E]- --------(b-)(l>t Sent: Monday , Feb ruary 3, 2020 11 :36 AMTo: Katz, Ruth <Ruth.Katz @aspeninstitute.org >Subject: RE: Tony and ConronavirusHi Ruth - circling back - hope we can make this work - will get back to you in a day or two ....Patr icia L. ConradPublic Health Analyst andSpecia l Assistant to the Dir ectorNational l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. Itshould not be used by anyone who is not the original intended recip ient. If you have received this e-mail in errorplease inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergyand Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and notexpressly made on behalf of the NlAlD by one of its representatives.----- Original Message- ----From: Conrad , Patricia (NlH/NIAID) [E]Sent: Monday , Feb ruary 3, 2020 8:40 AMTo: Katz , Ruth <Ruth .Katz@aspeninstitute.org >Subject: RE: Tony and ConronavirusHi - sorry for the delay - its been insane ly busy.NIH-002265He would love to do this but our schedu le has been changing literally by the minute - so much so that we have hadto cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to dothis and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit.Defer to you tho as to when you want to do your event. Happy to chat more ....Patricia L. ConradPublic Health Analyst andSpecial Assistant to the Dir ectorNational Institu te of Allergy and Infectious Diseases The National Inst itutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. Itshould not be used by anyone who is not the original intended recip ient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergyand Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender 's own and notexpressly made on behalf of the NlAlD by one of its represen tatives.-----Original Message-----From: Katz , Ruth <Ruth.Katz @aspenin stitute.org >Sent: Friday , January 31 , 2020 5:33 PM- -------~~ To: Conrad , Patric ia (NIH/NTAID} [E] ---------(b-)(6} Cc: Katz , Ruth <Ruth.Katz @aspenin stitute.org>Subject: Re: Tony and ConronavimsHi Patty,Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room.Thank s so much. Hope all is well -RuthSent from my iPhoneOn Jan 27, 2020, at 2:45 PM, Conrad, Patricia (NIH/NIAID) [E]---------------------- (b) ( >> wrote:Hi ruth - will get back to you as soon as we canPatricia L. ConradPublic Health Ana lyst andSpecia l Assistant to the DirectorNational Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health31 Center Drive , MSC 2520 - Room 7A03Bethesda, Maryland 20892(b)(6)301-496 -4409 faxNIH-002266Disclaimer:The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. ltshould not be used by anyone who is not the original intended recip ient. If you have receiv ed this e-mail in errorplease inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergyand Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and notexpressly made on behalf of the NIA ID by one of its represen tat ives.From: Katz , Ruth <Ruth .Katz@aspe ninstitute.org <rnai Ito: Ruth.Katz @aspeninst itute.org >>Sent : Monday , January 27, 2020 4:25 P-M- ------------------~~= To: Comad , Patri cia (NIH/NIAID) [E] __________________ Cb _H_6)Cc: Katz, Ruth <Ruth.Kat z@aspen insti tute .org<mailto:Ruth.Katz @aspen institu te.org>>Subject: Tony and ConronavirusHi Pat ty,Hope all is well and that your 2020 is off to a good, if no doubt, busy start.Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vitiesat the Institute. Hope you can be of help again.1 would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices -hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, formerObama Ebo la czar -- is availab le -- and hope Tony might be as well. Tony and Ron are my first two choices.Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in thelineup .Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance?As always, many thanks -All best ,RuthRUTH J. KATZVice President, Aspen InstituteExecu tive Director, Health , Medicine and Society Program The Aspen Instituteruth.katz @aspeninstin1te.org <mailto:ruth.katz @aspen insti tute.org >202-736-5827NIH-002267From:Sent:To:Cc:Subject :Kai:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 00:29:06 +0000GKraei gK uFpoflekersrc~--h m--id--t ---------=---:(b-)(6=) ;B-illet, Courtney (NIH/NIAID) [E] RE; coronavirus quick questionSorry that I got to this so late. I have been swamped. I just read your story inScience. It is unfortunate that they did not interview the patient. Obviously, t hischanges the conclusion of the paper. My comment: "There's no doubt afterreading [the NEJM] paper that asymptomatic transmission is occurring" was madebecause there has been a lot of discussion among Chinese investigators thatasymptomatic infection is occurring in Wuhan City and Hubei Province, yet nopub licat ion came out and said this . Since this was the first publicationsupposedly document ing this phenomenon , that is why I referred to the paperand made my comment. It is unfortunate that this error was published , but it stilldoes not really change anything. Rather than rely on rumors, this evening Itelephoned one of my colleagues in China who is a highly respected infectiousdiseases scientist and health official. He said that he is convinced that there isasymptomatic infection and that some asymptomatic people are transmittinginfection . The NEJM paper may be incorrect , but according to reputab le Chinesescientists, my statement is correct. Having said that , I have been saying for sometime that even if asymptomatic infection occurs, it is very unlikely to be a majordriver of the outbreak since most transmi ssions occur from someone who isasymptomatic.Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone : Cb()6 )FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notNIH-002268accept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Kai Kupferschmidt ------------ (b)(6) Sent: Monday, February 3, 2020 11:47 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E]- ------- CbH6J> Subject : coronavirus quick questionTony,do you have 5 minutes for a quick phone call? Writing a story about the German paper claiming anasymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, soreally wanted to get your reaction on this.CheersKaiKai Kupferschmidtcontributing correspondent "Science"(b)(6)(b)(t wit t er: @kakapeNIH-002269From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 22:28:34 +0000Billet, Courtney (NIH/NIAID) [E]Subject: FW: Coronavirus - reporter 's questionsNIAID in quir ies, please.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Rob Britt Cb) (6)Se nt: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E)-- -----------~-~ CbH6)> Subject : Coronavirus - reporter's quest ionsHi Dr. Fauci: We are updat ing our coronavirus story periodically, keeping it factual and level-headed, andI have seen your comment s on NPR Friday and in the NV Times ove r the weekend, so I hope you couldcomment very briefly for our story :-- What's your expectation fo r whether this will become a pandemic?-- Pandemic does not necessarily equate to a terrible situat ion, comp ared to , say bad flu seasons. What 'syour expectation on the pote ntial severity of t his coronavirus?-- And your suggestion to people in the U.S. who might be very concerned?Thanks for any help you can provide.Cheers,RobRobert Roy BrittTop Write r on Medium in Science & Health.Contr ibutor to OneZero (science) & Elemental (health).Former editor-in -chief of Live Science and Space.com.NIH-002270(b)(6)(b)(6)NIH-002271From:Sent :To:Cc:Subject:Seth:Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 22:27:31 +0000Seth LedermanErbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E]RE: New NHP data on our vaccine for smallpox & monkeypoxI am swamped with coronavirus stuf f, and so I am forwarding this to EmilyErbelding to take a look and respond. Thanks.Best regard s,TonyAnthony S. Fauci , MDDirecto rNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may conta in sensitiveinformat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Seth Lederman (b)(6)> ------------- Sent : Friday, January 31, 2020 11:05 AM To: Fauci, Anthony (NIH/NIAID) [E]-- ----------~-~- -- (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypoxDear Tony,I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger.I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented aposter on our further work with TNX-801 (horsepox) as a potent ial vaccine for smallpox andmonkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (nolesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, butlesions on 2/3 animals. More complete information is on the poster attached, which is available on ourwebsite at (https ://conten t .eguisolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/detail/118 6).NIH-002272-We'd welcome the opportunity to discuss the data with you and your team.Best, SethSeth Lederman , MD I Chief Executive OfficerTonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP509 Madison Avenue . Suite 1608, New York, NY 10022Tel ___ _.hl@ I Fax 212 923 5700--------- -'-'""I w"w=w .T o nixPharma.cornNIH-002273(b)(4)(b) (4)From:Sent:To:Cc:Subject:Danielle:Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 22:21:41 +0000Steinberg, DanielleConrad, Patricia (NIH/NIAID) [E);Billet , Courtney (NIH/NIAID) [E)RE: PBS Nature inquiry about CoronavirusMany coronaviruses exist in animal reservoirs, particularly in bats. Rememberthat for the SARS outbreak in 2002, bats infected palm civet cats who were sold inlive/wet markets and the civet cats spread the virus to human . Same for MERS -bats to camels to humans. You ask that there have been animal markets for along time, and so why now. The fact is that this is likely pure chance+/- moreinteractions in the human-animal interface . Animal viruses mutate and most ofthe time the mutations have no significant impact on virus transmission tohumans . Sometimes they mutate and allow single "dead end" transmissions toindividual humans with no efficiency in going human to human and so we getindividual infections and no outbreak as we have seen with HSNl and H7N9influenzas that jump from chickens to humans but do not go from human tohuman. And then rarely, animal viruses mutate and the mutat ion allows themnot only to jump species to humans, but to also efficiently spread from human tohuman . That is what we saw in SARS and now we see this with 2019-nCoV, whichseems to have adapted itself very well to human to human transmission, as perwhat is happening in China.I hope that this is helpful.Best regards,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .NIH-002274From: Steinberg, Danie lle <SteinbergD@th irteen.org>Sent : Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E- _-_-_-_-_- ~~ CbC)6)>Subject: PBS Nature inquiry about CoronavirusHi Dr. Fauci,Hari Sreenivasan of PBS NewsHour suggested I reach out to you with a specific nature question thatwe're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy!We're wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, Chinahas been using animal markets/wildlife trade in these exact ways for a while, so what changed or isdifferent now to cause this illness and outbreak? Any other information you can provide on how animalsare involved wo uld be greatly appreciated.Thank you !Best,Danielle SteinbergDanielle Steinberg I Digital Lead, NATURE I +1 (212) 560-3049 (office)I l I 825 Eighth Avenue 14th Fl. I New York, NY 10019-7435pbs.orq/nature I Facebook I Twitter I lnstagram I YouTubeNIH-002275From:Sent:To:Cc:Subject :Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 16:43:08 +0000Conrad, Patricia (NIH/NIAID) [E)Barasch, Kimberly (NIH/NIAID) [C)FW: Bloomberg Radio 2/4This is Bloomberg and so if we can do this, let us try. If it is too much of a hasslethen say sorry no . Thanks.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: (b) (6)FAX : (301 496-4409E-mail (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) <jrobinson158@bloomberg .net >Sent: Monday, February 3, 2020 11:23 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)Subject: Bloomberg Radio 2/4Hi Dr. Fauci!I Hope this email finds you well. I'm emailing to see if you can join Tom Keene,Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning asa PH ONER at 8:00am or 8: 15am Et to discuss the Coronavirus. Please let me know ifwe can make this happen. Many thanks!-JameelahJameelah Robinson, M.S.Bloomberg SurveillanceTelevision & RadioBloomberg TV is the world's most-watched business news network, available in morethan 360 million homes worldwide . Watch us live on our website, smartphones, iPadNIH-002276NIH-002277app and the Bloomberg Professional Service.http://Bloombe rg.com/tv/Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), SanFrancisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You canhear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, andTune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audioFrom:Sent:Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 15:17:23 +0000To:(NIH/NIAID) [E]Subject:Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, HughRE: Wuhan nCoV InhibitorsLoren:Thanks for t he note.Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail: (b)(6)(b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who Is not the original Intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Walensky, Loren D.,M.D .,Ph .D. ------------- (b)(6)Sent : Sunday, Februa ry 2, 2020 11:28 PM ------------ -.a-s-= To: Glim cher, Laurie,M .D. (b)(6J>; Fauci, Anthony (NIH/NIAID) [El-------- (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] ----------- (b)(6) Subj ect : RE: Wuhan nCoV InhibitorsNIH-002278(b) (4)PS; Dr. Fauci, ------------------------ (b)(6)Thank you again for any guidance you can provide so that we can try to be of help.Best,LorenLoren D. Walensky, M.D., Ph.D.Professor of PediatricsPrincipal Investigator , Linde Program in Cancer Chemical BiologyAttending Physician in Pediatric OncologyDirector, Harvard/MIT MD-PhD ProgramDana-Farber Cancer Institute/ Harvard Medical School450 Brookline Avenue, LC3216Boston, MA 02215Office: (b) (6)Fax: 617-582-8240Email; (b)(6)Twitter: (b)(6) ------From: Glimcher, Laurie,M.D . --------------- (b)(6) Se nt: Sunday, February 2, 2020 9:33 PMTo: Anthony (NIH/NIAID) Fauci---------,.- (b.H--=6. ) Hugh Jr Auchincloss(b)(6)Cc: Walensky, Loren D.,M.D.,Ph.D.- ------------- (b)(6) Subject: Fwd: Wuhan nCoV InhibitorsTony and Hugh,Loren Walensky is a superb physician -scientist at Dana-Farber -----------------If this is of interest to you, please let me know or contac t him directly.Many thanks,LaurieLaurie H. Glimcher, M.D.President and CEONIH-002279(b)(4)Dana-Farber Cancer Inst ituteRichard and Susan SmithProfessor of MedicineHarvard Medical School450 Brookline Avenue, Dana 1628Boston, MA 02215) §) tel.617.632.2161 faxBegin forwarded message:From: "Walensky , Loren D.,M.D.,Ph.D."Subject: Wuhan nCoV InhibitorsDate : January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." ------------------------------- (b~)(6J=>Hi Laurie. I hope all is well on your end .NIH-002280(b)(6)>(b) (4)(b) (4)Thanks so much,LorenLoren D. Walensky, M.D., Ph.D.Professor of PediatricsPrincipal Investigator, Linde Program in Cancer Chemical BiologyAttending Physician in Pediatric OncologyDirector, Harvard/MIT MD-PhD ProgramDana-Farber Cancer Inst itute/ Harvard Medical School450 Brookline Avenue, LC3216Boston, MA 02215Office: (b) (6)Fax: 617-582-8240Email: (b)(6) ------------ ·The information in this e-ma il is intended only for the person to whom it isaddressed. If you believe this e-mail was sent to you in en-or and the e-ma ilcontains patient informa tion , please contact the Partn ers Compliance HelpLine athttp ://www.partners .org/compli anceline . If the e-mail was sent to you in errorbut does not contain patient info1mation, please contact the sender and properlydispose of the e-mail.NIH-002281(b) (4)From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAID) [E)Mon , 3 Feb 2020 15:12:39 +0000Routh, Jennifer (NIH/NIAID) [ElConrad, Patricia (NIH/NIAID) [ElFW: ANSA news agencyPlease get someone to provide answers for me to send to this person. I do nothave time to do it myself ,Anthony s. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Battifoglia Enrica <Enrica.Battifoglia@ansa.it>Sent : Monday, February 3, 2020 5:37 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6)Subject : ANSA news agencyDear Professor Fauci,I am Enrica Battifoglia of the Italian news agency AN SA, I already have had the pleasure tointervi ew you several times at the AIDS world conferences.I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on theANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Italywith over 1.5M contacts each month. I am sure that your clarity and comp etence will be highlyvaluable to put some much-needed order among so many contrasting news and data, and wouldbe much appreciated by our reader s.NIH-002282NIH-0022831) Do the current available data allow to understand the threat level of coronarivus 2019-nCo Vin terms of both lethality and diffusion speed, and about the possible evolution scenarios of thedisease?2) What exactly we know about its modes of transmission, especially from people who do notyet have the symptoms?3) Are the genetic sequences provided by China enough to start working on a vaccine?What are the technical times to develop a working vaccine in terms of scientific research, andwhat are the approx times for the necessary legal certifications, and for industrial production anddistribution?4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in thelast 20 years and in 2009 the virus responsible for the flu pandemic too did come from China:what sort of preventive measures could be practicable to reduce the risk ofrepetition of theseevents?Thank you so much for your time your attention!Kindest RegardsEnrica BattifogliaScience and Technology Head EditorANSA News AgencyII contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono doconsiderarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei DotiPersonali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa emailin mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di nonNIH-002284diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mailappartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA.The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to beconsidered as confidential and protected under the Regulation EU 2016/679 (GDPR), General Data Protection Regulation, aswell as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail inthe absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it,inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone andmay not necessarily reflect those of ANSA AGENCY.From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 15:10:32 +0000Joe PalcaSubject: RE: Coronavirus vaccineJoe:Thanks for the note. The has nothing to do with the validity of the test. We seethis with other viruses when you look at shedding. When there is a low titer ofvirus, any specific site (in this case a nose or throat swab) may vary betweenpositive and negative even though the person is clearly still infected . It could bethat the virus is there in the throat at one point and cleared at another and comesback again. Alternatively, it may be that the virus is always there, but at differenttiters and at some points it is present below the sensitivity of the test, eventhough the test is in general quite sensitive.Hope that this is helpful.Best regard s,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520Nation al Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301) 496-4409E-mail (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Joe Palca <JPalca@npr.org>Sent: Monday, February 3, 2020 9:3-0- -A-M-~ ~ To: Fauci, Anth ony (NIH/NIAID) [E)- ------ (b)( > Subject : FW: Coronav irus vaccineFrom: Joe Pa leaSent: Monday, February 3, 2020 9:13 AMNIH-002285To: 'anthony.facui@nih.gov ' (b)(6)>Cc: 'Deatrick, Elizabeth (NIH/:N-:'.-I"A-.:"1--0::--): -:[-C:'.]",:~"=. ===-----= (b")'"~"( >; Scott Hensley(b)(6)Subject: RE: Coronavirus vaccineHi Tony,It's been nice hearing you on the various press conferences ... can't believe we're still both doing this.Have a question about something Redfield said in Friday in the White House briefing about nCoV. Hesaid using their PCR assay, the virus can be detectable one day, then not the next, then detectab le.I'm curious about this . I see a few possibilities:1. The test isn't as sensitive as CDC hopes2. The sample was taken from different places3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next.4. The virus may be hanging out in the terminal bronchioles, and only pop up to the upperrespiratory system from time to time.Arn I on the right track? Wou ld you have a few minutes today to record an interview with me?JoeNIH-002286From:Sent:To:(b)(6)Mon, 3 Feb 2020 05:45:35 -0500Conrad, Patricia (NIH/NIAID) [E)Subject : Fwd: Interview request (Seoul, Korea)Sent from my iPhoneBeg in forwa rded message:From: ;;'<} ~ '-t (b)(6) >Dat e: February 3, 2020 at 2:29:21 AM EST To: "Fauci, Anthony (NIH/NJAID) [E]' ----------------'=""'("bH"6l '>= Subject: Interview request (Seoul, Korea)Dear Or. Fauc i.I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea.I am the directo r of currunt- issue radio show of TBS and I'd like to have a telephoneinterview with you on my radio program about co ronavirus issue all over the wor ld.As Korea is a very close count·y to China and many people are very concerned aboutthis issue.I would like to hear your opinion as a world authority on this issue.The time for phone interview would be about 6 a.m . at Maryland time and I want toproceed it through an English-Korean interp reter.I would apprec iate it if you could reply to me if you are poss ible.The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim.Respectf ully,Mrs. Hyun- na Cha(b)(6)TBS. Seoul. KoreaNIH-002287From:Sent:To:Subject :Fauci, Anthony (NIH/NIAID) [E)Mon, 3 Feb 2020 03:47:33 +0000Howard SchatzRE: If too busy then pass---l'd understandToo soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than weare now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the samefamily of viruses as SARS.-----Original Message-----From: Howard Schatz ----------- (b~)~(=Sent: Friday , January 31, 2020 8:51 AMTo: Fauci . Anthony (NIH/NIAID) [E] ------ =CsHb-=-6.),Subject: If too busy then pass---T'd understandTony,New Coronavirus: saw you on national news with a dozen others at DT's table yesterday.Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others.What is your cunent thinking on it?Hope all is well, otherwi se.Thanks ,howardNIH-002288From :Sent :To:Subject :Fauci, Anthony (NIH/NIAIO) [E)Mon, 3 Feb 2020 03:45:59 +0000Auchincloss, Hugh (NIH/NIAID) [E]FW: Wuhan nCoV InhibitorsPlease handle this . Thanks .From: Glimcher, Laurie,M.D. -------------- (b)( > Sent: Sunday, February 2, 2020 9:33 PMTo: Fauci, Anthony {NIH/NIAID) [E] ------ (=b)c-(c= >; Auchinclo ss, Hugh (NIH/N IAID) [ E](b)(Cc: Walensky , Loren D.,M .D.,Ph.D. --------------- (b)(6)Subject : Fwd: Wuhan nCoV InhibitorsTony and Hugh,(b)( 4Loren Walensky is a superb physician-scientist at Dana-Farber -----------------If th is is of interest to you, please let me know or contact him directly .Many thanks,LaurieLaur ie H. Glimcher , M.D.President and CEODana-Farber Cancer InstituteRichard and Susan SmithProfessor of MedicineHarvard Medical School450 Brookline Avenue, Dana 1628Boston, MA 02215"--- ~~ @.!.! te l.617.632.2161 faxBegin forwarded message:From: "Wa lensky, Loren D.,M.D.,Ph.D." ------------- (b)(6)> Subject : Wuhan nCoV InhibitorsDate : January 30, 2020 at 7:23:54 PM EST ------------- r;a-.-,--.= To: "Glimcher, Laurie,M.D." --------------- (b)(6)NIH-002289Hi Laurie. I hope all is we ll on your end .Thanks so much,LorenLoren D. Walensky, M.D., Ph.D.Professor of PediatricsPrincipal Investigator, Linde Program in Cancer Chemical BiologyAttending Physician in Pediatric OncologyDirector, Harvard/MIT MD-PhD ProgramDana-Farber Cancer Institute/ Harvard Med ical School450 Brookline Avenue, LC3216Boston, MA 02215Office: (b)(6)Fax: 617-582-8240Email (b)(6)NIH-002290(b) (4)(b) (4)NIH-002291The information in this e-mail is intended only for the person to whom it isaddressed. If you believe this e-ma il was sent to you in error and the e-mailcontains patient information, please contact the Partners Compliance HelpLine athttp: //www .partners .org/complianceline . If the e-mail was sent to you in errorbut does not contain patient information, please contact the sender and properlydispose of the e-mail.From:Sent :To:Subject :Please handle.From: Ulrica MolstadFauci, Anthony (NIH/NIAID) [ElMon, 3 Feb 2020 02:10:49 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: Homozygous for Alpha-1 antitrypsin and coronavirus?(b)(6)> ----------- Sent : Sunday, February 2, 2020 9:07 PM To: Fauci, Anthony _{.N:_IH_/N:,IA__I D_) :.[E..]; -:,-_-.-:J-=-=~=~~= ---(-b)(6)>Cc : Ulrica Molstad _________ C_)b_C_6>)Subject: Homozygous for Alpha-1 antitrypsin and coronavirus?H·I1.I read that you are an expert working for NIAID and that you got interviewed about treatments for thecorona viru s.I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted toshare a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS)with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha-1 anti trypsin is an acute phase reactant and increases in sick people. I have seen that the Alpha-1-antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, eventhought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level ofAlpha-1 antitrypsin is misleading and can result in the physician believing that there is nothing wrongwith the patients function of Alpha-1-antitrypsin.I also guess that critically ill ECMO-treated patients with lung symptoms might benefit from receivingAlpha-1 anti protease inhibitor in addition to other medications given to them. What do you think?I believe that this information can contribute in understanding why some supposedly healthy individualsgets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read .Best regards, Ulrica Molstad, M.D.NIH-002292From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon, 3 Feb 2020 00:50:43 +0000James KrellensteinSubject: RE: 2019-nCoV Testing for Public Health LabsJames:Thanks for the heads-up. I will see what I can do.Best,TonyFrom: James Krellenstein ---------- (b)(6) Sent : Sunday, February 2, 2020 7:37 PMTo: Fauci, Anthony (NIH/NIAID) [E) --------. ~Cc: David Barr (b)(6) >; Lord, Aaron (b)(6)Peter Staley ------====~~----- ------------- (b )( 6)Subject: 2019-nCoV Testing for Public Health LabsTony:I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests fromleaders of public health departments and public health practitioners to begin publicly pressuringCDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can performreal time reverse transcription PCR (qRT-PCR) testing for 2019 Novel-Coronavirus (2019-nCoV).Our understanding is that given the public health emergency decla red by HHS, an emergency useauthorization (EUA) from the FDA is required for public health labs to perform their own lab developedtest for 2019-nCoV, even if it is using the CDC's published qRT-PCR protocol and primer/probesequences (htt ps://www .cdc.gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r-detect ion- i nstr uctions . pdf ), and the lab is capable of handling BSL3+ samples.We understand the extreme delicateness of this situa t ion, and also that it is outside of our normalwheelhouse . But given the concerns of our colleagues in the public health sector, we thought it wasimportant to give you a heads up regarding this request .Let us know if there is anyway we can help .Sincerely,James KrellensteinData, Science and Policy CommitteeThe PrEP4AII Collaboration109 S 5th St, Brooklyn, NY 11249(b)(6)NIH-002293James B. Krellensteinhe - him - his(b)(6)(Sent from a mobile device)NIH-002294From:Sent:To:Fauci, Anthony (NIH/NIAID) [E)Sun, 2 Feb 2020 23:54:27 +0000NIAIDODAMSubject:coronavirusAttachments:FW: Invitation for an expert panel webinar on the role of micronutrients and2020.02.02 Expert panel objectives.docxLet us discuss. Probably no.From: (b)(6)> --------------------- Sent: Sunday, February 2, 2020 9:49- A-M- ---,;-. = To: Fauci, Anthony (N IH/NIAID) [E] (b)(6)1>Cc: Peter van-Dael .,,;.__.;. .;...;;...;,_.=== (cb:)":=('6=);'----Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirusDear Dr. Fanci,I would like to address you for an expert panel webinar on the role of micronutrients andcorona virusDue to the new coronavirus outbreak and the rapidly escalating global spread, lots of questionsare raised regarding the role of micronutrients in supporting the immune system. DSM hasreached out to me with a request to organize rapidly a focused expert panel in order toestab lish expert guida nce summarizing key points with respect to the role of micronutrients insupporting our body 's immune response, in light of the current genera l consciousness thatamong other factors nutrition is important in combatting infectious diseases. Peter Van Dael,head of Nutrition Science & Advocacy, is responsible for the coordination of this activity atDSM.I agreed to take on this challenge and therefore intend to organize this expert panel throughwebinar in order to manage the challenges related to busy agendas and travel within the nextweek, if possible. The webinar is expected to last for about 3 hours maxinmm and would befacilitate through the distribution of a short background document I will share in order tofacilitate the discussion.J will try to reach out to you tomorrow by phone in order to review whethe r you would beavailable for this engagemen t and whether you would you have potentia l questions prior toagree ing to participate.With our best regards,Manfred PeterNIH-002295Dr. Manfred EggersdorferProfessor for Healthy Ageing(b)(6)(b)(6)Dr. Peter Van DaelDSM Nutr ition Science & AdvocacyNIH-002296From:Sent:To:(b)(6)Sun, 2 Feb 2020 18:20:17 -0500Carlos del RioSubject:virusRe: [External] RE: Mexican researchers have defined the structure of the CoronaVery inte resting.On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote:(b)(6) sent me this update. Thought you would enjoy. --------- Interesting to see how they view outbreaks .....Coronavirus new s over the weekend was a sma ll net positive (although there wereplenty of nega tives). Encouragingly, doctors appear to be having some successtreating patients with existing antiviral drugs - GILD's remdesivir improved theclinica l con dit ions of a coronavirus patien t in Washington state (WSJ) whileThailand said it had achieved good results using antiviral drugs originally designedfor the flu and HIV (Bloomberg). It's way too early to tell whether these drugs willperfom1 well in other patients (and a vaccine is still some time away) , but theprogress noted in the US and Thail and is positive. The PBOC said it would injectCNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth lywhen they reopen from the New Year holiday (this works out to about CNY150B ofnet incremental liquidity given CNY1.05 T of reverse reports are set to mature onMonday). The gov' t also announced other steps (including waiving equityownership limits for some insurers) aimed to bolstering market confidence . Theglobal corona virus case count cont inues to rise (it now stands at ~ 15K as of Sundaymorning withe death toll north of 300) whi le more travel restrictions are beingimpo sed by governments and companies around the world (Apple said it wouldshutte r all its stores and offices in China until Feb 9). According to a CNBC update ,areas of China responsible for ~80% of GDP and ~90% of exports are set to stayclosed until at least Feb 10.Carlos del Rio, MD.Sent from my iPhoneOn Feb 1, 2020, at 11: 13 PM, Fauci , Anthony (NIH/NIAID) [E]-------- (b) (6)>wrote:I love it! □□NIH-002297-----Original Message----- From: Del Rio, Carlos 4- -----~~ Cb>~<>Sent: Friday, January 31, 2020 10:05 AM ------ --=-= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: Mexican researchers have defined the structure of the CoronavirusThis e-mail message (including any attachments) is for the sole use ofthe intended recipient(s) and may contain confidential and privilegedinformation. If the reader of this message is not the intended recipient ,you are hereby notified that any dissemination, distribution or copyingof this message (including any attachments) is strictly prohibited.If you have received this message in error, please contact the senderby reply e-mail message and destroy all copies of the original message(including attachments).NIH-002298From:Sent:To:Subject :Fauci, Anthony (NIH/NIAID) [ElSun, 2 Feb 2020 22:56:05 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: coronavirusFrom: Dr.h.c. Richard Hajdu ------- (b)( >Sent: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----------~-~-- (b)(6) Subje ct: coronavirusDear Anthony Fauci.I speak hard English so I write to you using google trans lator .I have a cured corona virus cure. I am will ing to provide you . In laboratory conditions you can t ry. Thismedicine can destroy the virus within 12 hours .If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the CzechRepublic. In the city of Brno.Dr. Richard HajduNIH-002299From: Fauci, Anthony (NIH/NIAID) [ElSent : Sun, 2 Feb 2020 22:43:15 +0000To: Cassetti, Cristina (NIH/NIAID) [ElSubject : FW: coronavirus - easy, safe, and likely highly effective treatment.Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf,published article on ozone and ebola 3578-10714-4-PB.pdfPlease handle.From: Robert Jay Rowen (b)( >Sent : Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------- ~(b~)(6) > Subject: coronavirus - easy, safe, and likely highly effective trea tment.Dear Dr. Fauci,I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patientswith coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears.The therapy is ozone. It can be performed, depending on the method, for mere pennies in mater ials. It isnot patentable, so, it lacks profitability needed for some payback for the basic research to get it"approved" .It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5recovered almost immed iately. No sequela. No one has repo rted anyth ing like that.I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed mypractice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, Irecent ly published, might be the solution the world desperately needs for the emerging crisis inresistant infections.I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done toaddress corona virus, which I am try ing to get published. It is not easy. The medical world is vested inPharmaceuticals.I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for thatreason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I amcoming to you about t his as one physicist came to President Roosevelt about harnessing the power ofthe atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you.The first file is a word document I am seeking to get published. Usually, an author will holdup on making material like this public until he get published. However, wi th livesimmediately on the line, we want to alert people that the does exist an available veryinexpensive and extremely safe medical treatment for this and other infections .If you have questions, please contact me here.Sincerely,NIH-002300Robert Ja Rowen , MD(b)(6)www.DrRowenDrSu .comhttp://www . youtube. com/user/Robe rtRowenMDhttps:/ /www.facebook.com/D rRobertJRowen"The doctor of the future will no longer treat the human frame with drugs, but rather willcure and prevent disease with nutrition" , Thomas EdisonHIPAA Notification : This electronic message (includ ing any attachments) isintended only for the exclusive use of the individual to whom it is addressed. This email,including any attachments , is confidential and is legally privileged. If you have receivedit in error please advise the sender immediately by return email and then delete it fromyour system. The unauthorized use, distribution, copying or alterations of this email isstrictly forbidden. If you need assistance please contac (b)(6) Note toPatients : There are inherent confidentiality risks in communicating by email. Whilesafeguards are in place to ensure your privacy, you should not use emailcommunication if you are concerned about any breaches of privacy thatmight inadvertently occur.NIH-002301From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAIO) [ElSun, 2 Feb 2020 22:40:07 +0000Greg Folkers (b)(6))Conrad, Patricia (NIH/NIAID) [ElFW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5FSee below the link that CbH6>senmt e. It is a picture of me briefing President Reagan at the NIHin 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks.From: (b)(6) {N IH/CC/BEP) [El (b)(6)Sent : Sunday, February 2, 2020 5:11 PM ------ ..---.-.-= To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)Subject : RE: Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSFThe oldest one in the batch:https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald-w-reaganand-news-photo/50454084 ?ad ppopup=trueFrom: Fauci, Anthony (NIH/N IAID) [El CbH >Sent : Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6)Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5FfyiFrom: Folkers, Greg {NIH/NIAID) [El --------- (b)(6)Sent: Saturday, February 1, 2020 9:02 PMTo: NIAID OD AM <NIAIDODAM@niaid.n ih.gov>Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5FNIH-002302NIH-002303Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily representmy views nor those of NIAJD , NIH , HHS , or the U.S. government.From: Fauci, Anthony (NIH/NIAIO) [ElSent : Sun, 2 Feb 2020 22:36:41 +0000To: Routh, Jennifer (NIH/NIAID) [E]Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg(NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E]Subject: RE: Fauci/Redfield op-ed for reviewAttachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HMGF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120_EOCCleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docxI have gone over the document and have made a numbe r of t racked changes. In addition, forease of reading I have accepted all the tracked changes and am sending a clean copy. Hencethere are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting allchanges. Please note that the CDC has not announced the 3 additional cases and so dependingon when this goes out we need to make sure that the offic ial number is 11 and not st ill8Thanks !From: Routh, Jennifer (NIH/N IAID) [E] CbHSent: Sunday, February 2, 2020 4 :36 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>S; tover, Kathy (NIH/NIAID) [El(b)(6) >; Folkers, Greg {NIH/NIAID) [El CbH6)>; Conrad, Patricia(NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>Subject: Fauci/Redfie ld op-ed for reviewDr. Fauci -Attached is the draft op-ed for your review. Greg, Hilary and I have added proposed edits in trackchanges. We will send back to CDC/HHS one document with all NIAID edits in track changes. HHS wouldlike to get a draft to the White House at some point this evening.Thanks,JenJennifer Routh [E]News and Science Writing BranchOffice of Communications and Government RelationsNational Institute of Allergy and Infectious Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda, MD 20892Direct (b) (6)Disc laimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not beused by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives.NIH-002304From:Sent :To:Subject:Please handle.Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 19:24:26 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: Specific Questions About CoronaVirusFrom: Rafael C. R. (b) (6)>Sent : Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] ---------------- (.b)-(6-) --..-.= Subject : Specific Questions About CoronaVirusHi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you somemonths ago about the influenza virus differences across regions. I recently t raveled to DC and NY andhad a great time there (before the Corona Virus outbreak)I have some specific questions about the new Corona Virus, and would be very grateful if you cananswer them :1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virusbehavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=OI've used exponential tr end, although it seems to be spreading slower than the expected, I'd like toknow if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spreadexponentially?2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 .Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get preparedfor the worst? Buy water, dry food , stay indoors, withdraw money, etc?Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you,so it means a lot to meThank you,RafaelNIH-002305From:Sent:To:Cc:Subject :Fauci, Anthony (NIH/NIAI0) [E)Sun, 2 Feb 202018:33:43 +0000Liang, Jake (NIH/NIDDK) [E)Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C]RE: FavorThank s, Jake. Mark will contact you directly .From: Liang, Jake (NIH/NIDDK) [E] _______ Cb _>C6bSent: Sunday, February 2, 2020 1:32 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)_C_c_: Mark ..D...y.b;.u_l- ===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E)--------- (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject : Re: FavorHi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clearsome time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear whatthey have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic(not sure whether it is qualified as one yet; if not, pretty close)!! JakeFrom: Anthony Fauci (b)(6)Date: Sunday, February 2, 2020 at 12:20 PMTo: Jake Liang CbH6>>Cc: Mark Dybul CbH6>>",C onrad, Patricia (NIH/NIAID) [E)"----------- CbH6>",B arasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: FavorJake:Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is theformer Head of PEPFAR and the former Director of the Global Fund to Fight AIDS, TB, andMalaria will be at the NIH tomorrow with a scientist who has some very interesting data onhepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Isthere any chance that you can meet with them briefly tomorrow. I believe that you might beinterested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail youto see if you can make this happen. Many thanks.Best regards,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520NIH-002306Phone : (b) (6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .NIH-002307From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 18:02:22 +0000Billet, Courtney (NIH/NIAID) [E]Subject: RE: Seeking comment on Indian paper about new CoronavirusGeeeezFrom: Billet, Courtney (NIH/NIAID) [E] --------- (b)(6)Se nt: Sunday, February 2, 2020 12:53 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------ -(=b-)c(-c6-)=Cc: Marston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E](b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) (6)>; Stover, Kathy(NIH/NIAID) [E]- ------- (b)(6J>; Routh, Jennifer (NIH/N IAID) [E]- -------- (b) ( ·> Subject: Fwd: Seeking comment on Indian paper about new CoronavirusFYI re the paper from the Indian researchers .Talk about trying to put the genie back in the bot tle! Yeesh.From: "Mascola, John (NIH/VRC) [E]" (b)(6)Date : Sunday, February 2, 2020 at 10:39:42 AM ------- ~= To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]"(b)(6) "Hiatt, N is.s ..a- :-(:N -".I'H::-'.:/--:V:--R::~C'): ":["C -:~:]":":==::::::...;___ _,_(b, );.,~6=)> ---------- Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]"-------- (b)( >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru sAlso note the following from the author on the BioRxiv comment section:Prashant Pradhan 8 hours agoThis is a preliminary study . Considering the grave situation, it was shared in BioRxiv as soon aspossible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not ourintention to feed into the conspiracy theories and no such claims are made here. While we appreciatethe criticisms and comments provide d by scient ific colleagues at BioRxiv forum and elsewhe re, thestory has been differently interprete d and shared by social media and news platforms . We havepositively received all criticisms and comments . To avoid further misinterpretation and confusionsworld-over, we have decided to withdraw the current version of the preprint and will get back with arevised version after reanalysis, addressing the comments and concerns . Thank you to all whocontributed in this open-review process .: Authors of the ManuscriptNIH-002308From: Routh, Jennifer (NIH/NIAID) [El (b)(6) _____._. ___Sent : Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El -_-_-_-_--_- -~= C_Hb_6); Hiatt, Nissa (NIH/VRC) (CJ(b)(6)Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [ElCbH6)>B; illet, Courtney (NIH/NIAID) [El CbH6)>S; tover, Kath y(NIH/NIAID) [E) (b)(6)Subject: RE: Seeking comment on Indian paper about new CoronavirusHi Barney -We consulted with HHS and ASF. OCGR is going to send a note to the reporter to decline, noting that thepaper is not peer-reviewed. Please let us know if you receive similar requests.Thanks,JenJennifer Routh [ElNews and Science Writing BranchOffice of Communications and Government RelationsNational Institute of Allergy and Infectious Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda , MD 20892Direct: Cb)~Disclai mer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not beused by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives.From: Graham, Barney (NIH/YRC) [El ----------- (b)( Sent : Saturday, February 1, 2020 2:11 PMTo: Hiatt, Nissa (NIH/VRC) (CJ- ------- (b)( ; Routh, Jennifer (NIH/NIAID) [El (b) ( 6) >Cc: Marston , Hilary (NIH/NIAID) [El _______ C_>b_<_6>J ; Mascola, John (NIH/YRC) [El(b)(6)Subject : FW: Seeking comment on Indian paper about new CoronavirusHi Nissa and Jen,This is one we don't want to answer without high-level input, but wanted you to know about the risingcontroversy .BGNIH-002309From: lssam AHMED <lssam.AHMED@afp.com>Sent: Friday, January 31, 2020 5:27 PM -------- ~= To: Graham, Barney (NIH/YRC) [E] ________ Cb _H_6)Subject : Seeking comment on Indian paper about new CoronavirusDear Dr Graham,I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies forreaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on thispaper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf itsuggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence.Thanks you very much, if you are able.lssam Ahmedlssam AHMEDHealth, Science and Environment Correspondent1500 K St. NW - 20005 WashingtonTel : (202) 414-0521June 24 , 2020Virus death toll nears half a million as cases surge in US, Latin AmericaJoin us on:I) Cl afp.comNIH-002310From:Sent:To:Fauci, Anthony (NIH/NIAID) [E)Sun, 2 Feb 2020 17:13:03 +0000Mark DybulSubject : RE: A connection to jakeMark:Thanks for the note. Sony that l had to cancel. This is Wbite House i11 full overdrive and I am in the middle ofit. Reminiscent of post -anthrax days. I will send an email to Jake today to introduce you. Again , sorry about thecancellation. Hope to see you soon. Regards to Jason.Best ,Tony-----Original Messa.g .".e "--------------~~From: Mark Dybul (b) (6)>Sent: Sunday, February 2, 2020 11 :37 AMTo: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: A connection to jakeHey tonyKnow you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoomin hen things calm down.We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to shareMondayRealize this is last minute but mig ht it be possible for you to connect me to jake Jiang in case we can squeeze in ameeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)?Jfyou are not comfortable with that 1 could send him a cold caU email mentioning we have shared the data withyou. You were kind enough to introduce us at the nam dinner when (b) (6).Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you asusual.Thanks muchMarkSent from my iPhoneNIH-0023 13From:Sent :To:Cc:Subject:Francis:Fauci, Anthony (NIH/NIAID) [E)Sun, 2 Feb 2020 16:49:35 +0000Collins, Francis (NIH/OD) [E]Tabak, Lawrence (NIH/OD) [E]FW: TeleconferenceDo you have a minute for a quick call?TonyFrom: Jeremy Farrar (b)(6)Sent : Sunday, February 2, 2020 11:28 AMTo: Fauci, Anthony (NIH/NIAID) [E] -------= (b=)(= ; Collins, Francis (NIH/OD) [E](b)( .Cc: Tabak, Lawrence (NIH/OD) [E) --------- (b) (6)>Subject: Re: TeleconferenceTedros and Bernhard have apparently gone into conclave .... they need to decide today in my view. Ifthey do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we mighttake forward .Meanwhile ....https ://www .zerohedge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over art ificia lly-created-b iowea ponFrom: "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>Date : Sunday, 2 February 2020 at 15:30To: Jeremy Farrar CbH6J>, Francis Collins (b) (6)>Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6)Subject: RE: TeleconferenceJeremy:Sorry that I took so long to weigh in on your e-mails with Francis and me. I was onconference calls.Best regards,TonyFrom: Jeremy Farrar (b)(6)>Sent : Sunday, February 2, 2020 7:13 AMNIH-0023 14(b)(5)Cb) (5lTo: Collins, Francis (NIH/OD) [E] (b)(6)>Cc: Fauci, Anthony (NIH/NIAID) ['.:E:-] :.=====~ (b')"( "=', >; Tabak, Lawrence (NIH/OD) [E](b)(6)Subject: Re: Teleconference....R eally apprec iate us thinking through the options ... ---------------- (b)(5From: Francis Collins (b)(6)>Date: Sunday, 2 February 2020 at 12:03To: Jeremy Farrar CbH6)>Cc: "Fauci, Anthony (NIH/N IAID) [E]" --------- (b)(6), "Tabak, Lawrence (NIH/OD) [E]" (b)(6)Subject: RE: TeleconferenceHi Jeremy,Thanks for forwarding these additional reflections from Mike and Bob.FrancisFrom: Jeremy Farrar (b)(6)Sent: Sunday, February 2, 2020 6:53 AMTo: Collins, Francis (NIH/OD) [E] ------- (b..~ . c=6JCc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Tabak, Lawrence (NIH/OD) [E](b)(6)Subject: Re: TeleconferenceThank youSee thoughts overnight from others.NIH-002315(b)(5)~(b) (5)(b) (5)Jeremy(b)(5)NIH-002316From: Francis Collins CbH6)>Date: Sunday, 2 February 2020 at 10:27To: Jeremy Farrar (b)(6) "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IAID) [E]" --------- CbH6), "Tabak, Lawrence (NIH/OD) [E]" (b)(6)Subject : RE: TeleconferenceJeremy,(b) (5)I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let meknow if I can help get through his thicket of protectors.FrancisFrom: Jeremy Farrar (b)(6)Se nt: Sunday, February 2, 2020 4:48 AMTo: Andrew Rambaut (b)( >Cc: R.A.M. Fouchier (b)(6); Fauci, Anthony (NIH/NIAID) [E)(b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~= (b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes(b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=- Paul Schreier (b)(6); Ferguson, Mike(b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:....,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6)Subject: Re: TeleconferenceThis is a very complex issue.lwill:(b) (5)NIH-002317(b)(5)I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed.JeremyFrom: ' Cb(>6)Date: Sunday, 2 February 2020 at 09 :38To: Jeremy Farrar CbH6)J>Cc: f CbH6[>), "Fauci, Anthony (NIH/ NIAID) [E]"CbH~, Patrick Vallance ( CbH6)>",D rosten,Christian" I- --=========~----_;_ CbH~,M arion Koopm_a_n s ..!::::=="='=_:,0_:_:-- C_b H6)J,Edward Holmes r CbH6)jCbH~ , "Kristian G. Andersen" I (b)(6) J, Paul SchreierCbH~ Michael FMedSci ==========::=:~-------:::=======-==:,:,,:;--- (b )( ~ >, Francis Coll ins( Cb)(~CbH~ Josie Gold ing ~=========,,..,_...--------- (b )( 6)jSubject: Re: TeleconferenceDear Jeremey, Ron and all,Thanks for invitin g_m_one the call vesterda . (b)(5) ~(b)( 5)NIH-0023 18Best,AndrewOn 2 Feb 2020, at 08:40, Jeremy Farrar_ _______ C_>b<..6. ) wrote :Thanks RonThoughts on tbat very welcome.On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote:Dear Jeremy and others,This was a very useful teleconference.Thanks for organizing this on such short notice,Kind regardsNIH-0023 19(b)(5)(b) (5)(b) (5)(b) (5)RonRon's noUtfe~s_?:; ,_____________________ 71(bi ,J~i5HJNIH-002320(b)( 5)NIH-002321Van: Jeremy Farrar (b)(Datum : zaterdag 1 februari 2020 om 21:59Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------- C-bH.-.=-6)>, PatrickVallance (b)(6)CC: Christian Drosten (b)(6) "M . Koopmans" -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- (b )( 6), "R.A.M. Fouchier" =========~~--- (b )( , Edward Holmes ========:------ (b)(6)CbH6), Andrew Rambau (b)(6)"Kristian G. Andersen" (b)(6), Paul Schreier(b)((b)(6), "Ferguson, Mike"(b)(5)(b)(6) Francis Collins (b)(6),(b)(6)>, Josie Golding...========= (b:)::(:6:~)--------0nd erwerp: Re: TeleconferenceThank you to everyone for joining.There is clearly much to understand understand in this. This call was veryhelpful to hear some of our current understanding and the many gaps in ourknowledge. (b) (5)NIH-002322(b)(5)I hope that is a reasonable approach, please send any thoughts orsuggestions.(b) (5)Once again, thank you for making time over a weekend and for such aninformed discussion on a complex issue.Thank you and best wishes JeremyFrom: Jeremy Farrar (b)(6)Date: Saturday, 1 February 2020 at 15:34 -------~ = To: "Fauci, Anthony (NIH/NIA ID} [E]" (b)(6)>, PatrickVallance (b)(6)Cc: "Drosten, Christ ian" (b)( >, MarionKoopmans (b)(6)II (b) (6) EdwardrH olmes _...=..=. ==================..=.. .. (b)(6) (~b)~<~6.~)-------------(b)( ~ "Kristian G. Andersen " =========-=-=~ ----------~=(b)( ~, Paul Schreier( (b)( ~(bH ~> , Michael FMedSci ===========-~~--- (b )( ~Subject: Teleconference1st February (2nd Feb for Eddie)Information and discussion is shared in total confidence and not to beshared until agreement on next steps.Dial in details attached.Please mute phones.I will be on email throughout - email Paul or I Paul if any problemsIf you cannot make it, I will phone you afterwards to update .One HourNIH-0023236am Sydney8pmCET7pm GMT2pm EST11am PST(Hope I have the times right!)Thank you for the series of calls and for agreeing to join this call.Agenda• Introduction, focus and desired outcomes - JF• Summary - KA• Comments - EH• Q&A-AII• Summary and next steps - JFKristian AndersonBob Garry- I have not been able to contact Bob. Please forward if you can.Christian DrostenTony FauciMike FergusonRon FouchierEddie HolmesMarion KoopmansStefan PohlmannAndrew RambautPaul SchreierPatrick VallanceAn drew RambautInstitute for Evo lutionary Biolog yAshworth Laboratorie s, University of Edinburgh , Edinburgh , EH9 3FL , UKconta c t - _____ ....,~_.(.,.,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._),.,.,§)The University of Edinburg h is a charitable body, registered in Scotland, with registration numberSC005336.NIH-002324From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 15:45:28 +0000To:Subject:Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E]RE: Thank you so muchMy pleasure!From: Goldner, Shannah (NBCUniversal) <shannah .goldner@nbcuni.com>Se nt: Sunday, February 2, 2020 10:33 AMTo: Conrad, Patricia (NIH/NIA ID) [E)------- -(=bc)-(-=6) Fauci, Anthony {NIH/NIA ID) [El(b)(6)Subject: Thank you so muchDr. Fauci, thank you so much for making time for our show th is morning. We are very grateful to haveyou on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks .Sincerely - and have a good day, though I know a busy one . ShannahAnd Patric ia, thank you so much for your help and patience with me, I appreciate it.ShannahFrom: Conrad, Patricia (NIH/NIAID) [El (b)(6)>Se nt: Saturday, February 01, 2020 8:42 PMTo: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcuni. com>; Fauci, Anthony (NIH/NIAID ) [El(b)(6)Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) <Cynthia.Antoniak@MSNBC.COM>Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interviewAdding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ETlive hit as per below.If there are any changes or cancellations in the morning please call his cell at -----(b)(6) , My cell is (b)(6)Thank you.Sent from my iPhoneOn Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal)<sha n na h.goldner@n bcuni .com> wrote:NIH-002328Patricia, hi. .. the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. Thenumber at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himselfand he can park at the bureau.The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am forpowder and to be seated, that would be appreciated .The producer in NY who will email you the information details for the segment tomorrowis Cyndi Antoniak . If you need to reach her before she reaches you in the morning , heremail is Cynthia.antoniak@nbcuni.com and her phone number is (b)(6)The interview is one on one with our anchors Kendis Gibson and Cori Coffin .If you need more information, please let me know . Thank you for your help and yourpat ience today, I appreciate it.All the best,ShannahShannah GoldnerMSNBCW: 212-664-1289C: (b) (6)From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Sent: Saturday, February 01, 2020 7:54 PMTo: Goldner , Shannah (NBCUniversal) <shannah.goldner@nbcun i.com>Subject : [EXTERNAL] RE: Thank you so muchHi - are we firm for tomorrow? need onsite contact info .. thxFrom: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcun i.com>Se nt: Saturday, February 1, 2020 1:28 PM --------..-;:= To: Conrad, Patricia (NIH/NIAID) [ElCc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~H~ Stover, Kathy {NIH/NIAID)[El CbH6)>Subject: RE: Thank you so muchI will forward all that soon. Thank you!From: Conrad, Patricia (NIH/NIAID) [E] CbH ,>Sent: Saturday, February 01, 2020 1:26 PMTo: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcun i.com>Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID)[E] (b) (6)Subject : [EXTERNAL] RE: Thank you so muchNIH-002329Yes - he can do that hit time - just let us know when it is firm. He willdrive his car to the studio .I will need an onsite name and cell number for him at the studio hereindeFrom: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcun i.com>Sent: Saturday, February 1, 2020 1:20 PMTo: Conrad, Patricia (NIH/N IAID) (E]-------- (..b.)" "('=6)Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy {NIH/NIA ID)[E] (b) (6)Subject: Thank you so muchImport ance: HighPatricia, hi, thank you so much for getting back to me and again, apologies to Dr. Fauci, I dounderstand how swamped he.With that said, I'll confirm the exact time at around 2pm our time, but I think the interviewwill be at approx 7:30am.Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci tobe at the studio by 7:10am-ish?Thank you so much. ShannahFrom: Conrad, Patricia (NIH/N IAID) [E]- -------- (b)(6) Sent: Saturday, February 01, 2020 12:41 PMTo: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcun i.com>Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID)[E) (b)(6)Subject : [EXTERNAL] FW: request for a live interview tomorrow morning, on MSNBCImportance : HighGood afternoon -I believe we can make this work - if we can - it would need to be donein your NBC Studio in WDC at 4001 Nebraska Ave NWWill that work and what would the exact hit time be?NIH-002330From: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcuni. com>Sent: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6)Subject: request for a live interview tomorrow morning, on MSNBCImport ance: HighDr. Fauci, good morning.Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, todiscuss the latest news about the Coronavirus? The interview would be one on one andapprox 5mins. I saw you on the Today show yesterday and I would love to get you onMSNBC to discuss this, I know our viewers will have a better understanding of the situationif you can take us through itI can arrange a satellite location/transportation/whatever is needed to make this work out.Thank you for your consideration and I hope to hear from you soon.All the best,ShannahShannah GoldnerMSNBCW: 212-664-1289C: ----(b)-(6)NIH-002331From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 15:44:24 +0000To: Daley, George Q.Cc: Collins, Francis {NIH/OD) [El ------ (b)(6));Marston, Hilary {NIH/NIAID) [El;Graham, Barney (NIH/VRC) [ElSubject: RE: Inquiry and possible pone callGeorge:Thanks for the note . There is a lot of communications between scientists in China and theircolleagues in the USA, many with whom they have been collaborating prior to the outbreak.There is no real "coordination" of this response since we do not know who is doing what untilwe are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO isorganizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. Iam sure tha t Chinese scientists will be there. It might be helpful to contact her. Her e-mailaddress is (b)( .I hope that this is helpful. I wi ll follow-up with a call.Best,TonyFrom: Daley, George Q. (b) (6)> ------------- Se nt: Sunday, February 2, 2020 10:32 AM -----~~ To: Fauci, Anthony {NIH/NIAID) [El --------- (b)( ; Fauci, Anthony {NIH/N IAID) (El (b) ( >Subject: Inquiry and possible pone callDear Tony ,Alan Garber , Harvard 's Provost , and I met yesterday with a teamled by Jack Xia, the CEO of China's Evergrande Company , andDr Jack Liu, Evergrande 's chief health officer, who stated thywere acting on behalf of Dr Zhong Nanshan , China's ke pointperson on the coronavirus outbreak see below . CbH4>--------------------------- , andthey arranged a conference call for tomorrow morning EST withDr. Zhong.While I have been mobilizing efforts of our community to react tothe virus and to this request, I am not na"i"ve to the challengingpolitics of such a relat ionship. I do not want to complicate orduplicate efforts already underway, and am writing to requestNIH-002332whatever information you are willing to share on your currentefforts to coordinate a response.If a phone call is more facile, please do not hesitate to try my cell:------ (b)(a6n) ytime today.Sincerely,GeorgeGeorge Q. Daley, MD, PhDDean, Harvard Medical SchoolCaroline Shields Walker Professor of MedicineProfessor of Biological Chemistry and Molecular PharmacologyOffice of the Dean, Gordon Hall25 Shattuck Street, Boston MA 02115Contact: Cb(>6 )(b)(6)From: Jack Liu Cb() 6)Date: Saturday, February 1, 2020 at 11:26 PMTo: Public HMS Email CbH6)Cc: i~fflf!'f (b)(6M)~, ~ Min Chen(b)(6)Subject: Follow up on today's meetingDear Dr. Daley:Per our discussion this afternoon in the conference room at your school, --------NIH-002333(b) (4)Jack Liu, MDNIH-002334From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sun, 2 Feb 2020 15:33:34 +0000To: Collins, Francis (NIH/OD) [ElCc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia(NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [ElSubject: RE: 2019 novel Coronavirus Global research and innovation forum: towards aresearch roadmap Feb 11-12, 2020 Geneva WHO HQFrancis:This is a meeting aimed at setting research priorities and I do not believe that it impacts oroverlaps with the Tedro s proposal. I will have my staff submit some names (mostly high levelprogram people) to represent us at this meeting.TonyFrom: Collins, Francis (NIH/OD) [E] -------- (b)(6) Sent: Sunday, February 2, 2020 10:11 AMTo: Fauci, Anthony (NIH/NIAID) [El------ (=b)c(-=c>Cc: Tabak, Lawrence (NIH/OD) [E] --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) (b )( 6)Subject : FW: 2019 novel Coronavirus Global research and innovation forum : towards a researchroadmap Feb 11-12, 2020 Geneva WHO HQHi Tony ,Just encounte red this message from Soumya of WHO, inviting attendance at a meeting inGeneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal.Who would be the right persons from NIH to propose for Soumya's meeting?FrancisFrom: SWAMINATHAN, Soumya ________ CbC)_ >Sent: Friday, January 31, 2020 4:41 AM------- (b)(6) Collins, Francis {NIH/OD) [E] (b)(6) Cc: SATHIYAMOORTHYV, aseeharan (b)(6)>; RIVEROSB ALTA,A lina Ximena(b)(6)(b)(6); BORGESA, ndrea (b)(6); MCLELLAN, Faith (b)(6)>; HILL,Suzanne Rose (b)(6); GARAPO, Charity Helen (b)(6)>NIH-002335Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmapFeb 11-12, 2020 Geneva WHO HQDear All,I am delighted to inform you that WHO is organizing a global research partners forum on February 11thand 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expectedoutcome is a research roadmap with clearly defined priorit ies and a governance framework to take eachthematic area forward . Several thematic areas will be considered at the meeting, namely: virus,diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science;animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting willbe critical in consensus building on the most important research questions, as well as in building globalpartnerships and collaborations to take this work forward.This meeting is being organized in partnership with GLOPID Rand is being supported by the Bill andMelinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat withinWHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself.As the head of an agency that would play an impor tant role in addressing this new viral outbreak, eitherby undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. Iapologize for the short notice, but you will understand that we have had to plan this in the past fewdays, keeping in mind the evolving situation.Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us.Please copy (bH and (b)(6) in your response.With best wishes,SoumyaChief ScientistNIH-002336From:Sent:To:Fauci, Anthony (NIH/NIAID) [ElSun, 2 Feb 2020 12:35:48 +0000Lorsch, Jon (NIH/NIGMS) [ElSubject : RE: Update from MingExhausted, but OK. Thanks.-----Original Message-----From : Lorsch, Jon (NIH/NIGMS) [E]Sent: Sunday, February 2, 2020 7:35 AM(b)(6)To: Fauci, Anthony (NIH/NIAID) [E] .-..-_- -_-_-_~_ = C>b<.. ..Subject: Re: Update from MingJ hope you are hanging in there!JonOn 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ CbH_6)> wrote:Jon:Best,Tony-----Original Message-----From: Lorsch, Jon (NlH/NIGMS) [E] (b)( ...._.,. _____Sent: Friday, January 31, 2020 6:57 AMTo: Fauci, Anthony (NIH/NlAID) [E].__ ____ Cb _H_6lSubject: FW: Update from MingTony,JonOn 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- CbH > wrote:(b)(6)(b)(6)(b)(6)Thanks~J~o=n. .-_-----------------------------~~ (b)(6)MingSent from my iPadNIH-002337> On Jan 31, 2020, at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > wrote: >> Thanks, Ming. (b)(6) - --------------->> On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS) [E]" ______ C_b)_(6_)> wrote:>> Jon ,>> Here is an uodate of mv situation:>> Best.> Ming>NIH-002338(b)(6)From:Sent :To:(NIH/OD) [ElSubject:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 11:26:13 +0000Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, CarrieRE: More on evolution of coronavirusThe Indian paper is really out landish. Agree about Jon Cohen's nice summary.From: Collins, Francis (NIH/OD) [E] (b)(6)Se nt: Sunday, February 2, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6); Tabak, Lawrence (NIH/OD) [El---------(b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirusIn case you haven't seen, attached is the Indian paper claiming HIV sequences have been inserted into2019-nCoV, which has been roundly debunked.I found Jon Cohen's piece in Science to be a pretty useful summary :https://www .sciencemag.org/news/2020/01/mining -coronavirus -genomes-clues-outb reak-s-originsFCNIH-002339From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 04:24:27 +0000Cassetti, Cristina (NIH/NIAID) [E]Subject:Attachment s:Please handle.From: Ryan Muldoon ------------- (b)(6) Se nt: Thursday, January 30, 2020 3:33 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject : ------------ (b)(4)Dear Tony,Kind regards,RyanPrEPB1opharrnRyan MuldoonCEOTel: (b)(6) --=======L----- ~= Email (b) (6) ------------ www .prepbiop harm.comNIH-002340(b)(4l(b) (4)From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 04:2 1:44 +0000Billet, Courtney (NIH/NIAID) [E]Subject: FW: Dear Prof. Anthony Fauci, here is a request from MIT TechnologyReview ( Chinese)NIAID inquiries, please.From: Tao Sun Cb()6 )Sent: Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]- _-_-_-- -~~ CbC>_6>)Subject : Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese)Dear Prof. Anthony Fauci,Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few newquestions to ask. Chinese readers want to know the opinions of foreign independent experts1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need notpanic. What do you think of this view? In reality, Chinese residents are al ready scared and are alreadyrushing to buy masks.2 RO is a developing number, and it is not easy to calculate. Does it make sense to talk about RO at thisstage?3 You had talked about asymptomatic patients, and how public health workers should treatasymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to helpprevent epidemics?4 To what extent will the closure of Wuhan prevent the epidemic?Looking forward to your reply .BestTao Sun- ------- CbH6)>- =f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii :Dear Prof. Anthony Fauci,I am Tao Sun, a repor ter from Beijing. I am currently writing reports for the MIT TechnologyReview (Chinese) .JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and XinhuaNews Agency reported this article . Here are some questions I would like to ask you .1 Some peop le think that it is not necessary to develop a new vaccine against SARS or coronavirus inNIH-002341Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers,and secondly, such outbreaks may not return after the extinction.What do you think of these views?2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after threemonths, so is it still necessary to develop a vaccine?3 You can talk about SARS. How much does a vaccine against SARS actually play?Looking forward to your reply .TAO SUNDEEPTECH MIT Tech nology Review(b)(6)suntao@mittrchina.com7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaag District, Beijinghtt p ://www. m it tr ch i na . comTAO SUNDEEPTECH MIT Technology Review(b)(6)suntao@mittrc hina .com7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijinght tp :// www.m itt rchina.comNIH-002342From :Sent :To:Subject :Please handle.Fauci, Anthony (NIH/NIAID) [ElSun, 2 Feb 2020 04:08:48 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: Strategy to attack 2019-nCoV coronavirusFrom: Jingyue Ju (b)(6)Sent: Friday, January 31, 2020 12:39 PM ----------------- -,;-;-= To : Fauci, Anthony (NIH/NIAID) [E] (b)(6); Redfield,·_ _:_ _ ____;~.:,------------------- Robert R. (CDC/OD) (b)(6)Cc: Mary C Boyce (bH ; Lee Goldman ---------- (b)(6)>; Shelanski, Michael L.- ---------- (b)(6) Subject : Strategy to attack 2019-nCoV coronavirusDear Drs. Fauci and Redfield,Please let me know if you would like to receive the full manuscript.Thank you very much for your consideration .Sincerely,JingyueJingyue Ju, Ph.D.Samuel Ruben-Peter G. Viele Professor of EngineeringProfessor of Chemical Engineering and PharmacologyDirector, Center for Genome Technology & Biomolecular EngineeringColumbia UniversityNorthwest Corner Building, Room lOOOMlNIH-002343(b) (4)Phone: (b)(6)(0ffice) (b)(6) (Cell) ____ _,Fax: 212-851-9330Email: (b)(6)NIH-002344From:Sent :To:Subject:Arnold:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 04:08:13 +0000Arnold MantoRE: Coronavirus issuesThanks for the note. I actually have recommended to several press people that they contactyou when they ask for non-government experts. I will continue to do that.Best,TonyFrom: Arnold Manto (b) ( >Sent : Friday, January 31, 2020 1:03 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)( > Subject : Coronavirus issuesHi, Tony:As this progresses, and as other news items quiet, I am concerned that this is not being handled like the2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t rickywhen public health interventions are the way SARS was handled and remain the focus. I am beingcontacted by the media currently, not because I was in Beijing at the end of SAR$ but because of generalepidemiology credent ials I am t rying to put things into context based on past histo ry, even though Iknow other sensational information may come to light which will further muddy the waters. And weknow who will be the main muddiersKeiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was notbound by clearances etc I am trying to figure out if I can play that role here I have not yet beencontacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to(b) (4)I am attaching a paper which I wrote post 2009 which shows how the way it was handled adverselyaffected programs in much of Europe It might be of interest to those who were not around at thattime .RegardsArnoldArnold S. Manto, M.D.Thomas Francis Collegiate ProfessorDepartment of EpidemiologySchool of Public HealthUniversity of Mich igan1415 Washington HeightsAnn Arbor, Ml 48109-2029Tel: (b)(6)Fax: (734) 764-3192(b)(6)NIH-002345From:Sent:To:Fauci, Anthony (NIH/NIAID) [E)Sun, 2 Feb 2020 04:01:50 +0000toygar civelekSubject : RE: CoronavirusMany thanks!From: toygar civelek ---------- (b) (6) > Se nt: Friday, January 31, 2020 2:09 PM ------- ~= To: Fauci, Anthony {NIH/NIAID) [E]- -------- (b)(6) Subject: CoronavirusDear Mr. Fauci,I am hoping that this email reaches you as I saw this email address on line on the NIHwebsite.As we as the public get to hear, read and see with the current coronavirus scare, here inthe US and worldwide, it is comforting to have professionals and experts like you, whoreally know what they are talking about , what is going on, what can be done, timelines,action plans, and inform the public in a reliable and comforting way, yet being verytransparent, informing the public on social media.Kudos to you sir and please keep up the excellent work.Sincerely,Mur. CivelekNIH-002349From: Fauci, Anthony (NIH/NIAID) [E)Sent : Sun, 2 Feb 2020 04:01:28 +0000To: Conrad, Patricia (NIH/NIAID) [E)Cc: Greg Folkers (b)( ·Barasch, Kimberly (NIH/NIAID) [C];GregFolkers-------- ~(b~)(=6)Subject : FW: Business Council - Invitation to speak at the February 20-21, 2020 meetingat the Ritz Carlton (22nd and M St. NW), Washington, D.C.Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BC Active Members Jan. 2020.pdfI defin itely want o do this. Please respond. Thanks.From: Marlene Colucci <mcolucci@businesscouncil.com>Sent: Friday, January 31, 2020 2:00 PM ------- ~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein<David.Rubenstein@carlyle .com>; MaryPat Decker <marypat.decker@carlyle .com>Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton(22nd and M St. NW), Washington, D.C.Dear Dr. Fauci,On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of TheCarlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in ourmeeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade."(See formal inv itation attached as well as list of CEO members).We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr.Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade.We want to give our CEOs insights into what the next 10 years will bring in terms of detect ion, diagnosisand treatment of diseases. All conversations are strictly off the record and closed press. We will coverall lodging and transportation.As you know, The Business Council is comprised of the chief executive officers of the largest globalcorporations, representing all segments of the economy. We expect at least 150 CEO members, spousesand speakers to be in attendance.As a participant you and your spouse are also invited to join us for our special reception, dinner andspeaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunityfor you to meet our CEO members and spouses, speakers and other special guests in an informalatmosphere.If you are interested and available, please let me know. We can also set up a very brief call with you todiscuss any additional details and answer any questions you may have. We look forward to hearingfrom you and would be honored to have you participate with us again.Warmest regards,NIH-002350MarleneMarlene ColucciEXECUTIVEDIRECTOR'I BUSINESS~ COL NCILT: 202-298 -7650C: (b)(6)F: 202-785-0296NIH-002351From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 03:48:52 +0000Morens, David (NIH/NIAID) [E]Subject: RE: Potential PHS Officer DeploymentGot it.From:M orens, David (NIH/NIAID) [E] ---------- (b)(6) Sent: Friday, January 31, 2020 4:54 PMTo: Fauci, Anthony (NIH/NIAID) [E] -------= (b-)c(-c6-)=; Auchincloss, Hugh (NIH/N IAID) [ E](b) (6) >Subject: Potential PHS Officer DeploymentTony & Hugh, in follow up, the PHS has informed all PHS officers that as of 2/3they are subject to deployment for coronavirus work "without supervisoryapproval", meaning that if needed, officers can be deployed and assignedanywhere, for indefinite periods, by the Assistant Secretary of Health.We are hearing that many officers, especially physicians and nurses, may bedeployed for quarantine efforts and to assist State agencies.I haven't heard anything personally, but just want to let you know. Thesedeployment orders can come with almost no advance warning, although I don'texpect that.David M. Morens, M.D.CAPT, United States Public Health ServiceSenior Advisor to the DirectorOffice of the DirectorNational Institute of Allergy and Infectious DiseasesNational Institutes of HealthBuilding 31, Room 7 A-0331 Center Drive, MSC 2520Bethesda , MD 20892 -2520a (b)(6) (assistants : Kimberly Barasch; Whitney Robinson)[l§] 301 496 4409Q (b)(6)Disclaimer: This message is intended for the exclusive use of the recipient(s) named above. It may contain information that is PROTECTED,PRIVILEGEDa, nd/or CONFIDENTIALa,n d it should not be disseminated, distributed, or copied to persons not authorized to receive suchNIH-002354NIH-002355information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, anydissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the messageand its attachments and notify us immediately.From:Sent:To:Subject :Please handle.Fauci, Anthony (NIH/NIAID) [ElSun, 2 Feb 2020 03:28:01 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: Control 2019-nCoV WuhanFrom: (b)(6)Sent : Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] -----------~-~-- (b)(6)> Subje ct: Control 2019-nCoV WuhanTri-Prime Gene Pharmaceutical CoBeijing ChinaCheng YongQingCEO Tri-Prime Gene.regardsMy name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in1999 in shrimp farms in Ecuador there was a lethal disease among shrimp called the white spot virussyndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China itappeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family thatinfects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog icalmolecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimpfarms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. Theseglycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules inventedin (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepatopancreas. Cytokinins cause thedesquamation of epithelial cells from tubules that end up collapsing to the liver and shrimp pancreas.These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in theshrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp,now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019-nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhancoronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler inanimals that cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted evenwithout symptoms and its incubation is 2 to 14 days.We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan.1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in bananaplantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibitviruses. And we can give them more than 100 million liters to take for more than 100 million liters forhumans to more than 100 million inhabitants of the entire province of Hubei in China, so that they donot transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviraland antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs andimmune boosting immune response in immunocompromised people who have diabetes and high bloodpressure. Others may have cytokinin and immunoglobulin problems . We can finish with the 2019-nCoVWuhan in the environment and in humans so be found in the lungs whose epithelial cells are alreadycollapsing with an increase in inflammation and difficulty breathing . We can beat the coronav irusesNIH-002366thro ughout China.At teRobert VeraGraduated from the (b)(6) ----.!:=======~~---------- What asp p (b) (6) a. 1919 -----------s- -~ -;,:.;,, 4¾ e 1< J·,6(D abc.esABC SOCIEOAOn ~CHI NLos farm acos que pu edencomb atir el coronavirus chino<• Clcnt1lu :o<i dC'I lm,lll uto lk S,1lud de Lsl.id<l'il nidoi; p,·or,<ml'n reutitiz:.lranth irate,di,ei1 :uJo, contra L'Is :\r is Jl,1r a ncc1L•1.1 1· l:lIIL'~ad.1d L' l~1tamicnto-. . Un., fllll'\ ,1\ :,1cunapodrta <.'star lisla en solo lrt?, mcs<.'s, dict>nN. R. C.I.a. C,t?I A..t.ua ado 27/01/2020 10;0'1,Enviado desde mi smartphone Samsung Galaxy.NIH-002367From:Sent :To:Subject :Thanks, Jason.Best regards,TonyFauci, Anthony (NIH/NIAID) [E)Sat, 1 Feb 2020 23:56:07 +0000Jason GaleRE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of SpreadFrom: Jason Gale (BLOOMBERG/ NEWSROOM:) <j.gale@bloomberg.net>Sent : Saturday, February 1, 2020 6:20 PMTo: Fauci, Anthony (NIH/NIAID) [E)_ _____ ..(,b,")"("=6)Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of SpreadHello Dr Fauci ,Just been watching the press conference on You Tube with you and your federal colleagues.Thought you might find this in teresting, if you have time to breat he let alone read media reports!All the best and hope to see you at the end of next month .JasonCoronavirus Lurking in Feces May Reveal Hidden Risk of Spread2020-02 -01 06:55 :00.469 GMTBy Jason Gale(Bloomberg) -- While doctors have focused on respiratorysamples from pneumonia cases to identify coronavirus patients,they might have ignored a less apparent and hidden source of thespread: diarrhea .The novel coronavirus was detected in the loose stool ofthe first U.S. case -- a finding that hasn't featured among casereports from Wuhan, China, the epicenter of the outbreak.However, that doesn't surprise scientists who have studiedcoronaviruses , nor doctors familiar wit h the bug that causedSARS.Diarrhea occurred in about 10-20% of patients afflictedwith severe acute respiratory syndrome about 17 years ago andwas the source of an explosive SARS outbreak in the Amoy Gardensresidential complex in Hong Kong.SARS and Wuhan viruses bind to the same distinctly shapedprotein receptors in the body that are expressed in the lungsand intestines, making these organs the primary targets for bothviruses, said Fang Li, an associate professor of veterinary andbiomedical sciences at the University of Minnesota.The discovery of the Wuhan virus, dubbed 2019-nCoV, in thefecal material of the 35-year-old man treated at the ProvidenceNIH-002370NIH-002371Regional Medical Center Everett in Washington is "interesting,"said Scott Lindquist, the state epidemiologist for infectiousdisease at Washington's Department of Health."That adds to the knowledge about this,'1 he told reporterson a conference call Friday. "It's not only excreted in yourrespiratory secretions, it's also secreted in your stool."Read More: What You Need to Know About the SpreadingCoronavirusResearchers don't yet know how exactly 2019-nCoV spreadsfrom person to person, but suspect it's most likely from cominginto contact with virus -containing droplets that could beemitted by an infected person's cough and transferred to theirhands or surfaces and objects.Face MasksThat's led to a run on face masks. But those may be oflimited benefit in the event the virus is being transmitted viathe fecal-oral route, said John Nicholls, a clinical professorof pathology at the University of Hong Kong.Squat latrines, common in China, lacking covers and handsthat aren't washed thoroughly with soap and water after visitingthe bathroom could be a source of virus t ransmission, saidNicholls, who was part of the research team that isolated andcharacterized the SARS virus.A virus-laden aerosol plume emanating from a SARS patientwith diarrhea was implicated in possibly hundreds of cases atHong Kong's Amoy Gardens housing complex in 2003. That led thecity's researchers to understand the importance of the virus'sspread through the gastrointestinal tract, and to recognize boththe limitation of face masks and importance of cleanliness andhygiene, Nicholls said in an interview."I think in Wuhan, that would be a very likely place whereyou might get the transmission" from fecal material , he said."If it's using the same receptor as for SARS, I can't see why itshouldn't be replicating in the gut."Nicholls and colleagues at the University of Hong Kong aretesting laboratory models of human tissues and specimens tounderstand where and how the Wuhan virus replicates, he said.Emerging EvidenceDoctors have reported diarrhea infrequently in 2019-nCoVpatientsadmitted to Wuhan hospitals, though it's been moreprominent among reported cases outside the city, includingmembers of a Shenzhen family infected in Wuhan, and morerecently in the first U.S. case in Washington state . Thatpatient exper ienced a two -day bout of diarrhea from which aNIH-002372sample tested positive.The lab in Washington didn't attempt to grow the virus fromthat specimen, said Lindquist, the state epidemiologist,"because it wasn't going to add anything to his care."Many of the emerging coronaviruses are so-calledpneumoenteric viruses, meaning they can replicate both in therespiratory tract and the gastrointestinal system, said RalphBarie, professor of microbiology and immunology at the GillingsSchool of Global Public Health at the University of NorthCarolina at Chapel Hill, who has studied coronaviruses fordecades.Overwhelmed by hundreds of severely sick pneumoniapatients, doctors in Wuhan might not have focused on any gastricsigns, Barie said in a phone interview.'So Overwhelmed'"The Chinese are so overwhelmed at the moment and trying todo a combination of treating patients and dealing with the scopeof the outbreak, and then trying to get out papers that describewhat's happening," he said.Any virus in stool is more likely to be present during theacute phase of an infection, occuring before hospitalizedpatients develop a life -threatening complication known as acuterespiratory distress syndrome, Barie said."I have also spent most of my time focusing on therespiratory tract symptomology rather than the gut because ofthe relationship between these different emerging viruses andacute respiratory distress syndrome," he said.Zijian Feng, deputy director general of Chinese Center forDisease Control and Prevention, and colleagues released a reportWednesday on the first 425 Wuhan cases, and noted that earlyinfections that didn't appear to display typical signs -- suchas fever and viral pneumonia -- or had mild symptoms might havebeen missed."The initial focus of case detection was on patients withpneumonia, but we now understand that some patients can presentwith gastrointestinal symptoms," Feng and co-authors said intheir report, which was published in the New England Journal ofMedicine.Emerging evidence of virus-containing diarrhea warrantsfurther investigation, said Peter Collignon, a professor ofclinical medicine at the Australian Nationa l University MedicalSchool in Canberra, who advises the Australian government oninfection control."This is something new," Collignon said in an interview."We presume it's respiratory droplets, but with SARS there wasevidence of other routes . We have to keep an open mind."NIH-002373To contact the reporter on this story:Jason Gale in Melbourne at j.gale@bloomberg.netTo contact the editors responsible for this story:Brian Bremner at bbremner@bloomberg.net ;Shamim Adam at sadam2@bloomberg.netFrom:Sent:To:Subject:Please handle.Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 23:19:46 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: article from IIT/lndia on CoronovirusFrom: Hong Cai (b)(6)Sent: Saturday, February 1, 2020 5:33 PMTo: WRB Gmail <wrbrody@gmail.com>; Fauci, Anthony (NIH/NIAID) [E]Subject: Re: article from Ill /India on CoronovirusDear Fauci,(b) (4)-------- (b) (6) >I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 JThank you for your assistance in advance!-me~s, abiotec h"" ( -Hong Cai, Ph.DCo-Founder and CEOMesa Biotech, Inc.6190 Cornerstone Court East, Suite 220San Diego, CA 92121www.mesabiotech.com(b)(6)(b)(6)From: WRB (b)(6) ----------- Date : Saturday, February 1, 2020 at 7:27 AMNIH-002374(b) (4)To: "Anthony (NIH/NIAID) Fauci [E]" (b)(6)Cc: Hong Cai (b)(6)Subject: article from IIT/lndia on CoronovirusHi Tony,I hope you are coping with the chaos around coronavirus.No doubt you have seen, but in case not, I am sending a copy.Hopefully someone at NIH is try ing to replicate this study or to find problems with the irmethodology.With best wishes,BillWilliam R. Brody(b)(6~Johns Hopkins University-------- Salk Institute for Biological StudiesNIH-002375(b) (4)From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 22:06:26 +0000To:Subject:Jeremy Farrar;Collins, Francis (NIH/OD) [ElRE: TeleconferenceThanks, Jeremy. We really appreciate what you are doing here. Pleasure to work with you.Best,TonyFrom: Jeremy Farrar ________ Cb_H_6)>Se nt: Saturday, February 1, 2020 4:00 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)>Cc: Fauci, Anthony (NIH/NIAID) [El- ------- (b)(6) Subject: Re: TeleconferenceWe are altogether as you know! Conversations with you and Tony, and Patrick and others - alwaysgreat working with you bothFrom: Francis Collins (b)(6)>Date: Saturday, 1 February 2020 at 20:50To: Jeremy Farrar (b)(6)Cc: "Fauci, Anthony (NIH/N IAID) [E]" ---------- (b)( Subject: Re: TeleconferenceHi Jeremy,I can make myself available at any time 24/7 for the call with Tedros. Just let me know.Thanks for your leadership on this critical and sensitive issue.FrancisSent from my iPhoneOn Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ CbH_ > wrote:I have rejoined so a line is open if any help to rejo in.From: Jeremy Farrar ---------- (b)(6)>Date: Saturday, 1 February 2020 at 19:56To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ C~>b~<, Francis CollinsCbH >, Michael FMedSci CbH6), PatrickVallance (b)(6) ------------- Subject : Re: TeleconferenceNIH-002376Can I suggest we shut down the call and then redial in?Just for 5-l0m ins?From: Mar ion Koopmans ------------ (b)(6)Date: Saturday, 1 February 2020 at 19:43To: Jeremy Farrar CbH6J>Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._ ____________ Cb _H_6)>, Patrick VallanceCb)(~ "Drosten, Christian"(b)(~(b)({;j1>, Edward Holmes ! (b) (~,CbH6)>",K ristian G. Andersen" ! CbH~,P aul"S"-:c':h_r_e"i.e"-"r=1====-..;__----------====~ C"Hb="6'=):':]------======-C-~b)~(~ M ichael FMedSci f- -------------- Cb)~( Francis Collins I CbH~>Subject: Re: TeleconferenceOn 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote:Kristen and Eddie have shared this and will ta lk through it on the call. Thankyou.Hope it will help frame the discussions.From: Jeremy Farrar CbH6J>Date: Saturday, 1 February 2020 at 15:34NIH-002377(b) (5)NIH-0023781st February (2nd Feb for Eddie)Information and discussion is shared in total confidence and not to beshared until agreement on next steps.Dial in detail s attached.Please mute phones.I will be on email throughout - email Paul or I Paul if any problem sIf you cannot make it, I will phone you afterwards to update .One Hour6am Sydney8pm CET7pm GMT2pm EST11am PST{Hope I have the times right!)Thank you for the series of calls and for agreeing to join this call.Agenda• Introduction, focus and desired outcomes - JF• Summary - KA• Comments - EH• Q&A-AII• Summary and next steps - JFKristian AndersonBob Garry - I have not been able to contact Bob. Please forward if you can.Christian DrostenTony FauciMike FergusonRon FouchierEddie HolmesMarion KoopmansStefan PohlmannAndrew RambautNIH-002379Paul SchreierPatrick Vallance<Coronavirus sequence comparison[l] .pdf>From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sat, 1 Feb 2020 22:00:47 +0000To : Marston, Hilary (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E]Subject: FW: FOR YOUR REVIEW: Staff Communication on Novel CoronavirusAttachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx,Draft_ OH R_Flexibilities_Novel_ Coronavirus_2 .1.2020.docxPlease handle this. ThanksFrom: Myles, Renate (NIH/OD) [E] -------- (b) ( ·> Se nt: Saturday, February 1, 2020 4:12 PM ------ ..-.-,= To: Fauci, Anthony {NIH/NIAID) [El (b)(6b; Billet, Courtney (NIH/NIAID) [E](b)( >; Stover, Kathy (NIH/NIAID) [El (b)(6h ; Routh, Jennifer(NIH/NIAID) [E) (b)( >Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E]Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie-:--.-:-:-:-:-:7.::====,........_{NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El(b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth"(:N"-"I-H/-0:--:D:--): -:[-E: :)- :;=====:...~ C~)b ~(6)Subject : FOR YOUR REVIEW: Staff Communication on Novel CoronavirusGood afternoon, Dr. Fauci and team:Working in coordinat ion with OHR, ORS, OIR, and others, we have developed two communicationproducts to address questions/concerns that are being raised by NIH staff related to the novelcoronavirus. The two products are:1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities inresponse to coronavirusThese products are provided for your review and guidance. We also plan to share with HHS forreview/awareness. The current plan to disseminate these products on Monday. We look forward to yourinput.Best,RenateRenate Myles, MBADeputy Director for Public AffairsOffice of Communications and Public LiaisonNational Institutes of HealthTel: (b) (6)NIH-002380From:Sent :To:Subject:YesFauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 20:03:12 +0000Jeremy FarrarRE: TeleconferenceFrom: Jeremy Farrar (b)(6)Sent : Saturday, February 1, 2020 2:56 PMTo: Fauci, Anthony (NIH/NIAID) [E]-------= (b")'"c=" >; Collins, Francis (NIH/OD) [E](b)( ·; Ferguson, Mike (b)( ; Patrick Vallance(b)(6)Subject: Re: TeleconferenceCan I suggest we shut down the call and then redial in?Just for 5-lOmins?From: Marion Koopmans ------------ (b)(6)Date: Saturday, 1 February 2020 at 19:43To: Jeremy Farrar ! (b)(~Cc: "Fauci, Anthony (NIH/N IAID) [E]"f (bH ~ , Patrick Vallance ----""."-----:-:-:==:...-------~~ (b)( ~ >, "Drosten, Christian" I (b)(6) i>,(b)( ~ Edward Holmes(b) (~ >,(b)( ~ "Kristian G. Andersen" !Paul Schreier ! (b)( ~ --===========~~-----~======~~- Micha e I FMedScil- ----------- (bH ~ >, FrancisC ollins!- -------- (bH ~ > Subject: Re: TeleconferenceOn 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote :Kristen and Eddie have shared this and will talk through it on the call. Thank you.NIH-002381(b)(5)Hope it will help frame the discussions.From: Jeremy Farrar CbH6J>Date: Saturday, 1 February 2020 at 15:341st February (2nd Feb for Eddie)Information and discussionis shared in total confidencea nd not to be shared untilagreement on next steps.Dial in details attached.Please mute phones.I will be on email throughout - email Paul or I Paul if any problemsIf you cannot make it, I will phone you afterwards to update.One Hour6am Sydney8pm CET7pm GMT2pm EST11am PST(Hope I have the times right !)Thank you for the series of calls and for agreeing to join this call.Agenda• Introduction, focus and desired outcomes - JF• Summary- KA• Comments - EH• Q&A-AII• Summary and next steps - JFKristian AndersonBob Garry - I have not been able to contact Bob. Please forward if you can.Christian DrostenNIH-002382NIH-002383Tony FauciMike FergusonRon FouchierEddie HolmesMarion KoopmansStefan PohlmannAndrew RambautPaul SchreierPatrick Vallance<Coronavirus sequence comparison[l] .pdf>From:Sent :To:Subject:Please handle.From: Albert RizzoFauci, Anthony (NIH/NIAID) [ElSat, 1 Feb 2020 19:02:40 +0000Auchincloss, Hugh (NIH/NIAID) [ElFW: Offering assistance during this public health emergency(b)(6) -------- Sent: Friday, January 31, 2020 5:11 PM ------~~ To: Fauci,A nthony {·_N IH_/;N__ IA ID_:)_ .[.E:..]. !.:::::===-~:--- (b)(6)Cc: Harold Wimmer (b)(Subject: Offering assistance during this public health emergencyHello Dr. Fauci:As the coronavirus continues to be a public health emergency, the American Lung Association isclosely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Associationis working to help relay impo rtan t public health information provided by the various agencies.As Chief Medical Officer for the American Lung Association, and with the full support of ourCEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American LungAssociation support on strategies that wou ld be appropriate for our organization to participatein or communicate.I am happy to discuss any potent ial opportunities in which you feel we may be of assistance .Sincerely,Albert A. Rizzo MD FACP FCCPChief Medical OfficerAmerican Lung AssociationCell (b)(6)NIH-002384From:Sent :To:Subject :Please handle.Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:55:58 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: Consultancy request - CoronavirusFrom: Tatsch, Fernando Franciosi (b)(6)>Sent: Friday, January 31, 2020 6:39 PMTo: Fauci, Anthony (NIH/NIAID) [E] --------=- (b')""('=6)>Cc: Bacher, Hans P (b)(6)>; Vallabh, BhadrishSubject: RE: Consultancy request - CoronavirusDear Dr. Fauci,The below invitation is for a meeting identica l to an advisory board .We wonder if a short phone call could be beneficial to offer further context.With best regards, Fernando TatschFERNANDO TATSCH, MD, MBATherapeutic Area Head - HCV / RSVGlobal Med ical Affairs2SW 102 08 I 1 N Wauk egan Rd I North Chicago, IL 60064OFFICE (b) (6) I CELL (b) (6) I EMAIL-------- (=b)~(=6 )abbvie.com(b) (6) >This commu nic;,ti on may con t;iin info rmation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded recip ient,please note that any oth er dissemination , distrib ution, use or copying of this communication is strictly prohibi ted. Anyone who receives thismessage in erro r should not ify the sender immediately by telephone or by return e-mail and delete it from his or her computer.From: Tatsch, Fernando FranciosiSent : Thursday, January 30, 2020 4:53 PMTo· (b)(6)Subject: Consultancy request - CoronavirusDear Dr. Fauci,On behalf of AbbVie, I would like to explore your interes t and availabi lity for a scientific consultation.AbbVie is interested in your scientific view of the 2019-nCoV epidemic.Your assessment will be very informa t ive for us in the context of --------------- (b)(4)NIH-002385If you are interested, we will need a brief CV in ord er to elaborate a consultation contract .Once the contract is executed, we would like to invite you for a phone conference which will include fewmedical AbbVie colleagues .Looking fo rward to hearing from you .With best regards, Fernando TatschFERNANDO TATSCH, MD, MBATherapeutic Area Head - HCV / RSVGlobal Medical Affairs25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064OFFICE- t (b)(6) I CELLJ (b) (6)11E MAIL_ _______ ('b"~'"c'=abbvie.comThis commu nicati on may contain info rmation that is prop rietary, confident ial, or exempt from disclosure. If you are not the intended recipient,please note that any other dissemination, distr ibut ion, use or copying of this communication is strictly proh ibited. Anyone who receives th ismessage in error should not ify the sender immediate ly by telephone or by return e-mail and delete it from his or her compute r.NIH-002386From:Sent:To:Cc:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:50 :25 +0000Conrad, Patricia (NIH/NIAID) [ElSubject:Billet, Courtney (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [C]FW: 60 Minu tes/ CoronavirusIf we can fit this in next week depending on what is hitt ing the fan, I will do it.From: Conrad, Patricia (NIH/NIAID) [E] ---------(b)(6)>Sent: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El ".-i_-_ -_-__-_~_~ Cb<>.~. ..>Subject: Fwd: 60 Minute s / CoronavirusPis adviseSent from my iPhoneBegin forwarded message:From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Cb _H_j;j>Date : January 31, 2020 at 7 :52:16 PM EST -------..,,.,.., = To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ :(-b:)_:<-,-..>Cc: "Billet, Courtney (NIH/NIAID) [E]" -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) [E)" (b) (6)Subject: Fwd: 60 Minute s/ CoronavirusHi Patty,See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest analternative? Note, this isn't for on-camera - -it's background fo r a potential story .Sent from my iPhoneBegin forwarded message:From: "Lieberm an, Marc E." <MLP@cbsnews.com>Date : January 31, 2020 at 5:57 :24 PM ESTSubject: 60 Minutes / Coronavirus(b)(6)Hi, I am a producer at 60 Minutes researching a possible story about thecoronavirus outbreak. The effort to find a vaccine strikes me as interest ingand I wonder if we might be to chat about it. I am going to be in the DC areanext week. Would you have time for a brief meeting either Wednesdaymorning or Tuesday? Thanks in advance fo r your help .Best,NIH-002387Marc LiebermanMarc Lieberman I Producer I 60 Minutes I w: 212-975-6385 c: -----(b)(6) I mlp@cbsnews.comNIH-002388From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [ElSat, 1 Feb 2020 18:45:22 +0000Folkers, Greg (NIH/NIAID) [E]RE: ASF: Dan Chertow invitationNo prob lem with Dan doing this.From: Folkers, Greg (NIH/NIAID) [E] -------- CbH > Sent: Friday, January 31, 2020 10:05 PMTo: Billet, Courtney (NIH/NIAID) [E]-------=- (b')"("=' Fauci, Anthony (NIH/NIAID) [E](b)(6)>Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/N IAID) [E](b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6) Routh, Jennifer -~---~==:::!......:___....:...~ ~(NIH/NIAID) [E] (b)(6)Subject: RE: ASF: Dan Chertow invi tationAgree with CourtneyDan is a good speaker and would represent nih we llFrom: Billet, Courtney (NIH/NIAID) [El -------- (b)(6)> Sent: Friday, January 31, 2020 9:40 PM ------= = To: Fauci, Anthony (NIH/NIAID) [El CbH6J1>Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [ElCbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~(NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)>Subject: ASF: Dan Chertow invitationDan Chertow has been asked to speak at this event, which has some rather high profile participants andmedia attendance. He would like to do it.■ Do you agree?From: "Cohen, Justin (NIH/CC/OD) [E]" -------- (b)(6)>Date : Friday, January 31, 2020 at 4:43:08 PM ------~= To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]"CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney(NIH/NIAID) [El" (b)(6)-:":"".":"'.-:-:-::-:-:--:-::-:~==---- :;;;-;-,-,=Cc: "Burklow, John (NIH/OD) [El" -------- (b)(6) , "Wojtowicz, Emma (NIH/OD) [El"NIH-002389(b)(6), "NIAID NEWS {NIH/NIAID)" <---------- NIAIDNEWS@niaid.nih.gov> Subject: FW: coronavirus speaking opportunityObvious ly given the current environment (not to ment ion some of the names involved in the event),want to make sure I'm in lockstep with you all from square one . How would you like me to proceed withthe request below? The event is open to the public/ press.From: Chertow, Daniel (NIH/CC/CCMD) (El- ------- (b)(6)> Sent: Thursday, January 30, 2020 6:16 PM ------~= To: Cohen, Justin {NIH/CC/OD) [El- ------- (b)( >; Freimuth, Molly {NIH/CC/OC) [El (bH >Cc: Suffredini, Anthony (NIH/CC/CCMD) [El ______ Cb_H_6)>; Masur, Henry (NIH/CC/CCMD) [El(b)(6)Subject: FW: Hudson Institute speaking requestDear Justin,I am checking back in with you regarding the below invitation to speak.I would like to participate in this if possible.Please confirm that you have received my email.Thank you.Sincerely,DanFrom: "Asha M. George" <asha .geo rge@b iode fensecomm ission .org >Date: Thursday , January 30, 2020 at 6:09 PM ------~~ To: "Chertow, Daniel (NIH/CC/CCMD) [E]" CbH6J>Subject: Re: Hudson Institu te speaking requestDear Dan,Sorry, we have changed something slightly. Instead of taking questions directly from theaudience, we will obtain questions from the audience via email while the first part of theevent occurs, curate them, and then have them available for Senator Lieberman to askthem of the speakers.AshaAsha M. George, DrPHExecutive DirectorNIH-002390BIPARTISAN COMMISSION ON BIODEFENSE202.974.2416biodefensecommission.orgLinkedln I Twitter I Facebook I lnstagramI~ BIPARTISAN~ COMMISSIONON BIODEFENSEBeyondth e blueprintFrom: Asha M. George <asha.geor ge@biodefe nsecommission.org>Sent : Thursday, January 30, 2020 6:02 PMTo: Chertow, Daniel (NIH/CC/CCMD) [E]------ -(-b="H=6)Subject : Re: Hudson Institute speaking requestDear Dan,Here are some more specifics regarding the event we will holding at Hudson Institute onnovel coronavirus. The meeting will be on February 10th, from 2:00 - 3:30 pm in theStern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vaniaAvenue, NW, 4th floor, Washington, DC 20004.We also have the executive conference room reserv ed from 1 :30 pm on. Please plan toarrive around then, so that you can talk with Senator Lieberman and the other speakersbefore the event starts at 2:00 pm. Just ask the receptionist to direct you where to go.Here are the speakers:• Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense• Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, StrategicCommunications, Global Public Policy and Population Health , Merck; formerDirector, Centers for Disease Control and Prevention• Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP,EcoHealth Alliance• The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former DeputyAssistant to President Trump for National Security; former Special Assistant tothe President and Senior Director for Weapons of Mass Destruction andBiodefense• Mr. Eric Brown, Senior Fellow, Hudson InstituteNIH-002391NIH-002392• Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, EmergingPathogens Section , Critical Care Medicine Department , Clinical Center &Laboratory of lmmunoregulation , National Institute of Allergy and InfectiousDiseases , National Institutes of Health (invited)The setting will be relatively informal. Scooter Libby will first introduce SenatorLieberman . Then Senator Lieberman will make a short opening statement, and look toBilly to set the stage and talk about the zoonotic nature of the disease , associateddisease management considerations , etc., in about 5 minutes. The Senator will then askeach of the other speakers to say a few words from their perspectives . After that,Senator Lieberman will ask some questions of the group, allowing you all to answer andconverse. All of this should take about 45 minutes. Then we will allow the audience toask questions .We are planning for Senator Lieberman to moderate the discussion and take questionsfrom the audience , but if for some reason he cannot do so, then Billy Karesh will.I hope you will be able to make it, Dan. Let me know if you have any questions (and ifyou will be able to make it, of course) and I look forward to seeing you on February10th.AshaAsha M. George, DrPHExecutive DirectorBIPARTISAN COMMISSION ON BIODEFENSE202.974.2416biodefensecommission.orgLinkedln I Twitter I Facebook I lnstagramI~ BIPARTISAN~ COMMISSIONON BIODEFENSEBeyondth e blueprintFrom: Chertow, Daniel (NIH/CC/CCMD) [E] ______ C>bC_6>)Sent: Tuesday, January 28, 2020 7:18 PMTo: Asha M. George <asha.george@biodefen secommission.org>Subject : Re: Hudson Institute speaking requestDear Asha,Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in orderto participate.I will reach out to them now and get back to you.Thank you .DanFrom: "Asha M. George" <asha.george@ bio defensecomm ission .o rg>Date: Tuesday , January 28, 2020 at 7:15 PM ------~~ To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( >Subject: Re: Hudson Institute speaking requestDear Dan ,Thank you! The meeting will be held on February 1 oth . We are still trying to nail down atime with Senator Lieberman and Governor Ridge, so I will get back to you about that assoon as possible , hopefully tomorrow.The meeting will be open to the public and to the press, but Hudson Institute is a thinktank , so it's never a negative or rowdy crowd.AshaAsha M. George, DrPHExecutive DirectorBIPARTISAN COMMISSION ON BIODEFENSE202.974.2416biodefensecommission.orgNIH-002393Linkedln I Twitter I Facebook I lnstagrami~ BIPARTISANM. COMMISSIONON BIODEFENSEBeyondth e blueprintFrom: Chertow, Daniel (NIH/CC/CCMD) (E) (b)(6) _______... _Sent : Tuesday, January 28, 2020 5:53 PMTo: Asha M. George <asha.geo rge@b iode fensecommission.org>Subject : Re: Hudson Institute speaking requestDear Asha,I am available Feb 10th or 13th and would be happy to present to the group.Please clarify who will be in attendance and if the event is open or closed to press/public as this wouldrequi re add itional clearance on my end .Thank you.Sincerely,DanDaniel S. Chertow, MD, MPH, FCCM, FIDSACAPT, United States Public Health ServiceHead, Emerging Pathogens SectionCritical Care Medicine Department , NIH Clinical Center &Laboratory of lmmunoregulation, NIAIDFrom: "Asha M . Georg e " <asha .geo rge@b iode fensecomm issio n.o rg>Date: Monday , January 27, 2020 at 6:09 PMNIH-002394To: "Chertow, Daniel (NIH/CC/CCMD) [E]"Subject: Hudson Inst itute speaking requestDear Dr. Chertow,(b)( 6)I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired byformer Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is HudsonInstitute, one of the think tanks here in DC. Hudson lnstitute's chair of the board oftrustees (Sarah May Stern) has asked Hudson Institute to run a 90 minute meeting onthe novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ingtogether in short order .Considering your experience on the ground dealing with other outbreaks , HudsonInstitute invites you to speak at this event. In addition to one of Hudson lnstitute's Chinaexperts , we are also seeing whether Senator Lieberman and Governor Ridge areavailable to speak.Here are the dates they are a looking at: February 6, February 1 O, and February 13.Cou ld you let me know if you are available and if so , when on those dates?Thank you for your consideration, Dan. I look forward to hearing from you soon.AshaAsha M. George, DrPHExecutive DirectorBIPARTISAN COMMISSION ON BIODEFENSE202 .974.2416biodefensecommission .orgLinkedln I Twitter I Facebook I lnsta gramI~ BIPARTISAN~ COMMISSIONON BIODEFENSEBeyondth e blueprintNIH-002395From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:43:31 +0000Kristian G. AndersenSubject: RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's originsThanks, Kristian. Talk soon on the call.From: Kristian G. Andersen (b) (6)1> -------- Sent : Friday, January 31, 2020 10:32 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~------Cc: Jeremy Farrar (b) ( >Subject : Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's originsHi Tony,Thanks for sharing. Yes, I saw th is earlier today and both Eddie and myself are actually quoted in it . It's agreat article, but the problem is that our phylogenetic analyses aren't able to answer whether thesequences are unusual at indivi dual residues, except if they are completely of f. On a phylogenetic t reethe virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir .The unusual features of the virus make up a really small part of the genome (<0.1%) so one has to lookreally closely at all the sequences to see that some of the features (potentially) look engineered.We have a good team lined up to look very critically at this, so we should know much more at the end ofthe weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all findthe genome inconsistent wit h expectations from evolutionary theory . But we have to look at this muchmore closely and th ere are still further analyses to be done, so tho se opinions could still change.Best,KristianOn Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E)- ------- (b)(6)> wrote:Jeremy/Kristian:This just came ou t today. You may have seen it. If not, it is of interest to the cur rentdiscuss ion.Best,TonyFrom: Folkers, Greg (NIH/NIA ID) [E)_ ______ C>bC_6 )Sent: Friday, January 31, 2020 8:43 PMSubje ct : Science: Mining coronavirus genome s for clues to the outbreak 's originsNIH-002396As part of a long-running effort to see what viruses bats harbor, researchers in China collect one froma cave in Guandong.EcoHealth AllianceMining coronavirus genomes for clues to theoutbreak's originsBy Jon CohenJan. 31, 2020, 6:20 PMattaaaggtt tataccttcc caggtaacaa accaaccaac t ttcgatctc ttgtagatct ...That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viralpathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frighteningthe entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virusfrom patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. Theseviral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fitson the family tree of related viruses found in bats and other species. They have also given glimpsesinto what this newly discovered virus physically looks like. how it's changing, and how it might best opped."One of the biggest takeaway messages [from the viral sequences] is that there was a singleintroduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformaticsspecialist at the University of Washington, Seattle. The role of Hua nan Seafood Wholesale Market inWuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined withsampling the market's environment for the presence of the virus, is clarifying that it indeed had animportant early role in amplifying the outbreak. The vira l sequences, most researchers say, also knockdown the idea the pathogen came from a virology institute in Wuhan.In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book toproduce the virus. Although it's one of the many viruses whose genes are in the form of RNA,scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, tomake it easier to study. Many analyses of 2019-nCoV's sequences have already appeared onviro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. Thesharing of the sequences by Chinese researchers allowed public health labs around the wor ld todevelop their own diagnostics for the virus, which now has been found in 18 other countries.(Science's news stories on the outbreak can be found here.)NIH-002397When the first 2019-nCoV sequence became available, researchers placed it on a family tree ofknown coronaviruses-wh ich are abundant and infect many species-and found that it was mostclosely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at theWuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acuterespiratory syndrome (SARS), a disease whose initial outbreak was also in China more than 15 yearsago. But the SARS coronavirus has a similarly close relationship to bat viruses, and sequence datamake a powerful case that it jumped into people from a coronavirus in civets that differed fromhuman SARS viruses by as few as 10 nucleotides. That's one reason why many scientists suspectthere's an "intermediary" host species-or several-between bats and 2019-nCoV.According to Bedford 's analysis, the bat corona virus sequence that Shi Zheng-Li's team highlighted,dubbed RaTG13, differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org, a site he cofounded,Bedford has created coronavirus family trees (example below) that include bat, civet, SARS,and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it'seasy to see the differences and similar ities between the sequences.)~ .--..... .-...1. 1 ,.--·-_.- --~111(4::-1 ,-_u. ,Ill~ .. J~ ----------..-.-.--.-- ----r .._ . .-. . .1..-. . ..~......-. ....-.- --- c::=.~,:::::::•0 00 om '"" '"" fl lJ OJ• Ot •Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between theviruses with the presumed rates of mutation in other coronav iruses. So it likely took decades forRaTG13-like viruses to mutate into 2019-nCoV.Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, similarlyhas a link to bat viruses. But studies have built a compelling case it jumped to humans from camels.And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see.NIH-002398100 TGEVMlnkCoV100 Ferret CoVBat CoV CDPHE15Scotophilus bat CoV 512PEDVBat CoV HKU10Mlnlopterus bat CoV 1100Miniopterus bat CoV HKU8Human CoV NL63Bal NL63-related CoVHuman CoV 229ESADS-CoVRhinolophus bat CoV HKU2Human CoV OC43100 Murine hepatitis virusRat CoV HKU24Human CoV HKU1100 Human MERS-CoVCamel MERS-CoVPfplstra/lus bat CoV HKUSTytonycteris Bat CoV HKU4Hedgehog CoV100 100 SARS-CoV BJ0 1Civet SARS-CoV S23Bat SARSr-CoV WIV1Bat SARSr-CoV SHC014Bat SARSr-CoV L YRa11go Bat SARSr-CoV Rf1Bat SARSr-COV ZC4597 Bat SARSr-CoV HKU3-1Bat SARSr-CoV BM48-31BetaCoV/Wuha n/WIV0S /2019100 BataCo V/Wuha n/WIV02 /2019100 BetaCoV/Wuha n/WIV0-4/2 0198e taCoVrNuha nlWIV06 /2019100 BctaCoV/Wuha n/WIV07 /201997Bat CoV RaTG13Bat Hp BetaCoV Zhejiang 2013Rousettus bat CoV HKU9100 Bat CoV GCCDC1IBV0.1The longer a virus circulates in a human popu lations, the more time it has to develop mutations thatdifferentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to datediffer from each other by seven nucleotides at most, this suggests it jumped into humans veryrecently. But it remains a mystery which animal spread the virus to humans . "There's a very large grayarea between viruses detected in bats and the virus now isolated in humans," says Vincent Munster,a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronavirusesin bats, camels, and others species.Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but whetherit was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoVcases-27 of the fi rst 41 in one repor t, 26 of 47 in another -wer e connected to the Wuhan market,but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jumpinto people happened elsewhe re.NIH-002399According to Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafoodmarket has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoVand all were in the huge market's western portion, which is whe re wildlife were sold. "The positivetests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist atthe University of Sydney who collaborated with the first group to publicly release a 2019-nCoVsequence. "Such a high rate of positive tests would strongly imply that animals in the market played akey role in the emergence of the virus ."Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which,if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it'sreally, really difficult to try and determine what the natural host is," says Kristian Andersen, anevolutionary biologist at Scripps Research.One possible explanation for the confusion about where the virus first entered humans is if there wasa batch of recently infected animals sold at different marketplaces. Or an infected animal trader couldhave transmitted the virus to different people at different markets. Or, Bedford suggests, those earlycases could have been infected by viruses that didn't easily transmit and sputtered out. "It would behugely helpful to have just a sequence or two from the marketplace [environmental sampling] thatcould illuminate how man zoonoses occurred and when they occurred," Bedford says.A research group sent fecal and other bodi ly samples from bats they trapped in caves to the WuhanInstitute of Virology to search for coronaviruses.EcoHealth All ianceIn the absence of clear conclusions about the outbreak's origin, theories thrive, and some have beenscientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by theJournal of Medical Virology received substantial press coverage when it suggested that "snake is themost probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied!!-Conspiracy theories also abound. A CBC News report about the Canadian government deportingChinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted onsocial media to suggest that they were spies who had smuggled out coronaviruses. The WuhanInstitute of Virology, which is the premier lab in China that studies bat and human coronaviruses, hasalso come under fi re. "Experts debunk fringe theory linking China's coronavirus to weaponsresearch," read a headline on a story in The Washington Post that focused on the facility.Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a newblosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University,Piscataway, expressing concerns about accidental infections, which he noted repeatedly happenedNIH-002400with lab workers handling SARS in Beijing. Ebright, who has a long history of raising red flags aboutstudies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications weremade to a SARS-like virus circulating in Chinese bats to see whether it had the potential to causedisease in humans. Earlier this week, Ebright quest ioned the accuracy of Bedford's calculation thatthere are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhanvirology institute - and 2019-nCoV, arguing that the mutation rate may have been different as itpassed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV dataare "consistent with entry into the human population as a natural accident."Shi did not reply to emails from Science, but her longtime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, anew virus, the same story comes out: This is a spillover or the release of an agent or a bioengineeredvirus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yetit's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've justscratched the surface. Within that diversity, there will be some that can infect people and within thatgroup will be some that cause illness."A team of researchers from the Wuhan Institute of Virology and the Eco Health Alliance have trappedbats in caves all over China, like this one in Guangdong, to sample them for coronaviruses.EcoHealth All ianceDaszak and Sh i's group have for 8 years been trapping bats in caves around China to sample theirfeces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 otherspecies. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to theSARS virus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collectedin 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virusfrom Yunnan has high sequence identity with the new one that that's the origin," Daszak says, notingthat only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that oncewe've sampled and sampled and sampled across southern China and central China that we're going tofind many other viruses and some of them will be closer [to 2019-nCoV]."It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If wedon't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreakdies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what thereal origins of this are."Posted in:• Asia/ PacificNIH-002401• Health• Coro navi rusdoi:10 .11 26/science.abb1256Jon CohenJon is a staff writer for Science.• Email Jon• Twit te rDisclaimer : Any third-party material in this email bas been shared for internal use under fair useprovisions of U.S. copyright law, without further verification of its accuracy /veracity . It does notnecessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government.NIH-002402From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:39:50 +0000Billet, Courtney (NIH/NIAID) [E]Subject:china.Attachme nts:FW: Possible cure medically to the new coronav irus,corona virus,from wuhanmedicalcure.docxNIAID inquiries, pleaseFrom: andrew igla (b)(6)>Se nt: Saturday, February 1, 2020 2:22 AMTo: Fauci, Anthony (NIH/NIAID) [E]_ _____ ('"b'~..(-=6. )>Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china.read t his emai l.From: andrew igla (b)(6)Se nt: Tuesday, 28 January 2020 6:36 PMTo: secretary@hhs .gov <secretary@hhs.gov >Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china .From: andrew igla (b)(6)>Sent : Sunday, 26 January 2020 9:10 PMTo: secretary@ hhs.gov <secretary@hhs .gov>Subject : Possible cure medically to the new coronavirus,corona virus,from wuhan china .For secreta ry Azar th is emai l.From: andrew igla (b)(6)>Sent : Sunday, 26 January 2020 8:59 PMTo: secretary@ HHS.gov <secreta ry@HHS.gov>Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china.NIH-002403From: andrew igla (b)(6)Sent: Sunday, 26 January 2020 1:25This email is to be sent to the doctors treating medically patients in hospitals involvingthe new coronavirus,corona virus, from wuhan china.This email contains the possiblemedical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discoveredfrom an australian friend of the american people,andrew igla.This email is about orally tak ing zovirax and ciproxin together for one day.Orally taking ciproxin,inhibiting gyrase,orally taking zovirax,inhibit ing viral DNA polymerase,together at the same time, stops viral dna moving medically curing viruses in host cellsstoping duplica ting viral infected cells and stoping a virus invading new uninfected cells.Attached document contains possible medical cure to new corona virus from wuhan inchina to help you win over this virus.Dear professor and politican,My name is andrew igla and work as a research science person in denguevirus and anaconda sea snake virus.Attached is a business document for you.Thanks,Andrew igla. melbourne australia.NIH-002404From:Sent:To:Subject:Attachments :Please handle.Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:35:10 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: 2019-nCoVAminopeptidase N inhibitors and Coronaviruses-LANCET 2003.pdfFrom: Kontoyiannis,Dimitrios P _________ Cb _H_6)>Sent: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _______ _.Subject: FW: 2019-nCoVDear Dr Fauci, I enjoyed your recent editorial in JAMA re CoronavirusesAlthough the viral disease is not an area of my expertise, you might want to take a lookat a hypothesis we had proposed, long ago (back in the era of SARS), re the potential ofimmune-modulating Coronavirus infection natural history with blockage ofaminopeptidase N.I am not aware of any studies whether aminopeptidase is a receptor of China 2019-nCoV, though.SincerelyDPKDimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAASTexas 4000 Distinguished Endowed Professor For Cancer ResearchDeputy Head, Division of Internal MedicineThe University of Texas MD Anderson Cancer CenterECMM Diamond Excellence in Mycology Center/www .ecmm.infoAdj Professor Baylor College of MedicineAdj Professor UT School of Public HealthAdj Professor University of HoustonThe informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected fromdisclosure. This e-mail message may contain protected health information (PHI); dissemination of PHIshould comply with applicable federa l and state laws. If you are not the intended recipient, or anauthorized representative of the intended recipient, any further review, disclosure, use, disseminat ion,distribution, or copying of this message or any attachment (or the information contained therein) isstrictly prohibited. If you think that you have received this e-mail message in error, please not ify thesender by return e-mail and delete all references to it and its contents from your systems.NIH-002405From:Sent:To:Subject:Attachments :FYIFauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:34:43 +0000Tabak, Lawrence (NIH/OD) [E)FW: TeleconferenceCoro navirus sequence comparison[l].pdfFrom: Jeremy Farrar (b)(6)>Sent: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------Cc: Drosten , Christian (b)(6); Marion Koopmans(b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes(b)(6) Andrew Rambaut (b)(6) -----~--======~~:;;---:--:-- Krist ian G. Andersen (b)( ; Paul Schreier (b)( ;======-;- Cb(Hb~) (;~ Ferguson, Mike ._ _________ (b)(_6 ) ; Collins, Francis {NIH/OD) [E)Subject: Re: TeleconferenceKristen and Eddie have shared this and will ta lk through it on the call. Thank you.Hope it will help frame the discussions.From: Jeremy Farrar (b)(6)Date: Saturday, 1 February 2020 at 15:341st February (2nd Feb for Eddie)Information and discussion is shared in total confidence and not to be shared until agreement on nextsteps.Dial in details attached.Please mute phones .I will be on email throughout - email Paul or I Paul if any problemsIf you cannot make it, I will phone you afterwards to update .One Hour6am Sydney8pm CETNIH-002406NIH-0024077pm GMT2pm EST11am PST(Hope I have the times right!)Thank you for the series of calls and for agreeing to jo in this call.Agenda• Introduction , focus and desired outcomes - JF• Summary - KA• Comments - EH• Q&A-AII• Summary and next steps - JFKristian AndersonBob Garry - I have not been able to contact Bob. Please forward if you can.Christian DrostenTony FauciMike FergusonRon FouchierEddie HolmesMarion KoopmansStefan PohlmannAndrew RambautPaul SchreierPatrick VallanceFrom:Sent:To:Subject:Kay:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:23:07 +0000Kay JohnsonRE: thank you for continuing leadershipThank you for your kind note. Much appreciated.Best regards,TonyFrom: Kay Johnson- ---------- (b)(6) Sent: Saturday, February 1, 2020 9-:1-5- A-M-- -=-,-=, To: Fauci, Anthony (NIH/NIAID) [E)- ------- (b)(6) Subject : thank you for continuing leadershipDear Dr. Fauci - We met long ago when I was a young health policy staff person at theChildren's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around1984-86.When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-91 measlesepidemic and helped to write the measles whitepaper, I had other occasions to hear yourinsights.Since that time, I have frequently heard you on the PBS NewsHour and NPR, I see yourperspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and readJAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly youarticulate the science, the issues for public concern, and options for our nation 's response.While I've worked with many public health leaders and watched others in the media over thepast 35 years of my Maternal and Child Health public policy career, I believe no one is better atcommunications than you. It is in some ways a thank less job. I am writing to say that yourcontinuing leadership and dedication to our nation's health is deeply appreciated by me andmillions of others.Best regards, KayKay JohnsonPresident, Johnson Group Consult ing, Inc.voice: Cb) (6)fax: 802-482-3008Email: (b)(6) ----------NIH-002408From:Sent :To :Cc:Subject:Attachments :Please handle.Fauci, Anthony (NIH/NIAID) [ElSat, 1 Feb 2020 17:56:42 +0000Cassetti, Cristina (NIH/NIAID) [ElConrad, Patricia (NIH/NIAID) [ElFW: article from IIT /India on Coronovirus20200130.2019-nCOV sequence paper.927871vl.full.pdfFrom: WRB Gmail CbH >Sent: Saturday, February 1, 2020 10:27 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc: Hong Cai (b)(6)Subject: article from IIT /India on CoronovirusHi Tony,I hope you are coping with the chaos around coronavirus.I am (b)(6)1 but still active, currently chair of Mesa Biotech,No doubt you have seen, but in case not, I am sending a copy.(b)(4)Hopefully someone at NIH is trying to replicate this study or to find problems with the irmethodology .With best wishes,BillNIH-002409(b) (4)William R. Brody(b)(6) l ohns Hopkins UniversitySalk Institute for Biological StudiesNIH-002410From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 17:54:38 +0000To: Greg Folkers (b)(6)Cc: Conrad, Patricia (NIH/NIAID) [E]Subject: FW: POLITICO: New FDA chief plans for 'the most serious scenarios' ofcoronavirus outbreakWe should make a similar slide for upcoming talks.From: Folkers, Greg (NIH/N IAID) [E)- -------- (b)(6) Se nt: Saturday, February 1, 2020 10:44 AMSubject: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreakEXCLUSIVENew FDA chief plans for 'the most serious scenarios' ofcoronavirus outbreakCBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn.The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ APPhotoBy SARAH OWERMOHLE and SARAH KARLIN-SMITH01/31/2020 04:54 PM ESTUpdated: 01/31/2020 05:28 PM ESTNew FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to letstates safely import drugs. Then the Wuhan coronavirus broke out.The virus was declared a public health emergency by HHS just a few hours after Hahn's exclusiveinterview with POLITICO Friday. That kicks the agency into overdrive in multiple roles - helping speedvaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devicesthe United States needs that are made in China.AdvertisementHahn said there have not been any reports yet of disruption of the supply chain or shortages, but theagency is looking ahead and planning for "what could potentially be the most serious of scenarios." As ofnow FDA inspections in China are being conducted on a case-by-case basis.NIH-002411NIH-002412"We are taking on an individual -by-individual basis what's the regulatory need for anything in China ...versus what are the personnel risks associated," he said.Monitoring the the situation in China could soon get trickier as the State Department expandsmandatory evacuation from affected areas of the country.The coronavirus also broke out in an election year when President Donald Trump wants to deliver on hispromise to bring down drug prices - not traditionally the province of the FDA, a regulatory agencydesigned to focus on safety and efficacy ."If my patients couldn't get access to something because of cost - that was a real problem for me as adoctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows inthe best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer.Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced itsplan to let states import cheaper medicines from Canada - an approach that prior FDA commissionersopposed over fears it would jeopardize the safety of the drug supply. Trump has endorsed letting statessuch as Florida do this.WHO declares globalhealth emergencyThe novel coronavirus that first infectedpeople in Wuhan. China. has spread tomore than 20 other countries, withRussia and the U.K. report ing their firstcases of the viral pneumonia on Jan . 31.7,8186.0652019-nCoVi s a coronav1ruas t.y pe ofvirus similar to the comm°" cold, SARSartd MERS. Ir is spread by close contact 4,593with people who are inleaed. Onestudy suggests men might be moresusceptible to che virus than women.Cases confirmed by WHOASOFJAH.312,01G1,3205812,7989,826282 3146 6Jan. 20 21Cont, ed deaths170 213-17 -25 -"' 5-6 B-O 106- 132- - 23 24 25 26 27 28 29 30 31Sour~s WHOS. outhC hinaM orningP o-it.n ewsr f!ponsBy PattttSOn Clark. POLITICO Pro OataP(llnlPatterson Clark/POLITICO Pro DataPoint"There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing tohave to figure th is one out and balance both of those issues," Hahn said, referring to safety andaffordability.NIH-0024 13NIH-002414The FDA for years has mostly stayed out of the debate around drug prices; the agency doesn't regulatethe cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices downby approving more generics, acknowledging that "the American people are expecting us to do more."Trump has touted the FDA's record on boosting competition via generic approvals .As FDA works on finalizing the importation rule, Hahn said the agency will be open to addressingcriticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome.But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," hesaid.Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of newbrand-name products that are approved with limited data sets, similar to the way CMS decides to coversome medical devices. That approach - known as coverage with evidence development - let s CMScover a new prod uct on the condition that manufacturers keep providing data.FDA has not done that, but new medicines are increasingly being approved on smaller clinical trialswithout hard data on clinical benefits - and can come with six-figure price tags.As an academic, Hahn had co-written an editorial suggesting that payments for newly approvedradiation oncology devices could be linked t o older products unt il enough evidence builds up to showthat the new products are superior. Only then would manufacturers have more pricing leeway."It's a CMS call about coverage with evidence development, but I do think in this world where we areconcerned, and rightfully so, about the cost of medicine and health et cetera, that we should be lookingat all avenues to approach that, " he told POLITICO.Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly toapprove drugs without adequate evidence. But Hahn did not indicate he would put the brakes on."At the end of the day there is this balance between the gold standard and being efficient and gettingth ings in people's hands I'm totally confident in the agency's ability to do that."Hahn must balance all that while leading the FDA's response to t he Wuhan crisis, which has heightenedsome lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents ofcontamination with carcinogens."We have to be concerned about the supply chain to make sure that we have enough of what we need ifthere are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefingThursday for Energy and Commerce committee members with top health officials . The fact that Chinamanufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us tobe reexamining what we're doing in China versus what should be brought back to this country." shesaid.Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers havepressed for a clear FDA framework on selling cannabidiol, the popular hemp and marijuana byproductdecriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused infood, cosmetics and skincare products ."You cannot walk down the street without seeing the products " but there is a dearth of solid data onhow safe and effective CBD actually is, said Hahn.Those CBD challenges have fueled larger discussions about how to better regulate the vast dietarysupplement market, where manufacturers often push legal boundaries by making unverified claimsabout how herbal or homeopathic products can help people."It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to makesure that safe and effective products are in the hands of people."Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily representmy views nor those ofNIAID , NIH, HHS, or the U.S. government .From:Sent:To:Subject :OK. Stay tuned.-----Orig inal Message-----Fauci, Anthony (NIH/N IAID) [ElSat, 1 Feb 2020 17:51 :31 +0000Auchincloss, Hugh (NIH/NIA ID) [ElRE: Continu edFrom : Auchinclos s, Hugh (NlH/N IAJD) [E]...__ ______ (b~<..,.Sent : Saturday, Febrnary 1, 2020 11:47 -A-M-- -~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( >Subject: ContinuedThe paper you sent me says the experim ents were perfonn ed before the gain of function pause but have since beenrev iewed and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gonethrough the P3 framewo rk. She will try to detem1ine if we have any distant ties to this work abroad.Sent from my iPadNIH-0024 15From:Sent:To:Subject :Fauci, Anthony (NIH/NIAID) [ElSat, 1 Feb 2020 17:32:40 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On ATreatment For The Novel Wuhan CoronavirusPease handle.---<-Origi11alM essa,g,e;--:--;-;...-------~~ From: Amit Gupta (b) ( >S~nt: Saturcl..ay,F e bruary I , 2020 12:2-3 -PM- -----,;..,=.,- ,, To : Fauci , Anthony (NIH/NIAJD) [E] (b)(6) >Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Been Working On A Treahne nt For The NovelWuhan CoronavimsDear Dr. Fauci.Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You area great Scientist and Doctor.Coronavirus update: WHO says prepare for local corona virus outbreaks in other countries;What do you think about this treatment.Regards,AmitSHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the"Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novelnanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles ,that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus."We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. Diwan , PhD,President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the mostrap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen taland international agencies such as the US CDC, WHO, and Chinese CDC to successfu lly develop these treatments,and, if developed , to get them to the patients in the fastest possible time. At this time, the Company does not have acol labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked todevelop a treatment for this virus. We had collaborations with the CDC and USAMRIID in the past. The Companyintends to pursue a relevant collaboration for testing of our drug candidates soon."The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has beenshown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 ."We have already found some lead candida te ligands in our chemical library that can bind to the SARS-CoV spikepro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explainedDr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tentialtreatm ent for the new Wuhan virus. "While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some ofwhich are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates incell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu lviruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrumantiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus whereNIH-0024 16NIH-002417it intends to perform this testing.The Company has its own cGMP-capable drug manufactu ring facility. This highly custom izable faci lity can beemployed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company'sdrug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients .The Company's platform technology has already proven that it can result in safe drugs. The Company's first INDreadyclinical drug candidate , namely NV-HHV- 101, has successfu lly undergone a standard battery of Safety andToxicological testing , as previously disclosed by the Company in press releases and SEC fil ings.The Company is building on its previous work against coronaviruses . The Company's technology relies on copyingthe human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" thatwill bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to ananomicelle, to create a nanoviricide®. It is anticipated that when a virus comes in contact with the nanoviricidc, notonly would it land on the nanoviricide surface, binding to the copious number of ligands presented there, but itwould also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p,harnessing a well known biophysica l phenomenon."It is like a 'Venus-Fly- Trap' for the virus," explained Dr. Diwan.The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copyingthe specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor,and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spiteof mutations.Tn 2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses ingeneral. lt bad developed potential candidates for testing in animal models. The MERS-CoV threat was eclipsed bythe Ebola epide mic of 2015 . The Compa ny developed viable drug candidates against Ebola in a rapid response timeof a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. TheCompany believes that another cycle of optimization would have resulted in a candidate ready for animal testingunder the criteria estab lished by USAMRTJD then.During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity orthe BSL2 virology testing facility, all of which were commissioned after 2015 at its modern campus in Shelton, CT.The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials.This drug candidate, NV-HHV-101, is a skin cream with the treatment of shingles rash as its first indicat ion . It hasshown broad-spectrum activ ity against HSY- I ( cause of "cold sores"), HSV-2 ( cause of "gerutal ulcers"), and VZV(the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les inadults).NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidencethat our platform is capable of creating safe drugs.The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs forclinical supply.The Company's top priority remruns working on its first IND application for NV-HHV-l01. The Company intendsto solicit interest and financing from government agencies in order to accelerate its work on the coronaviruses .The market size for the treatment of shingles is estimated at approximately one billion dollars by various estimates.These estimates take into account the Shingrix® vaccine as well as existing vaccines. About 500,000 to 1 millioncases of shing les occur in the USA alone every year.The market size for our immediate target drugs in the HerpeCide™ program is variously estimated at billions to tensof billions of dollars. The Company believes that its dermal topical cream for the treatment of shing les rash will beNIH-002418its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in theHerpeCide™ program, namely, HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected tofollow the shing les candidate into IND-enabling development and then into human clinical trials . These additionalcandidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value.The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approachenables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - itis designed to "look like" the cell surface to the virus. The nanoviricide® technology enables direct attacks atmultip le points on a virus particle. It is believed that such attacks would lead to the virus particle becomingineffective at infecting cells. Antibodies in contrast attack a virus particle at only a maximum of two attachmentpoints per antibody. In addition, the nanovi ricide technology also simultaneously enables attacking the rapidintracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) withinthe core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of ourknowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, andsimultaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virusinfection.About NanoYiricidesNanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purposenanomaterials for antiviral therapy. The Company's novel nanoviricide® class of drug candidates are designed tospecifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 withits first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugsagainst a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC andherpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, andEbola virus, among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses todtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statementsthat reflect the Company's current expectation regarding future events. Actual events could differ materially andsubstantially from those projected hereiD and depend on a number of factors. Ce11ain statements in this release, andother written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaningof Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You shouldnot place undue reliance on forward-looking statements since they involve known and unknown risks, uncertaintiesand other factors whicb are, in some cases , beyond the Company's control and which could, and likely will,materially affect actual results , levels of activity, performance or achievements. The Company assumes noobligation to publicly update or revise these forward-looking statements for any reason, or to update the reasonsactual results could differ materially from those anticipated in these fo1ward-looking statements, even if newinfonnation becomes available in the future. Important factors that could cause actual results to differ materiallyfrom the company's expectations include, but are not limited to, those factors that are disclosed under the heading"Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securitiesand Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all suchfactors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricideis safe and effective; successful development of our product candidates; our ability to seek and obtain regulatoryapprovals, including with respect to the indications we are seeking; the successful cotmnercialization of our productcandidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . INDapplication refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, andControls".Contact:NanoViricides , Inc.info@nanoviricides.comFrom:Sent :To:Subj ect :At tac hment s:Here it isAnthony S. Fauci, MDDirectorFauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 13 :19:06 +0000Tabak, Lawrence (NIH/OD) [E)FW: IMPORTANTBarie, Shi et al - Natu re medicine - SARS Gain of function.pdfNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.NIH-002421From :Sent :To:Cc:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 12:43:22 +0000Marston, Hilary (NIH/NIAID) [E]Conrad, Patricia (NIH/NIAID) [E]Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards aresearch roadmap Feb 11-12, 2020 Geneva WHO HQAttachment s: Global Research Forum dv2AMHR AM.PDFWe need to talk about this later in the day .. I am on Conference calls now. I w ill call you later.Apparently Soumya is reaching out separate ly to other people in NIAID.From: SWAMINATHAN, Soumya ----------(b)(6) Se nt: Saturday, February 1, 2020 7:19 AMTo: Fauci, Anthony (NIH/NIAID) [E)_ _____ "("b"")"("=6")Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmapFeb 11-12, 2020 Geneva WHO HQDearTonyI am delighted to inform you that WHO is organizing a global research partners forum on February 11thand 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expectedoutcome is a research roadmap with clearly defined priorit ies and a governance framework to take eacht hematic area forward. Several thematic areas will be considered at the meeting, namely: virus,diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science;animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting willbe critical in consensus building on the most important research questions, as well as in building globalpartnerships and collaborations to take this work forward.This meeting is being organized in partnership with GLOPID Rand is being supported by the Bill andMelinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat withinWHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself.As the head of an agency that would play an impor tant role in addressing this new viral outbreak, eitherby undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. Iapologize for the short not ice, but you will understand that we have had to plan this in the past fewdays, keeping in mind the evolving situation .Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us.Please copy (b)(6) and (b)(6) in your response.With best wishes,SoumyaDr Soumya SwaminathanNIH-002422NIH-002423Chief ScientistPS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry aboutthe short notice!From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sat, 1 Feb 2020 12:32:57 +0000To: 00~Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards aresearch roadmap Feb 11-12, 2020 Geneva WHO HQAttachme nts: Global Research Forum dv2AMHR AM.PDFCliff:Whom should I nominate? See ye llow highlightTonyFrom: SWAMI NATHAN, Soumya <! (b)(6)Sent : Saturday, February 1, 2020 7:19 AMTo: Fauci, Anthony (NIH/NIAID) [E] <-!---- -(.b..H.,=6)>Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmapFeb 11-12, 2020 Geneva WHO HQDearTonyI am delighted to inform you that WHO is organizing a global research partners forum on February 11thand 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expectedoutcome is a research roadmap with clearly defined priorit ies and a governance framework to take eachthematic area forward. Several thematic areas will be considered at the meeting, namely : virus,diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science;animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting willbe critical in consensus building on the most important research questions, as well as in building globalpartnerships and collaborations to take this work forward .This meeting is being organized in partnership with GLOPID Rand is being supported by the Bill andMelinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat withinWHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself.As the head of an agency that would play an important role in addressing this new viral outbreak, eitherby undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . Iapologize for the short notice, but you will understand that we have had to plan this in the past fewdays, keeping in mind the evolving situation.Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us.Please copy (b)( and (b)(6lin your response.With best wishes,SoumyaDr Soumya SwaminathanNIH-002424NIH-002425Chief ScientistPS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry aboutthe short notice!From: Fauci, Anthony (NIH/NIAIO) [E)Sent:To: (b)(6)Sat, 1 Feb 2020 12:29:36 +0000Auchincloss, Hugh (NIH/NIAID) [C] ---------- Cc: (b )( 6)Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or iginsAs per my prior e-mail.From: Folkers, Greg (NIH/NIAID) [El- -------- (b)(6) Sent: Friday, January 31, 2020 8:43 PMSubject: Science: Mining coronavirus genomes for clues to the outbreak's originsAs part of a long-running effort to see what viruses bats harbor, researchers in China collect one from acave in Guandong.EcoHealth AllianceMining coronavirus genomes for clues to theoutbreak's originsBy Jon CohenJan. 31, 2020, 6:20 PMattaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ...That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viralpathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening theentire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus frompatients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database. These viralgenomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on thefamily tree of related viruses found in bats and other species. They have also given glimpses into whatthis newly discovered virus physically looks like, how it's changing, and how it might be stopped ."One of the biggest takeaway messages [from the viral sequences] is that there was a singleintroduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformaticsspecialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market inNIH-002426Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined withsampling the market's environment for the presence of the virus, is clarifying that it indeed had animportant early role in amplifying the outbreak. The viral sequences, most researchers say, also knockdown the idea the pathogen came from a virology institute in Wuhan.In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to producethe virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convertthe viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study.Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.org,preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences byChinese researchers allowed public health labs around the world to develop their own diagnostics forthe virus, which now has been found in 18 other countries. (Science's news stories on the outbreak canbe found here.)When the first 2019-nCoV sequence became available, researchers placed it on a family tree of knowncoronaviruses-which are abundant and infect many species-and found that it was most closelyrelated to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the WuhanInstitute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar toa bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome(SARS), a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful casethat it jumped into people from a coronavirus in civets that differed from human SARS viruses by as fewas 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" hostspecies-or several-between bats and 2019-nCoV.According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted,dubbed RaTG13, differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded,Bedford has created coronavirus family trees (example below) that include bat, civet, SARS,and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it'seasy to see the differences and similarities between the sequences.)~ -.--... 10 _,. --,---_, - '~< .- F======::~:s:: ;:=-: -u __,,aNIH-002427Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between theviruses with the presumed rate s of mutation in other coronaviruses. So it likely took decades forRaTG13-like viruses to mutate into 2019 -nCoV.Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly hasa link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And thephylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see.100too97,...-----TGEV,---- Mink CoV,..___ FerretC oV.----- Bat CoV COPHE15,----- Scotophifus bat CoV 512.__ __ PEDV.----- Bat CoV HKU10..---- Minlopterus bat CoV 1._ ___ Miniopterus bat CoV HKU8~-- Human CoV NL63---- Bat NL63-related CoV.__ ____ Human CoV 229E---~~ SAOS-CoVRhinolophus bat CoV HKU2Human CoV OC43,...__ _ Murine hepatitis virus---R at CoV HKU24 100,__ __ Human CoV HKU1100,,__ 100 -1 Human MERS-CoVCamel MERS-CoV,....__ Plpistrellus bat CoV HKUS,....__ _ TytonycterisB at CoV HKU4Hedgehog CoV90too SARS -CoV BJ01Civet SARS-CoV SZ3Bat SARSr -GoV WIV1Bat SARSr-CoV SHC014Bat SARSr-CoV L YRa11Bat SARSr-CoV Rf1Bat SARSr-CoV ZC45Bat SARSr-CoV HKU3-1,....__ _ Bat SARSr-CoV BM48-31BetaCoV/Wuhan/W IV0S/20191oo BetaCoV/Wuhan/WIV02 /2019BetaCoV/Wuhan/WIV04/2019BetaCoV/Wuh.in/WlV06 /2019100 BctaCoV/Wuhan/W1V07 /2019Bat CoV RaTG13.__ _____ Bat Hp BetaCoV Zhejiang 2013.___ ___ .----- Rousettusb at CoV HKU9100 Bat CoV GCCOC1------IBV0.1The longer a virus circulates in a human populat ions, the more time it has to develop mutations thatdifferentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differfrom each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But itrema ins a mystery which animal spread the virus to humans. "There's a very large gray area betweenviruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at theNIH-002428U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, andothers species.Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether itwas the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27of the first 41 in one report, 26 of 47 in anot her-were connected to the Wuhan market, but up to 45%,including the earliest handful , were not . This raises the possibility that the initial jump into peoplehappened elsewhere .According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafoodmarket has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoVand all were in the huge market's western portion, which is where wildlife were sold. "The positive testsfrom the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at theUniversity of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence."Such a high rate of positive tests would strongly imply that animals in the market played a key role inthe emergence of the virus."Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, ifany, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really,really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionarybiologist at Scripps Research.One possible explanation for the confusion about where the virus first entered humans is if there was abatch of recently infected animals sold at different marketplaces . Or an infected animal trader couldhave transmitted the virus to different people at different markets . Or, Bedford suggests, those earlycases could have been infected by viruses that didn't easily transmit and sputtered out. "It would behugely helpful to have just a sequence or two from the marketplace [environmental sampling] thatcould illuminate how many zoonoses occurred and when they occurred," Bedford says.A research group sent fecal and other bodily samples from bats they trapped in caves to the WuhanInstitute of Virology to search for coronaviruses.EcoHealth AllianceIn the absence of clear conclusions about the outbreak's origin, theories thrive, and some have beenscientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by theJournal of Medical Virology received substant ial press coverage when it suggested that "snake is themost probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it.Conspiracy theories also abound. A CBC News report about the Canadian government deporting Chinesescientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on socialmedia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute ofNIH-002429Virology, which is the premier lab in China that studies bat and human coronaviruses, has also comeunder fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read aheadline on a story in The Washington Post that focused on the facility.Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a newbiosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway,expressing concerns about accidental infections, which he noted repeatedly happened with lab workershandling SARS in Beijing. Ebright, who has a long history of raising red flags about studies withdangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to aSARS-like virus circulating in Chinese bats to see whether it had the potential to cause disease inhumans. Earlier this week, Ebright questioned t he accuracy of Bedford's calculat ion that there are atleast 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virologyinstitute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed throughdifferent hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent withentry into the human population as a natural accident."Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak ofthe EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a newvirus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus,"Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staringus right in the face. There' s this incredible diversity of viruses in wildlife and we've just scratched thesurface . Within that diversity, there will be some t hat can infect people and within that group wi ll besome that cause il lness."A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trappedbats in caves all over China, like this one in Guangdong, to sample them for coronaviruses.EcoHealth Allia nceDaszak and Shi's group have for 8 years been trapping bats in caves around China to sample their fecesand blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. Theyhave found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARS virus onthe family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from acave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan hashigh sequence identity with the new one that th at's the origin," Daszak says, noting that only a tinyfraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled andsampled and sampled across southern China and central China that we' re going to find many otherviruses and some of them will be closer [to 2019-nCoV] ."NIH-002430It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If wedon't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreakdies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what thereal origins of this are."Posted in;• Asia/Pacific• Health• Coronavirusdoi:10.1126/science .abb1256Jon CohenJon is a staff writer for Science.• Email Jon• Twitt erDisclaimer : Any third-party material in this email has been sbared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily repre sentmy views nor those of NlAID , NIH, HHS , or the U.S. government.NIH-002431From:Sent:To:Cc:Subject :Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 12:29:01 +0000Auchincloss, Hugh (NIH/NIAID) [C](b)(6)IMPORTANT(b)(6) -----------Attachments: Barie, Shi et al - Nature medicine - SARS Gain of function.pdfHugh:It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at7:45 AM with Azar. It likely will be over at 8:45 AM. Read this paper as well as the e-mail thatI will forward to you now. You will have tasks today that must be done.Thanks,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .NIH-002432From:Sent :To:Cc:Subject:Bob:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 02:48:59 +0000Kadlec, Robert (OS/ASPR/IO)(b)(6)FW: Science: Mining coronavirus genomes for clues to the outbreak's or iginsThis just came out today. Gives a balanced view.Best,TonyFrom: Folkers, Greg (NIH/NIA ID) [E) (b)(6)>Sent : Friday, January 31, 2020 8:43 PMSubject: Science: Mining coronavirus genomes for clues to the outbreak's originsAs part of a long-running effort to see what viruses bats harbor, researchers in China collect one from acave in Guandong.EcoHealth AllianceMining coronavirus genomes for clues to theoutbreak's originsBy Jon CohenJan. 31, 2020, 6:20 PMattaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ...That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viralpathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening theentire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus frompatients - 53 at last count in the Global Initiative on Sharing All Influenza Data database. These viralgenomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on thefamily tree of related viruses found in bats and other species. They have also given glimpses into whatthis newly discovered vi rus physically looks like, how it's changing, and how it might be stopped .NIH-002433NIH-002434"One of the biggest takeaway messages [from the viral sequences] is that there was a singleintroduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformaticsspecialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market inWuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined withsampling the market's environment for the presence of the virus, is clarifying that it indeed had animportant early role in amplifying the outbreak. The viral sequences, most researchers say, also knockdown the idea the pathogen came from a virology institute in Wuhan.In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to producethe virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convertthe viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study.Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org .preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences byChinese researchers allowed public health labs around the world to develop their own diagnostics forthe virus, which now has been found in 18 other countries. (Science's news stories on the outbreak canbe found here.)When the first 2019-nCoV sequence became available, researchers placed it on a family tree of knowncoronaviruses-which are abundant and infect many species-and found that it was most closelyrelated to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the WuhanInstitute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar toa bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome(SARS), a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful casethat it jumped into people from a coronavirus in civets that differed from human SARS viruses by as fewas 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" hostspecies-or several-between bats and 2019-nCoV.According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted,dubbed RaTG13, differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded,Bedford has created coronavirus family trees (example below) that include bat, civet, SARS,and 2019-nCoV sequences. (The trees are inte ractive-by dragging a computer mouse over them, it'seasy to see the differences and similarities between the sequences.)~-- A . ..,.., ··•-■ -.............. . ,..,.-,,I._I ._ ,__,, ------- r:===~~s =, •ou _.,..,---'I-=='--~"=' ------------------c= -----------1 =.•M.""l'"l _....-. l·. .~_.,·_- .. tf.C-,Xt1 om Cl ,u 014 auBedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between theviruses with the presumed rates of mutation in other coronaviruses. So it likely took decades forRaTG13-like viruses to mutate into 2019-nCoV.Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly hasa link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And thephylogene tic tree from Sh i's bioRxiv paper (below) makes the camel-MERS link easy to see.NIH-0024351009197100.~---TGE V.....--- Mink CoV,__ __ Ferret CoV.....---- Bat CoV CDPHE15.----- Sootophifus bat CoV 512L----PE DV~--- Bat CoV HKU 10Minlopterus bat CoV 1,__ ___ Miniopterus bat CoV HKU8.---- Human CoV NL63---- Bat NL63-related CoV.__ ___ Human CoV 229 E'-------,-,~ SADS-CoVRhfnolophus bat CoV HKU2Human CoV OC43--- Murine hepatitis virus 100 ---R at CoV HKU24---- Huma n CoV HKU1__ 100-1 Human MER S-CoV100Camel MERS-CoVPlplstrell us bat CoV HKUS--- Tytonycteris Bat CoV HKU4~- Hedgehog CoVto100 SARS-CoV 8J01Civet SARS-CoV SZ3Bat SARSr -CoV wrv1Bat SARSr -CoV SHC01 4Bat SARSr-CoV L YRa11Ba1 SARSr-CoV Rf1Bat SARSr-COV ZC45Bat SARSr-CoV HKU3- 1--- Bal SARSr-CoV BM48-31IQOBetaCoV/Wuhan/WlV0S /2019100 Beh1CoV/Wuhan/WIV02 /2019BetaCo V/Wuhan/W IV0-4/2019BetaCo V/Wuhan/W IV06/2019100 BeuCoV/Wuhan/W IV07/2019Bat CoV RaTG13,__ _____ Bat Hp BetaCoV Zhejiang 2013____ ,,...... _ Rousettusb at CoV HKU9100 Bat CoV GCCOC 1------ISVThe longer a virus circulates in a human populat ions, the more time it has to develop mutations thatdifferentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differfrom each other by seven nucleotides at most, this suggests it jumped into humans very recently . But itremains a mystery which animal spread the virus to humans. "There's a very large gray area betweenviruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at theU.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, andothers species.Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether itwas the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%,including the earliest handful , were not. This raises the possibility that the initial jump into peoplehappened elsewhere .NIH-002436According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafoodmarket has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoVand all were in the huge market's western portion, which is where wildlife were sold. "The positive testsfrom the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at theUniversity of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence."Such a high rate of positive tests would strongly imply that animals in the market played a key role inthe emergence of the virus."Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, ifany, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really,really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionarybiologist at Scripps Research.One possible explanation for the confusion about where the virus first entered humans is if there was abatch of recently infected animals sold at different marketplaces. Or an infected animal trader couldhave transmi tted the virus to different people at different markets. Or, Bedford suggests, those earlycases could have been infected by viruses that didn't easily transmit and sputtered out. "It would behugely helpful to have just a sequence or two from the marketplace [environmental sampling] thatcould illuminate how man zoonoses occurred and when they occurred," Bedford says.A research group sent fecal and other bodily samples from bats they trapped in caves to the WuhanInstitute of Virology to search for coronaviruses.EcoHealth AllianceIn the absence of clear conclusions about the outbreak's origin, theories thrive, and some have beenscientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by theJournal of Medical Virology received substant ial press coverage when it suggested that "snake is themost probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it.Conspiracy theories also abound. A CBC News report about the Canadian government deporting Chinesescientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on socialmedia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute ofVirology, which is the premier lab in China that studies bat and human coronaviruses, has also comeunder fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read aheadline on a story in The Washington Post that focused on the facility.Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a newbiosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway,expressing concerns about accidental infections, which he noted repeatedly happened with lab workershandling SARS in Beijing. Ebright, who has a long history of raising red flags about studies withNIH-002437dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to aSARS-like virus circulating in Chinese bats to see whether it had the potential to cause disease inhumans. Earlier this week, Ebright questioned t he accuracy of Bedford's calculat ion that there are atleast 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virologyinstitute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed throughdifferent hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent withentry into the human population as a natural accident."Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak ofthe EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a newvirus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus,"Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staringus right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched thesurface. Within that diversity, there will be some that can infect people and within that group wi ll besome that cause illness."A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trappedbats in caves all over China, like this one in Guangdong, to sample them for coronaviruses .EcoHealth AllianceDaszak and Shi's group have for 8 years been trapping bats in caves around China to sample their fecesand blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. Theyhave found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARS virus onthe family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from acave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan hashigh sequence identity with the new one that that's the origin," Daszak says, noting that only a tinyfraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled andsampled and sampled across southern China and central China that we're going to find many otherviruses and some of them will be closer [to 2019-nCoV]."It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If wedon't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreakdies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what thereal origins of this are."Posted in:• Asia/ Pacific• HealthNIH-002438• Coronav irusdoi :10.1126/science.abb1256Jon CohenJon is a staff writer for Science.• Email Jon• TwitterDisclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisionsof U.S. copyright law, without fm·ther verification of its accuracy /veracity . It does not necessarily repre sentmy views nor those ofNTATD, NTH, HHS , or the U.S. government.NIH-002439From:Sent :To:Subject :Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 02:46:21 +0000Mascola, John (NIH/VRC) [E)FW: Science: Mining coronavirus genomes for clues to the outbreak's or iginsHere is the Jon Cohen article.From: Folkers, Greg (NIH/NIAID) [E] (b)(6)Sent: Friday, January 31, 2020 8:43 PMSubject : Science: Mining coronavirus genomes for clues to the outbreak's or iginsAs part of a long-running effort to see what viruses bats harbor, researchers in China collect one from acave in Guandong.EcoHealth Allia nceMining coronavirus genomes for clues to theoutbreak's originsBy Jon CohenJan. 31, 2020, 6:20 PMattaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ...That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viralpathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelmi ng China and frightening theentire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus frompatients-53 at last count in the Global Initiative on Sharing All Influenza Data database. These viralgenomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on thefamily tree of related viruses found in bats and other species. They have also given glimpses into whatthis newly discovered vi rus physically looks like, how it's changing, and how it might be stopped ."One of the biggest takeaway messages [from the viral sequences] is that there was a singleintr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformaticsspecialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market inWuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined withsampling the market's environment for the presence of the virus, is clarifying that it indeed had anNIH-002440important early role in amplifying the outbreak. The viral sequences, most researchers say, also knockdown the idea the pathogen came from a virology institute in Wuhan.In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to producethe virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convertthe viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study.Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.org,preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences byChinese researchers allowed public health labs around the world to develop their own diagnostics forthe virus, which now has been found in 18 other countries. (Science's news stories on the outbreak canbe found here.)When the first 2019-nCoV sequence became available, researchers placed it on a family tree of knowncoronaviruses-which are abundant and infect many species-and found that it was most closelyrelated to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the WuhanInstitute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar toa bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome(SARS), a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful casethat it jumped into people from a coronavirus in civets that differed from human SARS viruses by as fewas 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" hostspecies-or several-between bats and 2019-nCoV.According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted,dubbed RaTG13, differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded,Bedford has created coronavirus family trees (example below) that include bat, civet, SARS,and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it'seasy to see the differences and similarities between the sequences.)----_,. ,_, -- ----~~~==:: ~;s;: .= ,uu __,IDBedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between theNIH-002441viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades forRaTG13-like viruses to mutate into 2019-nCoV.Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly hasa link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And thephylogene tic tree from Sh i's bioRxiv paper (below) makes the camel-MERS link easy to see.1009797100,...-----TGEV,---- Mink CoV'----ferret CoV.----- Bat CoV COPHE15,----- Scotophifusb at CoV 512.__ ___ PEDV.----- Bat CoV HKU10..---- Miniopterubsa t CoV 1Miniopterusb at CoV HKU8...---- Human CoV NL63---- Bat NL63-related CoV....__ ___ Human CoV 229E,___ _ ___,..,S,,A.. DS-CoVRhinolophus bat CoV HKU2Human CoV OC43Murine hepatitis virus100 .___ _ Rat CoV HKU24,__ __ Human CoV HKU1100,__•oo~ Human MERS-CoVCamel MERS-CoV'---- Pfplstre/lLJS bat CoV HKU5,__ _ Tytonycteris Bat CoV HKU4....__ _ Hedgehog CoV90too SARS-CoV BJ01Civet SARS-CoV SZ3Bat SARSr-CoV WIV1Bat SARSr-CoV SHC014Bat SARSr-CoV L YRa11Bat SARSr-CoV Rf1Bat SARSr-COV ZC45Bat SARSr-CoV HKU3-1.__ _ Bat SARSr-CoV BM48-31BetaCoV/Wuha nlWIVOS/2O19100 BetaCoV/Wuha nlWIVO2/2O19100 BetaCoV/Wuha n/WIV04/2 019BetaCoV/Wuha n/WIVO6f2O19100 BetaCoVIWuha n/WIV07/2019Bat CoV RaTG13.__ ___ Bat Hp BetaCoV Zhejiang 2013,_____ _ .----- Rousettusb at CoV HKU9.___ ____ ,av 100 Bat CoV GCCOC1Q.1The longer a virus circulates in a human populat ions, the more time it has to develop mutations thatdifferentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differfrom each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But itrema ins a mystery which animal spread the virus to humans. "There's a very large gray area betweenviruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at theU.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, andothers species.NIH-002442Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether itwas the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7of the first 41 in one report, 26 of 47 in another - were connected to the Wuhan market , but up to 45%,including the earliest handful , were not . This raises the possibility that the initial jump into peoplehappened elsewhere .According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafoodmarket has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoVand all were in the huge market's western portion, which is where wildlife were sold. "The positive testsfrom the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at theUniversity of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence."Such a high rate of positive tests would strongly imply that animals in the market played a key role inthe emergence of the virus."Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, ifany, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really,really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionarybiologist at Scripps Research.One possible explanation for the confusion about where the virus first entered humans is if there was abatch of recently infected animals sold at different marketplaces. Or an infected animal trader couldhave transmi tted the virus to different people at different markets. Or, Bedford suggests, those earlycases could have been infected by viruses that didn't easily transmit and sputtered out. "It would behugely helpful to have just a sequence or two from the marketplace [environmental sampling] thatcould illuminate how many zoonoses occurred and when they occurred," Bedford says.A research group sent fecal and other bodily samples from bats they trapped in caves to the WuhanInstitute of Virology to search for coronaviruses.EcoHealth AllianceIn the absence of clear conclusions about the outbreak's origin, theories thrive, and some have beenscientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by theJournal of Medical Virology received substant ial press coverage when it suggested that "snake is themost probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it.Conspiracy theor ies also abound. A CBC News report about the Canadian government deporting Chinesescientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on socialmedia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute ofVirology, which is the premier lab in China that studies bat and human coronaviruses, has also comeNIH-002443under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read aheadline on a story in The Washington Post that focused on the facility.Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a newbiosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway,expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rshandling SARS in Beijing. Ebright, who has a long history of raising red flags about studies withdangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to aSARS-like virus circulating in Chinese bats to see whether it had the potential to cause disease inhumans. Earlier this week, Ebright questioned t he accuracy of Bedford's calculat ion that there are atleast 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virologyinstitute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed throughdifferent hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent withentry into the human population as a natural accident."Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak ofthe EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a newvirus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus,"Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staringus right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched thesurface. Within that diversity, there will be some that can infect people and within that group wi ll besome that cause illness."A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trappedbats in caves all over China, like this one in Guangdong, to sample them for coronaviruses.EcoHealth AllianceDaszak and Shi's group have for 8 years been trapping bats in caves around China to sample their fecesand blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. Theyhave found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARS virus onthe family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from acave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan hashigh sequence identity with the new one that that's the origin," Daszak says, noting that only a tinyfraction of coronaviruses that infect bats have been discovered. " I expect that once we've sampled andsampled and sampled across southern China and central China that we're going to find many otherviruses and some of them will be closer [to 2019-nCoV)."It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If wedon't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreakNIH-002444dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what thereal origins of this are."Posted in:• Asia/Pacific• Health• Coronavirusdoi:10.1126/science .abb1256Jon CohenJon is a staff writer for Science.• Email Jon• TwitterDisclaimer: Any third-party material in this email has been shared for internal use under fair use prov isionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily repre sentmy views nor those of NlAlD, Nill, HHS, or the U.S. government.NIH-002445
------ CbH6J>Je; rnigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject : Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, asglobal infections rise(b) (5)Sound good?From: Fauci, Anthony (NIH/N IAID) [E] (b)( >Sent : Saturday, February 22, 2020 3:12:02 PMTo: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD)(b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)> _____ _,Subject : FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days,as global infec tion s riseNIH-001620Folks:TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301) 496-4409E-mail (b) (6)The information in this e-ma il and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Folkers, Greg (NIH/ NIAID) [E) --------- (b)(6) Sent : Saturda y, February 22, 2020 10:52 AMSubject : Wpost: New developments suggest coronavi rus incubation could be longer than 14 days, asglobal infections riseNew developments suggest coronavirusincubation could be longer than 14 days, asglobal infections riseNIH-001621(b) (5)Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium inWuhan in central China's Hubei province. (AP)ByAnna Fifield,Min Joo Kim andSimon DenyerFeb. 22, 2020 at 10:17 a.m. ESTThere are new indications that the incubation period for the virus could be longer than the currentlybelieved 14 days, with patients testing positive after much longer quarantine periods. This developmentcame as infections rose in South Korea, Japan, Iran and It aly and the head of the World HealthOrganization warned that the window for stopping the epidemic was narrowing .Here's what we know:• Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><."• South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases inSouth Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50confirmed cases, making it the largest hot spot in Europe.• China reported only 397 new cases Saturday, as the rate of increase continued to decline, but anaddit ional 109 people have died. There continues to be a great deal of skepticism about China'snumbers as t he criteria for diagnosing coronavirus keep changing.• A team of international epidemic experts had Wuhan added to their itinerary in China, followingquestions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused morethan 2,000 deaths in the country .• Scientists in China said they had isolated coronavirus strains in urine, raising the possibility that itmight be transmissible that way, as well as through fecal matter and respiratory droplets .NIH-001622NIH-001623BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longerthan the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria forcontain ing the virus amid an increasingly urgent effort to stop the epidemic from spreading in northeastAsia and across the world.South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said thecountry was seeing a sudden rise in coronav irus cases, with roughly 50 confi rmed in the past two days- an outb reak that represents the largest yet across Europe.Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine.A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, theepicente r of the coronaviru s outbreak.WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining thespread of the coronavirus, after cases were reported earlier in Iran and Lebanon."Although the window of opportun ity is narrowing to conta in the outbreak , we still have a chance tocontain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there will bea serious problem on our hands."Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat thesituation in the city and in surround ing Hubei prov ince "rema ins grim and complex," according to areport by the official Xinhua News Agency published Saturday."The nationw ide inflect ion point of the epidemic has not yet arrived," the report said after a meeting ofCommunist Party leaders.China' s National Health Commission reported Saturday that 397 new cases of coronav irus had beendiagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears tohave slowed markedly, although there has been a great deal of conf usion about the statistics th is weekas officials have repeatedly changed the crite ria for confi rming cases.Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed asinfected after 27 days in isolation, while a man in Jiangxi province tested posit ive after 14 days ofentralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a manin Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period withno symptoms.Coronavirus cases in South Korea skyrocket; cases triple in JapanIn Seoul, the Korea Centers for Disease Control and Prevention reported Saturday that 229 addit ionalcases of the coronav irus had been detected, taking the tota l to 433, more than doubling in the space ofa day. This makes it the worst -affected count ry outs ide China."Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, andwe're work ing closely with the government to f ully understand the transmission dynamics that led toth is increase," Tedros said.The majority of the new cases have been traced to existing clusters at a church in southern city of Daeguand a hospital in nearby Cheongdo County, according to the KCDC.The South Korean government has designated Daegu and surrounding North Gyeongsang province as"special care zones" where conta inment efforts and support will be concentrated.More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesusthe Temple of the Tabernacle of the Testimony .Since members of the church attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronaviruscases have been reported the re, includ ing two patients who died from the virus.NIH-001624The mass infection at the hospital is centered on its locked psychiatric ward, where a confinedenvironment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC.A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infectedwith the virus. He is the third person to die from the virus in South Korea.Trump was not told coronavirus-infected Americans would be flown home from cruise shipIn Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. Thatnumber excludes the 634 people on board the Diamond Princess who contracted the virus.One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, whocomplained of nausea whi le working. The mayor of Chiba city said the school will be closed untilWednesday, public broadcaster NHK reported.The teacher had not traveled abroad in the past two weeks and has no record of having been in contactwith a known infected person, underl ining the fact that the virus is now spreading almost invisiblythroughout the country, experts say.Quarantines in effect in parts of Italy amid sudden spike in casesAs numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, askingsome 50,000 people to stay indoors and suspending all public events - including religious ceremoniesand school - in 10 small towns to the south of Milan.Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists."There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northernLombardy region, which has seen the majority of the cases.Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday saidthat a 77-year-old woman had also tested positive for the virus after being found dead in her home. ButItalian authorities said the woman suffered from other health conditions, and were unsure if it was thevirus that had killed her.As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, whichincludes the country's financial hub, Milan . There were another 12 cases in the neighboring northernregion of Veneto.The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus isjumping from one place to the next."It goes to show you that having other cases of contagion is absolutely possible," Zaia said.According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearoldwho'd had dinner with somebody who had j ust come back from China. But some three weeks passedbetween that dinner and the time the man came down with a fever. In between, he ran a halfmarathon,played soccer and traveled to several towns, according to La Repubblica, a major Italiandaily .Iran, meanwhile, announced its fifth death from t he virus, raising the country's overall total confirmedcases to twenty eight .Efforts to clear the Diamond Princess cruise ship continueMeanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crewmembers have so far been found to have the virus.All of the passengers have now been tested and almost all have left the ship, either to go home if theytested negative, to local hospitals or government facilities if they have the virus, or back to their homecountries.Some passengers were asked to stay on board to serve an additional quarantine if their cabin matecontracted the virus, but this group is also disembarking Saturday to serve out the rest of theirquarantine in a government facility, local media reported .In China's 'war' on coronavirus. hospita ls turn away ot her pat ients - with dire resultsNIH-001625More than 200 port calls in Japan by international cruise ships have been canceled since the beginningof February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lostrevenue from passengers coming ashore dealing another blow to Japan's weak economy .Controversy continues to simmer about the infection control procedures on board the ship, after adoctor complained on Tuesday about "chaotic" and scary conditions on board .Six people working on the boat or with the passengers, including four government officials, a medic andan ambulance driver, have contracted the virus.Media reports questioned why about 90 government officials who worked on the ship have returned towork without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato saidthe government is "trying to confirm what operations staff were involved in specifically."Amer ican woman in Malays ia declared free of coronavirusThe 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpurairport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysiahealth authorities said Saturday.The woman "is showing good improvement and signs of recovery, however, she is still being monitoredand managed in hospital for a slight cough," Malaysia's director general of health, Noor HishamAbdullah, said in a st atement.The woman repeatedly tested negative while on board the ship and when she disembarked inSihanoukville, then twice tested positive while transiting in Kuala Lumpur airport on Feb. 15. That set offa global scramble to track the hundreds of other passengers who had also disembarked then boardedplanes bound for home.The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and sheshowed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted24 hours apart, both came back negative for coronavirus.But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was everinfected, saying she "never had coronavirus to our knowledge .""I have confirmed that all the passengers were tested, and they have come back negative forcoronavirus, including the person who initially tested positive ," USA Today quoted CDC spokespersonRichard Quartarone as saying. The woman " may have had a respiratory illness, but if she did, it was notcovid-19," he said, using the official name for the virus.Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on boardthe Westerdam and the 781 passengers who were still in the country of coronavirus infection .Chinese scientists isolate coronavirus strains in urine as WHO prepares visitSeparately, scientists in China are continuing to study how the virus is transmitted .A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irusstrains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State KeyLaboratory, told reporters in Guangdong on Saturday.The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets,appeared to be transmissible through fecal matter, underscoring the need to practice good handwashing as a preventive measure.Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strainshad been isolated and that this had implications for public health control. They are cont inuing to workon isolating the virus and on a cure, the Guangzhou Daily reported.But he said people should pay more attention to personal and family hygiene to prevent the spread ofthe virus and recommended frequently washing hands, closing the toilet lid before flushing and makingsure bathroom drains are not blocked.NIH-001626WHO experts have also been on an investigative mission in China this week, holding meetings in Beijingand traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel toWuhan, where the outbreak began at a live animal market and which remains under strict lockdown inan effort to contain the virus.This had led to speculation that the Chinese government, which has come under fire for its slowresponse to the outbreak and where medical workers are stretched to the limit, did not want theexperts to visit.But the WHO said late Friday that the experts would be travel ing to the center of the outbreak onSaturday, although they gave no further information about their itinerary .Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and ChicoHarlan and Stefano Pitrelli in Rome contributed reporting.Two Beijing hospit als quarantine d amid fears coronav irus infect ions will spike in t he capita lConfusion mounts over China' s count ing met hods as coronav irus numbers swing wildlyCoronavirus claims lives of two passengers from Diamond Princess cruise ship, Japanese media saysToday1s coverage from Post corr espondents around t he worldLike Washingt on Post World on Facebook and stay updat ed on fo reign newsDisclaimer : Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily representmy views nor those ofNIATD, NTH, HHS, or the U.S. government.From:Sent :Fauci, Anthony (NIH/NIAIO) [ElSat, 22 Feb 2020 18:35:29 +0000To:Subject:Mermin, Jonathan (CDC/DDID/NCHHSTP/OD)RE: COVID-19Jono:Many thanks for your kind note. Much appreciated. I hope th at all is we ll withyo u.Best regards,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone Cb) (6)FAX: (301 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) ------ CbH > Sent : Saturday, February 22, 2020 1:14 PM ------=--c= To: Fauci, Anthony (NIH/NIAID) [El CbH6)>Subject: COVIO-19Tony:I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstandingwork .Best,JonoNIH-001651From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Fri, 21 Feb 202011:59:09 +0000To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, RachelBarwick (CDC/0D1D/NCEZID/DGMQ)Subject: RE: Infectious disease advice for NSO Asia tourThanks, Marty.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6lThe information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) ------(b)( > Se nt : Friday, February 21, 2020 6:31 AM -------= = To: Fauci, Anthony (NIH/NIAID) [E] --------- (b)( ; Collins, Francis (NIH/OD) [El (b )(Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS)------ (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSO Asia tourTony and FrancisHappy to be a POC fo r Deborah . She can text me (b)(6)and we can arrange a time to speak. Mycell recept ion in EOC not great. Alternative ly EOC can track me down (b)(6)Email pretty clogged these days ...Best,MSCGet Out look for iOSFrom: Fauci, Anthony (NIH/N IAID) [El -------- CbH > Se nt: Friday, February 21, 2020 5:46:50 AMTo: Collins, Francis (NIH/OD) [E] -------- (b)(6)NIH-001694Cc:C etron, Marty (CDC/DDID/NCEZID/DGMQ)_ ___(b)( ._..>..; C onrad, Patricia (NIH/NIA ID) [E](b)(6)Subject: RE: Infectious disease advice for NSO Asia tourFrancis:(b)(5)------------- (b) (5) The best person in the wor ld for this is Marty Cetron at the CDC. am copying him on this e-mail. Perhaps he can direc tly get back to you.Best,Tony-----Original Message-----From: Collins, Francis (NIH/OD) [E] -------- (b)(6)Sent: Friday, February 21, 2020 5:21 AM -------=-:-:= To: Fauci, Anthony (NIH/NIAID) [El- -------- (b)(6) Subject: FW: Infectious disease advice for NSO Asia tourHi Tony,See below from Deborah Rutter, the head of the Kennedy Center .Who would you recommend at NIH or CDC to be a contact?Francis-----Original Message-----From: Rutter, Deborah F.<DFRutter@Kennedy-Center .org>Sent: Thursday, February 20, 2020 5:59 PMTo: Collins, Francis (NIH/OD) [El (b)( >Cc: Ginstling, Gary <GGinstling@Kennedy-Center .org>Subject: Infectious disease advice for NSO Asia tourDear Francis(b) (5) ------------As you may know, the National Symphony Orchestra has long had an Asia your on its schedule for Marchthis year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks agobut the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of themembers and our management are looking for addit ional advice on travel concerns and any infectiousdisease warning/direction. Would you have someone amongst your brilliant colleagues who could be aresource to our team?I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you somuch for any direction you can offer us!DeborahNIH-001695NIH-001696This e-mail message is intended only for the recipient(s) named above. This message may contain tradesecrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission, dissemination, reproduction or other use of, or taking of any action in reliance upon, thisinformation by persons or entities other than the intended recipient is prohibited. If you received this inerror , please contact the Sender and delete the material from any computer .From:Sent:To:(b)(6)Tue, 18 Feb 2020 15:41:35 -0500Conrad, Patricia (NIH/NIAID) [E)Subject: Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 MarchLet us discuss.Begin forwarded message:From: "Wolfe , Mitchell (CDC/OD)" ------- (b)(6) Date: February 18, 2020 at l :08:55 PM ESTTo: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~Cc: "Conrad, Patricia (NIH/NIAID) [E]"(b)(Subject: F,v: Lunch with AMB at Thai Residence on 27 Feb or 4 MarchTony,The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4March. They didn't have your contact and asked (per below) if I could contact you toask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If youor your staff can let me know, I will get back with them.Best regards,Mitchell Wolfe, MD, MPHRADM, USPHSChief Medical Officer, Office of the DirectorCenters for Disease Control and PreventionPh:- ----(b)(6)From: Panupat Chavananikul <panupatc@thaiembdc.org>Sent: Tuesday, February 18, 2020 12:42 PMTo: Wolfe, Mitchell (CDC/OD) (b)(6)Cc: Chuliepote lsarankura Na Ayudhaya <chuliepotei@thaiembdc .org>Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 MarchDear P Mitch krub,Ref: invita t ion for Lunch on 27 Feb OR 4 March1. Hope all is well with you. Hopefully you had some rest last weekend. Since you wereliving in Thailand for a while you must be missing authentic Thai food . Ambassador ThaniNIH-001780wiould like to extend his invitation to you and CDC colleagues to have lunch at Thairesidence either on Thursday 27 Feb or Wednesday 4 March at 12.30 pm. His residencelocated at (b)(6) You may invite your colleagues who involve inCoronavirus or Thailand, and please let me know their name and ranking as well as youravailable date.For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some ofour colleagues.2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC,on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci alsoreceived Prince Mahido l award back in 2013 . Ambassador would also like to have him joinour lunch at his residence as well.Is it possible that you may reach out to him to see whether he can have lunch with us ornot, OR you may provide me his contact detai ls.Thank you krub &Best wishes,Panupat (boat)Mr .Panupat ChavananikulCounsellor (Consul)Royal Thai EmbassyCell Cb) (6)Work 202 640-5308NIH-001781From:Sent :To:Fauci, Anthony (NIH/NIAI0) [E)Tue, 18 Feb 2020 14:57:27 +0000Redfield, Robert R. (CDC/OD)Subject :Attachments :RE: Severity Assessment for U.S. Response - CDCSeverity Assessment for U.S. Response - CDC.docxBob:See my minor tra cked edits.Thanks,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who Is not the original Intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From : Redfield, Robert R. (CDC/OD) (b) (6)Sent : Tuesday, February 18, 2020 9:35 AMTo: Fauci, Anthony (NIH/NIAID) [E)_ _____ _,(_b_ )- ,(-6=)Subject : Fwd: Severity Assessment for U.S. Response - CDCTake a look ?edits thoughtsOr. Robert RedfieldFrom : Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6)Sent: Monday, February 17, 2020 10:48:48 PMTo: Redfield, Robert R. (CDC/OD) (b)(6)Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ)------ CbH6J>B;u tler, Jay C. (CDC/DDID/O0) CbH6J> Subject : Severity Assessment for U.S. Response - CDCDr. Redfield:Here is the severity assessment in response to your request from yesterday. Take a look and see if thisaddresses your request.DanNIH-001784From:Sent:Fauci, Anthony (NIH/NIAID) [E)Wed, 19 Feb 2020 12:03:04 +0000To: Marks, Peter;Schuchat, Anne MD (CDC/OD)Cc: Cho, David S (CBER) (FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston,Hilary (NIH/NIAID) [E]Subject: RE: Covid-19 Survival on SurfacesPeter:Vincent Munster at NIAi D's RML has done work on thi s. I am copying him onthis e-mail.Best,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Marks, Peter Cb) ( >Sent: Wednesday, February 19, 2020 6:41 AMTo: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E](b)(6)Cc: Cho, David S (CBER)( FDA/CBER)- -------- (b)(6) Subject: Covid-19 Survival on SurfacesDear Anne and Tony,I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDC who iswork ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on variousproducts and other perishab le items. The food safety people here at FDA are quite concerned about thelatter, given published reports of differential coronavirus surv ival on various surfaces.If it turns out that this has not been evaluated, or is not in the process of being evaluated, we are happyto work on this in our BSL-3 labs, which are now in receipt of the v irus.NIH-001763NIH-001764Thanks so much for any direction that you can provide.Best Regards,PeterFrom: Fauci, Anthony (NIH/NIAID) [E)Sent : Sat, 15 Feb 2020 12:55:47 +0000To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman,Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [ElCc: Holland, Steven (NIH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen(NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [ElSubject: RE: COVID-19 messaging(b) (5)From: Gilman , James (NIH/CC/OD) [El (b)(6)Sent: Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El(b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara"(:N"":"l.~H"./-' :0-::-D:-~:) "[:E"~]: ====~__,_., (b).,.(.6=; ) >; Fauci, Anthony (NIH/N IAID) [E] CbH >Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>J; ohnson, Alfred (NIH/OD) [E](b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Cb)( ; Schmitt,James (NIH/OD/ORS) [El (b)(6)Subject: Re: COVID-19 messaging(b) (5)JimFrom: "Collins, Francis (NIH/OD) [El" CbH6J>Date : Friday, February 14, 2020 at 8:04:30 PMTo: "Gottesman , Michael (NIH/OD) [E)"--------aa- Cb~H=6J>, "Tabak, Lawrence (NIH/OD) [E]"(b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (b)( >, "Fauci, Anthony---:----:-~~==:::!....:--~~(NIH/NIAID) [El" Cb)( >Cc: "Holland, Steven (NIH/NIAID) [El" (b)( >, "Johnson, Alfred (NIH/OD) [El"---------- (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) ,11 Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El"(b)(6)>Subject: RE: COVID-19 messaging1111Lo oping in Jim Gilman .FCFrom: Gottesman, Michael (NIH/OD) [E]Sent : Friday, February 14, 2020 6:03 PM(b)(6)>NIH-001869To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El--.--.~~==:!:...,_(b_)( 6); C_o lli_ns_, _F;r~an~c is (NIH/OD) [El (b)(6)>; Fauci, Anthony(NIH/NIAID) [El (b)(6)>Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E](b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt,James (NIH/OD/ORS) [El CbH6J>Subject : COVID-19 messagingWe have had many requests for additional guidance concerning staff potentially exposed to COVID-19.OMS has prepared the attached message which has been reviewed by Steve Holland and HR.The intent is to send t his from OMS to all hands.MichaelNIH-001870From:Sent :To:Subject :Attachments :Fauci, Anthony (NIH/NIAIO) [E)Sat, 15 Feb 2020 02:23:37 +0000Holland, Steven (NIH/NIAID) [E]RE: COVID-19 messagingCOVID-smh - with Fauci edits .docxSteve:See m',' tracked edits.Thanks,TonyFrom: Holland, Steven (NIH/NIAID) [E]- -------- (b) (6)> Sent: Friday, February 14, 2020 9:06 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [E] ______ Cb><_ >Subject : FW: COVID-19 messagingTony,Could you please look at the attached and make any edits you think would help .SteveDirector , Division of Intramural ResearchNational Institute of Allergy and Infectious DiseasesNational Institutes of HealthBldg. 10/11N248 MSC 1960Bethesda, MD 20892-1960-----(b) (6)voice 301-480-4507 fax----(-b) (6) emailAssistan t lab: Eva Portillo~==~~--- (b)(6) emai l ----(-b) (6) voiceAssistant to SD: Beth SchmidtNIH-001871(b) (5)(b)(5)(b)(5) ~(b)(5)(b)(6)----(b) (6) voiceFrom: "Gottesman, Michael (NIH/OD) [E]" --------- (b)(6 )>Date: Friday, February 14, 2020 at 6:12 PM -------~~ To: "Schmitt, James (NIH/OD/ORS) [E]." .========;:(-b)=(6) -,;:-- Cc: "Moss, Bradley (NIH/OD/ORS) [E)"- -------- (b)(6) Steven Holland (b )( 6)Subject : Re: COVID-19 messaging- · This can wait until next week.MichaelFrom: "Schmitt, James (NIH/OD/ORS) [E]"- -------- (b)(6) Date: Friday, February 14, 2020 at 6:07 PM -------~= To: "Gottesman, Michae l (NIH/OD) [E]" Cb)( >Subject: FW: COVID-19 messagingI meant to copy you on this Michael. JimFrom: Schmitt, James (NIH/OD/ORS) [ElSent: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El- -------- (b)(6)>; Bailin, Heike (b)(6)Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6)(b) (5)----------- (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) [E) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E) (b)(6)>; Tosten, Timothy(NIH/OD/ORS) [E) (b)(6)Subject: FW: COVID-19 messagingHi Bra d,It sounds like Dr. Gottesman wants this sent from OMS to everyone.I don't know how to do that. Can you help us with this and how soon can it be sent?I'm heading out of town and won't retmn to the clin ic until Tuesday . Dr. Bailin will bein charge of OMS in my absence.JimJames M. Schmill, M.D., M.S.Medical DirectorOccupational Medjcal Service, DOHSNIH-001872National In stitutes of Hea lthIO Center DriveBethesda, MD 20892-1584(b)(6)From: Gottesman, Michael (NIH/OD) [E] (b)(6)>Sent : Friday, February 14, 2020 6:03 PM ------- ~= To: Tabak, Lawrence (NIH/OD) (E] (b)( >; Schwetz, Tara {NIH/OD) [E](b)(6); Collins, Francis (NIH/OD) [E) (b)(6)>; Fauci, Anthony7( N- l'H."7'/"N- I"A"l.-'D:"--): -:[-E: -): . ==:::::;.--~ ("b'~=(6)>Cc : Holland, Steven (NIH/NIA ID) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E]--------- (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] (b)( >; Schmitt , James (NIH/OD/ORS ) [E] CbH6)>Subject : COVID-19 messagingWe have had many reques ts for additional guidance concerning staff potentially exposed toCOVID-19. OMS has prepared the attached message which has been reviewed by Steve Hollandand HR.The intent is to send this from OMS to all hands.MichaelNIH-001873From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sat, 15 Feb 2020 02:08:57 +0000To: Cassetti, Cristina (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston,Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [ElSubject: RE: Rapid instrument-free NAAT for COVID-19Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV _NIH.pdfSee attachment as per prior e-mai l.From: Fauci, Anthony (NIH/NIAID) [E)Sent: Friday, February 14, 2020 9:08 PMTo: Gary K. Schoolnik (b)(6)>Cc : Conrad, Patricia (NIH/NIAID) (El (b)(6h ; Barasch, Kimberly (NIH/NIAID) [CJ(b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger,---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E)---------- CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19Gary:Thanks for the note. I would be happy to discuss this with you. Please have your officecontact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient timewhen we can chat.Best regards,TonyFrom: Gary K. Schoolnik (b)(6)>Sent: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)>Cc: Adam de la Zerda (b)(6)Subject : Rapid instrument-free NAATfor COVID-19Dear Tony ,In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer ofVisby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection ofinfectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized,40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; it is used once,and then discarded or recycled . (b)(4)device is stable at room temperature for up to two years and thus it could be deployed widely.NIH-001874NIH-001875We are seriously considering using this platform to develop a rapid test to detect COVID-19.Proof of principles that have been achieved toward that end are our demonstration that thedevice can use two-step RT-PCR to detect influenza A and Bin NP swab samples. The mainfeatures of the device are described in the brief accompanying PDF.I write now because we are unsure, if we were to produce a COVID-19 device, how it would bedeployed, by whom it would be used and who might be willing to purchase it. I would be verygrateful if you might be able to speak briefly with me and my colleagues about these openquestions. I am convinced this device can meet a major unmet need in clinical care and diseasecontrol for this epidemic and we, as a group, want to make a difference. Your advice would beinvaluable as we weigh the risks and benefits of pivoting the company to this application.With all best wishes; I hope all is well with you and your family.garyGary Schoolnik, M.D.Professor of MedicineStanford Medical SchoolAttending Physician (Internal Medicine , Infectious Diseases)Stanford University HospitalChief Medical officerVisby MedicalFrom:Sent:To:(b)(6)Fri, 14 Feb 2020 18:45:53 -0500Julia BelluzSubject: Re: callMy pleasure!On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz <ju lia.belluz@vox.com>wrote :Thank you so much for making the time to comment at what I know is a crushinglybusy time. As usual don't hesitate to ping if you have any fmther comments orquestions! Juliahttps://wwv,,. vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singapore-ussymptoms-pan demicSent from my iPhoneOn Feb 14, 2020, at 1 :21 PM, Fauci, Anthony (NIH/NlAID) [E]Cb()6 ) wrote:Julia:I j ust called you now (7:20 AM Washington, DC time) andgot mvoice mail in German that I could not understand. Youcan call me at CbH6JThanks,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mai l: (b)(6)The information in this e-mail and any of its attachments is confidentialand may contain sensitive Information. It shou ld not be used by anyonewho is not the original intended recipient. If you have received this emailin error please inform the sender and delete it from your mailbox orNIH-001878NIH-001879any other storage devices . The National Institute of Allergy andInfectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender's own and not expressly made on behalf of theNIAID by one of its representatives.From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 21:09:40 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: RE: Your Expertise requested/COVID -19 ForumOK. Let us discuss. As long as it is remote ...Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Conrad, Patricia (NIH/NIAID) [El- ---------(b)(6) Sent: Friday, February 14, 2020 3:45 PMTo: NIAID OD AM <NIAIDODAM@niaid.nih.gov>Subject : FW: Your Expertise requested/COVID -19 ForumPatricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNat ional Institute of Allergy and Infectious DiseasesThe National Inst itutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be usedby anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not acceptliability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives.NIH-001880From: Roache, Christina (b)(6)>Sent: Friday, February 14, 2020 3:38 PM ------~~ TCoc:: CFaouncrai,d A, nPthaotrnicyi a (N(NIHIH/N/NIAIAIDID) ) [[EE]!] -.=-=-=--=-=-=-=(b-)~(6()b =)(6 )> Subject : Your Expertise requested/COVID-19 ForumDear Dr. Fauci,You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l ofPublic Health , and I wanted to see if you were available to participate remotely in a Fomm thatwe are organizing on March 2 about COVID -19.The Forum will live stream on the websites of The World and The Forum, as welJ as onFacebook and YouTube.The World will send a journa list to moderate and co-promot e.The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointlywith The World from PRX & WGBH.Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET onMarch 2; the actual live webcast will be noon-lpm ET.We have been active is cover ing this outbreak . We did a highly successfu l Facebo ok Live Q&Alast week and are doing another Q&A next week.As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4pane lists, plus a moderator. As noted, these discu ssions are live streamed from our LeadershipStudio at our school in front of a stud io audience (about 40 seats) and an online audience.Anyone with an Int ernet connection can watch the live webcasts; no registration or fee isrequired.NIH-001881Previous speakers in The Forum series have included Gina McCarthy , former EPAAdministrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S.Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services;Gordon Brown, former UK Prime Minister ; as well as numerous former governors and keypublic health policymakers and officials from a range of public and private sector entities.The Forum live webcasts are also streamed on The Forum website, where they areaccompanied by a live chat and online commenting, and on Facebook and YouTube. Thesewebcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube andiTunesU channels . We also make available podcasts, transcripts and other materials.Collective ly, the programs and complementary content have resulted in nearly five millionviewer engagements so far, and our website has received visits from more than 200 countries andterritories and every U.S. state.Please share your thoughts when you are able .Cheers,Christina RoacheAssociate Director, Production and Web, The Leadership StudioHarvard T.H. Chan School of Public Health(b)(6)NIH-001882From:Sent :To:Subject :Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 20:23:04 +0000Clayton , Janine (NIH/OD) [ElRE: Sex differences in COVID-19Not much at th is poi nt . ------------------------- (b) (5)Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Clayton, Janine (NIH/OD) [ElSent: Friday, February 14, 2020 3:06 PM(b)( >------ -:-::~ To: Fauci, Anthony (NIH/NIAID) [E]- ------- (b)(6) Subject : Sex differences in COVID-19Hi TonJanineNIH-001883(b) (5)From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 20:21:51 +0000Richard Allen JohnsonSubject: RE: 2020.02. 14 FridayDick:Thanks for the note. I certainly appreciate your concerns about WHO. Notmuch sleep for me lately. Just like internship.Best regards ,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From : Richard Allen Johnson (b)(6) ---------- Sent: Friday, February 14, 2020 3:18 PMTo: Fauci, Anthony (NIH/NIAID) [E) ,------- -(-b,..)_.c=. >; Richard Allen Johnson(b)(6)Subject : 2020.02.14 FridayHi, Tony,I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality oft hose of a thi rd world country . I only hope that they function bette r than their news updates suggest.They need a wo rld class public relations firm.I am deeply concerned re Covid-19 in India (with a population of 1500 million) and Africa (pop ulation100 million). News reports do not mention anything of th is pandemic wait ing to happen.Hope that you are well and gett ing a good night's rest.Best,DickNIH-001884From:Sent :To:Subj ect :Please han dle .Anthony S. Fauci , MDDirectorFauci, Anthony (NIH/NIAIO) [ElFri, 14 Feb 2020 18:27:24 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: inhaled buformin for coronavi rusNational Institute of Allergy and Infectious DiseasesBui lding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301) 496-4409E-mail : (b)(6l(b)(4)The information in this e-m ail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Steven Lehrer (b) (6) > ---------- Sent : Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El -------------- -C-b=H= >; Erbelding, Emily (NIH/NIAID) [E) (b) (6) >Subject : ------ (b)(4) for coronavirusDr. Fauci,(b) (4)Steven Lehrer, MD(b) (4)NIH-001887From: Fauci, Anthony (NIH/NIAIO) [E)Sent: Fri, 14 Feb 202017:39:33 +0000To: Routh, Jennifer (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy(NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E]Subject: RE: for review: proposed responses for Ital ian media requestNice Job. I have made one mino r edit in the fi rst response. Oth erwise, it is readyto go. Thanks.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Routh, Jennifer (NIH/NIAID) [E] (b)( >Sent: Friday, February 14, 2020 12:32 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E)(b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg(NIH/NIAID) [El (b)(6bSubject : for review: proposed responses for Italian media requestDr. Fauci -This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to youdirectly with questions about coronavirus vaccine development. I have drafted proposed responses foryour review attached and pasted below. I will send the final responses to the reporter attributed to you.Coronavirus vaccine: when will it be available? What are the diffi culties?The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in aPhase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine tohealthy adults in the United States to see if it is safe and if it can induce an immune response inrecip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinicaltesting to establish their safety and effectiveness takes t ime. A vaccine against the novel coronavirus willlikely not be widely available for at least a year.NIH-001890Could the Coronavirus mutate, if a vaccine cannot be found in time?We are learning more about the novel coronavirus every day. At this tim e, we are not awar e of anymutations that might affect vaccine development . Based on our exper ience with ot her coronav iruses,including SARS-CoV and MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus willmutate in a way that would have an impact on the development of medical countermeasur es. We areconti nuing to mon ito r this .Will the vaccine be the solution against Coronavirus?A safe and effective vaccine would be an extremely valuable tool to help stop the spread of in fectionand prevent future outbreaks. However, proven public health practices of ident ifying cases, isolatingpatients, and tracing contacts must continue alongside a vaccination program.Thanks,JenJennifer Routh [E]News and Science Writing BranchOffice of Communicatio ns and Government RelationsNational Institute of Allergy and Infectious Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda, MD 20892Direct: (b) ~Di sclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not beused by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. The National Institute of Alle rgy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives.NIH-00189 1From:Sent :To:Fauci, Anthony (NIH/NIAIO) [ElFri, 14 Feb 202017:23:43 +0000Cassetti, Cristina (NIH/NIAID) [E]Subject: FW: (b)( 4)Please han dle. Thanks.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Hardham, John M -----------(b)(6)> Sent : Friday, February 14, 2020 9:15 AM -------::-::-=, To: Fauci, Anthony {NIH/NIAID) [El- ------- (b)((;)> Subject: (b) (4Tony:It was good to see you again at the ASM Biothreats Conference. We had worked together on theMedical Countermeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program(under ASD Andrew Weber) several years ago.If you or your staff have any interest, please feel free to reach out to me.Hope you have a wonderful day !JohnNIH-001892(b) (4)John M. Hardham, Ph.D. I Research Director , Global Biologics ResearchDirector , Zoetis Center for Transboundary and Emerging DiseasesZoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007Office : (b)(6) I Mobile (b)(6) I (b)(6)Visit Us: zoetis .comzgetis Erne ectious DiseasesFORANIMFOAHlRSE . AlJFHO.YR O U. -- First cok now . Fastt om arketNIH-001893From:Sent:To:Cc:(NIH/NIAID) [E]Subject:(b) (4)Nicole:Fauci, Anthony (NIH/ NIAID) [E)Fri, 14 Feb 2020 15:52:49 +0000Strauss, NicoleMascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, PatriciaRE:- --------------------- (b) (4) IThank you for your note and interest. I will copy on this e-mai l Ors. JohnMascola and Barney Graham of our Vaccine Research Center who are developingthe vaccine with Moderna so that they can respond directly to you.Best regards ,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: Cb()6 JFAX : (301 496-4409E-mail : (b)(6JThe information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Strauss, Nicole ---------- (b)(Sent : Friday, February 14, 2020 10:37 AM ------~~ To: Fauci, Anthony .(,;N..I.H__/N;__I A ID). :.[..E.].. :....:..:::===-;:;;::;----(b)(6JCc: Weisser, Karen (b)(6JSubject : _____________________ C_>b_C4_), I ___ C>b_C4_)Dear Dr. Anthony Fauci,(b) (4)NIH-001894Best regards,Nicole• CentreOneNicole StraussPipeline Development & Innovat ion LeadT: (b)(6) I M: (b)(6)500 Arcola Road, Collegeville, PA 19426Website I LinkedlnNIH-001895From: Fauci, Anthony (NIH/NIAIO) [E)Sent :To: (b)(6)Fri, 14 Feb 2020 14:22:00 +0000Greg Folkers ---------- Subj ect : NEJMAttac hment s: NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdfHere it is.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBui lding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sen sitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.NIH-001896From: Fauci, Anthony (NIH/NIAID) [ElFri, 14 Feb 2020 03:20:06 +0000Embry, Alan (NIH/N IAID) [ElConrad, Patricia (NIH/NIAID) [ElSent:To:Cc:Subject: RE: Instit utional request for informationThanks, Alan.From: Embry, Alan (NIH/NIAID ) [E] ______ Cb_H_6)Sent : Thursday, February 13, 20 20 10 :18 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------ (=b)""('6=)>; Fried, Linda P.----------- (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , LeeCb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. ~========-.,;-- (b )( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert"('!N"-'IH- /':N""-IA-1- 0-:)--[:E--): -:::::::=====-_;,_-- ~(b")("=6")'Subject : RE: Institutional request for informationDear Dr. Fried,Answers to your questions are below .1. Is the CDC or NIH overseeing the distrib ution of the live virus in the U.S.?There is an interagency working group convened by the Assistant Secretary for Preparedness andResponse oversee ing samples, and NIH and CDC are central to this . Virus is being deposited in BEiResources (a NIAID contract resource) for characterization, growth and distrib ution. The WA isolateis available now and a Hong Kong isolate may be added soon.2. Will you be the sole source of dist ribution in the U.S., or will institut ions be permitte d to obtain itdirectly from oth er sources?Assuming appropriate permits are in place, there is no limitation on an institution obtaining samplesdirectly from BEi or other sources. In a public health emergency, the U.S. government seeks to makeisolates availab le under a Simple Letter Agreement that does not impose IP restrictions onacademics or developers (see attached language).3. If it can be obt ained from other sources, wh at sources will be permitt ed? For example, the Chinaor Hong Kong CDC or University of Hong Kong?Assuming appropriate permits and safety controls, there is no limitation on from where samples canbe obt ained . However, there may be intellectual property restrictions from some sources and yourtechnology transfer office would need to negotiate if requested directly.4. If you are to be the sole source, w hen would you expect to have a process for consideringrequests?BEi resources already has a process for sharing in place and is currently sharing the vira l isolateobtained from the first Washington case. NIAID ant icipates that other viral isolates will be obtainedsoon, and BEi is committed to making those available to the scientif ic community as soon asNIH-001897possible. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the mainsources for this research resource based on experience with Zika.S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions otherthan the self isolation/quarantine already in place (and of course subject to change over time)?For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For highconsequence viruses, use of proper PPE has been a mitigating factor in quarantine consideration.Please feel free to contact me if you have additional questions.Thanks,AlanAlan Embry, Ph.D.Chief, Respiratory Diseases BranchDivision of Microbiology and Infectious Diseases, NIAID, NIH5601 Fishers Lane, Room 8E31Rockville, MD 20892(b)(6)(b)(6)From: Fauci, Anthony {NIH/NIAID) [E] -------- (b)(6) Sent: Thursday, February 13, 2020 6:35 PMTo: Fried, Linda P. (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6)>Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee(b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ "."--.--.-:--:~==~(.b..):(6..),>_; -M-a~rs=to n , Hilary {NIH/NIAID) [E] CbH6l>E; mbry, Alan(NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] CbH6J>Subject: RE: Institutional request for informationLinda:There is a "sample sharing" working group involving NIH and CDC. I havecopied both Hilary Marston and Alan Embry from NIAID who are involved in thisgroup and will ask them by this e-mail to respond to items #1 through 4.Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province)within previous 14 days, they submit to institutional quarantine ; if in non-Hubeiprovince part of China, then they face self-isolation.Hope that this is helpful.Best regards,TonyNIH-001898Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBui lding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Fried, Linda P. (b)(6)Sent : Thursday, February 13, 2020 12:45 PMTo: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E](b)(6)Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (=b)=(=;.;. =Go=ldman, Lee(b)(6)>; Booth, Jane (b)(6)>; Katznelson, Ira I.======== (;b;:):;:(c6~)Subject : Institutional request for informationDear Ors. Redfield and Fauci,I am writing on behalf of Columbia University, which has received a request from Dr. Ian Lipkin totrans fer live novel coronav irus from Hong Kong to his BSL3 facility at the Univers ity. As we evaluate hisrequest , we note that he has approval from a CDC official to import the virus (see attached). However,as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you:1. Is the CDC or NIH overseeing the distribution of the live virus in the U.S.?2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtainit directly from other sources?3. If it can be obtained from other sources, what sources will be permitted? For example, theChina or Hong Kong CDC or University of Hong Kong?4. If you are to be the sole source, when wou ld you expect to have a process for consideringrequests?5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictionsother than the self isolation/qu arantine already in place (and of course subject to change overt ime)?Thank you ve ry much fo r your help with these important questions as we all try to do our best tocontribute solutions to this health crisis.With best regards,LindaNIH-001899NIH-001900Linda P. Fried, M.D., M.P.H.Dean and Delamar Professor of Public HealthProfessor of EpidemiologyMai lman School of Public HealthProfessor of Medicine, Vagelos College of Physicians and SurgeonsSenior Vice President, Columbia University Irving Medical CenterColumbia UniversityFrom: Fauci, Anthony (NIH/NIAIO) [E)Sent : Fri, 14 Feb 2020 03:00:23 +0000To: Mansoura, Monique K.Cc: Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E)Subject: RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT'sProfessor Andrew LoThanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) andshe can then brief me on it.Best,TonyFrom: Mansoura, Monique K. (b)( '>Sent : Thursday, February 13, 2020 10:36 AMTo: Fauci, Anthony (NIH/NIAID) [E] ----- -- (b,.).(.=6)Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)>Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew LoDr. Fauci,The nation again is fortunate to have your leadership for this latest public health emergency . Thank youfor all you are doing. r know you are extraordinari ly busy, so I'll be brief.I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who hasfocused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1have worked with him to explore financial engineering approaches to estab lish more durable public-privatepartnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Instituteevent this week resonate loudly with Andrew and me.He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tberinformation.Respectfully,MoniqueMON IQUE K. MANSOURA, PH.D., M.B .A .Executive Director, Global Health security and Biotechno logyThe MITRE Corpo ration202 Burl ington Road I Bedford, MA I 01730-1420Office: (b) (6)(b)(6)The MITRE Corporation is a not-for-profit organization that operates federally funded research anddevelopment centers for the United States government.NIH-001901From:Sent :To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 02:56:17 +0000Greg Folkers (b)(6))FW: FYI -- images of SARS-CoV-2 now upLet us make some power point slides from these. Thanks.From: Billet, Courtney (NIH/NIAID) [E) -------- (b) ~ > Se nt: Thursday, February 13, 2020 1:22 PMTo: NIAID OD AM <NIAIDODAM@niaid.nih .gov>Subject: FYI -- images of SARS-CoV-2 now uphttps://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-imageshttps://www.flickr .com/photos/niaid/albums/721 57712 9 14621487NIH-001902From:Sent :To:Cc:Subject:Patty: Let us discuss.Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 02:42:53 +0000Conrad, Patricia (NIH/NIAID) [E)Greg Folkers (b) ( ·)FW: PBS'S FIRING LINE REQUEST// DR. ANTHONY S. FAUCIGreg: Are they a big dea l?From: Melanie Starling <melanie@thedocumentarygroup .com>Se nt: Thursday, February 13, 2020 6:39 PMTo: NIAID NEWS (NIH/N IAID) <NIAIDNEWS@niaid.nih.gov>; Fauci, Anthony (NIH/NIAID) [E)(b)(6)Subject: PBS'S FIRING LINE REQUEST // DR. ANTHONY S. FAUCIImport ance: HighGood Evening,Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER .Due to a last minute cancellation, we are crashing on a deadline and need to know if he is ableto jo in us ASAP.I look forward to hear ing your thoughts and all best ,MelanieMelan ie StarlingFiring Line with Margaret HooverCell: (b)(6)Email: melanie@thedocumen t arygroup .com___. ------- --Fl RI n G LlnEW ith MA RGARET HOOVERGood Evening,NIH-001906NIH-001907This is Melanie Starling writing on behalf of PBS'S FIRING LINE WITH MARGARET HOOVER.FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnestexchange of ideas, with the luxury to let the conversation breathe. Margaret has brought backthe spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today'spolarized cable news ecosystem - at a time when we need it more than ever. One guest. 30minutes. Airing to a thoughtful and engaged PBS audience.We would be honored to have Dr. Anthony S. Fauci join Firing Line for aninterview.Dr. Fauci has dedicated his career to understanding, preventing, and protecting people acrossthe globe from infectious diseases, which is why we would be so honored to share our stagewith him at this time. As the coronavirus continues to spread, we are interested in betterunderstanding the deadly virus the world is racing to contain. Equally, we are interested inhighlighting any other public health issues or policies close to Dr. Fauci's heart. Mostimportantly, with our program, we have the luxury of time-where we can truly delve intothese issues in a substantive, nuanced manner that is missing in much of today's 24-hour newscycle.THE DETAILS FOR TAPINGTAPE DATE: TARGETING FEBRUARY 19TH - EVENING TAPING IS PREFEREDTAPE TIME: 45 MINUTESLOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER)TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST.f lRING LINE is carr ied nationwide on PBS with 99% market pick-up, and is suggestedprogramming for PBS's 8:30 PM ET on Friday nights with multiple airings through the week. OnTwitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBS remains acoveted home for intellectual, elevated programming- and stands out as a top 5 outlet toreach persuadable voters.HIGHLIGHT REELFIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group.Please reach out to me if there is any interest . We will bend over backwards to get it done.Thank you in advance for your consideration, and please feel free to reach out to me 24/7 withquestions or concerns.All the best,MelanieMelanie StarlingFiring Line with Margaret HooverCell: (b)(6)Email: melanie@ t hedocumentarygroup.comABOUT FIRING LINE WITH MARGARET HOOVERFiring Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBSprogram, a smart, civil and engaging contest of ideas. The series maintains the character of theoriginal, providing a platform that is diligent in its commitment to civility and the rigorousexchange of opinion. Firing Line with Margaret Hoover comes at a time when meaningfu ldiscourse is needed more than ever. Interviews and debates will highlight leading lights fromthe left and right, complemented by archiva l footage from the original Firing Line to rem indviewers of longstanding conservat ive and liberal arguments, where they've been disproved orreinforced over time. It is an opportunity to engage in the debate about the America tha t wewant to create for the 21st centu ry - and summon Americans of every politica l persuasion to arigorous examination of the choices we must make together in the challenging years ahead.Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff.ABOUT MARGARET HOOVERMargaret Hoover is an American political commentator . In addition, she is also an author,fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN.HIGHLIGHTS ON FIRING LINE WITH MARGARET HOOVERSpeaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. JohnKasich, Gov. Scott Walker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA),Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, PeterNavarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, AnnCoulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. PramilaJayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, MichaelBloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA)Melanie StarlingPBS's Firing Line with Margaret HooverCell: Cb) (6)Email: melanie@thedocumentaryqroup.com- ---- - FIRlnG LlnENIH-001908From: Fauci, Anthony (NIH/NIAID) [E)Sent: Fri, 14 Feb 2020 02:36:46 +0000To: ncalio@airlines.orgCc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty(C0C/0010/NCEZID/DGMQ)Subject: FW: Coronavirus Task ForceAttachments: Fauci A4A Letter to Coronavirus Task Force .pdfNick:Many thanks for sending this. The CDC would be very interested in your willingness to movein the d irection of having complete contact information on passengers available to them. I amcopying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e-mai l. I amsure that one of them will contact you about this issue.Best regards,TonyFrom: Calio, Nicholas <ncalio@airlines.org>Sent: Thursday, February 13, 2020 8:18 PMTo: Fauci, Anthony (NIH/NIAID) [E]--------=- (b):-(-=6: )>Subject: Coronavirus Task ForceDear Dr. Fauci,Please see the attached letter.Thank you,Nick CalioNIH-001909From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 14 Feb 2020 02:09:44 +0000Conrad, Patricia (NIH/NIAID) [ElSubject: RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop)Tell them that I turned down the same invitation and he should turn it down also. It is not amajor eventFrom: Conrad, Patricia (NIH/NIAID) [E]- --------- (b)(6) Sent: Thursday, February 13, 2020 8:21 AMTo: Fauci, Anthony (NIH/NIAID) [El ------~~Cc: Folkers, Greg (NIH/NIAID) [El ,..;.::=======:,;,~ --------- Subject : FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop)Please see below . You were invited to this - it was discussed in our daily meet ingand we decided to decline it for you. we did decline it. would you recommend thesame as they are now asking Dr Collins.Pis advise.Patricia L. ConradPublic Health Analyst andSpec ial Assistant to the DirectorNat ional Institute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaime r:The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be usedby anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not acceptliabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives.From: Harris, Kara (NIH/NIAID) [El -------- (b)(6)>Sent : Wednesday, February 12, 2020 4:18 PM -------~~ To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>Cc: Billet, Courtney (NIH/N IAID) [E)· .=.====~ (b~)~(6)~>-; ~Haskins, Melinda (NIH/NIAID) [E](b)(6)Subject : Invitation : 388393 Santos (Coronavirus Preparedness Workshop)NIH-001910NIH-001911Hi, Patty -Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation tospeak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June inWashington, DC. The conference is being organized by Syllabusx, a group of "international specialists inpublic health and emergency planning events and disaster recovery conferences ."Given the nature of the conference topics, do you concur with recommending Dr. Collins decline theinvitation and refer to CDC?Thanks for your input.KaraFrom:Sent:To:Cc:Subject:Alison:Fauci, Anthony (NIH/NIAIO) [E)Thu, 13 Feb 2020 23:22:27 +0000Alison GalvaniConrad, Patricia (NIH/NIAID) [E]RE: Lancet special issue proposalThanks for the note . I really appreciate your kind invitation, but unfortunately, Iwill have to decline. My plate is already overflowing and I just cannot take onany additional editorial responsibilities . In addition, I am swamped withcoronavirus "stuff" that is not going to end soon. I hope that you understand .Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail Cb) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Alison Galvani (b) (6)Sent: Wednesday, February 12, 2020 2:28 PM ------ ..-.-,= To: Fauci, Anthony (NIH/NIAID) [E] CbH >Subject: Lancet special issue proposalHi Tony,I hope you are well.(b) (4)Thank you so much for your consideration.NIH-001912Warmest regards,AlisonAlison Galvani, PhDDirector, Yale Center for Infectious Disease Modeling and Analysis (CIDMA)Burnett and Stender Families Professor of EpidemiologyYale School of Public HealthYale School of MedicineNew Haven, CT 06520(b)(6)htt p://c idma .yale .edu/NIH-0019 13From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Thu, 13 Feb 2020 23:10:07 +0000Conrad, Patricia (NIH/NIAID) [ElFW: Personal connectionPlease set this up (5 minutes) for Monday.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Conrad, Patricia (NIH/NIAID) [El- -------- (b)(6)] Sent: Wednesday, February 12, 2020 8:58 AM -------=-,-:-= To: Fauci, Anthony (NIH/NIAID) [El- ------- (b)(6) Subject : FW: Personal connectionThis guy called last night and seemed to know you - let me know if and where youwant me to direct him.Or maybe do a call with you on a quieter day - Monday on Pres day holiday?Patricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaime r:NIH-001914The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be usedby anyone who is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not acceptliability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives .From: Banner, Jon {PEP} (b)(6)>Sent: Tuesday, February 11, 2020 9:44 PMTo: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] ----------- (b)(6)Subject: Personal connectionDear Dr. Fauci,Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer ofWorld News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also ExecutiveProducer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Backthen, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and deathissues of our time, and your input was of enormous value to our viewers and the general public.Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . Iwas hoping you could help us identify an expert to provide similar insight and analysis for our companyas we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel,I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want to take up toomuch of your time.If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeplyappreciate it if you could connect me with another expert over email.Thanks very much, and hope you are doing well!Warm regards,JonNIH-001915From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Thu, 13 Feb 2020 22:47:23 +0000Eisinger, Robert (NIH/NIAID) [E]Subject:Attachment s:FW: Institutional request for informationCll 2020 CDC import permit .pdfAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sen sitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Fried, Linda P. (b)(6)Sent : Thursday, February 13, 2020 12:45 PMTo: Redfield, Robert R. (CDC/OD) (b)(6) Fauci, Anthony (NIH/NIAID) [E](b)(6)Cc: Conrad, Patricia (NIH/NIA ID) [E] ----======(~b)(6~) >~; G oldman, Lee (b)(6); Booth, Jane ________ CbH_ ; Katznelson, Ira I.======== (~b)~(6;;)--Subject: Institutional request for informationDear Ors. Redfield and Fauci,I am writing on behalf of Columbia University, which has received a request from Dr. Ian Lipkin totransfer live novel coronav irus from Hong Kong to his BSL3 facility at the Univers ity. As we evaluate hisrequest , we note that he has approval from a CDC official to import the virus (see attached) . However,as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you:1. Is the CDC or NIH overseeing the distribution of the live virus in the U.S.?2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtainit directly from other sources?3. If it can be obtained from other sources, what sources will be permitted? For example, theChina or Hong Kong CDC or University of Hong Kong?4. If you are to be the sole source, when wou ld you expect to have a process for consideringrequests?NIH-0019 16NIH-0019175. If someone wishes to travel to China to work on the live virus, are there any travel restrictionsother than the self isolation/quarantine already in place (and of course subject to change overtime)?Thank you very much for your help with these important questions as we all try to do our best tocontribute solutions to this health crisis.With best regards,LindaLinda P. Fried, M.D., M.P.H.Dean and Delamar Professor of Public HealthProfessor of EpidemiologyMailman School of Public HealthProfessor of Medicine, Vagelos College of Physicians and SurgeonsSenior Vice President, Columbia University Irving Medical CenterColumbia UniversityFrom: Fauci, Anthony (NIH/NIAIO) [E)Sent : Thu, 13 Feb 2020 22:44:12 +0000To: Stoffels, Paul [JJCUS]Cc: Riccobene, Kim [JJCUS];Van Hoof, Johan [JRDBE);Conrad, Patricia (NIH/NIAID)[E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID)[E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E]Subject : RE: COVID-19 vaccine developmentPaul:Thanks for the note. I will have Patty Conrad {copied here) try to worksomething out for Feb.21 st. My schedule is at the mercy of the White House andthe Congress and so I cannot guarantee anything right now.Best Regards,TonyAnthony S. Fauci , MDDirecto rNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail (b)(6)The information in this e-ma il and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expre ssly made onbehalf of the NIAID by one of its representatives .From: Stoffels, Paul [JJCUS-] ------ (b)(6)>Sent : Thursday, February 13, 2020 9:42 AMTo: Fauci, Anthony (NIH/NIAID) [E) ----- --(:b=aH=6)>Cc : Riccobene, Kim [JJCUS-) ------- (b)(6); Van Hoof, Johan [JRDBE)- ------- (b)(6)>Subject : COVID-19 vaccine developmentDear Tony,Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine.(b) (4)NIH-001918If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, Iwould much very appreciate .(b) (4)Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I willbe in Europe till the 19th .Best regards,PaulPaul Stoffels, MDVice Chairman & CSOJohnson & Johnson(b)(6) (Mobi le Europe)(Office US)NIH-001919From:Sent:To:Subject:Fauci, Anthony (NIH/NIAID) [E)Thu, 13 Feb 2020 03:16:08 +0000Barasch, Kimberly (NIH/NIAID) [C)FW: Run of show- 2/13, 9-l0am White House Roundtable on COVID-19Make sure that this is in my folder.From:S elgrade, Sara (NIH/NIA ID) [El- ------- (b)(6}> Sent: Wed nesday, February 12, 2020 3:16 PM -----~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)Cc: NIAID OCGR Leg <NIAIDOCGRLeg@mail.nih.gov>; Conrad, Patr icia (NIH/NIAID) [El(b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet,Courtney (NIH/N IAID) [E] (b)(6)Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19Dr. Fauci,Please see below for information we have received from HHS thus far regardingtomorrow's briefing on coronavirus at the White House. Patty has submitted yourinf onnation via the WA YES link for the event. We are checking with HHS ASLto make sure your clearance has been proce ssed.We will share any additional information as we receive it. Please let me know ifyou have any questions.Thanks,SaraWhite Hou se Congressional Roundtable on CoronavirusDate: Thursday, February 13Time: 9:00 - I 0:00 a.m.Location: Roosevelt RoomRun of show:• Acting Chief of Staff Mulvaney will open the proceedings and briefly frameall that we are doing and why we have asked the Members to assemble (togain their insight and to seek their wisdom).NIH-001923NIH-001924• Anne Schuchat will give a brief overview of current status and materialissues.• Anthony Fauci will give a brief explanation of our understanding of thevirus and development of countermeasures.• Brig Gen. Paul Friedrichs of DoD will provide a brief status report on forceprotection.• Acting Chief of Staff Mulvaney will open the floor for questions andmoderate the proceedings - possible that White House legislative affairs willstand in here (Eric Ueland or Mike McKenna).Expected participant s:Members (confirmed RSVPs thus far)Senator James RischLeader McCarthyRep. Kay GrangerRep. Greg WaldenRep. Nita LoweyBriefersDHS-Alex ZemekCDC- Dr. Anne SchuchatNIAID-Dr. Tony FauciASPR- Dr . Bob KadlecFDA-Dr. Steve HahnDHS - Ken CuccinelliNSC - Anthony RiggieroNSC - Matt PottingerState - Stephen Biegun (tentative)DOD - Brig Gen. Paul FriedrichsFrom:Sent :To:(b)(6)Wed, 12 Feb 2020 11:02:30 -0500John LauermanSubject : Re: InterviewI tried calling but the call would not go throughOn Feb 12, 2020 , at 6: 15 AM, John Lauerman (BLOOMB ERG/ NEWSROOM:)<jlauemmn @bloomb erg .net>wro te:Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of majordrugmakers stepping up to make coron av irus vaccine , a nd mycolleague James Paton is working on a story about that issue .J ames ' s story has to do with a bi osecurity initia t ive related tothese types of t hreats at GSK tha t was started in 2016 and quicklypu t on t he bac k bu r ner . I do n 't know whe t h e r you 'd want t o commen ton the company or its activities i tse lf , bu t wou ld b e he l pfu l ifyou could talk about t he im p ortance of ge ttin g big drugmakersinvolve d in helping t o fill t he need f or new vaccin es . I 'm inGeneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe wecan t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp ,where my number i s (b)(6). Ple ase let me know if/whenyou ' re free . Thanks and regards , JLFrom : John La uerman (BLOOMBERG/ NEWSROOM: ) At : 02/07/20 15 :53 :34To : (b)(6)Sub j ect : RE : Int erv i ewUnder stood . Hope you ge t a chanc e to r es tFrom : a f auci@niaid . nih .g ov At : 02/07/20 15 : 51 : 39To : J ohn Laue r man (BLOOMBERG/ NEWSROOM: )Sub jec t : RE: InterviewSorry John. I am totally tied up right now and besides, Iam completely hoarse and can barely speak. Let us trysome other time.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)NIH-001925FAX : (301) 496-4409E-mail: Cb) (6)The information in this e-mail and any of its attachments is confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intended recipient . If you have received this emailin error please inform the sender and delete it from your mailbox orany other storage devices . The National Institute of Allergy andInfe ctious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender 's own and not expressly made on behalf of theNIAID by one of its representatives.From: John Lauerman (BLOOMBERG/ NEWSROOM :)<jlauerman@bloomberg .net>Sent : Monday, February 3, 2020 8:1-8- A-M-- -~~ To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6)Subje ct: InterviewHi Dr . Fauci : How are you? I 'm wri t ing t o seewhether we can talk again fo r a few minutes.We' r e worki ng on a b i gg i sh p iece abou t t hel arger b i o-secur i t y i ssue wor l dwi de a nd wh a t t hecoronavi r u s outbreak tells u s abo ut it . What canwe do abou t t he weakes t lin ks in d i sease co nt ro lin p oore r n a t ion s in Af r ic a , Asia a nd e l sew here?The WHO today bro ug ht up the impo r tance ofaccess to health care along with spending onp ub li c h ea l t h, a nd c l ear l y t hi s i s a n issue inpoo r co un ties . Is it also important ininfectio us disease in the US and if so, is itad e qua t ely recognized? Compa nie s a nd researchcenters have made h ug e strides in qu ickdevelopment of vaccines and dr ug s ; what can takei t t o t he nex t level? Is t he r e a ny t hing t ha tco ul d be done to attract more companies to thisfield? What kind of n ew t e chnologi e s can help ust rack ne w v i ruses in t he communi t y? I ' ve bee nt a l kin g wi t h peop le using ha ndhel d n ano por eseq uence r s to track coronavi r u s and Ebola ; whatel se i s ou t t here? Do we nee d t o do a b e tt er jobof t racking t he move men t of peop le a nd goods?Also glad to get any other observations . Pleasec a l l t oday or t omorrow mornin g at ~o r le t me know when a nd a t wh a t (number to call you . Thanks and re g ards , lookforward t o he ar in g from you , JLNIH-001926John Lauerman, Bloomberg News3 Queen Victoria Street, Lond-o-n-, -U-K- --=--=-:= tel. +44 (0) 2035 251028 cell --------- Cb)(6) http ://www .bloombe rg.comhttp://www .bloomberg.com/prog nos isNIH-001927From: (b)(6)Sent : Wed, 12 Feb 2020 10:24:06 -0500To: Daniel LuceySubject: Re: Update IDSA Science Speaks post today# 10: PPE mass production andPOlyclonal/mAbs Rx PReP and PEPThanks danOn Feb 12, 2020, at 9:34 AM, Daniel Lucey Cb) (6)>wrote: ---------Bob K., Tony and Bob (Redfield),Given the news of health care personnel in Wuhan and Hubei being infected, andacute shortage of PPE for COVID-19, I posted these Q&A s on the ID SocietyAmerica "Science Speaks" website as the 10th in a series of my updates sinceJanuary 6th.The final Question asks and answers that mass production of COVID-19 PPEshould occur now.DanHong Kong Feb. 12, 2020bttps ://sciencespeaksblog. org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for- treatmen t-and -prophylax is/NIH-001928From:Sent:To:Cc:Fauci, Anthony (NIH/NIAID) [E)Wed, 12 Feb 2020 15:23:15 +0000Folkers, Greg (NIH/NIAID) [E)Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C]!';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meetingat the Ritz Carlton (22nd and M St. NW), Washington, D.C.Attach ment s: image003.jpg, image004.jpg, imageOOS.jpgOkay. Go with itOn Feb 12, 2020, at 9:38 AM, Folkers, Greg (NIH/NIAID) [E](b)(6) wrote:Will addI would vote fo r: no slides-I would send these three papers (all on director's page) - CoV, Ebola, Ending HIV<image003 .jpg>Foreign Policy<image004 .jpg><image005 .jpg>From: Conrad, Patricia (NIH/NIAJD) [E)- -------- (b)(6) Sent : Wednesday, February 12, 2020 9:11 AMTo: Folkers, Greg (NIH/NIA ID) [El ~======'~~ Cc: Fauci, Anthony (NIH/NIAID) [El _______ C_b<>.; Barasch, Kimber ly (NIH/NIAID)[CJ (b)(6)Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting atthe Ritz Carlton (22nd and M St. NW), Washington, D.C.Kim - pis add all to the folder thxNIH-001929G - this needs to be added to matrix. IT was a "fires ide chat" that wethought would not include slides but see below -they are ok with afew slidesWill need to discuss things to send and topics given the "theme"Patricia L. Con radPublic Health Analyst andSpecial Assistant to the DirectorNation al Inst itute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Mary land 20892(b)(6)301-496-4409 faxDisclaime r:The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. Itshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergyand Infectious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and notexpress ly made on behalf of the NIAID by one of its representatives.From: Marlene Colucci <mcolucci@businesscouncil.com>Sent: Tuesday, February 11, 2020 6:29 PMTo: Conrad, Patricia (NIH/NIAID) [El --------=- (bs)-( =6)Cc: Adrienne Ball <aball@businesscouncil.com>; Gillian Auger<gauger@businesscouncil.com>Subject: Re: Business Council - Invitation to speak at the February 20-21, 2020 meeting atthe Ritz Carlton (22nd and M St. NW), Washington , D.C.Patty,I wanted to check back with you and Dr. Fauci on a few things in advance of his firesidechat with David Rubenstein on Friday, February 21.• Are there any art icles that Dr. Fauci thinks would be useful to send out to our CEOsin advance of the discussion (it may be something related to the Coronavirus orsomething that looks at the future of health and what CEOs should be thinkingabout in the next decade?NIH-001930• The theme for our upcoming meeting is "The Next Decade - Major trends intechnology, geopolitics, politics, economy and health" . I have attached a copy ofour Draft CONFIDENTIAL and list of attendees for Dr. Fauci's reference .• During his discussion with David Rubenstein, are there any slides he would like touse for reference? We do not use a lot of these but thought there might be slidesthat wou ld aid in his discussion? Just let us know.Warmest regards,MarleneMarlene ColucciEXECUTIVEDIRECTOR'I BUSI TESS~ l0L 1\.C.L ..T: 202-298-7650C: (b)(6)F: 202-785-0296On Feb 5, 2020, at 9:19 AM, Marlene Colucci<mcolucci@businesscouncil.com> wrote:Thank you Patty for checking. As soon as I can find out whether Dr. Collinswi ll also be a part of the discussion I will work on setting up t hat call. Ivebeen pressing their office so fingers crossed!MarleneMarlene ColucciEXECUTIVEDIRECTOR"I BUSINESS~ COL.:\JCILT : 202-298-7650C: (b)( 6)F: 202-785-0296NIH-001931On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E]---------- (b)( wrote:Good morni ng:Dr. Fauci will not be able to att end the dinner thenight befor e but wanted me to thank you fort hink ing of him.Best,-patt yFrom : Marlene Colucci <mcolucci@businesscouncil.com >Sent: Friday, January 31, 2020 2:00 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------ .(-b..H..,=6JCc: Conrad, Patricia (NIH/NIAID) [E] CbH6; JDavid Rubenstein (b)( ; MaryPatDecker ------------ (b)(6) Subject : Business Council - Invitat ion to speak at the February20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW),Washington , D.C.Dear Dr. Fauci,On behalf of our co-chairs for the winte r meeting of TheBusiness Council, David Rubenstein of The Carlyle Group andGinni Rometty of IBM, we wou ld like to formally invite you toparticipate in our meeting on February 20-21, 2020 inWashington, D.C. The theme of the meeting is "The NextDecade." (See formal invitation attached as well as list of CEOmembers).We would like for you to participate in a 50 minute fireside chatwith David Rubenstein (and possibly Dr. Francis Collins) todiscuss the current coronavirus as well as what we shouldexpect in the next decade. We want to give our CEOs insightsinto what the next 10 years will bring in terms of detection,diagnosis and treatment of diseases. All conversations arestrictly off the record and closed press. We wil l cover all lodgingand transportation.As you know, The Business Council is comprised of the chiefexecutive officers of the largest global corporations,representing all segments of the economy . We expect at least150 CEO members, spouses and speakers to be in attendance.NIH-001932As a participant you and your spouse are also invited to join usfor our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is thebest opportunity for you to meet our CEO members andspouses, speakers and other special guests in an informalatmosphere.If you are interested and available, please let me know. We canalso set up a very brief call with you to discuss any additiona ldetails and answer any questions you may have. We lookforward to hearing from you and would be honored to have youparticipate wit h us again.Warmest regards,MarleneMarlene ColucciEXECUT IVEDIRECTOR~ BUSINESS ·11• ~ COL '!CTLT : 202 -298-7650C: (b)(6)F : 202- 785-0296i:@H@Vit3w0\4.2c5.t.a7t.a nso Al!ll1etric 2109Vl~wpointJanuary 23. 2020Coronavirus Infections-More Than Just theCommon Colde,,11.. w, P""""'-1o1•0 .•. ..,.,0 """"°"·"°'..,,,.,f,.1.W,,.l,.fll>l1o oy~ ,....,,.,,...I, ."f"".'-il.~,1-t!o<,.,.,..,/Ml,\. P\.ll»ihNl<.>. nSl ,,,--, l).10/0, cir, IQ 1001/1,oN.JQX)flmNIH-001933AI\OUl'!fNIOn the Front Lines of the TrumpAdministration's Ebola ResponseThe IJnilal S\.11ClS\. '15m ounlOOn wide ~ (t,JlOO.SC\t0h e~ <l.ool)•ou1bfc:l.l,;."o-1n fy ~on.Ending the Human Immunodeficiency VirusPandemic: Optimizing the Prevention andTreatment Toolkit s oClinicoJ f11k<.~ Di~.>e~, Volu1TW69' , b,ue 11, LS De<.e,nbt-r2 0 tt. P•g~ 1n :>-2>l 1,.,UJ>~/irtn, MY ICJ IC"~ilffd/c ,,,,.lHPubUJhed: 24Octobet2019 Arlk le hlstory •NIH-001934NIH-0019351/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09ViewpointJanuary 23, 2020Coronavirus Infections-More Than Just theCommon Coldc..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W>A11thofAf1f1,,f1'0f1I'\ M-.1l"~f ~ •tton"'-'" ~- -13.1010. dol 10100t/!,,m,ll0 l001'>1NIH-001936ARGUNCTNOn the Front Lines of the TrumpAdministration's Ebola ResponseThe t:nitcdS latest i,., mounteda wide r.mgiQgr cspoo.<toe t he btelt dc:>dl)'o utbrc-'o1s1 o<n. ly~can.NIH-001937Ending the Human Immunodeficiency VirusPandemic: Optimizing the Prevention andTreatment Toolkit s oC/inicollnf«IX>U1 D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117,I tlJ)';//dol.org/ l O.lO'J]/cid1<1t' :ISPubtiffled: 24 Oelobet 2019 Artkle history •NIH-001938From:Sent:To:Cc:Subject:Fauci, Anthony (NIH/NIAID) [ElWed, 12 Feb 2020 12:04:55 +0000Cassetti, Cristina (NIH/NIAID) [ElConrad, Patricia (NIH/NIAID) [ElFW: epiqar for Coronavirus assistancePlease handle. Thanks.From: Daniel Goldberg <daniel@eng.us>Sent: Tuesday, February 11, 2020 11:18 PMTo: Fauci, Anthony (NIH/NIAID) [El <afauci@niaid.nih.gov>Subject: epiqar for Coronavirus assistanceDr. Fauci,I wanted to reach out to see if epiqar (https://ep iqar.com/) can help your efforts with theCoronavirus- we are the only system in the world built for remote surgical help & interactiveemergency surgeon support over the web browser.epiqar has created the most advanced surgical video collaboration technology, allowingsurgeons to consult and train remotely on a low-cost and easy-to-use online surgicalcollaboration platform and Cloud-archiving system built for the operating room. With theoutbreak of Coronavirus, this has become more vital as surgeon mobility and access to criticalsurgical spaces in need of more help are severely limited, and specialists will not risk enteringspreading viral hot zones.Patient care isn't just a concern with the virus itself, but with the host of medical issues facingpatients that will no longer be treated by local specialists easily, and facing caregivers: surgeoninvolvement from around the world is needed urgently.Although epiqar is an American company, our rollout in recent months has been inFrance, making selected French institutions the most prepared in the world for remote videocare. We obviously weren't anticipating the Coronavirus and now we're dedicated to deliveringour technology to where the world needs it asap.epiqar 's parent company ENGAUGE (https://eng.us/) is a state-of-the-art online healthcarecompany for surgeon training and has served clients such as Johnson & Johnson , IntuitiveSurgical, and many other of the world largest & smallest medical device companies.ENGAUGE has helped surgeons all over the world have access to secure online training thathas improved their understanding of the innovations in robotics and many of the latest surgicaltechniques and medical devices for best patient care.I've linked a whitepaper below with details of the system's use. Please let me know if you wouldlike to speak further and/or need anything additional.Thanks,NIH-001939Dannywww .epigar. comepiqa r I whitepaperDaniel GoldbergCEOENGAUGEwww .eng.uswww .epiqar.comThe world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platformus 888.615.7874EUROPE 44 2031399059From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Wed, 12 Feb 2020 00:16:12 +0000Conrad, Patricia (NIH/NIAID) [ElSubject : FW: AMA news interview request: What to tell your patients about COVID-19Let us di scuss.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Sara Berg <Sara.Berg@ama -assn.org>Sent: Tuesday, February 11, 2020 4:55 PM -------=-=-c= To: Fauci, Anthony (NIH/NIAID) [El (b)((;)>Subject: AMA news inte rview request: What to tell your patients about COVID-19Dear Dr. Fauci,My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because youhave shared a lot of great information about COVID-19 with the JAMA networ k. I know you are verybusy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rviewabout what to tell patients who suspect they have COVID-19? This would be an AMA news art icle forphysicians about what to tell patients. The CDC has a list of preventive steps :https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html .This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be"Call before you come in." Do you think this is something you would be available to participate in?I look forward to hearing from you.Thank you ,NIH-001940NIH-001941AMA~Sara BergSenior Communications SpecialistSara.Berg@ama-assn.orgOffice: (312) 464-410400000AMA membership: Join or renew today!MEMBERSHIPMOVESMEDICINE ...From:Sent:To:Subject:Attachments :Fauci, Anthony (NIH/NIAIO) [E)Wed, 12 Feb 2020 00:13:52 +0000Cassetti, Cristi na (NIH/NIAID) [E]FW: 2019 nCoV brief fyi (2+ pages)Brief 2019 nCoV host Se status.docPlease handle. Thanks.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBui lding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Michalann Harthill (b)(6)Sent: Tuesday, February 11, 2020 3:41 PM -------=-:--:= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) :.::========-=.,~ Cc: Morens, David (NIH/NIAID) [E] ---------- (b)(6) Subject : 2019 nCoV brief fyi {2+ pages)Dear Dr. Fauci,Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, HubeiProvince, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4pages, ~ 70 refs, no graphics)Best regards,Michal HarthillGHI, Inc., Frederick, MD(b)(6)NIH-001942From:Sent :To:Subject:Attachment s:Fauci, Anthony (NIH/NIAIO) [E)Wed, 12 Feb 2020 00:05:00 +0000(b)(6)FW: take a look at figure 3 of the new nejm papernejmoa2001316.pdfSee Greg/ David comment below .Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail. (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sen sitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Folkers, Greg (NIH/NIA ID) [E) --------- (b) (6)> Sent : Tuesday, February 11, 2020 2:50 PMTo: NIAID OD AM <NIAIDODAM@niaid.nih .gov>Subject: take a look at figure 3 of the new nejm paperThanks davidNIH-001943(b) (5)From: Folkers, Greg {NIH/N IAID) [E)Sent : Tuesday, February 11, 2020 10:04 AMTo: NIAID OD AM <NIAIDODAM @niaid.nih .gov>Subject: this is t he nejm paper discussed this a.m.That asf is opining on(b) (5lDisclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sionsof U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sentmy views nor those of NIAJD, NIH, HHS, or the U.S. gove rnment.NIH-001944From:Sent :To:Fauci, Anthony (NIH/NIAID) [ElTue, 11 Feb 2020 23:58:00 +0000NIAIDODAMSubject: FW: Keynote Invitation: 3/20 CSIS Coronavirus Public EventThis could be good since it is local. Let us discuss.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Stephen Morrison <SMorriso@csis.org>Sent : Tuesday, February 11, 2020 1:20 PM To: Fauci, Anthony (NIH/NIAID) [El --------------=---,,-(-b)(:6)- = Cc: Anna Carroll <ACarroll@csis.org>; Samantha Stroman <SStroman@csis.org>; Conrad, Patricia(NIH/NIAID) [El (b)(6)Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public EventDear Dr. Fauci,I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at aCSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island AvenueNW) . The event will focus on the science, economics, and politics of the coronavirus and will featureexperts on Chinese and international politics and economics, as well as public health . We would ask youto speak approximately 1:30-Z:OO pm. Your keynote would be followed by a panel discussion and aclosing address, and we invite you to stay for as much of the event as you are able . Please find the fulldraft agenda and speakers for the event below for your reference .We would be honored to have you participate in this important and timely event. Thank you for yourconside rat ion, and please let us know if you would like to discuss further or if we can answer anyquestions. We look forward to hearing from you .Best,SteveNIH-001945NIH-001946Draft Agenda:1:30-2 :00 pm - Opening KeynoteDr. Anthony Fauci, NIAIDIntroduced by Steve Morrison, CSIS Global Health Policy Center2:00-2:50 pm - Panel Discussion{The economics/business] Joyce Chang, JP Morgan (confirmed){The politics] Jude Blanchette, CSIS Freeman Chair in China Studies (confirmed)[The foreign politics] Melanie Hart, Center for American Progress (to be invited), or BonnieGlaser, CSIS China Power Project{The public health] Steve Morrison, CSIS Global Health Policy Center (confirmed)Moderato r : Scott Kennedy, CSIS Trustee Chair in Chinese Business and Economics2:50-3 :30 pm - Newsmaker SpeechMatt Pottinger, NSC (to be invited)Moderato r and Follow-up Interview: Bonnie Glaser, CSIS China Power ProjectJ. Stephen MorrisonSenior Vice President & Director, Global Health Policy CenterCenter for Strategic and International Studies (CSIS)1616 Rhode Island Ave NWWashington D.C. 20036(202) 775-3276From:Sent :To:Fauci, Anthony (NIH/ NIAIO) [ElTue, 11 Feb 2020 23:45: 51 +0000Lerner, Andrea (NIH/NI AID) [ElSubject: FW: Pharmacist's/ Prescriber 's Letter Review Request - Coron av irusPlease t ake a look at this and respond for me.Tha nks,TonyAnthony S. Fauci , MDDirecto rNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)( 6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave rece ived this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Jennife r Nieman <jnieman@pl et ter .com>Sent : Tuesday, Februa ry 11, 2020 11:00 AM ------- =---c-c= To: Fauci, Anth ony (NIH/ NIAID) [E] --------- (b)( 6) Subject: Pharmacist's/ Prescriber's Lette r Review Request - CoronavirusDear Dr. Fauci,In the March 2020 issues of Pharmacist 's Letter and Pre scriber's Letter, we plan to write aboutcoronavirus.Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians.We are not affiliated with any other group , organization, or company. We are 100% subscribersupported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drugtherapy . Each month we turn to experts like you to help us pin down the most relevant and importantinformation to share with our readers. Our newsletter is well known for being concise and accurate. Youwill notice the excerpt we are sending you is relatively short .NIH-001947NIH-001948We would be most appreciative if you would take just a few moments to review what we have written foraccuracy and content. Please share any comments or suggestions for changes you may have on thearticle.In order to incorporate your comments into the final Letter, please let me hear from you by Monday, Feb.17th. I can be reached by email jnieman@PLetter.com or phone (402) 660-4715.I look forward to your reply.INFECTION CONTROLThe ongoing ou tb reak of t he novel coronavirus wi ll raisequest i ons about how t o li mi t t he spread of r e sp i ratoryinfec t ion s .Managing this situation is similar to outbreaks of SARS andMERS ... s in ce coro nav i ruses are spread by resp i ratory secret i ons .Pu t t he risk in perspect i ve t o calm worr ie dpatients . .. since it doesn ' t come close to the risk of influenza .For example, over 35 MILLION U. S . patients got the flu lastseaso n . . . wi t h about 500 ,000 ho sp i ta li za t i ons a nd 34 ,000 deaths .Emphasize getting a flu vaccine each year .And us e this coronavirus outbrea k as an opportunity tostress infection control ... since there ' s no treatment o r vaccineyet .Reinforce p roper han d h yg iene . Educate t ha t ha ndwas hingwi t h soap a nd water i s t he best way t o g e t r i d of germs . Advisewas hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABCso ng .Or recommend using a han d sani t izer wi t h a t leas t 60%alcohol if handwashing isn ' t practical . Many prod u cts containthis much .But tell patients to be wary of efficacy claims . Fore xamp l e, ha nd sa ni t i zers are s ho wn t o kill en v e l oped v i ruses .Coronavir u ses are enveloped viruses ... b ut they aren ' tspecifically st u died .NIH-001949Tell patients to avoid touching their eyes, nose , andmouth .Clear up confusion about mas ks. Emphasize that mas ks arefor SICK patients ... to help keep their germs from gettin g intot he a ir .But d i scourage surgica l masks for mos t patients withOU Tsymp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t ol imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th ee yes .I f pat ien ts ask about N95 res p ira t ors , t e ll t hem t hesereq u ire fittin g and training before us e . Save them forhealthcare workers .Caution that unnecessary mask use may contribute toshortages .Continue to ask patients WITH respiratory symptoms to put as ur g ic a l mask on when t he y co me to c l inic .And suggest that sick patients wear a mask at home if inclose contact with infants , elderly , or immunocompromisedpatients .Te ll pat ien t s t o discard masks when da mp ... and t o use afresh one at least daily .Encourage pat ien ts t o s tay home when t hey ' re sick.1. https://www.who.int/emergencies/diseases/novel-coronavirus-20192. https://www.cdc.gov/coronavirus/2019-ncov/index.html3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm4. https://www.who. int/publications-detail/advice-on- the-use-of-masks-the-community-durinq-home-care-and-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(2019-ncov)-outbreakSincerely,Jennifer A. Nieman, PharmD, BCPSAssocia te Editor, TRC HealthcareM: 402-660 -4715 E: jnieman@pletter.com W: TRCHealthcare .comPham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians UniversityFrom:Sent:To:Cc:Subject :Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 23:06:37 +0000Billet, Courtney (NIH/NIAID) [E]Conrad, Patricia (NIH/NIAID) [E]FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily]Can we please get someone to fashion answers for me to edit and send to her.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail Cb()6 )The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: ~fm/§ <ymhan@stimes.cn>Sent: Monday, February 10, 2020 2:54 AM ------ ..-.-,= To: Fauci, Anthony (NIH/NIAID) [E] (bH >Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily]Dear Prof. Anthony,I am yangmei Han, a journal ist from CHINAS CIENCED AILY.Chi na Sc i ence Da i I ya newspaper in Chinese, pub I i shed by The Chinese Academy of Sciences.ISRecently, your article " Coronaviru s Infectio ns- More Than Just the Common Cold "mention about vaccinesinterested and there areget more informations.research 1n NIAID. We aresome questions and I want to1, What is the current research progress about vaccines 1n NIAID?NIH-0019502-.. What are the factors restricting the development of vaccines? and did you breakthrough them?3 .. What is the standard of vaccine that can be injected to patients? and accordingyour forecasting, how will it work?4 .. Can this vaccines research play a role in the 2019-nCoV? Or as a treatment for acommon infectious disease in the future?5, Does vaccines have side effects? how can we restrain it?6, If vaccines research success in a certain country, Will it be open to theworld? if it will , what conditions will need for open?if you could, we would I ike you rep ly as soon as possibleThank you very muchI am looking forwa r d to your reply!Si nee re I y yours ,Yangmei Han (Miss)~tw~q:oi of:.I:.1~t& t * tnc :,:1)p t c~BlB~:B y mhan@stimes .cn;576942717@qq .eomit i! : (b)(6)i'!EiJt:~ t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~NI~H:±J:q:iOOf~:.t1t:.~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M ~ ~ * ~~~~· §&~~~m-~~~~~$·~-~~~~-%~M~••·NIH-001951From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 20:54:02 +0000Natalie RahhalRE: Interview re: coronavirus patient characteristicsIf th is is true, which it might not be, there is no clear explanation for why rightnow . There will likely be studies coming out that say that the relative proportionof male:female is closer to 50:50. Even one of the ones that you quoted was54%Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone Cb()6 )FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Natalie Rahhal <Natalie .Rahhal@mai lonline .com>Sent: Tuesday, February 11, 2020 1:55 PM ------- ~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: Interview re: coronavirus patient characteristicsHi Dr Fauci,I'm sure you're extraordinarily busy right now, but I've seen several stud ies and reports that coronavirusseems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study youreference). I was wondering if you might have any comments to offer on why this mig ht be?Thank you,Natalie A RahhalActing US Hea.lth EditorDailylll4'lil.comNIH-001952Daily Mail Online I 51 Astor Place, 9th floor, New York NY 10003Tel: +1212402 9086Mobile : (b) (6)Twitter : https ://twi t ter .com/nata lier78?1ang=enEmail: Natalie.rahhal@mailonline.comDisclaimerThis e-mail and any attached files are intended for the named addressee only. It contains information, which maybe confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( orauthorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received itin error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd.Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England.NIH-001953From:Sent:To:Subject :Gary:Thanks for the note.Best,TonyAnthony S. Fauci. MDDirectorFauci, Anthony (NIH/N IAID) [E)Tue, 11 Feb 2020 20:10:45 +0000Nabel, Gary / USRE: WHO meeti ngNational Institute of Allergy and Infectious DiseasesBuilding 3 I, Room 7 A-033 I Center Drive, MSC 2520National Jnstitutes of HealthBethesda, MD 20892 -2520Phone: (b) (6)FAX: (301) 496-4409E-mail: (b)(6)(b) (4)The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . Itshould not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in errorplease inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute ofAllergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's ownand not express ly made on behalf of the NIA ID by one of its representatives.-----Original Message--------------=-=-= from : Nabel, Gary /US (b) ((b)(Sent: Tuesday, February l l , 2020 1:19 PMTo: Fauci, Anthony (N1H/N1AJD)[ E)- -------- Subject: RE: WHO meetingNot a problem. I j ust wanted you to know that I was willing to help.BestGary-----Original Message-----From: Fauci, Anthony (NlH/NlAID) [E] --------- (b)( Sent: Monday, February 10, 2020 3:07 PMTo: Nabel , Gary /US (b)( 6)>NIH-001954(b) (4)Subject: [EXTERNAL] RE: WHO meetingEXTERNAL: Real sender is (b)(6) _______ _,T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: (301) 496-2263FAX: (301) 496-4409E-mail: afauci@niaid.nih.govThe infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. ltshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox. or any other storage devices. The National Instinite ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's ownand not express ly made on behalf of the NIA.lD by one of its representatives.-----O riginal Message- ---- ---------=--=-= From: Nabel, Gary /US (b) (Sent: Monday, February I 0, 2020 2: 17- -P-M- ---~~ To: Fauci. Anthony (NTH/NIAlD)[ E]_ _____ C)bC_,Subject: WHO meetingHi TonyThanks for taking the time to talk and help with the HTV trispecific work last week. I appreciate your efforts.While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend buthave not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunateand to their detriment. In any case, please let me know ifl can help in any way.Best regardsGarySent from my iPhoneNIH-001955From:Sent:To:(b)(6)Tue, 11 Feb 2020 11:22:43 -0500Mart in BlaserCc:(NIH/NIAID) [E]Subject:Conrad, Patricia (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIAID) [E];Lane, CliffRe: SARS 2003, Influenza 2009 and the presentMarty:Than.ks for the note. Indeed, immune sera is foremost on our mind as are mAbs. Hope that allis well with you.Best,TonyOn Feb 11, 2020 , at 9:55 AM, Martin Blase rCb)( wrote: ------------Dear Tony,I dont mean to bother you, but I have a suggestion, in case you have notconsidered it.China will have hundreds of thousands of Coronavirus surv ivors . Their convalescent(immune) serum is valuable. China should try to collect it and give it as a good-willgesture to people around the world.For moderately to seriously ill people, Immune serum should save many lives.If cases start to come here, we also should collect serum from survivors, buthopefully we will be very late in the pandemic, and it is not needed because of allof the others th ings you are doing.Thank you for everything you and NIAID are doing!Best wishes, Marty(Just as in SARS, the Ro for nCo-2019 is higher in hospitals than in the community,but it still is too high in the community).Martin J. Blaser, M.D.Henry Rutgers Chair of the Human MicrobiomeProfessor of Medicine and Microbiology-RWJMSDirector, Center for Advanced Biotechnology and MedicineRutgers University679 Hoes Lane West, Room 106APiscataway, NJ 08854Office Phone: (b)(6) Fax: 7 2-235--fi3._- 1_8 - __-___-_ - ~=Emili oo~NIH-001956httPs ://cab m.rutgers.eduFrom: Fauci, Anthony (NIH/NIAID) [El (b)(6) ________ ......Sent: Sunday, January 26, 2020 7:16 PMTo: Martin Blaser (b)(6):Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6)Subject: RE: SARS 2003, Influenza 2009 and the presentMarty:Many thanks. Th is is very helpful.Best regards,TonyFrom: Martin Blaser (b) (6)Sent: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6)Subject: SARS 2003, Influenza 2009 and the presentWebb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm issionin the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1:1-13. [PMID: 203699561 [Paper of the year, 2004]Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre-symptomatic influenzatransmission, surveillance, and school closings: implicat ions for novelinfluenza A (HlNl). Mathematical Modelling of Natural Phenomena2010 ; 5:191-205.Dear Tony,Thanks for your JAMA piece on 2019-nCoV. Perhaps I can help in asmall way:In 2003, with SARS, the Ro was initially considered to be over 2, but infact that was the conflation of the nosocomial and community rates. In the2004 paper , we showed that nosocomial rate was much higher, and that theRo in the commun ity was between 1 and 2. A lower Ro in the communityaccounts for why modera te public health actions could move it towardextinction--and why it propagated in Beijing, but not Shanghai , in TorontoNIH-001957NIH-001958but not in Vancouver--the Ro in North America became less thanone pretty quickly.To me, one important aspect is the control of respiratory tran smission inthe hospital, avoiding extensive nebulization /aerosolization, or doing so innegative pressure rooms , as for TB isolation.(Treating patient s with robots is a good idea!)In the communit y, standard public health quarantine, contact tracing shouldbe sufficient for staiie rs.Although hundreds of cases are reported in China, the actual number ofinfections is likely much higher. The 41 deaths are the tip of the iceberg ofnot 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%).Although that rate is much better, if the mutating virus becomes verycontagious- then the impact could be similar to 1918 flu. That's whycontainment is so important-and although draconia n, the Chinesegovernment is doing the right thing (as far as we know).When a new pathogen arrives, children often have mild disease but theyare important vectors for transmi ssion in the cotrununity , reaching manyhouseholds. The second paper is the imp01iance of closing schools to minimi zetransmi ssion- This was for flu with a short (pre-symptomatic) incubation , but maybe even more relevant for 2019-nCo V. It is much too eai·ly to even think of this inthe USA, but it may come to this--and sooner will be better than later, when thattime point comes.Happy to help, any way that I can. Thank you for all you and NIAID aredoing!!!Best wishes , MartyMartin J. Blaser, M.D.Henry Rutgers Chair of the Human MicrobiomeProfe ssor of Medicine and Microbi ology- RWJMSDirector, Center for Advanced Biotechnology and MedicineRutgers University679 Hoes Lane West , Room 106APiscatawa y, NJ 08854Office Phon e: (b)(6)Fax: 732-235-53·-1--8- ---~ = Emai l ---------------- (b) (6) http s: I I cabm.rutgers. eduNIH-001959From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 13:22:53 +0000Conrad, Patricia (NIH/NIAID) [E)Subject : FW: Interview/ Coronavirus vaccine - Pazienti.itHave Jen Routh or someone prepare bri ef responses that I can check. Thank s.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Alessandra Lucivero <alessandra.lucivero@pazienti.it>Sent: Tuesday, February 11, 2020 5:35 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( >Cc: Camilla Mantegazza <camilla.mantegazza@pazienti.it>; Irene Bacca <irene.bocca@pazienti.it>Subject : Interview/ Coronavirus vaccine - Pazienti.itGood morning prof. Fauci,my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an Italian health website,followed by over 3 million users every month .We would like to ask you some questions related to the Coronavirus vaccine.We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute.The questions are:• Coronavirus vaccine: when will it be available? What are the difficulties?• Could the Corona virus mutate, if a vaccine cannot be found in time?• Will the vaccine be the solution against Coronavirus?I hope you can be kind enough to answer my questions .I look forward to hearing from you.Thank you very much for you r time.Alessandra LuciveroNIH-001960Alessandra LuciveroResponsabile editorialea lessandra. I ucivero@ pazienti.itPa z Ie nT 1.itII portale della salute dove farsi vedere da uno bravo.Pa:u enTLQuesto messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, lamodifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questodocumento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Viinjormiamo inoltre che questo indirizzo di posta e utilizzato solo a scopo professionale: non si garantisceche la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinatecircostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consigliadi non inviare messaggi di natura personale. Grazie.NIH-001961From:Sent :To:Subject:Attachment s:Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 13:14:45 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: Coronavirus Auto Terminat ionRetrovirus Auto Termination.PDFPlease handle . Thanks.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sen sitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e -mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Pali Nazir (b)(6)>Se nt: Tuesday, February 11, 2020 4:32 AM ---------=-:-= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Chun, Tae-Wook (NIH/NIAID) [E](b)( ; Connors, Mark {NIH/NIA ID) [E] (b)( ; Lane, Cliff'7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__~--=(NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) [El (b)(6J>; Sereti, lrini(NIH/NIAID) [El =====~ (b::);:~(6)Subject: Coronavirus Auto TerminationDear Mrs . / Sir,We have a solution to the new recent global problem Coronavirus (2019-nCoV).Best Regards,Dr. Pali NazirNIH-001962From:Sent:To:Subject :Please handle. Thanks.Anthony S. Fauci, MDDirectorFauci, Anthony (NIH/NIAID) [E)Tue, 11 Feb 202013:12:28 +0000Cassetti, Cristina (NIH/NIAID) [E)FW: coronavirusesNational Institu te of Allergy and Infectious DiseasesBuilding 31, Room 7 A-0331 Center Driv e, MSC 2520National Institu tes of HealthBethe sda , MD 20892 -2520Phone: (b) (6)FAX: (301) 496-4409E-mail: (b)(6)The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. Itshould not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITorplease inform the sender and delete it from your mailbox or any other storage devices. The National Institute ofAllergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's ownand not expressly made on behalf of the NlAID by one of its representatives.-----Original Message-----From : (b)( ·Sent: Tuesday, February 11, 2020 8:0 I AMTo (b)(6)Holbrook , Michael(NIH/NlAID) [CJ .__ ______ C_Hb....>, ; Fauc i, Anthony (NIH/NlA1D)[ E].__ _____ CHb _,,Subject: coronavirusesHello,Working as an occupational physi cian iu F1ance, I would like to draw your attention to the antiviral activity ofproton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not require acidificationof eod osomes for entry into ce lls, as is the case with corona viruses.Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Omeprazole andEsomep razole were also able to inhibit entry of all PV s tested but at high er drug concentrations than may beachiev ed in vivo ... >>.Using omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma), they conc luded that«... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH, only at a concentrationof200μM, higher than that required to inhibit PV entry . Moreover cellular toxicity was observed at thisconcentration after 24 hours ... ».In 2016, Dowall et al. (2) found : « ... Whereas omeprazole and esomeprazole demonstrated in vitro activity againstEBOV, the results were in line with a previou s report using pseudotyped viruses where the values of drugconcentration caus ing 50% inh ibition (IC50) were in the region of 50 μM [10). This suggeste d that doses requi redfor potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosingfor 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasmaconcentrations of 1.59- 9.61 ~tM, 0.51-4.78 μMand 0.15-3.51 μM, respectively .. . >>.However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to beNIH-001963NIH-001964transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group ofthe cysteine of the a subunit of the proton pump.The solution used in 2015 by Jason Long et al. was, as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide).DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanationfor the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 μM (at50 μM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M.This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ationomeprazole can be ionized in the intracellular space but also already in the extrace llular space.Besides, that's probably its advantage: to be ionized and activated where there is an acidic environmen t.Without taking into account the tissue situation and the need that omeprazole must be ionized to be transformed intoan active molecule, it would not be possible to explain the following publications , since it would be impossible toobtain tissue concentrations required:(5)(6)(10)<< Proton pump inhibitors as anti vacuolar-A TPases drugs: a novel anticancer strategy>> (4)<< Anti-Rhinovirus activity of lansoprazole, whkh was probably due to an endosomal anti-acidic mechanism »« The use of omeprazole family compounds was associated with a lower probability of influenza-like illness»« PPls exert an antiviral function by effectively inhibiting virus-specific serine proteases>> (7)« Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8)« The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-A TPase » (9)« Omeprazole blocked another P-type ATPase, A TP7 A (Men kes protein) in human epidermal melanocytes »« pH-dependent anti tumor activity of proton pump inhibitors» ( 11)« V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role foromeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12)« Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acidity in gastritis, areactivated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibitionof V-ATPases in a covalent interaction» ( 13)« proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14)Specifically at the pulmonary level, we observe concerning proton pump inhibitors:« ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), weinvestigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability torestore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJesomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but thisresponse was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo lealka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istentwith a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASLpH in CF airways, which is independent ofCFTR .... » (15)NIH-001965« ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells,exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show thatesomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependentmanner but, chronic exposure, which importantly did not have any deleterious effect on epithelialintegrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTsas a new therapeutic approach for treating CF lung disease ... » ( 15)« ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with thegastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15)« Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16)« Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia »(17)« ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential modelto study proton pump inhibitor-associated pneumonia>> (18)Regarding coronaviruses and Golgi complex:« ... Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediatecompartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) aresynthesized in the ER and move to the ERGIC/Golgi region where they orchestrate assembly of virus by interactingwith the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particlesmust move through the host secretory pathway to be released from infected cells. Coronaviruses are believed tofollow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release ofvirions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemaelate in infection ... >>« . .. Weak bases (which disrupt acidification), v-ATPase inhibitors , and expression of a pH activated proton channelall block a number of membrane trafficking steps( . .. ) One mechanism for how luminal pH can affect vesicu lartrafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensorin endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmicmachinery leading to subsequent vesicle fonnation ... » (19)« ... Phannacological and other manipulations of the pH gradient that result in neutralization of the lumenhave all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgimorphology ... »« ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathwaydisruption phenotypes when overexpressed in mammalian cells ... » (20)« ... The envelope protein (E) of coronaviruses plays an important role in virus assembly ( ... ) Usingcoronavirus infectious clones, it was shown that the transmissible gastroenteritis virus E protein is essential for vimsproduction , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >>« ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediatecompartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably enroute to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22)« ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pumpinhibitors specifically are able to inhibit this increase in Golgi pH . For now, though , it still remains to be seenwhether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of thesecretory pathway ... » (23)« V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi tolysosomes » (24)NIH-001966« ... cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +ATPase, inhibited infection of ceUs with MHV, FIPV, Middle East respiratory syndrome (MERS)-CoV, and VSV,but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibitentry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence,in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassedby low-pH shock. Viral RNA replication was not affected when these compounds were added after virus entry. Theantiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Srcsignaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ... » (25)In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection bycoronaviruses :Tbe equivalent oftbe maximum serum concentration that can be obtained in the human body should be usedand tested in active (ionized) form in vitro .Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbeionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of activetransport.But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of thereactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an activeform, linked to a change in acidity or the depletion of the inactive form.As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellularlevel (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities ofomeprazole with protein E of the corona virus. Protein E is likely to resemb le the protein M2 in its mode of action.In the absence of a treatment recognized as effective in the context of a coronavirus infection and in theabsence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to takeomeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if lhad the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the contextof coronavirus exocytosis , in analogy to the action "off target on the endosomal v ATPase" during endocytosisprocesses.This step, if effective, will not prevent infection , but could lessen its importance, slow the process down and give tbeimmun e system a complementary option to defend itself...Personal experience, using omeprazole in the context of seasonal respiratory viral infections since 2007,reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening isusually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance ofinflammatory state I associate an antihistamine, eg cetirizine.In the context of the coronavirus , I would be temptedshare tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact withpeople at risk of contamination at a distance of less than 2 to 3 metersdivide tbe daily dose of omeprazole into two daily doses in case of minor symptomstake the daily dose of omeprazole in a single dose if the symptoms worsen with repercu ssions on the genera lconditionto resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish.The effectiveness of esomeprazole may be greater than omeprazole.NIH-001967Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reducesecretions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute viral respi ratory diseaseswhich can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) duringprolonged use, thus promoting the risk of bacterial pneumonia (29).The adva ntages and disadvantages may vary depending on the user phenotype of omeprazole with regard tocytochrome P 450 (30).Best regardsJohann es HamburaI. Long J, Wright E, Molesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emergingvira l diseases using existing medicines that block virus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29.doi: 10.12688/fl000research .6085 .22. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus.Viruses. 2016;8(11):277. Published 2016 Oct 27. doi: 10.3390/v81102773. Shin JM, Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. JNeurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.254. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncerstrategy. J Exp Clin Cance r Res.20 10;29( 1 ):44. Published 2010 May 8. doi: 10.1186/1756-9966 -29-445. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kubo H, Nish imura H, Sasak i H. The proton pumpinhibitor lansoprazole inhibits rhinoviru s infection in cultured human tracheal epit helial cells. Eur J Pharmacol.2005;14:201 - 210. doi: 10.1016/j .ejphar.2004 .12.042.6. Gaspari ni R, Lai PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect againstinfluenza- like illness? . BMC Infect Dis. 20 14; 14:297. Publ ished 2014 Jun 2. doi: 10.1186/1471 -2334-14 -2977. Moorn1ann AEBDP, Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors asantiviral agents . United States 1999 Jun. 14, 2005.8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N. Proton pump inhibitors for chronic obstructi ve pulmonary disease.Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 139. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M,Geering K. Nongastric H,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 .10. Matsui MS, Petris MJ, Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole ,a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015Mar; 135(3):834-841.l I . De Milito A, Canese R, Marino ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E, Logozzi M,Mina PD, Santi nam i M, Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proton pumpinhibit ors aga inst human melanoma is mediated by inhibition of tumor acid ity. Int J Cancer. 2009 .12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhance the effects of cytotoxic agents inchemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.531913. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of itsNIH-001968pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I 08:23-35.14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M,Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitorpretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713.15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway SurfaceLiquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11.doi: 10.3389/ fphar.2018.0146216. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC,Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjaepneumonia. Aliment Phannacol Ther. 2012 Nov;36(10):94l-9. doi: 10.1111/apt.12069. Epub 2012 Oct 3.17. Sun DI, Tasca A, Haas M, et al. Na+/H+ Exchangers Are Required for the Development and Function ofVertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/00049297318. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopusmucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol.2015;408(2):292-304. doi: I 0.1016/j.ydbio.2015.03.01319. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261-269. doi: 10.1007/s00418-013-1120-y20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein AltersGolgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019,93 (11) e00015- 19; DOI: 10.l 128/M .00015-1921. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required forefficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID:17037529 DOI: 10.1007/978-0-387-33012-9 3322. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretoryproteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I 05: 1215.23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019).https://doi.org/10.1186/s l2985-019-1182-024. Pamarthy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation ofsignaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I 0.1 I 86/s 12943-018-0811-325. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015.ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448.doi:10.l 128/JVI.03274-1426. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R.Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to InfluenzaVirus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.18827. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Cells: So1iing and Regulation of the Na+,K+andH+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 0002320028. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci.2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 908215429. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of ProtonNIH-001969Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-930. El Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precisionmedicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835From :Sent :To:Subj ect :Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 12:52:45 +0000Conrad, Patricia (NIH/NIAID) [ElRE: WTOP RequestOK by me. Please set it up.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Conrad, Patricia (NIH/NIAID) [ElSent : Tuesday, February 11, 2020 7-:3-7- A-M- ---, .....,....,= To: Fauci, Anthony (NIH/NIAID) [El- -------- (b)(6) Subject : Fwd: WTOP Request1040 before you depart for aspen event?Sent from my iPhoneBegin forwarded message:From: "Chesson, Joslyn" <jchesson@wtop .com>Date: February 11, 2020 at 7:16:26 AM EST(b)(6)>To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -(,b;;)~- (=6)>Subject : WTOP RequestGood morning,Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss thecoronavirus and the quarantining on cruise ships.We have 10:40a, 11:lOa, and 12:10pm all open .NIH-001973NIH-001974Let me know if any of those times work for him!Thanks,Joslyn ChessonEditorWTOP News(202) 895-5060From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Tue, 11 Feb 2020 12:20:02 +0000To: Lisa MonacoSubject : RE: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease aNational Security Priority - LawfareLisa:Thanks for the note and for sending this. Very ruce piece! I hope that all is well with you. I miss very muchour interactions.Best regards ,TonyAnthony S. Fauci , MDDirectorNat ional Institute of Allergy and Tnfectious DiseasesBui lding 31, Room 7A-0331 Center Drive, MSC 2520National In stitutes of HealthBethesda, MD 20892-2520Phone: (b) (6)FAX: (30 I) 496 -4409E-mail (b) (6)The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. Itshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox or any other storage de vices. The National Institute ofAllergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's ownand not express ly made on behal f of the NIAID by one of its representatives.-----Orig inal Message-----From: Lisa Monaco _______ ..(."b,~"..('.6=, )Sent: Monday,febrnary 10, 2020 8:09 PMTo: Lisa Monaco (b)(6)Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - LawfareIn case you missed this, my latest on the coronovirus.https:/lwww.lawfareb log.com/co ronavirus -shows-whv-us-must-make -pandemic-disease -national-security-prioritySent from my iPadNIH-001975From: Fauci, Anthony (NIH/NIAIO) [E)Sent: Mon , 10 Feb 2020 22:44:53 +0000To: Routh, Jennifer (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy(NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E]Subject: RE: for review: responses for Washington TimesAtt achment s: responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docxSee my tr acked changes in at tached document . Thanks.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It shou ld not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Routh, Jennifer (NIH/NIAID) [E]- -------- (b)(6) Sen t : Monday, February 10, 2020 4-:0-7 -P-M- - ::;..,..-,= To: Fauci, Anthony (NIH/NIAID) [E]~ ======(~bH~ > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E)(b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea(NIH/NIAID) [E_ ______ C_>b<6JF olkers, Gre"g" -(:N--I:H--/N"'"I"A"I'D.")' -[:E-:]-_ :_:-_=_=_:_::_: :.:...--,.;_-=-Cc_-Hbc_6-=)>-tSubject: for review: responses for Washington TimesDr. Fauci -The reporter Shen Wu Tan from the Washington Times reached out to us this morning with somequestions about 2019-nCoV. I drafted proposed responses to these questions with input from Andrea.Please see attached. Please let me know if you have edits . I will send the final responses back to thereporter, and I will note they are attributed to you .Thanks,JenJennifer Routh [E]News and Science Writ ing BranchOffice of Communications and Government RelationsNIH-001980National Institute of Allergy and Infectious Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda, MD 20892Direct: Cb()6 )CbHDisclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not beused by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete iifrom your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives.NIH-001981From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 10 Feb 2020 20:22:28 +0000Routh, Jennifer (NIH/NIAID) [E]Subject:coronavirus?FW: Wpost : Q&A with Anthony Fauci: Are we past the point of containment forLet us discuss.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBui lding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sen sitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e -mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Folkers, Greg (NIH/NIA ID) [E) -------- (b) (6)> Sent : Monday, February 10, 2020 2:37 PMSubject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus?OpinionsQ&A with Anthony Fauci: Are we past thepoint of containment for coronavirus?NIH-001982man wears a protective mask while walking inWuhan, China, on Feb. 10. (Stringer/AFP/Getty Images)ByRobert GebelhoffAssistant editor and Opinions contribu torFeb. 10, 2020 at 2:22 p.m. ESTThe latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsingthe body count from Chino's SARS outbreak in 2002 and 2003 .To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5.Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at theNational Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity andbrevity .Robert Gebelhoff: Right off the bat, what makes this virus different?Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to usea big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no realunderlying experience with it, so the general population is naive with regard to protection . And it hasserious potential, because it's already spreading rapidly . It's the unknown aspect of something thatalready tells you it's a serious problem. We don' t know where it's going.Gebelhoff : Are we past the point of containment for this coronavirus?Fauci: No, we're not. The short answer is we're not past the point of containment. But it really doeshave the potential to turn into a global pandemic . What we have now is a very serious epidemic inChina .. .. [But outside of China,] there is very little - but some - transmission from person to person .Once you get mult iple countries that have sustained transmission from person to person, then it 'sbeyond the situation where you can contain it. You can only mitigate it.In the United States, we are clearly in the containment phase .... And what we've done is we'veidentified . We've isolated . And we've done contact-tracing [identifying who might have come in contactwith an infected person]. That seems to be successful. But once it it starts spreading all over the world ...then it's almost inevitable that it's going to start spreading here .Gebelhoff : The Post reported last week that China withheld information from the public, includingsilencing medical professionals, and that this made the spread of the virus worse. How does the UnitedStates work with a governm ent that we can't even trust to tell the tru th to its people?NIH-001983Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people -CDC, NIH people - there on the ground , both helping and seeing with their own eyes exactly the extentof this. We want to be part of a [World Health Organization] convening group that goes there. But thusfar, we've not been able to make that a reality.Gebelhoff: And why's that?Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we'vedealt with for years if not decades. Many of them have trained in the United States. And we know themas friends and as colleagues. They are the ones that are not holding back .... But they're not the onesthat make the official proclamations of what comes out. The solution to the problem in the questionyou're posing is that we really do want people there, so that we can not only help them but also providesome expertise that might supplement or complement their own expertise.Gebelhoff: What does the United States do if [the coronavirus] does become a pandemic in thedeveloping world?Fauci: Well obviously we will try to help them to contain as best as possible .... Right now, by definition,it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount ofsustained transmission outside of China is still minimal. ... But there are some countries where it is goingto be very difficult to stop the evolution into sustained transmission. Obviously the [World HealthOrganization] and the global security network that we put up over the years will try to help thosecountries, but there's no guarantee that we'll be successful.Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around theworld as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma."WhatFauci: Everyone agrees that travel bans and restrictions are almost never successful In completelystopping something is that invariably going to turn into a pandemic .... What we are trying to do is topause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becomingglobal and to give us a little more time to prepare. There's no indication or imagination that if thisbecomes a global pandemic that travel restrictions are going to mean anything . But they can meansomething , as a temporizing activity.Gebelhoff : What should the average person be doing right now about coronavirus?Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk canchange, so pay attention to what's going on [and] to the ... announcements coming from the CDC. ... Thethings that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactlythe same things that you would do if we did get coronavirus here. So the question is, should we doanything different from what we're already doing? No. Should we all be wearing a mask? Absolutelynot.Read more:The Post's View: The virus that shook China's systemChen Guangcheng: Warning: Chinese authorit arianism is hazardous to your healthDavid Ignatius: The coron avirus out break shows the vulnerability of t he 'Chinese model'John M. Barry: Can th is virus be contained? Probably not.John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peopleRobert GebelhoffNIH-001984NIH-001985Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since2015 .FollowDisclaimer : Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily representmy views nor those ofNTATD, NTH, HHS , or the U.S. governme nt.From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 10 Feb 2020 20:18:24 +0000Billet, Courtney (NIH/NIAID) [E]Subject: FW: Potentia l Treament Strategy to Reduce Motality Caused by CoronavirusInfectionNIAID inquiries, PleaseAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: (b)(6) ----------------- Se nt: Monday, February 10, 2020 3:02 PM ------~~ = To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: Potential Treament Strategy to Reduce Motality Caused by Coronavi rus Infectio nDear Dr. Fauci:One effect ive way to get th ings done is through the individuals like you at the frontline with authorities .I know that you are very busy, and I am sorry to bother you. You probably already knew what I'm goingto say and appear to be so relaxed.With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbasedimmunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal causefor t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icleentitled " Extending the Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms ofAction of Photopheresis" and ot her related arti cles on this topic .Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinicaldata support this motion , which include : (1) ozone therapy ( withdraw about SO ml -100 ml bloodfrom patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ientin 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuumseffec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order toreinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at theNIH-001986NIH-001987period of fever, viremia stage. These simple approaches can be incorporated with the other medicaltreatments and support ive care.I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this emailand providing your insight as well as help.Sincerely,Ching Y. Voss, M.D.From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon, 10 Feb 2020 20:10:11 +0000Conrad, Patricia (NIH/NIAID) [ElSubject: RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DCSorry. Cannot do. Congressional Hearin g.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Zev Moses <zev.moses@usasiainstitute .org>Sent : Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E)- ------~~ CbH6)>F; auci, Anthony (NIH/N IAID) [E)-------- CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DCGood afternoon,The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event onFebruary 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation isattached.This event will focus on the public health impacts of the novel coronavirus, the facts on the ground,trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staffon these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci'scurrent research is vital to support ing productive and informative dialogue.Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in thisevent. We would be honored to host him or others from NIAID and our audience would be extremelyinterested to learn from your agency's research.Sincerely,Zev MosesNIH-001988NIH-001989Zev Moses I Director , International & Government AffairsUS-Asia Institute232 East Capitol St. NEWashington , D.C. 20003202-544-3181www.usasiainstitute.orgFrom:Sent:To:Subject:Washington, D.C.Atta chments:Fauci, Anthony (NIH/NIAIO) [E)Mon, 10 Feb 2020 19:19:42 +0000Conrad, Patricia (NIH/NIAID) [E)FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting inDr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdfLet us di scuss. We do not need to bring befo re th e OD AM grou p. I wo uld like todo t his if possible. It is an invitat ion f rom Meghan O'Sullivan who was one of thesecur ity crew fr om Bush 43.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Richard Fontaine <rfontaine@trilateral.org>Sent: Monday, February 10, 2020 11:30 AMTo: Fauci, Anthony (NIH/NIAID) [E)_ _____ (=b)'"("=6' )>Cc: Meghan O'Sullivan (b) (6) Torrey Taussig <ttaussig@tr ilateral.org>Subject: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Washington, D.C.Dear Dr. Fauci,The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., onMarch 13-15, 2020. I would like to invite you to participate in a conversation at the meeting onresponding to the coronavirus and global pandemics .As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think throughthe shared challenges and leadership responsibi lities of the three principal industrialized democraticareas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes itsoriginal mission of bring ing democrat ic countries together to tackle international challenges should onceagain be a majo r priority for our country and our partners . This year's plenary meeting is a major, three daygathering of our global membership during which we will explore the theme "Democracy andCapitalism at a Crossroads."NIH-001990NIH-001991Your participation would make a great difference if you are available. Attached to this email you will findan invitation from North American chair Meghan O'Sullivan. Please do let us know if you have anyquestions about the event or your potential role in it, and we hope that you are able to accept ourinvitation .Best wishes,RichardRichard FontaineExecutive DirectorTrilatera l Commission - North AmericaFrom:Sent:To:Cc:Subject :Eric:Fauci, Anthony (NIH/NIAIO) [E)Mon , 10 Feb 2020 18:52:31 +0000Strauss, Eric M.Conrad, Patricia (NIH/NIAID) [ElRE: Heat kills novel CoronavirusThe following is all on background. Coronaviruses in general tend to circulateand infe ct predominantly in the winter season {Northern and Southernhemispheres have opposite seasons). We do not know for sure why th is is thecase; however , many believe that the enclosed spaces in winter {mostly indoorbecause it is cold) allows better spread of a respiratory borne virus. Also, someviruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather.Remember, however, that when it is summer here , it is winter in Australia andArgentina . This may be the genesis of the information given to President Xi andPresident Trump that the virus may "go away" in the warm weather. However ,this is a brand new virus with which we have no pr ior experience and it is entirelyconceivable that seasonal changes will not have any impact on the spread.Hope t hat this is helpful.Best,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520Nationa l Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301 496-4409E-mail : (b)(6]The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended rec ipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Strauss, Eric M.<Eric.M.S tr auss@abc.com>Sent: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>Subject: Heat ki lls novel CoronavirusNIH-001992NIH-001993Dr. Fauci:We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medicallysound?Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and theChinese president told him "the heat generally kills this kind of virus."The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talkingabout having to do a lot of people. We think that goes away in April with the heat," he said.Eric M. Strauss, ABC NewsManaging Editor, Medical Unitwww.ericmstrauss .comPhone: 212-456 -2016Connect on Social: T/1/F = @ericMstraussFrom:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 10 Feb 2020 18:08:29 +0000Jon LaPookSubject:Attachment s:FW: "Coronavirus is airbo rne, Chinese official confi rms"Amoy Gardens and SARS.pdfJon:Thanks for the note. See attaclunent for our future discussion.Best,TonyAnthony S. Fauci , MDDirectorNat ional Institute of Allergy and lnfoctious DiseasesBuild ing 31, Room 7A-0331 Center Drive , MSC 2520Nat ional In stitutes of Hca llhBethesda , MD 20892-2520Phone: (b)(6)FAX: (30 I) 496-4409E-mail: (b)(6)The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . Itshould not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox or any other storage de vices. The National Institute ofAllergy and Infectious Diseases (NlA lD) sha ll not accept liability for any statements made that are the send er's ownand not express ly made on behalf of the NIAID by one of its represe ntatives.-----Orig inal Message-----From : Jon LaPook ,.::;....---~ (~b)~(=6)>Sent: Monday , febrnary 10, 2020 10:0-8- A--M- -~-= To : Fauci, Anthony (NlH/NIAID) [E) (b)(6) >Cc: amb@cbsnews.com ; Kev in Finnegan <kpf@cbsnews.com >; Alturo Rhymes <RhymesA @cbsnews.com >; JayShaylor <Shaylor@cbsnews.com >; CBS LaPook <lapoo]tj@cbsnews.com >Subject: "Coro naviru s is airborne, Chinese official confirm s"Hi To ny,I need a Fauci brain dump.You may have seen this:https :/fwww .nzherald .co . nz/wor ld/news/ articl e.cfm?c id=2&objecti d= 12307276Is this news? Don' t we already know that the virus spread via droplet transmission? This article says aerosoltransmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha tmakes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infectsome body 2 hours after some body with measles leaves the room.Tomorrow, I wi ll be giving an hour and a half of affiliate debriefings on this virus. So we wi ll be reaching mill ionsof people. I'd love to get the latest and greatest public health message . Incidentally, Howard Zucker and theinfect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ientswho have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they havecoronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms toget wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowherein the n ear future , right?NIH-001998NIH-001999Thanks,JonJonathan LaPook, M.D.Chief Medical Corresponde nt, CBS NewsProfessor of MedicineNYU Langone HealthTwitter @DrLaPookFrom:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 10 Feb 2020 12:54:14 +0000Sciutto, JimSubject: RE: Long time, no see!Jim:Thanks for the note . All is well here except that I am not getting much sleep -coronavirus 24/7. I look forward to being on your show.Best regards ,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made t hat are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Sciutto, Jim <Jim.Sciutto@cnn .com>Sent: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------~-=- -- (b)( > Subject: Long time, no see!Glad to have you on the show today. Looking forward. Hope all is well. JimJim SciuttoNewsroom Anchor & Chief National Security CorrespondentCNNEmail: jim.sciut to@cnn.comMobile : ___ (b)( 6YTwitter: @jimsciuttoNIH-002002From:Sent :To:Cc:Fauci, Anthony (NIH/NIAID) [E)Mon, 10 Feb 2020 11:18:00 +0000Conrad, Patricia (NIH/NIAID) [E)Awwad, David (NIH/NIAID) [CJSubject: FW: REQUEST FOR A TV INTERVIEW ON WION TV INDIAWe did this before, but we cannot do it at 7:30 AM (b)(6) Ifthey want to do it later in the day and we can fit them in, then fine. If not, that is OK too. Notthe highest prior ityFrom: Latika Chugh {WION) <latika.chugh@zeemedia.esselgroup.com>Sent: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El------- (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ(b)(6)>; Oplinger, Anne {NIH/N IAID) [E] (b)(6); Richa Sharma --------- ( W 10 N) <Richa.sharma@zeemedia.esselgroup .com>Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIADear Anthony S. Fauci,M.D., NIAJD DirectorGreetings from WION!I would like to request for your time for an interv iew with us today for 10-15minutes at 7:30 am Monday, in Maryland , USA via Skype.It's regarding the upd ate in the story of Coronavirus -The World HealthOrganization chief says there have been 'c oncerning instances' of onwardtransmission of coronavirus among people who hadn't been to China.Waiting for your confirma tion.CLICK HERE TO WATCH WION LIVE :NIH-002003https://www.wionews.com/live-tvLive TV, News I wionews.com© 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved.www.wionews.comLook forward hearing from you .RegardsLatika ChughWION TV , IndiaFrom: Awwad, David (NIH/NIAID) [CJ- -------- (b) (6)> Sent : Thursday, February 6, 2020 6:41 PMTo: Latika Chugh {WION) <lat ika.chugh@zeemed ia.esselgroup.com>; KUMAR SUNNY<KUMAR.SUNNY@zeemedia.esselgroup .com>Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) 1>; Barasch, Kimberly (NIH/NIAID ) [CJ---------- (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) <Richa.sharma@zeemed ia.esselgroup .com>Subject: RE: REQUEST FOR A TV INTERVIEW ON WION TV INDIAOur pleasure. Thank you again.DavidDavid Awwad, ContractorCustomer Services Branch, NIH\NIAID\OCICBNTT DATA Services Federal , LLCPhone : (b) (6)(b)(6)Disclaimer :NIH-002004The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient. If you havereceived this e-mail in error please inform the sender and delete it from your mailbox or any otherstorage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity for anystatements made that are sender's own and not expressly made on behalf of the NIAID by one of itsrepresentatives.From: Latika Chugh {WION) <lati ka.chugh@zeemedia.esselgroup .com>Sent: Thursday, February 6, 2020 8:06 AMTo: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY<KUMAR.SUNNY@zeemedia.esselgroup .com> -------~~ Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ---------- (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) <Richa.sharma@zeemed ia.esselgro up.com>Subject : Re: REQUEST FOR A TV INTERVIEW ON WION TV INDIADavid,Many thanks for the Interview.He really added value in our show.We look forward to have his presence in future on WION.RegardsLatika ChughFrom: Awwad, David (NIH/NIAID) [C] (b)(6)Sent : Thursday, February 6, 2020 5:00 PMTo: Latika Chugh {WION) <lat ika.chugh@zeemed ia.esselgroup.com>; KUMAR SUNNY<KUMAR.SUNNY@zeemedia.esselgroup.com>Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ(b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1>; Richa Sharma _______._.... _{WION) <Richa.sharma@zeemed ia.esselgroup.com>Subject: RE: REQUEST FOR A TV INTERVIEW ON WION TV INDIAThank you much.From: Latika Chugh {WION) <lat ika.chugh@zeemedia.esselgroup.com>Sent : Thursday, February 6, 2020 6:29 AM -------~ = To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY<KUMAR.SUNNY@zeemed ia.esselgroup. com>Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ---------- (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) <Richa.sharma@zeemed ia.esselgroup .com>Subject: Re: REQUEST FOR A TV INTERVIEW ON WION TV INDIANIH-002005Dear David,It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 minutes onlyon Skype.My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now.Also, We have send you Skype Request from WION Skype Id some hours ago. I request you toplease add us.RegardsLatika ChughFrom: Awwad, David (NIH/NIAID) [CJ Cb)(Sent: Thursday, February 6, 2020 4:54 PMTo: Latika Chugh (WION) <lat ika.chugh@zeemedia.esselgroup.com>Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID) (Cl---------- (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUEST FOR A TV INTERVIEW ON WION TV INDIALet me know if you would like to connect a couple minutes earlier. I am on standby .David-----(b)(6) (cell)David Awwad, ContractorCustomer Services Branch, NIH\NIAID\OCICBNTT DATA Services Federal, LLCPhone: Cb) (6)(b)(6)Disclaimer:The information in this e-mail and any of i ts attachments is confidential and may conta in sensitiveinforma t ion. It should not be used by anyone who is not the original intended recipient. If you havereceived this e-mail in error please inform the sender and delete it from your mailbox or any otherstorage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not expressly made on behalf of the NIAID by one of itsrepresentatives.From: Latika Chugh (WION) <lat ika.chugh@zeemedia.esselgroup.com>Sent: Wednesday, February 5, 2020 9:25 AM -------oc-c- = To: Awwad, David (NIH/NIAID) [CJ" .":=:=======~~ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID) [CJNIH-002006--------- Cb)( ,>; Oplinger, Anne (NIH/NIAID) [E] --------- (b)(6) Subject: Re: REQUEST FOR A TV INTERVIEW ON WION TV INDIAThanksSee you tomorrowLatika : (b)(6) ------Get Outlook for AndroidFrom: Awwad, David (NIH/NIAID) [C] --------- (b)(6)Sent : Wednesday, February 5, 2020 7:50 :26 PMTo: Latika Chugh (WION) <lat ika.chugh@ zeemed ia.esselgroup .com>Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) [CJ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6)Subject: Re: REQUEST FOR A TV INTERVIEW ON WION TV INDIASkype Handle: Live:niaidithelp or niaidit help@outlook.comDavid: (b)(6)Sent from my iPhoneOn Feb 5, 2020, at 9:16 AM, Latika Chugh (WION)<latika .chugh@zeemedia .esselgroup.com> wrote:Yes,It completely fine with us.Our Skype Id - wion record. Please share your Skype id with us.We will be online at 7 AM ET TIME WHICH WILL BE 5:30 PM OUR TIME IN 1ST.RegardsLatika ChughProducer , WionIndiaFrom: Conrad, Patricia (NIH/NIAID) [E] --------- (b)(6)Sent: Wednesday, February 5, 2020 7:35 PMTo: Latika Chugh (WION) <latika .chugh@zeemed ia.esselgroup .com>Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, DavidNIH-002007(NIH/NIAID) [C) (b)(6J>; ,,;__;_ _ __;..;:_;.::::=:,;: (b:):(:c:6=:):>:- ____ _ Oplinger, Anne (NIH/NIAID) [E]Subje ct: FW: REQUEST FOR A TV INTERVIEW ON WION TV INDIADr. Fauci can do a skype int erview Thursday morn ing 7 am - 7:15 am ETby skype. Please let us know asap if that wo rks.Patricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. Itshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergyand Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nt made that are sender's own and notexpressly made on behalf of the NIAID by one of its representat ives.From: Latika Chugh {WION) <lat ika .chugh@zeemed ia.esselgroup.com >Sent: Tuesday , February 4, 2020 5:15 AM -------=-c-c= To: Fauci, Ant hony {NIH/NIAID ) [E] (b)(6)>Cc: Wion Guest Relations <wion.guestrelations@zeemedia.esselgroup.com>Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIADear Anthony S. Fauci,M.D., NIAID DirectorGreet ings from WION!World Is One News (WION)is an internat iona l English news channel from the ZeeMedia Group, India's premier television brand. WION is uniquely positioned as the'Global Voice of India', present ing its own perspective on international issues ofcritical significance. WION is the prefe rred channel for most opinion makers acrossthe wor ld as they happi ly attend our shows bringing in credibleviewpoints on many issues. WION is currently available in India, Indones ia, TheRepublic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia ,Singapore and South Africa etc.NIH-002008NIH-002009WION's shows have featured Indian Political scenario & global leadersspeaking on issues facing their country and the world in general.I would like to request for your time for an interview with us anytime soon todayfor 10-15 minutes. We usually conduct Interview via Skype. Request you to shareyour Skype Id.It's regarding CORONAVIRUS.Please let us know when is the best time for you to join us via Skype. Wait ing foryour confirmation.CLICK HERE TO WATCH WION LIVE :https://www .wionews.com/live -tvLive TV, News I wionews.com© 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved.www.wionews .comLook forward hearing from you .RegardsL atik a ChughWION TV , IndiaZee Disclaimer: Confidentia lity/ Proprietary Note: This communication is confidentia l/proprietary and is intended for use only by the addressee. Zee Media Corporation Ltd.accepts no responsibility for any mistransmission of, orinterference with , th iscommunicationFrom:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon, 10 Feb 2020 00:49:33 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: RE: CNN Interview CONFIRMATION: Dr. Anthony FauciThanks.From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)Se nt: Sunday, February 9, 2020 7:46 PMTo: Fauci, Anthony (NIH/NIAID) [E]-------= (b-)c(c-6-)=Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony FauciSent from my iPhoneBegin forwarded message:From: "Griffin, Janelle" <Janelle.Griffin@turner.com >Date: February 9, 2020 at 5:54:23 PM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID)[El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6),"Greene, Nyja" <Nyja.Greene@turner .com>Subject: CNN Inte rview CONFIRMATION: Dr. Ant hony FauciHello,We're all set for tomorrow! QDr. Fauci is confirmed for a live segment at 10: I Sa et on Newsroom w/Poppy Harlow & JimSciutto.Please ensure he 's seated no later than 10:0Sa et. (the show is aware that Dr. Fauci has ahard at 10:20a et)Nyja Greene , cc' d on this email , will be your Atlanta based show point of contacttomorrow.Any issues or changes please don 't hesitate to reach out to her in the morning.Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered theSARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, howbad do think this could become? How does the Coronavirus comp are/contrast with otherslike Ebola or Zika? How effective are quarantine s in situations like this? What, if any,precautions shou ld we be taking right now in America? Any thoughts /talking points you cansend ove.r from Dr. Fauci evening would be super helpful.NIH-002010Patrici a- thank you sooo much for all of your help with organizing. We really appreciate itand look forward to Dr. Fauci jo ining the show.From: Conrad, Patricia (NIH/NIAID) [E] CbH >Sent: Saturday, February 8, 2020 1:04 PMTo: Griffin, Janelle <Janelle.Gr iffin@turne r.com>Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El---------(b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony FauciOk thxSent from my iPhoneOn Feb 8, 2020, at 12:54 PM, Griffin, Janelle <Janelle.Griffin@turner .com>wrote:Great- thank you!Let's keep things for a segment at 10:lSa on Monday .I'll be back in touch after my 6p show planning conference call Sundayevening.Thank so much Patricia QFrom: Conrad, Patricia (NIH/NIAID) [El- -------- (b)(6) Sent : Saturday, February 8, 2020 12:53 PMTo: Griffin, Janelle <Janelle.Griff in@turner.com >Cc : Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer(NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E],,;_ ___ ;_;_.;..:::(:b?~H;;;;>-------Subject: Re: CNN Interview Request: Dr. Anthony FauciWe can make the 9 am hour wo rk too. Pis let us know ASAP so I can makesure our studio is available. When wi ll you have a final answer?My cell is ____ Cb_>C_6 ) and am always on email which is better for me.Sent from my iPhoneNIH-002011On Feb 8, 2020, at 12:48 PM, Griffin, Janelle<Janelle.Griffi n@turner .com> wrote:That's great- thanks Patricia !We'll add him to our calendar for 10:lSa et.If we needed to move him his segment to the 9a et hour wouldthat also work?May I have your cell number for my records?From: Conrad, Patricia (NIH/NIAID) [E](b)(6)>Sent: Saturday, February 8, 2020 12:46 PMTo: Griffin, Janelle <Janelle.Griffi n@tu rner .com>Subject: Fwd: CNN Interv iew Request: Dr. Anthony FauciHi JanelleWe can make this work - it would need to be from between 10am - 1020 am hard stop.Will that work?It wou ld need to be from our NIH Readycam studio withVideol inkLet me know if that worksFrom: Griffin, Janelle<Janelle.Griffin@turne r.com>Sent: Saturday, February 8, 2020 11:33 AMTo: Fauci, Anthony (NIH/NIAID) [E](b)(6)Subject: CNN Interview Request: Dr. AnthonyNIH-002012NIH-002013FauciImportance: HighGood morning Dr . Fauci ,I hope this email finds you doing well .I'm reaching out on behalf of Newsroom w/PoppyHarlow & Jim Sciutto hoping you can join for aninterview .Are you available to join CNN this MondayFebmary lOth in the 10a et hour?This would be live for about 5-7 minutes to discussdevelopments regarding the coronavirns.Please feel free to contact me via email or at (404)452- 7769 to let me know.Thanks for your time - I look fo1ward to hearingfrom you soo n.Janelle Griffin-ButtsEditorial Producer, CNNEmail: janelle .griffin@turner.com I Twitter:@janellegCNNFrom:Sent :To:(b)(6)Sun, 9 Feb 2020 16:36:38 -0500autotell ISubject: Re: Help Re: Novel Rx for CoronavirusThanks, Andy.Best regards,TonyOn Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote:Thank you my friend, hope it leads to something good for patients and the public .I was at a meeting of the "Philosophical Society of Texas" this week end and meet with alot of Bush alums like Don Evans and Margaret Spellings etc and Margaret wascommenting on the coronavirus scare and how fortunate we are to have you there at NIHlooking after us!! If you ever decide to relocate to Texas you have a fan club here!All my bestAndyFrom: Fauci, Anthony (NIH/N IAID) [E]- ------- (b)( > Sent: Sunday, February 9, 2020 7:24 AMTo: autotell I CbC) >Subje ct: RE: Help Re: Novel Rx for Coronav irusAndy:Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it bythe peop le here at NIAID who are r unning the nCoV research initiative. I will getback to you with their and my assessment. I hope that all is well with you. We aredoing a lot of late nighters here . Feels like my internship. DDBest regards,TonyFrom: autotell I Cb)( >Sent: Friday, February 7, 2020 2:50 PM ------~= To: Fauci, Anthony (NIH/NIAID} [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E)(b )( 6) >Cc: Xiaokui Zhang--------(b)(6) >; Robert Hariri(b)(6)>Subject : Help Re: Novel Rx for CoronavirusTonyNIH-0020 19Greetings . Always proud to see you at the White House (with Alex) leading the fightagainst th is latest infect ious disease threat (b)( 4)(b) (4)I trust this email finds my Paisano happy and content as you cont inue to be a gift to thisnation and the world. Please let me know you received this email.My best to you and your family . Hope our paths cross soonAndyNIH-002020From:Sent :To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 2020 18:23:24 +0000Folkers, Greg (NIH/NIAID) [E]RE: lnvestigational compound remdesivir, developed by UAB and NIHresearchers, being used for treatment of novel coronavirusWOW! I did not know that. Good talking point for press conferences.From: Folkers, Greg (NIH/N IAID) [E) (b)(6)Se nt: Sunday, February 9, 2020 1:13 PMSubject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used fortreatment of novel coronaviruslnvestigational compound remdesivir, developed by UAB andNIH researchers, being used for treatment of novelcoronavirusby Savannah Koplon• February 07, 2020• Print• Email___ --- - ,Richard Whitley, M.0., Distinguished Professor at UAB and principal investigatorof the U19 grantThe investigationa l drug remdesivir, developed through research conducted through the Ant iviral DrugDiscovery and Development Cent er, or AD3C, and centered at the University of Alabama at Birmingham,is being used to treat select infected patients in the United States and in China who have been affectedby the outbreak of novel coronavirus (2019-nCoV).UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Instit ute of Allergy andInfectious Diseases Centers of Excelle nce for Translat ional Research to study and develop treatment forhigh-priority emerging infections. Work has been taking place in earnest to develop drugs for emerginginfluenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARS and MERS, andalphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi -NIH-002021NIH-002022institutional collaboration to accelerate drug discovery for these emerging infections and is a publicprivatepartnership between academic institutions and Gilead Sciences.Remdesivir, developed to treat the coronavirus causing MERS, was found to have significant activ ityagainst the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly,remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS andSARS in cell culture and animal models . Based on the compassionate plea requests of treating physiciansin the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug hasnot yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety andefficacy studies is a major accompl ishment for the AD3C - namely the U 19 grant - as it shows significantand swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreakson an international scale and, importantly, to anticipate the introduction of these infections in theUnited States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator ofthe U19 grant.WATCH: UAB inf ectious disease experts prov ide info rmat ion on the 2019 novel coronav irus.Gilead Sciences and supporting researchers and clinicians are working with health authorities from theWorld Health Organization and in China to establish a placebo-controlled study to determine whetherremdesivir is safe and effective in treating 2019-nCoV."This is a prime example of how the research weare conducting at UAB plays a critical role intreating patients on a global scale and ourcontribution of substantial scientific advances."- Richard Whitley, M.D., UAB DistinguishedProfessor"The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and theUniversity of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of ourcollaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwidefight 2019-nCoV. This is a prime example of how the research we are conducting at UAB plays a criticalrole in treat ing patients on a global scale and our contribution of substantial scientific advances,"Whitley continued .Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partnerswi ll need to build backup molecules for potential testing and treatment in the near future.The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency ofinternational concern ."UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experiencedin virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease fromUAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , TheUniversity of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, theUniversity of Colorado, Denver, and Oregon Health & Science University.Disclaim er: Any third-party material in this email has been shared for internal use under fai1· use provision sof U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily representmy views nor those of NIAID, NIH, HHS, or the U.S. gover nment.From:Sent :To:Cc:Subject:Attachme nts:Liz:Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 2020 18:20:45 +0000Liz SzaboConrad, Patricia (NIH/NIAID) [E]RE: Plumbing as possible means of spread of coronavirusesAmoy Gardens and SARS.pdfThanks for the note . I do not know enough about the plumbing system on the cruise ships tomake any meaningful comments, certain ly not any comments that could be att ributable tome. And so, I will pass on this one, The best person to comment or opine on this would beMart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the originalNEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS.Best regards,TonyFrom : Liz Szabo <LSzabo@kff.org>Sent: Saturday, February 8, 2020 7:21 PM ------ ~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: Plumbing as possible means of spread of coronavirusesHI Dr. Fauci,I hope you're doing well. I know you must be very busy.Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might bespreading through plumbing on the cruise ship? She sent me these links, below, about howplumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in HongKong. Libby lived in China during the SA.RS outbreaks and remembers that the sinks there don'thave the typ ical U-bend trap that sinks have here, which allows sewer gases and unpleasantodors to come through.If plumbing is a risk for spreading coronavimses, what could be done to protect passengers oncruise ships?T'd love to hea r your thoughts on this, even if just by email.Thanks for your time.Liz SzaboKaiser Health News571-201-9009https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/NIH-002023NIH-002024https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm lhttps://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-diseasehttps:/ /jamanetwork .com/journals / jama/fullarticle /27 61044 ?guestAccessKey=f6 l bd430-07 d8-4b 86-a 7 49-bec05bfffb65&utm source=For The Media&utm medium=referral&utm campaign =ftm links&u tm content=tfl&utm tenn =020720From: Fauci, Anthony (NIH/NIAID) [E)Sent : Sun, 9 Feb 2020 17:59:10 +0000To: Tabak, Lawrence (NIH/OD) [E)Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia(NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea(NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6))Subject: RE: NCATs request re. CoronavirusLarry'-: -------------------------------, ("b~'"("S')Best,TonyFrom: Tabak, Lawrence (NIH/OD) [E) --------- (b)(6)> Sent: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID). .[E;l; ...;.:...:::==(=b)(=6) :~=----- Cc: Schwetz, Tara (NIH/OD) [El --------- (b)( > Subject : NCATs request re. CoronavirusTon' '-------------------------------~ ~ (b) (5)Thanks,LarryNIH-002025From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 202017:53:04 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony FauciOK. Thanks.From: Conrad, Patricia (NIH/NIAID) [El (b)(6)>Se nt: Sunday, February 9, 2020 12:44 PMTo: Fauci, Anthony (NIH/NIAID) [E]-------= (b-)c(c-6-)=Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony FauciI am working on this.Sent from my iPhoneBegin forwarded message:From: "Varon, Sophie" <Sophie.Varon@turner.com >Date: February 9, 2020 at 12:30:31 PM EST -------~= To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Fauci, Anthony(NIH/NIAID) [El" (b)(6)Subject : CNN Anderson Cooper Full Circle Request- Dr. Anthony FauciHello Dr. Fauci and Patricia ,I hope you're both doing well.I'm reach ing out to see if Dr. Fauci could be available for an interview withAnderson Cooper on Monday for his CNN digit al program, Full Circle . Full Circleis an intere sting platform because it allows us to take live viewer questions . Thistaped interview would air on Tuesday at 5PM and Anderson could tape tomorrow inthe 4PM hour or after 5:45PM.The topic is of course the Corona virus.Thank you for considering this request!Sophie VaronEd itorial Producer , CNN AC360cell- (bHNIH-002026From:Sent :To:Subject :Fauci, Anthony (NIH/NIAID) [E)Sun, 9 Feb 2020 17:52:22 +0000Conrad, Patricia (NIH/NIAID) [E)FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony FauciIf we can do this, I would be happy to.From: Varon, Sophie <Sophie.Varon@turner .com>Sent: Sunday, February 9, 2020 12:30 PM -------~ = To: Conrad, Patricia (NIH/ NIAID) (E] --------- (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] (b)(6)Subject: CNN Ande rson Cooper Full Circle Request- Dr. Anthony FauciHello Dr. Fauci and Patricia ,I hope you're both doing well.I'm reaching out to see if Dr. Fauci could be ava ilable for an interview with Ande rson Coope r onMonday for his CNN digital program, Full Circle. Full Circle is an interes ting platform becauseit allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM andAnderson could tape tomorrow in the 4PM hour or after 5:45PM .The top ic is of course the Coronavirus.Thank you for cons idering this request!Sophie VaronEditorial Producer , CNN AC360cell (b)(6)NIH-002027From:Sent :To:Fauci, Anthony (NIH/NIAI0) [E)Sun, 9 Feb 202017:5 1:21 +0000Hall, Bill (HHS/ASPA)Subject: FW: CNNI Interview with Dr. Anthony Fauci,Bill:Th is link below is for an interview that I gave for CNN International this morning . As we allknow, it makes such a big difference when the interviewer knows the subject and asks goodquestions that this interviewer did. Would that they were all like her.Best regards,TonyFrom: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Sent : Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)>Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J>Subject: RE: CNNI Interview Request: Dr. Anthony Fauci,We are so glad to!Here is the clip https:ljwe .tl/t -BOkVJSyQVBAl I the best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [El- -------- (b)(6)> Sent: 09 February 2020 16:15To: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: Re: CNNI Interview Request: Dr. Anthony Fauci,My pleasure- so glad we could make it wor k. Please do send us the the video segmentBest,Patty .Sent from my iPhoneOn Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) <Joanna.Hynds@turner .com> wrote:Dear Mr Fauci,NIH-002028I just wanted to thank you for your accommodation at such short not ice for the earlierinterview. I do apologise for the miscommunication on my part.We really enjoyed having you on the show!Thanks too to Patricia, for helping coordinate this all at last minute.I hope you both have a great evening.Many thanks again for your patience and understanding.If you would like a video segment of your hit I will gladly send you it on request.Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [E] (b)(6)Sent: 09 February 2020 14:26To: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Cc: Pfeifer, Hazel <Hazel.Pfeife r@turner.com >; Lovejoy, Hannah (NE) <H ann ah.Lovejoy@ turner .com>; Fauci, Anthony (NIH/NIAID) [E] ------------=---c---=(-b)(6)> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci,Do you have the hit time and contact info please send ASAP.Sent from my iPhoneOn Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE)<Joanna.Hynds@turner .com> wrote:Perfect - we really appreciate this.I will get you these deta ils ASAP.Does Dr Fauci need a car?Best,JoannaNIH-002029From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)>Sent: 09 February 2020 13:33To: Hynds, Joanna (NE) <Joanna.Hynds@turner.com >Cc: Pfeifer, Hazel <Hazel.Pfeifer@turner.com >; Lovejoy, Hannah (NE)<Hannah.Lovejoy@turner.com >; Fauci, Anthony (NIH/NIAID) [E](b)(6)Subject: Re: CNNI Interview Request: Dr. Anthony Fauci,Adding Dr Fauci hereHe can come to the WDC CNN studio. Please send us the exact live hit time aswell as the studio address and on-site contact name, number and cell numberASAP. Dr Fauci cell is (b)(6)and you have mine.Thank you .Sent from my iPhoneOn Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE)<Joanna.Hynds@turner.com > wrote:Dear Patricia,Just following up from our phone conversation , unfortunately Iwon't be able to facilitate a StudioGo t ruck for this interview.We are still really keen to get Dr Fauci on the show-w ill he beable to come to the bureau?I will be able to book him a car if he needs.Let me know what suits,Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [E](b) ~ >Sent: 09 February 2020 13:00To: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Subje ct: Re: CNNI Interview Request: Dr. Anthony Fauci,NIH-002030For the t rick- the location is northwest Washington DC. NearAmerican university.Sent from my iPhoneOn Feb 9, 2020, at 7:51 AM, Conrad, Patricia{NIH/NIAID) [El (b)(6)> wrot e:Please call me ASAP at -----(b)(6)for this request.Sent from my iPhoneBegin forwarded message:From: "Fauci, Anthony (NIH/NIAID)[El" CbC) >Dat e: February 9, 2020 at 7:08:54AM ESTTo: "Conrad, Patr icia (NIH/NIAID) [E]"(b)(6)Subject: Fwd: CNNI InterviewRequest: Dr. Anthony Fauci,Sent from my iPhoneBegin forwarded message:From: "Hynds, Joanna(NE)"<Joanna.Hynds@turner.com>Date : February 9, 2020at 6:06:15 AM ESTTo: "Fauci, Anthony(NIH/NIAID) [El"(b)(6)>Cc: "Tejera, Isabel{Intern)"<isabel.Tejera@turner.com>, "Lovejoy, HannahNIH-002031NIH-002032(NE)"<Hannah.Lovejoy@turner.com>Subject: CNNIInterview Request: Dr.Anthony Fauci,Dear Dr Fauci,I hope you are well! Iam reaching out fromCNN International toenquire if you areavailable today to joinus on Connect theWorld at llaET todiscuss the coronavirus.Might this be apossibility? It would begreat to arrange this.Background on CNN• CNNInternationalreaches morethan 250millionhouseholdsworldwideincluding in theUS via DIRECTV.• CNNInternational isthe numberoneinternationalTV newschannelaccording to allmajor mediasurveys acrossEurope, theMiddle East andAfrica, the AsiaBest,Pacific regionand LatinAmeric a.• In September2019 CNN.comhad 162 millionunique readersglobally permonth and 114million mobilereaders amonth, leadingthe BBC, Yahooand New YorkTimes.Joanna HyndsPlanning DeskCNN Intern ation al+ 44 207 693 1640(office)+ (b)(6) ( cell)joanna.hynds@turner.com<image0O1.png>Information in thisemai l including anyattachments may beprivileged orconfidential and isintended exclusively forthe addressee. Theviews expressed maynot be official policy,but the personal viewsof the orig inator . If youhave received this emailin error, please notifythe sender by return emailand delete it fromyour system . Youshould not reproduce,distr ibute, store,NIH-002033NIH-002034retransmit, use ordisclose its contents toanyone. Please note wereserve the right tomonitor all e-mailcommunicat ionthrough our internaland external networks.Turner and the Turnermarks are trade marksof Turner BroadcastingSystem Inc and areused under licence.Turner BroadcastingSystem Europe Limited(Company No.1927955), TurnerEnterta inmentNetworks Internationa lLimited (Company No.2803512), TurnerBroadcasting SystemHoldings (Europe)Limited (CompanyNumber 2802926) andCable NewsInternationa l Limited(Company No.5001368) areincorporated in Englandand Wales and sharethe same registeredoff ice at Turner House,16 Great MarlboroughStreet, London WlF7HS.Information in th is email including any attachments may beprivileged or confident ial and is intended exclusively for theaddressee. The views expressed may not be official policy, butthe personal views of the or iginator. If you have received th isemail in error, please not ify the sender by return e-mail anddelete it from your system . You should not reproduce,distribute, store, retransmit, use or disclose its contents toanyone . Please note we reserve the right to monitor all e-mailcommun ication through our internal and external networks.NIH-002035Turner and the Turner marks are trade marks of TurnerBroadcasting System Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No.1927955), Turner Entertainment Networks Internat ional Limited(Company No. 2803512), Turner Broadcasting System Holdings(Europe) Limited (Company Number 2802926) and Cable NewsInternat ional Limited (Company No. 5001368) are incorporatedin England and Wales and share the same registered office atTurner House, 16 Great Marlborough Street, London Wl F 7HS.Informat ion in this email includ ing any attachments may be privileged orconfidential and is intended exclusively for the addressee. The viewsexpressed may not be officia l policy, but the personal views of the originator .If you have received th is email in error, please notify the sender by return emailand delete it from your system. You should not reproduce, distribute ,store, retransmit, use or disclose its contents to anyone. Please note wereserve the right to monitor all e-mail communication through our interna land externa l networks . Turner and the Turner marks are trade marks ofTurner Broadcasting System Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No. 1927955), TurnerEnterta inment Networks Internationa l Limited (Company No. 2803512),Turner Broadcasting System Holdings (Europe) Limited (Company Number2802926) and Cable News Internat ional Limited (Company No. 5001368) areincorporated in England and Wales and share the same registered office atTurner House, 16 Great Marlborough Street, London WlF 7HS.Information in th is email including any attachments may be priv ileged or confidentia l andis intended exclusively for the addressee. The views expressed may not be off icial policy,but the personal views of the originator. If you have received th is email in error, pleasenotify the sender by return e-mail and delete it from your system. You should notrep roduce, distr ibute, store, retransm it, use or disclose its contents to anyone. Please notewe reserve the right to monitor all e-mail communicat ion through our internal andexterna l netwo rks. Turner and the Turner marks are trade marks of Turner BroadcastingSystem Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No. 1927955), TurnerEntertainment Netwo rks Internat ional Limited (Company No. 2803512), TurnerBroadcasting System Holdings (Europe) Limited (Company Number 2802926) and CableNews Internat ional Limited (Company No. 5001368) are incorporated in England andWales and share the same registered off ice at Turner House, 16 Great Marlborough Street,London WlF 7HS.Informat ion in this email includ ing any attachments may be privileged or confident ial and is intendedexclusively for the addressee. The views expressed may not be off icial policy, but the personal views ofthe originator . If you have received this email in error, please not ify the sender by return e-mail andNIH-002036delete it from your system. You should not reproduce, distribute, store, retransmit , use or disclose itscontents to anyone. Please note we reserve the right to monitor all e-mail communication through ourinternal and external networks . Turner and the Turner marks are trade marks of Turner BroadcastingSystem Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment NetworksInternational Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited(Company Number 2802926) and Cable News International Limited (Company No. 5001368) areincorporated in England and Wales and share the same registered office at Turner House, 16 GreatMarlborough Street, London WlF 7HS.From:Sent :To:Subject :Fauci, Anthony (NIH/NIAID) [E)Sun, 9 Feb 2020 17:34:16 +0000Denise OberRE: HEART WRENCHING QUESTION! WillThe State Department and CDC travel alerts for China, which advise only absolutely essential travel, do notofficially include Hong Kong and so there is no official restriction right now (but this could change), and there is noquarantin e requir ement upon returning from Hong Kong. However, thi:; all could change quickly . (b)(6)-----Original Message-----From: Denise Ober ;;-- ------- (b~)~(=6)Sent: Saturday , February 8, 2020 3:23 -PM-- --- --:,,:,~ To: Fauci, Anthony (NIH/NIAJD) [E] -------- (b)(6) > Subject: HEART WRENCHING QUESTION1 WODear Dr. Fauci,l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busyand so very importantly needed at this time. I do apologize for taking even a moment from your high demandschedule. But thought I'd try to reach out anyway in case you did see this.l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge aboutthe coronavirus thus far if ou had lanned to travel to Thailand mid March via stop over at Hon Kono-would ou?Thank you from my concerned heart!Thank you for EVERYTHING you do and have done in the past!Best to you,Denise OberSent from my iPadNIH-002037(b)(6)From: Fauci, Anthony (NIH/NIAID) [ElSent: Sun, 9 Feb 2020 17:26:01 +0000To: Cassetti, Cristina (NIH/NIAID) [ElCc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers--------- (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E]Subject: FW: Help Re: Novel Rx for CoronavirusAttachments: __ C_b>_C_4) in 2019-CoV Proposal 07Feb2020.docxCristina :This is not jus t your ordinary person writing to us. This is Dr. Andrew von Eschenbach, formerDirector of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit;however, please have someone go over it carefully and put together a response. Also, only ifappropriate, and feasible, see if there is any way we can be of assistance to him. Th anks.Best regards,TonyFrom: autotell I ----------- (b)(6)Sent: Friday, February 7, 2020 2:50- P-M-- --~~ To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b )( 6)_Cc_: X_ia_ok_ui Zha.n.g.. ::.===~~------(b) (6) >; Robert Hariri ---------- (b )( 6)(b)(6)Subject: Help Re: Novel Rx for CoronavirusTonyGreet ings. Always proud to see you at the White House (with Alex) leading the fight against this latestinfect ious disease threat. Cb) (4)(b) (4)I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and theworld. Please let me know you received this email.My best to you and your family. Hope our paths cross soonAndyNIH-002038From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 202017:17:07 +0000Stover, Kathy (NIH/N IAID) [ElCc:(NIH/NIAID) [ElSubject:Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, GregRE: FOR ASF REVIEW: Draft responses to questions from Italian news agencySee my edits in red.From: Stover, Kathy (NIH/NIAID) [E] (b)(6)>Sent: Friday, February 7, 2020 2:02 PMTo: Fauci, Anthony (NIH/NIAID) [El------ (=b)'"("=6' )>Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E)---------- (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject : FOR ASF REVIEW: Draft responses to questi ons from Italian news agencyHi Dr. Fauci,Below are draft responses to questions from a reporter with the Italian news agency ANSA.Please let me know if you have any suggested edits, and I'll move it along.Thanks,KathyEnrica BattifogliaScience and Technology Head EditorANSA news agency (Italian news)Enrica .Batt ifogl ia@ansa .itExpected place of publication: ANSA Science web page (www .ansa.it/scienza )Dear Professor Fauci ,I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure tointerview you several times at the AIDS world conferences.I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on theANSA Science web page (www.ansa.it/scienza ), the main online science news resource in Italywith over 1.5M contacts each month. I am sure that your clarity and competence will be highlyvaluable to put some much-needed order among so many contrasting news and data, and wouldbe much appreciat ed by our readers .NIH-002039NIH-0020401. Do the current available data allow to understand the threat level of coronavirus 2019-nCoV in terms of both lethality and diffusion speed, and about the possible evolutionscenarios of the disease?There is much that we do not know about the novel coronav irus. Curre ntly, there have been morethan 37,000 confirmed cases in China, and China has reported more than 800 deaths. As youknow, there have been three confirmed cases in Italy to date. The reported case fatality rate(lethality) among the 37,000 cases that have come to the attention of the health care systemis 2%. However , given that there are likely many more cases that are without symptomsor with minimal symptoms, the actual death rate is probably lower than 2%.It is impossible to predict how the virus will evolve. It is our hope that the extraordinarycontainment measures that China has implemented will help prevent the outbreak frombecoming a global pandemic. But given that the virus is present in 27 countr ies to date and canbe transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic .2) What exactly do we know about its modes of transmission, especially from people whodo not yet have the symptoms?Again, there is much that we do not know about the novel coronavirus, including its specifictransmission abilities. Based on initial findings that have been reported, we suspect itstransmission is similar to influenza and other respiratory viruses, namely that is transm ittedthrough respiratory droplets when an infected person coughs or sneezes, and by touchingsurfaces, such as door handles, that recently have virus on them and then touching your face.There have also been reports that the virus is present in feces and vomit. However, it is stilluncertain that the virus can be transmitted through this route.Traditionally, most viruses are transmitted when someone has symptoms. With the novelcoronavirus; however, there appears to be asymptomatic transmission occurring. We do notknow how many cases are being driven by asymptomatic transm ission or by those withsymptoms . Typically, viruses are largely transmitted by infected peop le experiencing symptoms.3) Are the genetic sequences provided by China enough to start working on a vaccine?The genet ic sequences provided by China enabled researchers to quickly develop a diagnosticthat is being used to dete1mine whether someone is infected with the novel coronavirus. Thegenetic information has also been useful in work to develop a preventive vaccine. The NationalInst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, isbuilding on its experience with the SARS and MERS corona viruses to better understand the virusas well as develop and test rapid point-of-care diagnostics , vaccines and treatments, includingbroad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we areNIH-002041working with the biotechnolog y company Moderna and the Coalition for Epidemic PreparednessInnovation (CEPI) to develop a "messenger RNA" vaccine for the novel coronav irus. Othercountries and companies are working to develop a vaccine as well.4) What are the technical times to develop a working vaccine in terms of scientific research,and what are the approx times for the necessary legal certifications, and for industrialproduction and distribution?In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having anexperimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinicaltrial will involve administering the vaccine to a small number of healthy adults in the UnitedStates to see if it is safe and has some ability to induce an immune response. If that is successfuland the outbreak has not ended, we will move to a larger Phase 2 clinical trial with theexpectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. Ifefficacious, it will still take additional months to produce enough vaccine to distributewidely ..In addition to this vaccine, NIAID is also supporting scientists and companies to develop othervaccine candidates.5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the Eastin the last 20 years and in 2009 the virus responsible for the flu pandemic too did comefrom China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events?To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China.Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent theunknown from occurring in the first place. What we can do is learn as much as we can aboutemerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics,treatments and vaccines to protect against infection.From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sun, 9 Feb 2020 16:41:33 +0000To: Conrad, Patricia (NIH/NIAID) [ElSubject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel -March 2, 2020 in BostonPlease RSVP no.From: Scala, Steve <Steve.Scala@cowen.com>Se nt: Sunday, February 9, 2020 11:39 AM ------~~ To: Fauci,A nthony (NIH/NIAID) [El- ------- (b)(6) Cc: Nadeau, Phil <Phil.Nadeau@cowen.com>; Miner, Kathy <Kathy.Miner@cowen.com>; Nedelcovych,Michael <Michael. Nedelcovych@cowen.com>Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 inBostonHi Dr. FauciI am a pharmaceutical industry analyst at Cowen and Company, a New York City basedinvestment company that specializes in health care. Each year we host a Health CareConference in Boston in March that attracts 200+ companies and 1000+ investors. During thisyear's conference, we had planned to host a one-hour panel discussion on the evolution of andreforms within the China Health Care System and China Pharmaceutical market. However,given global concerns around Coronavirus, we have decided to focus the panel instead on thevirus and the outlook for emerging treatments. This perspective is critical to health carecompanies and therefore the institutions that invest in them.Our panel will take place during Cowen's 40th Annual Health Care Conference, which will beheld at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel onMonday morning, March 2nd, between 9:05-10:0SAM. Attendees at our conference includeinstitutional investors from insurance companies, mutual funds, pension funds, banks, andother types of funds, mainly in the U.S. and EU.Cowen would provide you an honorarium for your time during the one-hour panel. We proposean honorarium of $1,500, and we reimburse conference-related travel expenses.The discussion will be Q&A only and no presentation on your part is requested .We look forward to hearing from you.Sincerely,Steve ScalaNIH-002042NIH-002043In line with best practices suggested for brokerage firms, Cowen has a policy regarding ourinteraction with subject matter experts such as yourself, and by accepting and participating inthis engagement, you agree to the conditions of this policy, including that you will notknowingly disclose any material non-public and/or confidential information; that your currentemployer permits you to participate in our event; that you are not employed by any of thecompanies anticipated to be discussed; and that your participation will not cause you toknowingly violate any contract (e.g., employment contract or consulting contract), agreement(e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board ofdirectors) that you may have.COWENSteve ScalaPharmaceut ical Industry AnalystEquity ResearchCowen and Company , LLCTwo Internat ional Place, 28th Fl.Boston , MA 02110617-946-3923steve.sca la@cowen.comwww.cowen.comThis message and any attachments are confident ial. If you are not the intended recipient, please notif ythe sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. Allemail sent to or from our system is subject to review and ret ention . Nothing contained in this email shallbe considered an offer or solicitation with respect to the purchase or sale of any securit y in anyjurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of itsaffiliates ("Cowen") represent that any of the information contained herein is accurate, complete or upto date, nor shall Cowen have any responsibility to update any opinions or other information containedherein .From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 2020 16:41:04 +0000Folkers, Greg (NIH/NIAID) [E]Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E]RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2amDefinitely for the Director's pageFrom: Folkers, Greg (NIH/N IAID) [E) (b)(6)Se nt: Sunday, February 9, 2020 9:45 AMSubject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2amIs the Coronavirus the next global pandemic or will the disease be eradicated in a short period oftime? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need toknow about the Coronavirus crisis.Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessarily representmy views nor those of NIAJD, NIB , HHS, or the U.S. government.NIH-002044From:Sent:To:Cc:(b)(6)Sun, 9 Feb 2020 10:53:02 -0500Conrad, Patricia (NIH/NIAID) [ElSubject :Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [ElFwd: CNNI Interview Request: Dr. Anthony Fauci,DoneBegin fo1warded message:From: "Hynds, Joanna (NE)" <Joanna.Hynds@tumer.com>Date: February 9, 2020 at 9:49:2 1 AM ES-T- ---------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6)Cc: "Pfeifer, Hazel" <Hazel.Pfeifer@tumer.com >, "Lovejoy , Hannah (NE)"<Hannah.Lovejoy @tumer.com >, "Fauci, Antho ny (NIH/N IAID) [E]"(b)(6) >Subject: RE: CNNI Interview Request: Dr. Anthony Fauci,Hi Patricia,I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up.DC Number: +l 2025100172 .Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [El (b)(6)>Sent: 09 February 2020 14:42To: Hynds, Joanna (NE) <Joanna.Hynds@turner.com>Cc: Pfeifer, Hazel <Hazel.Pfeife r@turner.com>; Lovejoy, Hannah (NE) ------"-="'""C"-='I <Hannah.Lovejoy@turner.com> ; Fauci, Anthony (NIH/NIAID) [El -------- (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci,We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ET so ifyou can have someone meet him at the entrance lobby to get him upstairs quickly thatwould be helpful.Sent from my iPhoneNIH-002045On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE)<Joanna.Hynds@turne r.com>wrote :Hi Pat ricia,That would be perfect. I am so sorry on the miscommun icat ion on my part.We really appreciate you accommodating us at this short notice .Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>Sent: 09 February 2020 14:35To: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Cc: Pfeifer, Hazel <Hazel.Pfeifer@t urner .com>; Lovejoy, Hannah (NE)<Hannah.Lovejoy@turner .com>; Fauci, Anthony (NIH/NIAID) [E](b)( >Subject : Re: CNNI Interview Request: Dr. Anthony Fauci,Dr DrFauci can be there for a 1030 am hitWe need to know ASAP if this is firm and what the exact hit timeSent from my iPhoneOn Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE)<Joanna.Hynds@turne r.com>wrot e:Just wanted to let you know the Flash Studio will be DC G StudioCAM23Our Bureau Address is820 First ST NE20002 WashingtonPlease contact the bureau at +1-202-898-7911NIH-002046Please arrive at 10.40, you will be on around 11 - 1 will updatewith exact hit time as soon as I have it.Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [E)(b)(6)>Sent: 09 February 2020 13:33To: Hynds, Joanna (NE) <Joanna.Hynds@turner .com>Cc: Pfeifer, Hazel <Hazel.Pfeife r@turner .com>; Lovejoy, Hannah(NE) <Hannah.Lovejoy@turne r.com>; Fauci, Anthony(NIH/NIAID) [E] (b)(6)Subject: Re: CNNI Interview Request: Dr. Anthony Fauci,Adding Dr Fauci hereHe can come to the WDC CNN studio. Please send us the exactlive hit time as well as the stud io address and on-site contactname, number and cell numbe r ASAP. Dr Fauci cell is (b)(- and you have mine.Thank you.Sent from my iPhoneOn Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE)<Joanna.Hynds@turner .com>wrote:Dear Pat ricia,Just following up from our phone conversation,unfortunately I won't be able to facilitate aStudioGo truck for this interview .We are still really keen to get Dr Fauci on the show- will he be able to come to the bureau?I will be able to book him a car if he needs.Let me know what suits,NIH-002047Best,JoannaFrom: Conrad, Patricia (NIH/NIAID) [E](b)(6)>Sent : 09 February 2020 13:00To:H ynd~Joanna(NE)<Joanna.Hynds@turner .com>Subject : Re: CNNI Interview Request: Dr. AnthonyFauci,For the trick- the location is northwest WashingtonDC. Near American university.Sent from my iPhoneOn Feb 9, 2020, at 7:51 AM, Conrad,Patricia (NIH/NIA ID) [E)--------- (b)( >wrote:Please call me ASAP at -----(b)(6) for this request.Sent from my iPhoneBegin forwarded message:From: "Fauci, Anthony(NIH/NIAID) [El"(b)(6)Date : February 9, 2020at 7:08:54 AM ESTTo: "Conrad, Patricia(NIH/NIAID) [El"(b)(6) • Subject: Fwd: CNNIInterview Request: Dr.Anthony Fauci,NIH-002048Sent from my iPhoneBegin forwardedmessage:From:"Hynds,Joanna(NE)"<Joanna.Hynds@turner .com>Date :February9, 2020 at6:06:15AM ESTTo: "Fauci,Anthony(NIH/NIAiD) [E]"(b)(6) -■ Cc:"Tejera,Isabel(Intern)"<isabel.Tejera@turner.com >,"Lovejoy,Hannah(NE)"<Hannah.Lovejoy@turner .com>Subject:CNNIInterviewRequest:Dr.AnthonyFauci,NIH-002049NIH-002050Dear DrFauci,I hope youare well! Iamreachingout fromCNNlnternational toenquire ifyou areavailabletoday tojo in us onConnectthe Worldat llaETto discussthecoronavirus.Might thisbe apossibility? It wouldbe greatto arrangethis.Backgroundon CNN• CNNInternationalreachesNIH-002051morethan250miIiionhouseholdsworIdwideincludingintheusviaDIRECTV.• CNNInternationalistheNIH-002052numberoneinternationalTVnewschanneaccordingtoallmajormediaSUrveysacrossEuropetheMiddNIH-002053leEastandAfrica,theAsiaPacificregionandLatinAmerica• InSeptember2019~NN.comhad162miIiionNIH-002054uniquereadersgloballypermonthand114miIiionmobilereadersamonthleadingtheBBC,Yaho0andBest,Jo annaHyndsNewYorkTimesPlanningDeskCNNInternational+ 44 207693 1640( office)(b)(6)~ (cell)joanna.hynds@turner.com<imageOO1.png>lnformation in thisemailincludinganyattachments maybepriv ilegedorconfidential and isintendedexclusive lyfor theaddresseeNIH-002055NIH-002056. Theviewsexpressedmay notbe officialpolicy, butthepersonalviews oftheoriginator.If youhavereceivedthis emailin error ,pleasenotify thesender byreturn emailanddelete itfrom yoursystem .Youshould notreproducedistribute,store,retransmit, use ordiscloseitscontentsto anyone .Pleasenote wereservethe righttomonitorall e-mailcommunicationthroughourinternalNIH-002057andexternalnetworks.Turnerand theTurnermarks aretrademarks ofTurnerBroadcasting SystemInc andare usedunderlicence.TurnerBroadcasting SystemEuropeLimited(CompanyNo.1927955),TurnerEntertainmentNetwo rkslnternat ionalLimited(CompanyNo.2803512),TurnerBroadcasting SystemHoldings(Europe)Limited(CompanyNumber2802926)and CableNewslnternat ionalNIH-002058Limited(CompanyNo.5001368)areincorporatedinEnglandand Walesand sharethe sameregisteredoffice atTurnerHouse, 16GreatMar lboroughStreet,LondonWlF 7HS.Informat ion in this emai l including anyattachments may be privileged or conf identia l andis intended exclusively for the addressee. Theviews expressed may not be official policy, but thepersonal views of the or iginator. If you havereceived this email in error , please not ify thesender by return e-mail and delete it from you rsystem. You should not reproduce, distribute ,store, retransmit, use or disclose its contents toanyone. Please note we reserve the right tomonitor all e-mail communication through ourinternal and external networks . Turner and theTurner marks are trade marks of TurnerBroadcasting System Inc and are used underlicence.Turner Broadcasting System Europe Limited(Company No. 1927955), Turne r Enterta inmentNetworks Internationa l Limited (Company No.2803512), Turner Broadcasting System Holdings(Europe) Limited (Company Number 2802926) andCable News International Limited (Company No.5001368) are incorporated in England and Walesand share the same registered off ice at TurnerNIH-002059House, 16 Great Marlborough Street, London WlF7HS.Information in this email including any attachments may beprivileged or confidential and is intended exclusively for theaddressee. The views expressed may not be official policy, butthe personal views of the originator. If you have received thisemail in error, please notify the sender by return e-mail anddelete it from your system. You should not reproduce,distribute, store, retransmit, use or disclose its contents toanyone. Please note we reserve the right to monitor all e-mailcommunication through our internal and external networks.Turner and the Turner marks are trade marks of TurnerBroadcasting System Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No.1927955), Turner Entertainment Networks International Limited(Company No. 2803512), Turner Broadcasting System Holdings(Europe) Limited (Company Number 2802926) and Cable NewsInternational Limited (Company No. 5001368) are incorporatedin England and Wales and share the same registered office atTurner House, 16 Great Marlborough Street, London WlF 7HS.Information in this email including any attachments may be privileged orconfidential and is intended exclusively for the addressee. The viewsexpressed may not be official policy, but the personal views of the originator.If you have received this email in error, please notify the sender by return emailand delete it from your system. You should not reproduce, distribute,store, retransmit, use or disclose its contents to anyone. Please note wereserve the right to monitor all e-mail communication through our internaland external networks. Turner and the Turner marks are trade marks ofTurner Broadcasting System Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No. 1927955), TurnerEntertainment Networks International Limited (Company No. 2803512),Turner Broadcasting System Holdings (Europe) Limited (Company Number2802926) and Cable News International Limited (Company No. 5001368) areincorporated in England and Wales and share the same registered office atTurner House, 16 Great Marlborough Street, London WlF 7HS.Information in this email including any attachments may be privileged orconfidential and is intended exclusively for the addressee. The views expressed maynot be official policy, but the personal views of the originator. If you have receivedthis email in error, please notify the sender by return e-mail and delete it from yoursystem. You should not reproduce, distribute , store, retransmit, use or disclose itscontents to anyone. Please note we reserve the right to monitor all e-mailNIH-002060communication through our internal and external networks. Turner and the Turnermarks are trade marks of Turner Broadca sting System Inc and are used underlicence.Turner Broadcasting System Europe Limited (Company No. 1927955), TurnerEntertainment Networks International Limited (Company No. 2803512), TurnerBroadca sting System Holding s (Europe) Limited (Company Number 2802926) andCable News International Limited (Company No. 5001368) are incorporated inEngland and Wales and share the same registered office at Turner House, 16 GreatMarlborough Street, London W 1 F 7HS.From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Sun, 9 Feb 2020 13:05:06 +0000To: Kaplan, Edward HCc: Redfield, Robert R. (CDC/OD);Cetron, Marty(CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD)Subject: RE: Coronavirus containment modelingAttachment s: hems_ Wuhan_Feb7 _2020_1n_Press.pdfEd:Many thanks for sendjng the manuscript . I hope that all is well with you.Best regards,Tony-----Original Message------------~~ From: Kaplan , Edward H (b) (6)>Sent: Saturday , February 8, 2020 I 0: 13- -PM-- --~~ To: Fauci , Anthony (NTH/NlAID) [E] (b)(6) >Subject: Coronavirus containment modeLingDear Dr. Fauci,It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI.The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation andquarantine might interest you. The news is mostly good - isolation and quarantine can ge1 the transmission ratebelow epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas foralleviating congestion in the hospital. I hope that you find it helpful.Best, Ed KaplanEdward H. Kaplan, Ph.D.William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor ofEngineering Yale School of Management Box 208200 New Haven, Conne cticut 06520-8 200Phone: (b)(6)e-mai l: _______ C_b)_C_6 )http://faculty.som.yale.edu/EdKaplan/NIH-002061From:Sent :To:Subject:Fauci, Anthony (NIH/NIAID) [E)Sun, 9 Feb 2020 12:40:23 +0000Conrad, Patricia (NIH/NIAID) [ElRE: CNNI Interview Request: Dr. Anthony Fauci,I will do this and if they can bring a truck to the house like they did last time, it was great. Letus discuss.From: Hynds, Joanna (NE) <Joanna.Hynds@turner.com>Sent: Sunday, February 9, 2020 6:06 AM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)Cc: Tejera, Isabel (Intern) <isabel.Tejera@turner.com>; Lovejoy, Hannah (NE)<Hannah.Lovejoy@turner.com>Subject: CNNI Interview Request: Dr. Anthony Fauci,Dear Dr Fauci,I hope you are well! I am reaching out from CNN International to enquire if you are available today tojoin us on Connect the World at llaET to discuss the coronav irus.Migh t this be a possibility? It would be great to arrange this.Background on CNN• CNN International reaches more than 250 million households worldwide including in the US viaDIRECTV.• CNN International is the number one internat ional TV news channel according to all majormedia surveys across Europe, the Middle East and Africa, the Asia Pacific region and LatinAmerica.• In September 2019 CNN.com had 162 million unique readers globally per month and 114 millionmobile readers a month, leading the BBC, Yahoo and New York Times.Best,Joanna HyndsPlanning DeskCNN International+ 44 207 693 1640 (office)+ (b)(6) {cell)joanna.hynds@turner .com■ go thereNIH-002062NIH-002063Information in this email including any attachments may be privileged or confidential and is intendedexclusively for the addressee. The views expressed may not be official policy, but the personal views ofthe originator. If you have received this email in error, please notify the sender by return e-mail anddelete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose itscontents to anyone. Please note we reserve the right to monitor all e-mail communication through ourinternal and external networks. Turner and the Turner marks are trade marks of Turner BroadcastingSystem Inc and are used under licence.Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment NetworksInternationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited(Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) areincorpo rated in England and Wales and share the same registered office at Turner House, 16 GreatMarlborough Street, London WlF 7HS.From:Sent :To:(b)(6)Sun, 9 Feb 2020 07:08: 49 -0500Conrad, Patricia (NIH/NIAID) [E)Subject: Fwd: CNNI Interview Request: Or. Anthony Fauci,Sent from my iPhoneBegin forwarded message:From: "Hynds, Joanna (NE)" <Joanna.Hynds@tumer.com>Dat e: February 9, 2020 at 6:06:15 AM ES-T-- ---~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH >Cc: "Tejera, Isabel (Intern)" <isabel.Tejera@turner.com >, "Lovejoy , Hannah (NE)"<Hannah.Lovejoy @turner.com>Subject: CNNI Interview Request: Dr. Anthony Fauci,Dear Dr Fauci,I hope you are well ! I am reaching out from CNN International to enqui re if you areavailable today to join us on Connect the World at ll aET to discuss the coronavirus.Might this be a possibility? It would be great to arrange this.Background on CNNBest,• CNN International reaches more than 250 million households wor ldwide includingin the US via DIRECTV.• CNN International is the number one international TV news channel according toall major media surveys across Europe, the Middle East and Afr ica, the Asia Pacificregion and Latin America .• In September 2019 CNN.com had 162 million unique readers globally per monthand 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New YorkTimes.Joanna HyndsPlanning DeskCNN International+ 44 207 693 1640 (office)+ (b)(6) ( cell)NIH-002064NIH-002065joan na. hynds@turner.com mmgo t hereInformation in this email including any attachments may be privileged orconfidential and is intended exclusively for the addressee. The views expressed maynot be official policy , but the personal views of the originator. If you have receivedthis email in en-or, please notify the sender by return e-mail and delete it from yoursystem. You should not reproduce, distribute, store, retransmit, use or disclose itscontents to anyone. Please note we reserve the right to monitor all e-mailcommunication through our internal and external networks. Turner and the Turnermarks are trade marks of Tmner Broadcasting System Inc and are used underlicence.Turner Broadcasting System Europe Limited (Company No. 1927955), TurnerEntertainment Networks International Limited (Company No. 2803512) , TmnerBroadcasting System Holdings (Europe) Limited (Company Number 2802926) andCable News International Limited (Company No. 5001368) are incorporated inEngland and Wales and share the same registered office at Turner House, 16 GreatMarlborough Street, London WlF 7HS.From:Sent:To:Subject :Janee:Fauci, Anthony (NIH/NIAID) [E)Sun, 9 Feb 2020 03:33:50 +0000Janet TobiasRE: Background questionNothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although therehave been specu lation that because there is about 80-90% homology between nCo V and SARS that there may besome use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera frompatients with nCoV and checked if it neutralized SARS and vice versa.Best,Tony-----Original Message-----From: Janet Tobias <janet@ikanamed ia.com>Sent: Sanrrday,F ebruary 8, 2020 6:27 -P-M- -----=,-,--:= To: Fauci, Anthony (NIH/NIAID) [E] ______ C>b<_·Subject: Background questionDear Tony: I have a background question as I am wading through reading as much as possible on the 2019coronavirus. Do we know if the antibodies 1hat can neutralize SARS are also effective against the 2019 corona virus?] may be complete ly off track, but just liying to think through some things l am reading.JanetSent from my iPhoneNIH-002066From:Sent :To:Subject:Fauci, Anthony (NIH/NIAID) [E)Sun, 9 Feb 2020 03:28:39 +0000Lenardo, Michael (NIH/NIAID) [E]RE: Hope you're doing well.Thanks, Mike. Am hanging in there.From: Lenardo, Michael (NIH/NIAID) [E]- -------- (b) ~ > Se nt: Saturday, February 8, 2020 5:18 PMTo: Fauci, Anthony (NIH/NIAID) [E] -------=- (b)c-(c= >Subject: Hope you're doing well.Hi Tony,Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sureyou're busy with the coronav irus crisis.You continue to be my inspiration!Best wishes, MikeMichael Lenardo M.D.NIH Distinguished InvestigatorChief, Molecular Development of the Immune System SectionLaboratory of Immune System Biology,Director, Clinical Genomics Program,Nationa l Institute of Allergy and Infectious DiseasesNationa l Institutes of HealthBuilding 10, Room 11D1410 Center Drive, MSC 1892Bethesda, MD 20892-1892 USATel: (b)(6) (O); (b)(6)(M)FAX: 301-402-8530Email: (b)(6) ------ASSISTANT: Gloria RodelaTel: (b)(6)Email (b)(6)NIH-002067From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Sat, 8 Feb 2020 20:54:52 +0000(b)(6)Subject:Attachments :FW: Invitenejmoa2001316.pdfHere it is. As discussed, let us re-read and convene sometime tomorrow tooutline our approach.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone Cb()6 )FAX : (301 496-4409E-mail : Cb()6 )The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Baden, Lindsey, M.D.<lbaden@nejm.org>Sent: Saturday, February 8, 2020 12:51 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( >Subject: InviteTony,As I am sure you are aware we recently web released the attached paper providing some initialestimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out ina print issue and we would like an editorial to go with it. Might you be w illing/interested in authoringsuch a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as youprovide it to us we will web release it and then link it with the attached article in an upcoming printissue. Are you interested?Please confirm no potential COis.Thank you for considering,LindseyLindsey R. Baden, MDDeputy EditorNew England Journal of MedicineNIH-002068NIH-002069This email message is a private communication. The information transmitted, including attachments , isintended only for the person or entity to which it is addressed and may contain confidential, privileged,and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, ortaking of any action in reliance upon, this information by persons or entities other than the intendedrecipient is unauthorized by the sender and is prohibited. If you have received this message in error,please contact the sender immediately by return email and delete the original message from allcomputer systems. Thank you.From:Sent :To:Cc:Subject:Sae:Fauci, Anthony (NIH/NIAIO) [E)Sat, 8 Feb 2020 17:44:45 +0000Robinson, Sae;Conrad, Patricia (NIH/NIAID) [Elnaugenstein@wtop.comRE: request for info from WTOP's Neal AugensteinI assume that this is taken care of with the interview that I just gave fo r WTOP todayThanks,TonyFrom: Robinson, Sae <srobinson@wtop.com>Sent : Saturday, February 8, 2020 7:57 AM -------~= To: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6)Subject: Re: request for info from WTOP's Neal AugensteinWe will call at 11:20 am. Thank you both!On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El- -------- (b)(6)> wrote:Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please callhim at (b)(6) back up cell at (b)(6)What is the exact hit time?Sent from my iPhoneOn Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E]-------- (b)( > wrote:Sae:Patty wi ll get back to you today.Best,TonyFrom: Robinson, Sae <srobinson@wtop.com >Sent : Saturday, February 8, 2020 7:06 AM -------~~ To: Conrad, Patricia (NIH/NIAID) [EI_ _______ C>b_C_,; Fauci,NIH-002070Anthony (NIH/NIAID) [E] -------- (b)(6)Subject: Re: request for info from WTOP's Neal AugensteinGood morning.I'd like to follow up on yesterday's inquiry from our repo rter Neal.If Dr. Fauci is available to address the concerns of this cruise ship in Japanwith Corona virus (re: air circulation system) today, we'd love him to havehim on.Unfortunately, the first available interview time is after 11 a.m.If it works, please let me know. This time, we'd like to record an interview tobe used for air so we have some flexibility.Thank you !Sae RobinsonWTOP News202-895-5060On Feb 7, 2020, at 12:59, Augenstein, Neal<naugenstein@wtop .com> wroteBegin forwarded message:From: "Conrad, Patricia (NIH/NIAID) [E]"(b)( >Date : February 7, 2020 at 12:17:40 PM ESTTo: "Augenstein, Neal" <naugenstein@wtop .com>Subject: RE: request for info from WTOP's NealAugensteinDr Fauci asked that I respond - he is inback to back meeting today up untilabout 7 pm. If you want to speak withhim tomorrow-we might be able tomake that workPatricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNIH-002071National Institute of Allergy and InfectiousDiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301 -496 -4409 faxDisclaimer:The information in this e-mail and any of its attachments isconfidential and may contain sensitive information. It should notbe used by anyone who is not the original intended recipient. Ifyou have received this e-mail in error please inform the senderand delete it from your mailbox or any other storage devices.National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liabi lity for any statement made that aresender's own and not expressly made on behalf of the NIAID byone of its representatives.From: Augenstein, Neal<naugenstein@wtop .com>Sent: Friday, February 7, 2020 8:29 AMTo: Fauci, Anthony (NIH/NIAID) [E](b) (6)>Subject: request for info from WTOP's NealAugensteinHi, Dr. Fauci. Hope you're wellSpokew ith some passengersa board the DiamondPrincess cruise ship in Japan, where the number ofcoronavirus cases onboard are jumping. Can we doa brief interview re: thoughts on quarantining onboard ship (with, I would assume a closedcirculating air system) versus evacuating them?I'm available at your earliest convenience. Or, ifyou'd like to just email some thoughts, that'd begreat. Thanks and best.NIH-002072Neal AugensteinReporter103.SFM and wtop.comWashington, DC(b)(6) cell202-895-5060 newsroomnaugenstein@wtop.comTwitter: @AugensteinWTOPSkype: WTOPNealAugensteinNIH-002073From:Sent:To:Cc:Fauci, Anthony (NIH/NIAIO) [E)Sat, 8 Feb 2020 17:30:45 +0000Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [ElNIAID ODAMSubject :desktop?RE: David ·• how do we put a link to the Coronavirus public folder on ASF'Monday is fine .From: Awwad, David (NIH/NIAID) [C) --------- (b)( >Sent: Saturday, February 8, 2020 12:11 PMTo: Folkers, Greg (NIH/NIAID) [E]--------=- (b")("=6")>Cc: NIAID OD AM <NIAIDODAM@niaid .nih.gov>Subject : Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop?I will add Monday, unless you want me to connect now.Sent from my iPhoneOn Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [Elwrote:<image0Ol. jpg>(b)(6)Disclaimer: Any third-part y material iu this email has been shared for internal use under fairuse provisions of U.S. copyright law, without further verification of its accuracy/veracity. Ltdoes not necessa rily repr esent my views nor those of NIA ID, NIH, HHS, or the U.S.goverumeut.NIH-002074From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sat, 8 Feb 2020 17:29:51 +0000To: Conrad, Patricia (NIH/NIAID) [E)Subject: FW: Fox and Friends video -- US confirms first American coronavirus death/ ASFauci http;/ /bit.ly /2tltgneFyi. It came out well.From: Folkers, Greg {NIH/N IAID) [E) (b)(6)Se nt: Saturday, February 8, 2020 11:34 AMSubject: Fox and Friends video -- US confirms first American coronav irus death/ AS Faucihttp://bit .ly/2tltgneDisclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisionsof U.S. copyrig ht law, without further verification of its accuracy/veracity . It docs not necessarily repre sentmy views nor those of NlAlD, NIH, HHS, or the U.S. government.NIH-002075From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAID) [E)Sat, 8 Feb 2020 17 :24 :25 +0000Conrad, Patricia (NIH/NIAID) [E)Barasch, Kimberly (NIH/NIAID) [C)RE: CNN Interview Request: Dr. Anthony FauciI believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We mayalso be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that this istaped. I leave this up to you and so please get back to them and work it out if you can. JimSciutto CbH6)), Thanks.From: Griffin, Janelle <Janelle.Griffin@turner.com>Sent : Saturday, February 8, 2020 11:33 AM -------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)Subject: CNN Interview Request: Dr. Anthony FauciImportance: HighGood mornin g Dr. Fauci ,I hop e this email finds you doing well.I'm reaching ou t on behalf of Newsroom w/Popp y Harlow & Jim Sciutto hop ing you can join for aninterview.Are you available to join CNN this Monday February l 0th in the 1 Oa et hour?This would be live for about 5-7 minutes to discuss developments regarding the coronavirus.Please feel free to contact me via email or at ------Cb)( 6) to let me know.Thanks for your time- I look forward to hearing from you soon.Janelle Griffin-ButtsEditorial Producer, CNNEmail: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN NNIH-002076From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sat, 8 Feb 2020 03:23:51 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ETI am OK with their coming to the house without a truck. I will call you in the AM.From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)>Sent: Friday, February 7, 2020 7:42 PMTo: Fauci, Anthony (NIH/NIAID) [E]--------=- (b'")("=6' )>Subject: Fwd: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ETAm at din ner. Will call u laterSent from my iPhoneBegin forwarded message:From: "Zuccaro, Alexandra" <Alexandra.Zuccaro@FOXNEWS.COM>Date : February 7, 2020 at 7:16:21 PM EST -------~= To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ETThey'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too!From: Conrad, Patricia (NIH/NIAID) [E) ----------- (b)(6) Sent: Friday, February 7, 2020 6:51 PMTo: Zuccaro, Alexandra <Alexand ra.Zuccaro@FOXNEWS.COM>Subject: (EXTERNAL] Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30amETWill they set up outside his house or is this the trick that he goes into it for the interview?Sent from my iPhoneOn Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra<Alexand ra.Zuccaro@foxnews.com > wrote:Hi Everyone,NIH-002078Babu Aryankalayil is set to arrive at (b)(6)around 7:30am/est tomorrow for our interview with Dr. Anthony Fauci. Babu,please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFBand Pl Numbers are below. Please let us know if you have any questions, andplease also let us know what REM this will be on."Fox & Friends"DATE: Saturday, February 8thCREW ARRIVAL TIME: 7:30am ETADDRESS: (b)(6) -------------LIVE TALK BACK: 8:35am ET - 8:40am ET with Pete Hegseth, Emily Compagno,& Jason ChaffetzSatellite Window : 0700 -0800GUEST: Dr. Anthony FauciTOPIC: CORONAVIRUS CRUISE SHIP LATESTGUEST CONTACT: Dr. Anthony Fauci, (b)(6) / Media contact PatriciaConrad cell : (b)(6)cell :-_:..!:====:::!..: (b ~ )- (~6)CREW CONTACT: Babu Aryankalayi l, -----(b)(6)/ (b)(6)F&F NYC CONTACTS:Technical Director: Todd Boone: Phone -----(-b)(6) email: todd.boone@foxnews.comF&F Control Room Contact: Tami Radabaugh, (b)(6) email:Tami .Radabaugh@FOXNEWS.COMPl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4)IFS: 800-369-6719ACQ and REM Coordinator : 212-301-3200NY Transmission : 212-301-3100NY Sat Desk {Bookings) 212-301-3400A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYCGreenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COMThanks,Alexandra ZuccaroNIH-002079"Fox & Friends"Fox News Channel1211 Avenue of the Americas, 2nd FloorNew York, NY 10036Cell : (b)(6)Alexandra .Zuccaro@FOXNEWS.COMThis message and its attachments may contain legally privileged orconfidential information. It is intended solely for the named addressee .If you are not the addressee indicated in this message ( or responsible fordelivery of the message to the addressee) , you may not copy or deliverthis message or its attachments to anyone . Rather, you shouldpermanently delete this message and its attachments and kindly notifythe sender by reply e-mail. Any content of this message and itsattachments that does not relate to the official business of Fox News orFox Business must not be taken to have been sent or endorsed by eitherof them. No representation is made that this email or its attachments arewithout defect.NIH-002080From:Sent :To:Cc:Fauci, Anthony (NIH/NIAID) [E)Fri, 7 Feb 2020 20:20:58 +0000Mellors, John WSubject:Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [ClRe: Important Brief ConversationAttachments : image0Ol.gifI know. Glad we could work it outOn Feb 7, 2020, at 11: 48 AM, Mellors, John W ------ (b)(6) wrote:Dear Tony,Approva l received from DHHS. The shipment of remdesivir to China is on it's way.No need to connect.Thanks,JohnFrom: Fauci, Anthony (NIH/N IAID) [E) (b)(6)>Sent: Thursday, February 6, 2020 7:04:53 PMTo: Mellors, John W -~----(b)- ( ->- -----~~ Cc: Conrad, Patricia (NIH/N IAID) [E] (b)( ; Barasch, Kimberly{NIH/NIAID) [C] (b)(6)Subject: RE: Important Brief ConversationJohn:Please give me office a call tomorrow and they will set up a time to connect us.Best,TonyFrom: Mellors, John W (b)(6)Sent : Thursday, February 6, 2020 5:38 PM ---------------=~ To: Fauci, Anthony (NIH/N IAID) [El (b)(6)·_...:._ _ :....:.,..:.~-------------- Cc: Mellors, John W (b)(6)>Subject: Importan t Brief ConversationDear To ny , CliffCould we speak briefly about an important interna tio nal coronavirus trial that is injeopardy?My mob ile phone number is -----(b)(6)JohnNIH-002081John W. Mellors, M.D.Chief, Division of Infectious DiseasesDistinguished Professor and Endowed Chair for Elimination of HIV and AIDSUniversity of Pittsburgh Schoo l of Medic ineScaife Hall , Suite 8183550 Terrace StreetPittsburgh, PA 15261Tel : (b)(6)Fax: 412 383-7982E-mail: (b)(6)Visit our Division website: http://www.dept-med.pitt.edu/lD/Read the "ID Pitt Stop" blog: https://idpittstop.wordpress.comLike us<image00 1. gif>NIH-002082From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 15:37:53 +0000(b)(6)Subject: RE: NIH posit ion on travel to Singapore???Go to CDC we bsite. There are no t rave l alerts fo r Singapore and so f or now it isOK to trave l t here.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: (b)(6) ----------------- Sent : Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E]-- -------------=(b~)(6)> Subject: Fwd: NIH position on travel to Singapore???jim lynch is asking for sources of info for travel advice re: coronavirus . ___ C_b><6) is planning to go toSingapore . any suggestions?---------- Forwarded message ---------From: James L (b)(6)>Date : Thu, Feb 6, 2020 at 8:16 AMSubject: NIH position on travel to Singapore???To: 00~Hi (b)(6)------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week .What is the best source of up-to -date information and travel recommendations related to thecoronavirus?ThanksNIH-002083Jim(b)(6)NIH-002084From:Sent:To:Subject :Let us discus.Fauci, Anthony (NIH/NIAID) [E)Fri, 7 Feb 2020 10:46:54 +0000NIAIDODAMFW: Royal Society of Medicine london-----Original Message -----From: Ian Hosein _________ ("b,a)"(=S "'"Sent: Friday, February 7, 2020 5:20 A-M- ----~~= To: Fauci, Anthony (NIH/NIAID) [E].___ ____ C>b<.. ..Subject: Royal Society of Medicine londonHello Dr Fauci,By way of introduction , 1 was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since thenas a medi cal microbio logist and hospital epidemio logist.J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about youravailabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November24th coming?The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The programis still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I canapply to cover your trip but will need to do so soon.Jt was both exciting and inspirational being a senior staff fellow at the Nll-1 - my background is international;--,------------,---,-,,-----,-....,...,.,...-----,,--,-,---(b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH forthe US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought thespirit of that institution to other nations.With kind regards ,lanlan K Hosein MD FCAP FRCPath MBARoyal Society of MedicineLondonMobi le--- (~b)~(6=)Sent from my iPadNIH-002085From:Sent :To:Subject:Attachment s:Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:56:15 +0000Conrad, Patricia (NIH/NIAID) [ElFW: Comment on NEJM details of "asymptomat ic" contact in Germanynejmc2001468_appendix.pdfPlease set up a call. Happy to do over the weekend or Friday evening.From: Ian Ingram <iingram@medpagetoday.com>Sent : Thursday, February 6, 2020 1:34 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)( >Subject: Comment on NEJM details of "asymptomatic " contact in GermanyHi Or. Fauci,I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPageToday, but I wanted to see if you could were available to offer your quick reaction to the Supplement aryIndex publ ished today (attached) in the New England Journal of Medicine regarding the widely reportedasymptomati c contact in Germany.Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies assymptomatic or not . I imagine this will be disputed.Best regards,- IanIan IngramDeputy Managing Edi torMedPage Today LLC(b)(6)iingram@medpagetoday.commedpagetoday. comNIH-002086From:Sent :To:Cc:Subject :Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:53:47 +0000Conrad, Patricia (NIH/NIAID) [E)Barasch, Kimberly (NIH/NIAID) [C)FW: BuzzFeed News; 2019-nCoV vaccine development questionsPlease set up a call with this person. Happy to do over the weekend.From: Dan Vergano <dan.vergano@buzzfeed .com>Sent : Wednesday, February 5, 2020 3:18 PM ------- ~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6)Subject : BuzzFeed News: 2019-nCoV vaccine development questionsDr. Fauci,As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have anyperspective (or might recommend someone to commen t) for a novel coronavirus story we are writingfor this weekend, regarding vaccine efforts .In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDChas described the virus as not mutating as much as influenza -- does that suggest a vaccine wouldprovide more than seasonal protection?In the long te rm, we had a few other questions. Is this something you could see added to the MMRprotoco l for the general public, or only in regions where there are local outbreaks (is there an analogy toSARS or MERS vaccines in this contemplated use)? Is the re any aspect of a race against time in vaccinedevelopment if this coronavirus is seasonal like influenz a?We are basically trying to understand where a vaccine fits into the future response to this new virus. weasked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot.Apologies for all the quest ions, if you had any perspective, we'd be gratefulDan VerganoBuzzFeed News(b)(6)cc: Kathy StoverDan Verg ano I Science Desk (DC) IBuzzFeed News-----(b)(6)1630 Connecticut Ave. 7th Floor, Washington DC 20009Send secure tips -- cont act .buzzfeed.comNIH-002089From:Sent :To:Subject :Very interesting! !Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:45:34 +0000Folkers, Greg (NIH/NIAID) [E]RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan casesFrom: Folkers, Greg (NIH/NIAID) [E] (b)(6)>Sent: Thursday, February 6, 2020 2:22 PMTo: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c=Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El(b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea":'---:----:-~===:::.;..--~~(NIH/NIAID) (E] (b)(6)]; Marston , Hilary (NIH/ NIAID) (El (b)(6)Subject : ASF / please see table from 1-29-20 19 NEJM paper on Wuhan casesPlease see next to last line, wh ich gives% of transmissions with "no exposure to either marketor person with respiratory symptoms"(b) (5)N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print]Early Transmission Dynamics in Wuhan, China,of Novel Coronavirus-lnfected Pneumonia.Li Q1, Guan x1, Wu P1, Wang x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1,Xiang N1, Wu Y1, Li C1, Chen Q1, Li D1, Liu r 1, Zhao J1, Li M1, Tu W1, Chen c1, Jin L1, Yang R1, Wang Q1,Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 81, Ma z1, Zhang Y1,Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowling BJ1, Yang B1, Leung GM1, Feng z1.DOl:10.1056/NEJMoa2001316NIH-002090NIH-002091e(r 11:&e)-y_ - no./cow no. (")els yr1S yr'1S-64 r65 ~'e , - no./tot no. (%)posure 15 OI)'- no./tot I no. (")We1 ma et posurHu II n Seafood Wholewle M ,kcOther muk b-ul not Hu1n•n S 1foodH C n:c-1ConHe,I c~rl' wor c-r - no /tot1I no , ('(,)lklore January l January l 1 an11 r,r 11(N• 471 [ - u•1S6 (26--32) 60(21 9)0/47 0/24312/◄ 7 (26) 39[24 (16)24/47 (5 ) 06/24 (0)11/47 (23) 03/:J.48 (42)31/47 (66) 147/24 (59)J0/O (641 12/196116)26/47 (5S) 19/196 (10)"''' (9)U/196 (7)Hi/47(30 30/196 (15)12f47 (26) 141(196 {72)0/1.7Rc,duc~ denom1na ors 1ndic le m1ssin da t P ccMu es m1r no to 100 b« use o round nJanLE&l'Yl2 -:I u 22(N• llO)6 ( S.-89)OJlJOH/130(25)49/lJO(lSJ&/ 30 (37)62/ 30 (48)s (6)5/81 (6)0/8121/83 (25)59/81 (73)a,m (1)Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily representmy views nor those ofNIAID , NIH , HHS, or the U.S. government.From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:38:45 +0000Conrad, Patricia (NIH/NIAID) [E)Barasch, Kimberly (NIH/NIAID) [C)FW: LatestPlease set up a call with David for the weekend.From: davidwillman (b)(6)Sent : Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)-_ -_-_-_-_-_~_ ~ CbH_6)Subject: LatestHi Tony,I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like toconfer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'llalso call Kim Barasch, per your recent guidance.I'm researching an article that will chiefly explore the status of the Defense Department's advanceddevelopment and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re thethree HHS/BARDA facilities.Best, DavidDavid WillmanWashington Post202-334-7081-desk----C-b)-( 6) -mobile 301-656-3401 --alternate deskdavid.willman@washpost .com(b)(6)NIH-002092From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:11: 47 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: FW: Reporter working on coronavirus vaccine storyLet us discuss. Maybe over the weekendFrom: Morris , Amanda <Amanda.Morris@gannett.com>Se nt: Thursday, February 6, 2020 4:11 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b')"("=6')Subject: Reporter working on coronavirus vaccine storyHi Anthony,I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the ArizonaRepublic, part of the USA Today network. I'm reaching out because I'm currently working on a storyabout how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to developstrategies to make a vaccine against the new coronav irus as well as a general platform they can use inthe case of future new coronavirus strain outbreaks in humans.I know globally there are many researchers trying to develop a vaccine for this new coronavirus, andthat the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'mwondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing,and what the broader challenges are for developing a vaccine? I'd like to have broader context aboutvaccines for our readers.Please let me know as soon as possible. You can call or text me at -----(b)(6) Thank you!All my best,Amanda Mo r risBioscience Reporter for The Arizona RepublicWork phone: 602-444-8739After hours and weekends, you can call or text my cell: __ (_b)_(6_J.Email : amor ris@gannett .comNIH-002095From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:04:53 +0000Mellors, John WCc:Subject :Conrad, Patricia (NIH/NIAID) [E);Barasch,K imberly (NIH/NIAID) [CJRE: Important Brief ConversationJohn:Please give me office a call tomorrow and they will set up a time to connect us.Best,TonyFrom: Mellors, John W (b) (6)Sent: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,A nthony (NIH./:.N. _IA_ID..):...[.E:._~).; ~------------ (b_)(6)Cc: Mellors, John W (b)(6)Subject : Important Brief ConversationDear Tony, CliffCould we speak briefly about an importan t international coronavirus trial that is in jeopar dy?My mobile phone number is -----(b)(6)JohnJohn W. Mellors, M.D.Chief, Division of Infectious DiseasesDistinguished Professor and Endowed Chair for Elimination of HIV and AIDSUniver sity of Pittsburgh School of MedicineScaife Hall, Suite 8183550 Terrace StreetPittsburgh , PA 15261Tel: CbH6)Fax: 412 383-7982E-mail Cb()6 )lVisit our Division website: http ://www.dept-me d.pitt.edu/ lD/Read the "ID Pitt Stop" blog: https://idpittstop.wor dpress .comLike us (INIH-002096From:Sent :To:Subject:Howard:Fauci, Anthony (NIH/NIAI0) [E)Fri, 7 Feb 2020 03:01:07 +0000Howard BauchnerRE: Subtitled Coronavirus VideoThanks for the feedback.Best,TonyFrom: Howard Bauchner <Howard.Bauchner@jamanetwork.org>Sent: Thursday, February 6, 2020 6:39 PM ------ --.~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J>Subject: FW: Subtitled Coronavirus VideoTonyFirst live stream/podcast now with Chinese interpretation. URL below.Second live stream/podcast will be put up tomorrow. URL below .Couple big thank yous from prominent science writers - NYT /WSJ - said learned more listening to youfor 30 minutes then everything they read in the last few weeks.My response when you have a very wise scientist, who hears the question and answers the question,and has 40+ years of experience we should listen and learn.Be well.HCBHoward Bauchner, MDEditor in Chief of JAMA and the JAMA Netwo rkPlease respect the confidentiality of t his emaillisten to my chats with author sFrom: Karen Adams- Taylor <Karen.Adams-Taylor@ama-assn .org>Date : Thursday, February 6, 2020 at 4:59 PMTo: Howard Bauchner <Howard .Bauchner@ jamanetwork.org >, Annette Flanagin<Annette .Flanag in@jamanetwork.o rg>, Michae l Berkwits<Michael.Berkwits@jamanetwo rk.org>, Tom Easley <Tom .Easley@ama-assn.org >, Brian Shields<Brian.Shields@ama -assn.o rg>, Betsy Solaro <Elizabeth .Solaro@ama -assn.o rg>, Sean O'DonnellNIH-002097<Sean. O' Donnel l@a ma-assn. org>, Tiffany Jones <Tiffany .J ones@a ma-assn.erg>Subject : Subtitled Coronav irus VideoThe 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alertThe 2/6 Fauci update video will go to the trans lator tomorrow.-KarenKaren Adams-TaylorVice President, Publishing Production OperationsJAMA Network ™330 N Wabash Ave, Ste 39300, Chicago, IL 60611T -----(b)(6) jamanetwork.comNIH-002098From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Fri, 7 Feb 2020 03:00:35 +0000To: Greg Folkers (b)(6) ;Billet , Courtney (NIH/NIAID) [E];Routh,Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [ElSubject: FW: Subtitled Coronavirus VideofyiFrom: Howard Bauchner <Howard .Bauchner@jamanetwork.org>Se nt: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El (b)( >Subject: FW: Subti tled Coronavirus VideoTonyFirst live stream/podcast now with Chinese interpretation . URL below.Second live stream/podcast will be put up tomorrow . URL below.Couple big thank yous from prominent science writers - NYT /WSJ - said learned more listening to youfor 30 minutes then everything they read in the last few weeks.My response when you have a very wise scientist, who hears the question and answers the quest ion,and has 40+ years of experience we should listen and learn.Be well.HCBHoward Bauchner, MDEdito r in Chief of JAMA and the JAMA NetworkPlease respect the confidentiality of this emailListen to my chats with authorsFrom: Karen Adams-Tay lor <Karen.Adams -Taylor@ama -assn.org>Date: Thursday, February 6, 2020 at 4:59 PMTo: Howard Bauchner <Howa rd.Bauchner@jamanetwork .org>, Annette Flanagin<Annette .Flanagin@jamanetwork.org >, Michae l Berkwits<Michael.Berkw its@jamanetwork.org >, Tom Easley <Tom.Easley@ama -assn.org >, Brian Shields<Brian.Shields@ama-assn.org >, Betsy Solaro <Elizabeth .Solaro@ama -assn.org >, Sean O'Donnell<Sean.O'Donne ll @ama-assn.org>, Tiffany Jones <Tiffany.Jones@ama-assn .org>Subje ct: Subtitled Coronav irus VideoNIH-002099The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalertThe 2/6 Fauci update video will go to the trans lator tomorrow.-KarenKaren Adam s-TaylorVice President, Publishing Production OperationsJAMA Network rM330 N Wabash Ave, Ste 39300, Chicago, IL 60611T -----(b)(6) jamanetwork.comNIH-002100From: (b)(6)Sent: Thu, 6 Feb 202015:09:43 -0500To: Folkers, Greg (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea(NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E]Subject: Re: ASF --- Morens + Daszak +Taubeneberger paperI agree. I will not be a co-authorOn Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E]----------- CbH wrote:So the question to you - do you want to be part of this? ie be acoauthor(b) (4)I would vote no - it wud look weird to add you as a coauthor now. Plus,plate too full. .....Disclaimer: Any third-party material in this email has been shared for internal use under fairuse provisions of U.S. copyright law, without further verification of its accuracy/veracity. Itdoes not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S.governme nt.NIH-002104From:Sent:To:Cc:Subject:Thanks, Jim.Anthony S. Fauci , MDDirectorFauci, Anthony {NIH/NIAID) [E]Thu, 6 Feb 2020 17:36:11 +0000(b)(6)(b)(6)RE: nCoV: Heads-upNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX : (301 496-4409E-mai l (b)(The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: (b)(6) ------------------- Sent: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) -------------- --(b~)(6) Cc: (b) (6)Subject: nCoV: Heads-up. We will keep you updated. Best. John and JimFrench drugmaker Sanofi workin g on coronavirus initiativeCHINA-HEALTH/SANOFI (PIX):French drugmaker Sanofi working on coronavirusinitiativePARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiativewithin the next two weeks, its chief executive said on Thursday, adding that it wants to presentsomething concrete and not add to "fantasies".At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with thefast-spreading virus that has killed more than 500 people in China, but several have warned thatdevelopment of treatments will take time.NIH-002105NIH-002106"We have seen a flurry of activities from other companies," CEO Paul Hudson told a newsconference after Sanofi published 2019 results on Thursday."We are one of the few companies that has the expe1iise to know when it is just a fantasy, orwhen it could be real. In the next week or two, you will see something more confinnatory aboutthe approach we will take."Hudson declined to give further details.Sanofi had already said it was sharing its expertise and data acquired from other outbreaks withthe Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotechbusinesses to try to develop a vaccine candidate for the coronavirus.Britain's GlaxoSmithKline is also collaborating with CEPI."The objective here is not a newspaper headline, it is real work that will make a difference ,"Hudson said.(Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman)From:Sent:To:Cc:Subject:Attachments:Fred:Fauci, Anthony (NIH/NIAIO) [E)Thu, 6 Feb 2020 16:28:04 +0000h iattf@washpost.comRedfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E]Proposed OpEdRedfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docxI hope that all is well with you . (b)(6)-------------------- (bH6J. Within this context, Bob Redfield and I have written an OpEd on the government response to the novel coronavirusoutbreak. Would the Post have any interest in this? Many thanks.Best regards ,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not express ly made onbehalf of the NIAID by one of its representatives .NIH-002107From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Thu, 6 Feb 2020 14:34:57 +0000To: Billet, Courtney (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary(NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E]Subject: RE: Requested coronavirus talking points for press conferenceAttachments : Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 -Fauci Press remarks with tracked edits.docxOooops! Forgot the attachment. Here it is.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave rece ived this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From : Fauci, Anthony (NIH/NIAID) [E]Sent: Thursday, February 6, 2020 9:34 AM ------~= To: Billet, Courtney (NIH/NIAID) [E) (b)(6)Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E](b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer"(: N"":"l.'H."".-/'::N":"-.I"A'."l'D"':.")': :-[:~E:]-====-.:--_.;.. (bc)(-=c ; Stover, Kathy ( NI H/NIAI D) [E] (b)( >Subject: RE: Requested coronav irus talking points for press conferenceHere is my revised and updated press remarks with my tracked edits showing.Please accept edits, do a spell and grammar check and resubmit. Also, put a copyin my fol der . Thanks.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone : (b)(6)NIH-002114FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [El (b)(6)Sent: Thursday, February 6, 2020 9:16 AMTo: Fauci, Anthony (NIH/NIAID) [E]------= (b')"("=6)>Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)1>; Folkers, Greg (NIH/NIAID) [E](b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer"(: N"":"1.:H"-:/7'-N".I"A'.'"l"-D'':::)': --:[~E:l-===~--~ (b")"(",6=' ),;; Stover, Kathy ( NI H/NIAI D) [El (b)(6)Subject: FW: Requested coronavirus talking points for press conferenceHHS has asked us for your talking points fo r the press conference by 11am. We were planning toresubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of whatyou would say. This is not a script.Is it OK for us to send th is to Bill?From: Selgrade, Sara (NIH/NIAID) [El (b)( >Sent: Thursday, February 6, 2020 8:37 AMTo: Fauci, Anthony (NIH/NIAID) [E] _____ "("b")'"("=6)Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E](b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg(NIH/NIAID) [El (b)(6)Subject: Requested coronavirus talking points for press conferenceDr. Fauci,Attached please find the requested talking points from your last coronavirus press conference.Please let us know if you need anything else .Thanks,SaraNIH-002115From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Thu, 6 Feb 2020 10:58:13 +0000To: Collins, Francis (NIH/OD) [ElCc: Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conrad,Patricia {NIH/NIAID) [ElSubject: RE: Follow up on Addis MeetingFrancis:Thanks for the note . Best to have Trevor have his program person who will be leading thiseffort contact Cristina Cassetti in DMID. Cristina and Emily Erbelding could do all of thenecessary and approp riate coordination .Thanks,TonyFrom: Coll ins, Francis (NIH/OD) [El -------- (b)(6) Sent: Thur sday, February 6, 2020 4:56 AM -------=-,--=" To: Fauci, Anthony {NIH/NIAID) [El --------(b)(6) Subject: FW: Follow up on Addis MeetingSee reference to coronav irus research in the note from Trevor. How would you like tocoordinate this?FCFrom: Trevor Mundel (b)(6)> _____________ ..,Sent : Wed nesday, February 5, 2020 10:55 PMTo: Collins, Francis (NIH/OD) [ElCc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- (b,H;,;;6; ;J;;--G: :-la:-s"s, Roger {NIH/FIC) [El(b)(6)Kedest Tesfagiorgis (b)(6)>Subject: Re: Follow up on Add is Meeting(b)(6);That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirusreponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so wemight want a quick call in the next few days to thin k about how we coordinat e this - I've been in touchwith Jeremy as we ll. TrevorTrevor Mu ndel, MD, PhDPresident , Global Health ProgramV (b)(F +1.206 .494 .7041E (b)((ij -------------(b)(6)Execut ive AssistantOffice of the President, Global HealthNIH-002118(b)(6)(b)(6)Bill & Melinda Gates Foundationwww .gatesfounda tion.org(b)(6)From: Collins, Francis (NIH/OD) [El (b)(6)>Sent : Wednesday, February 5, 2020 3:11 PMTo: Trevor MundelCc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [ElSubject: RE: Follow up on Addis MeetingHey Trevor,This is an excellent development. How about I send you a proposal of possible CARI TPs forElioda - in the next 24 hours?Franc isFrom: Trevor Mundel (b)(6)Sent : Wednesday, February 5, 2020 4:43 PMTo: Tumwesigye Elioda CbH6l>; Collins, Francis (NIH/OD) [El -------- (b) ( >Cc: (b)(6)Subject: Re: Follow up on Addis MeetingThat's great to hear Elioda and congratulations, many thanks for letting us know . We will certain ly getback to you shortly to enlist your help with the CARI initiative at AU level.Warm regards,TrevorFrom: Tumwesigye Elioda (b)( >Sent : Wednesday, February 5, 2020 1:16 PMTo: Trevor Mundel; Francis CollinsCc: (b)(6)Subject: Follow up on Addis MeetingDear Trevor,Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meetingin Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARIInitiative and the need to support research, entrepreneurship and innovation in a big way in Africa. Wealso explored the mechanism for CARI Funding. We were also looking for a mechanism to reach theCommittee of Ten (ClO) Heads of State and Government championing Education, Science andTechnology in Africa.NIH-002119Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers ofEducation and of Science and Technology in all the 55 Members States in Africa. We do this under theSpecialized Technical Committee on Education, Science and Technology (STC-EST). This Saturday on 8thFeb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0.The purpose of this message is to let you know of my added responsibilities and related opportunities aswell as seek for any update or latest information regarding the CARI init iative . I look forward tointensified communication and collaboration.RegardsDr. Elioda TumwesigyeMinister Science, Technology and InnovationRepublic of UgandaTel: (b)(6)Sent from my iPadNIH-002120From: Fauci, Anthony (NIH/NIAID) [ElSent : Thu, 6 Feb 2020 04:10:50 +0000To: Cassetti, Cristina (NIH/N IAID) [ElCc: Conrad, Patricia (NIH/NIAID) [ElSubject: FW: PandemicThreat Reduct ionSimil ar e-Omail from Dr. Tubb.From: Richard Tubb ------- (b)(6)> Sent : Thursday, January 30, 2020 11:35 AM_To..:.. =!==~~----- C_>bC6)F auci, Ant hony (NIH/N IAID) [E](b)(6)Subject: Fwd: Pandemic Threat ReductionGood morning Tony.Given your most recent appointment , I wanted to showyou the courtesy of letting you know what I have alreadyprovided to senior leaders at the White House regarding apossible mitigating strategy until the definitive solution tothe CoV is available and implemented. The string belowincludes additional information as to how titanium dioxidecan fit into both the White House and theNational / International solutions, and the open-sourcewebsite for the company. Please keep in mind thatbecause this product is already approved and in use in theEU for a variety of commercial uses, the data provideddoes not specifically address the applications I, and you,are interested in. Ho-\iveve, rwith a deep understanding ofthe White House mission, I can say that there is not a bigleap in that thought migration.Dr. Jackson has already provided the same material tosome of your White House Commission colleagues. I willalso be reaching out to another friend of mine from theBush-now-Trump Administration, Steve Biegun.NIH-002121I encourage your representatives to meet with thecompany leadership and scientists while they are in the USnext week. Please let me know if you have any questionsthat I can address. Thank you for once again stepping upto the plate for our Country.v/rDickps .. .I remembered this morning where you and I lastspoke--Bush (41) funeral.---------- Forwarded message --------From:Richard Tubb ----------- (b) (6) > Date: Thu, Jan 30, 2020 at 8:54 AMSubject: Re: Pandemic Threat ReductionGood morning Gentlemen,I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation.First, the company's joint venture partner in India is meeting with the Indian government as we speak.It appears likely that in light of the news of India's introduction to the corona virus the government willutilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute acontract with this company.Secondly, I will attach the open source web site for the company to provide you background informationthat, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It'simportant to note a couple of things:This product is already proved and is in use in the EU with all the approvals appropriate for the same.Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues todecontamina te and disinfect in the background for up to 1-5 years before retreating. (Depending on thetype of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective thanwhat the application normally would use, e.g. in a hotel-cont inues). The chemical treats anythingorganic, I.e. bacteria, viruses, voe, bio threats, etc. because it is a catalyst, it is neither used up, norNIH-002122does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g,airplanes and government cri tical infrastructures) and the air around the surface (and HVAC fi lters andair handlers).The leadership will be in DC next week. I highly encourage any and all potential stakeholders make timeto meet with them while they are here. To that end, I had already emailed Dr. Fauci (with whom Iworked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement ofhis participat ion on the new coronavirus commission, I will also reach out to an old friend and colleagueSteve BIEGUN now that he is in the commission . Please feel free to forward the information to others asyou deem appropr iate .Thanks,Dick Tubbhtt ps://act.g lobal/Ps ... once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimesagainst the dictionary .Sent from my iPadOn Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote:Gentlemen, Brother s, and Others ...This is Dick Tubb , writing on behalf ofAdmiral Jack son and Dr. Hofmann (bothcopied herein). It feels like "old times"- -I'mundecid ed as to wheth er they are good oldtimes , or otherwise. Regardless , it does feellike we've been down a very simil ar roadbefore. Perh aps we can apply some of thelessons -learned to th e inevitable problemsahead.NIH-002123NIH-002124In light of the current and evolving threatpresented by the corona virus, I am writingto you as a courtesy to inform you of aproject that Admiral Jackson, Dr.Hofmann, and I have been consulting on.We believe so strongly in the technology,people, and potential that we have beenconsulting pro bono and currently have nofinancial stake in the project. While notdeveloped specifically designed for suchpurposes, I increasingly believe that until avaccination and treatment for the coronavirus is available, this technology may bethe last best chance in containing, anderadicating the virus, thereby protectingthe homeland, our economy, the Continuityof the Presidency, an EnduringConstitutional Government, our people andour Country. Moreover, reverting to my"lessons-learned, problems-ahead"statement, even after this crisis is over, anda vaccine and treatment procured, it willonly be a matter of time until "next time."This letter is proof-positive of that reality.My experiences, especially in the early2ooo's (e.g. anthrax and other biothreats,SARs, etc.) underpin my beliefs.The technology that provides the solution,both now and in the future, involves aunique formulation of a photo catalyticNIH-002125nano titanium dioxide solution (the AirForce guys will, of course, understand whatthat means, so you non-Air Force folks, justbuy them a beer and they'll explain it toyou) that is safer, more effective, and morecost effective than any other solution. Itwas developed and approved in the EU, andI have asked the senior leadership of thecompany to come to Washington DC nextweek. Dr. Hofmann and I spent the dayyesterday with a Chinese "titan" respectedby and with access to the most seniorgovernment officials, academic and medicalgiants, and investment and industrycaptains. I have encouraged , and he hasagreed in principal, to follow ourrecommendations as they relate to theirlargest airline, and their key facilities.In short, our strategic priority is to firstfortify the weak link in the pandemic chain:the airlines. Doing so will provide the timenecessary to isolate, contain, and ultimatelydestroy the threat at its source(Wuhan) ,and in its home (China). AsPresident Bush so commonly stated about avery different threat, we need to fight thebattle over there, so that we don't have tofight the battle here. Although PresidentBush was a true believer in the threat of apandemic, I believe this threat, and theNIH-002126threats that are surely to fallow are, inreality , many, many times greater than thethreat he envisioned when making thatstatement. By fighting a possibleimpending pandemic at its source we willpreserve and protect the safety andconfidence of our people, and the strengthof our economy.Once we have interrupted the threat supplychain, we can then shore up our criticalinfrastructure using the same technologyand process, then assist the Chinese inaddressing their challenges, and protectour international allies elsewhere . In thatvein, in addition to the Chinese, I have alsodiscussed this technology and strategy withsenior proxies for another of my formerpatients, His Royal Highness, the CrownPrince of Saudi Arabia, and his father, theKing.As I noted above , I have asked theleadership of the company to come toWashington (from Germany and Denmark)next week for a variety of meetings. WhileAdmiral Jackson will be "tied up in Texas"for the foreseeable future, please let meknow if you would like to meet with myselfor Dr. Hofmann, or the companyNIH-002127leadership while they are here, to learnmore.Thank you and my best to you all as youplan for and continue to protect ourCountry,Very Respectfully,Dick Tubbps. For your SA, I have also attached belowthe latest sit rep on the coronavirus.Richard J. Tubb, MDBrigadier General (retired)White House Physician EmeritusShoreland's Travax News Alert ServiceAbbreviatedChina: More than 2,800 Cases of 2019-nCoV in 30Provinces/Municipalities , Mainly in Wuhan ; CasesExported to 16 CountriesWHAT'S NEWAccording to regional health authorities, more than 1,800 additional ,confirmed cases (including 25 deaths) of pneumonia caused by 2019novel coronavirus (2019-nCoV) have been reported since January 27,2020, throughout the country, mainly in the provinces of Hubei (1,291),Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and inthe cities of Chongqing (132), Beijing (19), and Shanghai (13). Most newcases had a travel history to Wuhan . Almost all the recent deaths occurredin Hubei Province. Twenty more patients have recovered and beenNIH-002128discharged. More than 4,600 confirmed cases (including> 100 deaths)have occurred since December 8, 2019.A total of 13 additional , exported, confirmed cases have been reported(through January 28, 2:00 p.m. EST) since Monday, January 27. Morethan 25 cases have been exported in the past 7 days. Cases reportedsince Monday arrived in the following countries on the dates shown:Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20and 21 ), France (arrival date unknown), and Thailand (arrival datesunknown). All of these cases had travel history to Wuhan or contact withan ill person from Wuhan while in China .In addition to these exported cases, 7 locally acquired cases have beenreported since Monday in Germany (4), Japan , Taiwan and Vietnam. Thecases in Japan, Taiwan , and Vietnam reported contact with an obviously illperson from China. In Germany all 4 cases had close contact in abusiness seminar with an apparently asymptomatic Chinese woman onJanuary 21 (who previously had contact with relatives from Wuhan) ; thewomen states symptom onset was on a flight to Shanghai on January 23,and she was later confirmed to have 2019-nCoV. Incubation periods inthese cases have been as short as 3 days. In light of the secondary casesin Germany in a business setting, the most cautious approach of havingarrivals stay at home or in a hotel for 14 days after their last possibleexposure in China is increasingly justified.Updated travel advisories include: 1) Australia: reconsider travel to China;2) Canada: avoid all travel to Hubei Province; 3) Finland: avoidnonessential travel to Hubei Province; 4) France: avoid all travel to HubeiProvince; 5) Germany: avoid nonessential travel to China and avoid alltravel to Hubei Province; 6) India: avoid all nonessential travel to China; 7)New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid allnonessential travel to China.Singapore now denies entry to residents of Hubei Province and those whohave traveled there in the past 14 days.Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, YevreyskayaOblast) in Far Eastern Federal District, Russia have closed their landborders with China.Bangladesh , Canada, India, Kazakhstan , Russia, and South Korea arearranging flights to repatriate their respective citizens from Wuhan. Thesepersons will be closely monitored and present little threat of onwardtransmission.All tourist attractions in Tibet Autonomous Region have been closed .Current influenza vaccination is recommended to decrease the risk ofsimple influenza being mistaken for 2019-nCoV upon return.Infection control supplies have been depleted in medical facilities in thesmaller cities in central China; the situation is critical in many areas andresupply is uncertain.NIH-002129OVERALL RISK ASSESSMENTThe epidemic in China is months from peaking . A report indicates that justprior to the cordoning off of Wuhan, over 5 million residents (manypotentially infectious) left for other parts of China, and many thousands leftfor Hong Kong, Singapore, Thailand, and Japan. Exported cases have sofar been to countries likely to be capable of controlling (but not preventing)ongoing transmission, which will inevitably occur. In light of the secondarycases in Germany in a business setting , the most cautious approach ofhaving arrivals stay at home or in a hotel for 14 days after their lastpossible exposure in China is increasingly justified.Based on increasing data on virology, clinical presentation, andtransmission, this coronavirus closely resembles SARS-CoV in manybehaviors. Fortunately , sequential sequencing of viral isolates over timeindicate no significant new viral mutations ; mutations often increasetransmission or virulence . WHO assesses the risk of this event to be veryhigh in China , high at the regional level, and high at the global level. Theclosing of Wuhan airport and the major cities of Hubei province have yet tostem the flow of exported cases . The originally implicated animal market,now closed indefinitely, bears little relevance to the ongoing situation.Whether the market was the focus of a species jump from animals tohumans or merely one of multiple amplification settings for initial cases isincreasingly unclear. The degree of human-to-human spread outside ofHubei province remains unclear . A reproductive number, Ro, is estimatedat 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Rogreater than 1 indicates that each case leads to more than 1 subsequentcase, making control much more difficult. The spectrum of diseasemanifestations in a large cohort study has yet to be disclosed; a severecase rate of 20% has been consistent. The existence of mildlysymptomatic and asymptomatic infectious cases could increase the risk ofglobal spread. Case fatality is impossible to ascertain at present, andlesser or greater clinical virulence compared to MERS-CoV or SARS-CoVremains speculative.See 20 19 Novel Coronav irus Outbreak for detailed information .© 2020 Shoreland , Inc. All rights reserved .Travax News Alert items are incorporated into Shoreland's subscriptions .Travax content represents decision-relevant, expert synthesis of real-timedata reconciled with new and existing available advice from authoritativenational and international bodies .For email service changes , please forward this message toservice@shore land.com with your request. If the change should apply toall email subscriptions (Content Changes , Literature Watch and NewsAlert), please specify that in your request. [Account: SI53213; Recipient:bg.richard.tubb@gmail.com)NIH-0021302019 Novel Coronavirus Outbreak ReportcomprehensiveLast updated January 28, 2020.What's NewAccording to regional health authorities, more than 1,800 additional, confirmed cases(including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV)have been reported since January 27, 2020, throughout the country, mainly in theprovinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan(143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most newcases had a travel history to Wuhan. Almost all the recent deaths occurred in HubeiProvince. Twenty more patients have recovered and been discharged. More than 4,600confirmed cases (including> 100 deaths) have occurred since December 8, 2019.A total of 13 additional, exported, confirmed cases have been reported (throughJanuary 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have beenexported in the past 7 days. Cases reported since Monday arrived in the followingcountries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22),Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival datesunknown) . All of these cases had travel history to Wuhan or contact with an ill personfrom Wuhan while in China.In addition to these exported cases , 7 locally acquired cases have been reported sinceMonday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan,and Vietnam reported contact with an obviously ill person from China. In Germany , all 4cases had close contact in a business seminar with an apparently asymptomaticChinese woman on January 21 (who previously had contact with relatives from Wuhan);the woman states symptom onset was on a flight to Shanghai on January 23, and shewas later confirmed to have 2019-nCoV. Incubation periods in these cases have beenas short as 3 days. In light of the secondary cases in Germany in a business setting,the most cautious approach of having arrivals stay at home or in a hotel for 14 daysafter their last possible exposure in China is increasingly justified .Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada:avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to HubeiProvince ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessentialtravel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessentialtravel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid allnonessential travel to China .Singapore now denies entry to residents of Hubei Province and those who havetraveled there in the past 14 days.Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) inFar Eastern Federal District, Russia have closed their land borders with China .Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flightsto repatriate their respective citizens from Wuhan. These persons will be closelymonitored and present little threat of onward transmission.NIH-002131All tourist attractions in Tibet Autonomous Region have been closed.Current influenza vaccination is recommended to decrease the risk of simple influenzabeing mistaken for 2019-nCoV upon return.Infection control supplies have been depleted in medical facilities in the smaller cities incentral China; the situation is critical in many areas and resupply is uncertain.Overall Risk AssessmentThe epidemic in China is months from peaking. A report indicates that just prior to thecordoning off of Wuhan, over 5 million residents (many potentially infectious) left forother parts of China, and many thousands left for Hong Kong, Singapore, Thailand, andJapan. Exported cases have so far been to countries likely to be capable of controlling(but not preventing) ongoing transmission, which will inevitably occur. In light of thesecondary cases in Germany in a business setting, the most cautious approach ofhaving arrivals stay at home or in a hotel for 14 days after their last possible exposurein China is increasingly justified.Based on increasing data on virology, clinical presentation , and transmission, thiscoronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequentialsequencing of viral isolates over time indicates no significant new viral mutations;mutations often increase transmission or virulence. WHO assesses the risk of this eventto be very high in China , high at the regional level , and high at the global level. Theclosing of Wuhan airport and the major cities of Hubei province have yet to stem theflow of exported cases. The originally implicated animal market , now closed indefinitely ,bears little relevance to the ongoing situation. Whether the market was the focus of aspecies jump from animals to humans or merely one of multiple amplification settingsfor initial cases is increasingly unclear . The degree of human-to-human spread outsideof Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.4-2.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1indicates that each case leads to more than 1 subsequent case, making control muchmore difficult. The spectrum of disease manifestations in a large cohort study has yet tobe disclosed; a severe case rate of 20% has been consistent. The existence of mildlysymptomatic and asymptomatic infectious cases could increase the risk of globalspread . Case fatality is impossible to ascertain at present , and lesser or greater clinicalvirulence compared to MERS-CoV or SARS-CoV remains speculative .Current Disease SituationMore than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) haveoccurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly inWuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui(106); in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 otherprovinces throughout the country. An additional 6,900 suspected cases have beenreported since January 21, 2020. In the setting of a large outbreak and with increaseddelays in testing, a high proportion of suspected cases will evolve into confirmed cases.Seventy-nine cases have been discharged. Two-thirds of the cases are male. Theyoungest case is 10 years old and the oldest is 89; more than 70% of cases are over 40years old, but the co-morbidity profiles of most cases are unknown .NIH-002132The number of persons becoming infected with the virus has been doubling every sixdays. The outbreak in China is not approaching peak, and modeling indicates that ismonths away.Exported CasesSeventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented atinternational ports of entry January 6-25 in 16 countries. Of these cases, more than 25cases arrived in the past 7 days.All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in Chinaand symptom onset dates after December 31, 2019; none had visited the implicatedmarket.Australia (5 cases): One case traveled while asymptomatic aboard China SouthernAirlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalizedon January 23. Contact tracing is underway; movement around Melbourne was limitedprior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights toSydney, New South Wales State on January 6, 18, 20, and 23, and were hospitalizedon January 15, 20, and 24. One of the patients had limited movement around Sydneyprior to isolation; movement history for the other 3 cases is unknown.Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukvilleon January 23, 2020, and developed symptoms on January 25.Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlinesflight CZ311 to Toronto, Ontario Province on January 22. The first case wassymptomatic while traveling and was hospitalized on January 23. The second case wasunder self-isolation and was confirmed on January 27. Contact tracing is underway;patient movement around Toronto was limited prior to isolation .France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris onJanuary 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travelhistory for the fourth case in unknown. All cases were hospitalized.Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25;the first aboard a train to West Kowloon, the second aboard a flight to Hong KongInternational Airport , and the third to Lo Wu Control Point. Four of the cases traveledwhile asymptomatic aboard trains on January 19 and 22. The last case traveled withdiminished symptoms aboard a train on January 23. All cases were hospitalized .Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight toKanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January19. The first was hospitalized on January 10 and discharged on January 15 followingrecovery, and the second was hospitalized on January 22. Another 2 cases traveledwhile asymptomatic: the first aboard a flight to Tokyo on January 18 and the secondaboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January23, and the second was hospitalized on January 24. The remaining 2 cases arrived onJanuary 20 and 21 in Aichi and Tokyo prefectures.Macau (7 cases): The first case traveled while asymptomatic aboard a train and a buson January 19, and the second case traveled while symptomatic (travel methodunknown) on January 22. The first case was hospitalized on January 19 and the secondNIH-002133case on January 21. The third case traveled aboard a ferry on January 23 and wasimmediately hospitalized. Three cases traveled (methods unknown) on January 22; allwere hospitalized. The last case traveled while asymptomatic on January 23 and washospitalized January 27.Malaysia (4 cases) : The first case traveled while asymptomatic aboard a bus to JoharBaharu on January 22 and was hospitalized on January 23. The remaining 3 casestraveled (method unknown) to Johar Baharu on January 23; all were hospitalized .Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized onJanuary 13, and was discharged on January 17 following recovery.Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights onJanuary 18, 19, 20, 21, 22, and 23.South Korea (4 cases): Two cases traveled while symptomatic to lncheon InternationalAirport and to Gimpo International Airport on January 19 and 23, and both wereimmediately hospitalized. The remaining cases traveled while asymptomatic on January20 and were hospitalized on January 25.Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, anddeveloped symptoms on January 25.Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 casesarrived at Taiwan Taoyuan International Airport.Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airporton January 8, 13, and 19 and were hospitalized; the travel history of the fourth case isunknown. The fifth case traveled to Bangkok on January 21 and was hospitalized onJanuary 23. The travel histories of the remaining 9 cases are unknown.U.S. (5 cases): Two cases traveled while asymptomatic: the first to O'Hare Internationa lAirport on January 13 and the second to Seattle-Tacoma International Airport onJanuary 15. The first was hospitalized several days after arrival, and the second washospitalized on January 19. The remaining 3 cases were reported in Maricopa County,Arizona and Los Angeles and Orange counties, California ; information on the patients'travel histories are unknown. Contact tracing for all cases is underway. The first casereported limited movement around Chicago prior to hospitalization; movement historyfor the other 2 cases in unknown.Vietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized onJanuary 22 in Ho Chi Minh City.In addition to these exported cases, 7 locally acquired cases have been reported sinceMonday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan,and Vietnam reported contact with an obviously ill person from China. In Germany, all 4cases had close contact in a business seminar with an apparently asymptoma ticChinese woman on January 21 (who previously had contact with relatives from Wuhan);the woman states symptom onset was on a flight to Shanghai on January 23, and shewas later confirmed to have 2019-nCoV . Incubation periods in these cases have beenas short as 3 days.Entry/Exit ScreeningNIH-002134In a reversal of long-standing policy, WHO now recommends that all countriesimplement temperature screening at points of entry for passengers arriving from 2019-nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunicationmessages at points of entry to later capture asymptomatic persons whoare in the incubation phase.In early January , some exit screening was implemented at Wuhan Tianhe InternationalAirport (nonstop flights to Istanbul, London, New York, Osaka, Paris, Rome, SanFrancisco, Tokyo, and major hubs throughout Southeast Asia), as well as at 3 major railstations in Wuhan . More restrictive screening was instituted on January 15 in Hubeiuntil cessation of international flights on January 23. Despite exit screening at allinternational airports in China in the past week, significant numbers of cases continue tobe exported.Entry screening at international ports of entry has been or is being implemented asnoted below, and anyone with fever and respiratory symptoms who has been to 2019-nCoV-affected areas in the previous 14 days will be detained and isolated at theselocations:Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , OranAhmed Ben Balla AirportBurma (Myanmar) : Yangon International AirportEgypt: Cairo International Airport (all flights from China)Hong Kong: All border checkpoints , including Hong Kong Internationa l Airport and therailway station in West KowloonIndia: Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai internationalairports (all flights from China and Hong Kong)Italy: Leonardo da Vinci-Fiumicino AirportIran: Tehran Imam Khomeini International Airport (all flights from China)Macau: Macau International AirportNorth Macedonia: Skopje International Airport (connecting flights from Asia)Qatar: Hamad International Airport (all flights from China)Russia: Moscow, Irkutsk Oblast, and Yekaterinburg international airports and points ofentry in Amur OblastSingapore : Changi AirportSouth Africa : O.R. Tambo International Airport (all flights from China)South Korea: lncheon International AirportTaiwan: All international airportsNIH-002135Thailand : Krabi, Suvarnabhumi, Don Mueang, Phuket, and Chiang Mai airportsTurkey: All international airports (all flights from China)United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport(all flights from China)U.K.: Heathrow International AirportU.S.: Twenty points of entry, including Hartsfield-Jackson Atlanta International Airport,John F. Kennedy International Airport, Los Angeles International Airport , O'HareInternational Airport , and San Francisco International Airport. Travelers from Wuhanmay have their temperatures taken and/or be required to complete a symptomquestionnaire; travelers with symptoms (fever, cough, difficulty breathing) will bedeta ined for additional assessment.Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana,Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal,Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka,Tajikistan, Tunisia, Vietnam : Airports and other ports of entryTravel AdvisoriesThe following countries and/or organizations have published travel recommendations:Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France ,Germany , Japan, Mexico , New Zealand , U.K., U.S.Avoid Nonessential Travel to Hubei Province: Finland, UkraineAvoid All Travel to China: None at presentAvoid Nonessential Travel to China: Australia, Germany, India, Taiwan , U.S.No Advisory: WHOTravel RestrictionsDifferent levels of travel restrictions are in effect:No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air SeoulNo Flights from Wuhan: Wuhan Airport is closed to all international and domesticflights.Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea, Russia (AmurOblast , Khabarovsk Krai, Jewish Autonomous Oblast in Far Eastern Federal District);high speed rails and ferry services suspended in Hong KongNo Residents from Hubei Province: Hong Kong, Macau, and Singapore (includingvisitors in past 14 days), Malaysia , and TaiwanNIH-002136Internal Travel Restrictions in China: Major cities in Hubei Province have instituted atravel ban on occupants of their cities, suspending urban buses, subways , ferries , andlong-distance passenger transport from the cities, including flights and trains , andclosing intercity roads. lnterprovince shuttle buses in major areas have stopped. Manybars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , andmany other affected areas. Major tourist attractions have closed in Beijing, Shanghai ,Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China hasstopped all inbound and outbound tour groups but not individual travel. Internal travelfor the Lunar New Year Holiday has been severely limited by the government , andpublic gatherings are forbidden. The reopening of schools and universities has beenpostponed in many areas. Shanghai has temporarily closed all nonessentialworkplaces. Visitors from Hubei Province will be actively monitored for 14 days inHaikou, Hainan Province.No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa mustspend at least 14 days in a country free of 2019-nCoV and undergo medical clearanceprior to travel to Samoa.Australia , Bangladesh, Belgium, Canada, France, Germany, India, Japan, Kazakhstan ,Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. arearranging flights to repatriate their respective citizens from Wuhan. These persons willbe closely monitored and present little threat of onward transmission .TransmissionThe detailed epidemiology of possible causative animal exposures and zoonotictransmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked toSouth China Seafood City market in Jianghan District, which sold seafood and otherwildlife (including birds). More than 580 environmental samples, without indication as towhether animal tissue was included , were collected from the implicated market. Ofthese , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-originpoint of the large-scale outbreak. Thirty-one of the positive samples (94%) werecollected from the western part of the market, where wildlife was traded. The firstpublished epi-curve shows that the symptom onset date of the first patient identified inthe outbreak was December 1, 2019. The patient reported no exposure to theimplicated market; no epidemiological link has been detected between this case andlater cases. This finding raises the possibility of an initial jump of 2019-nCoV directlyfrom bat to human, with subsequent initial human-to-human propagation within theseafood market.Infected intermediate animal hosts, if they exist, may still be present in the supply chain.South China Seafood City market, now closed indefinitely , remained in operationthrough December 31, 2019. Other points of infection would be likely because manysubsequent cases had no contact with the implicated market. Chinese authorities havenow stated that human-to-human transmission is in the fourth generation in Wuhan andat least the second generation elsewhere (mostly in clusters). A reproductive number,Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists.An R0greater than 1 indicates that each case leads to more than 1 subsequent case,making control much more difficult. Ro is not a constant number and changes with theongoing circumstances and evolution of an outbreak . One published cluster studyindicates asymptomatic shedding (but not transmission) by a single patient. Sequencedata from several small clusters indicate identical virus in all subjects within the cluster.NIH-002137More than 47,800 close contacts remain under surveillance (> 1,200 have beenreleased), and contact tracing is ongoing in affected provinces and municipalities.However, not all contacts are being ascertained or monitored adequately. As many as16 health care workers (HCWs) have been confirmed as infected by at least 1 case inWuhan in a potential super-spreading event, but overall infectivity for HCWs has notbeen established. No case of 2019-nCoV has been attributed to transmission on anaircraft .The survival rate of the virus on surfaces or in the environment is unknown. Disinfectionprocesses that are effective for other zoonotic coronaviruses should be followed fornow. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs,bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, cleanany surfaces that may have blood, bodily fluids, and/or secretions or excretions onthem. Use a diluted bleach solution or a household disinfectant with a label that says"EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l(1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) ofwater.Clinical ManifestationsMost cases have reportedly exhibited symptoms of fever, respiratory compromise, andbilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan.Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sorethroat) and diarrhea are not common. Overall, about 20% of the cases have beensevere or critical, including pneumonia , respiratory failure, and in some cases death.The existence of asymptomatic cases has not been ascertained. No known treatmentexists for 2019-nCoV, although remdesivir will be available shortly from the U.S. CDCfor compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir,ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlierliterature , the combined use of lopinavir and ritonavir is under study in China. Currentinfluenza vaccination is recommended to decrease the risk of simple influenza beingmistaken for 2019-nCoV upon return.In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58)conducted early in the epidemic (presentation before January 2), the most commonsymptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue(44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglassopacity with subsegmental areas of consolidation, whereas ICU patients hadbilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even inthis early cohort) had been exposed to the South China Seafood City market. The casefatalityrate was estimated to be 15%, but more severe cases tend to predominate earlyin an epidemic. Limited data from another published cluster study indicate a 3- to 6-dayincubation period similar to SARS-CoV and clinical and radiologic features similar toSARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1to 14 days.Virology2019-nCoV was initially isolated from 1 case and entirely sequenced; this informationwas published internationally by Chinese scientists on January 10. Electron microscopyof 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventhNIH-002138member of the family of coronaviruses that infect humans. Novel coronaviruses fromWuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage Bof the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoVand SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with asimilarity between different gene segments ranging from 60% to 90%. 2019-nCoVexhibits a 96.5% similarity to the known bat coronavirus precursors in the same viralclade.Sequence data allowed national laboratories to rapidly develop diagnostic kits, whichare now available in most developed countries and most Asian countries. HKU1, NL63,229E, and OC43 are human coronaviruses that are detected by some routine multiplexPCR panels used in routine clinical practice. These coronaviruses are associated withminor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV,and 2019-nCoV , these agents are not associated with major outbreaks or severerespiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings sofar strongly favor (but do not prove) causation. 2019-nCoV has been shown to use thesame cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lowerrespiratory tract specimens, which should be the primary specimen obtained. Predictionof human-to -human transmissibility from sequence data is difficult becausecoronaviruses vary widely in their transmissibility; coronaviruses acquired from animalsgenerally have some potential for human-to-human transmission. Evidence fromsubsequent whole genome sequences acquired over the last several weeks show littlegenetic variation, indicating that the virus jumped from an animal reservoir to humanswithin the last few months. Identical recent mutations in epidemiologically unlinkedcases support sustained human-to-human transmission.Criteria for Testing of Suspected CasesU.S. CDCPersons meeting the following criteria (clinical features and epidemiologic risk) forsuspected cases of 2019-nCoV will be considered persons under investigation (PUI):• Fever and symptoms of lower respiratory illness (e.g., cough, shortness ofbreath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoVwhile that person was ill in the past 14 days before symptom onset• Fever or symptoms of lower respiratory illness (e.g., cough, shortness ofbreath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past14 days before symptom onsetHCWs entering the room with a PUI should use standard precautions, contactprecautions , airborne precautions , and eye protection (e.g., goggles or a face shield).PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they areidentified and be evaluated in a private room with the door closed, ideally an airborneinfectionisolation room if available.PreventionTravelers going to Wuhan should avoid animals (alive or dead), animal markets,products that come from animals (such as uncooked meat), and contact with illappearingpersons. Quality of infection control at medical facilities in Wuhan isuncertain, and those with minor medical problems should avoid busy medical settings.NIH-002139Infection control supplies have been depleted in medical facilities in the smaller cities incentral China; the situation is critical in many areas and resupply is uncertain. Travelerswho develop fever and respiratory symptoms within 14 days of travel to Wuhan shouldimmediately be isolated, and public health authorities should be alerted.Employees, Students , Visitors , All Others Coming from WuhanWhether asymptomatic individuals infected with 2019-nCoV are infectious to others isunknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset.SARS-CoV did not transmit until 4 days after symptom onset, which led to itseradication because all contacts with fever could be promptly identified and isolated.If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitorby taking a temperature reading immediately prior to coming into the workplaceor school for 14 days after their last exposure in Wuhan. Arrivals with fever at any timeshould self-report to public health authorities (or telephone ahead before presenting toa hospital) and should wear a mask as soon as possible. A more stringent approachwould require that an employee, student, or visitor-upon arrival to a workplace orschool- be instructed to perform an additional temperature check in the presence ofmedical personnel to ensure compliance with local self-monitoring requirements. Inaddition, prior to any gathering of~ 2 persons, attendees could be required to performadditional self-monitoring .Based on advanced information and employee or visitor medical screening, additionalpreventive measures may be required (e.g., increased ventilation, larger meeting roomswith more personal space per participant , disinfection of work areas and lavatories, andprovision of alcohol wipes).The most cautious approach would be for arrivals to stay at home or in a hotel for 14days after their last possible exposure in China. To date, all known cases exported toother countries had either visited Wuhan or had contact with an ill person from Wuhanwhile in China.Sent from my magical iPad!On Jan 29, 2020, at 2:46 PM, Richard Tubb <bg.richard.tubb@gmai l.com>wrote:Richard J. Tubb, MDBrigadier General (retired)White House Physician EmeritusFrom:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAID) [E)Thu, 6 Feb 2020 04:03:31 +0000Howard BauchnerConrad, Patricia (NIH/NIAID) [ElRE:Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawedThanks, Howard. Talk soon.-----Original Message-----From: Howard Bauchner <Howar d.Bauch11er@jamanetwork .org>Sent: Wednesday , February 5, 2020 6:37 AMTo : Fauci , Anthony (NTTI/NIAID) [E] ------~~Cc : Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,...Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+w i thout+ symptom s+was+ fl a wedThe author of our case-series - proof today will send to you - is an ICU doc in Wuhan - trained with Derek Angus -he has been great - but I have asked him about himself, bis family - we loss track of the personal - which is soimportant.J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couplemajor car accidents; etc. Also worked at the Berhorst Clin ic in Guatemala in 1978 (before there was global health)numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving.Try to take a break; have a good glass of Claret on me.HCB----- Original Message -----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)>Sent : Wedne sday , February 05 , 2020 5:31 AMTo: How ard Bauchner <How ard.Bauchner@jamanetwork.org>Cc: Conrad , Patric ia (NIH/NIAJD) [E] (b) (6)>Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was+flawed[Warning External Email)Howard:Your outline looks fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was onevery other night and every other weekend, hut actually never left the hospital because the patients were so sick.Best,Tony----- Original Messag e-----From: Howard Bauchner <Howard .Bauchn er@jamanetwork.org>Sent: Wednesday , February 5, 2020 6:-23- A-M- ----, a-s-r,= To: Fauci, Anthon y (NIH/NIAID) [E] CbHSubject: RE: Study+claiming+new+corona virus+can+be +transmitted+by +people +without+symptoms +was+flawedLikely come up tomorrow in our discussio n - not NEJM pape r but just the concept.Outline if OK with youNIH-002140What's up in ChinaWhat's up around the worldWhat's up in USAnd then more specific questionsls this more like HIN! than MERSCan we really know mortality risk (denom inator problem).Incubation periodHow "infectious"News on treatmentQuarantine workingSound OK?You surviving - worried a bit about your workload.HCB-----Original Message- ----From: Fa uci, Anthony (NTH/NlAID) [E] (b)(6) >Sent: Wednesday, February 05, 2020 5:20 AMTo: Howard Bauchner <Howard.Bauchner @jama netwo rk.org>Subject: RE: Srudy+claimi ng+new+corona virus+can+be+transm itted+by+people +without +symptoms +was+tlawed[Warning External Emai l]The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to theDirector of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China.-----Original Message-----From: Howard Bauchner <Howard .Bauchner@jamanetvvork .org>Sent: Wednesday, February 5, 2020 6:-1-5 -A-M-- ~-= To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) >Subject: FW: Study+claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawedTonySuspect you saw this. Big problem if true - rushing to publication - leads to big mistakes.HCB-----Original Mcssage ----------- --:;;=a<, From: Redberg, Rita (b) (Sent: Wednesday , February 05, 2020 5: 13 AMNIH-002141NIH-002142To: Howard Bauchner <Howard.Bauchner @jamanetwork.org >; Phil Fontanarosa<Phil.Fontanarosa @jamanetwork.org >Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed[Warning External Email]Assume you saw, but.hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon-2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s-2Dwrong&d=Dw IF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFUZ7y8a6zr8BltW A4gtfR WytiKtFo VM&m=4xruNHFPsXovMmiMLZWiD9OzCNhiiGOKmtHhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwBnAiRXsktAbH l rM9a3j PY &e=From:Sent:To:Fauci, Anthony (NIH/ NIAIO) [E)Thu, 6 Feb 2020 03:59:46 +0000Auchincloss, Hugh (NIH/ NIAID) [C]- ---------- (b)(6) Subject: FW: touc hing base about Texas Biomedical Research Institut ePlease take care of this.From:L arry Schlesinger ----------- (b)(6) Sent: Wed nesday, February 5, 2020 8:42 AMTo: Auchincl oss, Hugh (NIH/NIAID) [E] ----------=- (b')""('= >; Fauci, Antho ny (NIH/N IAID) [E](b)(6)Subject: to uching base about Texas Biomedical Research Insti tuteHi Tony and Hugh.I know that I am writing to you at a busy time during yet another infectious diseaseoutbreak that is rapidly evolving . However, I wanted to send you a brief note to updateyou about the transformational change going on in the landscape of our free standinginstitute with its new, sharply defined goal to be the global leader in eradicatinginfectious disease threats in the world . I know that you are familiar with us.I have been leading the institute since June of 2017 and currently finishing year one of a10 year board-approved plan of growth in our scientists , educationa l programming andcampus modernization. I believe that you are aware that we house the only privateBSL4. We also just opened our newest of 5 BSL3 facilities , this newest one being nearly8000 sq. ft. with capacity for ~100 NHPs, small animals, a complete aerosol suite and aPET CT. We also house the SNPRC, now under the leadership of Deepak Kaushal(who replaced Robert Lanford) and with the largest marmoset colony as a result ofrestructuring our building facilities (in addition to our other species . CbH4JPlease check out our newly designed website: www.txb iomed.org.The bottom line is that I left university life to lead an organiza tion that is determined tonot only discover critical, new fundamental science but also effectively and efficientlybring it full forward to create portfolios for the FDA through our business model,nimbleness, regulated science culture (GLP level), longstanding public and privatepartners through contract science ( esp. BARDA), culture and community support .NIH-002143We want to help! Please let us know if and how we can contribute to this outbreak andundoubtedly others going forward .I truly appreciate your leadership. The country gets the voice of reason on infectiousdisease outbreaks through your public efforts. I enjoyed learning more about this duringmy time on council.Best,LarryLarry Schlesinger, MDProfessorPresident and CEOTexas Biomedical Research Institute8715 W. Military Drive, San Antonio, TX 78227Email: (b)(6)Teamwork I Integrity I Diversity I Excellence I SafetyExecutive assistant:(b)(~(b) (6) Phone==== (~b)~(6~) Mobi leEmail: I- -------- (b)(6)jCONFIDENTIALITYN OTICE:T his e-mail and any files and/or attachments transmitted, may containprivileged and confidential information and is intended solely for the exclusive use of the individual orentity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that anyreview, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. Ifyou have received this e-mail in error, please immediately notify the sender stating that thistransmission was misdirected; return the e-mail to sender; destroy all paper copies and delete allelectronic copies from your system without disclosing its contents.NIH-002144From:Sent :To:Cc:Subject:Bob:Fauci, Anthony (NIH/N IAID) [E)Thu, 6 Feb 2020 03:49:36 +0000Robert KnoblerCassetti, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [ElRE: Potential Approa ch to Wuhan CoronavirusThanks for your note. It was good to bear from you. I am copying Cristina Cassetti on this e-mail. Cristinadirects the extramural coronavirus research activities. Perhaps you two can connect to discuss researchopportunities.Best,Tony-----Original Message -----From: Robert Knobler ______ "(""b')'"c"='Sent: Wednesday , February 5, 2020 10-:5-5- A-M- ---:,,:,~ To: Fauci , Anthony (NIH/N IAJD) [E] ----,----- (b)(6) > Su~ j e ct: Potential Approach to Wuhan CoronavirusDear Dr. Fauc i,You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgotyour enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984.l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, andeventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor.Lacking the correct receptor or blocking binding of the virus spike protein to the receptor with monoclonalantibodies blocked infection .On to the present problem of human coronaviruses . Vaccines will take a long time for the current crisis. Theangiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlierstudies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs aspotential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct ,there may still be sufficient untainted supplies of ARBs, such as irbesar tan, available, or production can be scaledup, if this truly is the eve of a pandemic.Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me bye-mail or my cell phone.T also did do clinical trials while with Mike, and then when I joined the neu rology faculty of Jefferson inPhi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work. Foranother time, I also have some novel ideas on how HIV become s AIDS, as well. Ironica lly, these ideas were basedupon observations I made during my analy sis ofMHV.All the Best ,Rober t L Knobler, MD, PhD(b)(6)NIH-002147From:Sent :To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Thu, 6 Feb 2020 03:28:54 +0000Cohen, ElizabethRE: treatment protocolsThe Chinese are putting together protoco ls to test certain drugs such as remdesivir.From: Cohen, Elizabeth <Elizabeth.Cohen@turner.com>Se nt: Wednesday, February 5, 2020 3:19 PMTo: Fauci, Anthony (NIH/NIAID) [E]-------=- (bc)(-=c >Subject: treatment protocolsHi Tony,We were wondering if there are any part icular protocols being suggested for treating the Wuhancoronavirus cases in the US. Are there discussions among the teams caring for these patien ts about thebest approach?Many thanks.Best,ElizabethElizabeth Cohen, MPHCNN Senior Medical CorrespondentNIH-002148From: Fauci, Anthony (NIH/NIAID) [ElSent : Thu, 6 Feb 2020 02:54:42 +0000To: Cassetti, Cristina (NIH/NIAID) [ElSubject : FW: Corona virus/sepsis treatmentAttachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc,REFERENCESC orona Virus .docxPlease handle.From : stanley satz (b)(6)Sent: Wednesday, February 5, 2020 7:20 PM ------ == To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _______ _.Subject: Corona virus/sepsis treatmentDear Dr. Fauci,(b) (4)NIH-002150Best regards,Stanley Satz, Ph.D.Chairman and Chief Scientific OfficerAdvanced Innovativ e Partners, Inc.Professor, Florida Atlantic University,Universi ty of Miami School of Medicinewww .advanced innovativepartners .comwww .bionucleo nics.com(b)(6)Confidentiality NoticeThis message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity towhich it is addressed. This communication may contain information that is proprietary, privileged or confidentialor otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized toread, print, retain, copy or disseminate this message or any part of it. If you have received this message inerror, please notify the sender immediately by e-mail and delete all copies of the message.NIH-002151(b) (4)From:Sent:To:Cc:Fauci, Anthony (NIH/NIAID) [E)Thu, 6 Feb 2020 02:54:19 +0000Conrad, Patricia (NIH/NIAID) [E)Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [ElSubject: FW: Dr. Levitt summar izes CDC 2019-nCoV Committee Report released today 5Feb 2020Attachments: M and M Wuhan Virus .pdfSee me about getting someone to prepare a response.From: Robert Levitt (b)(6bSent: Wednesday, February 5, 2020 7:50 PMTo: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) -------- (b)(6) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020Dear Secretary Azar and Dr. Fauci,I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV)epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's bestPh.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report.Below I have recorded what I think the most important facts in the report for Secretary Azarand other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying allinfected persons and their contacts . I have also added my personal thoughts on how to stopt he spread of this novel coronavirus and a persona l fear I have communicated to Secretary Azarin the past:-- President Trump signed an order preventing entry into the U.S. of any person who hastrave led to mai nland China (PRC). Exceptions in clude U.S. citizens and permanent residents andt heir famil ies. Thank you Mr. Trump.-- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r ealt ime'.-- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s.The number of ports and especia lly airports needs to be increased. The Report states that14,000 Chinese enter the U.S. daily. If the 5 airports receive 85% of these Chinese, then 2,100Chinese enter the U.S. daily at other airports without enhanced screening.-- CDC has developed its own RT-PCR test to detect 2019-nCoV in respiratory specimens. I have readcase reports where state laboratories have required too much proof of suspected Wuhan virus fromclinicians before perfo rming RT-PCR testing of specimens. CDC should provide their improved RT-PCRtest to all states and HHS should insure that all states have sufficient equipment and trainedpersonnel for rapid turn-around time.NIH-002152NIH-002153-- CDC has grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus toresearchers with verified credentials and vetting in a safe and monitored procedure.-- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in aseparate room with a N95 face mask so that they are not in range of other patients. HCWshould wear personal protection: gloves, gown, face shield or N95 mask and goggles.-- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S.CDC is doing a terrific job in getting the message out to clinicians and the public.Sent from OutlookFrom:Sent:To:Cc:Subject:Tak:Fauci, Anthony (NIH/NIAIO) [E)Thu, 6 Feb 2020 00:56:18 +0000Mak, TakCassetti, Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E]RE: An IdeaThanks for the note . It likely will be more efficient if I refer you to the programpeople in my Institute who could go over these data with you and then get meinvolved later . The reason that is tha t I am doing 18 hours pe day (seriously) aspart of the White House Task Force and it would very difficult for me to fit in ameeting to go over data. I have copied Dr. Cristina Cassetti who runs ourcoronavirus extramural research program . I will ask her by this e-mail to contactyou to have our people discuss your work with you.Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone Cb()6 )FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Mak, Tak (b)(6)Sent : Wednesday, February 5, 2020- -7:-30- -P-M- =-,--=, To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)(6) Subject: An IdeaDear Tony,It has been a while since we discussed science.NIH-002155(b) (4)(b) (4)Best regards, TakThis e-mail may contain confidential and/or privileged informat ion for the sole use of the intendedrecipient.Any review or distribution by anyone other than the person for whom it was originally intended isstrictly prohibited.If you have received this e-mai l in error, please contact the sender and delete all copies.(b)(4)Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization.If you feel you have received an email from UHN of a commercial nature and would like to be removedfrom the sender's mailing list please do one of the following :(1) Follow any unsubscribe process the sender has included in their email(2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in thesubject line. If you require additional information please go to our UHN Newsletters and Mailing Listspage.Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists.NIH-002156From:Sent:To:Cc:Subject :Jeremy:Fauci, Anthony (NIH/NIAIO) [E)Thu, 6 Feb 2020 00:00:36 +0000Jeremy Farrar;Collins, Francis (NIH/OD) [ElJosie Golding;Tabak, Lawrence (NIH/OD) [ElRE: Prevalence of infect ion and stage of the epidemic in WuhanI left out an important name for the coronavirus evolution working group.Please include her: Pardis Sabeti at the Broad Institute of MIT and HarvardThanks,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520Nation al Institutes of HealthBethesda , MD 20892 -2520Phone: (b)(6)FAX : (301 496-4409E-mail Cb()6 )The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Fauci, Anthony (NIH/NIAID) [E]Sent: Wednesday, February 5, 2020 5:25 PMTo: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] ------- (b)(6)Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E](b)(6)Subject: RE: Prevalence of infection and stage of the epidemic in WuhanJeremy:Thanks for the note. Looks like things are moving along with WHO. I will list below anumber of names for potential members of the working group to examine the evolutionary originof the 2019-nCoV in addition to the individuals who were on the call with us last Saturday:Harold Vannus - Weill Cornell Medical Center - New York CityFeng Zhang - MIT (CRISPR expe11)Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhanstrain vs other bat viruses and the SARS virus)NIH-002157Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knowsmore about hepadnaviru ses but an outstanding clinical and basic viro logist)John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over thealleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic ML V)Eugene Koonin - NCBI/National Libreary of Medicine , NIH;ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/)Wayne Hendrickson - Columbia University and the New York Structura l Biology CenterGary Nabel - Sano:fi (Boston)Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Jeremy Farrar (b)(6)Sent: Wednesday, February 5, 2020 6:21 AMTo: Fauci, Anthony (NIH/NIAID) [E] -------= (b-):(--6=)=; Collins, Francis (NIH/OD) [E](b)(6)>Cc: Josie Golding (b)(6)Subject: Re: Prevalence of infection and stage of the epidemic in WuhanFrancis and TonyCouple of things:• I spoke again with WHO this morning. I believe they have listened and acted. Let me know ifyou agreeo At the WHO meeting next week they will set up the Group who will "look at the originsand evolution of 2019n-CoV"o They have asked for names to sit on that Group - please do send any namesNIH-002158o We can have a call this week with a core group of that to frame the work of the Groupinclud ing - if you could join?o I think this puts it under the umbrella of WHO, with action this week and into nexto With names to be put forward into the Group from us and pressure on this group fromyour and our teams next week.• The team will update the draft today and I will forward immediate ly -they will add furthercomments on the glycansDoes that sound reasonable to you?JeremyFrom: "Fauci, Anthony (NIH/NIAID) [E]" ---------(b)(6)Date : Tuesday, 4 February 2020 at 13:18To: Francis Collins CbH6)>, Jeremy Farrar ----------- (b)(6) Subject: RE: Prevalence of infect ion and stage of the epidemic in Wuhan?7Anthony S. Fauci , MDDirector(b) (4)National Institute of Allergy and Infectious DiseasesBu ilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail (b)(6) ______.. _The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Collins, Francis (NIH/OD) [E] (b)(6)Sent : Tuesday, February 4, 2020 6:12 AMTo: Jeremy Farrar (b)(6)Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: RE: Prevalence of infection and stage of the epidemic in WuhanYes, --------------------------------- (b) (4)FrancisNIH-002159From: Jeremy Farrar (b)(6)Sent: Tuesday, February 4, 2020 6:08 AM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>Subject: Re: Prevalence of infection and stage of the epidemic in WuhanOn 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El ------- (bH > wrote:Very thoughtful analysis. (b)(4)FrancisFrom: Jeremy Farrar (b)(6)Sent: Tuesday, February 4, 2020 2:0-1- A-M- ----=-<-= To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>; Collins, Francis (NIH/OD) [E)(b)(6)Subject : FW: Prevalence of infection and stage of the epidemic in WuhanPlease treat in confidence - a very rough first draft from Eddie and team - they will sendon the edited , cleaner version later .Pushing WHO again todayFrom: Edward Holmes (b)(6J>Date: Tuesday, 4 February 2020 at 06 :33To: Jeremy Farrar (b)(6J>Subject: Re: Prevalence of infection and stage of the epidemic in WuhanHere's our summary so far . Will be edited further.It's fundamental science and completely neutral as written. Did not mention otheranomalies as this will make us look like loons. As it stands it is excellent basic science Ithink, which is a service in itself.NIH-002160(b) (4)(b) (4)Will finish as soon as we can.PROFESSOR EDWARD C. HOLMES FAA FRSARC Australian Laureate FellowTHE UNIVERSITY OF SYDNEYMarie Bashir Institute for Infectious Diseases & Biosecurity,School of Life & Environmental Sciences and School of Medical Sciences,The University of Sydney I Sydney I NSW 120061 Australia(b)(6)(b)(NIH-002161From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Wed, 5 Feb 2020 20:52:29 +0000Conrad, Patricia (NIH/NIAID) [E)FW: note to Patty -- and Tony FauciLet us discuss. Steve is a good guy, but I do not want to kill myse lf trying to dotoo many thingsdat the same time .Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail Cb) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Conrad, Patricia (NIH/NIAID) [E] ---------(b)(6)> Sent: Wednesday, February 5, 2020 3:27 PMTo: NIAID OD AM <NIAIDODAM@niaid.nih.gov>Subject: FW: note to Patty-- and Tony FauciPatricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520- Room 7A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaime r:The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive information. It shOuld not be usedby anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete itNIH-002164from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not acceptliability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives.From: Steve Clemons <sclemons@t hehill .com>Sent : Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)_- _-_-_-_-__-_-_-_-__-_-_-_-_- ---~= C_Hb_6)Subject : note to Patty -- and Tony FauciGreetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on ourpreparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one morerequest to your pile to think about.. .. and I am trying to see if what I am suggesting might work rightbefore your Aspen talk next Tuesday at noon.In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al JazeeraEnglish that runs four times a week on thei r global network and is garnering between 100k-200k views aweek on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of threeexperts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator onwhat we should do not only on the coronavirus but in general on the infrastructure of pandemicpreparedness in the country -- sort of a shorter form of that great PBS show you did called InvisibleKillers.We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t goover), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you haveto be at Aspen at noon {I was invited too) -- so I could take you if you like.I realize that this may be too much. -- but in these times, I think it's important to get smart commentaryand analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to themillions you are already reaching. The producers are also able to provide car and driver (b)( 4)(b) (4)Hope this might work my frie nd. I may send a short form of this to your cell phone.Call me if you want to chat, either of you, ata II best, STEVETheHlll.comSteve ClemonsEditor at Large, The Hill1625 K Street NW, Suite 900Washington, DC 20006Tel: .,.1.202.628.8500Cell: (6)Email: SClemons@TheHill.comFollow me on Twitter @SCClemons-----(b) (6).NIH-002165From:Sent:To:(b)(6)Wed, 5 Feb 2020 10:33:15 -0500Conrad, Patricia (NIH/NIAID) [E]Subject: Fwd: NTV Broadcasting Interview RequestFYIBegin forwarded message:From: Cecpep6eKOXBa ,1Kl)u-MypaTK apaxaHOBH<qH Seferbekov@ntv.ru>Date: Fehmary 5, 2020 at I 0:21: 15 AM EST -------~= To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6>lSubject: NTV Broadcasting Interview RequestMr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcastingcompany .We would like to film a brief interview with you about coronavirus, and different hypothesesabout its appearance. We want to solve the problem with mass disinformation about thisvirus, and need a professional opinion.Will it be possible to do th is at 6th , or 7th of February?Best regards,Seferbekov MuratNTV Broadcasting CompanyNIH-002170From :Sent :To:Fauci, Anthony (NIH/NIAI0) [E)Wed, 5 Feb 2020 14:36:13 +0000Conrad, Patricia (NIH/NIAID) [ElSubj ect : FW: Interview request by BBC ChineseAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Tsung-Hsien Lee <zach.lee@bbc.co.uk>Sent : Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El-- ----------"-"=-"-"-(b")(6-) :-= Subject: Interview request by BBC ChineseDear Dr Anthony s Fauci,This is Zachary from BBC Chinese.I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirusin different countries .Most of the countries told the public where the people evacuated from Wuhan reside for quara ntineand some drew local's protests . They expressed concern over close vicin ity and some even went toprotest in these places.Others like Taiwan, the authority decided to keep the quarantine location confidential. The reason is toavoid unnecessary worr isome and let people rest wel l.I would like to have an interview with you by e-mail or Skype phone with you to give some insights orcomments on this issue.If you could be quoted, the questions are as below1. Why does the government tell the public the quarantine location? Is it necessary? Or why not?NIH-002171NIH-0021722. Many residents protested because they don't want the quarantine Center for Coronavirus in theirneighborhood . Do they need to worry about it?3. What is your suggestion regarding the location of quarantine those people from Wuhan. And wh atis essenti al for Quarantin e Center for Coronaviru s?Thank you very much for your time .Zachary LeeBBC ChineseFrom:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 1 Mar 2020 01:17:02 +0000Harper, Jill (NIH/N IAID) [E]Subject: RE: Approps TA: DOE Reimbu rsement for Coronavirus Super ComputingAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)(b) (5)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6)Sent: Saturday, February 29, 2020 9:43 AM To: Fauci, Anthony (NIH/NIAID) [E]-" -"-:-"-:-====-(=b=)(=6=J>- ~-~~ Cc: Haskins, Me linda {NIH/NIAID) [E]- --------- (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronavirus Super ComputingTony,Thanks,JillFrom: "Harper, Jill (NIH/NIAID) [E)" --------- (b)(6) Date: Friday, February 28, 2020 at 5:33:38 PMNIH-001137(b) (5)To: "Fauci, Anthony (NIH/NIA ID) [El" _______(b ) (6_).>Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super ComputingTony, I will call you about this in a minuteFrom: "Haskins, Melinda (NIH/NIAID) [E]" (b)(6)Date : Friday, February 28, 2020 at 5:24:43 PM -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)>Cc: "NIAID OCGR Leg" <NIAIDOCGRLeg@mail.nih.gov>, "La Montagne, Karen (NIH/OD) [El"(b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~=S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)"-------- CbH6)",S hapiro, Neil (NIH/OD) [El" CbH Subject : Re: Approps TA: (b)(S)Sent from my iPhoneOn Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El ----------(b)( > wrote:Hi Melinda,Would you let me know what you all think of this language?Thanks.MMFrom: Friedel, Laura (Appropriations) ------------ (b)( > Sent: Friday, February 28, 2020 5:13 PM -------~= To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle(NIH/OD) (E] (b)(6)Subject: RE: DOE Reimbursement for Coronavirus Super ComputingAny progress on this Michelle? Here is language that I'm thinking of.For an additional amount for "National Institute of Allergy and InfectiousDiseases", to prevent, prepare for, and respond to SARS-CoV-2, a virus sb·ainmutat ing therefrom ("coronavirus"), or other emerging or reemerging infect iousdisease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lableNIH-001138(b) (5)until September 30, 2024: [Provided. That up to $99.500.000 of such amounts maybe tran sferred to the Depai1rnent of Energy to provide sup po1t and access toscient ific user fac ilities , includin g equ ipm ent, ena bling techn olog ies, and personne lassocia ted with the opernt ions of those scienti fic user fac ilities:]Laura FriedelMajority ClerkCommittee on AppropriationsSubcommittee on Labor, HHS and Education136 Dirksen Senate Office BuildingWashington, DC 20510(b)(6)From: Friedel, Laura (Appropriations)Sent: Friday, February 28, 2020 3:13 PMTo: Haskins, Melinda (NIH/NIA ID) [E]--------=- C"Hb"'""'>; Michelle Mitchell(b)(6)Subje ct: DOE Reimbursement for Coronavirus Super ComputingHi,Dept. of Energy is looking for $99.5 million. They are concerned that NIH wil l use theirsuper computers for coronavirus (which NIH doesn't pay for) and displace payingcustomers. What is the expectation that NIH will need to use DOE super computers? Wewould include addit ional funds (please make sure TF knows I would not take his funds andgive to DOE), but this seems extremely high to me and I was trying to understand the needfrom your perspective for these super computers . Happy to jump on the phone if that iseasier, but need this as fast as you can get it to me please- within the next hour or so.Language is below . Thank you !Sec._. (a) Funds appropriated in this title may be made available torestore amounts , either directly or through reimbursement , for obligations incurredby agencies of the Department of Health and Hum an Services for the purpo sesprovided herein pr ior to the date of enactment of this Act. This subsection shall notapply to obligations incurred by the Infectious Diseases Rapid Response ReserveFund .(b) Funds appropriated in this title [may /shall] be used when [awarding /toaward] grants and cooperative agreements in fiscal yea r 2020 to reimburse State orlocal costs incurred for the purposes provided herein after January 20, 2020 , andprior to the issuance of such awards.[(c) Funds appropriated in this title shall be transferred to other federalagenc ies for costs related to medical screening for coronavirus including any costsNIH-001139incurred through a grant, coopera tive agreement, other transaction, or contract and,once transferred, may be used to reimbur se obligation s incurred for such purpo sesprior to enactme nt of this Act.]( d) U_p to $99,500,000 of the funds a ro~riated in th is title may betransferred to the Depa rtment of Energy to_provide su1;mort and access toscient ific user facilit ies, includin g e uipm ent, enabling technologies, andpersonnel associated with the o erat ions of those scientific user facilities.( e) If any funds have been reprogrammed or trans ferred from anappropriation , as described in the notific ation submitt ed by the Secretary to theCommittees on Appropr ia tions of the House of Repr ese ntatives and the Senate onFebruary 2, 2020, prior to the date of enactment of this Act, such amounts shall berepro grammed or transferred back to that appropriation within 45 days of the date ofenactment of this Act.Laura FriedelMaj ority ClerkCommittee on AppropriationsSubcommittee on Labor, HHS and Education136 Dirksen Senate Office BuildingWashington, DC 20510(b)(6)NIH-001140From: Fauci, Anthony (NIH/NIAIO) [E)Sent:To:Subject:Thu, 13 Feb 2020 22:36:17 +0000Messonnier, Nancy (CDC/DDID/NCIRD/0D)RE: NASNancy:The official USG group will be convened by NAS. Bob Kadlec is the person withdirect knowledge of that. In addition, there is an ad hoc group informally led byJeremy Farrar of Wellcome Trust. This group has about 15 people, all of whomare highly respected scientists, mostly evolutionary biologists who are conveningby e-mail and conference calls (I have been on 2 of these calls since Jeremyinvited me) to look at all of the bat, pangolin and human coronavirus sequencesto try and determine the evolutionary origin. This is not my area of expertise andso I have backed off and am leaving it all to Jeremy.Best,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >Sent : Thursday, February 13, 2020 5:28 PM ------ ..-.-,= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)>Subject: RE: NASThanks. Is someone conven ing them?From: Fauci, Anthony (NIH/NIAID) [E] ______ (b_H_6)Sent: Thursday, February 13, 2020 5:07 PMNIH-001920To: Messonnier, Nancy (CDC/0010/NCIRD/OD) ------ (b)(6)Subject: RE: NASNancy:It is not a report. It is a letter from NAS to OSTP saying that it is important tobring together a group of experts to study the evolutionary origin the COVID19. Iam attaching it here. I have no idea if it has been widely distributed and so pleasekeep it internal.Best,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone Cb()6 )FAX: (301 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) ------- (b)(6) Sent: Thursda y, February 13, 2020 1:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)(6) Subject: NASEither you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2.Thanks.NancyNIH-001921--From:Sent:To:Subject:Attachments:Nancy:Fauci, Anthony (NIH/NIAIO) [E)Thu, 13 Feb 2020 22:06:37 +0000Messonnier, Nancy (CDC/DDID/NCIRD/OD)RE: NASNASEM Response to OSTP re Coronavirus_February 6 2020.pdfIt is not a report. It is a letter from NAS to OSTP saying that it is important tobring together a group of experts to study the evolutionary origin the COVID19. Iam attaching it here. I have no idea if it has been widely distributed and so pleasekeep it internal.Best,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Messonnier, Nancy (CDC/0010/NCIRD/OD) CbH >Sent: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] CbH6)>Subject: NASEither you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2.Thanks.NancyNIH-001922--From: Fauci, Anthony (NIH/NIAIO) [E)Sent: Thu, 6 Feb 202015:21:22 +0000To: Billet, Courtney (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer(NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E]Subject: RE: Redfield/Fauci nCoV op-edAttachments: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docxHere it is.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It shou ld not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [E] (b)(6)Sent : Wednesday, February 5, 2020- -3:-43- -PM- ::;..,..-,= To: Fauci, Anthony (NIH/NIAID) [E] ~=======-~= Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E)(b)(6J>; Routh, Jennifer (NIH/NIAID) [E) --------- (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)>Subject: FW: Redfield/Fauci nCoV op-edHere is the op-ed as cleared by WH.Any issues with this?(b) (5)From: Brennan, Patrick (OS/ASPA)Sent : Wednesday, February 5, 2020 3:39 PM(b)(6)-------~~ To: Routh,Jennifer (NIH/NIAID) [E]- -------- (b)(6); Lepore, Loretta (CDC/0D/OCS) (b )( 6)Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC)(b)(6J>; Bonds, Michelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID)':["E:::)-====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan,Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6);NIH-002108Stecker, Judy ( OS/IOS) CbH6J; Murphy, Ryan (OS/ ASPA) CbH6JPratt , Michael (OS/ASPA) (b)(6)0akley, Caitlin 8. (OS/ASPA)(b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] ========,~';5""=-- (b )( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID)~[E~l =====~ (b~)(=6)Subject: RE: Redfield/Fauci nCoV op-edAttached is a tracked changes version and a clean version of what cleared the WH - they had a fewsentences they would like to be added (wh ich, in the tracekd changes version, I have added commentsto explain who suggested it and in some cases why), but almost all of these edits are non-substantive.Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all aregood to pitch this as you wish - (b) (5)From: Routh, Jenn ifer (NIH/NIAID) [E] (b)(6)Sent : Sunday, February 2, 2020 6:11 -P-M-~ ~ To : Lepore, Loretta (CDC/OD/OCS) <j (b)( ~ >Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC)------(b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet,Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS)CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>S; tecker, Judy (OS/IOS) :::======~=-'- -c-c= --~--~====(b):(6:)>:;! M,_ur.p:hy,,_ R_y_an~ (O~S/A SPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill(HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John(NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6)Subject: RE: Redfield/Fauci nCoV op-edAll - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci.Thanks,JenJennifer Routh [E]News and Science Writing BranchOffice of Communi cations and Government Rela tionsNational Institute of Allergy and Infectio us Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda, MD 20892Direct: Cb()Disc laimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not beused by anyone who is not the original intended recipient. If you have rece ived th is e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. The National Institute or Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives.From: Lepore, Loretta (CDC/OD/OCS) ____ C_>b_C_6 )Sent : Sunday, February 2, 2020 2:39 PMNIH-002109To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds,Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Courtney (NIH/NIAID} [ElCc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S};Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA};Myles, Renate (NIH/OD} [E]Subject : RE: Redfield/Fauci nCoV op-edGood afternoon all,I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ourcolleagues at NIH.Please reach out with any quest ions.Best,LorettaFrom: Fine, Amanda (NIH/OD) [El- ------- (b)(6) Sent: Friday, January 31, 2020 6:36- P-M- --,.= To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA}(b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia"(:N""::l"'H.'"/"'::N''":'.I"A~'.l"-D:-}:-:[~E:]-::::::===-,:_-~ (;ba~=-c,-6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>;Lepore, Loretta (CDC/00/0CS} (b)(6)>Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS)(b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b")"('=6); Murphy, Ryan (OS/ASPA}(b)(6); Pratt, Michael (OS/ASPA} (b)(6); Oakley, Caitl in 8.7( 0:-S::/- :-A:-S:-P::A-:--}: --.======;...._--= (b")' "("6")">'; Hall, BiI I ( HHS/A SPA} (b) (6)>; Myles, Renate _____ _,,(NIH/OD) [E] ______ C_>bC6)Subject: RE: Redfie ld/Fauci nCoV op-ed+ Renate Myles for awarenessFrom: Galatas, Kate (CDC/OD/OADC} ------ (b)(6) Sent : Friday, January 31, 2020 6:34 PM ------~~ To: Brennan, Patrick (OS/ASPA} (b)(6) 1>; Bonds, Michelle E. (CDC/0D/OADC)(b)(6); Fine, Amanda "(:'~N:I-H::-/-O:~- D:}- :[:E:--] :--:=====...:....__, (ab~-~,<-6)>;C onrad, Patricia (NIH/N IAID) [E]=====:=;..--=- (b.),(.:=6, )>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1>; Lepore, Loretta (CDC/00/0CS} (b)(6)Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS),..:..!::====::::::_:_~(b)(6)>; Stecker, Judy (OS/10S} (b)(6); Murphy, Ryan (OS/ASPA}(b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B.(05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6)Subject: Re: Redfield/Fauc i nCoV op-edHi, Patrick -We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH commscan move thru with thei r editing/revisions.NIH-002110let me know if that sounds OK. We will likely not have a cleared version out of CDC until late Saturdayat the earliest.Take care,KateGet Out look for iOSFrom: Brennan, Patrick (OS/ASPA) (b)(6)Sent : Friday, January 31, 2020 5:31:46 PMTo: Bonds, Michelle E. (CDC/0D/OADC)_ ___ (~b)- (6=) >; Fine, Amanda (NIH/OD) [El(b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet, Courtney(NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)>Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS)(b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA)(b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B.":"::":--:-'.:-:-::--:-:-::=====::....-~~(OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate(CDC/OD/OADC) (b)( >Subject : Redfield/Fauci nCoV op-edCDC and NIH folks,Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding thereasons/thinking behind the policy announced today. I assume the right building blocks for it would bethe remarks they made today- which I believe you all should have the copy/notes for? I have theSecretary's, which we'll be sending around/post ing shortly and I'll make sure to re-up it here so you allhave it.It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!)Please let me know how I can help wi th t his.Best,PatrickPatrick BrennanDirector of SpeechwritingDepartmen t of Health and Hum an ServicesOffice: (b) (6) I Cell (b) (Predecisional/deliberative communicationNIH-002111From:Sent :To :Subj ect :FYIAnthony S. Fauci, MDDirecto rFauci, Anthony (NIH/NIAI0) [E)Tue, 11 Feb 2020 12:54:11 +0000(b)(6)FW: Following Up If We can Be of Any AssistanceNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: Cb) (6)FAX: (301 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Kadlec, Robert (OS/ASPR/1O) --------- (b)( >Sent: Tuesday, February 11, 2020 7:28 AMTo: CbHCc: (b)(6) Elvander, Erika (OS/OGA) CbH6); Lamana,Joseph (OS/ASPR/E_M_ MO..). ;_-=====~:;;;---:------:----:-----:---:-- Cb)( ; Disbrow, Gary;(.O.S./. A._S..P .R :/ B;.__A..R_ .D A.). :.!:=~"""'.'.'"-~Cb-H.6-); -Y.e-s-k-ey, Kevin (OS/ASPR/1O) ---------(b)( >; Fauci, Anthony (NIH/NIAID) [E] ---------(b)(6) Subject: RE: Following Up If We can Be of Any AssistanceDear Dr. Suzuki we heard from Jun the news that your Prime Minister gave app roval fo r t hedeplo ym ent of our team. We are moving expediti ous ly to get them th ere to assist. In light ofthe situ at ion and t he increasing numbers of cases on the ship, CbH5>NIH-001970(b) (5)Again, we are grateful and excited that we have the opportunity to work together.Kan pailBobFrom: Kadlec, Robert /OS/ ASPR/10)Sent: Monday, February 10, 2020 8:14 PMTo: (b)(6)Cc: (b)(6); Elvander, Erika (OS/OGA)_ .......=====::"C"b"H6"); '~La~m:a-n-a, Joseph (HHS/ASPR/OEM) Cb)(6)(b)(6)Subject: Following Up If We can Be of Any AssistanceDear Dr. Suzuki -I hope this finds you I good health and expect that you are deeply involved in the events ofcoronavirus in your region . I understand from various communications with the MHLW that isconsidering ending the quarantine early and releasing passengers from the Diamond Princess,especially those who are 80 years of age or older. Given the media reports and publicperception there is pressure to do th is. However, as medical experts, you and I both know thatdays 3 - 8 are within the norma l incubation period and these new positives do not likelyrepresent shipboard transmission. As such, HHS is willing to coordinate U.S. medical expertswho can engage with English language media explaining and reassuring the passengers, crew,and public.Regarding support for the quarant ine, ASPR is ready to deploy a team of 3-5 people quickly, andas many 12 people to Japan to support as suggested in the previous call. If we can assist youand your team in managing the Americans currently in quarantine please let me know. If thereis other support do let me know and ASPR will work to assist. As we've talked for the past 18months about such a scenario, this may not be the one we envisioned, but it is a perfect case aswe can clearly ident ify the Americans, they are in a contained area. Our mutual efforts andplanning have paid unexpected dividends.I am available to discuss via teleconference at your convenience. I am grateful fo r all MHLWhas done to support this complicated response on top of your work supporting repatriation anddomestic monitoring of your own citizens. We are grateful for Dr. Sugihara's herculeaninformation sharing efforts and the rest of your MHLW team support during this event; itNIH-001971NIH-001972validates of the importance of our ongoing liaison program and the long term benefits of ourmutual commitment to each other's public health securityPlease remain well and I look forward to see you again soon.Best wishes and warm regards.Dr Bob KadlecASPRFrom:Sent:To:Fauci, Anthony (NIH/NIAID) [E]Mon, 10 Feb 2020 18:43:59 +0000Brennan, Patrick (OS/ASPA)Cc:Subject:Hall, Bill (HHS/ASPA);Conrad, Patricia (NIH/NIAID) [E]RE: Draft of emailAttachments: 2 10 20 email - with Fauci edits.docxHere is the document with my tracked changes. GAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Brennan, Patrick (OS/ ASPA) ---------- (b)(6)Sent: Monday, February 10, 2020 1:26 PM --------=-c-= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >Cc: Hall, Bill (HHS/ASPA) <Bill.Hall@HHS.GOV>Subject: Draft of emailDr. Fauci - below and in the attached is our proposed draft response, and then Cuccinelli'semail text below for context. We're waiting on a potential detail/point or two from ASPR thatmay help flesh it out a bit but we'll see if we actually need it. Thank you !<< File: 2 10 20 email.docx >>Draft HHS responseFellow task for ce members,Thanks for your message, Ken, and I look fo rw ard to ou r di scussion tod ay.NIH-001994(b) (5)Looking forward to discussing more later today.KenTo mv fellow task force members(b) (5)NIH-001995(b) (5)NIH-001996I look forward to speaking with you all again this afternoon.Patrick BrennanDirector of Speechwrit ingDepartment of Health and Human ServicesOff ice: (b)(6) I Cell: (b)(6)NIH-001997From:Sent :To:Subject:Anthony S. Fauci , MDDirectorFauci, Anthony (NIH/NIAIO) [ElSun, 9 Feb 2020 23:54:27 +0000(b)(6)FW: WHO advance team on coronavirus on way to China - Tedros tweetNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Grigsby, Garrett (HHS/OS/OGA)Sent : Sunday, February 9, 2020 6:35 PM(b) (6)•>To: Fauci, Anthony (NIH/NIAID) [El --------------=---:-=(b:)-(i ; Harrison, Brian (HHS/10S) (b )( 6)Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA)"':'-"--:----:-(:b):( =·>=; Z=eb=ley~, K yle (HHS/0S/OGA) ".-:======(b=)(6)~ R=ed field, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)((FDA/OC) --------- (b)(6)>; Bright, Rick (OS/ASPR/BARDA) --------- Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweetDr F,From: Fauci, Anthony (NIH/N IAID) [E] -------- (b) ~ > Sent: Sunday, February 9, 2020 6:24 PMTo: Grigsby, Garrett (HHS/OS/OGA)------- .C-..Hb..,=6)>; Harrison, Brian (HHS/105)(b)(6j>NIH-0020 14(b) (5)Cc: Kerr, Lawrence ( HHS/0S/OGA) Cb() >; Elvander, Erika (OS/OGA)(b)(6); Zebley, Kyle (HHS/0S/OGA)"(:C -::-D:~C:/"0':::""D.::":)';:=' ==='c (b~)(~ >; Kadlec, Robert (O S/A SPR/I0)~======C~b~C) >; Redfield, Robert R. (b)(6)>; Abram , Anna( FDA/OC)- -------- (b)( 6)>; Bright, Rick ( OS/A SPR/BARDA) -------- (b)(6) Subjec t: RE; WHO advance team on coronavirus on way to China - Tedros tweetAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail : (b)(6)(b) (5)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Grigsby, Garrett (HHS/0S/OGA)Sent : Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6)(b)(6)--:-::.::=========!~=Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6; JElvander, Erika (OS/OGA)(b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>R;e dfield, Robert R.( C~D:-C:-/:0-:::-D:-:):: -:.===== (=b)s,:(:6~; ); Fauci, Anthony ( NIH /N IAID) 7[ E::]---.:::=====~ (b~)(=6)>; KadI e c, Robert(OS/ASPR/10) (b)(6)>; Abram, Anna (FDA/OC) (b)(6)>; Bright,Rick (OS/A SPR"/"-B:AR_D_A~)--======~ (=b)-(~6)Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweetBrian - more clarity from "the horse's mouth" on this advance trip ... see below .From: Grigsby, Garrett (HHS/OS/OGA)Sent : Sunday, February 9, 2020 6:01 PM --------=-cc-c= To: SCHWARTLANDERB, ernhard F. (b)(6)Cc: SIMONSON, Stewart (b)(6)>Subject : RE: WHO advance team on coronavirus on way to China - Tedros tweetMany thanks, Bernard! I know I'll be asked, so I will pass your email up thechain ...NIH-0020 15Take care and thanks again!From: SCHWARTLANDERB, ernhard F.- --------- (b)(6)Sent: Sunday, February 9, 2020 5:59 PMTo: Grigsby, Garrett (HHS/OS/OGA)------- -= (b=H=6)>Cc: SIMONSON, Stewart (b) (6)Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweetHi Garrett,We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizingthe TOR and composition of the joint WHO - China mission. As you are much aware, the US has given usa number of names who will be able and wi lling to jo in such a mission. We have received similarproposals from other countries and will now match the "long list" of experts with the required specificexpertise.We are hoping to have more clarity over the coming days and will obviously keep you in the loop. Theoverall number will be kept at a level to make sure that the team is fully operational.With my warmest wishesBernhardDr Bernhard SchwartlanderChef de CabinetWorld Health OrganizationOn 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA)wrote:Bernard,Hope you had a good weekend.(b) (6)> ---------I'm reaching out to get more clarity on the WHO experts team issue -please see article below . I've heard everything from an advance groupof one or two individuals to 15 people discussed in the article. I haven'theard any word about US people, and I was just with Dr Redfield latethis afternoon and he was in the dark too.NIH-002016Any additional information wil l be deeply appreciated.Thanks!From: Kerr, Lawrence (HHS/OS/OGA) (b)( >Sent: Sunday, February 9, 2020 5:03 PM -------- == To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle(HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA)----------(b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweetFebruary 9, 2020 / 4:01 PM/ Updated an hour agoUPDATE 1-WHO advance team oncoronavirus on way to China - TedrostweetStephanie NebehayBy Stephanie NebehayGENEVA, Feb 9 (Reuters)• An advance team of international experts led by the WorldHealth Organization (WHO) has left for Beijing to help invest igate China's coronav irusepidemic, the Geneva-based agency said on Sunday.WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing for talkswith President Xi Jinping and Chinese ministers in late January, returned with anagreement on sending an international mission.But it has taken nearly two weeks to get the government 's green light on its composition,which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, aCanadian epidemiologist and emergencies expert, was heading it."I've just been at the airport seeing off members of an advance team for the @WHO-led#2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran ofpast public health emergencies," Tedros said in a tweet from Geneva.Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with topChinese health officials, told Reuters last week that they were discussing a list of expertswith China."Because it is a joint mission, they need to be on board, it's not just an international groupgoing there. We have about 15 people," said Briand, director of Global Infectious HazardPreparedness at WHO.China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing thenumber killed globally by the SARS epidemic, as authorities made plans for millions ofpeople returning to work after an extended Lunar New Year break.The virus , which has spread to two dozen countries, has killed some 2% of more than37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show.The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinesecentral government imposed a lockdown on 60 million people in Hubei province and itscapital Wuhan, epicentre of the virus that emerged in December in a seafood marke t.NIH-002017NIH-002018Tedros said on Saturday that he hoped the team would include experts from the U.S.Centers for Disease Control (CDC)."It has to be meaningful on the ground," Lawrence Gostin, professor of global health law atGeorgetown Law, said in an interview in Geneva this week.Gostin called for a "genuine partnership with transparent flows of information andaccountability for the response", adding that there should be a strong CDC presence."CDC has got no peer in terms of its experience and technical expertise in dealing withinternational outbreaks," he said."But the other benefit is the smart diplomacy, what it could signal is that despite all of ourdifferences in ideology, trade , politics, that when faced with a common threat to humanity,we come together as a human community to tackle it," Gostin said.Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten DonovanOur Standards:The Thomson Reuters Trust Prin cip les.From: Fauci, Anthony (NIH/NIAID) [E)Sent : Fri, 7 Feb 2020 03:55:22 +0000To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence{NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [ElCc: Shaya, Cecile (NIH/OD) [ElSubject: RE: Coronavirus - HHS Supplemental Table - Close Hold(b) (5)From: Shapiro, Neil {NIH/OD) [El (b)(6)Sen t: Thursday, February 6, 2020 8:08 PM -----~ = To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El(b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne"":"----:----:-:-:-::-====::!.....:.--~~(NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6)Cc: Shaya, Cecile (NIH/OD) [El (b)(6)Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold(b) (5)NeilFrom: Collins, Francis (NIH/OD) [El (b)(6)Se nt: Thursday, February 6, 2020 4:59 PMTo: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {NIH/OD) [El(b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne"":"----:-:-:-:-:-:-::.:====:::::..;,-- ~=(NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6)Cc: Shaya, Cecile (NIH/OD) [El (b)(6)>Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold(b)(S)FCFrom: Shapiro, Neil {NIH/OD) [E] ------- (b)(6)>Sent: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El ------- (b-)(-6-);- -T-a=ba k, Lawrence {NIH/OD) [E](b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~(NIH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc:Shaya,Ce .c..:i l-e:-- (:-N:~-IH~/:0---0::::7-) ':["-E:-:l ::=-.===--..;_ ("b")-'(:6--)= -Subject : FW: Coronavirus - HHS Supplemental Table - Close HoldImpo rt ance: HighNIH-002087ASFR provided the pdf attachment and the explanation below. They emphasized on the phone too thatthis is very close hold . Cb) (5i(b) (5)NeilFrom: Cabezas, Miriam (HHS/ASFR) ----------- Sent: Thursday, February 6, 2020 2:32 PM ----~~ To: Kelly, Alison (CDC/OCOO/OFR/OA) (b)(6)>; Berger, Sherri (CDC/OCOO/O0)CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>S; haya, Cecile (NIH/OD) [E] =====~ Cb~>; Peti llo, Jay (OS/ASP':R"'/ 7M-:-F::H--::-C-~:) -====~ CbH6J>D;u bay, Johanna( OS/ ASPR/M FHC) (b)(6)Cc: Goyle, Suraj (OS/ASFR) (b)(6)>; Falisi, Angela (OS/ASFR)White, RaeShawn (OS/ASFR) CbH6J>C;o rmier, Justin (HHS/ASFR)(b) ( >Subject: Coronavirus - HHS Supplemental Table - Close HoldInformation in this email is close hold.Good afternoon -(b) (6)>;Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. Wewant to make sure you have awareness of the activities that are identified across these three agencies.Let us know if you have any questions . This information should not be shared broadly.MiriamNIH-002088From: Fauci, Anthony (NIH/NIAIO) [ElSent : Fri, 7 Feb 2020 03:38:07 +0000To: Marston, Hilary (NIH/NIAID) [E]Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - MinisterMa of China Response Letter - 00430215Please take care of this on my behalf. Thanks.From: Marston , Hilary (NIH/NIAID) [E] (b)(6)Se nt: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E]< (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert{NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >;McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E]------- CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGR Correspondence <NIAIDOCGRCorrespondence@mail.nih.gov>; Gilles, Sharon(NIH/NIAID) [E) (b)(6) Fauci, Anthony (NIH/N IAID) [E) (b)(6);Conrad, Patricia (NIH/NIAID) [E) (b)( >Subject : RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of ChinaResponse Letter - 00430215From: Harris, Kara (NIH/NIAID) [El CbH6)>Sen t: Thursday, February 6, 2020 3:00 PMTo: Handley, Gray (NIH/NIAID) [E]---------=- (b")"("=6) Marston, Hilary (NIH/NIAID) [El(b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert(NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)(McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El--------- (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGR Correspondence <NIAIDOCGRCorrespondence@mail.nih.gov>; Gilles, Sharon(NIH/NIAID) [E] (b)(6)NIH-002093(b) (5)Subject: FW: ** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of ChinaResponse Letter - 00430215Importance: HighAll-Please see the note below from Exec Sec. Please provide any comments to NIAID OCGRCorrespondence by 3:30 p.m. Please note - Exec Sec is looking for show-stopping comments only.Thank you,KaraFrom: Malliou, Ekaterini (OS/10S) ---------- (b)(6)> Sent: Thursday, February 6, 2020 2:25 PM ---------=-c-=, To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS)(b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC)--~-.-:::====:!(.b-)(6-) Chan..g;,~; W. :il.liam {HHS/OGC) (b)(6)>; Barry, Daniel J(HHS/OGC)" ~' ~-.-:::==== (b=)(=6)::>..;: ..sh_u.y:.;,,, .B~ryan (OS/ASPR/10) (b)(6); Bird,Catherine (05/0GC) (b)(6) OS OGC-10 <Contro1Desk.OGCl0@hhs.gov>; ASPR ExecSec (OS/ASPR)< ASPRExecSec@hh.gsov>Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S)(b)(6) >; Hawk~i-ns-,-J:a- m- ar- (:-H:-H:--S:-/:0".:S")": -:.":'=.=:;.....::;._...:,__...:...~ (b:).,.(,6-=);, Horska, Katerina(HHS/IOS) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6);Zebley, Kyle (HHS/0S/OGA)- ------- (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] (b)(6)Subject : Clearance Due 6pm (2/6): **Time -Sensitive** Coronavirus - Min ister Ma of China ResponseLetter - 004302 15Please find attached for your clearance a response to Minister Ma's letter to the Secretary, and arecent conversation with him. (b) (5)Please note that the Secretary has already reviewed and edited the attached responseWe appreciate your expedited review and clearance by 6pm today, 2/6.Thank you,Kat****************************************Ekaterini (Kat) Malliou , DrPH, MPHSenior Policy Coordinator[mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices200 Independence Ave SW, Suite 619H, Washington, DC 20201, USATel: (b)(6) Cell: (b)( , Email: (b)(6)NIH-002094From:Sent :To:Cc:(b)(6)Thu, 6 Feb 2020 18:56:07 -0500Conrad, Patricia (NIH/NIAID) [E)Billet, Courtney (NIH/NIAID) [ElSubject: Re: FROM CAITLIN OAKLEY -Atlantic reporter respondedPlease schedule call for tomorrow.On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/NIAID) [E](b)(6) wrote: ----------See below -the reporter responded to Caitlyn - not Courtney- he canspeak today or tomo rrow. Do you want to call tonight or have meschedule for tomorrow?Tomorrow is quite full but can make it happen ... let me knowYes, happy to talk today or tomorrow.I'm at (b) (6)If Dr. Fauci is avai lable, that would be great.Best,Peter NicholasPatr icia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Inf ect ious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The information in this e-mail and any of its attachments is confidential and may contain sensitive information. ItNIH-002101should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in errorplease inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergyand Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and notexpress ly made on behalf of the NIAID by one of its representatives .From: Oakley, Caitlin B. (OS/ASPA) ~- --------- (b)(6)> Sent: Thursday, February 6, 2020 4:12 PM ------ ~= To: Billet, Courtney (NIH/N IAID) [El (b)( >; Conrad, Patricia (NIH/NIAID) _______ _,[El (b) (6)Subject: FW: follow up re: Coronavirus storyCaitlin B. OakleyDeputy Assis tant Secretary, Nat ional SpokespersonOffice of the Assistant Secretary for Public AffairsU.S. Department of Health and Human Services(b)(6))From: Peter Nicholas <pnicho las@t heat lant ic.com>Sent: Thursday, February 6, 2020 3:00 PM -------- -=---= To: Oakley, Caitlin B. {OS/ASPA) ----------(bH > Subject: Re: follow up re: Coronavirus storyHi,Yes, happy to talk today or tomorrow.I'm at (b)(6). If Dr. Fauci is available, that would be great.Best,PeterOn Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA)(b)(6) wrote: ----------- F o 11o wing up on this .... does today work?And I know Dr. Fauci's office is trying to get in contact as well. He's a memberof the taskforce. Can we make this happen?Caitlin B. OakleyDeputy Assistant Secretary, National SpokespersonOffice of the Assistant Secretary for Public AffairsU.S. Department of Health and Human Services(b)(6)NIH-002102From: Oakley, Caitlin B. (OS/ASPA)Sent: Wednesday , February 5, 2020 3:55 PMTo: pnicho las@theat lant ic.comCc: Hall, Bill (HHS/ASPA) ____ C_b)_(6_) >Subject: follow up re: Coronavirus storyPeter- Thanks for the chat yesterday. Have a few folks that I'd like to get you onthe phone with about your piece. Would you have time to chat with Bill Hall and Ilater today?And when is your deadline for the piece?Talk soon,Caitlin B. OakleyDeputy Assistant Secretary, Natio nal Spokesper sonOffice of the Assistant Secretary for Public AffairsU.S. Department of Health and Human Services(b)(NIH-002103From: Fauci, Anthony (NIH/NIAIO) [E)Sent: Thu, 6 Feb 202015:21:22 +0000To: Billet, Courtney (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer(NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E]Subject: RE: Redfield/Fauci nCoV op-edAttachments: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docxHere it is.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It shou ld not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [E] (b)(6)Sent : Wednesday, February 5, 2020- -3:-43- -PM- ::;..,..-,= To: Fauci, Anthony (NIH/NIAID) [E] ~=======-~= Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E)(b)(6J>; Routh, Jennifer (NIH/NIAID) [E) --------- (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)>Subject: FW: Redfield/Fauci nCoV op-edHere is the op-ed as cleared by WH.Any issues with this?(b) (5)From: Brennan, Patrick (OS/ASPA)Sent : Wednesday, February 5, 2020 3:39 PM(b)(6)-------~~ To: Routh,Jennifer (NIH/NIAID) [E]- -------- (b)(6); Lepore, Loretta (CDC/0D/OCS) (b )( 6)Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC)(b)(6J>; Bonds, Michelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID)':["E:::)-====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan,Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6);NIH-002108Stecker, Judy ( OS/IOS) CbH6J; Murphy, Ryan (OS/ ASPA) CbH6JPratt , Michael (OS/ASPA) (b)(6)0akley, Caitlin 8. (OS/ASPA)(b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] ========,~';5""=-- (b )( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID)~[E~l =====~ (b~)(=6)Subject: RE: Redfield/Fauci nCoV op-edAttached is a tracked changes version and a clean version of what cleared the WH - they had a fewsentences they would like to be added (wh ich, in the tracekd changes version, I have added commentsto explain who suggested it and in some cases why), but almost all of these edits are non-substantive.Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all aregood to pitch this as you wish - (b) (5)From: Routh, Jenn ifer (NIH/NIAID) [E] (b)(6)Sent : Sunday, February 2, 2020 6:11 -P-M-~ ~ To : Lepore, Loretta (CDC/OD/OCS) <j (b)( ~ >Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC)------(b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet,Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS)CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>S; tecker, Judy (OS/IOS) :::======~=-'- -c-c= --~--~====(b):(6:)>:;! M,_ur.p:hy,,_ R_y_an~ (O~S/A SPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill(HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John(NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6)Subject: RE: Redfield/Fauci nCoV op-edAll - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci.Thanks,JenJennifer Routh [E]News and Science Writing BranchOffice of Communi cations and Government Rela tionsNational Institute of Allergy and Infectio us Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda, MD 20892Direct: Cb()Disc laimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not beused by anyone who is not the original intended recipient. If you have rece ived th is e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. The National Institute or Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives.From: Lepore, Loretta (CDC/OD/OCS) ____ C_>b_C_6 )Sent : Sunday, February 2, 2020 2:39 PMNIH-002109To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds,Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Courtney (NIH/NIAID} [ElCc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S};Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA};Myles, Renate (NIH/OD} [E]Subject : RE: Redfield/Fauci nCoV op-edGood afternoon all,I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ourcolleagues at NIH.Please reach out with any quest ions.Best,LorettaFrom: Fine, Amanda (NIH/OD) [El- ------- (b)(6) Sent: Friday, January 31, 2020 6:36- P-M- --,.= To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA}(b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia"(:N""::l"'H.'"/"'::N''":'.I"A~'.l"-D:-}:-:[~E:]-::::::===-,:_-~ (;ba~=-c,-6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>;Lepore, Loretta (CDC/00/0CS} (b)(6)>Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS)(b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b")"('=6); Murphy, Ryan (OS/ASPA}(b)(6); Pratt, Michael (OS/ASPA} (b)(6); Oakley, Caitl in 8.7( 0:-S::/- :-A:-S:-P::A-:--}: --.======;...._--= (b")' "("6")">'; Hall, BiI I ( HHS/A SPA} (b) (6)>; Myles, Renate _____ _,,(NIH/OD) [E] ______ C_>bC6)Subject: RE: Redfie ld/Fauci nCoV op-ed+ Renate Myles for awarenessFrom: Galatas, Kate (CDC/OD/OADC} ------ (b)(6) Sent : Friday, January 31, 2020 6:34 PM ------~~ To: Brennan, Patrick (OS/ASPA} (b)(6) 1>; Bonds, Michelle E. (CDC/0D/OADC)(b)(6); Fine, Amanda "(:'~N:I-H::-/-O:~- D:}- :[:E:--] :--:=====...:....__, (ab~-~,<-6)>;C onrad, Patricia (NIH/N IAID) [E]=====:=;..--=- (b.),(.:=6, )>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1>; Lepore, Loretta (CDC/00/0CS} (b)(6)Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS),..:..!::====::::::_:_~(b)(6)>; Stecker, Judy (OS/10S} (b)(6); Murphy, Ryan (OS/ASPA}(b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B.(05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6)Subject: Re: Redfield/Fauc i nCoV op-edHi, Patrick -We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH commscan move thru with thei r editing/revisions.NIH-002110let me know if that sounds OK. We will likely not have a cleared version out of CDC until late Saturdayat the earliest.Take care,KateGet Out look for iOSFrom: Brennan, Patrick (OS/ASPA) (b)(6)Sent : Friday, January 31, 2020 5:31:46 PMTo: Bonds, Michelle E. (CDC/0D/OADC)_ ___ (~b)- (6=) >; Fine, Amanda (NIH/OD) [El(b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet, Courtney(NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)>Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS)(b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA)(b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B.":"::":--:-'.:-:-::--:-:-::=====::....-~~(OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate(CDC/OD/OADC) (b)( >Subject : Redfield/Fauci nCoV op-edCDC and NIH folks,Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding thereasons/thinking behind the policy announced today. I assume the right building blocks for it would bethe remarks they made today- which I believe you all should have the copy/notes for? I have theSecretary's, which we'll be sending around/post ing shortly and I'll make sure to re-up it here so you allhave it.It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!)Please let me know how I can help wi th t his.Best,PatrickPatrick BrennanDirector of SpeechwritingDepartmen t of Health and Hum an ServicesOffice: (b) (6) I Cell (b) (Predecisional/deliberative communicationNIH-002111From:Sent:Fauci, Anthony (NIH/NIAIO) [E)Thu, 6 Feb 2020 14:54:16 +0000To :(NIH/NIAID) [E]Cc:Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, HilaryConrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E]Subject: RE: ASF: rAzar/Pompeo op-edAtt achment s: 2 5 20 pompeo azar op-ed State - with Fauci tracked edits .. docxHere are my tr acke d ed its. Tha nks.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [El (b)(6)>Sent : Thursday, February 6, 2020 7:31 AM ------ == To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E]_______ Cb _>C6); Marston, Hilary (NIH/NIAID) [E] (b)(6)Cc: Conrad, Patricia (NIH/NIA ID) [E] CbH ; Routh, Jennifer (NIH/NIAID) [E](b)( >Subject: ASF: rAzar/Pompeo op-edSending to all of you simultaneously, in the interest of time. Our comments are due back at noon .From: "Brennan, Patrick (O5/ASPA)" (b)(6)>Date: Thursday, February 6, 2020 at 1:23:26 AMTo : "Routh, Jennifer (NIH/NIAID) [E]" ------- =(b.H...=,6)>, "Bonds, Michelle E. (CDC/OO/OADC)"(b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El" :::::======~~ (b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" --------- (b)(6)>, "Kane, EIieen (OS/ ASP R /OE A)" (b)(6J>, "Michael, Gretchen (O5/ASPR/OEA)",;___;__ _;____,:_::::==:::;(~b~~<6;-,)-,:,::B--:i:l:l:e---t:-,- -C-:o=urtney (NIH/NIA I D) [E]" (b)(6)> , "Le po re,Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)(6),"Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)"NIH-002112(b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:=(HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" ----------(b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" <ASPADeputies@hhs.gov>Subject : For review by noon Thurs: revised Azar/Pompeo op-edHi all,Attached is a largely new draft of the Azar/Pompeo op-ed tha t------------------------------- (b) (5) I've made a couple additions and edits to their new version , which I've tracked/flagged.NIAID, CDC, and OGC, please let me know if this looks OK by noon tomorrow . Thank you!Best,Pat rickNIH-002113From: Fauci, Anthony (NIH/NIAIO) [E)Sent: Thu, 6 Feb 2020 14:24:54 +0000To: Billet, Courtney (NIH/NIAID) [E]Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer(NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E]Subject: RE: ASF: for review, Azar coronavirus presser remarksAttachments: Secretary's remarks with minor Fauci edits.docxHere are my edits for Azar' s press commentsAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [E] (b)(6)Sent: Thursday, February 6, 2020 7-:2-9 -A-M- ---=-<~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El(b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>M1;a rston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)>Subject: ASF: for review , Azar coronavirus presser remarksPis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed.They also would like talking points from us, covering what you would say. These are really just aplaceholder. We could resubmit what we sent last time. Is there anything new you would anticipatesaying?From: "Brennan, Patrick (05/ASPA)" --------- Date: Wednesday, February 5, 2020 at 11:25 :33 PMTo: "Routh, Jennifer (NIH/NIAID) [El" (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)"(b)( >, "Galatas, Kate (CD"C.:'/.O":-::-D-::-/:-O::-A:-:D:-C::77)' ': -::==.,......(.b.)(.6.), "Fine, Amanda (NIH/OD) [E]" =====::::!.--=-=-~ -------- (b)(6)>, "Conrad, Patricia (NIH/NIAID) [El" (b)(6J>, "Kane, EIieenNIH-002116(OS/A SPR/OEA)" CbH6J>",M ichael, Gret chen (OS/ASPR/OEA)",;._..;___..;______;_::::==' (:b;);:(:6;=,)a>-",-,:,::B-"'i~.lle- t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele,Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" (b) (6)>,"Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)"(b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather(FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1,"McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)"CbH , "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)"----:~~====~(b:)_(6)_>,_ "K-e~ve.n.e;y,,· Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)>Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]"-------- (b)(6)>, "ASPA-Deputies" <ASPA-Deputies@hhs.gov > Subject : For review by 11 AM Thurs: Sec. Azar coronavirus presser remarksHi all,Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled pressconference on coronavirus- after which the plan is for Dr. Redfield and then Dr. Fauci, and thenwhoever from State and OHS (I think?) to speak.Can CDC, NIAID, OGC, FDA, and ASPR let me know if this looks OK by 11 AM tomorrow?And once CDC and NIAID have their draft TPs, it would be great to see those as well.Thank you!- PatrickNIH-002117From: Fauci, Anthony (NIH/NIAID) [ElSent : Thu, 6 Feb 2020 03:59:18 +0000To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [ElCc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence(HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda,Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA)Subject: RE: Coronavirus collaborating centerYes. Thanks you.-----Original Message----From:Grigsby , Garrett (HHS/OS/OGA) --------- (b) (6)>Sent: Wednesday , February 5, 2020 8:-42- A-t'-vl- -, ,,.,..,-= To: Fauci, Anthony (NIH/NIAJD) [E] (b)( >; Lane, Cliff (NTH/NJACD) [E]------(b)-(6) - ------- Cc: Marston , Hilary (NTH/NTATD[)E ] (b)(6) ; Zebley, Kyle (HHS/OS/OGA)....................... ----, (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara(HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff, Colin(HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ;Alexander, Thomas (OS/OGA) ---,---------(b) (6)> Subject: FW: Coronavirus collaborat ing centerlmportance: HighDrsF & L,Confinning that you want me to reply in the affirmative asap ... ?-----Original Message----from: Lamourelle , Gabrielle (HHS/OS/OGA) __________ (b)(6_), >Sent: Wednesday , Febrnary 5, 2020 6:5-0- A-M-- -~ ~= To: Grigsby , Garrett (HHS/OS/OGA) -------(b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA) (b) ( >; Burr, Mara(HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) (Cc: Tracy Carson (b)( ; Smith, Steven T (Geneva) (b) ( art, Jessica L.(HHS/OS/OGA) Cb) C ; Levine, Maya (OS/OGA) (b ood, Rachel(HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) --------- Subject: FW: Coronavirus collaborat ing centerlmportance: HighDear Garrett and all,I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with therequest that we review and provide a reply as quickly as possible. The letter, as usual form, says they will goforward in 8 weeks if they hear no objection from us.Thank you,Gabrielle-----Original Message--------- --,;-;= From: TULER, Matias Cb()6 )Sent: Wednesday , February 5, 2020 9:35 AM(b) (5)If you have any questions, let me know.NIH-002145To: Lamourelle, Gabrielle (HHS/0S /OGA)Cc: OGA Multilateral <OGAmu ltilateral@hhs.gov >Subject: RE: Coronavirus collaborating centerDear Gabrielle ,Many thanks for the email.(b)(1 sent you an email with the letter just after we talked. 1 do not know if you received it. ram attaching the letter tothis email again, just in case.Thank you very much in advance.Best regards ,MatiasMatia s TulerProgramme ManagerWHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health OrganizationGeneva , SwitzerlandOffice: (b) (6)Web: http://www .who.int/collabora tingcentre s/infonnat ion/en/http://www .who.i nt/about/collabo rations/expert panels/en/Follow WHO on Facebook, Twitter, YouTube, Instagram-----Original Message- ----From: Lamourelle , Gabrielle (HHS/0S /OGA) -----------(b-)(6) > Sent: Wednesday , February 5, 2020 9: 17To: TULER, Matias (b)(6)Cc: OGA Multilateral <OGArnu ltilateral @hhs.gov>Subje ct: Coronaviru s collaborating centerDear Matias,Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electroniccopy as well and J will send back immediately to our office for a rapid reply.With best wishes,Gabrielle LamourelleDeputy Director, Multilateral RelationsHHS Office of Global AffairsSent from my iPhoneNIH-002146From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAID) [E)Thu, 6 Feb 2020 02:55:19 +0000Kerr, Lawrence (HHS/0S/OGA)Grigsby, Garrett (HHS/0S/OGA)RE: Spoke with Soumya re: evolut ionary origin of nCoVI do not see any prob lem with your doing this. Go for it.Best,TonyFrom: Kerr, Lawrence (HHS/0S/OGA) ---------- Sent : Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( >Cc: Grigsby, Garrett (HHS/OS/OGA'")=======~ ("b")'~(6)>Subject: Spoke with Soumya re: evolut ionary origin of nCoVDr. Fauci,I welcome you r advice please . Much thanks,LarryNIH-002149(b) (5)From:Sent :To:(b)(6)Wed, 11 Mar 2020 19:30 :25 -0400John M JessupSubject: Re: You are great - a thoughtKim:Thanks for the note. That is exactly what the cdc is sta1i ing to do.Best,TonyOn Mar 11, 2020, at 7:22 PM, John M Jessup --------- (b)(6) wrote:Tony,We have seen each othe r over the decades. I am the (b)(6) from NCIwho decreid the lack of info rmation about Eboal since it was limited to fruit bats as areservoir.An idea about testing . Maryland sti ll has testing limited to subjects withsymptoms who have contact with people from affec ted areas or who real ly ill with arespiratory infectionWhy not forget the contacts and test those with flu-like symptoms without theneed for contacts but instead test for flu and if that is negative move on to covid -19.That would still be a tr emendous demand so ... go to a formal two -ti er t est wh erePCR is done with approved PCR primers and if that is positive then the confirmation is witha FDA test for covid -19.There are a lot of manufacturers of PCR primers, most clinical labs have PCRmachines so that screening tests ought to be supported wit hout a lengthy FDA clearance ifit w innows the number of patients who need a formal test.You are terrific . Keep it up with common sense as opposed to whatever the top ofthe administration suggests. I bet that the primer manufacturers would be supportive .KimJ. Milburn Jessup, MD, FACSResearch ScientistDivision of ResearchWashington DCVAMC50 Irving Street NWWashington, DC 20422(b)(6) or_ ______ (°b" )'""(=6' )Affil iate Professor - Systems BiologyNIH-000677College of ScienceGeorge Mason University(b)(6)----(b)(-6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIHNIH-000678From: (b)(6)Sent : Wed, 5 Feb 2020 08:56:13 -0500To: Baden, Lindsey, M.D .Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea(NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E]Subject: Re: favor(b) (6). (b) (4)On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M.D. <lbaden@nejm.org>wrote:Ton'l,'------------------------- (,.b.)".(,"6 )..(b." )' .~.,.l. ,LindseyFrom : "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6)Date: Tuesday, February 4, 2020 at 7:06 PMTo: "Baden, Lindsey, M .D." <lbaden@ne j m.org>--------~= Cc: "Marston, Hilary (NIH/NIAID) [E]" CbH6")C onrad, Patricia(NIH/ NIAID) [E]" Cb)( , "Lerner, Andrea (NIH/ NIAID) [E]",;.__:_ _ __;_...:......:...(~.b:):~:C=;;6-,-)-,:,: -L:-a- n-e-, -c=:l:if-:f:: --(: N--::1--:H:---/:N-'. IAID) [El" (b)(6)> ,"Mo rens, David (NIH/N IAID) [El" CbH6)>Subject : RE: favorLindse :Best regards,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-03NIH-002173(b) (6). (b) (4)31 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: Cb()6 )FAX: (301) 496-4409E-mail: (b) (6)The information in this e-mail and any of its attachments is confidential and maycontain sensit ive information . It should not be used by anyone who is not the originalintended recipient. If you have received this e-mail in error please inform the senderand delete it from your mailbox or any other storage devices. The National Institute ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender 's own and not express ly made on behalf of the NIAID byone of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm.org>Sent: Tuesday, February 4, 2020 3:3-5- P-M- -----=-c-c= To: Fauci, Anthony (NIH/NIAID) [E)" ======= (b=)( :6:-)!~Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6); Conrad, Patricia(NIH/NIAID) [E] (b)(6)Subject: Re: favorTony (and Hilary),Much appreciated. ------- (b) (6), (b) (4) .Thank you,LindseyFrom : "Fauci, Anthony (NIH/NIAID) [E]" --------- (b)(6)Date: Tuesday, February 4, 2020 at 2:16 PMTo : "Baden, Lindsey, M.D." <lbaden@nejm.org >Cc: "Marston, Hilary (NIH/NIAID) [E]" J CbC)6 J, "Conrad, Patricia(NIH/N IAID) [E]" (b)(6)Subject: RE: favorLindsa :TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthNIH-002174(b) (6), (b) (4)Bethesda , MD 20892-2520Phone: Cb) (6)FAX: (301) 496-4409E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confidential and maycontain sensitive information . It should not be used by anyone who is not the originalintended recipient. If you have received this e-mail in error please inform the senderand delete it from your mailbox or any other storage devices . The National Institute ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender's own and not expressly made on behalf of the NIAID byone of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm.org >Sent: Tuesday, February 4, 2020 12-:3-1- P-M- ---::-:-c-= To: Fauci, Anthony (NIH/NIAID) [E)- ------- (b)(6) Subje ct: favorTonv.Thank you for considering,Lindsey(b) (6). (b) (4)This email message is a private communication. The information transmitted, includingattachments, is intended only for the person or entity to which it is addressed and maycontain confidential, privileged, and/or proprietary mater ial. Any review, duplication,retransm ission, distribution, or other use of, or ta king of any action in reliance upon, thisinformation by persons or entities other than the intended recipient is unauthorized by thesender and is prohibited . If you have received this message in error, please contact thesender immed iately by return email and delete the original message from all computersystems. Thank you.This email message is a private communication . The information transmitted, includingattachments, is intended only for the person or entity to which it is addressed and maycontain confidential , privileged, and/or proprietary mater ial. Any review, duplication,retransm ission, distribution, or other use of, or taking of any action in reliance upon, thisinformation by persons or entities other than the intended recipient is unauthorized by thesender and is prohibited. If you have received this message in error, please contact thesender immed iately by return email and delete the original message from all computersystems. Thank you.This email message is a private communication. The infonnation transmitted ,including attachments, is intended only for the person or entity to which it isaddressed and may contain confidential, privileged , and/or proprietary materia l. Anyreview, duplication , retransmis sion, distr ibution , or other use of, or taking of anyaction in reliance upon, this information by person s or entities other than theintended recipient is unauthorized by the sender and is prohibited. If you haveNIH-002175NIH-002176received this message in error, please contact the sender immediately by returnemail and delete the original message from all computer systems. Thank you.From:Sent :To:(b)(6)Wed, 5 Feb 2020 08:41:40 -0500Baden, Lindsey, M.D .Subject: Re: favorThanks , Lindsey. I am always happy to help in any way I canOn Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M.D. <lbaden@nejm.org>wrote:Tony,On a different note, as the spread of the nCoV-2019 virus is so complex and fast moving,any advice on how we at the Journal can help in the response would be great.Your advice is always appreciated as we all try to get it right and be responsive.LindseyFrom: "Fauci, Anthony (NIH/N IAID) [E]" ---------- (b)(6)Date: Tuesday, February 4, 2020 at 7:06 PMTo: "Baden, Lindsey, M .D." <lbaden@nejm.org> -------- == Cc: "Marston, Hilary (NIH/ NIAID) [E]" (b)(6), "Conrad, Patricia(NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]"~___;_ _ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- .--------- CbH >, "Lane, Cliff (NIH/ NIAID) [El" CbH6) "Mo rens, David (NIH/N IAID) [EJ' (b)(6)Subject : RE: favorLindsey:Best regar ds,TonyAnthony S. Fauci, MDDirectorNat ional Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520Nat ional Institutes of HealthBethesda , MD 20892-2520NIH-002177(b) (6). (b) (4)Phone: Cb) (FAX: (301) 496-4409E-mail: (b)(6) --------- The information in this e-mail and any of its attachments is confidential and maycontain sensitive information . It should not be used by anyone who is not the originalintended recipient. If you have received this e-mail in error please inform the senderand delete it from your mailbox or any other storage devices . The National Institute ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender's own and not expressly made on behalf of the NIAID byone of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm.org>Sent: Tuesday, February 4, 2020 3:35 PMTo: Fauci, Anthony (NIH/NIAID) [E) -------=- (b')"("='6)Cc: Marston, Hila ry (NIH/NIAID) [E) CbH ; Conrad, Patricia(NIH/NIAID) [E] (b)(6)>Subject: Re: favorTony (and Hilary), ---- ~=--c~= Much appreciated -------(b)-(6) . (b)(4). Thank you,LindseyFrom: "Fauci, Anthony (NIH/ NIAID) [E]" ---------- (b)(6)Date: Tuesday, February 4, 2020 at 2:16 PMTo: "Baden, Lindsey, M.D." <lbaden@nejm .org>Cc: "Marston, Hilary (NIH/NIAID) [E]" (b)(6), "Conrad, Patricia(NIH/NIAID) [E]" CbH6)Subject: RE: favorLindsay:TonyAnt hony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31 , Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone : Cb()6 )NIH-002178(b) (6). (b) (4)FAX: (301) 496-4409E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confidential and maycontain sensitive information . It should not be used by anyone who is not the originalintended recipient. If you have received this e-mail in error please inform the senderand delete it from your mailbox or any other storage devices. The National Institute ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender's own and not expressly made on behalf of the NIAID byone of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm.o rg>Sent: Tuesday, February 4, 2020 12:31 PM ------~~ To : Fauci, Anthony (NIH/NIAID) [E) (b)(6)>Subject: favorTon ~-------------------------- ~(b~~=(6)~. ~(b) ~(=~Thank you for considering,LindseyThis email message is a private communication . The information transmitted, includingattachments, is intended only for the person or entity to which it is addressed and maycontain confidential, privileged, and/or proprietary mate rial. Any review, duplication,retransm ission, distribution, or other use of, or taking of any action in reliance upon, thisinformation by persons or ent ities other than the intended recipient is unauthorized by thesender and is prohibited . If you have received this message in error, please contact thesender immed iately by return email and delete the original message from all computersystems. Thank you.This email message is a private communication . The information transmitted, includingattachments, is intended only for the person or entity to which it is addressed and maycontain confidential, privileged, and/or proprietary material. Any review, duplication,retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, thisinformation by persons or entities other than the intended recipient is unauthorized by thesender and is prohibited. If you have received this message in error, please contact thesender immed iately by return email and delete the original message from all computersystems. Thank you.This email message is a private communication. The infomrntion transmitted,including attachments, is intended only for the person or entity to which it isaddressed and may contain confidential, privileg ed, and/or propri etary material. Anyreview, duplication , retransmis sion, dis tribution, or other use of, or taking of anyaction in reliance upon, this information by persons or entities other than theintended recipient is unauthorized by the sender and is prohibited. If you havereceived this message in error, please contact the sender immediately by returnemail and delete the origi nal mes sage from all compute r systems . Thank you.NIH-002179From:Sent :To:Subje ct:For discussion.Fauci, Anthony {NIH/NIAID) [ElWed, 5 Feb 2020 11:52:41 +0000Conrad, Patricia {NIH/NIAID) [ElFW: INTERVIEW-A HABER/ A NEWSFrom: GULSEN EDA ULUSOY <EDA.ULUSOY@ahaber .com .tr>Sent: Wednesday, February 5, 2020 3:23 AM --------=-:-= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) _______ _,Subject : INTERVIEW-A HABER/ A NEWSDear Mr. Fauci,This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News.We wou ld like to take few minutes of your time and kindly ask if we could possibly have theopportunity to make a Skype interview with you about China coronavirus outbreak.We can have the interview this week or next week. I can arrange it according to yourprogramme.It will on ly take 15 minutes of your time.We would really apprecia te if we can make this interview.Thank you for your kind consideration.I'm look ing forward to your reply.Sincerely,Eda UlusoyCorrespondentNIH-002180From:Sent :To:Subject ::et us discuss.Fauci, Anthony (NIH/NIAID) [E)Wed, 5 Feb 2020 11:52:11 +0000Conrad, Patricia (NIH/NIAID) [E)FW: Interview invitation from Dialogue CGTNFrom: Bai Jacinta (b)(6)Sent: Wednesday, February 5, 2020 2:58 AM To: Fauci, Anthony (NIH/NIAID) [E] -------------- -(-b)=( =>;, F auci, Anthony {NIH/N IAID) [E] (b )( 6) >Subj ec t : Interview invitation from Dialogue CGTNDear Mr. Fauci,This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well.I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time.I read the interview to you on New York Times and sincerely wish that you could share more with ourglobal audience. It would be our honor to have you on.Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling theoutbreak, cooperat ion in international communities, prevention measures and so on.Please kindly let me know if you are available for the show . I'll send the proposed questions beforehandand book the closest studio for you.Appreciate it!Best,Jacinta BaiDialogue, CGTNNIH-002181From:Sent :To:Cc:Subje ct:David:Fauci, Anthony (NIH/NIAID) [E)Wed, 5 Feb 2020 11:34:46 +0000Ho, David D.Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [ClRE: 2019-nCo\/Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad(copied here) to set up a call. I down at the Congress and White House most of the day, but wecan probably squeeze a call in between meetings .Best,TonyFrom: Ho, David D (b)(6)>Sent: Tuesday, February 4, 2020 12:48 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>Subject: 2019-nCoVTony,Greet ings. As you can see below, our institute has moved. We are now part of Columbia.Do you have a brief moment to chat about the new coronavirus?Best,DavidDavid D. Ho, M.D.Director, Aaron Diamond AIDS Research CenterClyde and Helen Wu Professor of MedicineDirector, Wu Family China CenterColumbia University Vagelos College of Physicians and Surgeons701 W. 168th Street, HHSC 1102New York , NY 10032NIH-002182From: Fauci, Anthony (NIH/NIAIO) [ElSent : Wed, 5 Feb 2020 11:17:05 +0000To: Collins, Francis (NIH/OD) [ElCc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia(NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID)(b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) --------- Subject: RE: CoronavirusFrancis:(b)(5)-------------- (b)(5) Happy to discuss further. Thanks,TonyFrom: Coll ins, Francis (NIH/OD) [ElSent : Wednesday, February 5, 2020 5:58 AM(b)(6)------~~ To: Fauci, Anthony (NIH/NIAID) [E;] !====== (b=)-(;~6)~Cc: Tabak, Lawrence (NIH/OD) [El CbH6)>; Shapiro, Neil {NIH/OD) [El(b)(6)Subject: FW: CoronavirusImport ance: HighHey there Tony,Thanks, FrancisFrom: Shapiro, Neil (NIH/OD) [El -------- (b)(6)> Sent: Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins, Francis (NIH/OD) [El CbH6)>; Tabak, Lawrence (NIH/OD) [El(b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6)Schwetz, Ta r,a_ -(: N--::l--H::-7/:0:-:D:-:)-:[-=E:l:.:====---...,_ (b,.). _=(.6.)>NIH-002183(b) (5)Cc: Shaya, Cecile {NIH/OD) [El (b)(6) ______._...Subject: RE: CoronavirusImport ance: HighFrom: Shapiro, Neil {NIH/OD) [ElSent: Tuesday, February 4, 2020 4:46 PMTo: Collins, Francis {NIH/OD) [E]----- -(-b=")'(-"="6J>; Tabak, Lawrence (NIH/OD) [El(b) (5)--~~~~====!(b:),( _; _Jo-hn~so~n, Alfred (NIH/OD) [El (b)(6)>; Wolinetz, Carrie {NIH/OD) [El CbH6; JHallett , Adrienne (NIH/OD) [El (b)(6)Schwetz, Tar .a. .- (: N--::1--H::-7/:0:-D::-):-::[-:E:-l::--====::.;__--,;,- (b"HS=6"')"Cc: Shaya, Cecile {NIH/OD) [El ______(b)(._6.). .Subject: RE: CoronavirusFrancis,(b) (5)NeilNIH-002184From: Shapiro, Neil (NIH/OD) [E]Sent: Wed nesday, January 29, 2020 2:34 PMTo: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [ElCbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie":""."'."".""."-:-:-:-:-:-:::-====~~-~.;.,(NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)>Subject: RE: CoronavirusI'm sending them the first part, thanks .From: Collins, Francis (NIH/OD) [E] (b)(6)Sent: Wed nesday, January 29, 2020 5:23 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E) (b)(6) Shapiro, Neil (NIH/OD) [E)(b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie-~---~==:=:!.. __ __:_~=(NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6)Subject : RE: Coronavirus(b) (4)FCFrom: Tabak, Lawrence (NIH/OD) [El (b)(6)Sent: Tuesday, January 28, 2020 6:25 PM ------~= To: Shapiro, Neil (NIH/OD) [E] (b)(6) Collins, Francis (NIH/OD) [E](b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie(NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6)Subject : Re: Coronavirus(b)(5LarryFrom: "Shapiro, Neil (NIH/OD) [E]" --------- (b)(6)>Date : Tuesday, Jan uary 28, 2020 at 5:31 PMTo: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]"--------- CbH >, "Johnson, Alfred (NIH/OD) [E]" (b)(6) 11 W o Ii net z, Carrie (N IH/OD) [E]" CbH >, "Hallett, Adrienne (NIH /OD) [E]"(b)(Subject: Coronavirus(b)(5)NIH-002185(b) (5)NeilNIH-002186From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Wed, 5 Feb 2020 04:18:25 +0000To: Conrad, Patricia (NIH/NIAID) [ElSubject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meetingat the Ritz Carlton (22nd and M St. NW), Washington, D.C.No dinner.From: Conrad, Patricia (NIH/NIAID) [E] ---------(-b)(6)> Se nt: Tuesday, February 4, 2020 11:21 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6)Cc: Barasch, Kimberly (NIH/NIAID) ~[c::.========-- (cbc')"-("=6)Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the RitzCarlton (22nd and M St. NW), Washington, D.C.See highlight - will you and ---C-b><· a tt end the dinner. Pis advise.Patricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Infectious DiseasesThe National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301 -496 -4409 faxDisclai mer:The informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information . It should not be usedby anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not acceptliability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives .From: Marlene Colucci <mcolucci@businesscouncil.com>Se nt: Friday, January 31, 2020 2:00 PMTo: Fauci, Anthony (NIH/NIAID) [E)-------= (b-)c(c-6-)=Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein<David.Rubenstein@carlyle.com>; MaryPat Decker <marypat.decker@carly le.com>Subject : Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton(22nd and M St. NW), Washington, D.C.Dear Dr. Fauci,NIH-002191On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of TheCarlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in ourmeet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade."{See form al invitat ion attached as well as list of CEO members).We would like for you to part icipate in a 50 minute fireside chat wi th David Rubenstein {and possibly Dr.Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade.We want to give our CEOs insights into what the next 10 years will bring in terms of detection, diagnosisand t reatment of diseases. All conversations are strictly off the record and closed press. We will coverall lodging and t ransportat ion.As you know, The Business Council is comprised of the chief executive officers of the largest globalcorporations, representing all segments of the economy . We expect at least 150 CEO members, spousesand speakers to be in attendance.As a participant you and your spouse are also invited to join us for our special reception, dinner andspeaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunityfor you to meet our CEO members and spouses, speakers and othe r special guests in an informalatmosphere.If you are interested and available, please let me know. We can also set up a very brief call with you todiscuss any additiona l details and answer any questions you may have. We look forward to hearingfrom you and wou ld be honored to have you participate with us again.Warmest regards,MarleneMarlene ColucciEXECUTIVEDIRECTOR'I B1USINESS~ COL \JClLT: 202-298-7650C Cb()6 )F: 202-785-0296NIH-002192From: Fauci, Anthony (NIH/NIAIO) [E)Wed, 5 Feb 2020 04:17:19 +0000Routh, Jennifer (NIH/NIAID) [E]Billet, Courtney (NIH/NIAID) [E]Sent:To:Cc:Subject: FW: Comment on story about how confident people feel about the ir govt'sresponse to a health epidemicPlease try to draft a response for me. Thanks .From: Rajeshni Naidu-Ghelani <Rajeshni.Naidu-Ghelani@ipsos.com>Sent: Tuesday, February 4, 2020 12:23 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------ (.b.-),-..(.,6=)Subject: Comment on story about how confident people feel about their govt's response to a healthepidemicHi Dr. Fauci,I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to howpeople responded to a recent global lpsos poll about the threat of a major health epidemic in theircountry in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 19-11/ a-more-dangerous-world -fear-2019.pdfI was hoping to get your comments on this, considering your expertise in infectious disease control.Below are some questions. If you could respond via email, that would be great as I am on a tightdeadline to get this story up. If it's easier to give you a call, I can do that as well. Please let me knowwhat works best. The story will be published on lpsos.com, on social media and our various countrywebsites. Thank you and I look forward to your response.1. In our survey of more than 18,500 people in 28 countries done in late last summer, more thanhalf (51%) of people said there was threat of a major health epidemic in their country in the next12 months with people in emerging markets at the top of the list. Are you surprised by thisresult? It's among the highest reading for this question since the Ebola outbreak in 2014 whenthe percentage climbed to 59%.2. The U.S. is the only developed country in the top 10 list where most people think a major healthepidemic will occur. Why do you think this is?3. A follow up question to the previous one is how confident people are that their governmentcould protect them or respond effectively if such an outbreak was to occur. Over half globallysaid they were confident in their gov't's response. Do you think people have a lot of trust inthose in power to do the right thing in times of an outbreak?4. Seven of the top 10 countries where people had the most confidence in govts are in thedeveloped world . How important are developed healthcare systems when it comes to outbreakslike the coronavirus?5. Likewise, many countries at the bottom of this list are emerging markets. What can govts inthese countries do to ease peoples' fears on how they are or will handle an outbreak like thecoronavirus?NIH-0021936. How difficult is it for governments and health officials to prevent the spreading of a virus likethis before it becomes a pandemic? What measures can be taken?Please free to add any add itional information that you thin k may be relevant . I hope to hear from yousoon.Regards,RajeshniRajeshni Naidu-Ghelani I Data JournalistPublic Affairs160 Bloor Street East, Suite 300M4W 189 Toronto - CanadaPhone: +1416 572 5143Mobile: ,.._ __ ...>;;<~rajesbni .naidu-ghelani@ipsos.comwww.ipsos.comCtt,\NQE THE OAt.'!1GAMECHANGERS IINIH-002194From: Fauci, Anthony (NIH/NIAID) [E)Sent : Wed, 5 Feb 2020 04:12:18 +0000To: Routh, Jennifer (NIH/NIAID) [E]Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia(NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E]Subject : RE: for review: responses for Elemental news site (not urgent)I made some modifications. You can send it. Thanks.From: Routh, Jennifer (NIH/NIAID) [E) (b)( >Sent: Tuesday, February 4, 2020 4:11 PMTo: Fauci, Anthony (NIH/NIAID) [E]_ _____ ('"b'~..-(.6=) >Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E](b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg(NIH/NIAID) [E) (b)(6)Subject : for review: responses for Elemental news site (not urgent)Dr. Fauci -This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellnessnews site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have draftedproposed responses for you in red below . Please let me know if you have edits. I will send responsesback to the reporter attributed to you.Thanks,JenFrom: Rob Britt (b) (6)Sent: Sunday, February 2, 2020 5:1-0 -P-M- -- ---..-,~ To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)(6J> Subject: Coronavirus - reporter's questionsHi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual andlevel-headed, and I have seen your comments on NPR Friday and in the NY Times over theweekend , so I hope you could comment very briefly for our story:-- What's your expectation for whether this will become a pandemic?The novel coronavirus outbreak will likely become a pandemic. We know the virus is verytransmissible. The infection continues to accelerate and there is efficient transmission inchina. If sustained transm ission also occurs in other countries throughout the world, theoutbreak would fulfill the definitive of a pandemic-- Pandemic does not necessarily equate to a terrible situation, compared to, say bad fluseasons. What 's your expectation on the potential severity of this coronavirus?It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remainslow, if it is easily t ransmissible, the global impact can be significant .-- And your suggestion to people in the U.S. who might be very concerned?NIH-002195We are treating t he emergence of a novel coronavirus as a very serious public healththreat. However, the risk to the general Amer ican publ ic remains low at this time . Weunderstand that people may be wor ried . We ask that people not let fear or panic guidethe ir actions .Thanks for any help you can provide.Cheers,RobRobert Roy BrittTop Writer on Medium in Science & Health.Contributor to OneZero (science) & Elementa l (health).Former editor-in-chief of Live Science and Space.com.(b)(6)(b)(6)NIH-002196From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Wed, 5 Feb 2020 04:06:33 +0000Cassetti, Cristina (NIH/NIAID) [E]Subject: FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr.Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concernsPlease handle.-----Original Message-----From: Jon M (b) (61Sent: Tuesday, February 4, 2020 4:55 -PM- ------, a-s-r,= To: Fauci, Anthony (NTH/NlAID) [E] (b) ~Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo Clinic)regar ding Chinese 15 minute Coronavirus test and other concernsFrom: Jon M (b) (6}To: ocpostoffice@niaid .nih.govSubject: Atten tion Meylin - Forward of my email lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci(NlAID/NII-1}Date: Feb 4, 2020 I :45 PMHello Meylin,Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of hisassistant, Joseph Roberts, to Dr. Fauci.Jon MarkowitzFrom : Jon M (b) (61To: (b)(6)Subject: JOE -We spoke on phone today ... Please forward my email with reference links to Dr. Gregory PolandDate: Feb 4, 2020 12:57 PMHello Joseph Roberts (Mayo Clinic),We spoke on phone today ...Please forward my email with reference links to Dr. Gregory Poland Thank you, Jon MarkowitzFeb 4 , 2020Dear Dr. Gregory PolandI saw your appearance Feb 3 on a CNBC news program:https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4'We're basically at a pandemic now' : Mayo Clinic physician on corooavirusFyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 yearsold and live in Los Angeles.A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there wereefforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical theNIH-002197NIH-002198White House arrange for the new Chinese test to be available in the US everywhere immediately.This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY.At this point, the NTH, CDC and White House shou ld have already obtained the Chinese 15 minute test for the virusand implement at all US medical centers and airports receiving travele rs from the infectious regions.Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know theyare infectious, whether returning from infection zones or are infected by others already here, I am hoping you andother infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all otheragencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country byair and sea with the Chinese 15 minute test as well as pull out all the stops to develop an even quicker test that'sportable.As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks fromincreasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on theprecipice of an unstopable runaway epidemic.What is also desperately needed from the federal government are frank and honest recommendations regarding whatis necessary to prevent becoming infected such as:surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipesalong with specific protocols on how not to bring the vims particles back to ones car, borne and possessions.It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators beramped up to huge scale. Without adequate numbers of these, exam gloves and eye protection this country will notbe capable of containing this epidemic .Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce.Thank you very much for your attention to this issue.Jon MarkowitzLos AngelesReferences:https://www .rt.com/news /4 79705-china-develop-coronav irus-rap id-test/China develop s rapid Coronavirus test that works in under 15 MINUTES3 I Jan, 2020 I 0:48Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus inunder fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction.Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institutefor Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to theXinhua news agency.The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rateof 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further.The first batch of kits has reportedly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan ,in Hubei province.https://www.youtube.com/watch?v=Wg33oZd0- R4'We're basically at a pandemic now': Mayo Clinic physician on coronavirus114,173 viewsNIH-002199•Feb 3, 2020CNBC Televisionhttps://www.youtube.com/watch?v=VdUi kwuw7T11 confinned US coronavirus cases, experts warn of pandemic I ABC News157,773 views•Feb 3, 2020ABC Newshttps://www.youtube.com/wa tch?v=8Hjy3UfaTScCoronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate129,190 views•Feb 3, 2020MedCramhttps://www .youtube.com/watc h?v=GpbUoLvpdCoCoronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA329,919 views•Feb 2, 2020MedCramhttps://www.youtube.com/user/MEDCRAMv ideos/videosMedCram youtube channel[Dr. Roger Seheult - https://W'.vw.medcram .com/]https://www.youtube.com/watch?v=z05Z rMfKUDcCoronavirns , Contag ion and Complications228,007 views•Feb 2, 2020Dr. John Campbellhttps: //www.youtube.com/watch?v=u7D3AoNdp84Wuhan virus compared to MERS and SARS45,569 views•Feb 3, 2020Dr. John Campbellhttps://www.yo utube.com/user/Campbellteaching/videosDr. John Campbell youtube channe lhttps://www.youtu be.com/wa tch?v= zczkLZN 194Mayor de Blasio Holds Media Availability334 viewsFeb l , 2020NYC Mayor's Officehttps://,vww.youtube.com/wa tch?v=oMl-9Kvoj7OCoronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing]121,648 views•Streamed live on Jan 3 l, 2020QuickTake by BloombergFrom:Sent :To:Subject :Attachment s:Please handle.Fauci, Anthony (NIH/NIAID) [ElWed, 5 Feb 2020 04:03:41 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: coronavirusWuhan Coronavirus Vaccine.docxFrom: John Howard _________ C_>b<_·>Se nt: Tuesday, February 4, 2020 6:05 PMTo: Fauci, Anthony (NIH/NIAID) [E]_ _____ ..(,b,")("="6)Subject: coronavirusDear Dr, Fauchi,I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we mayhelp in this effort. (b)(4Thanks for your attention regarding this matter.Sincerely,John Howard, PhDPresident ABI(b)(6)NIH-002200,___ (,.b..)", ("4)"From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Wed, 5 Feb 2020 03:49:07 +0000Fleisher, Thomas (NIH/CC/OLM) [V)RE: QuestionNo problem.From:F leisher, Thomas (NIH/CC/OLM) (V) ------- (b) (6) > Sent: Tuesday, February 4, 2020 9:37 PMTo: Fauci, Anthony (NIH/NIAID) [E] -------=- CcHb-=- >Subject: Re: QuestionTony,Would you be willing to have your statement "we are in the middle of influenza season ... " included inthe Academy 's on line Practice Matters email Thursday going out to all members (attri buted to you)along with a link to the CDC webs ite devoted to Coronavirus?Thanks,TomFrom: "Fauci, Anthony (NIH/NIAID) (E)" (b)( >Date: Tuesday, February 4, 2020 at 3:14:47 PMTo: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- ~=Cc: "Conrad, Patricia (NIH/NIAID) [E]" --------- Subject: RE: QuestionTom:Right now nothing specific to communicate except that we are still in the middleof an influenza season and the things that we do to prevent spread of flu (i.e.hand washing, social distancing from crowds) are the same things that we woulddo if we have transmissions of nCoV here .Best,TonyAnthony s. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520Nation al Institutes of HealthBethesda , MD 20892-2520Phon e: (b)(6)FAX : (301) 496-4409E-mail : -------- (b)(6)NIH-002201The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Fleisher, Thomas (NIH/CC/DLM) [V] --------- (b) (6)>Sent: Tuesday, February 4, 2020 1:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E]- ------- CbH6J> Subject : QuestionTony,I was asked if th ere is any message th at the A&I community should receive in regards to the curr entCoronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medicalboards are releasing updates and recommendat ions but the question posed to me was is there anythingAAAAI should communicate to our membe rs? Thank you for considering this question.Regards,TomNIH-002202From:Sent:To:Subject:Sylvia:Fauci, Anthony (NIH/NIAIO) [ElWed, 5 Feb 2020 03:48:11 +0000Sylvia BurwellRE: A couple of quick quest ions.Masks are really for infected people to prevent them from spreading infection to people whoare not inf ected rather than protecting uninfected people from acquiring infection. The typ icalmask you buy in the drug store is not really effective in keeping out virus, which is small enoughto pass through the material. It might, however, provide some slight benefit in keep out grossdroplets if someone coughs or sneezes on you. I do not recommend that you wear a mask,particu larly since you are going to a vey low risk location. Your inst incts are correct, money isbest spent on medical countermeasures such as diagnostics and vaccines.Safe travels.Best regard s,TonyFrom: Sylvia Burwell (b)(6)>Sent : Tuesday, February 4, 2020 10:24 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6)Subject : A couple of quick questions .Begin forwarded message:From: Sylvia Burwell (b)(6)Date: February 4, 2020 at 9:35:03 PM ESTTo: Sylvia Burwell (b)(6)Subject: Fwd: Advice re a donationEXTERNAL EMAIL: Use caution with links and attachments.Begin forwarded message:From: Sylvia Burwell ----------- (b)(6)Date: February 4, 2020 at 9:33:47 PM ESTTo: Tony Fauci (b)(6)>Subject: Fwd: Advice re a donationNIH-002203TonyTwo quick questions1. I am travel ing to (b)(6) Folks aresuggesting I take a mask for the airport. Is this something I should do.2. Please see below. Do the Chinese have needs for support right now?Would money be better spent on diagnostics or vaccine work?Thanks!SylviaBegin forwarded message:From: Richard Falkenrath ---------- (b)(6) Date: February 4, 2020 at 5:27:32 PM ESTTo: (b)(6) Sylvia Mathews Burwell(b)(6)Subject: Advice re a donationHi SylviaI hope this find you well.Quick question, a little bit from left field, but drawing on yourexperience at Gates and HHS. Ray Dalio and Bridgewater areinterested in making a very sizable donation to help China dealwith the global public health challenge arising from the newcoronavirus. Any suggestions of where we should look todonate the funds?Thanks so much. ----------- (b) (6) looking forward to seeing you again soon.Richard(b)(6)NIH-002204From:Sent:To:Fauci, Anthony (NIH/NIAID) [E)Wed, 5 Feb 2020 00:42:06 +0000Conrad, Patricia (NIH/NIAID) [E)Subject : FW: Interview wi th Voice of AmericaLet us discuss.Anthony S. Fauci, MDDirectorNational Institu te of Allergy and Infectious DiseasesBuilding 31, Room 7 A-0331 Center Driv e, MSC 2520National Institu tes of HealthBethe sda , MD 20892-2520Phone: (b) (6)FAX: (301) 496-4409E-mail: (b)(6)The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. Itshould not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITorplease inform the sender and delete it from your mailbox or any other storage devices. The National Institute ofAllergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's ownand not expressly made on behalf of the NlAID by one of its representatives.-----Original Message-----From : Rattaphol Onsanit <ronsanit @voanews.com >Sent: Tuesday, February 4, 2020 2:42 P-M-- ---~~ To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) >Subject: Interview with Voice of AmericaDear Dr. Fauci,l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony yearsago.l'm now working on a news story about how developing countries equip themselves with medical readiness andpolicy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked atGlobal Health Sec11rity Index, Thailand was ranked the highest in its ability to tack le epidemics ahead of Japan ,Korea and Singapore. It's also by far the highest among developing countries.I'm curious to find out about contributing factors for developing countries' readiness to effectively handle anoutbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during thisoutbreak and T hope that this story could shed lights on tha t.If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would reallyappreciate the opportunity to speak with you again.Thank you,RattapholRattaphol "Ahn" OnsanilChief of VOA ThaiNIH-002205NIH-002206Sent from my iPhoneFrom: Fauci, Anthony (NIH/NIAIO) [E)Sent : Wed, 5 Feb 2020 00:31:31 +0000To: Messonnier, Nancy (CDC/DDID/NCIRD/0D)Subject : FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive after he drovetou rists from Wuhan, none of whom had exhibited severe symptomsNancy:See yellow highlight below . Did they misquote the CDC?Thanks,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who Is not the original Intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Folkers, Greg (NIH/N IAID) [E) -------- (b)(6)> Sent : Tuesday, February 4, 2020 12:12 PMTo: Fauci, Anthony (NIH/NIAID) [E)_ _____ _,(_b_ )- ,(-6=)Subject : WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan ,none of whom had exhibited severe symptomsFrom: Folkers, Greg {NIH/NIA ID) [E) -------- (b)( > Sent : Monday, February 3, 2020 1:50 PMSubject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus IsExperts Race to Figure Out How Contagiousthe Coronavirus IsNIH-002207The outbreak of novel coronavirus appears more contagiousthan seasonal flu and is on par with SARS in 2002 and 2003,studies sayChina says that as of Saturday there were 4,109 infected people in the city of Wuhan. Photo: chinadaily /ReutersByChao Deng andJeremy PageUpdated Feb. 2, 2020 7:34 pm ETBEIJING-Public-health experts around the world have been crunching numbers about the advance ofChina's dangerous new coronavi rus to estimate how far and fast it could spread.Studies published in recent days say the new virus appears to be more contagious than seasonal flu andon par with the simi lar pathogen behind an outbreak of severe acute respiratory syndrome in 2002 and2003. The new virus' mortality rate, however, is far below that of SARS.China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city wherethe outbreak began. Some scientists estimate based on statistical models that the number could be inthe tens of thousands.As health autho rities race to control the outbreak, they are also scrambling to figure out. based onimperfect data, how the virus is transmitted, the length of the incubation period and the degree towhich people without symptoms can spread the disease.China's health commission says incubation is generally between three and seven days, with the longestperiod being 14 days, and that people can spread the virus before appearing ill. That makes a two-weekNIH-002208NIH-002209quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks,the main screening method at immigration and other checkpoints."For a given level of transmissibility, more asymptomatic transmission makes a disease harder tocontrol," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London.The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China,says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity tospread from infected patients without symptoms to close contacts within about 6 feet.A study led by a researcher from Boston's Northeastern University-using mathematical probabilitymodels based on travel patterns and confirmed international cases-estimated the median number ofinfections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261.Professors at the University of Hong Kong using similar methods published a study in the Lancet onFriday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were stillin the hundreds."We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, saidJonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhannumbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu."Several recent studies published by scientists estimate that each person infected will, on average, infecttwo to three others. Epidemiologists call that the reproduction number .A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests theproblem is dwindling. Estimates of the reproduction number differ widely, with some studies usingprobability models and others based on regression analysis of cases over different time periods .Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the Universityof Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced."In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whomhad exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted thevirus after attending a training session with a colleague from China, according to the company . TheChinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she testedpositive for the new coronavirus.A study published in the New England Journal of Medicine study by Chinese authors including at theChinese Center for Disease Control and Prevention says the virus spread between people as early asmid-December. The researchers analyzed 425 patients, with more than half of the cases linked to theHua nan seafood wholesale market where authorities believe the virus first spread to humans from wildanimals.The researchers started identifying and collecting cases around the start of the year, by interviewingpatients, relatives and other close contacts. They estimated the reproduction number at 2.2 and saidthat the majority of patients weren't hospitalized unti l after five days of being ill.Researchers of recent studies cautioned that even their estimates of the virus' reproduction number arebased on early and incomplete data and only assess its potential to spread before trave l restrictions andother control measures begin. Thereafter, the reproduction number can vary depending on thosemeasures' effectiveness and other circumstances of the outbreak.Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though someoverseas experts have suggested the outbreak might not peak for several weeks.They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as manyother factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn'tspread that fast because there is a widely used vaccine.As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physicalintervention measures, including locking down entire cities and forced quarantine .NIH-002210Recent studies ind icate that stringent control measures will be needed not just in China, but in severalother countries, to curtail the outbreak ."This is unprecedented both in terms of the virus and the control measures that have been put in place,"says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine.- Raffaele Huang, Miho lnada and Ruth Bender contributed to this article.Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy.page@wsj.comCopyright ©2019 Dow Jones & Company, Inc. All Rights Reserved.87990cbe856818d5eddac44c7blcdeb8Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily representmy views nor those of NTATD, NIH, HHS, or the U.S. government .From : Fauci, Anthony (NIH/NIAIO) [E)Sent : Wed, 5 Feb 2020 00:05:35 +0000To: Baden, Lindsey, M.D .Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea(NIH/NIAID) [E] _____ Cb _H_6);Morens, David (NIH/NIAID) [E]Subj ect : RE: favorAtt achment s: ------------- (~b)~(6~).~(b~)~(4)Lindsey:Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail : (b)(6)(b) (6), (b) (4)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Baden, Lindsey, M.D.<lb aden@nejm.org>Sent ; Tuesday, February 4, 2020 3 :35 PMTo: Fauci, Anthony (NIH/NIAID) [E]_ _____ _(,_b)_. .( ,6.")""Cc: Marston , Hilary (NIH/NIAID) [E] _______ C_>b_C_6>) ; Conrad, Patricia (NIH/NIAID) [E]Subject : Re: favorTony (and Hilary),Much apprec iated .Thank you,Lindsey(b)(6)(b) (6), (b) (4). -------NIH-002211From: "Fauci, Anthony (NIH/ NIAID) [E]" --------- (b)(6)Date : Tuesday, February 4, 2020 at 2:16 PMTo: "Baden, Lindsey, M.D." <lbaden@ne jm.o rg>Cc: "Marston, Hilary (NIH/N IAID) [E]"- ---------Cb)( >, "Conrad, Patricia (NIH/N IAID) [ E]" (b) (6)Subject : RE: favorLindsay:TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : -------- (b)(6)(b) (6), (b) (4)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sende r's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Baden, Lindsey, M.D.< lbaden@nejm.org>(b)(6)Se nt: Tuesday, February 4, 2020 12:31 PMTo: Fauci, Anthony (NIH/NIAID) [E] -------- Subject: favor [~Thank you for considering,Lindsey(b) (6), (b) (4)This email message is a private communication . The information transmitted, including attachments, isintended only for the person or entity to which it is addressed and may contain confidentia l, privileged,and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, ortaking of any action in reliance upon, this information by persons or entities other than the intendedrecip ient is unauthorized by the sender and is proh ibited. If you have received this message in error,NIH-0022 12NIH-002213please contact the sender immediately by return email and delete the original message from allcomputer systems. Thank you.This email message is a private communication . The information transmitted, including attachments, isintended only for the person or entity to which it is addressed and may contain confidential, privileged,and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, ortaking of any action in reliance upon, this information by persons or entities other than the intendedrecipient is unauthorized by the sender and is prohibited. If you have received this message in error,please contact the sender immediately by return email and delete the original message from allcomputer systems. Thank you .From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 22:59:29 +0000Lane, Cliff (NIH/NIAID) [E)RE: favorThanks. Safe trave lsAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Lane, Cliff (NIH/NIAID) [El -------- (b)( >Sent: Tuesday, February 4, 2020 4:31 PM -------=-:~ TCoc:: MFaaursctio, nA,n thHoilnayry ((NNIIHH//NNIIAAIIDD)) [[EEll .-=-=-=-=-=-=-=-(=-b)(6~-)( b)=(6) Subject: Re: favor(b) (6), (b) (4)On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E]- -------- CbH6J>w rote: (b) (6), (b) (4)NIH-002218On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NIH/N IAID) [E] --------- (b)(6) wrote:Anthony S. Fauci , MDDirector. Thanks.National Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301) 496-4409E-mail -------- (b)(6)(b) (6), (b) (4)The information in this e-mail and any of its attachments is confidentialand may contain sensitive information . It should not be used by anyonewho is not the orig inal intended recipient. If you have received this emailin error please Inform the sender and delete it from your mailbox orany other storage devices . The National Institute of Allergy andInfectious Diseases (NIAID) shall not accept liability for any sta tementsmade that are the sender 's own and not expressly made on beha lf of theNIAID by one of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm .org>Sent : Tuesday, February 4, 2020 3:35 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc: Marston, Hilary (NIH/NIA ID) [E] >; Conrad,Patricia (NIH/N IAID) [E] (b)(6)Subject : Re: favorTony (and Hilary), Much appreciated. -------~-~-~-=-(b -)(6),( b)(4) Thank you ,LindseyFrom: "Fauci, Anthony (NIH/ NIAID) [E]"Date: Tuesd ay, February 4, 2020 at 2:16 PMTo: "Baden, Lindsey, M.D." <lbaden@nejm.org >(b)(6)>Cc: "Marston, Hilary (NIH/N IAID) [E]" CbH6J ...:--==========~;;- .."Conrad, Patricia (NIH/NIA ID) [E]" ---------- Cb)(6) Subject: RE: favo rNIH-002219Lindsay:TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7 A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX : (301) 496-4409E-mail: (b)(6)(b) (6), (b) (4)The information in this e-ma il and any of its attachments is confidentialand may contain sensitive information . It should not be used by anyonewho is not the original intended recipient. If you have rece ived this emailin error please inform the sender and delete it from your mailbox orany other storage devi ces. The National Institute of Allergy andInfectious Diseases (NIAID) shall not accept liability for any statementsmade that are the sender's own and not expressly made on behalf of theNIAID by one of its representatives .From: Baden, Lindsey, M.D.< lbaden@ne jm.or g>Sent: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------~--~--- (b)(6=)> Subject: favorTonThank you for considering,Lindsey(b) (6), (b) (4)This email message is a private communication. The information transmitted,including attachments, is intended only for the person or entity to which it isaddressed and may contain confidential, privileged, and/or proprietarymate rial. Any review, duplication, retransmission, distribut ion, or other useof, or taking of any action in reliance upon, this information by persons orentities other than the intended recipient is unauthorized by the sender andis prohibited. If you have received this message in error, please contact thesender immediately by return email and delete the original message from allcomputer systems. Thank you.NIH-002220This email message is a private communication. The information transm itted,including attachments, is intended only for the person or ent ity to which it isaddressed and may contain confidential, privileged, and/or proprietarymater ial. Any review, duplication, retransmission , distribution, or other useof, or taking of any action in reliance upon, this informa tion by persons orent ities other than the intended recipient is unautho rized by the sender andis prohib ited. If you have received this message in error , please contact thesender immediately by return email and delete the original message from allcomputer systems. Thank you.(b) (6), (b) (4lNIH-002221From:Sent:To :Subject:Bob:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 21:28:48 +0000Seder, Robert (NIH/VRC) [E](b)(6)(b)(6) I am drowning here in ------------------------ coronavirus. Hope to talk to you soon.Best,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX : (301) 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.NIH-002222From :Sent :To:Subj ect :Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 21:0 1:39 +0000Conrad, Patricia (NIH/NIAID) [E)FW: Media Request: CBC NewsFYIAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Adam Miller <adam.miller@cbc.ca>Sent : Tuesday, February 4, 2020 3:5-5- -P-M-- -~~ To: Fauci, Anthony (NIH/NIAID) [E)- -------- (b)(6) Subject : Media Request: CBC NewsHi Dr. Fauci,I'm a senior writer with Canada's public broadcaster, CBC News, and I'm working on a national featurestory about the containment efforts of the coronavirus outbreak and what future scenarios could bepossible with the coronavirus globally.You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a fewminu tes by phone to talk about the possibi lity and implications of the outbreak becoming endemic.Would it be possible to speak briefly by phone this week? I would only need a few minutes of your timeand your expertise would be very beneficial for Canadians in the ir understand ing of this story .Thanks very much,AdamAdam MillerNIH-002223Senior Digital WriterCBC NewsDesk: 416-205-5719Cell: (b)(6)Twitter : @adamsmillerNIH-002224From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 20:46:18 +0000(b)(6)Subject: FW: favorAttachments :CbH6).CbH4J Thanks.Anthony S. Fauci , MDDirector(b) (6), (b) (4)National Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : Cb) (6)FAX : (301 496-4409E-mail : Cb) (6)(b) (6), (b) (4)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Baden, Lindsey, M.D.<lbaden@nejm.org>Sent: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '-==-=-==-=--~~ (b=)=(=6-)'!-=-,Cc: Marston, Hilary (NIH/NIAID) [E] Cb)( ; Conrad, Patricia (NIH/NIAID) [E)Subject: Re: favorTony (and Hilary),Much appreciated .Thank you,Lindsey(b)(6)-------(b)- (6), (b) (4)From: "Fauci, Anthony (NIH/NIAID) [E]" --------- (b)(6) Date: Tuesday , February 4, 2020 at 2:16 PMTo: "Baden, Lindsey, M.D." <lbaden@nejm.org>Cc: "Marston, Hilary (NIH/NIAID) [E]" ----------Cb)( >, "Conrad, Patricia (NIH/NIAID) [ E]" (b) (6)Subject: RE: favorNIH-002225Lindsay:TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail : (b)(6)(b) (6), (b) (4)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or igina l intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Baden, Lindsey, M.D. <lbaden@nejm .org>Sent : Tuesday, February 4, 2020 12-:3-1- P-M- --=---c-c= To: Fauci, Anthony (NIH/NIAID) [E] ______ Cb _H_6)Subject : favorTonThank you for considering,Lindsey(b) (6), (b) (4)This email message is a private communication . The information transmitted, including attachments, isintended only for the person or entity to which it is addressed and may contain confidentia l, privileged,and/or proprietary material. Any review, duplication, retransmission, distribution, or othe r use of, ortaking of any action in reliance upon, this information by persons or entities other than the intendedrecipient is unauthorized by the sender and is prohibited . If you have received this message in error ,please contact the sender immediately by return email and delete the original message from allcomputer systems. Thank you.This email message is a private communication. The information transmitted, including attachments, isintended only for the person or entity to which it is addressed and may contain confidentia l, priv ileged,and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, ortaking of any action in reliance upon, this information by persons or entities other than the intendedrecipient is unauthorized by the sender and is prohibited. If you have received this message in error,please contact the sender immediately by return email and delete the original message from allcomputer systems. Thank you.NIH-002226From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 19:36:10 +0000Cassetti, Cristina (NIH/NIAID) [E]Subject: FW: Delivery Status Notification {Failure)Please t ake a look and handle.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone (b) (6)FAX: (301 496-4409E-mail : (b)(6lThe information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Robert Knobler Cb) (6) >Sent : Tuesday, February 4, 2020 1:-36- -P-M-- -~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)Subject : Fwd: Delivery Status Notification (Failure)------- --- Forwarded message -------- - From: Mail Delivery Subsystem -------------=""''"'(b")(- 6)= "Date: Tue, Feb 4, 2020 at 1:30 PMSubject : Delivery Status Notification (Fai lure)To: (b)(6)?•NIH-002231Address not foundYour message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail.The response fr om the remote server was:550 #5 . 1 . 0 Address r e j ected .------- --- Forwarded message -------- --From: Robert Knobler Cb) (6)Toi (b)(6) ----------- Cc:Bee:Date: Tue, 4 Feb 2020 13:29:23 -0500Subject: Potential Coronavirus ProphylaxisDear Dr. Fauci,You likely do not recall meeting me when I was looking at potentialfellowships in 1978, however, I never forgot your enthusiasm. I wentout to San Diego and worked with Mike Oldstone between 1979 and 11984.I did study a mouse coronavirus while there, mouse hepatitis virus(MHV) . I focused on genetic resistance, and eventually described amouse locus for susceptibi lity, which coded for the MHV receptor. Onto the present problem of human coronaviruses, Vaccines will take along time for the current crisis. The angiotens in convertin enzyme 2receptor has been ident ifed as the relevant human coronavirusreceptor. I am writing to suggest the investigation of ARBs aspotential blocking agents to either reduce or completely blockinfection. Perhaps this can be checked. There may sti ll be sufficientuntai nted suppl ies of ARBs, such as irbesar tan, available , orproduction can be scaled up, if this truly is the eve of a pandemic .Wish ing you success in th is endeavor. I am willing to cont ribu te inany way I can. Please feel free to contact me by e-mail or my cellphone .I did do clinical trial while with Mike, and then when I joined theNIH-002232neurology faculty of Jefferson in Philadelphia. I have been out on myown since December 1998, but I have never lost my interest in thiswork . I have some novel ideas on how HIV becomes AIDS, as well.All the Best,Robert L Knobler , MD, PhD(b)(6)(b)( CellNIH-002233From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Tue, 4 Feb 2020 15:54:25 +0000To: 00~Subject : FW: STAT: Quick retract ion of a faulty coronavirus paper was a good momentfor science http:/ /bit.ly/389QguMHeather:As per our recent conversation. This is your story (see below).Best,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who Is not the original Intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .The WatchdogsQuick retraction of a faulty coronavirus paperwas a good moment for scienceBy Ivan Oransky and Adam MarcusFebruary 3, 2020NIH-002237- -- ----• ,Hyacinth Empinado/STATAs fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory newpaper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted.Titled "Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag," thepaper claimed to find similarities between the new coronavirus and HIV, the virus that causes AIDS. Theuse of the word "uncanny" in the t itle, together with "unlikely to be fortuitous" in t he abstract, led someto th ink that the authors were suggesting the virus had somehow been engineered by humans.The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except thatit wasn't.The paper was almost immediately withdrawn, but not before plenty of handwringing from researcherswho complained that the appearance of such shoddy work on a preprint server without vetting by peerreviewers is precisely why the hoary old model of science publishing is better at keeping junk scienceout of the literature.Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to themenace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army ofpeer reviewers. And when these publications publish bad or erroneous research, it can take months oryears for the papers to be corrected or retracted - if they ever are.In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell,commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were atmost a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers aboutcoronavirus. Later Saturday, the authors commented on their paper, saying they were withdrawing it .And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors .They intend to revise it in response to comments received from the research community on theirtechnical approach and their interpre tation of the results."All of that happened before a single news outlet with any reach covered the paper, as best we can tell.But none of it was quite fast enough for some critics. "This is why preprints can be bad," said onescient ist on Twitte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints."What bugs me about this preprint is that had this manuscript undergone legitimate peer review, theseflaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories andfear surrounding this outbreak," Shiloh cont inued.History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bitmisplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet,one of the world's leading peer-reviewed medical journals. Other examples - including a paper by anNIH-002238NIH-002239intelligent design advocate questioning the validity of the second law of thermodynamics as it pertainedto evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year.Preprints can fill a void in times of rapidly changing scienceAnd even when peer-reviewed jou rnals do realize they've been had, retractions can take months oryears. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV didnot cause AIDS. We could go on, and the list includes papers that have never even been corrected.Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has aperfunctory screening process - sometimes acknowledge that journals have had to speed up theirgame to meet the pressures of an outbreak like coronavirus, or SARS in the early part of this century.Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said onTwitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers.Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed.Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly."Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The CoronavirusRace."Publishers have been looking for ways to score points against - and shut down - preprints for at leasthalf a century . Journals have speedily published a number of important papers on the new coronavirusalready, no doubt. Publishing industry champions are often quick to say that speedy peer review doesnot mean sloppy peer review - even in cases that requ ire massive correct ions.It now turns out that one of the world's leading peer-reviewed medical journals, the New EnglandJournal of Medicine, published a lette r last week about apparent coronavirus transmission from anasymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed,or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewedjournal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correctthe record.We'll see whether peer-review champions, who are often unwilling - with some notab le and welcomeexceptions - to acknowledge how slow and ineffective correction in science can be, note this apparentfailure of one of their gatekeepers. Doing so might, after all, make some people question the expensivesubscript ion deals universities agree to with publ ishers, as well as the article processing charges that canrun into the thousands of dollars for open access publications.Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to theexisting process that they can't admit its fl aws - or that it might be a good idea to also embracepreprint servers that could upend their business models. Just like in politics, maybe it's time to agreethat the publishing process is a messy one, and stop using single episodes, free of context, to scorepoints against one's rivals.This article has been updated with information about a flawed report in the New England Journal ofMedicine.Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily representmy views nor those of NIAID , NTH, HHS, or the U.S. government.From:Sent:To:(NIH/NIAID) [E]Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 15:03:33 +0000Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, EmilyCc: Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert(NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E]Subject: Universal coronavirus vaccineAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301) 496-4409E-mail: (b) (6)(b) (5)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .NIH-002240From:Sent:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 14:32:42 +0000To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID)[E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]Subject: FW: CoronavirusAtt achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx,JVP200011( 1). pdfFYI. Confid enti al for nowAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : Cb()6 )FAX: (301 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Howard Bauchner <Howard.Bauchner@jamanetwork.org>Sent : Tuesday, February 4, 2020 9:19 AM ------ -==-- To: Fauci, Anthony (NIH/NIAID) [E] (bH >Subject: FW: CoronavirusTonySee attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly tomention it on Thursday - thought you should see it.HCBFrom: Howard BauchnerSent: Tuesday, February 04, 2020 7:23 AMTo: Annette Flanagin <Annette.Fla nagin@jamanetwork .org>; Christiansen, Stacy<stacy.christ iansen@jama-arch ives.org>; Christopher Muth <Christopher . M uth@jama network .org>;Demetrios Kyriacou <Demet rios.Kyriacou@iamanetwo rk .org>; Edward Livingston--------------- CbH6>>F;o ntanaros, Phil <phil.fontanar osa@jama-archives.org>; Go I u b, Robert <robert.golu b@jama-a rchives.org>; Gregory CurfmanNIH-002241<Gregory.Curfman@jamanetwork.org >; howard.bauchner@jama-archives.org ; Jody Zylke<Jody.Zylke@jamanetwork .org>; McDermott, Mary (b)(6)>; Mike Berkwits<michael.be rkwits@jamanetwork .org>; (b)(6); Anne Cappola------------(b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark <David.Mark@ jam an et work .or g >; Demetrios Kyriacou <Demetrios.Kyr iacou@jamanetwork.o rg>; DerekAngus (b)(6)>; Feero, Greg CbH >; George O'Connor(b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) =====-~;"""'."' (b)(6); Joynt Maddox, Karen (b)(6) PreetiMalani (b)(6)>; Robert Golub <Robert.Golub@jamanetwo rk.org>; Saitz, Richard(b)(6) Schrag, Deborah,M.D. (b)(6)Tom Cole (b)(6)>; Winkel mayer, Wolfgang C. (b)(6);Armstrong, Katrina,M.D. (b)(6); Cutler, David (b) (6); Eric--- (b)(6J>; Goldman,L ee~ -.:-:=======~~ ':-:---:::--~==(b)=(6)=Jo=hn ~Wo-n-g~~ E u Li (Div Head, Med Dep..t.). ..:.c========~~,;-" >; Josh Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant,Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' ------=--:-:-= (b)(6); Steven E. Nissen (b)(6)>; Vokes,Everett [MED] (b)( Zeke ----=-.========~--------===========~--- Em an u e I (b)(6)>; Andy Josephson (b)(6)-----.=======~~------ (b)(6) Bonow, Robe_rt, .M:..D._. _..!====(=b)~(6)~ ~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH ---------- (b)(6) =====->_; D;i_sis_, N._o,ra; _ _._:: ::======~::(b;):(6.;).;>.-; .F- re=d R-i-vara, MD (b)(6); Ongur, Dost;- :R:"i:t.-a--=R--ed-:b--:e--rg- ,-:M--:-D=.-:::::::==~ (b)(6l)>; Shinkai, Kanade(b)(6)======== (~b)- (6~)Subject : CoronavirusSo a quick update.Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. Theyworked on it this weekend - thanks to both .Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemic- but is definite lyrelated. Going up this week.- it will be published on Friday. A big thank you to Phil and Derek.A Rl has also been accepted - it wi ll go up Thursday.I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to processmanuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) andEd have been a big help.As we have done in the past everything wi ll be free to the world.NIH-002242I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony- as I have said many times - is a national treasure.(b) (4)All that said we are definitely interested in novel research report (many can be research letters) . Just letme know .HCBHoward Bauchner, MDEdito r in Chief, JAMA and The JAMA NetworkEmail: howard.bauchner@ jamanetwork.orgTelephone: 312-464-2400Please respect the confidential nature of this email.For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinterviewsNIH-002243From:Sent:To:Cc:Subject :Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 14:09:40 +0000Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E]Haskins, Melinda (NIH/NIAID) [E);NIAID OD AMRE: Thanks and filmingI am leaving it up to you all to determine what is doable, feasible and/orappropr iate . We can discuss at our OD AM meeting .Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave rece ived this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6)Sent: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]-_ -_-_-_-_-_~ = C_Hb_ ; Conrad, Patr icia (NIH/NIAID) [E)(b)(6)>Cc: Haskins, Melinda (NIH/NIAID) [E) _______ CbH_.>; NIAID OD AM<NIAIDODAM@niaid.nih .gov>Subject: RE: Thanks and filmingJust to kee in mind: (b) (4), (b) (5)(b) (4), (b) (5)From: Fauci, Anthony (NIH/NIAID) [E] _______ (b)(.6..),Sent: Tuesday, February 4, 2020 6:42 AM -------~~ To: Conrad, Patricia (NIH/NIA IO) [E)- --------- (b)(6)>; NIAID OD AM <NI A ID OD AM@ n i aid . n i h, gov>Cc: Haskins, Melinda (NIH/NIAID) [E] -------- (b)( >Subject : RE: Thanks and filmingNIH-002244OKFrom: Conrad, Patricia (NIH/NIAID) [E]- ------- (b)(6)> Sent: Tuesday, February 4, 2020 6:35 AM(b)(6)To: NIAID OD AM <NIAIDODAM@niaid.nih.gov>Cc: Haskins, Melinda (NIH/NIAID) [E] --------- Subject : Fwd: Thanks and filmingFor discussion. (b) (4). (b) (5) ------------------------Sent from my iPhoneBegin forwarded message:From: Janet Tobias <janet@ikanamed ia.com>Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> -:-:-:.===========--=-=-= Cc: "Robinson, Whitney (N.I.H../_.N;_I.A ID). .:[.C..J:,"_ :_.===~:;;;------- (b)(6) "Barasch,Kimber I y (NIH/NIAID) [C]" CbH6)>Subject: Re: Thanks and filmingJanetSent from my iPhoneOn Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE]--------- CbH > wrote:Just called you . sorry crazy morningCall me a .__ Cb)(6_) they can pull me from a meeting _____Patricia L. ConradPublic Health Analyst andSpecial Assistant to the DirectorNat ional Institute of Allergy and Infectious DiseasesNIH-002245(b) (4)The National Institutes of Health31 Center Drive, MSC 2520- Room 7A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statement made that are sender 's own and not express ly made on behalf ofthe NIAID by one of its representatives.From: Janet Tobias <janet@ikanamedia.com>Sent: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) ---------------~-=-- CbH6J> Subject: Re: Thanks and film ingPatty can I call you quickly about something-wil l take 3 minutes.Sent from my iPhoneOn Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID)[E] CbH6Jw> rote:It's been super busy. Will group with others tomorrowand get back to you.Sent from my iPhoneOn Jan 30, 2020, at 7:51 PM, Janet Tobias<ianet@ikanamedia .com> wrote :Hi Patty: Thanks for arranging thephone call. CbH4)(b) (4)NIH-002246Never a dull moment in your world!JanetNIH-002247(b) (4)From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 13:58:53 +0000Sylvia BurwellSubject: RE: Travel restriction policyThanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises.It was tough , but we got it right.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Sylvia Burwell (b) (6)Sent: Tuesday, February 4, 2020 8:3-2- A-M- -- ::;..,..-,= To: Fauci, Anthony (NIH/NIAID) [E] CbH6J>Subject: RE: Travel restr iction policyTony,Thanks so much for sending this AND for your very valuable time on Sunday.Our students that returned last week are in self-quarantine ...let me know if I can be helpful to you in any way.Best,SylviaFrom: Fauci, Anthony (NIH/NIAID) [E] ______ Cb_H_6JSent: Monday, February 3, 2020 7:04 PMTo: Sylvia Burwell Cb()6 )Subject : Travel rest riction policyNIH-002248EXTERNAL EMAIL : Use caution with links and attachments.Sylvia:You probably already have this information, but here is the official policy as peour recent discussion (see link).https :// china. usembassy-ch i na .o rg. cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonimm igra nts-bof-persons-who-pose-a-risk-of-transm itti ng-2019-novel-coronavi rus/Best regards ,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .NIH-002249From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 202013:07:15 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: FW: Phone interview request from Seoul, KoreaLet us di scuss.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail Cb) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: The Scoop tbs eFM ------------ (b)(6)Sent : Tuesday, February 4, 2020 6:0-6- -A-M-- -~~ To: Fauci, Anthony (NIH/NIAID) [E)- -------- (b)(6) Cc: (b)(6)Subject: Phone interview request from Seoul, KoreaHello, Dr. Anthony Fauci.This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea.We deliver local and international trend ing news to English speaking listeners around the world .We'd like to invite you to talk with us on the phone for a special interview regarding the novelcoronavirus outbreak.If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturday thiswee k, ORsometime betwee n 9:30 and 10:30 am next Monday, please let us know.And if you're not available for the given time, please also let us know other times feasible for you.The interview will run for about 10 minutes and you'll get your questions in advance.If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated.NIH-002250NIH-002251I look forward to hearing from you soon.Thank you very much .Seyoung LeeFrom:Sent:To:Subject:Attachments :Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 13:05:59 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: 2019-nCoV: potential infection on CD4 cells.Insert positions in HIV gp120.pdfPlease have someone respond to this person.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX : (301 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: (b) (6)Sent: Tuesday, February 4, 2020 2:07 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E)- ------- (b)(6) Subject : 2019-nCoV: potential infection on CD4 cells.Dear Dr. Fauci,As you reali zed the Indian resea rcher published a paper few days ago entitled "Uncann ysimilarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I. gp120 and Gag", whichwas latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL onlinecalcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1 ", "2", and "3"originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on thespike protein of both bat and 20 19 corona virus (page 4 and 6). These insertions are potentialCD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2binding domain (both SARS and 2019 coronavirus targetACE-2, page 5 and 6). In another word,the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cellstoo (like HIV, see page 6) !It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating theirCD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine afterobta ining Spike protein of 20 19-nCoV shall examine its interaction with CD4.NIH-002252Thank you for your immediate attention. Please keep me anonymous.God bless us,NIH-002253(b)(6JFrom:Sent:To:Subject:Francis:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 12:36:50 +0000Collins, Francis (NIH/OD) [E]names for WHO working groupDerek Kan, Acting Deputy Director of 0MB and a member of the President'sCoronavirus Task Force called me last night and in a very nice way said he wouldlike to send me a list of names for consideration to be on the working groups toexamine the evolution of the nCoV. He worked as an executive in biotech priorto joining the USG and knows these individuals well. They are all people that weknow and so I am just passing them on to you for our consideration.Thanks,TonyAnthony S. Fauci, MDDirector(b) (5)National Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX : (301 496-4409E-mail : (b)( 6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the origina l intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its represe ntatives .NIH-002254From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 11:43:36 +0000Conrad, Patricia (NIH/NIAID) [E)Subject: FW: REQUESTF ORA TV INTERVIEWO N WION TV INDIALet us discuss.From: Latika Chugh {WION) <latika.chugh@zeemedia.esselgroup.com>Sent: Tuesday, February 4, 2020 5:15 AMTo: Fauci, Anthony (NIH/NIAID) [E]-------= (b-)c(c-6-)=Cc: Wion Guest Relations <wion.guestrelations@zeemedia.esselgroup.com>Subject: REQUESTF ORA TV INTERVIEWO N WION TV INDIADear Anthony S. Fauci,M.D., NIAID DirectorGreetings from WION!World Is One News (WION)is an international English news channe l from the Zee Med ia Group,Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India',presenting its own perspective on internationa l issues of critical significance. WION is thepreferred channel for most opinion makers across the world as they happily attend our showsbringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia,The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore andSouth Africa etc.WION's shows have featured Indian Political scenario & global leaders speaking on issues facingtheir country and the world in general.I would like to request for your time for an interview with us anytime soon today for 10-15minutes. We usually conduct Interview via Skype. Request you to share your Skype Id.It's regarding CORONAVIRUS.Please let us know when is the best time for you to join us via Skype. Waiting for yourconfirmation.CLICK HERE TO WATCH WION LIVE:https://www .wionews.com/live-tvLive TV, News I wionews.comNIH-002255lNIH-002256© 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved.www .wionews. comLook fo1ward hearing from you .RegardsLatika ChughWION TV , IndiaZee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and isintended for use only by the addressee. Zee Media Corporation Ltd. accepts no responsibility for anymistransmission of, orinterference with, th is communicationFrom:Sent:To :Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 03:02:57 +0000Shalimar AdornoCc:Subject :Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJRE: Message from Dr. Jim Yong KimShalimar:Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due tothe coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied hereand at (b)(6) to squeeze in a time that works for Jim and me. Thank you.Best regards,TonyFrom: Shalimar Adorno (b)(6)Sent : Monday, February 3, 2020 6:33 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)(6) Subject : Message from Dr. Jim Yong KimGood evening Dr. Fauci,I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow.Can you please advise if you have any availability?Kindly,Shalima r AdornoAssistant Vice PresidentGloba l Infrastructure Partners1345 Avenue of the Americas. 30th FloorNew York, NY 10105T (b) (6).___ __ (=b)~(6=)NIH-002257From:Sent:To:Subject:Anthony S. Fauci , MDDirectorFauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 01:14:05 +0000Collins, Francis (NIH/OD) [E]RE: CoronavirusNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)(b) (5)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Collins, Francis (NIH/OD) [E] --------- (b) (6) >Sent : Monday, February 3, 2020 7:26 PM -------~~To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ________ _.Subject: FW: CoronavirusFrom: Shapiro, Neil (NIH/OD) [E] (b)(6)Sent: Monday, February 3, 2020 6:02 PM ------~= To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E]CbH6l;J ohnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz,.....-.-.- :---:---""."':"'"""".""".:--:":===:..--__;--=--=~-Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E](b)(6)Cc: Shaya, Cecile (NIH/OD) [E) --------- (b)(6)Subject: RE: CoronavirusNIH-002258(b) (5)From: Shapiro, Neil (NIH/OD) [E]Sent: Monday, February 3, 2020 4:05 PM-----~~To: Collins, Francis (NIH/OD) IE] (b)( >; Tabak, Lawrence (NIH/OD) [E](b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6)>; Wolinetz,Carrie (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E](b)(6)Cc: Shaya, Cecile (NIH/OD) [E] -------- (b)(6)Subject: RE: Coronavirus(b)(S)From: Collins, Francis (NIH/OD) [E] (bH6J>Sent : Monday, February 3, 2020 1:48 PM -----~~ To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E](bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz,Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E](b)(6)Cc: Shaya, Cecile (NIH/OD) [E) -------- (b)(6)Subject: RE: CoronavirusNIH-002259(b)(5)FCFrom: Shapiro, Neil (NIH/OD) [El Cb)( >Sent: Monday, February 3, 2020 11:33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E]CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz,Carrie (NIH/OD) [E] CbH6)>H; allett, Adrienne (NIH/OD) [E](b)(6)Cc: Shaya, Cecile (NIH/OD) [E]Subject: CoronavirusImportance: HighNeil(b)(6)>NIH-002260(b)(5)From:Sent:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 01:08:37 +0000To: Kai Kupferschm idt ------- --=~ Cc: Greg Folkers (b)(6) ;Billet, Courtney (NIH/NIAID) [E];Conrad,Patricia (NIH/NIAID) [E]Subject: RE: coronavirus quick questionKai:Error in my statement to you. I meant to say that " ...... most t ransmissions occurfrom someone who is symptomatic" - not asymptomatic. I am really tired . Notmuch sleep these days.Best,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone: (b)(6)FAX: (301 496-4409E-mail : (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.From: Kai Kupferschmidt ---------- (b)(6) Sent: Monday, February 3, 2020 7:37 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------ =--c=Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b~)(':.a; iBillet, Courtney (NIH/NIAID) [E]<billetc@niaid .nih .gov>Subject: Re: coronavirus quick questionThanks Tony,this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imagineyour workload at the moment. I will include comment from you now .BestKaiNIH-002261On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....__ ____ (b_H_6.)> wrote:Sorry that I got to this so late. I have been swamped. I just readyour story in Science. It is unfortunate that they did not interview thepatient. Obviously, this changes the conclusion of the paper. Mycomment: "There1s no doubt after reading [the NEJM] paper thatasymptomatic transmission is occurr ing" was made because there hasbeen a lot of discussion among Chinese investigators thatasymptomatic infection is occurring in Wuhan City and Hubei Province,yet no publication came out and said this. Since th is was the firstpublication supposedly documenting this phenomenon, that is why Ireferred to the paper and made my comment. It is unfortunate thatthis error was published, but it still does not really change anything.Rather than rely on rumors, this evening I telephoned one of mycolleagues in China who is a highly respected infectious diseasesscientist and health official. He said that he is convinced that there isasymptomatic infection and that some asymptomatic people aretransmitting infection . The NEJM paper may be incorrect, butaccording to reputable Chinese scientists , my statement is correct .Having said that, I have been saying for some time that even ifasymptomatic infection occurs, it is very unlikely to be a major driver ofthe outbreak since most transmissions occur from someo ne who isasymptomatic.Best regards,TonyNIH-002262From:Sent:To:Subject :Fauci, Anthony (NIH/NIAID) [E)Tue, 4 Feb 2020 00:37:32 +0000Conrad, Patri cia (NIH/NIAID) [E)RE: Tony and ConronavirusSet up a caLI for me with Ed HenryAnthony S. Fauci , MDDirectorNational Ins titute of Allergy and Infectious Dise asesBuilding 31, Room 7 A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: (b) (6)FAX: (301) 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. Itshould not be used by anyone who is not the original intended recipient. lf you have received this e-mail in eITorplease inform the sender and delete it from your mailbox or any other storage devices. The National Institute ofAllergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's ownand not express ly made on behalf of the NlA ID by one of its representatives.-----Original Message-----From: Conrad, Patricia (NIH/NIAID) (E] ---------(b-) (6} Sent: Monday , February 3, 2020 12:28- P-M- ---~~ To: Fauci, Anthony (NlH/NlAID) [E] -------- (b)( 6)> ; Folkers, Greg (NlH/NIAID) (E] (b )( 6)Subject: FW: Tony and Conronavirusf irm for Feb 11ASF will you cancel DDCF or do r need to? Please advisePatricia L ConradPublic Health Analyst andSpecial Assistant to the DirectorNational Institute of Allergy and Infectiou:s Diseases The National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)( 6)30 1-496 -4409 faxDisclaimer:The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. Itshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITorplease inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergyand Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and notexpressly made on behalf of the NIAID by one of its representatives.-----Original Message-----From : Katz , Ruth <Ruth.Kat z@aspenin sti tute.org>Sent: Monday , f ebr1.1a1y3 , 2020 12:20 PMNIH-002263To: Conrad, Patricia (NIH/NWD) [E]- --------- (b)( Cc: Katz, Ruth <Ruth.Katz@aspeninstitute.org>Subject: RE: Tony and ConronavirusWe have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Timewould be over lunch. Attendees arrive around 11 :30 to grab lunch. Program sta rts at noon and runs to about II:15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortlybefore noon so we can mike him up.J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run withit. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first.Our comms team is really interested in pushing this --RuthRUTH J. KATZVice President, Aspen InstituteExecutive Director, Health, Medicine and Society Program The Aspen Instituternth.katz @aspeninstitute .org202-736-5827-----Original Message-----From: Conrad, Patricia (NIH/NTAJD) [E] --------(-b)(-6) > Sent: Monday, February 3, 2020 11 :57 AMTo: Katz, Ruth <Ruth.Katz@aspeninstitute.org>Subject: RE: Tony and ConronavirusTf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pmLet me knowPatricia L. ConradPublic Health Analyst andSpecia l Assistant to the DirectorNational Ins titute of Allergy and Infectious Diseases The National Institutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. Itshould not be used by anyone who is not the original intended recipient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergyand Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and notexpressly made on behalf of the NIA TD by one of its representatives.-----Original Mes:sage-----From: Katz , Ruth <Ruth .Katz@aspenin stitute.org>Sent : Monday , Fcbniary 3, 2020 11: 43 A-M-- ----r:,,:,~ To: Conrad, Patric ia (NIH/N IAID) [E] (b)(6) >Cc: Katz , Ruth <Ruth .Katz@aspeninstitut e.org>NIH-002264Subject: RE: Tony and CoruonavirusHi Patty,Thanks :so much and understand comple tely. Can only imagine how crazt::<ly ou all must be.Definitely don't want to do this without Tony. Jf next week doesn ' t work , please send some potential options.Getting a room can be the real challenge here. So I'd like to at least reserve space and cance l if need be. Also tryingto coordinat e with Ron Klain who is very eager to participat e.Let me know ifI shou ld definitely cance l our space for February 11 or continue to hold for now.Thanks again for everything!RuthRUTH J. KATZVice President, Aspen InstituteExec utive Directo r, Health, Medicine and Society Program The Aspen Instituternth.katz @aspeninstitute.org202-736-5827-----Original Message-----From: Conrad , Patricia (NIH/NTAJD)[ E]- --------(b-)(l>t Sent: Monday , Feb ruary 3, 2020 11 :36 AMTo: Katz, Ruth <Ruth.Katz @aspeninstitute.org >Subject: RE: Tony and ConronavirusHi Ruth - circling back - hope we can make this work - will get back to you in a day or two ....Patr icia L. ConradPublic Health Analyst andSpecia l Assistant to the Dir ectorNational l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. Itshould not be used by anyone who is not the original intended recip ient. If you have received this e-mail in errorplease inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergyand Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and notexpressly made on behalf of the NlAlD by one of its representatives.----- Original Message- ----From: Conrad , Patricia (NlH/NIAID) [E]Sent: Monday , Feb ruary 3, 2020 8:40 AMTo: Katz , Ruth <Ruth .Katz@aspeninstitute.org >Subject: RE: Tony and ConronavirusHi - sorry for the delay - its been insane ly busy.NIH-002265He would love to do this but our schedu le has been changing literally by the minute - so much so that we have hadto cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to dothis and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit.Defer to you tho as to when you want to do your event. Happy to chat more ....Patricia L. ConradPublic Health Analyst andSpecial Assistant to the Dir ectorNational Institu te of Allergy and Infectious Diseases The National Inst itutes of Health31 Center Drive, MSC 2520 - Room 7 A03Bethesda, Maryland 20892(b)(6)301-496-4409 faxDisclaimer:The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. Itshould not be used by anyone who is not the original intended recip ient. If you have received this e-mail in errorplease inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergyand Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender 's own and notexpressly made on behalf of the NlAlD by one of its represen tatives.-----Original Message-----From: Katz , Ruth <Ruth.Katz @aspenin stitute.org >Sent: Friday , January 31 , 2020 5:33 PM- -------~~ To: Conrad , Patric ia (NIH/NTAID} [E] ---------(b-)(6} Cc: Katz , Ruth <Ruth.Katz @aspenin stitute.org>Subject: Re: Tony and ConronavimsHi Patty,Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room.Thank s so much. Hope all is well -RuthSent from my iPhoneOn Jan 27, 2020, at 2:45 PM, Conrad, Patricia (NIH/NIAID) [E]---------------------- (b) ( >> wrote:Hi ruth - will get back to you as soon as we canPatricia L. ConradPublic Health Ana lyst andSpecia l Assistant to the DirectorNational Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health31 Center Drive , MSC 2520 - Room 7A03Bethesda, Maryland 20892(b)(6)301-496 -4409 faxNIH-002266Disclaimer:The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. ltshould not be used by anyone who is not the original intended recip ient. If you have receiv ed this e-mail in errorplease inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergyand Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and notexpressly made on behalf of the NIA ID by one of its represen tat ives.From: Katz , Ruth <Ruth .Katz@aspe ninstitute.org <rnai Ito: Ruth.Katz @aspeninst itute.org >>Sent : Monday , January 27, 2020 4:25 P-M- ------------------~~= To: Comad , Patri cia (NIH/NIAID) [E] __________________ Cb _H_6)Cc: Katz, Ruth <Ruth.Kat z@aspen insti tute .org<mailto:Ruth.Katz @aspen institu te.org>>Subject: Tony and ConronavirusHi Pat ty,Hope all is well and that your 2020 is off to a good, if no doubt, busy start.Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vitiesat the Institute. Hope you can be of help again.1 would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices -hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, formerObama Ebo la czar -- is availab le -- and hope Tony might be as well. Tony and Ron are my first two choices.Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in thelineup .Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance?As always, many thanks -All best ,RuthRUTH J. KATZVice President, Aspen InstituteExecu tive Director, Health , Medicine and Society Program The Aspen Instituteruth.katz @aspeninstin1te.org <mailto:ruth.katz @aspen insti tute.org >202-736-5827NIH-002267From:Sent:To:Cc:Subject :Kai:Fauci, Anthony (NIH/NIAIO) [E)Tue, 4 Feb 2020 00:29:06 +0000GKraei gK uFpoflekersrc~--h m--id--t ---------=---:(b-)(6=) ;B-illet, Courtney (NIH/NIAID) [E] RE; coronavirus quick questionSorry that I got to this so late. I have been swamped. I just read your story inScience. It is unfortunate that they did not interview the patient. Obviously, t hischanges the conclusion of the paper. My comment: "There's no doubt afterreading [the NEJM] paper that asymptomatic transmission is occurring" was madebecause there has been a lot of discussion among Chinese investigators thatasymptomatic infection is occurring in Wuhan City and Hubei Province, yet nopub licat ion came out and said this . Since this was the first publicationsupposedly document ing this phenomenon , that is why I referred to the paperand made my comment. It is unfortunate that this error was published , but it stilldoes not really change anything. Rather than rely on rumors, this evening Itelephoned one of my colleagues in China who is a highly respected infectiousdiseases scientist and health official. He said that he is convinced that there isasymptomatic infection and that some asymptomatic people are transmittinginfection . The NEJM paper may be incorrect , but according to reputab le Chinesescientists, my statement is correct. Having said that , I have been saying for sometime that even if asymptomatic infection occurs, it is very unlikely to be a majordriver of the outbreak since most transmi ssions occur from someone who isasymptomatic.Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone : Cb()6 )FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notNIH-002268accept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Kai Kupferschmidt ------------ (b)(6) Sent: Monday, February 3, 2020 11:47 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E]- ------- CbH6J> Subject : coronavirus quick questionTony,do you have 5 minutes for a quick phone call? Writing a story about the German paper claiming anasymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, soreally wanted to get your reaction on this.CheersKaiKai Kupferschmidtcontributing correspondent "Science"(b)(6)(b)(t wit t er: @kakapeNIH-002269From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 22:28:34 +0000Billet, Courtney (NIH/NIAID) [E]Subject: FW: Coronavirus - reporter 's questionsNIAID in quir ies, please.Anthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Rob Britt Cb) (6)Se nt: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E)-- -----------~-~ CbH6)> Subject : Coronavirus - reporter's quest ionsHi Dr. Fauci: We are updat ing our coronavirus story periodically, keeping it factual and level-headed, andI have seen your comment s on NPR Friday and in the NV Times ove r the weekend, so I hope you couldcomment very briefly for our story :-- What's your expectation fo r whether this will become a pandemic?-- Pandemic does not necessarily equate to a terrible situat ion, comp ared to , say bad flu seasons. What 'syour expectation on the pote ntial severity of t his coronavirus?-- And your suggestion to people in the U.S. who might be very concerned?Thanks for any help you can provide.Cheers,RobRobert Roy BrittTop Write r on Medium in Science & Health.Contr ibutor to OneZero (science) & Elemental (health).Former editor-in -chief of Live Science and Space.com.NIH-002270(b)(6)(b)(6)NIH-002271From:Sent :To:Cc:Subject:Seth:Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 22:27:31 +0000Seth LedermanErbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E]RE: New NHP data on our vaccine for smallpox & monkeypoxI am swamped with coronavirus stuf f, and so I am forwarding this to EmilyErbelding to take a look and respond. Thanks.Best regard s,TonyAnthony S. Fauci , MDDirecto rNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b) (6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may conta in sensitiveinformat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Seth Lederman (b)(6)> ------------- Sent : Friday, January 31, 2020 11:05 AM To: Fauci, Anthony (NIH/NIAID) [E]-- ----------~-~- -- (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypoxDear Tony,I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger.I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented aposter on our further work with TNX-801 (horsepox) as a potent ial vaccine for smallpox andmonkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (nolesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, butlesions on 2/3 animals. More complete information is on the poster attached, which is available on ourwebsite at (https ://conten t .eguisolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/detail/118 6).NIH-002272-We'd welcome the opportunity to discuss the data with you and your team.Best, SethSeth Lederman , MD I Chief Executive OfficerTonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP509 Madison Avenue . Suite 1608, New York, NY 10022Tel ___ _.hl@ I Fax 212 923 5700--------- -'-'""I w"w=w .T o nixPharma.cornNIH-002273(b)(4)(b) (4)From:Sent:To:Cc:Subject:Danielle:Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 22:21:41 +0000Steinberg, DanielleConrad, Patricia (NIH/NIAID) [E);Billet , Courtney (NIH/NIAID) [E)RE: PBS Nature inquiry about CoronavirusMany coronaviruses exist in animal reservoirs, particularly in bats. Rememberthat for the SARS outbreak in 2002, bats infected palm civet cats who were sold inlive/wet markets and the civet cats spread the virus to human . Same for MERS -bats to camels to humans. You ask that there have been animal markets for along time, and so why now. The fact is that this is likely pure chance+/- moreinteractions in the human-animal interface . Animal viruses mutate and most ofthe time the mutations have no significant impact on virus transmission tohumans . Sometimes they mutate and allow single "dead end" transmissions toindividual humans with no efficiency in going human to human and so we getindividual infections and no outbreak as we have seen with HSNl and H7N9influenzas that jump from chickens to humans but do not go from human tohuman. And then rarely, animal viruses mutate and the mutat ion allows themnot only to jump species to humans, but to also efficiently spread from human tohuman . That is what we saw in SARS and now we see this with 2019-nCoV, whichseems to have adapted itself very well to human to human transmission, as perwhat is happening in China.I hope that this is helpful.Best regards,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .NIH-002274From: Steinberg, Danie lle <SteinbergD@th irteen.org>Sent : Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E- _-_-_-_-_- ~~ CbC)6)>Subject: PBS Nature inquiry about CoronavirusHi Dr. Fauci,Hari Sreenivasan of PBS NewsHour suggested I reach out to you with a specific nature question thatwe're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy!We're wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, Chinahas been using animal markets/wildlife trade in these exact ways for a while, so what changed or isdifferent now to cause this illness and outbreak? Any other information you can provide on how animalsare involved wo uld be greatly appreciated.Thank you !Best,Danielle SteinbergDanielle Steinberg I Digital Lead, NATURE I +1 (212) 560-3049 (office)I l I 825 Eighth Avenue 14th Fl. I New York, NY 10019-7435pbs.orq/nature I Facebook I Twitter I lnstagram I YouTubeNIH-002275From:Sent:To:Cc:Subject :Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 16:43:08 +0000Conrad, Patricia (NIH/NIAID) [E)Barasch, Kimberly (NIH/NIAID) [C)FW: Bloomberg Radio 2/4This is Bloomberg and so if we can do this, let us try. If it is too much of a hasslethen say sorry no . Thanks.Anthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda, MD 20892-2520Phone: (b) (6)FAX : (301 496-4409E-mail (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) <jrobinson158@bloomberg .net >Sent: Monday, February 3, 2020 11:23 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)Subject: Bloomberg Radio 2/4Hi Dr. Fauci!I Hope this email finds you well. I'm emailing to see if you can join Tom Keene,Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning asa PH ONER at 8:00am or 8: 15am Et to discuss the Coronavirus. Please let me know ifwe can make this happen. Many thanks!-JameelahJameelah Robinson, M.S.Bloomberg SurveillanceTelevision & RadioBloomberg TV is the world's most-watched business news network, available in morethan 360 million homes worldwide . Watch us live on our website, smartphones, iPadNIH-002276NIH-002277app and the Bloomberg Professional Service.http://Bloombe rg.com/tv/Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), SanFrancisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You canhear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, andTune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audioFrom:Sent:Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 15:17:23 +0000To:(NIH/NIAID) [E]Subject:Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, HughRE: Wuhan nCoV InhibitorsLoren:Thanks for t he note.Best regards,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive , MSC 2520National Institutes of HealthBethesda MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail: (b)(6)(b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who Is not the original Intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Walensky, Loren D.,M.D .,Ph .D. ------------- (b)(6)Sent : Sunday, Februa ry 2, 2020 11:28 PM ------------ -.a-s-= To: Glim cher, Laurie,M .D. (b)(6J>; Fauci, Anthony (NIH/NIAID) [El-------- (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] ----------- (b)(6) Subj ect : RE: Wuhan nCoV InhibitorsNIH-002278(b) (4)PS; Dr. Fauci, ------------------------ (b)(6)Thank you again for any guidance you can provide so that we can try to be of help.Best,LorenLoren D. Walensky, M.D., Ph.D.Professor of PediatricsPrincipal Investigator , Linde Program in Cancer Chemical BiologyAttending Physician in Pediatric OncologyDirector, Harvard/MIT MD-PhD ProgramDana-Farber Cancer Institute/ Harvard Medical School450 Brookline Avenue, LC3216Boston, MA 02215Office: (b) (6)Fax: 617-582-8240Email; (b)(6)Twitter: (b)(6) ------From: Glimcher, Laurie,M.D . --------------- (b)(6) Se nt: Sunday, February 2, 2020 9:33 PMTo: Anthony (NIH/NIAID) Fauci---------,.- (b.H--=6. ) Hugh Jr Auchincloss(b)(6)Cc: Walensky, Loren D.,M.D.,Ph.D.- ------------- (b)(6) Subject: Fwd: Wuhan nCoV InhibitorsTony and Hugh,Loren Walensky is a superb physician -scientist at Dana-Farber -----------------If this is of interest to you, please let me know or contac t him directly.Many thanks,LaurieLaurie H. Glimcher, M.D.President and CEONIH-002279(b)(4)Dana-Farber Cancer Inst ituteRichard and Susan SmithProfessor of MedicineHarvard Medical School450 Brookline Avenue, Dana 1628Boston, MA 02215) §) tel.617.632.2161 faxBegin forwarded message:From: "Walensky , Loren D.,M.D.,Ph.D."Subject: Wuhan nCoV InhibitorsDate : January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." ------------------------------- (b~)(6J=>Hi Laurie. I hope all is well on your end .NIH-002280(b)(6)>(b) (4)(b) (4)Thanks so much,LorenLoren D. Walensky, M.D., Ph.D.Professor of PediatricsPrincipal Investigator, Linde Program in Cancer Chemical BiologyAttending Physician in Pediatric OncologyDirector, Harvard/MIT MD-PhD ProgramDana-Farber Cancer Inst itute/ Harvard Medical School450 Brookline Avenue, LC3216Boston, MA 02215Office: (b) (6)Fax: 617-582-8240Email: (b)(6) ------------ ·The information in this e-ma il is intended only for the person to whom it isaddressed. If you believe this e-mail was sent to you in en-or and the e-ma ilcontains patient informa tion , please contact the Partn ers Compliance HelpLine athttp ://www.partners .org/compli anceline . If the e-mail was sent to you in errorbut does not contain patient info1mation, please contact the sender and properlydispose of the e-mail.NIH-002281(b) (4)From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAID) [E)Mon , 3 Feb 2020 15:12:39 +0000Routh, Jennifer (NIH/NIAID) [ElConrad, Patricia (NIH/NIAID) [ElFW: ANSA news agencyPlease get someone to provide answers for me to send to this person. I do nothave time to do it myself ,Anthony s. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient . If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender 's own and not expressly made onbehalf of the NIAID by one of its representatives .From: Battifoglia Enrica <Enrica.Battifoglia@ansa.it>Sent : Monday, February 3, 2020 5:37 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6)Subject : ANSA news agencyDear Professor Fauci,I am Enrica Battifoglia of the Italian news agency AN SA, I already have had the pleasure tointervi ew you several times at the AIDS world conferences.I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on theANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Italywith over 1.5M contacts each month. I am sure that your clarity and comp etence will be highlyvaluable to put some much-needed order among so many contrasting news and data, and wouldbe much appreciated by our reader s.NIH-002282NIH-0022831) Do the current available data allow to understand the threat level of coronarivus 2019-nCo Vin terms of both lethality and diffusion speed, and about the possible evolution scenarios of thedisease?2) What exactly we know about its modes of transmission, especially from people who do notyet have the symptoms?3) Are the genetic sequences provided by China enough to start working on a vaccine?What are the technical times to develop a working vaccine in terms of scientific research, andwhat are the approx times for the necessary legal certifications, and for industrial production anddistribution?4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in thelast 20 years and in 2009 the virus responsible for the flu pandemic too did come from China:what sort of preventive measures could be practicable to reduce the risk ofrepetition of theseevents?Thank you so much for your time your attention!Kindest RegardsEnrica BattifogliaScience and Technology Head EditorANSA News AgencyII contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono doconsiderarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei DotiPersonali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa emailin mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di nonNIH-002284diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mailappartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA.The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to beconsidered as confidential and protected under the Regulation EU 2016/679 (GDPR), General Data Protection Regulation, aswell as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail inthe absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it,inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone andmay not necessarily reflect those of ANSA AGENCY.From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Mon , 3 Feb 2020 15:10:32 +0000Joe PalcaSubject: RE: Coronavirus vaccineJoe:Thanks for the note. The has nothing to do with the validity of the test. We seethis with other viruses when you look at shedding. When there is a low titer ofvirus, any specific site (in this case a nose or throat swab) may vary betweenpositive and negative even though the person is clearly still infected . It could bethat the virus is there in the throat at one point and cleared at another and comesback again. Alternatively, it may be that the virus is always there, but at differenttiters and at some points it is present below the sensitivity of the test, eventhough the test is in general quite sensitive.Hope that this is helpful.Best regard s,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520Nation al Institutes of HealthBethesda , MD 20892-2520Phone: (b)(6)FAX: (301) 496-4409E-mail (b) (6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the or iginal intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its represent atives .From: Joe Palca <JPalca@npr.org>Sent: Monday, February 3, 2020 9:3-0- -A-M-~ ~ To: Fauci, Anth ony (NIH/NIAID) [E)- ------ (b)( > Subject : FW: Coronav irus vaccineFrom: Joe Pa leaSent: Monday, February 3, 2020 9:13 AMNIH-002285To: 'anthony.facui@nih.gov ' (b)(6)>Cc: 'Deatrick, Elizabeth (NIH/:N-:'.-I"A-.:"1--0::--): -:[-C:'.]",:~"=. ===-----= (b")'"~"( >; Scott Hensley(b)(6)Subject: RE: Coronavirus vaccineHi Tony,It's been nice hearing you on the various press conferences ... can't believe we're still both doing this.Have a question about something Redfield said in Friday in the White House briefing about nCoV. Hesaid using their PCR assay, the virus can be detectable one day, then not the next, then detectab le.I'm curious about this . I see a few possibilities:1. The test isn't as sensitive as CDC hopes2. The sample was taken from different places3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next.4. The virus may be hanging out in the terminal bronchioles, and only pop up to the upperrespiratory system from time to time.Arn I on the right track? Wou ld you have a few minutes today to record an interview with me?JoeNIH-002286From:Sent:To:(b)(6)Mon, 3 Feb 2020 05:45:35 -0500Conrad, Patricia (NIH/NIAID) [E)Subject : Fwd: Interview request (Seoul, Korea)Sent from my iPhoneBeg in forwa rded message:From: ;;'<} ~ '-t (b)(6) >Dat e: February 3, 2020 at 2:29:21 AM EST To: "Fauci, Anthony (NIH/NJAID) [E]' ----------------'=""'("bH"6l '>= Subject: Interview request (Seoul, Korea)Dear Or. Fauc i.I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea.I am the directo r of currunt- issue radio show of TBS and I'd like to have a telephoneinterview with you on my radio program about co ronavirus issue all over the wor ld.As Korea is a very close count·y to China and many people are very concerned aboutthis issue.I would like to hear your opinion as a world authority on this issue.The time for phone interview would be about 6 a.m . at Maryland time and I want toproceed it through an English-Korean interp reter.I would apprec iate it if you could reply to me if you are poss ible.The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim.Respectf ully,Mrs. Hyun- na Cha(b)(6)TBS. Seoul. KoreaNIH-002287From:Sent:To:Subject :Fauci, Anthony (NIH/NIAID) [E)Mon, 3 Feb 2020 03:47:33 +0000Howard SchatzRE: If too busy then pass---l'd understandToo soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than weare now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the samefamily of viruses as SARS.-----Original Message-----From: Howard Schatz ----------- (b~)~(=Sent: Friday , January 31, 2020 8:51 AMTo: Fauci . Anthony (NIH/NIAID) [E] ------ =CsHb-=-6.),Subject: If too busy then pass---T'd understandTony,New Coronavirus: saw you on national news with a dozen others at DT's table yesterday.Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others.What is your cunent thinking on it?Hope all is well, otherwi se.Thanks ,howardNIH-002288From :Sent :To:Subject :Fauci, Anthony (NIH/NIAIO) [E)Mon, 3 Feb 2020 03:45:59 +0000Auchincloss, Hugh (NIH/NIAID) [E]FW: Wuhan nCoV InhibitorsPlease handle this . Thanks .From: Glimcher, Laurie,M.D. -------------- (b)( > Sent: Sunday, February 2, 2020 9:33 PMTo: Fauci, Anthony {NIH/NIAID) [E] ------ (=b)c-(c= >; Auchinclo ss, Hugh (NIH/N IAID) [ E](b)(Cc: Walensky , Loren D.,M .D.,Ph.D. --------------- (b)(6)Subject : Fwd: Wuhan nCoV InhibitorsTony and Hugh,(b)( 4Loren Walensky is a superb physician-scientist at Dana-Farber -----------------If th is is of interest to you, please let me know or contact him directly .Many thanks,LaurieLaur ie H. Glimcher , M.D.President and CEODana-Farber Cancer InstituteRichard and Susan SmithProfessor of MedicineHarvard Medical School450 Brookline Avenue, Dana 1628Boston, MA 02215"--- ~~ @.!.! te l.617.632.2161 faxBegin forwarded message:From: "Wa lensky, Loren D.,M.D.,Ph.D." ------------- (b)(6)> Subject : Wuhan nCoV InhibitorsDate : January 30, 2020 at 7:23:54 PM EST ------------- r;a-.-,--.= To: "Glimcher, Laurie,M.D." --------------- (b)(6)NIH-002289Hi Laurie. I hope all is we ll on your end .Thanks so much,LorenLoren D. Walensky, M.D., Ph.D.Professor of PediatricsPrincipal Investigator, Linde Program in Cancer Chemical BiologyAttending Physician in Pediatric OncologyDirector, Harvard/MIT MD-PhD ProgramDana-Farber Cancer Institute/ Harvard Med ical School450 Brookline Avenue, LC3216Boston, MA 02215Office: (b)(6)Fax: 617-582-8240Email (b)(6)NIH-002290(b) (4)(b) (4)NIH-002291The information in this e-mail is intended only for the person to whom it isaddressed. If you believe this e-ma il was sent to you in error and the e-mailcontains patient information, please contact the Partners Compliance HelpLine athttp: //www .partners .org/complianceline . If the e-mail was sent to you in errorbut does not contain patient information, please contact the sender and properlydispose of the e-mail.From:Sent :To:Subject :Please handle.From: Ulrica MolstadFauci, Anthony (NIH/NIAID) [ElMon, 3 Feb 2020 02:10:49 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: Homozygous for Alpha-1 antitrypsin and coronavirus?(b)(6)> ----------- Sent : Sunday, February 2, 2020 9:07 PM To: Fauci, Anthony _{.N:_IH_/N:,IA__I D_) :.[E..]; -:,-_-.-:J-=-=~=~~= ---(-b)(6)>Cc : Ulrica Molstad _________ C_)b_C_6>)Subject: Homozygous for Alpha-1 antitrypsin and coronavirus?H·I1.I read that you are an expert working for NIAID and that you got interviewed about treatments for thecorona viru s.I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted toshare a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS)with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha-1 anti trypsin is an acute phase reactant and increases in sick people. I have seen that the Alpha-1-antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, eventhought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level ofAlpha-1 antitrypsin is misleading and can result in the physician believing that there is nothing wrongwith the patients function of Alpha-1-antitrypsin.I also guess that critically ill ECMO-treated patients with lung symptoms might benefit from receivingAlpha-1 anti protease inhibitor in addition to other medications given to them. What do you think?I believe that this information can contribute in understanding why some supposedly healthy individualsgets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read .Best regards, Ulrica Molstad, M.D.NIH-002292From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Mon, 3 Feb 2020 00:50:43 +0000James KrellensteinSubject: RE: 2019-nCoV Testing for Public Health LabsJames:Thanks for the heads-up. I will see what I can do.Best,TonyFrom: James Krellenstein ---------- (b)(6) Sent : Sunday, February 2, 2020 7:37 PMTo: Fauci, Anthony (NIH/NIAID) [E) --------. ~Cc: David Barr (b)(6) >; Lord, Aaron (b)(6)Peter Staley ------====~~----- ------------- (b )( 6)Subject: 2019-nCoV Testing for Public Health LabsTony:I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests fromleaders of public health departments and public health practitioners to begin publicly pressuringCDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can performreal time reverse transcription PCR (qRT-PCR) testing for 2019 Novel-Coronavirus (2019-nCoV).Our understanding is that given the public health emergency decla red by HHS, an emergency useauthorization (EUA) from the FDA is required for public health labs to perform their own lab developedtest for 2019-nCoV, even if it is using the CDC's published qRT-PCR protocol and primer/probesequences (htt ps://www .cdc.gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r-detect ion- i nstr uctions . pdf ), and the lab is capable of handling BSL3+ samples.We understand the extreme delicateness of this situa t ion, and also that it is outside of our normalwheelhouse . But given the concerns of our colleagues in the public health sector, we thought it wasimportant to give you a heads up regarding this request .Let us know if there is anyway we can help .Sincerely,James KrellensteinData, Science and Policy CommitteeThe PrEP4AII Collaboration109 S 5th St, Brooklyn, NY 11249(b)(6)NIH-002293James B. Krellensteinhe - him - his(b)(6)(Sent from a mobile device)NIH-002294From:Sent:To:Fauci, Anthony (NIH/NIAID) [E)Sun, 2 Feb 2020 23:54:27 +0000NIAIDODAMSubject:coronavirusAttachments:FW: Invitation for an expert panel webinar on the role of micronutrients and2020.02.02 Expert panel objectives.docxLet us discuss. Probably no.From: (b)(6)> --------------------- Sent: Sunday, February 2, 2020 9:49- A-M- ---,;-. = To: Fauci, Anthony (N IH/NIAID) [E] (b)(6)1>Cc: Peter van-Dael .,,;.__.;. .;...;;...;,_.=== (cb:)":=('6=);'----Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirusDear Dr. Fanci,I would like to address you for an expert panel webinar on the role of micronutrients andcorona virusDue to the new coronavirus outbreak and the rapidly escalating global spread, lots of questionsare raised regarding the role of micronutrients in supporting the immune system. DSM hasreached out to me with a request to organize rapidly a focused expert panel in order toestab lish expert guida nce summarizing key points with respect to the role of micronutrients insupporting our body 's immune response, in light of the current genera l consciousness thatamong other factors nutrition is important in combatting infectious diseases. Peter Van Dael,head of Nutrition Science & Advocacy, is responsible for the coordination of this activity atDSM.I agreed to take on this challenge and therefore intend to organize this expert panel throughwebinar in order to manage the challenges related to busy agendas and travel within the nextweek, if possible. The webinar is expected to last for about 3 hours maxinmm and would befacilitate through the distribution of a short background document I will share in order tofacilitate the discussion.J will try to reach out to you tomorrow by phone in order to review whethe r you would beavailable for this engagemen t and whether you would you have potentia l questions prior toagree ing to participate.With our best regards,Manfred PeterNIH-002295Dr. Manfred EggersdorferProfessor for Healthy Ageing(b)(6)(b)(6)Dr. Peter Van DaelDSM Nutr ition Science & AdvocacyNIH-002296From:Sent:To:(b)(6)Sun, 2 Feb 2020 18:20:17 -0500Carlos del RioSubject:virusRe: [External] RE: Mexican researchers have defined the structure of the CoronaVery inte resting.On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote:(b)(6) sent me this update. Thought you would enjoy. --------- Interesting to see how they view outbreaks .....Coronavirus new s over the weekend was a sma ll net positive (although there wereplenty of nega tives). Encouragingly, doctors appear to be having some successtreating patients with existing antiviral drugs - GILD's remdesivir improved theclinica l con dit ions of a coronavirus patien t in Washington state (WSJ) whileThailand said it had achieved good results using antiviral drugs originally designedfor the flu and HIV (Bloomberg). It's way too early to tell whether these drugs willperfom1 well in other patients (and a vaccine is still some time away) , but theprogress noted in the US and Thail and is positive. The PBOC said it would injectCNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth lywhen they reopen from the New Year holiday (this works out to about CNY150B ofnet incremental liquidity given CNY1.05 T of reverse reports are set to mature onMonday). The gov' t also announced other steps (including waiving equityownership limits for some insurers) aimed to bolstering market confidence . Theglobal corona virus case count cont inues to rise (it now stands at ~ 15K as of Sundaymorning withe death toll north of 300) whi le more travel restrictions are beingimpo sed by governments and companies around the world (Apple said it wouldshutte r all its stores and offices in China until Feb 9). According to a CNBC update ,areas of China responsible for ~80% of GDP and ~90% of exports are set to stayclosed until at least Feb 10.Carlos del Rio, MD.Sent from my iPhoneOn Feb 1, 2020, at 11: 13 PM, Fauci , Anthony (NIH/NIAID) [E]-------- (b) (6)>wrote:I love it! □□NIH-002297-----Original Message----- From: Del Rio, Carlos 4- -----~~ Cb>~<>Sent: Friday, January 31, 2020 10:05 AM ------ --=-= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: Mexican researchers have defined the structure of the CoronavirusThis e-mail message (including any attachments) is for the sole use ofthe intended recipient(s) and may contain confidential and privilegedinformation. If the reader of this message is not the intended recipient ,you are hereby notified that any dissemination, distribution or copyingof this message (including any attachments) is strictly prohibited.If you have received this message in error, please contact the senderby reply e-mail message and destroy all copies of the original message(including attachments).NIH-002298From:Sent:To:Subject :Fauci, Anthony (NIH/NIAID) [ElSun, 2 Feb 2020 22:56:05 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: coronavirusFrom: Dr.h.c. Richard Hajdu ------- (b)( >Sent: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----------~-~-- (b)(6) Subje ct: coronavirusDear Anthony Fauci.I speak hard English so I write to you using google trans lator .I have a cured corona virus cure. I am will ing to provide you . In laboratory conditions you can t ry. Thismedicine can destroy the virus within 12 hours .If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the CzechRepublic. In the city of Brno.Dr. Richard HajduNIH-002299From: Fauci, Anthony (NIH/NIAID) [ElSent : Sun, 2 Feb 2020 22:43:15 +0000To: Cassetti, Cristina (NIH/NIAID) [ElSubject : FW: coronavirus - easy, safe, and likely highly effective treatment.Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf,published article on ozone and ebola 3578-10714-4-PB.pdfPlease handle.From: Robert Jay Rowen (b)( >Sent : Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------- ~(b~)(6) > Subject: coronavirus - easy, safe, and likely highly effective trea tment.Dear Dr. Fauci,I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patientswith coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears.The therapy is ozone. It can be performed, depending on the method, for mere pennies in mater ials. It isnot patentable, so, it lacks profitability needed for some payback for the basic research to get it"approved" .It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5recovered almost immed iately. No sequela. No one has repo rted anyth ing like that.I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed mypractice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, Irecent ly published, might be the solution the world desperately needs for the emerging crisis inresistant infections.I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done toaddress corona virus, which I am try ing to get published. It is not easy. The medical world is vested inPharmaceuticals.I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for thatreason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I amcoming to you about t his as one physicist came to President Roosevelt about harnessing the power ofthe atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you.The first file is a word document I am seeking to get published. Usually, an author will holdup on making material like this public until he get published. However, wi th livesimmediately on the line, we want to alert people that the does exist an available veryinexpensive and extremely safe medical treatment for this and other infections .If you have questions, please contact me here.Sincerely,NIH-002300Robert Ja Rowen , MD(b)(6)www.DrRowenDrSu .comhttp://www . youtube. com/user/Robe rtRowenMDhttps:/ /www.facebook.com/D rRobertJRowen"The doctor of the future will no longer treat the human frame with drugs, but rather willcure and prevent disease with nutrition" , Thomas EdisonHIPAA Notification : This electronic message (includ ing any attachments) isintended only for the exclusive use of the individual to whom it is addressed. This email,including any attachments , is confidential and is legally privileged. If you have receivedit in error please advise the sender immediately by return email and then delete it fromyour system. The unauthorized use, distribution, copying or alterations of this email isstrictly forbidden. If you need assistance please contac (b)(6) Note toPatients : There are inherent confidentiality risks in communicating by email. Whilesafeguards are in place to ensure your privacy, you should not use emailcommunication if you are concerned about any breaches of privacy thatmight inadvertently occur.NIH-002301From:Sent :To:Cc:Subject:Fauci, Anthony (NIH/NIAIO) [ElSun, 2 Feb 2020 22:40:07 +0000Greg Folkers (b)(6))Conrad, Patricia (NIH/NIAID) [ElFW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5FSee below the link that CbH6>senmt e. It is a picture of me briefing President Reagan at the NIHin 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks.From: (b)(6) {N IH/CC/BEP) [El (b)(6)Sent : Sunday, February 2, 2020 5:11 PM ------ ..---.-.-= To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)Subject : RE: Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSFThe oldest one in the batch:https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald-w-reaganand-news-photo/50454084 ?ad ppopup=trueFrom: Fauci, Anthony (NIH/N IAID) [El CbH >Sent : Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6)Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5FfyiFrom: Folkers, Greg {NIH/NIAID) [El --------- (b)(6)Sent: Saturday, February 1, 2020 9:02 PMTo: NIAID OD AM <NIAIDODAM@niaid.n ih.gov>Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5FNIH-002302NIH-002303Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily representmy views nor those of NIAJD , NIH , HHS , or the U.S. government.From: Fauci, Anthony (NIH/NIAIO) [ElSent : Sun, 2 Feb 2020 22:36:41 +0000To: Routh, Jennifer (NIH/NIAID) [E]Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg(NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E]Subject: RE: Fauci/Redfield op-ed for reviewAttachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HMGF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120_EOCCleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docxI have gone over the document and have made a numbe r of t racked changes. In addition, forease of reading I have accepted all the tracked changes and am sending a clean copy. Hencethere are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting allchanges. Please note that the CDC has not announced the 3 additional cases and so dependingon when this goes out we need to make sure that the offic ial number is 11 and not st ill8Thanks !From: Routh, Jennifer (NIH/N IAID) [E] CbHSent: Sunday, February 2, 2020 4 :36 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>S; tover, Kathy (NIH/NIAID) [El(b)(6) >; Folkers, Greg {NIH/NIAID) [El CbH6)>; Conrad, Patricia(NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>Subject: Fauci/Redfie ld op-ed for reviewDr. Fauci -Attached is the draft op-ed for your review. Greg, Hilary and I have added proposed edits in trackchanges. We will send back to CDC/HHS one document with all NIAID edits in track changes. HHS wouldlike to get a draft to the White House at some point this evening.Thanks,JenJennifer Routh [E]News and Science Writing BranchOffice of Communications and Government RelationsNational Institute of Allergy and Infectious Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda, MD 20892Direct (b) (6)Disc laimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not beused by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives.NIH-002304From:Sent :To:Subject:Please handle.Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 19:24:26 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: Specific Questions About CoronaVirusFrom: Rafael C. R. (b) (6)>Sent : Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] ---------------- (.b)-(6-) --..-.= Subject : Specific Questions About CoronaVirusHi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you somemonths ago about the influenza virus differences across regions. I recently t raveled to DC and NY andhad a great time there (before the Corona Virus outbreak)I have some specific questions about the new Corona Virus, and would be very grateful if you cananswer them :1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virusbehavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=OI've used exponential tr end, although it seems to be spreading slower than the expected, I'd like toknow if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spreadexponentially?2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 .Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get preparedfor the worst? Buy water, dry food , stay indoors, withdraw money, etc?Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you,so it means a lot to meThank you,RafaelNIH-002305From:Sent:To:Cc:Subject :Fauci, Anthony (NIH/NIAI0) [E)Sun, 2 Feb 202018:33:43 +0000Liang, Jake (NIH/NIDDK) [E)Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C]RE: FavorThank s, Jake. Mark will contact you directly .From: Liang, Jake (NIH/NIDDK) [E] _______ Cb _>C6bSent: Sunday, February 2, 2020 1:32 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)_C_c_: Mark ..D...y.b;.u_l- ===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E)--------- (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject : Re: FavorHi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clearsome time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear whatthey have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic(not sure whether it is qualified as one yet; if not, pretty close)!! JakeFrom: Anthony Fauci (b)(6)Date: Sunday, February 2, 2020 at 12:20 PMTo: Jake Liang CbH6>>Cc: Mark Dybul CbH6>>",C onrad, Patricia (NIH/NIAID) [E)"----------- CbH6>",B arasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: FavorJake:Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is theformer Head of PEPFAR and the former Director of the Global Fund to Fight AIDS, TB, andMalaria will be at the NIH tomorrow with a scientist who has some very interesting data onhepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Isthere any chance that you can meet with them briefly tomorrow. I believe that you might beinterested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail youto see if you can make this happen. Many thanks.Best regards,TonyAnthony S. Fauci, MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520NIH-002306Phone : (b) (6)FAX: (301) 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the origina l intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .NIH-002307From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 18:02:22 +0000Billet, Courtney (NIH/NIAID) [E]Subject: RE: Seeking comment on Indian paper about new CoronavirusGeeeezFrom: Billet, Courtney (NIH/NIAID) [E] --------- (b)(6)Se nt: Sunday, February 2, 2020 12:53 PMTo: Fauci, Anthony (NIH/NIAID) [E] ------ -(=b-)c(-c6-)=Cc: Marston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E](b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) (6)>; Stover, Kathy(NIH/NIAID) [E]- ------- (b)(6J>; Routh, Jennifer (NIH/N IAID) [E]- -------- (b) ( ·> Subject: Fwd: Seeking comment on Indian paper about new CoronavirusFYI re the paper from the Indian researchers .Talk about trying to put the genie back in the bot tle! Yeesh.From: "Mascola, John (NIH/VRC) [E]" (b)(6)Date : Sunday, February 2, 2020 at 10:39:42 AM ------- ~= To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]"(b)(6) "Hiatt, N is.s ..a- :-(:N -".I'H::-'.:/--:V:--R::~C'): ":["C -:~:]":":==::::::...;___ _,_(b, );.,~6=)> ---------- Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]"-------- (b)( >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru sAlso note the following from the author on the BioRxiv comment section:Prashant Pradhan 8 hours agoThis is a preliminary study . Considering the grave situation, it was shared in BioRxiv as soon aspossible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not ourintention to feed into the conspiracy theories and no such claims are made here. While we appreciatethe criticisms and comments provide d by scient ific colleagues at BioRxiv forum and elsewhe re, thestory has been differently interprete d and shared by social media and news platforms . We havepositively received all criticisms and comments . To avoid further misinterpretation and confusionsworld-over, we have decided to withdraw the current version of the preprint and will get back with arevised version after reanalysis, addressing the comments and concerns . Thank you to all whocontributed in this open-review process .: Authors of the ManuscriptNIH-002308From: Routh, Jennifer (NIH/NIAID) [El (b)(6) _____._. ___Sent : Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El -_-_-_-_--_- -~= C_Hb_6); Hiatt, Nissa (NIH/VRC) (CJ(b)(6)Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [ElCbH6)>B; illet, Courtney (NIH/NIAID) [El CbH6)>S; tover, Kath y(NIH/NIAID) [E) (b)(6)Subject: RE: Seeking comment on Indian paper about new CoronavirusHi Barney -We consulted with HHS and ASF. OCGR is going to send a note to the reporter to decline, noting that thepaper is not peer-reviewed. Please let us know if you receive similar requests.Thanks,JenJennifer Routh [ElNews and Science Writing BranchOffice of Communications and Government RelationsNational Institute of Allergy and Infectious Diseases (NIAID)NIH/HHS31 Center Drive Room 7A17CBethesda , MD 20892Direct: Cb)~Disclai mer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not beused by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete itfrom your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for anystatements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives.From: Graham, Barney (NIH/YRC) [El ----------- (b)( Sent : Saturday, February 1, 2020 2:11 PMTo: Hiatt, Nissa (NIH/VRC) (CJ- ------- (b)( ; Routh, Jennifer (NIH/NIAID) [El (b) ( 6) >Cc: Marston , Hilary (NIH/NIAID) [El _______ C_>b_<_6>J ; Mascola, John (NIH/YRC) [El(b)(6)Subject : FW: Seeking comment on Indian paper about new CoronavirusHi Nissa and Jen,This is one we don't want to answer without high-level input, but wanted you to know about the risingcontroversy .BGNIH-002309From: lssam AHMED <lssam.AHMED@afp.com>Sent: Friday, January 31, 2020 5:27 PM -------- ~= To: Graham, Barney (NIH/YRC) [E] ________ Cb _H_6)Subject : Seeking comment on Indian paper about new CoronavirusDear Dr Graham,I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies forreaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on thispaper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf itsuggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence.Thanks you very much, if you are able.lssam Ahmedlssam AHMEDHealth, Science and Environment Correspondent1500 K St. NW - 20005 WashingtonTel : (202) 414-0521June 24 , 2020Virus death toll nears half a million as cases surge in US, Latin AmericaJoin us on:I) Cl afp.comNIH-002310From:Sent:To:Fauci, Anthony (NIH/NIAID) [E)Sun, 2 Feb 2020 17:13:03 +0000Mark DybulSubject : RE: A connection to jakeMark:Thanks for the note. Sony that l had to cancel. This is Wbite House i11 full overdrive and I am in the middle ofit. Reminiscent of post -anthrax days. I will send an email to Jake today to introduce you. Again , sorry about thecancellation. Hope to see you soon. Regards to Jason.Best ,Tony-----Original Messa.g .".e "--------------~~From: Mark Dybul (b) (6)>Sent: Sunday, February 2, 2020 11 :37 AMTo: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject: A connection to jakeHey tonyKnow you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoomin hen things calm down.We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to shareMondayRealize this is last minute but mig ht it be possible for you to connect me to jake Jiang in case we can squeeze in ameeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)?Jfyou are not comfortable with that 1 could send him a cold caU email mentioning we have shared the data withyou. You were kind enough to introduce us at the nam dinner when (b) (6).Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you asusual.Thanks muchMarkSent from my iPhoneNIH-0023 13From:Sent :To:Cc:Subject:Francis:Fauci, Anthony (NIH/NIAID) [E)Sun, 2 Feb 2020 16:49:35 +0000Collins, Francis (NIH/OD) [E]Tabak, Lawrence (NIH/OD) [E]FW: TeleconferenceDo you have a minute for a quick call?TonyFrom: Jeremy Farrar (b)(6)Sent : Sunday, February 2, 2020 11:28 AMTo: Fauci, Anthony (NIH/NIAID) [E] -------= (b=)(= ; Collins, Francis (NIH/OD) [E](b)( .Cc: Tabak, Lawrence (NIH/OD) [E) --------- (b) (6)>Subject: Re: TeleconferenceTedros and Bernhard have apparently gone into conclave .... they need to decide today in my view. Ifthey do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we mighttake forward .Meanwhile ....https ://www .zerohedge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over art ificia lly-created-b iowea ponFrom: "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>Date : Sunday, 2 February 2020 at 15:30To: Jeremy Farrar CbH6J>, Francis Collins (b) (6)>Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6)Subject: RE: TeleconferenceJeremy:Sorry that I took so long to weigh in on your e-mails with Francis and me. I was onconference calls.Best regards,TonyFrom: Jeremy Farrar (b)(6)>Sent : Sunday, February 2, 2020 7:13 AMNIH-0023 14(b)(5)Cb) (5lTo: Collins, Francis (NIH/OD) [E] (b)(6)>Cc: Fauci, Anthony (NIH/NIAID) ['.:E:-] :.=====~ (b')"( "=', >; Tabak, Lawrence (NIH/OD) [E](b)(6)Subject: Re: Teleconference....R eally apprec iate us thinking through the options ... ---------------- (b)(5From: Francis Collins (b)(6)>Date: Sunday, 2 February 2020 at 12:03To: Jeremy Farrar CbH6)>Cc: "Fauci, Anthony (NIH/N IAID) [E]" --------- (b)(6), "Tabak, Lawrence (NIH/OD) [E]" (b)(6)Subject: RE: TeleconferenceHi Jeremy,Thanks for forwarding these additional reflections from Mike and Bob.FrancisFrom: Jeremy Farrar (b)(6)Sent: Sunday, February 2, 2020 6:53 AMTo: Collins, Francis (NIH/OD) [E] ------- (b..~ . c=6JCc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Tabak, Lawrence (NIH/OD) [E](b)(6)Subject: Re: TeleconferenceThank youSee thoughts overnight from others.NIH-002315(b)(5)~(b) (5)(b) (5)Jeremy(b)(5)NIH-002316From: Francis Collins CbH6)>Date: Sunday, 2 February 2020 at 10:27To: Jeremy Farrar (b)(6) "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IAID) [E]" --------- CbH6), "Tabak, Lawrence (NIH/OD) [E]" (b)(6)Subject : RE: TeleconferenceJeremy,(b) (5)I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let meknow if I can help get through his thicket of protectors.FrancisFrom: Jeremy Farrar (b)(6)Se nt: Sunday, February 2, 2020 4:48 AMTo: Andrew Rambaut (b)( >Cc: R.A.M. Fouchier (b)(6); Fauci, Anthony (NIH/NIAID) [E)(b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~= (b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes(b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=- Paul Schreier (b)(6); Ferguson, Mike(b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:....,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6)Subject: Re: TeleconferenceThis is a very complex issue.lwill:(b) (5)NIH-002317(b)(5)I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed.JeremyFrom: ' Cb(>6)Date: Sunday, 2 February 2020 at 09 :38To: Jeremy Farrar CbH6)J>Cc: f CbH6[>), "Fauci, Anthony (NIH/ NIAID) [E]"CbH~, Patrick Vallance ( CbH6)>",D rosten,Christian" I- --=========~----_;_ CbH~,M arion Koopm_a_n s ..!::::=="='=_:,0_:_:-- C_b H6)J,Edward Holmes r CbH6)jCbH~ , "Kristian G. Andersen" I (b)(6) J, Paul SchreierCbH~ Michael FMedSci ==========::=:~-------:::=======-==:,:,,:;--- (b )( ~ >, Francis Coll ins( Cb)(~CbH~ Josie Gold ing ~=========,,..,_...--------- (b )( 6)jSubject: Re: TeleconferenceDear Jeremey, Ron and all,Thanks for invitin g_m_one the call vesterda . (b)(5) ~(b)( 5)NIH-0023 18Best,AndrewOn 2 Feb 2020, at 08:40, Jeremy Farrar_ _______ C_>b<..6. ) wrote :Thanks RonThoughts on tbat very welcome.On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote:Dear Jeremy and others,This was a very useful teleconference.Thanks for organizing this on such short notice,Kind regardsNIH-0023 19(b)(5)(b) (5)(b) (5)(b) (5)RonRon's noUtfe~s_?:; ,_____________________ 71(bi ,J~i5HJNIH-002320(b)( 5)NIH-002321Van: Jeremy Farrar (b)(Datum : zaterdag 1 februari 2020 om 21:59Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------- C-bH.-.=-6)>, PatrickVallance (b)(6)CC: Christian Drosten (b)(6) "M . Koopmans" -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- (b )( 6), "R.A.M. Fouchier" =========~~--- (b )( , Edward Holmes ========:------ (b)(6)CbH6), Andrew Rambau (b)(6)"Kristian G. Andersen" (b)(6), Paul Schreier(b)((b)(6), "Ferguson, Mike"(b)(5)(b)(6) Francis Collins (b)(6),(b)(6)>, Josie Golding...========= (b:)::(:6:~)--------0nd erwerp: Re: TeleconferenceThank you to everyone for joining.There is clearly much to understand understand in this. This call was veryhelpful to hear some of our current understanding and the many gaps in ourknowledge. (b) (5)NIH-002322(b)(5)I hope that is a reasonable approach, please send any thoughts orsuggestions.(b) (5)Once again, thank you for making time over a weekend and for such aninformed discussion on a complex issue.Thank you and best wishes JeremyFrom: Jeremy Farrar (b)(6)Date: Saturday, 1 February 2020 at 15:34 -------~ = To: "Fauci, Anthony (NIH/NIA ID} [E]" (b)(6)>, PatrickVallance (b)(6)Cc: "Drosten, Christ ian" (b)( >, MarionKoopmans (b)(6)II (b) (6) EdwardrH olmes _...=..=. ==================..=.. .. (b)(6) (~b)~<~6.~)-------------(b)( ~ "Kristian G. Andersen " =========-=-=~ ----------~=(b)( ~, Paul Schreier( (b)( ~(bH ~> , Michael FMedSci ===========-~~--- (b )( ~Subject: Teleconference1st February (2nd Feb for Eddie)Information and discussion is shared in total confidence and not to beshared until agreement on next steps.Dial in details attached.Please mute phones.I will be on email throughout - email Paul or I Paul if any problemsIf you cannot make it, I will phone you afterwards to update .One HourNIH-0023236am Sydney8pmCET7pm GMT2pm EST11am PST(Hope I have the times right!)Thank you for the series of calls and for agreeing to join this call.Agenda• Introduction, focus and desired outcomes - JF• Summary - KA• Comments - EH• Q&A-AII• Summary and next steps - JFKristian AndersonBob Garry- I have not been able to contact Bob. Please forward if you can.Christian DrostenTony FauciMike FergusonRon FouchierEddie HolmesMarion KoopmansStefan PohlmannAndrew RambautPaul SchreierPatrick VallanceAn drew RambautInstitute for Evo lutionary Biolog yAshworth Laboratorie s, University of Edinburgh , Edinburgh , EH9 3FL , UKconta c t - _____ ....,~_.(.,.,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._),.,.,§)The University of Edinburg h is a charitable body, registered in Scotland, with registration numberSC005336.NIH-002324From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 15:45:28 +0000To:Subject:Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E]RE: Thank you so muchMy pleasure!From: Goldner, Shannah (NBCUniversal) <shannah .goldner@nbcuni.com>Se nt: Sunday, February 2, 2020 10:33 AMTo: Conrad, Patricia (NIH/NIA ID) [E)------- -(=bc)-(-=6) Fauci, Anthony {NIH/NIA ID) [El(b)(6)Subject: Thank you so muchDr. Fauci, thank you so much for making time for our show th is morning. We are very grateful to haveyou on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks .Sincerely - and have a good day, though I know a busy one . ShannahAnd Patric ia, thank you so much for your help and patience with me, I appreciate it.ShannahFrom: Conrad, Patricia (NIH/NIAID) [El (b)(6)>Se nt: Saturday, February 01, 2020 8:42 PMTo: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcuni. com>; Fauci, Anthony (NIH/NIAID ) [El(b)(6)Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) <Cynthia.Antoniak@MSNBC.COM>Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interviewAdding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ETlive hit as per below.If there are any changes or cancellations in the morning please call his cell at -----(b)(6) , My cell is (b)(6)Thank you.Sent from my iPhoneOn Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal)<sha n na h.goldner@n bcuni .com> wrote:NIH-002328Patricia, hi. .. the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. Thenumber at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himselfand he can park at the bureau.The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am forpowder and to be seated, that would be appreciated .The producer in NY who will email you the information details for the segment tomorrowis Cyndi Antoniak . If you need to reach her before she reaches you in the morning , heremail is Cynthia.antoniak@nbcuni.com and her phone number is (b)(6)The interview is one on one with our anchors Kendis Gibson and Cori Coffin .If you need more information, please let me know . Thank you for your help and yourpat ience today, I appreciate it.All the best,ShannahShannah GoldnerMSNBCW: 212-664-1289C: (b) (6)From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Sent: Saturday, February 01, 2020 7:54 PMTo: Goldner , Shannah (NBCUniversal) <shannah.goldner@nbcun i.com>Subject : [EXTERNAL] RE: Thank you so muchHi - are we firm for tomorrow? need onsite contact info .. thxFrom: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcun i.com>Se nt: Saturday, February 1, 2020 1:28 PM --------..-;:= To: Conrad, Patricia (NIH/NIAID) [ElCc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~H~ Stover, Kathy {NIH/NIAID)[El CbH6)>Subject: RE: Thank you so muchI will forward all that soon. Thank you!From: Conrad, Patricia (NIH/NIAID) [E] CbH ,>Sent: Saturday, February 01, 2020 1:26 PMTo: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcun i.com>Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID)[E] (b) (6)Subject : [EXTERNAL] RE: Thank you so muchNIH-002329Yes - he can do that hit time - just let us know when it is firm. He willdrive his car to the studio .I will need an onsite name and cell number for him at the studio hereindeFrom: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcun i.com>Sent: Saturday, February 1, 2020 1:20 PMTo: Conrad, Patricia (NIH/N IAID) (E]-------- (..b.)" "('=6)Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy {NIH/NIA ID)[E] (b) (6)Subject: Thank you so muchImport ance: HighPatricia, hi, thank you so much for getting back to me and again, apologies to Dr. Fauci, I dounderstand how swamped he.With that said, I'll confirm the exact time at around 2pm our time, but I think the interviewwill be at approx 7:30am.Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci tobe at the studio by 7:10am-ish?Thank you so much. ShannahFrom: Conrad, Patricia (NIH/N IAID) [E]- -------- (b)(6) Sent: Saturday, February 01, 2020 12:41 PMTo: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcun i.com>Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID)[E) (b)(6)Subject : [EXTERNAL] FW: request for a live interview tomorrow morning, on MSNBCImportance : HighGood afternoon -I believe we can make this work - if we can - it would need to be donein your NBC Studio in WDC at 4001 Nebraska Ave NWWill that work and what would the exact hit time be?NIH-002330From: Goldner, Shannah (NBCUniversal) <shannah.goldner@nbcuni. com>Sent: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6)Subject: request for a live interview tomorrow morning, on MSNBCImport ance: HighDr. Fauci, good morning.Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, todiscuss the latest news about the Coronavirus? The interview would be one on one andapprox 5mins. I saw you on the Today show yesterday and I would love to get you onMSNBC to discuss this, I know our viewers will have a better understanding of the situationif you can take us through itI can arrange a satellite location/transportation/whatever is needed to make this work out.Thank you for your consideration and I hope to hear from you soon.All the best,ShannahShannah GoldnerMSNBCW: 212-664-1289C: ----(b)-(6)NIH-002331From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 15:44:24 +0000To: Daley, George Q.Cc: Collins, Francis {NIH/OD) [El ------ (b)(6));Marston, Hilary {NIH/NIAID) [El;Graham, Barney (NIH/VRC) [ElSubject: RE: Inquiry and possible pone callGeorge:Thanks for the note . There is a lot of communications between scientists in China and theircolleagues in the USA, many with whom they have been collaborating prior to the outbreak.There is no real "coordination" of this response since we do not know who is doing what untilwe are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO isorganizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. Iam sure tha t Chinese scientists will be there. It might be helpful to contact her. Her e-mailaddress is (b)( .I hope that this is helpful. I wi ll follow-up with a call.Best,TonyFrom: Daley, George Q. (b) (6)> ------------- Se nt: Sunday, February 2, 2020 10:32 AM -----~~ To: Fauci, Anthony {NIH/NIAID) [El --------- (b)( ; Fauci, Anthony {NIH/N IAID) (El (b) ( >Subject: Inquiry and possible pone callDear Tony ,Alan Garber , Harvard 's Provost , and I met yesterday with a teamled by Jack Xia, the CEO of China's Evergrande Company , andDr Jack Liu, Evergrande 's chief health officer, who stated thywere acting on behalf of Dr Zhong Nanshan , China's ke pointperson on the coronavirus outbreak see below . CbH4>--------------------------- , andthey arranged a conference call for tomorrow morning EST withDr. Zhong.While I have been mobilizing efforts of our community to react tothe virus and to this request, I am not na"i"ve to the challengingpolitics of such a relat ionship. I do not want to complicate orduplicate efforts already underway, and am writing to requestNIH-002332whatever information you are willing to share on your currentefforts to coordinate a response.If a phone call is more facile, please do not hesitate to try my cell:------ (b)(a6n) ytime today.Sincerely,GeorgeGeorge Q. Daley, MD, PhDDean, Harvard Medical SchoolCaroline Shields Walker Professor of MedicineProfessor of Biological Chemistry and Molecular PharmacologyOffice of the Dean, Gordon Hall25 Shattuck Street, Boston MA 02115Contact: Cb(>6 )(b)(6)From: Jack Liu Cb() 6)Date: Saturday, February 1, 2020 at 11:26 PMTo: Public HMS Email CbH6)Cc: i~fflf!'f (b)(6M)~, ~ Min Chen(b)(6)Subject: Follow up on today's meetingDear Dr. Daley:Per our discussion this afternoon in the conference room at your school, --------NIH-002333(b) (4)Jack Liu, MDNIH-002334From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sun, 2 Feb 2020 15:33:34 +0000To: Collins, Francis (NIH/OD) [ElCc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia(NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [ElSubject: RE: 2019 novel Coronavirus Global research and innovation forum: towards aresearch roadmap Feb 11-12, 2020 Geneva WHO HQFrancis:This is a meeting aimed at setting research priorities and I do not believe that it impacts oroverlaps with the Tedro s proposal. I will have my staff submit some names (mostly high levelprogram people) to represent us at this meeting.TonyFrom: Collins, Francis (NIH/OD) [E] -------- (b)(6) Sent: Sunday, February 2, 2020 10:11 AMTo: Fauci, Anthony (NIH/NIAID) [El------ (=b)c(-=c>Cc: Tabak, Lawrence (NIH/OD) [E] --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) (b )( 6)Subject : FW: 2019 novel Coronavirus Global research and innovation forum : towards a researchroadmap Feb 11-12, 2020 Geneva WHO HQHi Tony ,Just encounte red this message from Soumya of WHO, inviting attendance at a meeting inGeneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal.Who would be the right persons from NIH to propose for Soumya's meeting?FrancisFrom: SWAMINATHAN, Soumya ________ CbC)_ >Sent: Friday, January 31, 2020 4:41 AM------- (b)(6) Collins, Francis {NIH/OD) [E] (b)(6) Cc: SATHIYAMOORTHYV, aseeharan (b)(6)>; RIVEROSB ALTA,A lina Ximena(b)(6)(b)(6); BORGESA, ndrea (b)(6); MCLELLAN, Faith (b)(6)>; HILL,Suzanne Rose (b)(6); GARAPO, Charity Helen (b)(6)>NIH-002335Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmapFeb 11-12, 2020 Geneva WHO HQDear All,I am delighted to inform you that WHO is organizing a global research partners forum on February 11thand 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expectedoutcome is a research roadmap with clearly defined priorit ies and a governance framework to take eachthematic area forward . Several thematic areas will be considered at the meeting, namely: virus,diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science;animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting willbe critical in consensus building on the most important research questions, as well as in building globalpartnerships and collaborations to take this work forward.This meeting is being organized in partnership with GLOPID Rand is being supported by the Bill andMelinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat withinWHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself.As the head of an agency that would play an impor tant role in addressing this new viral outbreak, eitherby undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. Iapologize for the short notice, but you will understand that we have had to plan this in the past fewdays, keeping in mind the evolving situation.Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us.Please copy (bH and (b)(6) in your response.With best wishes,SoumyaChief ScientistNIH-002336From:Sent:To:Fauci, Anthony (NIH/NIAID) [ElSun, 2 Feb 2020 12:35:48 +0000Lorsch, Jon (NIH/NIGMS) [ElSubject : RE: Update from MingExhausted, but OK. Thanks.-----Original Message-----From : Lorsch, Jon (NIH/NIGMS) [E]Sent: Sunday, February 2, 2020 7:35 AM(b)(6)To: Fauci, Anthony (NIH/NIAID) [E] .-..-_- -_-_-_~_ = C>b<.. ..Subject: Re: Update from MingJ hope you are hanging in there!JonOn 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ CbH_6)> wrote:Jon:Best,Tony-----Original Message-----From: Lorsch, Jon (NlH/NIGMS) [E] (b)( ...._.,. _____Sent: Friday, January 31, 2020 6:57 AMTo: Fauci, Anthony (NIH/NlAID) [E].__ ____ Cb _H_6lSubject: FW: Update from MingTony,JonOn 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- CbH > wrote:(b)(6)(b)(6)(b)(6)Thanks~J~o=n. .-_-----------------------------~~ (b)(6)MingSent from my iPadNIH-002337> On Jan 31, 2020, at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > wrote: >> Thanks, Ming. (b)(6) - --------------->> On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS) [E]" ______ C_b)_(6_)> wrote:>> Jon ,>> Here is an uodate of mv situation:>> Best.> Ming>NIH-002338(b)(6)From:Sent :To:(NIH/OD) [ElSubject:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 11:26:13 +0000Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, CarrieRE: More on evolution of coronavirusThe Indian paper is really out landish. Agree about Jon Cohen's nice summary.From: Collins, Francis (NIH/OD) [E] (b)(6)Se nt: Sunday, February 2, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6); Tabak, Lawrence (NIH/OD) [El---------(b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirusIn case you haven't seen, attached is the Indian paper claiming HIV sequences have been inserted into2019-nCoV, which has been roundly debunked.I found Jon Cohen's piece in Science to be a pretty useful summary :https://www .sciencemag.org/news/2020/01/mining -coronavirus -genomes-clues-outb reak-s-originsFCNIH-002339From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 04:24:27 +0000Cassetti, Cristina (NIH/NIAID) [E]Subject:Attachment s:Please handle.From: Ryan Muldoon ------------- (b)(6) Se nt: Thursday, January 30, 2020 3:33 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Subject : ------------ (b)(4)Dear Tony,Kind regards,RyanPrEPB1opharrnRyan MuldoonCEOTel: (b)(6) --=======L----- ~= Email (b) (6) ------------ www .prepbiop harm.comNIH-002340(b)(4l(b) (4)From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 04:2 1:44 +0000Billet, Courtney (NIH/NIAID) [E]Subject: FW: Dear Prof. Anthony Fauci, here is a request from MIT TechnologyReview ( Chinese)NIAID inquiries, please.From: Tao Sun Cb()6 )Sent: Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]- _-_-_-- -~~ CbC>_6>)Subject : Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese)Dear Prof. Anthony Fauci,Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few newquestions to ask. Chinese readers want to know the opinions of foreign independent experts1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need notpanic. What do you think of this view? In reality, Chinese residents are al ready scared and are alreadyrushing to buy masks.2 RO is a developing number, and it is not easy to calculate. Does it make sense to talk about RO at thisstage?3 You had talked about asymptomatic patients, and how public health workers should treatasymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to helpprevent epidemics?4 To what extent will the closure of Wuhan prevent the epidemic?Looking forward to your reply .BestTao Sun- ------- CbH6)>- =f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii :Dear Prof. Anthony Fauci,I am Tao Sun, a repor ter from Beijing. I am currently writing reports for the MIT TechnologyReview (Chinese) .JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and XinhuaNews Agency reported this article . Here are some questions I would like to ask you .1 Some peop le think that it is not necessary to develop a new vaccine against SARS or coronavirus inNIH-002341Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers,and secondly, such outbreaks may not return after the extinction.What do you think of these views?2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after threemonths, so is it still necessary to develop a vaccine?3 You can talk about SARS. How much does a vaccine against SARS actually play?Looking forward to your reply .TAO SUNDEEPTECH MIT Tech nology Review(b)(6)suntao@mittrchina.com7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaag District, Beijinghtt p ://www. m it tr ch i na . comTAO SUNDEEPTECH MIT Technology Review(b)(6)suntao@mittrc hina .com7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijinght tp :// www.m itt rchina.comNIH-002342From :Sent :To:Subject :Please handle.Fauci, Anthony (NIH/NIAID) [ElSun, 2 Feb 2020 04:08:48 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: Strategy to attack 2019-nCoV coronavirusFrom: Jingyue Ju (b)(6)Sent: Friday, January 31, 2020 12:39 PM ----------------- -,;-;-= To : Fauci, Anthony (NIH/NIAID) [E] (b)(6); Redfield,·_ _:_ _ ____;~.:,------------------- Robert R. (CDC/OD) (b)(6)Cc: Mary C Boyce (bH ; Lee Goldman ---------- (b)(6)>; Shelanski, Michael L.- ---------- (b)(6) Subject : Strategy to attack 2019-nCoV coronavirusDear Drs. Fauci and Redfield,Please let me know if you would like to receive the full manuscript.Thank you very much for your consideration .Sincerely,JingyueJingyue Ju, Ph.D.Samuel Ruben-Peter G. Viele Professor of EngineeringProfessor of Chemical Engineering and PharmacologyDirector, Center for Genome Technology & Biomolecular EngineeringColumbia UniversityNorthwest Corner Building, Room lOOOMlNIH-002343(b) (4)Phone: (b)(6)(0ffice) (b)(6) (Cell) ____ _,Fax: 212-851-9330Email: (b)(6)NIH-002344From:Sent :To:Subject:Arnold:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 04:08:13 +0000Arnold MantoRE: Coronavirus issuesThanks for the note. I actually have recommended to several press people that they contactyou when they ask for non-government experts. I will continue to do that.Best,TonyFrom: Arnold Manto (b) ( >Sent : Friday, January 31, 2020 1:03 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] -------- (b)( > Subject : Coronavirus issuesHi, Tony:As this progresses, and as other news items quiet, I am concerned that this is not being handled like the2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t rickywhen public health interventions are the way SARS was handled and remain the focus. I am beingcontacted by the media currently, not because I was in Beijing at the end of SAR$ but because of generalepidemiology credent ials I am t rying to put things into context based on past histo ry, even though Iknow other sensational information may come to light which will further muddy the waters. And weknow who will be the main muddiersKeiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was notbound by clearances etc I am trying to figure out if I can play that role here I have not yet beencontacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to(b) (4)I am attaching a paper which I wrote post 2009 which shows how the way it was handled adverselyaffected programs in much of Europe It might be of interest to those who were not around at thattime .RegardsArnoldArnold S. Manto, M.D.Thomas Francis Collegiate ProfessorDepartment of EpidemiologySchool of Public HealthUniversity of Mich igan1415 Washington HeightsAnn Arbor, Ml 48109-2029Tel: (b)(6)Fax: (734) 764-3192(b)(6)NIH-002345From:Sent:To:Fauci, Anthony (NIH/NIAID) [E)Sun, 2 Feb 2020 04:01:50 +0000toygar civelekSubject : RE: CoronavirusMany thanks!From: toygar civelek ---------- (b) (6) > Se nt: Friday, January 31, 2020 2:09 PM ------- ~= To: Fauci, Anthony {NIH/NIAID) [E]- -------- (b)(6) Subject: CoronavirusDear Mr. Fauci,I am hoping that this email reaches you as I saw this email address on line on the NIHwebsite.As we as the public get to hear, read and see with the current coronavirus scare, here inthe US and worldwide, it is comforting to have professionals and experts like you, whoreally know what they are talking about , what is going on, what can be done, timelines,action plans, and inform the public in a reliable and comforting way, yet being verytransparent, informing the public on social media.Kudos to you sir and please keep up the excellent work.Sincerely,Mur. CivelekNIH-002349From: Fauci, Anthony (NIH/NIAID) [E)Sent : Sun, 2 Feb 2020 04:01:28 +0000To: Conrad, Patricia (NIH/NIAID) [E)Cc: Greg Folkers (b)( ·Barasch, Kimberly (NIH/NIAID) [C];GregFolkers-------- ~(b~)(=6)Subject : FW: Business Council - Invitation to speak at the February 20-21, 2020 meetingat the Ritz Carlton (22nd and M St. NW), Washington, D.C.Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BC Active Members Jan. 2020.pdfI defin itely want o do this. Please respond. Thanks.From: Marlene Colucci <mcolucci@businesscouncil.com>Sent: Friday, January 31, 2020 2:00 PM ------- ~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein<David.Rubenstein@carlyle .com>; MaryPat Decker <marypat.decker@carlyle .com>Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton(22nd and M St. NW), Washington, D.C.Dear Dr. Fauci,On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of TheCarlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in ourmeeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade."(See formal inv itation attached as well as list of CEO members).We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr.Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade.We want to give our CEOs insights into what the next 10 years will bring in terms of detect ion, diagnosisand treatment of diseases. All conversations are strictly off the record and closed press. We will coverall lodging and transportation.As you know, The Business Council is comprised of the chief executive officers of the largest globalcorporations, representing all segments of the economy. We expect at least 150 CEO members, spousesand speakers to be in attendance.As a participant you and your spouse are also invited to join us for our special reception, dinner andspeaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunityfor you to meet our CEO members and spouses, speakers and other special guests in an informalatmosphere.If you are interested and available, please let me know. We can also set up a very brief call with you todiscuss any additional details and answer any questions you may have. We look forward to hearingfrom you and would be honored to have you participate with us again.Warmest regards,NIH-002350MarleneMarlene ColucciEXECUTIVEDIRECTOR'I BUSINESS~ COL NCILT: 202-298 -7650C: (b)(6)F: 202-785-0296NIH-002351From:Sent:To:Fauci, Anthony (NIH/NIAIO) [E)Sun, 2 Feb 2020 03:48:52 +0000Morens, David (NIH/NIAID) [E]Subject: RE: Potential PHS Officer DeploymentGot it.From:M orens, David (NIH/NIAID) [E] ---------- (b)(6) Sent: Friday, January 31, 2020 4:54 PMTo: Fauci, Anthony (NIH/NIAID) [E] -------= (b-)c(-c6-)=; Auchincloss, Hugh (NIH/N IAID) [ E](b) (6) >Subject: Potential PHS Officer DeploymentTony & Hugh, in follow up, the PHS has informed all PHS officers that as of 2/3they are subject to deployment for coronavirus work "without supervisoryapproval", meaning that if needed, officers can be deployed and assignedanywhere, for indefinite periods, by the Assistant Secretary of Health.We are hearing that many officers, especially physicians and nurses, may bedeployed for quarantine efforts and to assist State agencies.I haven't heard anything personally, but just want to let you know. Thesedeployment orders can come with almost no advance warning, although I don'texpect that.David M. Morens, M.D.CAPT, United States Public Health ServiceSenior Advisor to the DirectorOffice of the DirectorNational Institute of Allergy and Infectious DiseasesNational Institutes of HealthBuilding 31, Room 7 A-0331 Center Drive, MSC 2520Bethesda , MD 20892 -2520a (b)(6) (assistants : Kimberly Barasch; Whitney Robinson)[l§] 301 496 4409Q (b)(6)Disclaimer: This message is intended for the exclusive use of the recipient(s) named above. It may contain information that is PROTECTED,PRIVILEGEDa, nd/or CONFIDENTIALa,n d it should not be disseminated, distributed, or copied to persons not authorized to receive suchNIH-002354NIH-002355information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, anydissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the messageand its attachments and notify us immediately.From:Sent:To:Subject :Please handle.Fauci, Anthony (NIH/NIAID) [ElSun, 2 Feb 2020 03:28:01 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: Control 2019-nCoV WuhanFrom: (b)(6)Sent : Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] -----------~-~-- (b)(6)> Subje ct: Control 2019-nCoV WuhanTri-Prime Gene Pharmaceutical CoBeijing ChinaCheng YongQingCEO Tri-Prime Gene.regardsMy name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in1999 in shrimp farms in Ecuador there was a lethal disease among shrimp called the white spot virussyndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China itappeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family thatinfects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog icalmolecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimpfarms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. Theseglycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules inventedin (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepatopancreas. Cytokinins cause thedesquamation of epithelial cells from tubules that end up collapsing to the liver and shrimp pancreas.These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in theshrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp,now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019-nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhancoronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler inanimals that cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted evenwithout symptoms and its incubation is 2 to 14 days.We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan.1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in bananaplantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibitviruses. And we can give them more than 100 million liters to take for more than 100 million liters forhumans to more than 100 million inhabitants of the entire province of Hubei in China, so that they donot transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviraland antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs andimmune boosting immune response in immunocompromised people who have diabetes and high bloodpressure. Others may have cytokinin and immunoglobulin problems . We can finish with the 2019-nCoVWuhan in the environment and in humans so be found in the lungs whose epithelial cells are alreadycollapsing with an increase in inflammation and difficulty breathing . We can beat the coronav irusesNIH-002366thro ughout China.At teRobert VeraGraduated from the (b)(6) ----.!:=======~~---------- What asp p (b) (6) a. 1919 -----------s- -~ -;,:.;,, 4¾ e 1< J·,6(D abc.esABC SOCIEOAOn ~CHI NLos farm acos que pu edencomb atir el coronavirus chino<• Clcnt1lu :o<i dC'I lm,lll uto lk S,1lud de Lsl.id<l'il nidoi; p,·or,<ml'n reutitiz:.lranth irate,di,ei1 :uJo, contra L'Is :\r is Jl,1r a ncc1L•1.1 1· l:lIIL'~ad.1d L' l~1tamicnto-. . Un., fllll'\ ,1\ :,1cunapodrta <.'star lisla en solo lrt?, mcs<.'s, dict>nN. R. C.I.a. C,t?I A..t.ua ado 27/01/2020 10;0'1,Enviado desde mi smartphone Samsung Galaxy.NIH-002367From:Sent :To:Subject :Thanks, Jason.Best regards,TonyFauci, Anthony (NIH/NIAID) [E)Sat, 1 Feb 2020 23:56:07 +0000Jason GaleRE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of SpreadFrom: Jason Gale (BLOOMBERG/ NEWSROOM:) <j.gale@bloomberg.net>Sent : Saturday, February 1, 2020 6:20 PMTo: Fauci, Anthony (NIH/NIAID) [E)_ _____ ..(,b,")"("=6)Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of SpreadHello Dr Fauci ,Just been watching the press conference on You Tube with you and your federal colleagues.Thought you might find this in teresting, if you have time to breat he let alone read media reports!All the best and hope to see you at the end of next month .JasonCoronavirus Lurking in Feces May Reveal Hidden Risk of Spread2020-02 -01 06:55 :00.469 GMTBy Jason Gale(Bloomberg) -- While doctors have focused on respiratorysamples from pneumonia cases to identify coronavirus patients,they might have ignored a less apparent and hidden source of thespread: diarrhea .The novel coronavirus was detected in the loose stool ofthe first U.S. case -- a finding that hasn't featured among casereports from Wuhan, China, the epicenter of the outbreak.However, that doesn't surprise scientists who have studiedcoronaviruses , nor doctors familiar wit h the bug that causedSARS.Diarrhea occurred in about 10-20% of patients afflictedwith severe acute respiratory syndrome about 17 years ago andwas the source of an explosive SARS outbreak in the Amoy Gardensresidential complex in Hong Kong.SARS and Wuhan viruses bind to the same distinctly shapedprotein receptors in the body that are expressed in the lungsand intestines, making these organs the primary targets for bothviruses, said Fang Li, an associate professor of veterinary andbiomedical sciences at the University of Minnesota.The discovery of the Wuhan virus, dubbed 2019-nCoV, in thefecal material of the 35-year-old man treated at the ProvidenceNIH-002370NIH-002371Regional Medical Center Everett in Washington is "interesting,"said Scott Lindquist, the state epidemiologist for infectiousdisease at Washington's Department of Health."That adds to the knowledge about this,'1 he told reporterson a conference call Friday. "It's not only excreted in yourrespiratory secretions, it's also secreted in your stool."Read More: What You Need to Know About the SpreadingCoronavirusResearchers don't yet know how exactly 2019-nCoV spreadsfrom person to person, but suspect it's most likely from cominginto contact with virus -containing droplets that could beemitted by an infected person's cough and transferred to theirhands or surfaces and objects.Face MasksThat's led to a run on face masks. But those may be oflimited benefit in the event the virus is being transmitted viathe fecal-oral route, said John Nicholls, a clinical professorof pathology at the University of Hong Kong.Squat latrines, common in China, lacking covers and handsthat aren't washed thoroughly with soap and water after visitingthe bathroom could be a source of virus t ransmission, saidNicholls, who was part of the research team that isolated andcharacterized the SARS virus.A virus-laden aerosol plume emanating from a SARS patientwith diarrhea was implicated in possibly hundreds of cases atHong Kong's Amoy Gardens housing complex in 2003. That led thecity's researchers to understand the importance of the virus'sspread through the gastrointestinal tract, and to recognize boththe limitation of face masks and importance of cleanliness andhygiene, Nicholls said in an interview."I think in Wuhan, that would be a very likely place whereyou might get the transmission" from fecal material , he said."If it's using the same receptor as for SARS, I can't see why itshouldn't be replicating in the gut."Nicholls and colleagues at the University of Hong Kong aretesting laboratory models of human tissues and specimens tounderstand where and how the Wuhan virus replicates, he said.Emerging EvidenceDoctors have reported diarrhea infrequently in 2019-nCoVpatientsadmitted to Wuhan hospitals, though it's been moreprominent among reported cases outside the city, includingmembers of a Shenzhen family infected in Wuhan, and morerecently in the first U.S. case in Washington state . Thatpatient exper ienced a two -day bout of diarrhea from which aNIH-002372sample tested positive.The lab in Washington didn't attempt to grow the virus fromthat specimen, said Lindquist, the state epidemiologist,"because it wasn't going to add anything to his care."Many of the emerging coronaviruses are so-calledpneumoenteric viruses, meaning they can replicate both in therespiratory tract and the gastrointestinal system, said RalphBarie, professor of microbiology and immunology at the GillingsSchool of Global Public Health at the University of NorthCarolina at Chapel Hill, who has studied coronaviruses fordecades.Overwhelmed by hundreds of severely sick pneumoniapatients, doctors in Wuhan might not have focused on any gastricsigns, Barie said in a phone interview.'So Overwhelmed'"The Chinese are so overwhelmed at the moment and trying todo a combination of treating patients and dealing with the scopeof the outbreak, and then trying to get out papers that describewhat's happening," he said.Any virus in stool is more likely to be present during theacute phase of an infection, occuring before hospitalizedpatients develop a life -threatening complication known as acuterespiratory distress syndrome, Barie said."I have also spent most of my time focusing on therespiratory tract symptomology rather than the gut because ofthe relationship between these different emerging viruses andacute respiratory distress syndrome," he said.Zijian Feng, deputy director general of Chinese Center forDisease Control and Prevention, and colleagues released a reportWednesday on the first 425 Wuhan cases, and noted that earlyinfections that didn't appear to display typical signs -- suchas fever and viral pneumonia -- or had mild symptoms might havebeen missed."The initial focus of case detection was on patients withpneumonia, but we now understand that some patients can presentwith gastrointestinal symptoms," Feng and co-authors said intheir report, which was published in the New England Journal ofMedicine.Emerging evidence of virus-containing diarrhea warrantsfurther investigation, said Peter Collignon, a professor ofclinical medicine at the Australian Nationa l University MedicalSchool in Canberra, who advises the Australian government oninfection control."This is something new," Collignon said in an interview."We presume it's respiratory droplets, but with SARS there wasevidence of other routes . We have to keep an open mind."NIH-002373To contact the reporter on this story:Jason Gale in Melbourne at j.gale@bloomberg.netTo contact the editors responsible for this story:Brian Bremner at bbremner@bloomberg.net ;Shamim Adam at sadam2@bloomberg.netFrom:Sent:To:Subject:Please handle.Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 23:19:46 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: article from IIT/lndia on CoronovirusFrom: Hong Cai (b)(6)Sent: Saturday, February 1, 2020 5:33 PMTo: WRB Gmail <wrbrody@gmail.com>; Fauci, Anthony (NIH/NIAID) [E]Subject: Re: article from Ill /India on CoronovirusDear Fauci,(b) (4)-------- (b) (6) >I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 JThank you for your assistance in advance!-me~s, abiotec h"" ( -Hong Cai, Ph.DCo-Founder and CEOMesa Biotech, Inc.6190 Cornerstone Court East, Suite 220San Diego, CA 92121www.mesabiotech.com(b)(6)(b)(6)From: WRB (b)(6) ----------- Date : Saturday, February 1, 2020 at 7:27 AMNIH-002374(b) (4)To: "Anthony (NIH/NIAID) Fauci [E]" (b)(6)Cc: Hong Cai (b)(6)Subject: article from IIT/lndia on CoronovirusHi Tony,I hope you are coping with the chaos around coronavirus.No doubt you have seen, but in case not, I am sending a copy.Hopefully someone at NIH is try ing to replicate this study or to find problems with the irmethodology.With best wishes,BillWilliam R. Brody(b)(6~Johns Hopkins University-------- Salk Institute for Biological StudiesNIH-002375(b) (4)From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 22:06:26 +0000To:Subject:Jeremy Farrar;Collins, Francis (NIH/OD) [ElRE: TeleconferenceThanks, Jeremy. We really appreciate what you are doing here. Pleasure to work with you.Best,TonyFrom: Jeremy Farrar ________ Cb_H_6)>Se nt: Saturday, February 1, 2020 4:00 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)>Cc: Fauci, Anthony (NIH/NIAID) [El- ------- (b)(6) Subject: Re: TeleconferenceWe are altogether as you know! Conversations with you and Tony, and Patrick and others - alwaysgreat working with you bothFrom: Francis Collins (b)(6)>Date: Saturday, 1 February 2020 at 20:50To: Jeremy Farrar (b)(6)Cc: "Fauci, Anthony (NIH/N IAID) [E]" ---------- (b)( Subject: Re: TeleconferenceHi Jeremy,I can make myself available at any time 24/7 for the call with Tedros. Just let me know.Thanks for your leadership on this critical and sensitive issue.FrancisSent from my iPhoneOn Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ CbH_ > wrote:I have rejoined so a line is open if any help to rejo in.From: Jeremy Farrar ---------- (b)(6)>Date: Saturday, 1 February 2020 at 19:56To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ C~>b~<, Francis CollinsCbH >, Michael FMedSci CbH6), PatrickVallance (b)(6) ------------- Subject : Re: TeleconferenceNIH-002376Can I suggest we shut down the call and then redial in?Just for 5-l0m ins?From: Mar ion Koopmans ------------ (b)(6)Date: Saturday, 1 February 2020 at 19:43To: Jeremy Farrar CbH6J>Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._ ____________ Cb _H_6)>, Patrick VallanceCb)(~ "Drosten, Christian"(b)(~(b)({;j1>, Edward Holmes ! (b) (~,CbH6)>",K ristian G. Andersen" ! CbH~,P aul"S"-:c':h_r_e"i.e"-"r=1====-..;__----------====~ C"Hb="6'=):':]------======-C-~b)~(~ M ichael FMedSci f- -------------- Cb)~( Francis Collins I CbH~>Subject: Re: TeleconferenceOn 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote:Kristen and Eddie have shared this and will ta lk through it on the call. Thankyou.Hope it will help frame the discussions.From: Jeremy Farrar CbH6J>Date: Saturday, 1 February 2020 at 15:34NIH-002377(b) (5)NIH-0023781st February (2nd Feb for Eddie)Information and discussion is shared in total confidence and not to beshared until agreement on next steps.Dial in detail s attached.Please mute phones.I will be on email throughout - email Paul or I Paul if any problem sIf you cannot make it, I will phone you afterwards to update .One Hour6am Sydney8pm CET7pm GMT2pm EST11am PST{Hope I have the times right!)Thank you for the series of calls and for agreeing to join this call.Agenda• Introduction, focus and desired outcomes - JF• Summary - KA• Comments - EH• Q&A-AII• Summary and next steps - JFKristian AndersonBob Garry - I have not been able to contact Bob. Please forward if you can.Christian DrostenTony FauciMike FergusonRon FouchierEddie HolmesMarion KoopmansStefan PohlmannAndrew RambautNIH-002379Paul SchreierPatrick Vallance<Coronavirus sequence comparison[l] .pdf>From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sat, 1 Feb 2020 22:00:47 +0000To : Marston, Hilary (NIH/NIAID) [E]Cc: Conrad, Patricia (NIH/NIAID) [E]Subject: FW: FOR YOUR REVIEW: Staff Communication on Novel CoronavirusAttachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx,Draft_ OH R_Flexibilities_Novel_ Coronavirus_2 .1.2020.docxPlease handle this. ThanksFrom: Myles, Renate (NIH/OD) [E] -------- (b) ( ·> Se nt: Saturday, February 1, 2020 4:12 PM ------ ..-.-,= To: Fauci, Anthony {NIH/NIAID) [El (b)(6b; Billet, Courtney (NIH/NIAID) [E](b)( >; Stover, Kathy (NIH/NIAID) [El (b)(6h ; Routh, Jennifer(NIH/NIAID) [E) (b)( >Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E]Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie-:--.-:-:-:-:-:7.::====,........_{NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El(b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth"(:N"-"I-H/-0:--:D:--): -:[-E: :)- :;=====:...~ C~)b ~(6)Subject : FOR YOUR REVIEW: Staff Communication on Novel CoronavirusGood afternoon, Dr. Fauci and team:Working in coordinat ion with OHR, ORS, OIR, and others, we have developed two communicationproducts to address questions/concerns that are being raised by NIH staff related to the novelcoronavirus. The two products are:1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities inresponse to coronavirusThese products are provided for your review and guidance. We also plan to share with HHS forreview/awareness. The current plan to disseminate these products on Monday. We look forward to yourinput.Best,RenateRenate Myles, MBADeputy Director for Public AffairsOffice of Communications and Public LiaisonNational Institutes of HealthTel: (b) (6)NIH-002380From:Sent :To:Subject:YesFauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 20:03:12 +0000Jeremy FarrarRE: TeleconferenceFrom: Jeremy Farrar (b)(6)Sent : Saturday, February 1, 2020 2:56 PMTo: Fauci, Anthony (NIH/NIAID) [E]-------= (b")'"c=" >; Collins, Francis (NIH/OD) [E](b)( ·; Ferguson, Mike (b)( ; Patrick Vallance(b)(6)Subject: Re: TeleconferenceCan I suggest we shut down the call and then redial in?Just for 5-lOmins?From: Marion Koopmans ------------ (b)(6)Date: Saturday, 1 February 2020 at 19:43To: Jeremy Farrar ! (b)(~Cc: "Fauci, Anthony (NIH/N IAID) [E]"f (bH ~ , Patrick Vallance ----""."-----:-:-:==:...-------~~ (b)( ~ >, "Drosten, Christian" I (b)(6) i>,(b)( ~ Edward Holmes(b) (~ >,(b)( ~ "Kristian G. Andersen" !Paul Schreier ! (b)( ~ --===========~~-----~======~~- Micha e I FMedScil- ----------- (bH ~ >, FrancisC ollins!- -------- (bH ~ > Subject: Re: TeleconferenceOn 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote :Kristen and Eddie have shared this and will talk through it on the call. Thank you.NIH-002381(b)(5)Hope it will help frame the discussions.From: Jeremy Farrar CbH6J>Date: Saturday, 1 February 2020 at 15:341st February (2nd Feb for Eddie)Information and discussionis shared in total confidencea nd not to be shared untilagreement on next steps.Dial in details attached.Please mute phones.I will be on email throughout - email Paul or I Paul if any problemsIf you cannot make it, I will phone you afterwards to update.One Hour6am Sydney8pm CET7pm GMT2pm EST11am PST(Hope I have the times right !)Thank you for the series of calls and for agreeing to join this call.Agenda• Introduction, focus and desired outcomes - JF• Summary- KA• Comments - EH• Q&A-AII• Summary and next steps - JFKristian AndersonBob Garry - I have not been able to contact Bob. Please forward if you can.Christian DrostenNIH-002382NIH-002383Tony FauciMike FergusonRon FouchierEddie HolmesMarion KoopmansStefan PohlmannAndrew RambautPaul SchreierPatrick Vallance<Coronavirus sequence comparison[l] .pdf>From:Sent :To:Subject:Please handle.From: Albert RizzoFauci, Anthony (NIH/NIAID) [ElSat, 1 Feb 2020 19:02:40 +0000Auchincloss, Hugh (NIH/NIAID) [ElFW: Offering assistance during this public health emergency(b)(6) -------- Sent: Friday, January 31, 2020 5:11 PM ------~~ To: Fauci,A nthony {·_N IH_/;N__ IA ID_:)_ .[.E:..]. !.:::::===-~:--- (b)(6)Cc: Harold Wimmer (b)(Subject: Offering assistance during this public health emergencyHello Dr. Fauci:As the coronavirus continues to be a public health emergency, the American Lung Association isclosely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Associationis working to help relay impo rtan t public health information provided by the various agencies.As Chief Medical Officer for the American Lung Association, and with the full support of ourCEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American LungAssociation support on strategies that wou ld be appropriate for our organization to participatein or communicate.I am happy to discuss any potent ial opportunities in which you feel we may be of assistance .Sincerely,Albert A. Rizzo MD FACP FCCPChief Medical OfficerAmerican Lung AssociationCell (b)(6)NIH-002384From:Sent :To:Subject :Please handle.Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:55:58 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: Consultancy request - CoronavirusFrom: Tatsch, Fernando Franciosi (b)(6)>Sent: Friday, January 31, 2020 6:39 PMTo: Fauci, Anthony (NIH/NIAID) [E] --------=- (b')""('=6)>Cc: Bacher, Hans P (b)(6)>; Vallabh, BhadrishSubject: RE: Consultancy request - CoronavirusDear Dr. Fauci,The below invitation is for a meeting identica l to an advisory board .We wonder if a short phone call could be beneficial to offer further context.With best regards, Fernando TatschFERNANDO TATSCH, MD, MBATherapeutic Area Head - HCV / RSVGlobal Med ical Affairs2SW 102 08 I 1 N Wauk egan Rd I North Chicago, IL 60064OFFICE (b) (6) I CELL (b) (6) I EMAIL-------- (=b)~(=6 )abbvie.com(b) (6) >This commu nic;,ti on may con t;iin info rmation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded recip ient,please note that any oth er dissemination , distrib ution, use or copying of this communication is strictly prohibi ted. Anyone who receives thismessage in erro r should not ify the sender immediately by telephone or by return e-mail and delete it from his or her computer.From: Tatsch, Fernando FranciosiSent : Thursday, January 30, 2020 4:53 PMTo· (b)(6)Subject: Consultancy request - CoronavirusDear Dr. Fauci,On behalf of AbbVie, I would like to explore your interes t and availabi lity for a scientific consultation.AbbVie is interested in your scientific view of the 2019-nCoV epidemic.Your assessment will be very informa t ive for us in the context of --------------- (b)(4)NIH-002385If you are interested, we will need a brief CV in ord er to elaborate a consultation contract .Once the contract is executed, we would like to invite you for a phone conference which will include fewmedical AbbVie colleagues .Looking fo rward to hearing from you .With best regards, Fernando TatschFERNANDO TATSCH, MD, MBATherapeutic Area Head - HCV / RSVGlobal Medical Affairs25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064OFFICE- t (b)(6) I CELLJ (b) (6)11E MAIL_ _______ ('b"~'"c'=abbvie.comThis commu nicati on may contain info rmation that is prop rietary, confident ial, or exempt from disclosure. If you are not the intended recipient,please note that any other dissemination, distr ibut ion, use or copying of this communication is strictly proh ibited. Anyone who receives th ismessage in error should not ify the sender immediate ly by telephone or by return e-mail and delete it from his or her compute r.NIH-002386From:Sent:To:Cc:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:50 :25 +0000Conrad, Patricia (NIH/NIAID) [ElSubject:Billet, Courtney (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [C]FW: 60 Minu tes/ CoronavirusIf we can fit this in next week depending on what is hitt ing the fan, I will do it.From: Conrad, Patricia (NIH/NIAID) [E] ---------(b)(6)>Sent: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El ".-i_-_ -_-__-_~_~ Cb<>.~. ..>Subject: Fwd: 60 Minute s / CoronavirusPis adviseSent from my iPhoneBegin forwarded message:From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Cb _H_j;j>Date : January 31, 2020 at 7 :52:16 PM EST -------..,,.,.., = To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ :(-b:)_:<-,-..>Cc: "Billet, Courtney (NIH/NIAID) [E]" -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) [E)" (b) (6)Subject: Fwd: 60 Minute s/ CoronavirusHi Patty,See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest analternative? Note, this isn't for on-camera - -it's background fo r a potential story .Sent from my iPhoneBegin forwarded message:From: "Lieberm an, Marc E." <MLP@cbsnews.com>Date : January 31, 2020 at 5:57 :24 PM ESTSubject: 60 Minutes / Coronavirus(b)(6)Hi, I am a producer at 60 Minutes researching a possible story about thecoronavirus outbreak. The effort to find a vaccine strikes me as interest ingand I wonder if we might be to chat about it. I am going to be in the DC areanext week. Would you have time for a brief meeting either Wednesdaymorning or Tuesday? Thanks in advance fo r your help .Best,NIH-002387Marc LiebermanMarc Lieberman I Producer I 60 Minutes I w: 212-975-6385 c: -----(b)(6) I mlp@cbsnews.comNIH-002388From:Sent:To:Subject:Fauci, Anthony (NIH/NIAIO) [ElSat, 1 Feb 2020 18:45:22 +0000Folkers, Greg (NIH/NIAID) [E]RE: ASF: Dan Chertow invitationNo prob lem with Dan doing this.From: Folkers, Greg (NIH/NIAID) [E] -------- CbH > Sent: Friday, January 31, 2020 10:05 PMTo: Billet, Courtney (NIH/NIAID) [E]-------=- (b')"("=' Fauci, Anthony (NIH/NIAID) [E](b)(6)>Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/N IAID) [E](b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6) Routh, Jennifer -~---~==:::!......:___....:...~ ~(NIH/NIAID) [E] (b)(6)Subject: RE: ASF: Dan Chertow invi tationAgree with CourtneyDan is a good speaker and would represent nih we llFrom: Billet, Courtney (NIH/NIAID) [El -------- (b)(6)> Sent: Friday, January 31, 2020 9:40 PM ------= = To: Fauci, Anthony (NIH/NIAID) [El CbH6J1>Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [ElCbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~(NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)>Subject: ASF: Dan Chertow invitationDan Chertow has been asked to speak at this event, which has some rather high profile participants andmedia attendance. He would like to do it.■ Do you agree?From: "Cohen, Justin (NIH/CC/OD) [E]" -------- (b)(6)>Date : Friday, January 31, 2020 at 4:43:08 PM ------~= To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]"CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney(NIH/NIAID) [El" (b)(6)-:":"".":"'.-:-:-::-:-:--:-::-:~==---- :;;;-;-,-,=Cc: "Burklow, John (NIH/OD) [El" -------- (b)(6) , "Wojtowicz, Emma (NIH/OD) [El"NIH-002389(b)(6), "NIAID NEWS {NIH/NIAID)" <---------- NIAIDNEWS@niaid.nih.gov> Subject: FW: coronavirus speaking opportunityObvious ly given the current environment (not to ment ion some of the names involved in the event),want to make sure I'm in lockstep with you all from square one . How would you like me to proceed withthe request below? The event is open to the public/ press.From: Chertow, Daniel (NIH/CC/CCMD) (El- ------- (b)(6)> Sent: Thursday, January 30, 2020 6:16 PM ------~= To: Cohen, Justin {NIH/CC/OD) [El- ------- (b)( >; Freimuth, Molly {NIH/CC/OC) [El (bH >Cc: Suffredini, Anthony (NIH/CC/CCMD) [El ______ Cb_H_6)>; Masur, Henry (NIH/CC/CCMD) [El(b)(6)Subject: FW: Hudson Institute speaking requestDear Justin,I am checking back in with you regarding the below invitation to speak.I would like to participate in this if possible.Please confirm that you have received my email.Thank you.Sincerely,DanFrom: "Asha M. George" <asha .geo rge@b iode fensecomm ission .org >Date: Thursday , January 30, 2020 at 6:09 PM ------~~ To: "Chertow, Daniel (NIH/CC/CCMD) [E]" CbH6J>Subject: Re: Hudson Institu te speaking requestDear Dan,Sorry, we have changed something slightly. Instead of taking questions directly from theaudience, we will obtain questions from the audience via email while the first part of theevent occurs, curate them, and then have them available for Senator Lieberman to askthem of the speakers.AshaAsha M. George, DrPHExecutive DirectorNIH-002390BIPARTISAN COMMISSION ON BIODEFENSE202.974.2416biodefensecommission.orgLinkedln I Twitter I Facebook I lnstagramI~ BIPARTISAN~ COMMISSIONON BIODEFENSEBeyondth e blueprintFrom: Asha M. George <asha.geor ge@biodefe nsecommission.org>Sent : Thursday, January 30, 2020 6:02 PMTo: Chertow, Daniel (NIH/CC/CCMD) [E]------ -(-b="H=6)Subject : Re: Hudson Institute speaking requestDear Dan,Here are some more specifics regarding the event we will holding at Hudson Institute onnovel coronavirus. The meeting will be on February 10th, from 2:00 - 3:30 pm in theStern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vaniaAvenue, NW, 4th floor, Washington, DC 20004.We also have the executive conference room reserv ed from 1 :30 pm on. Please plan toarrive around then, so that you can talk with Senator Lieberman and the other speakersbefore the event starts at 2:00 pm. Just ask the receptionist to direct you where to go.Here are the speakers:• Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense• Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, StrategicCommunications, Global Public Policy and Population Health , Merck; formerDirector, Centers for Disease Control and Prevention• Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP,EcoHealth Alliance• The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former DeputyAssistant to President Trump for National Security; former Special Assistant tothe President and Senior Director for Weapons of Mass Destruction andBiodefense• Mr. Eric Brown, Senior Fellow, Hudson InstituteNIH-002391NIH-002392• Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, EmergingPathogens Section , Critical Care Medicine Department , Clinical Center &Laboratory of lmmunoregulation , National Institute of Allergy and InfectiousDiseases , National Institutes of Health (invited)The setting will be relatively informal. Scooter Libby will first introduce SenatorLieberman . Then Senator Lieberman will make a short opening statement, and look toBilly to set the stage and talk about the zoonotic nature of the disease , associateddisease management considerations , etc., in about 5 minutes. The Senator will then askeach of the other speakers to say a few words from their perspectives . After that,Senator Lieberman will ask some questions of the group, allowing you all to answer andconverse. All of this should take about 45 minutes. Then we will allow the audience toask questions .We are planning for Senator Lieberman to moderate the discussion and take questionsfrom the audience , but if for some reason he cannot do so, then Billy Karesh will.I hope you will be able to make it, Dan. Let me know if you have any questions (and ifyou will be able to make it, of course) and I look forward to seeing you on February10th.AshaAsha M. George, DrPHExecutive DirectorBIPARTISAN COMMISSION ON BIODEFENSE202.974.2416biodefensecommission.orgLinkedln I Twitter I Facebook I lnstagramI~ BIPARTISAN~ COMMISSIONON BIODEFENSEBeyondth e blueprintFrom: Chertow, Daniel (NIH/CC/CCMD) [E] ______ C>bC_6>)Sent: Tuesday, January 28, 2020 7:18 PMTo: Asha M. George <asha.george@biodefen secommission.org>Subject : Re: Hudson Institute speaking requestDear Asha,Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in orderto participate.I will reach out to them now and get back to you.Thank you .DanFrom: "Asha M. George" <asha.george@ bio defensecomm ission .o rg>Date: Tuesday , January 28, 2020 at 7:15 PM ------~~ To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( >Subject: Re: Hudson Institute speaking requestDear Dan ,Thank you! The meeting will be held on February 1 oth . We are still trying to nail down atime with Senator Lieberman and Governor Ridge, so I will get back to you about that assoon as possible , hopefully tomorrow.The meeting will be open to the public and to the press, but Hudson Institute is a thinktank , so it's never a negative or rowdy crowd.AshaAsha M. George, DrPHExecutive DirectorBIPARTISAN COMMISSION ON BIODEFENSE202.974.2416biodefensecommission.orgNIH-002393Linkedln I Twitter I Facebook I lnstagrami~ BIPARTISANM. COMMISSIONON BIODEFENSEBeyondth e blueprintFrom: Chertow, Daniel (NIH/CC/CCMD) (E) (b)(6) _______... _Sent : Tuesday, January 28, 2020 5:53 PMTo: Asha M. George <asha.geo rge@b iode fensecommission.org>Subject : Re: Hudson Institute speaking requestDear Asha,I am available Feb 10th or 13th and would be happy to present to the group.Please clarify who will be in attendance and if the event is open or closed to press/public as this wouldrequi re add itional clearance on my end .Thank you.Sincerely,DanDaniel S. Chertow, MD, MPH, FCCM, FIDSACAPT, United States Public Health ServiceHead, Emerging Pathogens SectionCritical Care Medicine Department , NIH Clinical Center &Laboratory of lmmunoregulation, NIAIDFrom: "Asha M . Georg e " <asha .geo rge@b iode fensecomm issio n.o rg>Date: Monday , January 27, 2020 at 6:09 PMNIH-002394To: "Chertow, Daniel (NIH/CC/CCMD) [E]"Subject: Hudson Inst itute speaking requestDear Dr. Chertow,(b)( 6)I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired byformer Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is HudsonInstitute, one of the think tanks here in DC. Hudson lnstitute's chair of the board oftrustees (Sarah May Stern) has asked Hudson Institute to run a 90 minute meeting onthe novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ingtogether in short order .Considering your experience on the ground dealing with other outbreaks , HudsonInstitute invites you to speak at this event. In addition to one of Hudson lnstitute's Chinaexperts , we are also seeing whether Senator Lieberman and Governor Ridge areavailable to speak.Here are the dates they are a looking at: February 6, February 1 O, and February 13.Cou ld you let me know if you are available and if so , when on those dates?Thank you for your consideration, Dan. I look forward to hearing from you soon.AshaAsha M. George, DrPHExecutive DirectorBIPARTISAN COMMISSION ON BIODEFENSE202 .974.2416biodefensecommission .orgLinkedln I Twitter I Facebook I lnsta gramI~ BIPARTISAN~ COMMISSIONON BIODEFENSEBeyondth e blueprintNIH-002395From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:43:31 +0000Kristian G. AndersenSubject: RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's originsThanks, Kristian. Talk soon on the call.From: Kristian G. Andersen (b) (6)1> -------- Sent : Friday, January 31, 2020 10:32 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~------Cc: Jeremy Farrar (b) ( >Subject : Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's originsHi Tony,Thanks for sharing. Yes, I saw th is earlier today and both Eddie and myself are actually quoted in it . It's agreat article, but the problem is that our phylogenetic analyses aren't able to answer whether thesequences are unusual at indivi dual residues, except if they are completely of f. On a phylogenetic t reethe virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir .The unusual features of the virus make up a really small part of the genome (<0.1%) so one has to lookreally closely at all the sequences to see that some of the features (potentially) look engineered.We have a good team lined up to look very critically at this, so we should know much more at the end ofthe weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all findthe genome inconsistent wit h expectations from evolutionary theory . But we have to look at this muchmore closely and th ere are still further analyses to be done, so tho se opinions could still change.Best,KristianOn Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E)- ------- (b)(6)> wrote:Jeremy/Kristian:This just came ou t today. You may have seen it. If not, it is of interest to the cur rentdiscuss ion.Best,TonyFrom: Folkers, Greg (NIH/NIA ID) [E)_ ______ C>bC_6 )Sent: Friday, January 31, 2020 8:43 PMSubje ct : Science: Mining coronavirus genome s for clues to the outbreak 's originsNIH-002396As part of a long-running effort to see what viruses bats harbor, researchers in China collect one froma cave in Guandong.EcoHealth AllianceMining coronavirus genomes for clues to theoutbreak's originsBy Jon CohenJan. 31, 2020, 6:20 PMattaaaggtt tataccttcc caggtaacaa accaaccaac t ttcgatctc ttgtagatct ...That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viralpathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frighteningthe entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virusfrom patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. Theseviral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fitson the family tree of related viruses found in bats and other species. They have also given glimpsesinto what this newly discovered virus physically looks like. how it's changing, and how it might best opped."One of the biggest takeaway messages [from the viral sequences] is that there was a singleintroduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformaticsspecialist at the University of Washington, Seattle. The role of Hua nan Seafood Wholesale Market inWuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined withsampling the market's environment for the presence of the virus, is clarifying that it indeed had animportant early role in amplifying the outbreak. The vira l sequences, most researchers say, also knockdown the idea the pathogen came from a virology institute in Wuhan.In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book toproduce the virus. Although it's one of the many viruses whose genes are in the form of RNA,scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, tomake it easier to study. Many analyses of 2019-nCoV's sequences have already appeared onviro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. Thesharing of the sequences by Chinese researchers allowed public health labs around the wor ld todevelop their own diagnostics for the virus, which now has been found in 18 other countries.(Science's news stories on the outbreak can be found here.)NIH-002397When the first 2019-nCoV sequence became available, researchers placed it on a family tree ofknown coronaviruses-wh ich are abundant and infect many species-and found that it was mostclosely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at theWuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acuterespiratory syndrome (SARS), a disease whose initial outbreak was also in China more than 15 yearsago. But the SARS coronavirus has a similarly close relationship to bat viruses, and sequence datamake a powerful case that it jumped into people from a coronavirus in civets that differed fromhuman SARS viruses by as few as 10 nucleotides. That's one reason why many scientists suspectthere's an "intermediary" host species-or several-between bats and 2019-nCoV.According to Bedford 's analysis, the bat corona virus sequence that Shi Zheng-Li's team highlighted,dubbed RaTG13, differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org, a site he cofounded,Bedford has created coronavirus family trees (example below) that include bat, civet, SARS,and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it'seasy to see the differences and similar ities between the sequences.)~ .--..... .-...1. 1 ,.--·-_.- --~111(4::-1 ,-_u. ,Ill~ .. J~ ----------..-.-.--.-- ----r .._ . .-. . .1..-. . ..~......-. ....-.- --- c::=.~,:::::::•0 00 om '"" '"" fl lJ OJ• Ot •Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between theviruses with the presumed rates of mutation in other coronav iruses. So it likely took decades forRaTG13-like viruses to mutate into 2019-nCoV.Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, similarlyhas a link to bat viruses. But studies have built a compelling case it jumped to humans from camels.And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see.NIH-002398100 TGEVMlnkCoV100 Ferret CoVBat CoV CDPHE15Scotophilus bat CoV 512PEDVBat CoV HKU10Mlnlopterus bat CoV 1100Miniopterus bat CoV HKU8Human CoV NL63Bal NL63-related CoVHuman CoV 229ESADS-CoVRhinolophus bat CoV HKU2Human CoV OC43100 Murine hepatitis virusRat CoV HKU24Human CoV HKU1100 Human MERS-CoVCamel MERS-CoVPfplstra/lus bat CoV HKUSTytonycteris Bat CoV HKU4Hedgehog CoV100 100 SARS-CoV BJ0 1Civet SARS-CoV S23Bat SARSr-CoV WIV1Bat SARSr-CoV SHC014Bat SARSr-CoV L YRa11go Bat SARSr-CoV Rf1Bat SARSr-COV ZC4597 Bat SARSr-CoV HKU3-1Bat SARSr-CoV BM48-31BetaCoV/Wuha n/WIV0S /2019100 BataCo V/Wuha n/WIV02 /2019100 BetaCoV/Wuha n/WIV0-4/2 0198e taCoVrNuha nlWIV06 /2019100 BctaCoV/Wuha n/WIV07 /201997Bat CoV RaTG13Bat Hp BetaCoV Zhejiang 2013Rousettus bat CoV HKU9100 Bat CoV GCCDC1IBV0.1The longer a virus circulates in a human popu lations, the more time it has to develop mutations thatdifferentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to datediffer from each other by seven nucleotides at most, this suggests it jumped into humans veryrecently. But it remains a mystery which animal spread the virus to humans . "There's a very large grayarea between viruses detected in bats and the virus now isolated in humans," says Vincent Munster,a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronavirusesin bats, camels, and others species.Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but whetherit was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoVcases-27 of the fi rst 41 in one repor t, 26 of 47 in another -wer e connected to the Wuhan market,but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jumpinto people happened elsewhe re.NIH-002399According to Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafoodmarket has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoVand all were in the huge market's western portion, which is whe re wildlife were sold. "The positivetests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist atthe University of Sydney who collaborated with the first group to publicly release a 2019-nCoVsequence. "Such a high rate of positive tests would strongly imply that animals in the market played akey role in the emergence of the virus ."Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which,if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it'sreally, really difficult to try and determine what the natural host is," says Kristian Andersen, anevolutionary biologist at Scripps Research.One possible explanation for the confusion about where the virus first entered humans is if there wasa batch of recently infected animals sold at different marketplaces. Or an infected animal trader couldhave transmitted the virus to different people at different markets. Or, Bedford suggests, those earlycases could have been infected by viruses that didn't easily transmit and sputtered out. "It would behugely helpful to have just a sequence or two from the marketplace [environmental sampling] thatcould illuminate how man zoonoses occurred and when they occurred," Bedford says.A research group sent fecal and other bodi ly samples from bats they trapped in caves to the WuhanInstitute of Virology to search for coronaviruses.EcoHealth All ianceIn the absence of clear conclusions about the outbreak's origin, theories thrive, and some have beenscientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by theJournal of Medical Virology received substantial press coverage when it suggested that "snake is themost probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied!!-Conspiracy theories also abound. A CBC News report about the Canadian government deportingChinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted onsocial media to suggest that they were spies who had smuggled out coronaviruses. The WuhanInstitute of Virology, which is the premier lab in China that studies bat and human coronaviruses, hasalso come under fi re. "Experts debunk fringe theory linking China's coronavirus to weaponsresearch," read a headline on a story in The Washington Post that focused on the facility.Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a newblosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University,Piscataway, expressing concerns about accidental infections, which he noted repeatedly happenedNIH-002400with lab workers handling SARS in Beijing. Ebright, who has a long history of raising red flags aboutstudies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications weremade to a SARS-like virus circulating in Chinese bats to see whether it had the potential to causedisease in humans. Earlier this week, Ebright quest ioned the accuracy of Bedford's calculation thatthere are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhanvirology institute - and 2019-nCoV, arguing that the mutation rate may have been different as itpassed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV dataare "consistent with entry into the human population as a natural accident."Shi did not reply to emails from Science, but her longtime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, anew virus, the same story comes out: This is a spillover or the release of an agent or a bioengineeredvirus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yetit's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've justscratched the surface. Within that diversity, there will be some that can infect people and within thatgroup will be some that cause illness."A team of researchers from the Wuhan Institute of Virology and the Eco Health Alliance have trappedbats in caves all over China, like this one in Guangdong, to sample them for coronaviruses.EcoHealth All ianceDaszak and Sh i's group have for 8 years been trapping bats in caves around China to sample theirfeces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 otherspecies. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to theSARS virus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collectedin 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virusfrom Yunnan has high sequence identity with the new one that that's the origin," Daszak says, notingthat only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that oncewe've sampled and sampled and sampled across southern China and central China that we're going tofind many other viruses and some of them will be closer [to 2019-nCoV]."It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If wedon't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreakdies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what thereal origins of this are."Posted in:• Asia/ PacificNIH-002401• Health• Coro navi rusdoi:10 .11 26/science.abb1256Jon CohenJon is a staff writer for Science.• Email Jon• Twit te rDisclaimer : Any third-party material in this email bas been shared for internal use under fair useprovisions of U.S. copyright law, without further verification of its accuracy /veracity . It does notnecessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government.NIH-002402From:Sent :To:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:39:50 +0000Billet, Courtney (NIH/NIAID) [E]Subject:china.Attachme nts:FW: Possible cure medically to the new coronav irus,corona virus,from wuhanmedicalcure.docxNIAID inquiries, pleaseFrom: andrew igla (b)(6)>Se nt: Saturday, February 1, 2020 2:22 AMTo: Fauci, Anthony (NIH/NIAID) [E]_ _____ ('"b'~..(-=6. )>Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china.read t his emai l.From: andrew igla (b)(6)Se nt: Tuesday, 28 January 2020 6:36 PMTo: secretary@hhs .gov <secretary@hhs.gov >Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china .From: andrew igla (b)(6)>Sent : Sunday, 26 January 2020 9:10 PMTo: secretary@ hhs.gov <secretary@hhs .gov>Subject : Possible cure medically to the new coronavirus,corona virus,from wuhan china .For secreta ry Azar th is emai l.From: andrew igla (b)(6)>Sent : Sunday, 26 January 2020 8:59 PMTo: secretary@ HHS.gov <secreta ry@HHS.gov>Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china.NIH-002403From: andrew igla (b)(6)Sent: Sunday, 26 January 2020 1:25This email is to be sent to the doctors treating medically patients in hospitals involvingthe new coronavirus,corona virus, from wuhan china.This email contains the possiblemedical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discoveredfrom an australian friend of the american people,andrew igla.This email is about orally tak ing zovirax and ciproxin together for one day.Orally taking ciproxin,inhibiting gyrase,orally taking zovirax,inhibit ing viral DNA polymerase,together at the same time, stops viral dna moving medically curing viruses in host cellsstoping duplica ting viral infected cells and stoping a virus invading new uninfected cells.Attached document contains possible medical cure to new corona virus from wuhan inchina to help you win over this virus.Dear professor and politican,My name is andrew igla and work as a research science person in denguevirus and anaconda sea snake virus.Attached is a business document for you.Thanks,Andrew igla. melbourne australia.NIH-002404From:Sent:To:Subject:Attachments :Please handle.Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:35:10 +0000Cassetti, Cristina (NIH/NIAID) [E]FW: 2019-nCoVAminopeptidase N inhibitors and Coronaviruses-LANCET 2003.pdfFrom: Kontoyiannis,Dimitrios P _________ Cb _H_6)>Sent: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _______ _.Subject: FW: 2019-nCoVDear Dr Fauci, I enjoyed your recent editorial in JAMA re CoronavirusesAlthough the viral disease is not an area of my expertise, you might want to take a lookat a hypothesis we had proposed, long ago (back in the era of SARS), re the potential ofimmune-modulating Coronavirus infection natural history with blockage ofaminopeptidase N.I am not aware of any studies whether aminopeptidase is a receptor of China 2019-nCoV, though.SincerelyDPKDimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAASTexas 4000 Distinguished Endowed Professor For Cancer ResearchDeputy Head, Division of Internal MedicineThe University of Texas MD Anderson Cancer CenterECMM Diamond Excellence in Mycology Center/www .ecmm.infoAdj Professor Baylor College of MedicineAdj Professor UT School of Public HealthAdj Professor University of HoustonThe informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected fromdisclosure. This e-mail message may contain protected health information (PHI); dissemination of PHIshould comply with applicable federa l and state laws. If you are not the intended recipient, or anauthorized representative of the intended recipient, any further review, disclosure, use, disseminat ion,distribution, or copying of this message or any attachment (or the information contained therein) isstrictly prohibited. If you think that you have received this e-mail message in error, please not ify thesender by return e-mail and delete all references to it and its contents from your systems.NIH-002405From:Sent:To:Subject:Attachments :FYIFauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:34:43 +0000Tabak, Lawrence (NIH/OD) [E)FW: TeleconferenceCoro navirus sequence comparison[l].pdfFrom: Jeremy Farrar (b)(6)>Sent: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------Cc: Drosten , Christian (b)(6); Marion Koopmans(b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes(b)(6) Andrew Rambaut (b)(6) -----~--======~~:;;---:--:-- Krist ian G. Andersen (b)( ; Paul Schreier (b)( ;======-;- Cb(Hb~) (;~ Ferguson, Mike ._ _________ (b)(_6 ) ; Collins, Francis {NIH/OD) [E)Subject: Re: TeleconferenceKristen and Eddie have shared this and will ta lk through it on the call. Thank you.Hope it will help frame the discussions.From: Jeremy Farrar (b)(6)Date: Saturday, 1 February 2020 at 15:341st February (2nd Feb for Eddie)Information and discussion is shared in total confidence and not to be shared until agreement on nextsteps.Dial in details attached.Please mute phones .I will be on email throughout - email Paul or I Paul if any problemsIf you cannot make it, I will phone you afterwards to update .One Hour6am Sydney8pm CETNIH-002406NIH-0024077pm GMT2pm EST11am PST(Hope I have the times right!)Thank you for the series of calls and for agreeing to jo in this call.Agenda• Introduction , focus and desired outcomes - JF• Summary - KA• Comments - EH• Q&A-AII• Summary and next steps - JFKristian AndersonBob Garry - I have not been able to contact Bob. Please forward if you can.Christian DrostenTony FauciMike FergusonRon FouchierEddie HolmesMarion KoopmansStefan PohlmannAndrew RambautPaul SchreierPatrick VallanceFrom:Sent:To:Subject:Kay:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 18:23:07 +0000Kay JohnsonRE: thank you for continuing leadershipThank you for your kind note. Much appreciated.Best regards,TonyFrom: Kay Johnson- ---------- (b)(6) Sent: Saturday, February 1, 2020 9-:1-5- A-M-- -=-,-=, To: Fauci, Anthony (NIH/NIAID) [E)- ------- (b)(6) Subject : thank you for continuing leadershipDear Dr. Fauci - We met long ago when I was a young health policy staff person at theChildren's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around1984-86.When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-91 measlesepidemic and helped to write the measles whitepaper, I had other occasions to hear yourinsights.Since that time, I have frequently heard you on the PBS NewsHour and NPR, I see yourperspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and readJAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly youarticulate the science, the issues for public concern, and options for our nation 's response.While I've worked with many public health leaders and watched others in the media over thepast 35 years of my Maternal and Child Health public policy career, I believe no one is better atcommunications than you. It is in some ways a thank less job. I am writing to say that yourcontinuing leadership and dedication to our nation's health is deeply appreciated by me andmillions of others.Best regards, KayKay JohnsonPresident, Johnson Group Consult ing, Inc.voice: Cb) (6)fax: 802-482-3008Email: (b)(6) ----------NIH-002408From:Sent :To :Cc:Subject:Attachments :Please handle.Fauci, Anthony (NIH/NIAID) [ElSat, 1 Feb 2020 17:56:42 +0000Cassetti, Cristina (NIH/NIAID) [ElConrad, Patricia (NIH/NIAID) [ElFW: article from IIT /India on Coronovirus20200130.2019-nCOV sequence paper.927871vl.full.pdfFrom: WRB Gmail CbH >Sent: Saturday, February 1, 2020 10:27 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)Cc: Hong Cai (b)(6)Subject: article from IIT /India on CoronovirusHi Tony,I hope you are coping with the chaos around coronavirus.I am (b)(6)1 but still active, currently chair of Mesa Biotech,No doubt you have seen, but in case not, I am sending a copy.(b)(4)Hopefully someone at NIH is trying to replicate this study or to find problems with the irmethodology .With best wishes,BillNIH-002409(b) (4)William R. Brody(b)(6) l ohns Hopkins UniversitySalk Institute for Biological StudiesNIH-002410From:Sent :Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 17:54:38 +0000To: Greg Folkers (b)(6)Cc: Conrad, Patricia (NIH/NIAID) [E]Subject: FW: POLITICO: New FDA chief plans for 'the most serious scenarios' ofcoronavirus outbreakWe should make a similar slide for upcoming talks.From: Folkers, Greg (NIH/N IAID) [E)- -------- (b)(6) Se nt: Saturday, February 1, 2020 10:44 AMSubject: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreakEXCLUSIVENew FDA chief plans for 'the most serious scenarios' ofcoronavirus outbreakCBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn.The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ APPhotoBy SARAH OWERMOHLE and SARAH KARLIN-SMITH01/31/2020 04:54 PM ESTUpdated: 01/31/2020 05:28 PM ESTNew FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to letstates safely import drugs. Then the Wuhan coronavirus broke out.The virus was declared a public health emergency by HHS just a few hours after Hahn's exclusiveinterview with POLITICO Friday. That kicks the agency into overdrive in multiple roles - helping speedvaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devicesthe United States needs that are made in China.AdvertisementHahn said there have not been any reports yet of disruption of the supply chain or shortages, but theagency is looking ahead and planning for "what could potentially be the most serious of scenarios." As ofnow FDA inspections in China are being conducted on a case-by-case basis.NIH-002411NIH-002412"We are taking on an individual -by-individual basis what's the regulatory need for anything in China ...versus what are the personnel risks associated," he said.Monitoring the the situation in China could soon get trickier as the State Department expandsmandatory evacuation from affected areas of the country.The coronavirus also broke out in an election year when President Donald Trump wants to deliver on hispromise to bring down drug prices - not traditionally the province of the FDA, a regulatory agencydesigned to focus on safety and efficacy ."If my patients couldn't get access to something because of cost - that was a real problem for me as adoctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows inthe best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer.Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced itsplan to let states import cheaper medicines from Canada - an approach that prior FDA commissionersopposed over fears it would jeopardize the safety of the drug supply. Trump has endorsed letting statessuch as Florida do this.WHO declares globalhealth emergencyThe novel coronavirus that first infectedpeople in Wuhan. China. has spread tomore than 20 other countries, withRussia and the U.K. report ing their firstcases of the viral pneumonia on Jan . 31.7,8186.0652019-nCoVi s a coronav1ruas t.y pe ofvirus similar to the comm°" cold, SARSartd MERS. Ir is spread by close contact 4,593with people who are inleaed. Onestudy suggests men might be moresusceptible to che virus than women.Cases confirmed by WHOASOFJAH.312,01G1,3205812,7989,826282 3146 6Jan. 20 21Cont, ed deaths170 213-17 -25 -"' 5-6 B-O 106- 132- - 23 24 25 26 27 28 29 30 31Sour~s WHOS. outhC hinaM orningP o-it.n ewsr f!ponsBy PattttSOn Clark. POLITICO Pro OataP(llnlPatterson Clark/POLITICO Pro DataPoint"There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing tohave to figure th is one out and balance both of those issues," Hahn said, referring to safety andaffordability.NIH-0024 13NIH-002414The FDA for years has mostly stayed out of the debate around drug prices; the agency doesn't regulatethe cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices downby approving more generics, acknowledging that "the American people are expecting us to do more."Trump has touted the FDA's record on boosting competition via generic approvals .As FDA works on finalizing the importation rule, Hahn said the agency will be open to addressingcriticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome.But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," hesaid.Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of newbrand-name products that are approved with limited data sets, similar to the way CMS decides to coversome medical devices. That approach - known as coverage with evidence development - let s CMScover a new prod uct on the condition that manufacturers keep providing data.FDA has not done that, but new medicines are increasingly being approved on smaller clinical trialswithout hard data on clinical benefits - and can come with six-figure price tags.As an academic, Hahn had co-written an editorial suggesting that payments for newly approvedradiation oncology devices could be linked t o older products unt il enough evidence builds up to showthat the new products are superior. Only then would manufacturers have more pricing leeway."It's a CMS call about coverage with evidence development, but I do think in this world where we areconcerned, and rightfully so, about the cost of medicine and health et cetera, that we should be lookingat all avenues to approach that, " he told POLITICO.Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly toapprove drugs without adequate evidence. But Hahn did not indicate he would put the brakes on."At the end of the day there is this balance between the gold standard and being efficient and gettingth ings in people's hands I'm totally confident in the agency's ability to do that."Hahn must balance all that while leading the FDA's response to t he Wuhan crisis, which has heightenedsome lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents ofcontamination with carcinogens."We have to be concerned about the supply chain to make sure that we have enough of what we need ifthere are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefingThursday for Energy and Commerce committee members with top health officials . The fact that Chinamanufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us tobe reexamining what we're doing in China versus what should be brought back to this country." shesaid.Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers havepressed for a clear FDA framework on selling cannabidiol, the popular hemp and marijuana byproductdecriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused infood, cosmetics and skincare products ."You cannot walk down the street without seeing the products " but there is a dearth of solid data onhow safe and effective CBD actually is, said Hahn.Those CBD challenges have fueled larger discussions about how to better regulate the vast dietarysupplement market, where manufacturers often push legal boundaries by making unverified claimsabout how herbal or homeopathic products can help people."It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to makesure that safe and effective products are in the hands of people."Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily representmy views nor those ofNIAID , NIH, HHS, or the U.S. government .From:Sent:To:Subject :OK. Stay tuned.-----Orig inal Message-----Fauci, Anthony (NIH/N IAID) [ElSat, 1 Feb 2020 17:51 :31 +0000Auchincloss, Hugh (NIH/NIA ID) [ElRE: Continu edFrom : Auchinclos s, Hugh (NlH/N IAJD) [E]...__ ______ (b~<..,.Sent : Saturday, Febrnary 1, 2020 11:47 -A-M-- -~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( >Subject: ContinuedThe paper you sent me says the experim ents were perfonn ed before the gain of function pause but have since beenrev iewed and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gonethrough the P3 framewo rk. She will try to detem1ine if we have any distant ties to this work abroad.Sent from my iPadNIH-0024 15From:Sent:To:Subject :Fauci, Anthony (NIH/NIAID) [ElSat, 1 Feb 2020 17:32:40 +0000Cassetti, Cristina (NIH/NIAID) [ElFW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On ATreatment For The Novel Wuhan CoronavirusPease handle.---<-Origi11alM essa,g,e;--:--;-;...-------~~ From: Amit Gupta (b) ( >S~nt: Saturcl..ay,F e bruary I , 2020 12:2-3 -PM- -----,;..,=.,- ,, To : Fauci , Anthony (NIH/NIAJD) [E] (b)(6) >Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Been Working On A Treahne nt For The NovelWuhan CoronavimsDear Dr. Fauci.Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You area great Scientist and Doctor.Coronavirus update: WHO says prepare for local corona virus outbreaks in other countries;What do you think about this treatment.Regards,AmitSHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the"Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novelnanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles ,that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus."We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. Diwan , PhD,President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the mostrap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen taland international agencies such as the US CDC, WHO, and Chinese CDC to successfu lly develop these treatments,and, if developed , to get them to the patients in the fastest possible time. At this time, the Company does not have acol labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked todevelop a treatment for this virus. We had collaborations with the CDC and USAMRIID in the past. The Companyintends to pursue a relevant collaboration for testing of our drug candidates soon."The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has beenshown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 ."We have already found some lead candida te ligands in our chemical library that can bind to the SARS-CoV spikepro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explainedDr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tentialtreatm ent for the new Wuhan virus. "While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some ofwhich are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates incell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu lviruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrumantiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus whereNIH-0024 16NIH-002417it intends to perform this testing.The Company has its own cGMP-capable drug manufactu ring facility. This highly custom izable faci lity can beemployed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company'sdrug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients .The Company's platform technology has already proven that it can result in safe drugs. The Company's first INDreadyclinical drug candidate , namely NV-HHV- 101, has successfu lly undergone a standard battery of Safety andToxicological testing , as previously disclosed by the Company in press releases and SEC fil ings.The Company is building on its previous work against coronaviruses . The Company's technology relies on copyingthe human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" thatwill bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to ananomicelle, to create a nanoviricide®. It is anticipated that when a virus comes in contact with the nanoviricidc, notonly would it land on the nanoviricide surface, binding to the copious number of ligands presented there, but itwould also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p,harnessing a well known biophysica l phenomenon."It is like a 'Venus-Fly- Trap' for the virus," explained Dr. Diwan.The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copyingthe specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor,and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spiteof mutations.Tn 2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses ingeneral. lt bad developed potential candidates for testing in animal models. The MERS-CoV threat was eclipsed bythe Ebola epide mic of 2015 . The Compa ny developed viable drug candidates against Ebola in a rapid response timeof a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. TheCompany believes that another cycle of optimization would have resulted in a candidate ready for animal testingunder the criteria estab lished by USAMRTJD then.During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity orthe BSL2 virology testing facility, all of which were commissioned after 2015 at its modern campus in Shelton, CT.The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials.This drug candidate, NV-HHV-101, is a skin cream with the treatment of shingles rash as its first indicat ion . It hasshown broad-spectrum activ ity against HSY- I ( cause of "cold sores"), HSV-2 ( cause of "gerutal ulcers"), and VZV(the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les inadults).NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidencethat our platform is capable of creating safe drugs.The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs forclinical supply.The Company's top priority remruns working on its first IND application for NV-HHV-l01. The Company intendsto solicit interest and financing from government agencies in order to accelerate its work on the coronaviruses .The market size for the treatment of shingles is estimated at approximately one billion dollars by various estimates.These estimates take into account the Shingrix® vaccine as well as existing vaccines. About 500,000 to 1 millioncases of shing les occur in the USA alone every year.The market size for our immediate target drugs in the HerpeCide™ program is variously estimated at billions to tensof billions of dollars. The Company believes that its dermal topical cream for the treatment of shing les rash will beNIH-002418its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in theHerpeCide™ program, namely, HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected tofollow the shing les candidate into IND-enabling development and then into human clinical trials . These additionalcandidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value.The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approachenables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - itis designed to "look like" the cell surface to the virus. The nanoviricide® technology enables direct attacks atmultip le points on a virus particle. It is believed that such attacks would lead to the virus particle becomingineffective at infecting cells. Antibodies in contrast attack a virus particle at only a maximum of two attachmentpoints per antibody. In addition, the nanovi ricide technology also simultaneously enables attacking the rapidintracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) withinthe core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of ourknowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, andsimultaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virusinfection.About NanoYiricidesNanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purposenanomaterials for antiviral therapy. The Company's novel nanoviricide® class of drug candidates are designed tospecifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 withits first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugsagainst a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC andherpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, andEbola virus, among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses todtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statementsthat reflect the Company's current expectation regarding future events. Actual events could differ materially andsubstantially from those projected hereiD and depend on a number of factors. Ce11ain statements in this release, andother written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaningof Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You shouldnot place undue reliance on forward-looking statements since they involve known and unknown risks, uncertaintiesand other factors whicb are, in some cases , beyond the Company's control and which could, and likely will,materially affect actual results , levels of activity, performance or achievements. The Company assumes noobligation to publicly update or revise these forward-looking statements for any reason, or to update the reasonsactual results could differ materially from those anticipated in these fo1ward-looking statements, even if newinfonnation becomes available in the future. Important factors that could cause actual results to differ materiallyfrom the company's expectations include, but are not limited to, those factors that are disclosed under the heading"Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securitiesand Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all suchfactors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricideis safe and effective; successful development of our product candidates; our ability to seek and obtain regulatoryapprovals, including with respect to the indications we are seeking; the successful cotmnercialization of our productcandidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . INDapplication refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, andControls".Contact:NanoViricides , Inc.info@nanoviricides.comFrom:Sent :To:Subj ect :At tac hment s:Here it isAnthony S. Fauci, MDDirectorFauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 13 :19:06 +0000Tabak, Lawrence (NIH/OD) [E)FW: IMPORTANTBarie, Shi et al - Natu re medicine - SARS Gain of function.pdfNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301) 496-4409E-mail: (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation. It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives.NIH-002421From :Sent :To:Cc:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 12:43:22 +0000Marston, Hilary (NIH/NIAID) [E]Conrad, Patricia (NIH/NIAID) [E]Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards aresearch roadmap Feb 11-12, 2020 Geneva WHO HQAttachment s: Global Research Forum dv2AMHR AM.PDFWe need to talk about this later in the day .. I am on Conference calls now. I w ill call you later.Apparently Soumya is reaching out separate ly to other people in NIAID.From: SWAMINATHAN, Soumya ----------(b)(6) Se nt: Saturday, February 1, 2020 7:19 AMTo: Fauci, Anthony (NIH/NIAID) [E)_ _____ "("b"")"("=6")Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmapFeb 11-12, 2020 Geneva WHO HQDearTonyI am delighted to inform you that WHO is organizing a global research partners forum on February 11thand 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expectedoutcome is a research roadmap with clearly defined priorit ies and a governance framework to take eacht hematic area forward. Several thematic areas will be considered at the meeting, namely: virus,diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science;animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting willbe critical in consensus building on the most important research questions, as well as in building globalpartnerships and collaborations to take this work forward.This meeting is being organized in partnership with GLOPID Rand is being supported by the Bill andMelinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat withinWHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself.As the head of an agency that would play an impor tant role in addressing this new viral outbreak, eitherby undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. Iapologize for the short not ice, but you will understand that we have had to plan this in the past fewdays, keeping in mind the evolving situation .Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us.Please copy (b)(6) and (b)(6) in your response.With best wishes,SoumyaDr Soumya SwaminathanNIH-002422NIH-002423Chief ScientistPS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry aboutthe short notice!From: Fauci, Anthony (NIH/NIAIO) [E)Sent : Sat, 1 Feb 2020 12:32:57 +0000To: 00~Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards aresearch roadmap Feb 11-12, 2020 Geneva WHO HQAttachme nts: Global Research Forum dv2AMHR AM.PDFCliff:Whom should I nominate? See ye llow highlightTonyFrom: SWAMI NATHAN, Soumya <! (b)(6)Sent : Saturday, February 1, 2020 7:19 AMTo: Fauci, Anthony (NIH/NIAID) [E] <-!---- -(.b..H.,=6)>Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmapFeb 11-12, 2020 Geneva WHO HQDearTonyI am delighted to inform you that WHO is organizing a global research partners forum on February 11thand 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expectedoutcome is a research roadmap with clearly defined priorit ies and a governance framework to take eachthematic area forward. Several thematic areas will be considered at the meeting, namely : virus,diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science;animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting willbe critical in consensus building on the most important research questions, as well as in building globalpartnerships and collaborations to take this work forward .This meeting is being organized in partnership with GLOPID Rand is being supported by the Bill andMelinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat withinWHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself.As the head of an agency that would play an important role in addressing this new viral outbreak, eitherby undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . Iapologize for the short notice, but you will understand that we have had to plan this in the past fewdays, keeping in mind the evolving situation.Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us.Please copy (b)( and (b)(6lin your response.With best wishes,SoumyaDr Soumya SwaminathanNIH-002424NIH-002425Chief ScientistPS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry aboutthe short notice!From: Fauci, Anthony (NIH/NIAIO) [E)Sent:To: (b)(6)Sat, 1 Feb 2020 12:29:36 +0000Auchincloss, Hugh (NIH/NIAID) [C] ---------- Cc: (b )( 6)Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or iginsAs per my prior e-mail.From: Folkers, Greg (NIH/NIAID) [El- -------- (b)(6) Sent: Friday, January 31, 2020 8:43 PMSubject: Science: Mining coronavirus genomes for clues to the outbreak's originsAs part of a long-running effort to see what viruses bats harbor, researchers in China collect one from acave in Guandong.EcoHealth AllianceMining coronavirus genomes for clues to theoutbreak's originsBy Jon CohenJan. 31, 2020, 6:20 PMattaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ...That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viralpathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening theentire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus frompatients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database. These viralgenomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on thefamily tree of related viruses found in bats and other species. They have also given glimpses into whatthis newly discovered virus physically looks like, how it's changing, and how it might be stopped ."One of the biggest takeaway messages [from the viral sequences] is that there was a singleintroduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformaticsspecialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market inNIH-002426Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined withsampling the market's environment for the presence of the virus, is clarifying that it indeed had animportant early role in amplifying the outbreak. The viral sequences, most researchers say, also knockdown the idea the pathogen came from a virology institute in Wuhan.In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to producethe virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convertthe viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study.Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.org,preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences byChinese researchers allowed public health labs around the world to develop their own diagnostics forthe virus, which now has been found in 18 other countries. (Science's news stories on the outbreak canbe found here.)When the first 2019-nCoV sequence became available, researchers placed it on a family tree of knowncoronaviruses-which are abundant and infect many species-and found that it was most closelyrelated to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the WuhanInstitute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar toa bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome(SARS), a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful casethat it jumped into people from a coronavirus in civets that differed from human SARS viruses by as fewas 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" hostspecies-or several-between bats and 2019-nCoV.According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted,dubbed RaTG13, differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded,Bedford has created coronavirus family trees (example below) that include bat, civet, SARS,and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it'seasy to see the differences and similarities between the sequences.)~ -.--... 10 _,. --,---_, - '~< .- F======::~:s:: ;:=-: -u __,,aNIH-002427Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between theviruses with the presumed rate s of mutation in other coronaviruses. So it likely took decades forRaTG13-like viruses to mutate into 2019 -nCoV.Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly hasa link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And thephylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see.100too97,...-----TGEV,---- Mink CoV,..___ FerretC oV.----- Bat CoV COPHE15,----- Scotophifus bat CoV 512.__ __ PEDV.----- Bat CoV HKU10..---- Minlopterus bat CoV 1._ ___ Miniopterus bat CoV HKU8~-- Human CoV NL63---- Bat NL63-related CoV.__ ____ Human CoV 229E---~~ SAOS-CoVRhinolophus bat CoV HKU2Human CoV OC43,...__ _ Murine hepatitis virus---R at CoV HKU24 100,__ __ Human CoV HKU1100,,__ 100 -1 Human MERS-CoVCamel MERS-CoV,....__ Plpistrellus bat CoV HKUS,....__ _ TytonycterisB at CoV HKU4Hedgehog CoV90too SARS -CoV BJ01Civet SARS-CoV SZ3Bat SARSr -GoV WIV1Bat SARSr-CoV SHC014Bat SARSr-CoV L YRa11Bat SARSr-CoV Rf1Bat SARSr-CoV ZC45Bat SARSr-CoV HKU3-1,....__ _ Bat SARSr-CoV BM48-31BetaCoV/Wuhan/W IV0S/20191oo BetaCoV/Wuhan/WIV02 /2019BetaCoV/Wuhan/WIV04/2019BetaCoV/Wuh.in/WlV06 /2019100 BctaCoV/Wuhan/W1V07 /2019Bat CoV RaTG13.__ _____ Bat Hp BetaCoV Zhejiang 2013.___ ___ .----- Rousettusb at CoV HKU9100 Bat CoV GCCOC1------IBV0.1The longer a virus circulates in a human populat ions, the more time it has to develop mutations thatdifferentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differfrom each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But itrema ins a mystery which animal spread the virus to humans. "There's a very large gray area betweenviruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at theNIH-002428U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, andothers species.Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether itwas the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27of the first 41 in one report, 26 of 47 in anot her-were connected to the Wuhan market, but up to 45%,including the earliest handful , were not . This raises the possibility that the initial jump into peoplehappened elsewhere .According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafoodmarket has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoVand all were in the huge market's western portion, which is where wildlife were sold. "The positive testsfrom the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at theUniversity of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence."Such a high rate of positive tests would strongly imply that animals in the market played a key role inthe emergence of the virus."Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, ifany, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really,really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionarybiologist at Scripps Research.One possible explanation for the confusion about where the virus first entered humans is if there was abatch of recently infected animals sold at different marketplaces . Or an infected animal trader couldhave transmitted the virus to different people at different markets . Or, Bedford suggests, those earlycases could have been infected by viruses that didn't easily transmit and sputtered out. "It would behugely helpful to have just a sequence or two from the marketplace [environmental sampling] thatcould illuminate how many zoonoses occurred and when they occurred," Bedford says.A research group sent fecal and other bodily samples from bats they trapped in caves to the WuhanInstitute of Virology to search for coronaviruses.EcoHealth AllianceIn the absence of clear conclusions about the outbreak's origin, theories thrive, and some have beenscientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by theJournal of Medical Virology received substant ial press coverage when it suggested that "snake is themost probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it.Conspiracy theories also abound. A CBC News report about the Canadian government deporting Chinesescientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on socialmedia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute ofNIH-002429Virology, which is the premier lab in China that studies bat and human coronaviruses, has also comeunder fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read aheadline on a story in The Washington Post that focused on the facility.Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a newbiosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway,expressing concerns about accidental infections, which he noted repeatedly happened with lab workershandling SARS in Beijing. Ebright, who has a long history of raising red flags about studies withdangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to aSARS-like virus circulating in Chinese bats to see whether it had the potential to cause disease inhumans. Earlier this week, Ebright questioned t he accuracy of Bedford's calculat ion that there are atleast 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virologyinstitute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed throughdifferent hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent withentry into the human population as a natural accident."Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak ofthe EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a newvirus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus,"Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staringus right in the face. There' s this incredible diversity of viruses in wildlife and we've just scratched thesurface . Within that diversity, there will be some t hat can infect people and within that group wi ll besome that cause il lness."A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trappedbats in caves all over China, like this one in Guangdong, to sample them for coronaviruses.EcoHealth Allia nceDaszak and Shi's group have for 8 years been trapping bats in caves around China to sample their fecesand blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. Theyhave found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARS virus onthe family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from acave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan hashigh sequence identity with the new one that th at's the origin," Daszak says, noting that only a tinyfraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled andsampled and sampled across southern China and central China that we' re going to find many otherviruses and some of them will be closer [to 2019-nCoV] ."NIH-002430It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If wedon't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreakdies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what thereal origins of this are."Posted in;• Asia/Pacific• Health• Coronavirusdoi:10.1126/science .abb1256Jon CohenJon is a staff writer for Science.• Email Jon• Twitt erDisclaimer : Any third-party material in this email has been sbared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily repre sentmy views nor those of NlAID , NIH, HHS , or the U.S. government.NIH-002431From:Sent:To:Cc:Subject :Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 12:29:01 +0000Auchincloss, Hugh (NIH/NIAID) [C](b)(6)IMPORTANT(b)(6) -----------Attachments: Barie, Shi et al - Nature medicine - SARS Gain of function.pdfHugh:It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at7:45 AM with Azar. It likely will be over at 8:45 AM. Read this paper as well as the e-mail thatI will forward to you now. You will have tasks today that must be done.Thanks,TonyAnthony S. Fauci , MDDirectorNational Institute of Allergy and Infectious DiseasesBuilding 31, Room 7A-0331 Center Drive, MSC 2520National Institutes of HealthBethesda , MD 20892-2520Phone : (b)(6)FAX: (301 496-4409E-mail : (b)(6)The information in this e-mail and any of its attachments is confidential and may contain sensitiveinformation . It should not be used by anyone who is not the original intended recipient. If youhave received this e-mail in error please inform the sender and delete it from your mailbox or anyother storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall notaccept liability for any statements made that are the sender's own and not expressly made onbehalf of the NIAID by one of its representatives .NIH-002432From:Sent :To:Cc:Subject:Bob:Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 02:48:59 +0000Kadlec, Robert (OS/ASPR/IO)(b)(6)FW: Science: Mining coronavirus genomes for clues to the outbreak's or iginsThis just came out today. Gives a balanced view.Best,TonyFrom: Folkers, Greg (NIH/NIA ID) [E) (b)(6)>Sent : Friday, January 31, 2020 8:43 PMSubject: Science: Mining coronavirus genomes for clues to the outbreak's originsAs part of a long-running effort to see what viruses bats harbor, researchers in China collect one from acave in Guandong.EcoHealth AllianceMining coronavirus genomes for clues to theoutbreak's originsBy Jon CohenJan. 31, 2020, 6:20 PMattaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ...That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viralpathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening theentire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus frompatients - 53 at last count in the Global Initiative on Sharing All Influenza Data database. These viralgenomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on thefamily tree of related viruses found in bats and other species. They have also given glimpses into whatthis newly discovered vi rus physically looks like, how it's changing, and how it might be stopped .NIH-002433NIH-002434"One of the biggest takeaway messages [from the viral sequences] is that there was a singleintroduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformaticsspecialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market inWuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined withsampling the market's environment for the presence of the virus, is clarifying that it indeed had animportant early role in amplifying the outbreak. The viral sequences, most researchers say, also knockdown the idea the pathogen came from a virology institute in Wuhan.In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to producethe virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convertthe viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study.Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org .preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences byChinese researchers allowed public health labs around the world to develop their own diagnostics forthe virus, which now has been found in 18 other countries. (Science's news stories on the outbreak canbe found here.)When the first 2019-nCoV sequence became available, researchers placed it on a family tree of knowncoronaviruses-which are abundant and infect many species-and found that it was most closelyrelated to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the WuhanInstitute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar toa bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome(SARS), a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful casethat it jumped into people from a coronavirus in civets that differed from human SARS viruses by as fewas 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" hostspecies-or several-between bats and 2019-nCoV.According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted,dubbed RaTG13, differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded,Bedford has created coronavirus family trees (example below) that include bat, civet, SARS,and 2019-nCoV sequences. (The trees are inte ractive-by dragging a computer mouse over them, it'seasy to see the differences and similarities between the sequences.)~-- A . ..,.., ··•-■ -.............. . ,..,.-,,I._I ._ ,__,, ------- r:===~~s =, •ou _.,..,---'I-=='--~"=' ------------------c= -----------1 =.•M.""l'"l _....-. l·. .~_.,·_- .. tf.C-,Xt1 om Cl ,u 014 auBedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between theviruses with the presumed rates of mutation in other coronaviruses. So it likely took decades forRaTG13-like viruses to mutate into 2019-nCoV.Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly hasa link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And thephylogene tic tree from Sh i's bioRxiv paper (below) makes the camel-MERS link easy to see.NIH-0024351009197100.~---TGE V.....--- Mink CoV,__ __ Ferret CoV.....---- Bat CoV CDPHE15.----- Sootophifus bat CoV 512L----PE DV~--- Bat CoV HKU 10Minlopterus bat CoV 1,__ ___ Miniopterus bat CoV HKU8.---- Human CoV NL63---- Bat NL63-related CoV.__ ___ Human CoV 229 E'-------,-,~ SADS-CoVRhfnolophus bat CoV HKU2Human CoV OC43--- Murine hepatitis virus 100 ---R at CoV HKU24---- Huma n CoV HKU1__ 100-1 Human MER S-CoV100Camel MERS-CoVPlplstrell us bat CoV HKUS--- Tytonycteris Bat CoV HKU4~- Hedgehog CoVto100 SARS-CoV 8J01Civet SARS-CoV SZ3Bat SARSr -CoV wrv1Bat SARSr -CoV SHC01 4Bat SARSr-CoV L YRa11Ba1 SARSr-CoV Rf1Bat SARSr-COV ZC45Bat SARSr-CoV HKU3- 1--- Bal SARSr-CoV BM48-31IQOBetaCoV/Wuhan/WlV0S /2019100 Beh1CoV/Wuhan/WIV02 /2019BetaCo V/Wuhan/W IV0-4/2019BetaCo V/Wuhan/W IV06/2019100 BeuCoV/Wuhan/W IV07/2019Bat CoV RaTG13,__ _____ Bat Hp BetaCoV Zhejiang 2013____ ,,...... _ Rousettusb at CoV HKU9100 Bat CoV GCCOC 1------ISVThe longer a virus circulates in a human populat ions, the more time it has to develop mutations thatdifferentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differfrom each other by seven nucleotides at most, this suggests it jumped into humans very recently . But itremains a mystery which animal spread the virus to humans. "There's a very large gray area betweenviruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at theU.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, andothers species.Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether itwas the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%,including the earliest handful , were not. This raises the possibility that the initial jump into peoplehappened elsewhere .NIH-002436According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafoodmarket has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoVand all were in the huge market's western portion, which is where wildlife were sold. "The positive testsfrom the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at theUniversity of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence."Such a high rate of positive tests would strongly imply that animals in the market played a key role inthe emergence of the virus."Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, ifany, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really,really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionarybiologist at Scripps Research.One possible explanation for the confusion about where the virus first entered humans is if there was abatch of recently infected animals sold at different marketplaces. Or an infected animal trader couldhave transmi tted the virus to different people at different markets. Or, Bedford suggests, those earlycases could have been infected by viruses that didn't easily transmit and sputtered out. "It would behugely helpful to have just a sequence or two from the marketplace [environmental sampling] thatcould illuminate how man zoonoses occurred and when they occurred," Bedford says.A research group sent fecal and other bodily samples from bats they trapped in caves to the WuhanInstitute of Virology to search for coronaviruses.EcoHealth AllianceIn the absence of clear conclusions about the outbreak's origin, theories thrive, and some have beenscientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by theJournal of Medical Virology received substant ial press coverage when it suggested that "snake is themost probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it.Conspiracy theories also abound. A CBC News report about the Canadian government deporting Chinesescientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on socialmedia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute ofVirology, which is the premier lab in China that studies bat and human coronaviruses, has also comeunder fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read aheadline on a story in The Washington Post that focused on the facility.Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a newbiosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway,expressing concerns about accidental infections, which he noted repeatedly happened with lab workershandling SARS in Beijing. Ebright, who has a long history of raising red flags about studies withNIH-002437dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to aSARS-like virus circulating in Chinese bats to see whether it had the potential to cause disease inhumans. Earlier this week, Ebright questioned t he accuracy of Bedford's calculat ion that there are atleast 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virologyinstitute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed throughdifferent hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent withentry into the human population as a natural accident."Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak ofthe EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a newvirus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus,"Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staringus right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched thesurface. Within that diversity, there will be some that can infect people and within that group wi ll besome that cause illness."A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trappedbats in caves all over China, like this one in Guangdong, to sample them for coronaviruses .EcoHealth AllianceDaszak and Shi's group have for 8 years been trapping bats in caves around China to sample their fecesand blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. Theyhave found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARS virus onthe family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from acave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan hashigh sequence identity with the new one that that's the origin," Daszak says, noting that only a tinyfraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled andsampled and sampled across southern China and central China that we're going to find many otherviruses and some of them will be closer [to 2019-nCoV]."It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If wedon't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreakdies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what thereal origins of this are."Posted in:• Asia/ Pacific• HealthNIH-002438• Coronav irusdoi :10.1126/science.abb1256Jon CohenJon is a staff writer for Science.• Email Jon• TwitterDisclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisionsof U.S. copyright law, without fm·ther verification of its accuracy /veracity . It does not necessarily repre sentmy views nor those ofNTATD, NTH, HHS , or the U.S. government.NIH-002439From:Sent :To:Subject :Fauci, Anthony (NIH/NIAIO) [E)Sat, 1 Feb 2020 02:46:21 +0000Mascola, John (NIH/VRC) [E)FW: Science: Mining coronavirus genomes for clues to the outbreak's or iginsHere is the Jon Cohen article.From: Folkers, Greg (NIH/NIAID) [E] (b)(6)Sent: Friday, January 31, 2020 8:43 PMSubject : Science: Mining coronavirus genomes for clues to the outbreak's or iginsAs part of a long-running effort to see what viruses bats harbor, researchers in China collect one from acave in Guandong.EcoHealth Allia nceMining coronavirus genomes for clues to theoutbreak's originsBy Jon CohenJan. 31, 2020, 6:20 PMattaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ...That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viralpathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelmi ng China and frightening theentire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus frompatients-53 at last count in the Global Initiative on Sharing All Influenza Data database. These viralgenomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on thefamily tree of related viruses found in bats and other species. They have also given glimpses into whatthis newly discovered vi rus physically looks like, how it's changing, and how it might be stopped ."One of the biggest takeaway messages [from the viral sequences] is that there was a singleintr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformaticsspecialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market inWuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined withsampling the market's environment for the presence of the virus, is clarifying that it indeed had anNIH-002440important early role in amplifying the outbreak. The viral sequences, most researchers say, also knockdown the idea the pathogen came from a virology institute in Wuhan.In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to producethe virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convertthe viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study.Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.org,preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences byChinese researchers allowed public health labs around the world to develop their own diagnostics forthe virus, which now has been found in 18 other countries. (Science's news stories on the outbreak canbe found here.)When the first 2019-nCoV sequence became available, researchers placed it on a family tree of knowncoronaviruses-which are abundant and infect many species-and found that it was most closelyrelated to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the WuhanInstitute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar toa bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome(SARS), a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful casethat it jumped into people from a coronavirus in civets that differed from human SARS viruses by as fewas 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" hostspecies-or several-between bats and 2019-nCoV.According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted,dubbed RaTG13, differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded,Bedford has created coronavirus family trees (example below) that include bat, civet, SARS,and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it'seasy to see the differences and similarities between the sequences.)----_,. ,_, -- ----~~~==:: ~;s;: .= ,uu __,IDBedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between theNIH-002441viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades forRaTG13-like viruses to mutate into 2019-nCoV.Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly hasa link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And thephylogene tic tree from Sh i's bioRxiv paper (below) makes the camel-MERS link easy to see.1009797100,...-----TGEV,---- Mink CoV'----ferret CoV.----- Bat CoV COPHE15,----- Scotophifusb at CoV 512.__ ___ PEDV.----- Bat CoV HKU10..---- Miniopterubsa t CoV 1Miniopterusb at CoV HKU8...---- Human CoV NL63---- Bat NL63-related CoV....__ ___ Human CoV 229E,___ _ ___,..,S,,A.. DS-CoVRhinolophus bat CoV HKU2Human CoV OC43Murine hepatitis virus100 .___ _ Rat CoV HKU24,__ __ Human CoV HKU1100,__•oo~ Human MERS-CoVCamel MERS-CoV'---- Pfplstre/lLJS bat CoV HKU5,__ _ Tytonycteris Bat CoV HKU4....__ _ Hedgehog CoV90too SARS-CoV BJ01Civet SARS-CoV SZ3Bat SARSr-CoV WIV1Bat SARSr-CoV SHC014Bat SARSr-CoV L YRa11Bat SARSr-CoV Rf1Bat SARSr-COV ZC45Bat SARSr-CoV HKU3-1.__ _ Bat SARSr-CoV BM48-31BetaCoV/Wuha nlWIVOS/2O19100 BetaCoV/Wuha nlWIVO2/2O19100 BetaCoV/Wuha n/WIV04/2 019BetaCoV/Wuha n/WIVO6f2O19100 BetaCoVIWuha n/WIV07/2019Bat CoV RaTG13.__ ___ Bat Hp BetaCoV Zhejiang 2013,_____ _ .----- Rousettusb at CoV HKU9.___ ____ ,av 100 Bat CoV GCCOC1Q.1The longer a virus circulates in a human populat ions, the more time it has to develop mutations thatdifferentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differfrom each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But itrema ins a mystery which animal spread the virus to humans. "There's a very large gray area betweenviruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at theU.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, andothers species.NIH-002442Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether itwas the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7of the first 41 in one report, 26 of 47 in another - were connected to the Wuhan market , but up to 45%,including the earliest handful , were not . This raises the possibility that the initial jump into peoplehappened elsewhere .According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafoodmarket has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoVand all were in the huge market's western portion, which is where wildlife were sold. "The positive testsfrom the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at theUniversity of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence."Such a high rate of positive tests would strongly imply that animals in the market played a key role inthe emergence of the virus."Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, ifany, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really,really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionarybiologist at Scripps Research.One possible explanation for the confusion about where the virus first entered humans is if there was abatch of recently infected animals sold at different marketplaces. Or an infected animal trader couldhave transmi tted the virus to different people at different markets. Or, Bedford suggests, those earlycases could have been infected by viruses that didn't easily transmit and sputtered out. "It would behugely helpful to have just a sequence or two from the marketplace [environmental sampling] thatcould illuminate how many zoonoses occurred and when they occurred," Bedford says.A research group sent fecal and other bodily samples from bats they trapped in caves to the WuhanInstitute of Virology to search for coronaviruses.EcoHealth AllianceIn the absence of clear conclusions about the outbreak's origin, theories thrive, and some have beenscientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by theJournal of Medical Virology received substant ial press coverage when it suggested that "snake is themost probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it.Conspiracy theor ies also abound. A CBC News report about the Canadian government deporting Chinesescientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on socialmedia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute ofVirology, which is the premier lab in China that studies bat and human coronaviruses, has also comeNIH-002443under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read aheadline on a story in The Washington Post that focused on the facility.Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a newbiosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway,expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rshandling SARS in Beijing. Ebright, who has a long history of raising red flags about studies withdangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to aSARS-like virus circulating in Chinese bats to see whether it had the potential to cause disease inhumans. Earlier this week, Ebright questioned t he accuracy of Bedford's calculat ion that there are atleast 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virologyinstitute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed throughdifferent hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent withentry into the human population as a natural accident."Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak ofthe EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a newvirus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus,"Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staringus right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched thesurface. Within that diversity, there will be some that can infect people and within that group wi ll besome that cause illness."A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trappedbats in caves all over China, like this one in Guangdong, to sample them for coronaviruses.EcoHealth AllianceDaszak and Shi's group have for 8 years been trapping bats in caves around China to sample their fecesand blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. Theyhave found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARS virus onthe family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from acave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan hashigh sequence identity with the new one that that's the origin," Daszak says, noting that only a tinyfraction of coronaviruses that infect bats have been discovered. " I expect that once we've sampled andsampled and sampled across southern China and central China that we're going to find many otherviruses and some of them will be closer [to 2019-nCoV)."It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If wedon't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreakNIH-002444dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what thereal origins of this are."Posted in:• Asia/Pacific• Health• Coronavirusdoi:10.1126/science .abb1256Jon CohenJon is a staff writer for Science.• Email Jon• TwitterDisclaimer: Any third-party material in this email has been shared for internal use under fair use prov isionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily repre sentmy views nor those of NlAlD, Nill, HHS, or the U.S. government.NIH-002445