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Welcome to the Robbins Lab!
Welcome to the Robbins Lab!
From Left to Right: Prerna Singh, Dr. Costa, Dr. Bharti, Dr. Afify, Philip Gregory, Dr. Robbins (in chair), Thomas Rohwetter, Dr. Wynn, Dr. Merugu, Takele Yazew
News
News
Robbins lab is new at Georgetown!
We welcome graduate student rotations and postdoc applications. Contact us
Noncanonical activation of GLI signaling in SOX2+ cells drives medulloblastoma relapse
MARZENA SWIDERSKA-SYN, JÚLIA MIR-PEDROL, ALEXANDER OLESOLGA SCHLEUGERAPRIL D. SALVADOR, SEAN M. GREINER, CARA SEWARD, FAN YANG, BENJAMIN R. BABCOCK, CHEN SHEN, DANIEL T. WYNN, AVENCIA SANCHEZ-MEJIAS, TIMOTHY R. GERSHON, VANESA MARTIN, HEATHER J. MCCREA, KATHRYN G. LINDSEY, CARSTEN KRIEG, JEZABEL RODRIGUEZ-BLANCO.
A druggable UHRF1/DNMT1/GLI complex regulates Sonic hedgehog dependent tumor growth.
Fan Yang, Jezabel Rodriguez-Blanco, Jun Long, Marzena Swiderska-Syn, Daniel T. Wynn, Bin Li, Chen Shen, Anmada Nayak, Yuguang Ban, Xiaodian Sun, Robert K. Suter, Heather J. McCrea, Anthony J. Capobianco, Nagi G. Ayad*, David J. Robbins*.
The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon
Chen Shen; Anmada Nayak; Leif R. Neitzel; Fan Yang; Bin Li; Charles H. Williams; Charles C. Hong; Yashi Ahmed; Ethan Lee; David J. Robbins.
Protein arginine methyltransferase 5 regulates SHH-subgroup medulloblastoma progression
Wynn DT, Rodriguez-Blanco J, Long J, Yang F, Shen C, Fei D, Tang HY, Hanson D, Robbins DJ.
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling
* Accepted
The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6
* Accepted
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