結構生物化學

• 授課教師：佘亮 / lsheh@thu.edu.tw 

• 課程目標及內涵 (Course Objectives and Contents)

This course will begin by introducing the fundamental biochemical concepts such as the stereochemical aspects of amino acids, peptides, proteins and nucleic acids, receptor-ligand interactions, enzyme-substrate interactions. More advanced topics such as complex enzyme and coenzyme mechanisms,enzyme inhibitors and derivation of equations for competitive enzyme inhibitors, application of enzyme inhibitors as new chemotherapeutic agents, specific molecular interactions of protein-ligand and DNA-small ligand interactions will be taught. 

主要參考書籍/資料 (Textbooks and References)

Papers from major journals: Nature, Science, PNAS, J.Am.Chem.Soc., J.Biol.Chem.