Dr. James Barnes Wyngaarden (born 1924)
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James Wyngaarden
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James Wyngaarden
James B. Wyngaarden and David Korn, former Chairman of the National Cancer Advisory Board, National Cancer Institute.
12th Director of the National Institutes of Health
In office
April 29, 1982 – July 31, 1989
President
Preceded by
Succeeded by
Personal details
Born
James Barnes Wyngaarden
October 19, 1924
Died
June 14, 2019 (aged 94)
Alma mater
Scientific career
Fields
purine biosynthesis and the genetics of gout
Institutions
James Barnes Wyngaarden (October 19, 1924 – June 14, 2019) was an American physician, researcher and academic administrator.[3] He was a co-editor of Cecil Textbook of Medicine, one of the leading internal medicine texts, and served as director of National Institutes of Health between 1982 and 1989. He had four daughters and one son.[4]
Wyngaarden was a member of the Royal Swedish Academy of Sciences.[5]
^ "Wyngaarden, James B. (1924-)". Calvin College.
^ Harvey, abner McGehee (1978). The Interurban Clinical Club (1905-1976): a record of achievement in clinical science. Interurban Clinical Club.
^ "Biographical Sketches of the Directors of the National Institutes of Health". Archived from the original on 2007-05-26. Retrieved 2007-02-21.
^ "The Royal Swedish Academy of Sciences: James B. Wyngaarden". Retrieved 2009-05-01.[dead link]
https://profiles.nlm.nih.gov/spotlight/bb/catalog/nlm:nlmuid-101584906X11779-doc
Title:
Letter from Joshua Lederberg to James B. Wyngaarden
Creator:
Recipient:
Wyngaarden, James B., 1924-
Date:
13 January 1982
Location:
Box: 35. Folder: 116
Rights:
Public Domain
Genre:
Format:
Text
Extent:
1 pages
Language:
English
Legacy ID:
BBARON
NLM ID:
Profiles Collection:
The Joshua Lederberg Papers
Shareable Link:
https://profiles.nlm.nih.gov/101584906X11779
Annotation:
Author: Joshua Lederberg. Date Written: February 27, 2000.
KW: Congratulate Jim as new NIH director; re linkage of science
and medicine -- cf. P-263; P-265;
"Few people will understand better than yourself the revolutionary impact
of diagnosis of densely spaced molecular polymorphism: to shift the
base of genetic medicine ever more from the investigation of rare (revealing) syndromes
to the most pervasive aspects of public and preventive health";
jl 2/27/00
https://collections.nlm.nih.gov/ext/document/101584906X11779/PDF/101584906X11779.pdf
1982-01-13-collections-nlm-nih-gov-lederberg-letter-to-wyngaarden-101584906X11779.pdf
1982-01-13-collections-nlm-nih-gov-lederberg-letter-to-wyngaarden-101584906X11779-img-1.jpg
Wyngaarden, James 10/19/1924 - 6/14/2019 Durham, NC DURHAM: James B. Wyngaarden, 94, died peacefully at his home June 14, 2019 following a long illness. Dr. Wyngaarden was a giant in the leadership of medicine during the last half of the twentieth century. He embodied the description of the compleat physician as he advanced medicine through his accomplishments as a scientist, educator, clinician, and administrator. He was a creator and model physician-scientist and was considered by many to be one of the founding fathers of molecular medicine, an approach which seeks to determine the molecular basis of diseases so as to facilitate their treatment and cure. Following a lifetime devoted to medicine, Dr. James B. Wyngaarden will long be regarded as amongst the finest of the greatest generation of physician-scientist leaders of the twentieth century. As a scientist, his research in purine metabolism elucidated the understanding of diseases such as gout, and his work was critical for the development of drugs for their treatment. As an educator, he understood the importance of the physician-scientist and was a leading proponent for training and supporting the careers of these critical contributors to medical progress. He was the first to call attention to the waning interest of many young physicians in pursuing such a career, referring as early as 1979 to the physician scientist as "an endangered species," and took steps to remediate the situation such as starting a special research training program for physicians at Duke University. As a physician-author, he wrote some 250 biochemical research, medical education and science policy papers including co-editing five editions each of "Cecil's Textbook of Medicine" and "The Metabolic Basis of Inherited Disease". As a physician-administrator, he helped train legions of leading scientists, department chairs, and health system heads. He chaired the Department of Medicine at the University of Pennsylvania (1965-1967) and then at Duke University (1967-1982), elevating Duke's Department of Medicine to one of the nation's best. He served as Director of the National Institutes of Health (1982-1989), Associate Director for Life Science in the Office of Science and Technology Policy in the Executive Office of the President (G. H. W. Bush) (1989-1990), Director of the Human Genome Organization (1990-1992), Foreign Secretary of the US National Academy of Sciences (1990-1994), and Assistant Vice Chancellor of the Duke University Medical Center (1991-1994). Throughout his career, Dr. Wyngaarden served on numerous federal and private advisory committees. He was a member of the original Scientific Advisory Committee of the Howard Hughes Medical Institute (1969-1982), on the President's Science Advisory Committee (1972-1973), on the President's Committee for the National Medal of Science (1977-1980), as the Director of the World AIDS Foundation (1987-1989), and as a Principal of the Washington Advisory Group (1994-2002). Dr. Wyngaarden's notable achievements were recognized by his election to the National Academy of Sciences, The National Academy of Medicine, the American Academy of Arts and Sciences, the Royal College of Physicians, and the Swedish Royal Academy of Sciences. Further he received the Anlyan Lifetime Achievement Award from Duke University, the George M. Kober Medal from the Association of American Physicians, and eight Honorary Degrees including one from Duke University. Dr. Wyngaarden was born and raised in East Grand Rapids, Michigan, the second of four children born to the late Prof. Martin Wyngaarden and the late Johanna (Kempers) Wyngaarden. He attended Calvin College and Western Michigan University and earned his medical degree at the University of Michigan in 1948. He married Ethel Vredevoogd in 1946 and over a ten year period, their family grew with five children, including Patricia, Jana, Marty, Lisa, and James B. Wyngaarden, Jr. They raised their family primarily in Durham, NC although they spent 1963-1964 in France while Dr. Wyngaarden was on sabbatical as a Visiting Scientist at the Marie Curie and Pasteur Institutes in Paris. Their marriage lasted 31 years. Dr. Wyngaarden was an accomplished tennis player throughout his life, and as an adult enjoyed skiing, sailing with his adult children, and traveling. He delighted in the continued growth of his family which numbered 18 grandchildren and 11 great-grandchildren at the time of his death. He is survived by his daughters Jana Gandy and her husband William of Edgewater, MD, Marty Krauss and her husband Richard of Cambridge, MA, Lisa Wyngaarden of San Miguel de Allende, Mexico, and his son James B. Jr. and his wife Elizabeth of Durham, NC. In addition to his parents , he was pre-deceased by Lillian (Van Slot), his sister, Martin, his brother, Joanne (De Nooyer), his sister, Ethel (Teer), his former wife, Patricia (Fitzpatrick), his eldest daughter, Brian Rolland, a former son-in-law, and Barbara Walsh Wyngaarden, his daughter-in-law. Over the last several years of declining health, his son Jim devoted himself to meeting all the needs of our father in a loving and deeply respectful relationship. His sisters are forever grateful and awed by the steadfast care Jim provided our father. We also thank the many staff of Vin Rouge who welcomed "Doc", our father, almost nightly to their restaurant. Visiting hours are from 6 pm to 8 pm at Clements Funeral Home in Durham on Friday, June 21. Funeral services will be held on Saturday, June 22 at 2 p.m. at Blacknall Presbyterian Church with Pastor Allan Poole officiating. Burial will follow at Maplewood Cemetery. The family is being assisted by Clements Funeral & Cremation Services, Inc. in Durham. Online condolences may be sent to www.clementsfuneralservice.com.