Haber Lab Publications

2017
Anand, Ranjith, et al. “Rad51-Mediated Double-Strand Break Repair and Mismatch Correction of Divergent Substrates.” Nature, vol. 544, no. 7650, 20 2017, pp. 377–80. PubMed, https://doi.org/10.1038/nature22046.

Botchkarev, Vladimir V., et al. “The Budding Yeast Polo-like Kinase Localizes to Distinct Populations at Centrosomes during Mitosis.” Molecular Biology of the Cell, vol. 28, no. 8, Apr. 2017, pp. 1011–20. PubMed, https://doi.org/10.1091/mbc.E16-05-0324.

Eapen, Vinay V., et al. “A Pathway of Targeted Autophagy Is Induced by DNA Damage in Budding Yeast.” Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 7, 14 2017, pp. E1158–67. PubMed, https://doi.org/10.1073/pnas.1614364114.

Mehta, Anuja, et al. “Homology Requirements and Competition between Gene Conversion and Break-Induced Replication during Double-Strand Break Repair.” Molecular Cell, vol. 65, no. 3, Feb. 2017, pp. 515-526.e3. PubMed, https://doi.org/10.1016/j.molcel.2016.12.003.

Wang, Ruoxi W., et al. “Position Effects Influencing Intrachromosomal Repair of a Double-Strand Break in Budding Yeast.” PloS One, vol. 12, no. 7, 2017, p. e0180994. PubMed, https://doi.org/10.1371/journal.pone.0180994.

2016

Avşaroğlu, Barış, et al. “Chromosome-Refolding Model of Mating-Type Switching in Yeast.” Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 45, Nov. 2016, pp. E6929–38. PubMed, https://doi.org/10.1073/pnas.1607103113.

Haber, James E. “A Life Investigating Pathways That Repair Broken Chromosomes.” Annual Review of Genetics, vol. 50, Nov. 2016, pp. 1–28. PubMed, https://doi.org/10.1146/annurev-genet-120215-035043.

Haber, James E. “The Rule of Three.” Nature Reviews. Molecular Cell Biology, vol. 17, no. 6, 2016, p. 333. PubMed, https://doi.org/10.1038/nrm.2016.57.

Jain, Suvi, Neal Sugawara, and James E. Haber. “Role of Double-Strand Break End-Tethering during Gene Conversion in Saccharomyces Cerevisiae.” PLoS Genetics, vol. 12, no. 4, Apr. 2016, p. e1005976. PubMed, https://doi.org/10.1371/journal.pgen.1005976.

Jain, Suvi, Neal Sugawara, Anuja Mehta, et al. “Sgs1 and Mph1 Helicases Enforce the Recombination Execution Checkpoint During DNA Double-Strand Break Repair in Saccharomyces Cerevisiae.” Genetics, vol. 203, no. 2, 2016, pp. 667–75. PubMed, https://doi.org/10.1534/genetics.115.184317.

Jasin, Maria, and James E. Haber. “The Democratization of Gene Editing: Insights from Site-Specific Cleavage and Double-Strand Break Repair.” DNA Repair, vol. 44, 2016, pp. 6–16. PubMed, https://doi.org/10.1016/j.dnarep.2016.05.001.

Klionsky, Daniel J., et al. “Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition).” Autophagy, vol. 12, no. 1, 2016, pp. 1–222. PubMed, https://doi.org/10.1080/15548627.2015.1100356.

Lee, Cheng-Sheng, et al. “Chromosome Position Determines the Success of Double-Strand Break Repair.” Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 2, Jan. 2016, pp. E146-154. PubMed, https://doi.org/10.1073/pnas.1523660113.

Nakajima, Yuko, and James E. Haber. “Chromosomes at Loose Ends.” Nature Cell Biology, vol. 18, no. 3, Mar. 2016, pp. 257–59. PubMed, https://doi.org/10.1038/ncb3321.

Tsabar, Michael, Julian Haase, et al. “A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere.” PLoS Genetics, vol. 12, no. 4, Apr. 2016, p. e1006021. PubMed, https://doi.org/10.1371/journal.pgen.1006021.

Tsabar, Michael, David P. Waterman, et al. “Asf1 Facilitates Dephosphorylation of Rad53 after DNA Double-Strand Break Repair.” Genes & Development, vol. 30, no. 10, 15 2016, pp. 1211–24. PubMed, https://doi.org/10.1101/gad.280685.116.

Tsabar, Michael, Wade M. Hicks, et al. “Re-Establishment of Nucleosome Occupancy during Double-Strand Break Repair in Budding Yeast.” DNA Repair, vol. 47, 2016, pp. 21–29. PubMed, https://doi.org/10.1016/j.dnarep.2016.09.005.

Yimit, Askar, et al. “MTE1 Functions with MPH1 in Double-Strand Break Repair.” Genetics, vol. 203, no. 1, 2016, pp. 147–57. PubMed, https://doi.org/10.1534/genetics.115.185454.

2015

Ferrari, Matteo, et al. “Functional Interplay between the 53BP1-Ortholog Rad9 and the Mre11 Complex Regulates Resection, End-Tethering and Repair of a Double-Strand Break.” PLoS Genetics, vol. 11, no. 1, Jan. 2015, p. e1004928. PubMed, https://doi.org/10.1371/journal.pgen.1004928.

Haber, James E. “Deciphering the DNA Damage Response.” Cell, vol. 162, no. 6, Sept. 2015, pp. 1183–85. PubMed, https://doi.org/10.1016/j.cell.2015.08.034.

Haber, James E. “TOPping off Meiosis.” Molecular Cell, vol. 57, no. 4, Feb. 2015, pp. 577–81. PubMed, https://doi.org/10.1016/j.molcel.2015.02.004.

Lee, Cheng-Sheng, and James E. Haber. “Mating-Type Gene Switching in Saccharomyces Cerevisiae.” Microbiology Spectrum, vol. 3, no. 2, Apr. 2015, pp. MDNA3-0013–2014. PubMed, https://doi.org/10.1128/microbiolspec.MDNA3-0013-2014.

Tsabar, Michael, Vinay V. Eapen, et al. “Caffeine Impairs Resection during DNA Break Repair by Reducing the Levels of Nucleases Sae2 and Dna2.” Nucleic Acids Research, vol. 43, no. 14, Aug. 2015, pp. 6889–901. PubMed, https://doi.org/10.1093/nar/gkv520.

Tsabar, Michael, Jennifer M. Mason, et al. “Caffeine Inhibits Gene Conversion by Displacing Rad51 from SsDNA.” Nucleic Acids Research, vol. 43, no. 14, Aug. 2015, pp. 6902–18. PubMed, https://doi.org/10.1093/nar/gkv525.

2014

Anand, Ranjith P., et al. “Chromosome Rearrangements via Template Switching between Diverged Repeated Sequences.” Genes & Development, vol. 28, no. 21, Nov. 2014, pp. 2394–406. PubMed, https://doi.org/10.1101/gad.250258.114.

Avşaroğlu, Barış, et al. “Effect of Chromosome Tethering on Nuclear Organization in Yeast.” PloS One, vol. 9, no. 7, 2014, p. e102474. PubMed, https://doi.org/10.1371/journal.pone.0102474.

Braberg, Hannes, et al. “Quantitative Analysis of Triple-Mutant Genetic Interactions.” Nature Protocols, vol. 9, no. 8, Aug. 2014, pp. 1867–81. PubMed, https://doi.org/10.1038/nprot.2014.127.

Costantino, Lorenzo, et al. “Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells.” Science (New York, N.Y.), vol. 343, no. 6166, Jan. 2014, pp. 88–91. PubMed, https://doi.org/10.1126/science.1243211.

Lee, Cheng-Sheng, et al. “Dynamics of Yeast Histone H2A and H2B Phosphorylation in Response to a Double-Strand Break.” Nature Structural & Molecular Biology, vol. 21, no. 1, Jan. 2014, pp. 103–09. PubMed, https://doi.org/10.1038/nsmb.2737.

Mehta, Anuja, and James E. Haber. “Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair.” Cold Spring Harbor Perspectives in Biology, vol. 6, no. 9, Aug. 2014, p. a016428. PubMed, https://doi.org/10.1101/cshperspect.a016428.

Tsaponina, Olga, and James E. Haber. “Frequent Interchromosomal Template Switches during Gene Conversion in S. Cerevisiae.” Molecular Cell, vol. 55, no. 4, Aug. 2014, pp. 615–25. PubMed, https://doi.org/10.1016/j.molcel.2014.06.025.

2013

Anand, Ranjith P., et al. “Break-Induced DNA Replication.” Cold Spring Harbor Perspectives in Biology, vol. 5, no. 12, Dec. 2013, p. a010397. PubMed, https://doi.org/10.1101/cshperspect.a010397.

Dotiwala, Farokh, et al. “DNA Damage Checkpoint Triggers Autophagy to Regulate the Initiation of Anaphase.” Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 1, Jan. 2013, pp. E41-49. PubMed, https://doi.org/10.1073/pnas.1218065109.

Eapen, Vinay V., and James E. Haber. “DNA Damage Signaling Triggers the Cytoplasm-to-Vacuole Pathway of Autophagy to Regulate Cell Cycle Progression.” Autophagy, vol. 9, no. 3, Mar. 2013, pp. 440–41. PubMed, https://doi.org/10.4161/auto.23280.

Haber, James E., et al. “Systematic Triple-Mutant Analysis Uncovers Functional Connectivity between Pathways Involved in Chromosome Regulation.” Cell Reports, vol. 3, no. 6, June 2013, pp. 2168–78. PubMed, https://doi.org/10.1016/j.celrep.2013.05.007.

Liebman, Susan W., and James E. Haber. “Retrospective. Fred Sherman (1932-2013).” Science (New York, N.Y.), vol. 342, no. 6162, Nov. 2013, p. 1059. PubMed, https://doi.org/10.1126/science.1248055.

Saini, Natalie, et al. “Migrating Bubble during Break-Induced Replication Drives Conservative DNA Synthesis.” Nature, vol. 502, no. 7471, Oct. 2013, pp. 389–92. PubMed, https://doi.org/10.1038/nature12584.

Tsabar, Michael, and James E. Haber. “Chromatin Modifications and Chromatin Remodeling during DNA Repair in Budding Yeast.” Current Opinion in Genetics & Development, vol. 23, no. 2, Apr. 2013, pp. 166–73. PubMed, https://doi.org/10.1016/j.gde.2012.11.015.

2012

Eapen, Vinay V., et al. “The Saccharomyces Cerevisiae Chromatin Remodeler Fun30 Regulates DNA End Resection and Checkpoint Deactivation.” Molecular and Cellular Biology, vol. 32, no. 22, Nov. 2012, pp. 4727–40. PubMed, https://doi.org/10.1128/MCB.00566-12.

Haber, James E. “Mating-Type Genes and MAT Switching in Saccharomyces Cerevisiae.” Genetics, vol. 191, no. 1, May 2012, pp. 33–64. PubMed, https://doi.org/10.1534/genetics.111.134577.

Li, Jin, et al. “Regulation of Budding Yeast Mating-Type Switching Donor Preference by the FHA Domain of Fkh1.” PLoS Genetics, vol. 8, no. 4, 2012, p. e1002630. PubMed, https://doi.org/10.1371/journal.pgen.1002630.

Malkova, Anna, and James E. Haber. “Mutations Arising during Repair of Chromosome Breaks.” Annual Review of Genetics, vol. 46, 2012, pp. 455–73. PubMed, https://doi.org/10.1146/annurev-genet-110711-155547.

Sugawara, Neal, and James E. Haber. “Monitoring DNA Recombination Initiated by HO Endonuclease.” Methods in Molecular Biology (Clifton, N.J.), vol. 920, 2012, pp. 349–70. PubMed, https://doi.org/10.1007/978-1-61779-998-3_25.

2011

Coïc, Eric, et al. “Dynamics of Homology Searching during Gene Conversion in Saccharomyces Cerevisiae Revealed by Donor Competition.” Genetics, vol. 189, no. 4, Dec. 2011, pp. 1225–33. PubMed, https://doi.org/10.1534/genetics.111.132738.

Haber, James E. “QnAs with James E. Haber.” Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 14, Apr. 2011, p. 5479. PubMed, https://doi.org/10.1073/pnas.1103328108.

Hicks, Wade M., et al. “Real-Time Analysis of Double-Strand DNA Break Repair by Homologous Recombination.” Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 8, Feb. 2011, pp. 3108–15. PubMed, https://doi.org/10.1073/pnas.1019660108.

Kim, Jung-Ae, et al. “Protein Phosphatases Pph3, Ptc2, and Ptc3 Play Redundant Roles in DNA Double-Strand Break Repair by Homologous Recombination.” Molecular and Cellular Biology, vol. 31, no. 3, Feb. 2011, pp. 507–16. PubMed, https://doi.org/10.1128/MCB.01168-10.

Publications from 2001 to 2010.  <-Back--Next->