By popular vote in May of 2019, Denver, Colorado became the first U.S. city to decriminalize the use of psilocybin, the psychoactive substance in “magic mushrooms.” Eight U.S. cities and the state of Oregon soon followed suit. Psilocybin has also been given a “breakthrough therapy” designation by the F.D.A., which is expediting its use in clinical trials for the treatment of depression. This represents a shift from the 1970s, when psilocybin was associated with the “counterculture” and designated a Schedule I drug under the Nixon administration. But it may represent as well a wider renaissance of the pursuit of what might be called “mystical experiences” through the use of entheogens. We seek proposals that open up the relationships- -in history, in current practice, in literature, and in ritual--between Catholicism, (neo)mysticism, and mind-altering psychedelic drugs.