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Welcome to the Robbins Lab!
Welcome to the Robbins Lab!
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News
We welcome graduate student rotations and postdoc applications. Contact us
Noncanonical activation of GLI signaling in SOX2+ cells drives medulloblastoma relapse
MARZENA SWIDERSKA-SYN, JÚLIA MIR-PEDROL, ALEXANDER OLESOLGA SCHLEUGERAPRIL D. SALVADOR, SEAN M. GREINER, CARA SEWARD, FAN YANG, BENJAMIN R. BABCOCK, CHEN SHEN, DANIEL T. WYNN, AVENCIA SANCHEZ-MEJIAS, TIMOTHY R. GERSHON, VANESA MARTIN, HEATHER J. MCCREA, KATHRYN G. LINDSEY, CARSTEN KRIEG, JEZABEL RODRIGUEZ-BLANCO.
A druggable UHRF1/DNMT1/GLI complex regulates Sonic hedgehog dependent tumor growth.
Fan Yang, Jezabel Rodriguez-Blanco, Jun Long, Marzena Swiderska-Syn, Daniel T. Wynn, Bin Li, Chen Shen, Anmada Nayak, Yuguang Ban, Xiaodian Sun, Robert K. Suter, Heather J. McCrea, Anthony J. Capobianco, Nagi G. Ayad*, David J. Robbins*.
The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon
Chen Shen; Anmada Nayak; Leif R. Neitzel; Fan Yang; Bin Li; Charles H. Williams; Charles C. Hong; Yashi Ahmed; Ethan Lee; David J. Robbins.
Protein arginine methyltransferase 5 regulates SHH-subgroup medulloblastoma progression
Wynn DT, Rodriguez-Blanco J, Long J, Yang F, Shen C, Fei D, Tang HY, Hanson D, Robbins DJ.
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling
* Accepted
The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6
* Accepted
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