In Additive Manufacturing process, dimensional distortion can be result of numbers of factors such as uneven heat dissipation, shrinkage of the material through the fabrication process, residual stresses, among others. The previously cured layers can be curled or warped by newer layers during the solidification process. Distortion and warpage are pervasive among photopolymerization processes, including material jetting and stereolithography processes. Hence, it is essential that an understanding of the circumstances that result in such distortion be developed and disseminated. Another research direction in the 3D-Bio Manufacturing lab was to design a guideline for dimensional distortion on parts fabricated by material jetting processes. Also, to understand which factors affect the distortion and to identify the type and to quantify amount of distortion under various conditions. We, in the 3D-Bio Manufacturing lab, designed experiments to understand the effect of specimen’s aspect ratio, build orientation, part, and layer thickness parameters in material jetting additive manufacturing on part distortion.