Irwin began appearing on television shows as early as age two. She appeared regularly in her father's television shows, including The Crocodile Hunter Diaries, and in the 2002 film The Wiggles: Wiggly Safari in a credited cast role. She is of English and Irish ancestry, with abundance of Irish ancestry on her father's side. Irwin said about being a dual citizen (Australian-American), in an interview with Brisbane Times: "What's really nice is being a dual citizen both here and in the US so I think I get to vote there as well."

When she was 9, Irwin hosted Bindi the Jungle Girl, a children's wildlife documentary TV series. She has also been involved in acting, singing, dancing, game show hosting, and has created two instructional fitness DVDs. She is also known for winning season 21 of Dancing with the Stars (US). She currently stars alongside her mother Terri and her younger brother Robert in Crikey! It’s the Irwins.

Bindi Irwin is the elder of the two children of the late conservationist and television personality Steve Irwin and his conservationist wife, Terri Irwin. Bindi's father, Steve Irwin, was killed by a stingray barb on 4 September 2006 when she was eight years old during the filming of the documentary Ocean's Deadliest.

Her mother Terri is currently the owner of Australia Zoo. Bindi's younger brother is Robert Irwin, a television personality and photographer, and she is the granddaughter of naturalist and herpetologist Bob Irwin. She is married to American professional wakeboarder and a member of staff at Australia Zoo, Chandler Powell.

Irwin has proved to eveyone that girls can do jobs and things that people consider a mans job as she is a zookeeper and some people consider that as a mans job. She has inspired the comunity that if you put your heart and head to something you can truly acheive greatness.