Haber Lab Publications

2000

Demeter, J., et al. “The DNA Damage Checkpoint Signal in Budding Yeast Is Nuclear Limited.” Molecular Cell, vol. 6, no. 2, Aug. 2000, pp. 487–92. PubMed, https://doi.org/10.1016/s1097-2765(00)00047-2.

Evans, E., et al. “The Saccharomyces Cerevisiae Msh2 Mismatch Repair Protein Localizes to Recombination Intermediates in Vivo.” Molecular Cell, vol. 5, no. 5, May 2000, pp. 789–99. PubMed, https://doi.org/10.1016/s1097-2765(00)80319-6.

Haber, J. E. “Lucky Breaks: Analysis of Recombination in Saccharomyces.” Mutation Research, vol. 451, no. 1–2, June 2000, pp. 53–69. PubMed, https://doi.org/10.1016/s0027-5107(00)00040-3.

Haber, J. E. “Partners and Pathwaysrepairing a Double-Strand Break.” Trends in Genetics: TIG, vol. 16, no. 6, June 2000, pp. 259–64. PubMed, https://doi.org/10.1016/s0168-9525(00)02022-9.

Haber, J. E. “Recombination: A Frank View of Exchanges and Vice Versa.” Current Opinion in Cell Biology, vol. 12, no. 3, June 2000, pp. 286–92. PubMed, https://doi.org/10.1016/s0955-0674(00)00090-9.

Lee, S. E., et al. “Arrest, Adaptation, and Recovery Following a Chromosome Double-Strand Break in Saccharomyces Cerevisiae.” Cold Spring Harbor Symposia on Quantitative Biology, vol. 65, 2000, pp. 303–14. PubMed, https://doi.org/10.1101/sqb.2000.65.303.

Malkova, A., et al. “HO Endonuclease-Induced Recombination in Yeast Meiosis Resembles Spo11-Induced Events.” Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 26, Dec. 2000, pp. 14500–05. PubMed, https://doi.org/10.1073/pnas.97.26.14500.

Richard, G. F., et al. “Recombination-Induced CAG Trinucleotide Repeat Expansions in Yeast Involve the MRE11-RAD50-XRS2 Complex.” The EMBO Journal, vol. 19, no. 10, May 2000, pp. 2381–90. PubMed, https://doi.org/10.1093/emboj/19.10.2381.

Sugawara, N., et al. “DNA Length Dependence of the Single-Strand Annealing Pathway and the Role of Saccharomyces Cerevisiae RAD59 in Double-Strand Break Repair.” Molecular and Cellular Biology, vol. 20, no. 14, July 2000, pp. 5300–09. PubMed, https://doi.org/10.1128/MCB.20.14.5300-5309.2000.

1999

Colaiácovo, M. P., et al. “Removal of One Nonhomologous DNA End during Gene Conversion by a RAD1- and MSH2-Independent Pathway.” Genetics, vol. 151, no. 4, Apr. 1999, pp. 1409–23. PubMed, https://doi.org/10.1093/genetics/151.4.1409.

Haber, J. E. “DNA Recombination: The Replication Connection.” Trends in Biochemical Sciences, vol. 24, no. 7, July 1999, pp. 271–75. PubMed, https://doi.org/10.1016/s0968-0004(99)01413-9.

Haber, J. E. “DNA Repair. Gatekeepers of Recombination.” Nature, vol. 398, no. 6729, Apr. 1999, pp. 665, 667. PubMed, https://doi.org/10.1038/19423.

Haber, J. E. “Sir-Ku-Itous Routes to Make Ends Meet.” Cell, vol. 97, no. 7, June 1999, pp. 829–32. PubMed, https://doi.org/10.1016/s0092-8674(00)80795-3.

Holmes, A., and J. E. Haber. “Physical Monitoring of HO-Induced Homologous Recombination.” Methods in Molecular Biology (Clifton, N.J.), vol. 113, 1999, pp. 403–15. PubMed, https://doi.org/10.1385/1-59259-675-4:403.

Holmes, A. M., and J. E. Haber. “Double-Strand Break Repair in Yeast Requires Both Leading and Lagging Strand DNA Polymerases.” Cell, vol. 96, no. 3, Feb. 1999, pp. 415–24. PubMed, https://doi.org/10.1016/s0092-8674(00)80554-1.

Le, S., et al. “RAD50 and RAD51 Define Two Pathways That Collaborate to Maintain Telomeres in the Absence of Telomerase.” Genetics, vol. 152, no. 1, May 1999, pp. 143–52. PubMed, https://doi.org/10.1093/genetics/152.1.143.

Lee, S. E., et al. “Role of Yeast SIR Genes and Mating Type in Directing DNA Double-Strand Breaks to Homologous and Non-Homologous Repair Paths.” Current Biology: CB, vol. 9, no. 14, July 1999, pp. 767–70. PubMed, https://doi.org/10.1016/s0960-9822(99)80339-x.

Pâques, F., and J. E. Haber. “Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces Cerevisiae.” Microbiology and Molecular Biology Reviews: MMBR, vol. 63, no. 2, June 1999, pp. 349–404. PubMed, https://doi.org/10.1128/MMBR.63.2.349-404.1999.

Richard, G. F., et al. “Double-Strand Break Repair Can Lead to High Frequencies of Deletions within Short CAG/CTG Trinucleotide Repeats.” Molecular & General Genetics: MGG, vol. 261, no. 4–5, June 1999, pp. 871–82. PubMed, https://doi.org/10.1007/s004380050031.

Studamire, B., et al. “Separation-of-Function Mutations in Saccharomyces Cerevisiae MSH2 That Confer Mismatch Repair Defects but Do Not Affect Nonhomologous-Tail Removal during Recombination.” Molecular and Cellular Biology, vol. 19, no. 11, Nov. 1999, pp. 7558–67. PubMed, https://doi.org/10.1128/MCB.19.11.7558.

1998

Bosco, G., and J. E. Haber. “Chromosome Break-Induced DNA Replication Leads to Nonreciprocal Translocations and Telomere Capture.” Genetics, vol. 150, no. 3, Nov. 1998, pp. 1037–47. PubMed, https://doi.org/10.1093/genetics/150.3.1037.

Haber, J. E. “A Locus Control Region Regulates Yeast Recombination.” Trends in Genetics: TIG, vol. 14, no. 8, Aug. 1998, pp. 317–21. PubMed, https://doi.org/10.1016/s0168-9525(98)01501-7.

Haber, J. E. “Mating-Type Gene Switching in Saccharomyces Cerevisiae.” Annual Review of Genetics, vol. 32, 1998, pp. 561–99. PubMed, https://doi.org/10.1146/annurev.genet.32.1.561.

Haber, J. E. “Meiosis: Avoiding Inappropriate Relationships.” Current Biology: CB, vol. 8, no. 23, Nov. 1998, pp. R832-835. PubMed, https://doi.org/10.1016/s0960-9822(07)00524-6.

Haber, J. E. “Meiosis. Searching for a Partner.” Science (New York, N.Y.), vol. 279, no. 5352, Feb. 1998, pp. 823–24. PubMed, https://doi.org/10.1126/science.279.5352.823.

Haber, J. E. “The Many Interfaces of Mre11.” Cell, vol. 95, no. 5, Nov. 1998, pp. 583–86. PubMed, https://doi.org/10.1016/s0092-8674(00)81626-8.

Haber, J. E., and E. J. Louis. “Minisatellite Origins in Yeast and Humans.” Genomics, vol. 48, no. 1, Feb. 1998, pp. 132–35. PubMed, https://doi.org/10.1006/geno.1997.5153.

Lee, S. E., et al. “Saccharomyces Ku70, Mre11/Rad50 and RPA Proteins Regulate Adaptation to G2/M Arrest after DNA Damage.” Cell, vol. 94, no. 3, Aug. 1998, pp. 399–409. PubMed, https://doi.org/10.1016/s0092-8674(00)81482-8.

Nugent, C. I., et al. “Telomere Maintenance Is Dependent on Activities Required for End Repair of Double-Strand Breaks.” Current Biology: CB, vol. 8, no. 11, May 1998, pp. 657–60. PubMed, https://doi.org/10.1016/s0960-9822(98)70253-2.

Pâques, F., et al. “Expansions and Contractions in a Tandem Repeat Induced by Double-Strand Break Repair.” Molecular and Cellular Biology, vol. 18, no. 4, Apr. 1998, pp. 2045–54. PubMed, https://doi.org/10.1128/MCB.18.4.2045.

Umezu, K., et al. “Genetic Analysis of Yeast RPA1 Reveals Its Multiple Functions in DNA Metabolism.” Genetics, vol. 148, no. 3, Mar. 1998, pp. 989–1005. PubMed, https://doi.org/10.1093/genetics/148.3.989.

Wu, C., et al. “Mcm1 Regulates Donor Preference Controlled by the Recombination Enhancer in Saccharomyces Mating-Type Switching.” Genes & Development, vol. 12, no. 11, June 1998, pp. 1726–37. PubMed, https://doi.org/10.1101/gad.12.11.1726.

1997

Haber, J. E. “A Super New Twist on the Initiation of Meiotic Recombination.” Cell, vol. 89, no. 2, Apr. 1997, pp. 163–66. PubMed, https://doi.org/10.1016/s0092-8674(00)80194-4.

Ivanov, E. L., and J. E. Haber. “DNA Repair: RAD Alert.” Current Biology: CB, vol. 7, no. 8, Aug. 1997, pp. R492-495. PubMed, https://doi.org/10.1016/s0960-9822(06)00246-6.

Leung, W., et al. “Gene Targeting by Linear Duplex DNA Frequently Occurs by Assimilation of a Single Strand That Is Subject to Preferential Mismatch Correction.” Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 13, June 1997, pp. 6851–56. PubMed, https://doi.org/10.1073/pnas.94.13.6851.

Pâques, F., and J. E. Haber. “Two Pathways for Removal of Nonhomologous DNA Ends during Double-Strand Break Repair in Saccharomyces Cerevisiae.” Molecular and Cellular Biology, vol. 17, no. 11, Nov. 1997, pp. 6765–71. PubMed, https://doi.org/10.1128/MCB.17.11.6765.

Sugawara, N., et al. “Role of Saccharomyces Cerevisiae Msh2 and Msh3 Repair Proteins in Double-Strand Break-Induced Recombination.” Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 17, Aug. 1997, pp. 9214–19. PubMed, https://doi.org/10.1073/pnas.94.17.9214.

Wu, X., et al. “Rules of Donor Preference in Saccharomyces Mating-Type Gene Switching Revealed by a Competition Assay Involving Two Types of Recombination.” Genetics, vol. 147, no. 2, Oct. 1997, pp. 399–407. PubMed, https://doi.org/10.1093/genetics/147.2.399.

Wu, X., and J. E. Haber. “Cutting and Pasting Chromosomes in Vivo.” Trends in Cell Biology, vol. 7, no. 2, Feb. 1997, p. 48. PubMed, https://doi.org/10.1016/S0962-8924(97)82667-0.

1996

Haber, J. E., and W. Y. Leung. “Lack of Chromosome Territoriality in Yeast: Promiscuous Rejoining of Broken Chromosome Ends.” Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 24, Nov. 1996, pp. 13949–54. PubMed, https://doi.org/10.1073/pnas.93.24.13949.

Ivanov, E. L., et al. “Genetic Requirements for the Single-Strand Annealing Pathway of Double-Strand Break Repair in Saccharomyces Cerevisiae.” Genetics, vol. 142, no. 3, Mar. 1996, pp. 693–704. PubMed, https://doi.org/10.1093/genetics/142.3.693.

Malkova, A., E. L. Ivanov, et al. “Double-Strand Break Repair in the Absence of RAD51 in Yeast: A Possible Role for Break-Induced DNA Replication.” Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 14, July 1996, pp. 7131–36. PubMed, https://doi.org/10.1073/pnas.93.14.7131.

Malkova, A., L. Ross, et al. “Meiotic Recombination Initiated by a Double-Strand Break in Rad50 Delta Yeast Cells Otherwise Unable to Initiate Meiotic Recombination.” Genetics, vol. 143, no. 2, June 1996, pp. 741–54. PubMed, https://doi.org/10.1093/genetics/143.2.741.

Moore, J. K., and J. E. Haber. “Capture of Retrotransposon DNA at the Sites of Chromosomal Double-Strand Breaks.” Nature, vol. 383, no. 6601, Oct. 1996, pp. 644–46. PubMed, https://doi.org/10.1038/383644a0.

Moore, J. K., and J. E. Haber. “Cell Cycle and Genetic Requirements of Two Pathways of Nonhomologous End-Joining Repair of Double-Strand Breaks in Saccharomyces Cerevisiae.” Molecular and Cellular Biology, vol. 16, no. 5, May 1996, pp. 2164–73. PubMed, https://doi.org/10.1128/MCB.16.5.2164.

Seto-Young, D., et al. “Genetic Probing of the First and Second Transmembrane Helices of the Plasma Membrane H(+)-ATPase from Saccharomyces Cerevisiae.” The Journal of Biological Chemistry, vol. 271, no. 1, Jan. 1996, pp. 581–87. PubMed, https://doi.org/10.1074/jbc.271.1.581.

Wu, X., et al. “Mechanism of MAT Alpha Donor Preference during Mating-Type Switching of Saccharomyces Cerevisiae.” Molecular and Cellular Biology, vol. 16, no. 2, Feb. 1996, pp. 657–68. PubMed, https://doi.org/10.1128/MCB.16.2.657.

Wu, X., and J. E. Haber. “A 700 Bp Cis-Acting Region Controls Mating-Type Dependent Recombination along the Entire Left Arm of Yeast Chromosome III.” Cell, vol. 87, no. 2, Oct. 1996, pp. 277–85. PubMed, https://doi.org/10.1016/s0092-8674(00)81345-8.

1995

Anand, S., et al. “Mutations of G158 and Their Second-Site Revertants in the Plasma Membrane H(+)-ATPase Gene (Pma1) in Saccharomyces Cerevisiae.” Biochimica Et Biophysica Acta, vol. 1234, no. 1, Mar. 1995, pp. 127–32. PubMed, https://doi.org/10.1016/0005-2736(94)00281-s.

Haber, J. E. “In Vivo Biochemistry: Physical Monitoring of Recombination Induced by Site-Specific Endonucleases.” BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology, vol. 17, no. 7, July 1995, pp. 609–20. PubMed, https://doi.org/10.1002/bies.950170707.

Ivanov, E. L., and J. E. Haber. “RAD1 and RAD10, but Not Other Excision Repair Genes, Are Required for Double-Strand Break-Induced Recombination in Saccharomyces Cerevisiae.” Molecular and Cellular Biology, vol. 15, no. 4, Apr. 1995, pp. 2245–51. PubMed, https://doi.org/10.1128/MCB.15.4.2245.

Monk, B. C., et al. “The Yeast Plasma Membrane Proton Pumping ATPase Is a Viable Antifungal Target. I. Effects of the Cysteine-Modifying Reagent Omeprazole.” Biochimica Et Biophysica Acta, vol. 1239, no. 1, Oct. 1995, pp. 81–90. PubMed, https://doi.org/10.1016/0005-2736(95)00133-n.

Na, S., et al. “MOP2 (SLA2) Affects the Abundance of the Plasma Membrane H(+)-ATPase of Saccharomyces Cerevisiae.” The Journal of Biological Chemistry, vol. 270, no. 12, Mar. 1995, pp. 6815–23. PubMed, https://doi.org/10.1074/jbc.270.12.6815.

Sugawara, N., et al. “DNA Structure-Dependent Requirements for Yeast RAD Genes in Gene Conversion.” Nature, vol. 373, no. 6509, Jan. 1995, pp. 84–86. PubMed, https://doi.org/10.1038/373084a0.

Wu, X., and J. E. Haber. “MATa Donor Preference in Yeast Mating-Type Switching: Activation of a Large Chromosomal Region for Recombination.” Genes & Development, vol. 9, no. 15, Aug. 1995, pp. 1922–32. PubMed, https://doi.org/10.1101/gad.9.15.1922.

1994

Harris, S. L., et al. “Dominant Lethal Mutations in the Plasma Membrane H(+)-ATPase Gene of Saccharomyces Cerevisiae.” Proceedings of the National Academy of Sciences of the United States of America, vol. 91, no. 22, Oct. 1994, pp. 10531–35. PubMed, https://doi.org/10.1073/pnas.91.22.10531.

Ivanov, E. L., et al. “Mutations in XRS2 and RAD50 Delay but Do Not Prevent Mating-Type Switching in Saccharomyces Cerevisiae.” Molecular and Cellular Biology, vol. 14, no. 5, May 1994, pp. 3414–25. PubMed, https://doi.org/10.1128/mcb.14.5.3414-3425.1994.

Kramer, K. M., et al. “Two Different Types of Double-Strand Breaks in Saccharomyces Cerevisiae Are Repaired by Similar RAD52-Independent, Nonhomologous Recombination Events.” Molecular and Cellular Biology, vol. 14, no. 2, Feb. 1994, pp. 1293–301. PubMed, https://doi.org/10.1128/mcb.14.2.1293-1301.1994.

Louis, E. J., et al. “The Chromosome End in Yeast: Its Mosaic Nature and Influence on Recombinational Dynamics.” Genetics, vol. 136, no. 3, Mar. 1994, pp. 789–802. PubMed, https://doi.org/10.1093/genetics/136.3.789.

Monk, B. C., et al. “Modeling a Conformationally Sensitive Region of the Membrane Sector of the Fungal Plasma Membrane Proton Pump.” Journal of Bioenergetics and Biomembranes, vol. 26, no. 1, Feb. 1994, pp. 101–15. PubMed, https://doi.org/10.1007/BF00763222.

Seto-Young, D., et al. “Mutational Analysis of the First Extracellular Loop Region of the H(+)-ATPase from Saccharomyces Cerevisiae.” The Journal of Biological Chemistry, vol. 269, no. 39, Sept. 1994, pp. 23988–95.

Wilson, J. H., et al. “The Frequency of Gene Targeting in Yeast Depends on the Number of Target Copies.” Proceedings of the National Academy of Sciences of the United States of America, vol. 91, no. 1, Jan. 1994, pp. 177–81. PubMed, https://doi.org/10.1073/pnas.91.1.177.

1993

Haber, J. E., et al. “Rapid Kinetics of Mismatch Repair of Heteroduplex DNA That Is Formed during Recombination in Yeast.” Proceedings of the National Academy of Sciences of the United States of America, vol. 90, no. 8, Apr. 1993, pp. 3363–67. PubMed, https://doi.org/10.1073/pnas.90.8.3363.

Harris, S., et al. “Gene Conversions and Crossing over during Homologous and Homeologous Ectopic Recombination in Saccharomyces Cerevisiae.” Genetics, vol. 135, no. 1, Sept. 1993, pp. 5–16. PubMed, https://doi.org/10.1093/genetics/135.1.5.

Kramer, K. M., and J. E. Haber. “New Telomeres in Yeast Are Initiated with a Highly Selected Subset of TG1-3 Repeats.” Genes & Development, vol. 7, no. 12A, Dec. 1993, pp. 2345–56. PubMed, https://doi.org/10.1101/gad.7.12a.2345.

Na, S., et al. “Characterization of Yeast Plasma Membrane H(+)-ATPase Mutant Pma1-A135V and Its Revertants.” The Journal of Biological Chemistry, vol. 268, no. 16, June 1993, pp. 11792–97.

1992

Fishman-Lobell, J., et al. “Two Alternative Pathways of Double-Strand Break Repair That Are Kinetically Separable and Independently Modulated.” Molecular and Cellular Biology, vol. 12, no. 3, Mar. 1992, pp. 1292–303. PubMed, https://doi.org/10.1128/mcb.12.3.1292-1303.1992.

Fishman-Lobell, J., and J. E. Haber. “Removal of Nonhomologous DNA Ends in Double-Strand Break Recombination: The Role of the Yeast Ultraviolet Repair Gene RAD1.” Science (New York, N.Y.), vol. 258, no. 5081, Oct. 1992, pp. 480–84. PubMed, https://doi.org/10.1126/science.1411547.

Haber, J. E. “Exploring the Pathways of Homologous Recombination.” Current Opinion in Cell Biology, vol. 4, no. 3, June 1992, pp. 401–12. PubMed, https://doi.org/10.1016/0955-0674(92)90005-w.

Haber, J. E. “Homologue Sweet Homologue.” Current Biology: CB, vol. 2, no. 9, Sept. 1992, pp. 483–85. PubMed, https://doi.org/10.1016/0960-9822(92)90669-2.

Haber, J. E. “Mating-Type Gene Switching in Saccharomyces Cerevisiae.” Trends in Genetics: TIG, vol. 8, no. 12, Dec. 1992, pp. 446–52. PubMed, https://doi.org/10.1016/0168-9525(92)90329-3.

Louis, E. J., and J. E. Haber. “The Structure and Evolution of Subtelomeric Y’ Repeats in Saccharomyces Cerevisiae.” Genetics, vol. 131, no. 3, July 1992, pp. 559–74. PubMed, https://doi.org/10.1093/genetics/131.3.559.

Perlin, D. S., et al. “Genetic Probing of the Yeast Plasma Membrane H(+)-ATPase.” Acta Physiologica Scandinavica. Supplementum, vol. 607, 1992, pp. 183–92.

Plessis, A., et al. “Site-Specific Recombination Determined by I-SceI, a Mitochondrial Group I Intron-Encoded Endonuclease Expressed in the Yeast Nucleus.” Genetics, vol. 130, no. 3, Mar. 1992, pp. 451–60. PubMed, https://doi.org/10.1093/genetics/130.3.451.

Sugawara, N., and J. E. Haber. “Characterization of Double-Strand Break-Induced Recombination: Homology Requirements and Single-Stranded DNA Formation.” Molecular and Cellular Biology, vol. 12, no. 2, Feb. 1992, pp. 563–75. PubMed, https://doi.org/10.1128/mcb.12.2.563-575.1992.

1991

Haber, J. E., et al. “The Frequency of Meiotic Recombination in Yeast Is Independent of the Number and Position of Homologous Donor Sequences: Implications for Chromosome Pairing.” Proceedings of the National Academy of Sciences of the United States of America, vol. 88, no. 4, Feb. 1991, pp. 1120–24. PubMed, https://doi.org/10.1073/pnas.88.4.1120.

Harris, S. L., et al. “Evidence for Coupling between Membrane and Cytoplasmic Domains of the Yeast Plasma Membrane H(+)-ATPase. An Analysis of Intragenic Revertants of Pma1-105.” The Journal of Biological Chemistry, vol. 266, no. 36, Dec. 1991, pp. 24439–45.

Louis, E. J., and J. E. Haber. “Evolutionarily Recent Transfer of a Group I Mitochondrial Intron to Telomere Regions in Saccharomyces Cerevisiae.” Current Genetics, vol. 20, no. 5, Nov. 1991, pp. 411–15. PubMed, https://doi.org/10.1007/BF00317070.

Ray, B. L., et al. “Heteroduplex Formation and Mismatch Repair of the ‘Stuck’ Mutation during Mating-Type Switching in Saccharomyces Cerevisiae.” Molecular and Cellular Biology, vol. 11, no. 10, Oct. 1991, pp. 5372–80. PubMed, https://doi.org/10.1128/mcb.11.10.5372-5380.1991.

Ray, B. L., et al. “The TSM1 Gene of Saccharomyces Cerevisiae Overlaps the MAT Locus.” Current Genetics, vol. 20, no. 1–2, July 1991, pp. 25–31. PubMed, https://doi.org/10.1007/BF00312761.

Publications from 1981 to 1990.  <-Back--Next->