Application of a reflected forward backward splitting method with momentum to a fractional-order lung cancer model

Chinedu Izuchukwu, David Amilo, Khadijeh Sadri, Hao-Ren Yao, and Jen-Chih Yao

Communications in Nonlinear Science and Numerical Simulation 2025

(SCI Q1 IF 3.8)

TreatRAG: A Framework for Personalized Treatment Recommendation

Chao-Chin Liu, Hao-Ren Yao, Der-Chen Chang, and Ophir Frieder

 ACM Conference on Recommender Systems (RecSys) 2025

Forecasting Prescription Efficacy

Hao-Ren Yao, Oskar Mencer, Han-Sun Chiang MD, Der-Chen Chang, and Ophir Frieder

European Conference on Information Retrieval (ECIR) 2025

Distilling Multi-Scale Knowledge for Event Temporal Relation Extraction

Hao-Ren Yao, Luke Breitfeller, Aakanksha Naik, Chunxiao Zhou and Carolyn Rose

ACM International Conference on Information and Knowledge Management (CIKM) 2024

(Full Research Track with Oral presentation, acceptance rate 23%)

A Fractional-Order Model for Optimizing Combination Therapy in Heterogeneous Lung Cancer: Integrating Immunotherapy and Targeted Therapy to Minimize Side Effects

David Amilo, Chinedu Izuchukwu, Khadijeh Sadri Khatouni, and Hao-Ren Yao

Scientific Reports 2024

(SCI Q1 IF 3.8)

Self-supervised Representation Learning on Electronic Health Records with Graph Kernel Infomax

Hao-Ren Yao, Nairen Cao, Katina Russell, Der-Chen Chang, Ophir Frieder, and Jeremy T. Fineman

ACM Transactions on Computing for Healthcare (HEALTH) 2024 

(Invited to oral presentation at IEEE/ACM CHASE 2024)

(SCI Q1 IF 8.0)

Heat kernels on unit spheres and applications to graph kernels

Der-Chen Chang, Ophir Frieder, Chi-Feng Hung, and Hao-Ren Yao

Journal of Nonlinear and Variational Analysis 2023 

(SCI Q1 IF 2.175)

Generalized-Hukuhara Subdifferential Analysis and Its Application in Nonconvex Composite Interval Optimization Problems  

A. Anshika, Debdas Ghosh, Radko Mesiar, Hao-Ren Yao, and Ram Surat Chauhan

Information Sciences 2023 

(SCI Q1 IF 8.233)

Clinical Aligned Interpretable Graph-Based Modeling for Intelligent System in Predictive Medicine

Hao-Ren Yao

Georgetown University, PhD dissertation 2021

The analysis from nonlinear distance metric to kernel-based prescription prediction system

Der-Chen Chang, Ophir Frieder, Chi-Feng Hung, and Hao-Ren Yao

Journal of Nonlinear and Variational Analysis 2021 

(SCI Q1 IF 2.175)

Cross-Global Attention Graph Kernel Network Prediction of Drug Prescription

Hao-Ren Yao, Der-Chen Chang, Ophir Frieder, Wendy Huang, I-Chia Liang and Chi-Feng Hung

ACM Conference on Bioinformatics, Computational Biology, and Health Informatics (ACM-BCB) 2020 

(Full paper with Oral presentation, acceptance rate 31%)

GUIR at SemEval-2020 Task 12: Domain-Tuned Contextualized Models for Offensive Language Detection

Tong Xiang*, Sajad Sotudeh*, Hao-Ren Yao, Sean MacAvaney, Eugene Yang, Nazli Goharian, Ophir Frieder

* equal contribution

SemEval @ COLING 2020

Hate speech detection: Challenges and solutions

Sean MacAvaney, Hao-Ren Yao, Eugene Yang, Katina Russell, Nazli Goharian, Ophir Frieder

PLoS ONE 2019 

(SCI Q1 IF 3.24 - highly cited paper)

Multiple Graph Kernel Fusion Prediction of Drug Prescription

Hao-Ren Yao, Der-Chen Chang, Ophir Frieder, Wendy Huang, and Tian-Shyug Lee

ACM Conference on Bioinformatics, Computational Biology, and Health Informatics (ACM-BCB) 2019 

(Full paper with Oral presentation, acceptance rate 27%)

Graph Kernel Prediction of Drug Prescription

Hao-Ren Yao, Der-Chen Chang, Ophir Frieder, Wendy Huang, and Tian-Shyug Lee

IEEE-EMBS International Conference on Biomedical and Health Informatics (IEEE-BHI) 2019

(Full paper with Oral presentation, acceptance rate 11%) 

On Bochner's theorem and its application to graph kernels

Der-Chen Chang, Ophir Frieder, and Hao-Ren Yao

Journal of Nonlinear and Convex Analysis 2018 

(SCI Q2 IF 1.075)

Topic Participation Algorithm for Social Search Engine Based on Facebook Dataset

Hao-Ren Yao and I-Hsien Ting

MISNC 2014

Generating high-fidelity predictions of changes to coded data records

(Co-Inventor: Liwen Sun, Chenyan Xiong and Ophir Frieder)

Assignee: Carnegie Mellon University

U.S. Patent US12430586B1, September 30, 2022

Method and system for assessing drug efficacy using multiple graph kernel fusion

(Co-Inventor: Ophir Frieder and Der-Chen Chang)

Assignee: Georgetown University

U.S. Patent US12482568B2, November 25, 2025

U.S. Patent US12211623B2, January 28, 2025

U.S. Patent US11869664B2, January 9, 2024

U.S. Patent US11410763B2, August 9, 2022

U.S. Patent US11238966B2, February 1, 2022

Explainable AI-driven prescription prediction technologies

Groq, Inc (Acquired Maxeler Technologies, UK)

License announced on January 2020

• NIH Postdoctoral Intramural Research Training Awards (IRTAs), 2021

• National Science Foundation (NSF) Student Travel Award, IEEE BHI-BSN, 2019

• Presidential Award, National University of Kaohsiung, 2014

• Excellent Graduate, National University of Kaohsiung, 2014

• Valedictorian, National University of Kaohsiung, 2014

• Second Place, South Taiwanese Student Creativity Competition, 2013

• Second Place, Graduation Project Competition, National University of Kaohsiung, 2013

• Second Place, International ICT Innovative Services Contest, 2013

• Speaker, Trends in Social Network Research Taipei Workshop, Academia Sinica, 2013

• First Place, Social Network Analysis Competition, National University of Kaohsiung, 2013

• College Student Research Training Fellowship, ROC National Science Council,  2013