CSIBD and
Broad Immunology Symposium 2021

Center for the Study of Inflammatory Bowel Disease (CSIBD) &
the Center for Computational and Integrative Biology (CCIB) present:
31st Annual Symposium & Workshop
November 18, 2021

&

Broad Immunology Program presents:
2nd Broad Immunology Program Symposium
November 19th, 2021


Schedule of Events

Thursday, November 18th, 2021

31st Center for the Study of Inflammatory Bowel Disease Workshop


8:50 – 9:00 CSIBD Overview - Ramnik J. Xavier, M.D., Director


Session I Innate sensing at the host-microbe interface
(Moderators: Gail Hecht / Cheri Sirois)


9:00 - 9:30 Kate Fitzgerald, Ph.D.
“Mechanisms involved in the restriction of SARS-CoV2 Infection.”


9:30 - 10:00 Feng Shao, Ph.D.
"Pyroptosis in antibacterial & antitumor immunity"


10:00 - 10:30 Hao Wu, Ph.D.
“Trapped in droplets: A new mode of sensing danger”


10:30 - 11:00 Jonathan Kagan, Ph.D.
“Initiation and Regulation of Innate Immunity”


Keynote I

11:00 - 12:00 Jenny Ting, Ph.D.
“Innate immune receptors: their links to adaptive immunity and the microbiome”


12:00-1:00 Break


Session II Microbe engineering and microbial therapies
(Moderators: Curtis Huttenhower, Hera Vlamakis)


1:00 - 1:30 Nicola Segata, Ph.D.
“Metagenomic modelling of fecal microbiota transplantation”


1:30 - 2:00 Ben Boursi, M.D.
"Microbiota and cancer - an ecological journey"


2:00 - 2:30 Matthew Henke, Ph.D.
“Characterization of narrow-spectrum antibiotics from patient isolates of Ruminococcus gnavus"


2:30 - 3:00 Cammie Lesser, M.D., Ph.D.
“Engineered bacteria for the site specific delivery of therapeutics to the gut”


3:00 - 3:30 Justin Sonnenburg, Ph.D.
“Engineering and Rewilding the Gut Microbiome”


3:30 - 4:00 Gautam Dantas, Ph.D.
“Predicting and Combating Biotic and Abiotic Disruptions to Diverse Microbiomes”


4:00 - 5:00 Roundtable: The Path to Microbiome-based Therapies

(co-sponsored by CMIT)


Schedule of Events

Friday, November 19th, 2021

2nd Broad Immunology Symposium


Session III Inflammation and myeloid cell biology
(Moderators: Charles Elson / Jacques Deguine)

9:00 - 9:30 Hilary Finucane, Ph.D.
"Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases"

9:30 - 10:00 Sun Hur, Ph.D.
“Molecular mechanism for self vs. non-self RNA discrimination”

10:00 - 10:30 Hailiang Huang, Ph.D.
“Large-scale sequencing and multi-ancestry genetic analyses identify novel genes and variants associated with IBD”

10:30 - 11:00 Rosandra Kaplan, M.D.
“Myeloid biology in dysregulated microenvironments and therapeutic opportunities”

11:00 - 11:30 Ruslan Medzhitov, Ph.D.
“Nutrient adaptation in the intestine”

11:30 - 12:00 Katrin Andreasson, M.D.
“Immune-metabolic mechanisms of cognitive decline in aging”



12:00 - 1:00 Break


Keynote II

1:00 - 2:00 Richard Flavell, Ph.D., FRS
“Commensal derived metabolites promote pro-inflammatory T cell differentiation and IBD pathogenesis”



Session IV Metabolism and Immunity
(Moderators: Thad Stappenbeck / Andrew Luster)

2:00 - 2:30 Ana Domingos, Ph.D.
“NeuroImmunometabolism”

2:30 - 3:00 Luke O’Neill, Ph.D.
“Immunometabolism meets Immunothrombosis”

3:00 - 3:30 Lydia Lynch, Ph.D.
“Diet, lipids and anti-tumor immunity”

3:30 - 4:00 Hongbo Chi, Ph.D.
“Integrating metabolism with systems immunology in immunity and disease”

4:00 - 4:30 Tracey Simon, M.D.
“Race, Lifestyle and Lipids: Improving Prediction of Hepatocellular Carcinoma”