Dr.K.S.Santhy

• Senior Research Fellowship,CSIR, New Delhi-1994

• Post Doctoral Fellowship,Andong National University, Republic of Korea,2009 – 2010

• BPA Certificate1995 - Academy of Environmental Biology, Muzaffarnagar,India for Best Paper presentation

• Best Poster presentation award -National Symposium on Recent trends in Applied Biology,2004,Avinashilingam University for women

• Best NSS Programme Officer Award, 2006 - 2007,Avinashilingam University for women,Coimbatore

•  Best NSS Unit Award for NSS Program Officer, 2012 - 2013,Avinashilingam University for women,Coimbatore

•  Best Paper presentation award -International Conference on Conservation strategies for Bio resources-2013,PSGR Krishnammal College for Women, Coimbatore

• First Prize in Photography-World Food Day Celebration,2014-Avinashilingam University for women,Coimbatore

•  Best paper  presentation-National Seminar on Emerging Trends in Phytopharmaceuticals,2017,Vimala College, Thrissur, Kerala

• Principal Investigator

• Characterization and Molecular docking studies of the plant, Alpinia galanga,2017,Enovate Biolife Pvt. Ltd., 2,50,000/-

• Creating awareness among the tribal women of Maruthamalai on the pharmacognostic properties of Rudraksham tree, Elaecarpus sp.,UGC (in house) 2016, Rs.30,000/-

• Integrated analysis of gene expression and genome wide DNA methylation for uterine leomyoma prediction:an association rule mining approach,DST-CURIE-AI Facility,Avinashilingam Institute for Home Science and Higher Education for Women,Coimbatore (Inhouse), 2019.Rs.30,000/-

• In silico approach to analyze the disease associated nsSNPs of MMP2 Protein, Technology Enabling Centre (TEC), Mizoram

University sponcered by DST, New Delhi,2020.Rs.32,000/-

TNSCST Student projects

• Screening and evaluation of mutagenicity in the chosen samples of Noyyal river belt,TNSCST,Rs.5000/-

• Monitoring mutagens on water samples in Salmonella microsome Assay in the presence of S9 fraction at Noyyal River Belt,TNSCST,Rs.5000/-

• Assessment of tumor response to multimodalities of treatment in bladder cancer patients using Comet assay,TNSCST,Rs.5000/-

Book Chapters : 11

1. Deepika, E, Gunavathi, V. and Santhy, K.S. Phytotherapeutical wealth of Catharanthus roseus: A Review. Environment and Sustainable Development Problems Prospects and Mitigation(ESDPPM). 978-93-94779-43-3, Year 2022.

2. Febby, Payva. and Santhy, K.S. Role of Bioinformatics in target identification and differentiation of papillary thyroid carcinoma: A study based on GEO dataset . Trends in Advanced Biology. 978-81-956634-0-8, Year 2022.

3. Tharani, M., Gunavathi, V.,  Deepika, E. and  Santhy, K.S. Antioxidant and Cytotoxic Effects of Methanol Extracts of Sesbania grandiflora Flower. Environment and Sustainable Development Problems Prospects and Mitigation(ESDPPM). 978-93-94779-43-3, Year 2022.

4. Febby, Payva. and Santhy, K.S. Role of Bioinformatics in target identification and differentiation of follicular thyroid neoplasms. International Conference Proceedings- Infectious Diseases in an Era of Vaccines. 978-93-5566-309-2, Year 2021.

5. Valsala, P., Gunavathi, V.  and Santhy, K.S. Evaluation of Biochemical Parameters and Antioxidant Activity of Alpha Terpineol on DMBA Induced Rats. Environment and Development (An Integrated Approach). 978-93-90847-17-4, Year 2021.

6. Zeenath, Gunavathi, V.  and Santhy, K.S. Antitumor activity of Allicin on Lung Cancer in Benzopyrene induced Swiss Albino Mice Model. Environment and Development ( An Integrated Approach). 978-93-90847-17-4, Year 2021.

7. Deepika, E,  Gunavathi, P., Jenifer and Santhy, K.S. Syzygium cumini : an overview of traditional and therapeutic uses. Recent trends in applied sciences and computing engineering. 978-81-950236-3-9, Year 2021

8. Santhy,K.S. and Sreejaya,B.Histopathological study on effect of Acorus calamusL. rhizome on liver and kidney of DAL induced Swiss albino mice., Proceedings of ICMR Sponsored National Conference on Challenging Issues and Technological Approaches in Medicine - CITAM.,81-8446-755-9.,Year: 2016. 

9. Santhy,K.S. and Meena J. Evaluation of the anti-genotoxic effect of methanolic extract of Cyclea peltata in the peripheral blood lymphocytes, Revamping Microbial Biotechnology, Publication Division, ManonmaniamSundaranar University, Tirunelveli.,978-93-81402-35-1,Year: 2016

10. Santhy. K.S. and  Geetha.B., Anticancer activity of Methanol extract of Green tea against cervical cancer (Medicinal plants: Phytochemistry, Pharmacology and Therapeutics).,Daya Publishing House, Astral International Pvt. Ltd., New Delhi.,978-93-5124-704-3.,Year: 2016.

11. Santhy. K.S. and Srividya.M.,Antigenotoxic potential of Punica granatum in Breast cancer patients (Medicinal plants: Phytochemistry, Pharmacology and Therapeutics).,Daya Publishing House, Astral International Pvt. Ltd., New Delhi.,978-93-5124-704-3.,Year: 2016

Journal Publications :84

1. 1. R James, KN Subramanyam, F Payva, AP E, VK TV, V Sivaramakrishnan, In-silico analysis predicts disruption of normal angiogenesis as a causative factor in osteoporosis pathogenesis. BMC Genomic Data 2025 (1), 85

   2. Siva Sankari G.;James R.;Payva F.;Sivaramakrishnan V.;Vineeth Kumar T.V.;Kanchi S.;Santhy K.S.  Computational analysis of sodium-dependent phosphate transporter SLC20A1/PiT1 gene identifies missense variations C573F, and T58A as high-risk deleterious SNPs 2024 Journal of Biomolecular Structure and Dynamics, Volume 42, Year 2024, Pages 4072-4086

   3. G Siva Sankari, R James, F Payva, V Sivaramakrishnan, Computational analysis of sodium-dependent phosphate transporter SLC20A1/PiT1 gene identifies missense variations C573F, and T58A as high-risk deleterious SNPs. Journal of Biomolecular Structure and Dynamics 42 (8), 4072-4086

   4. Gunavathi V.;Santhy K.S. In silico studies of natural compounds of Lannea coromandelica as Wound healing and Anti-inflammatory agents 2024 Research Journal of Biotechnology, Volume 19, Year 2024, Pages 40-50   DOI:10.25303/1902rjbt040050     

   5. Unni R.K.;Pavithra A.E.;Kumar A.G.;Santhy K.S. Exploring the Impact of Resveratrol on Gynecological Cancer: Insights and Perspectives. Plant Science Today, Volume 10, Year 2023, Pages 203-211        DOI: https://doi.org/10.14719/pst.2549  

   6. E Deepika, KS Santhy. Unravelling the Mode of Action of Wound Healing Efficiency with the compounds Screened from Hygrophila auriculata by Molecular docking Studies. Journal of Plant Science Research         DOI:10.32381/JPSR.2023.39.02.7  

   7. D Ekambaram, KS Santhy Phytochemical characterization and assessment of hygrophila auriculata (buch.-ham) leaves for antioxidant and antimicrobial activity. Indian Journal of Pharmaceutical Sciences 85 (2), 501-510        DOI: 10.36468/pharmaceutical-sciences.1116

   8. N Rangasamy, KS Santhy. Identification of Differentially Expressed Genes and Key Pathways Associated with PTPN11 Mutation in Acute Myeloid Leukemia. Journal of Scientific Research 66 (3)  DOI: 10.37398/JSR.2022.660313

   9. Deepika E,  and Santhy K.S., 2022. In vitro Antioxidant and Antidiabetic activity of Silver Nanoparticles Synthesized using Catharanthus roseus leaves. International Journal of Food and Nutritional Sciences; Volum 15:3  DOI: 10.52711/0974-360X.2022.00165.

   10. Shebriya Abdulla, Amrisa Pavithra E & Santhy K S., 2022. Effect of Semecarpus anacardium L.f. ethanol extract on serum biochemical parameters and antioxidant activity of DAL induced mice. Plant Science Today vol 9(3):658-663. https://doi.org/10.14719/pst.1522.

   11. Shebriya Abdulla, Santhy K.S., 2022.Enzymic and Non-Enzymic Antioxidant Activity of Semecarpus anacardium (Linn.) Nut. Int J Food Nutr Sci; 11: 27-30. 5_IJFANS_51_21_27-30.  5_IJFANS_51_21_27-30. 5_IJFANS_51_21_27-30.

   12. Rangasamy N.;Arulraj P.;Santhy K.S.  Computational identification of co-expression networks, key genes and pathways in acute myeloid leukemia. Article Applied Biological Research, Volume 24, Year 2022, Pages 280-287   DOI: https://doi.org/10.48165/

   13. Shebriya Abdulla and K. S. Santhy  2021 Evaluation of Antitumor Properties of Semecarpus anacardium Nuts using Daltons Ascites Lymphoma Bearing Swiss Albino Mice, 12 (05): 1815–1818. http://rjas.org

https://www.researchgate.net/publication/363022470_Evaluation_of_Antitumor_Properties_of_Semecarpus_anacardium_Nuts_using_Daltons_Ascites_Lymphoma_Bearing_Swiss_Albino_Mice

1. 14. S GAYATHRI, KS Santhy. Wound Healing Activity of Heliotropium indicum L. leaf extract. SGS-Engineering & Sciences 1 (01)

   15. KS Santhy. Anti-cancer efficacy of Cocos nucifera sprouts against Acute myeloid leukemia associated protein-PTPN11. SGS-Engineering & Sciences 1 (01)

   16. Nithya Rangasamy, N. S. Kumar, K. Santhy 2021 Computational analysis of missense variants in MMP2 gene linked with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis reveals structural shift in protein-protein and protein-ligand complexes, Meta Gene;Vol 29. DOI:10.1016/J.MGENE.2021.100931.

   17. Jayaramayya, Kaavya and Santhy, KS. Life Style Factors Associated With Ampullary Carcinom. NVEO-NATURAL VOLATILES \& ESSENTIAL OILS Journal| NVEO, Volume , Year 2021, Pages 11442—11449

   18. Valsala, P., Deepika, E. and Santhy, K.S. 2021 Phytochemical Screening and Free Radical Scavenging Potential of Mentha piperita L, The Indian Journal of Nutrition and Dietetics; 1:73-80. https://www.researchgate.net/profile

   19. Valsala, P.,Deepika, E., Santhy, K.S., 2021.Enzymatic and Non enzymatic anti-oxidant activities of Methanol extract of Mentha piperita L. Journal of Advanced Scientific Research,12(1): 140-144.

   20. Zeenath V. M. H.*, Deepika E. , Santhy K. S.Comparative Phytochemical Analysis and Free Radical Scavenging Activity of Different Extracts of Allium ascalonicum (Shallots), The Indian Journal of Nutrition and Dietetics;Volume 58, Issue S2, 2021.  https://doi.org/10.21048/IJND.2021.58.S2.28007.

   21. Zeenath Vadakkenchery Mohammed Hussain, Santhy Kumaran Sivanandhan* 2021 Antiproliferative and Apoptotic Induction of Allicin in Human Lung Cancer Cell Lines, Indian Journal of Pharmaceutical Education and Research; 55(2): 566-573. https://www.ijper.org/sites/default/files/IndJPhaEdRes-55-2-566.

   22. Lekha, G.S., Deepika, E., Swetha, S., Kanagarajan, A., Gayathridevi, V. and Santhy, K.S. 2020. In vivo evaluation of antimicrobial, antipyretic, analgesic, and anti-inflammatory activities of Nilavembu Kudineer capsule in comparison with siddha classical Nilavembu Kudineer. Pharmacognosy Research, 12(4): 387-393. https://www.phcogres.com/article.asp?issn=0974-490;year=2020;volume=12;issue=4;spage=387;epage=393;aulast=Lekha

   23. Santhy, K.S., Krishnaveni, N., Hajara Banu. T.M.,2020. In silico docking studies to screen the potent antidiabetic compound from leaves of Azadirachta indica., Research highlights, 30(3): 159 - 165.

   24. Jayaramayya, K.,Iyer, M.and Kumaran, S.S., 2020. Mitochondrial gene mutations in Ampullary Carcinoma. World journal of pharmacy and pharmaceutical sciences. 9(6):958-966 https://www.wjpps.com/Wjpps_controller/abstract_id/12431

   25. Mahalaxmi, I., Devi, S.M., Kaavya, J., Arul, N., Balachandar, V. and Santhy, K.S., 2019. New insight into NANOG: A novel therapeutic target for ovarian cancer (OC). European journal of pharmacology, 852:51-57. IF- 3.170  https://www.sciencedirect.com/science/article/abs/pii/S0014299919301529

   26. Kaavya, J., Mahalaxmi, I., Devi, S.M., Santhy, K.S. and Balachandar, V., 2019. Targeting phosphoinositide‐3‐kinase pathway in biliary tract cancers: A remedial route?. Journal of cellular physiology, 234(6): 8259-8273. IF - 5.546 https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.27673

   27. Iyer, M., Jayaramayya, K., Bupesh, G. and Kumaran, S.S., 2019. Identification of mitochondrial DNA profiling (COX-2) in ovarian cancer patients-A population-based study in South India. International Journal of Research and Development in Pharmacy & Life Sciences, 8(1) :25-28. https://www.ijrdpl.com/index.php/ijrdpl/article/view/55

   28. Iyer Mahalaxmia, Jayaramayya Kaavyaa, G. Bupeshb, Kumaran Sivanandan Santhy 2018  Assessment Of Chromosomal Alterations And Gene Mutations In Cldn3 In Ovarian Cancer Patients From South Indian Population, World journal of  pharmacy and pharmaceutical sciences; 8(6), 1441-1449. https://www.wjpps.com/Wjpps_controller/abstract_id/10760

   29. Sivanandan, S. and Pimple, S., 2018. Molecular Docking Studies of Alpinia galanga Phytoconstituents for Psychostimulant Activity. Advances in Biological Chemistry, 8(4): 69-80. https://www.scirp.org/journal/paperinformation.aspx?paperid=86091

   30. I Mahalaxmi, KS Santhy Role and hallmarks of Sp1 in promoting ovarian cancer. Journal of oncological sciences 4 (2), 102-105

   31. RK Upadhyay. Plant pigments as dietary anticancer agents. International Journal of Green Pharmacy (IJGP) 12 (01)

   32. Dhivya, J.V. and Santhy, K.S., 2018. Demystifying the ethnomedicinal plant Morinda pubescens with ethnopharmacological, phytochemical, and pharmacotoxicological evidence. Journal of Critical Reviews, 5(5):1-6.  http://www.jcreview.com/fulltext/197-1572332779.pdf

   33. Mitochondrial DNA D-Loop mutation in malignancy. Review Research Journal of Biotechnology, Volume 13, Year 2018, Pages 100-108

   34. Jayaramayya Kaavya, Vellingiri Balachandar, Kumaran Sivanandan Santhy 2018 Ampullary Carcinoma – A Genetic Perspective, Mutation Research/Reviews in Mutation Research; 776: 10-22. https://doi.org/10.1016/j.mrrev.2018.03.002 

   35. Meena, J., Archana, D. and Santhy, K.S., 2018. In silico analysis of Cyclea peltata (Lam.) Hook. f. & Thomson root extract for docking studies of the compound β‑estradiol. Indian Journal of traditional knowledge 17(1):162-167. c

   36. Saranya, S., Archana, D., Saranya, S., Archana, D. and Santhy, K.S., 2017. Antimicrobial and antioxidant effects of Nerium oleander flower extracts. International Journal of Current Microbiology and Applied Sciences, 6(5):1630-1637. https://www.ijcmas.com/6-5-2017/S.%20Saranya,%20et%20al.pdf

   37. Mahalaxmi, I. and Santhy, K.S., 2017. An overview about mitochondrial DNA mutations in ovarian cancer. Alexandria Journal of Medicine, 53(4):307-310. https://www.ajol.info/index.php/bafm/article/view/163720

   38. Sreejaya, S.B., Archana, D. and Santhy, K.S., 2017. Biochemical changes in the serum of experimental animals treated with Acorus calamus rhizome. Studies on Ethno-Medicine, 11(3):216-220. https://www.tandfonline.com/doi/abs/10.1080/09735070.2017.1353109  IF- 0.349

   39. Vellingiri Balachandar, Venkatesan Dhivya, Mariappan Sujitha, Balasubramanian Venkatesh, Kumaran Sivanandan Santhy, Siva Kamalakannan. Association of the shank3 gene coupled with 22q13. 3 deletion syndrome. International Journal of Research and Development in Pharmacy & Life Sciences.Volume 5,Issue 6 Pages, 2369-2387

   40. Santhy, K.S., Meena. J., 2015. Anticancer efficacy of Cyclea peltata on human breast carcinoma cells. Indian drugs., 54 (6): 53-57. https://www.researchgate.net/publication/318584199_Anticancer_efficacy_of_Cyclea_peltata_on_human_breast_carcinoma_cells

   41. Sreejaya,S.B., Archana,D. and Santhy, K.S., 2017. Genoprotective effects of Acorus calamus rhizome against DNA damage in peripheral blood lymphocytes. International Journal of Green Pharmacy (IJGP), 11(1):108-111. http://www.greenpharmacy.info/index.php/ijgp/article/view/880

   42. Archana, D. and Santhy, K.S.,2017. Galangal phytocompounds in tumour tactics - an in silico Analysis targeting breast cancer. International Journal of Pharma and Bio sciences. 8(3):411-420. https://ijpbs.net/abstract.php?article=NjAzMw==

   43. Laleethambika, N., Dharwadkar, M.N., Santhy, K.S., Sangeetha, M., Silambuchelvi, D. and Balachandar, V., 2016. Evaluation of M2/ANXA5 haplotype and P53 codon 72 polymorphism in a patient with recurrent pregnancy loss, ectopic pregnancy and recurrent implantation failure. International Journal of Human Genetics, 16(3-4), pp.166-171. IF- 0.36 https://www.tandfonline.com/doi/abs/10.1080/09723757.2016.11886294

   44. Anand, L., Padmavathi, V., Venkatesh, B., Santhy, K.S., Sangeetha, M., Sasikala, K. and Balachandar, V., 2016. Population Screening of K-ras Gene and Genetic Counselling for Patients Affected with Ampulla of Vater in Tamil Nadu. International Journal of Human Genetics, 16(3-4):141-147. IF- 0.36 https://www.tandfonline.com/doi/abs/10.1080/09723757.2016.11886291

   45. Meena, J. and Santhy, K.S., 2015. Evaluation of the antioxidant potential of methanol extract of Cyclea peltata in DAL Model. The Pharma Innovation, 4(1):71-75

   46. Srividya, M. and Santhy, K.S., 2015. In vitro study on anticancer activity of pomegranate fruit extract in lymphocytes of breast cancer patients. Journal of Pharmacy Research, 9(4):50-254.

   47. Sreejaya, S.B. and Santhy, K.S., 2015. Antineoplastic and antioxidant activities of Acorus calamus L.on swiss albino mice bearing Dalton’s ascites lymphoma. Asian J. Pharm. Clin. Res., 8(6):97-100.  https://innovareacademics.in/journals/index.php/ajpcr/article/view/7723

   48. Archana. D., Santhy. K.S., Nithya Devi. P., 2015.Assessment of anticancer activity of Solanum torvum L. nanoparticles., Res. High, JADU.25: 203-213.

   49. Dixitha M, Archana D, Santhy KS., 2015. Phytochemical and antimicrobial screening of methanolic extracts of Piper longum L. International Journal of Pharmacology Research.5(2):166-169

   50. Santhy K Sivanandan., 2015.Extended synthesis of storage proteins in silkworm, Bombyx mori in response to Juvenile Hormone Analogue(JHA) treatment. Int J Pharm; 5(4): 1126-1131 https://www.pharmascholars.com/articles/extended-synthesis-of-storage-proteins-in-silkworm-bombyx-mori-in-response-to-juvenile-hormone-analogue-jha-treatment.pdf

   51. Meena, J. and Santhy, K.S., 2015. Efficacy of methanolic extract of Cyclea peltata as a potent anticancer equivalent. Eur. J.Environment Ecol, 2: 65-71  https://www.arjournals.org/index.php/ijpm/article/view/1676

   52. Sreejaya, S.B. and Santhy, K.S., 2015. Drug Based Computational Analysis for Initial Stages Breast Cancer with Compounds Obtained from Acorus Calamus. International Journal of Pharmacognosy and Phytochemical Research, 7(6):1256-1261. http://impactfactor.org/PDF/IJPPR/7/IJPPR,Vol7,Issue6,Article36.pdf

   53. Archana, D., Dixitha, M. and Santhy, K.S., 2015. Antioxidant and anti clastogenic potential of Piper longum L. Int. J. Appl. Pharm., 7(2), pp.11-4. https://innovareacademics.in/journals/index.php/ijap/article/view/8471

   54. Santhy, K.S., 2015. Rates of Feeding and Assimilation in the Silkworm Bombyx mori L.as Influenced by Methoprene. Journal of Applied Pharmaceutical Science, 5(10):101-106. http://japsonline.com/admin/php/uploads/1659_pdf.pdf

   55. Karthika,G., Archana,D. and K. S. Santhy., 2015. Antioxidant and cytotoxic effects of methanol extracts of Amorphophallus paeoniifolius Ni. Asian Journal of Pharmaceutical and Clinical Research, 8(6): 106-9, https://innovareacademics.in/journals/index.php/ajpcr/article/view/7739.

   56. Das, A. and Santhy, K.S., 2015. Free Radical and Antioxidant Properties of Alpinia Galanga (L.) Willd. Int. J .Pharm. Bio. Sci., 6(4):378-385.

   57. Das, A. and Santhy, K.S., 2015. Chemical Characterisation of Alpinia galanga (L.) Willd by Gc–Ms, XRD, FTIR and Uv-Vis Spectroscopic Methods. International Journal of Pharmacy and Pharmaceutical Sciences, 7(9):499-501 https://innovareacademics.in/journals/index.php/ijpps/article/download/6547/pdf_1151

   58. Meena, J. and Anandan, S.., 2015. Antitumor activity of methanolic extract of Cyclea peltata. International Journal of Phytomedicine, 7(2), pp.185-192. https://www.cabdirect.org/globalhealth/abstract/20153325176

   59. Geetha, B. and Santhy, K.S., 2013. Sexual risk factors for cervical carcinogenesis-A case control study. Int. J. Curr. Microbiol.Appl. Sci., 2:.394-9. https://www.ijcmas.com/vol-2-8/B.Geetha%20and%20K.S.%20Santhy.pdf

   60. Geetha, B. and Santhy, K.S., 2013. Evaluation of anti tumour properties of methanol extract of green tea against Daltons ascites lymphoma cells. Int. J.Agric. Sci.&Vet. Med. 1(3):145-151

   61. K.S. Santhy and S. Sarojini . Juvenoid induced effects on the growth and differentiation of gonads in the silk worm, bombyx mori l. 2013. Ecology, Environment and Conservation Paper. Volume 19 Pages 989-993.

   62. Santhy, K.S. and Geetha, B., 2013. Antimutagenic effect of green tea extracts in reverse mutation assay. Int. J. Pharm. Med. and Bio. Sci, 2(1):62-67 http://new.ijpmbs.com/ijpmbsadmin/upload/ijpmbs_50e519d44f1a5.pdf

   63. Santhy.K.S., Sarojini.S.,2013. Juvenoid induced effects on the growth and differentiation of gonads in the silk worm, Bombyxmori L. Eco. Env. & Cons.19(4):989-993. https://www.researchgate.net/publication/281739525_Juvenoid_induced_effects_on_the_growth_and_differentiation_of_gonads_in_the_silk_worm_Bombyx_Mori_L

   64. Santhy,K.S., Srividya, M. and Arulraj, P., 2012. Reproductive factors and risk of breast cancer among women in Tamilnadu, India. Asian Journal of Research in Social Sciences and Humanities, 2(3):14-27. https://indianjournals.com/ijor.aspx?target=ijor:ajrssh&volume=2&issue=3&article=002

   65. Santhy, K.S. and Vijayalakshmi,A. 2012.Water quality of river and reverine ground water along Bhavani basin, Res. High. JADU, 22:211-216

   66. Cho, Y.E., Alcantara, E., Kumaran, S., Son, K.H., Sohn, H.Y., Lee, J.H., Choi, C.S., Ha, T.Y. and Kwun, I.S., 2010. Red yeast rice stimulates osteoblast proliferation and increases alkaline phosphatase activity in MC3T3-E1 cells. Nutrition Research, 30(7):501-510. IF -2.281  https://www.sciencedirect.com/science/article/abs/pii/S0271531710001168

   67. Santhy, K.S., Anupama, K.S., Srividya, M., Mangayarkarasi, K.S., Arulraj, P. and Usharani, M.V., 2009. Assessment of Tumour Response to Multimodalities of Treatment in Locally Advanced Breast Cancer Patients Using Comet Assay. International Journal of Human Genetics, 9(3-4):251-254. IF- 0.36 https://www.tandfonline.com/doi/abs/10.1080/09723757.2009.11886075

   68. Santhy,K.S. and Srividya,M. 2009. Antimutagenic effect of Pomegranate fruit extract in reverse mutation assay. Plant Archives, 9(2):563-566. IF- 0.07

   69. Santhy, K.S., Sherly, P.G. and Arulraj, P., 2007. Antimutagenic activity of Pomegranate (Punica granatum) in the Salmonella typhimurium reverse mutation assay. Asian Journal of Microbiology, Biotechnology and Environmental Sciences, 9(2):255-258 https://www.researchgate.net/publication/288666305_Antimutagenic_activity_of_pomegranate_punica_granatum_in_the_salmonella_typhimurium_reverse_mutation_assay

   70. Santhy, K.S. and Sukumar, S., 2007. Effect of agro-industrial wastes on the soil characteristics and nutritional status of Mulberry plants. Journal of Ecobiology 20(2):149-152

   71. Krishnaveni, N.,Santhy, K.S., and A S Devanesan., 2007. Beneficial effect of Amaranthus caudatus grown in the vermicompost for the treatment of stomatitis. Res. High, JADU.17:30-34

   72. Santhy, K.S., Krishnaveni, N. and Thamarai Selvi, G., 2006. Evaluation of Physico-chemical properties of river and riverine ground water along Pykara basin. Res. High, JADU.16:142-147

   73. Sivakumar, S and Ravi, V and Subburam, V and others. The effects of coirpith compost on the growth and quality of leaves of the mulberry plant Morus alba L. Bioresource technology, Volume 72, Year 2000, Pages 95—97

   74. Sivaselvi, R., Santhy, K.S., Sukumar, S. and Arulraj, P., 2005. Screening and evaluation of mutagenicity of Salmonella typhimurium in the river and well water samples. Journal of Ecotoxicology & Environmental Monitoring, 15(1):79-84.

   75. Santhy, K.S. and Sukumar, S., 1998. Studies on the effect of juvenile hormone analogue altosid on silkworm Bombyx mori L to improve silk yield. Res. High, JADU.8(3):31-36

   76. Santhy,K.S., Rita,J. and Vijayalakshmi, A. 1997.Recycling of coir pith to promote   the growth of   mulberry plants., Pro. Acad. Environ. Biol.,6(2):159-162

   77. Joseph, R., Vijayalakshmi, A. and Santhy, K.S., 1996. Efficient utilisation of coir wastes to improve the growth and yield of mulberry crop. Environmental Education and Information, 15:231-236.

   78. Santhy, K.S. and Sukumar, S., 1995. Impact of Foliar Spray of Selected Nutrients on the Economic Characters of Silkworm, Bombyx mori L.(Lepidoptera: Bombycidae). Environmental Education and Information 14:145-145.

   79. Santhy,K.S. and Sarojini Sukumar ,1994..Effect of foliar spray  of  micronutrients on  the larval development and cocoon characters of silkworm, Bombyx mori L.Res. High. JADU

   80. Sreejaya, S.B. and Santhy, K.S., 2014. Evaluation of antitumor properties of rhizome of Acorus calamus using Dalton’s ascites lymphoma bearing swiss albino mice. Int. J. Pharm. Bio. Sci., 5(4):119-125.

   81. S.B. Sreejaya and K.S. Santhy 2013 Cytotoxic properties of Acorus calamus in MCF-7 breast cancer cells. International of current research and academic review. Vol-1, Num1; (2013) pp. 106-111. http://www.ijcrar.com/vol-/S.B.%20Sreejaya%20and%20K.S.%20Santhy.pdf 

   82. Geetha, B. and Santhy, K.S., 2013. Anti-proliferative activity of green tea extract in human cervical cancer cells (HeLa). Int. J. Curr.Microbiol. Appl. Sci., 2:341-6. https://www.ijcmas.com/vol-2-9/B.Geetha%20and%20K.%20S.%20Santhy.pdf

   83. Geetha, B. and Santhy, K.S., 2013.  Tumour reducing and anticarcinogenic activity of Green tea againt Dalton's ascites Lymphoma cells. Int. J.Pharma. Med. Bio Sci.,2(3):92-96. https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.640.8530&rep=rep1&type=pdf

   84. Geetha, B. and Santhy, K.S., 2013. Evaluation of antimutagenic activity of orange peel extract using Ames Salmonella microsome assay. Int. J. Life Sc. Bt & Pharm. Res, 2:466-471. http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.644.3374&rep=rep1&type=pdf

Conference Publications :11

1. Valsala,P. and Santhy,K.S. 2019. Extraction and decisive action of alpha terpineol and its potential activity against human pathogenic microbes. Bonfring Publishers,ISSN 978939,DST- CURIE sponsored one day National Seminar on    “Biology For Life 2K19” , Department of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, pp.126-131

2. Deepika,E., Shanmugapriya,S. and Santhy,K.S. 2019.Phytochemical profiling and Invitro free radical scavenging Assay activities of Mussaendsfroudosa L. leaf extract. Bonfring Publishers,ISSN 9.78939, DST- CURIE sponsored one day National Seminar on    “Biology For Life 2K19” , Department of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore,pp.17-20.

3.   Angom Pushparani,D and Santhy,K.S.2008. Assessment of tumor response to multimodalities of treatment in bladder cancer patients using Comet assay.,Seminar cum exhibition on student project.,2007-2008 ,Tamil Nadu state council for science and technology, Chennai.

4. Anupama,K.S. Santhy,K.S., Mangayarkarasi,K.S. Usharani,M.V. 2007.Extent of DNA damage in the blood lymphocytes of Breast cancer, Proceedings of the International Conference on Biomarkers in Health and Environmental Management.,2007,PSG College of  Arts and  Sciences, Coimbatore.

5.  Santhy,K.S. Malarvizhi,V. and Sarojini,S. 2006.Status of Indian women in sericulture - An overview, Impact of globalisation on women with special reference to food security,2006,Avinashiligam University,pp.91-97

6. Evaluation of antimutagenicity of Pomegranate using Ames salmonella microsome assay, Proceedings of the regional seminar  on Medicinal Plants - A boon to the community,2006,Avinashilingam University.

7. Vijayalaksmi,M., Sherly,P.G., Santhy,K.S. and Sarojini,S.2004. Impact of supplementation of spirulina on silkworm, Bombyxmori L. (Lepidoptera: Bombycidae),Seminar on sericulture technology transfer to farmers of SC/ST population,2004, Kongunadu Arts and Science College, Coimbatore,pp.95-100

8. Sheeba,P.K. Kanimozhi,N. Santhy,K.S. and Sarojini,S. 2004Effect of amino acid supplementation in silkworm, Bombyx mori L. with reference to economic characters,Seminar on sericulture technology transfer to farmers of SC/ST population,2004, Kongunadu Arts and Science College, Coimbatore.pp.89-94

9. Srividya,M. and  Santhy,K.S.2003.Monitoring mutagens on  water samples in Salmonalla microsome assay in the presence of S9 fraction at Noyyal river belt,Seminar cum exhibition on student projects,2002-2003, Tamil Nadu state council for science and technology, Chennai,pp.331-332

10. Sivaselvi,R. and Santhy,K.S.Screening and evaluation of mutagenicity in the chosen samples of Noyyal river belt., Seminar cum exhibition on student projects,2001-2002,Tamil Nadu state council for science and technology, Chennai.

11. Sarojini Sukumar and Santhy,K.S. 1998.Pattupochivalarpil Altosid ennum ilamnilai seyarkai harmonai payan paduthi pattuurpathiyai perukkuthal., ThamilakaAriviyalperavai. Aram karuthuarangam,1998,pp.14-16

Official website -www.avinuty.ac.in/  

ORCID          -  0000-000207362-1962   

ResearcherID    -  AAX-3163-2020

Scopus           -  18042828800 

Google Scholar -  https://scholar.google.com/citations?user=ol6nJ6UAAAAJ

Seminar/ Conferences organised

1. One day Seminar on”Entrepreneurial opportunities in Sericulture” on 14.02.2020

2. One- day DST- CURIE Sponsored National Seminar on“BIOLOGY FOR LIFE 2K19"  on 11.12.2019

3. Workshop on "Scientific data analysis & Graphing using software" sponsored by Origin software, Bangalore  on 30.06.2017

4. Workshop on"Virtual Animal Dissections" sponsored by E-mantra interactive Technologies, Chennai on 21.03 2017

Coordinator

5. Two day DST-CURIE sponsored National Conference on Medicinal Plant research and Translational Trends (MPRTT 2017) on  18.12.2017  and  19.12.2017

   Invited lectures delivered / Papers presented in Conferences / Seminars: 35

1. Invited talk on "Insilico methods- A boon to anticancer reseach" in the webinar organised by the  Department of Zoology, SD College, Alapuzha, Kerala on 25.09.2020

2. Invited talk on ‘Molecular docking studies: A paradigm shift in anticancer research’  in the webinar organised by the Dept. of Zoology, Morning Star Home Science College,Angamaly,Ernakulam,Kerala on 16.5.2020

3. "Anticancer potential of Alpinia galangal L. Wild against breast cancer- An in silicoaproach". International conference on Herbal and natural components as the future pharmacology held from 27.02.2017 to 01.03.2017 at Avinashilingam University, Coimbatore.

4. "Effect of Methanolic Extract of Acorus calamus Rhizome on serum enzyme levels in experimental animals". UGC Sponsored National seminar on Emerging Trends in Phytopharmaceuticals held from 13.01.2016 to 14.01.2016 organised by Department of Botany, Vimala College, Thrissur, Kerala.

5. "Protective effect of methanolic Extract of Acorus calamus against DNA damage in peripheral blood lymphocytes". International Conference on Translational Cancer Research (ICTCR-2015) held from 14.12.2015 to 16.2.2015 at  Avinashilingam University,Coimbatore

6. Invited lecture on "Recent trends in cancer research"on 28.10.2015 at Department of Zoology, GVG. Visalakshi College for Women, Udumalpet.

7. "Evaluation of antioxidant status of Cyclea peltata on Dalton's  Lymphoma Ascites induced mice". International conference on Reasserting Microbial Biotechnology to Deflate Global Disease Burden - RMBT’ held 15. 28.09.2015 to  29.09.2015 at  ManonmaniamSundaranar University,Tirunelveli

8. "Screening of antitumor properties of Acorus calamus L. using Dalton’s Ascites Lymphoma bearing mice". International conference on “Medicinal Plants and Herbal Drugs for Human Welfare (ICMP-2015) held 28.01.2015 to 30.01.2015 at University of Madras

9. Evaluation of tumour response to multimodalities of treatment in breast cancer patients using single cell gel electrophoresis. Breast Oncology-International Conference on Multidisciplinary Management of Breast Cancer held from 6.3.2014  to 8.3.2014 at  Cancer research and treatment society and breast cancer foundation of India,Kochi

10. "Antioxidant status of methanol extract of Acorus calamus against Daltons lymphoma ascites induced tumor in mice". Computational Biology and Drug Design held from  10.07.2013 to 12.07.2013 at  School of Biosciences, MACFAST, Tiruvalla, Kerala.

11. "Anticancer activity of green tea extract in the lymphocytes of cervical cancer patients". Conservation strategies for Bio resources held from  05.02.2013 to 06.02. 2013 at PSGR Krishnammal College for Women,Coimbatore

12. "Antigenotoxic activity of Pomegranate Fruit Extract in lymphocytes of Breast cancer patients in vitro" . International conference on Global competitiveness in Biology, Chemistry and Environment: For better tomorrow-Proteo fest 2011 on  03.02.2011 at  the Dept.of Biochemistry, Rev.Jacob Memorial Christian College, Ambilikkai, Tamilnadu

13. "Evaluation of antigenotoxic potential of pomegranate in the peripheral blood lymphocytes of breast cancer patients". Holistic maternal and child care nutrition. held on 22.09.2011 organised by  Nestle nutrition institute &Avinashilingam University

14.  Invited talk on "Recent trends in Cancer research". Summer training programme in Biological Sciences for Postgraduate students held on 25.05.2011at  Avinashilingam University.

15. Invited talk on "Recent trends in Cancer Research" in  Darsan 2010 held on 12.10.2010 at T. K. Madhava Memorial College, Nangiarkulangara, Kerala. 

16. Invited talk on"  Prospects of Cancer research " in the inauguration of Zoology Association on 29.07.2009 at Nirmala College for Women, Coimbatore.

17.  Invited talk on Threats to biodiversity and methods of conservation". Gandhian Perspective of Environmental Management on  12.01.2009 at  Avinashilingam Deemed University.

18. "Diosgenin stimulates proliferation, Collagen level and ALP activity in osteoblastic MC3T3 –E1 cells". Food for Health and Longevity-2009- International Symposium and Annual meeting from  04.11.2009  to 06.11.2009. The Korean Society of Food Science and Nutrition, Changwon, Korea .

19. "Study of different comet parameters in blood lymphocytes of breast cancer patients", Seminar on current trends in advanced biological research, CTAB – 2007, 01.02. 2007 to 02.02. 2007, Department of Biotechnology, Nehru Arts and Science College, Coimbatore

20. "Antimutagenic effect of tea (Camellia sinensis) in Salmonella typhimurium TA 98 and TA 100 strains". National conference-Womenscientists/technocrats opportunities and challenges, DST, CSIR, Kerala State Women Development Corporation organised by  Shakti-Women’s wing of VijnanaBharati,Kochi

21. "Anti mutagenic effect of  green and black tea in Salmonella typhimurium TA98 and TA100 strains". Seminar on Medicinal Plants - A boon to the community on  17.02.2006 at  Avinashilingam University, Coimbatore.

22. "Evaluation of antimutagenicity of Pomegranate using Ames salmonella microsome assay". Seminar on Medicinal Plants - A boon to the community on 17.02.2006 at Avinashilingam University, Coimbatore. 

23. "Impact of supplementation of spirulina on silkworm, Bombyxmori L. (Lepidoptera: Bombycidae)". Seminar on Sericulture technology transfer to farmers of SC & ST population held from  29.9.2004 to 30.9.2004 at  PG & Research Department of Zoology, Kongunadu Arts and Science College.

24. "Rates of feeding and assimilation in the silkworm , Bombyxmori as influenced by Methoprene". National symposium on recent trends in applied biology held from  28.1.2004 to 29.1.2004 at  Avinashilingam Deemed University.

25. "Extended synthesis of storage proteins in silkworm Bombyxmori in response to Juvenile Hormone Analogue  (JHA)treatment". National symposium on recent trends in applied biology held from   28.1.2004 to 29.1.2004 at  Avinashilingam Deemed University.

26. "Assessment of mutagenicity in the river and well water samples from Noyyal  River Basin". National seminar on Current Trends in Biological Sciences held from 12.12.2002 to 13.12.2002 at Avinashilingam University, Coimbatore.

27. "Leaf  extracts as biopesticides against the filarial vector Culex quinquefasciatus". National symposium on recent trends in restoration of aquatic environment and biodiversity of insects held on 16.12.2002 at  PG &Research Department of Zoology, Kongunadu Arts and Science college, Coimbatore.

28. Invited lecture on "Sericulture  and its prospects in rural economy". UGC refresher course for University / College teachers held on 26.09.2000 at Avinashilingam Deemed University.

29. "Modulatory effect of Methoprene on the storage protein profile of Silkworm, Bombyxmori L". Entomocongress - 2000 - International conference on Perspectives for the new millenium  held from 5.11.2000 to 8.11.2000 organised by  Dept. of  Zoology, University of Kerala, Trivandrum

30. "Impact of Manta (Methoprene) on the storage of silkworm Bombyxmori L." 12th National symposium on Reproductive Biology and Comparative Endocrinology held from  21.1.1998 to 23.1.1998 at  University of Kerala, Trivandrum

31. "Influence of juvenile hormone analogue, Fenoxycarb on the protein profile of Helicoverpaarmigera H." 17th annual session of the Academy of Environmental Biology held from  16.11.1996 to 18.11.1996at  M.D. University, Haryana.

32. "Effect of a few agro-industrial wastes on the soil characteristics and the nutritional status of mulberry plants". 16th Annual Session of the Academy of Environmental Biology-Academy of Environmental Biology held from  23.11.1995 to 25.11.1995 at  Andrapradesh Agricultural University, Hyderabad.

33. "Recycling of coir pith to promote the growth of mulberry plants". 15th Annual Session of the Academy of Environmental Biology held from  7.11.1994  to 9.11.1994 at  Kerala Agriculture University, Trivandrum.

34. "Effect of Juvenile hormone analogue, methoprene on the chosen characters of silkworm, Bombyx mori L." 12th National symposium on Reproductive Biology and Comparative Endocrinology held from  21.1.1994  to 23.1.1994 at  Pondicherry University, Pondicherry.

35. "Effect of foliar spray of N, Fe and Zn on the reproductive potential ,larval and cocoon characters of silk worm Bombyx mori L. 11th National symposium on Reproductive Biology and comparative Endocrinology held from  29.1.1993 to 30.1.1993 at S. V. University, Thirupathi".

AWARDED

P.hD. : 6

M.Phil.: 5

Ph. D. Thesis completed

1. Srividya M. 2011.Assessment of antigenotoxic potential of Punica granatum in the reversal of DNA damage in breast cancer patient http://hdl.handle.net/10603/5567

2. Geetha B.2015. Epidemiology of cervical cancer and antigenotoxic activity of green tea on cervical cancer cell http://hdl.handle.net/10603/36870

3. Sreejaya,S.B.2016.Evalution of the anticancer properties of Acorus calamus Rhizomes using invitro, invivo and in silico models. http://hdl.handle.net/10603/74889

4.  Meena,J.2016.Pharmacogeneticevaluation of methanolic extract of Cyclea peltate (Lam) Hook.F.Thoms for its anticancer properties. http://hdl.handle.net/10603/208480

5. Archana Das.2017. Invitro antioxidant and antigenotoxic potential and Insilco molecular docking on alpinia galangal (L) wild http://hdl.handle.net/10603/141795

6. Iyer Mahalakshmi Anand Meera.2019.Genetic and epigenetic alterations in nuclear and mitochondrial genes in ovarian cancer patients.http://hdl.handle.net/10603/310822

M.Phil. Thesis completed

1. Sivaselvi,R. 2003.Genotoxic risk assessment of rever and ground water of Orathupalayam in Tamilnadu 

2. Anupama,2006.Assessment of tumour response to multimodalities of treatment in Locally Advanced Breast Cancer (LABC) patient using comet assay 

3. Geetha,B.2007.Evaluation of antimutagenic activity of lemon and orange-peel extracts using Ames salmonella microsome assay

4.  Dhivya,J.V. 2018.Anticancer effect of Morinda coreia Buch Ham. on the non- small lung cancer cell line 

5. Deepika,E. 2020.In vitro diabetic activity and in silico molecular docking of Nilavembu, Andrographis paniculata (Burm.f) Nees 

ONGOING

PhD. Thesis

1. Valsala,P. Pharmacognostic Evaluation of the Anticancer Properties of Mentha piperita L. Using in silico, in vitro and in vivo Models 

2. Zeenath, VMH. Exploration of Anticancer Properties of Allium ascalonicumL.using in silico, in vitro, and in vivo Lung CancerModels

3. Kaavya J.  Epigenetic regulation, Protein profiling, mitochondrial dysfunction and gene expressionstudies in Ampulla of Vater carcinoma

4. Shebriya Abdulla.  Pharmacognostic Evaluation of the Anticancer Properties of Semicarpus Anacardium using in silico, in vitro and in vivo Models 

5. Nithya P. Bioinformatic analysis of transcriptomic and proteomic data of Acute Myeloid Leukemia

6. Deepika,E. Antidiabetic potential of Hygrophila auriculata: Exploring mechanism for blood sugar control

7. Ramya James. A system biology aooroach to discover potential genetic markers for different types of Osteoporotic fractures

8. Febby Peyva.A system bilogy approach of Thyroid cancer

9. Gunavathi, V. Wound healing and anti-inflammatory activity of synthesized niosome in Lannea coronandelica leaves by using invitro, invivo and insilico studies.

10. Amrisa Pavithra, E. 

11. Aparna, G. Kumar. 

12. Revathi Unni, K.  System biological approach in Endometrioid Cancer.

• Member

• Member-Experts committee-Mentor, DBT Star College status,Nirmala College,Coimbatore -2016-2021

• Board of Studies, Avinashilingam institute for Home Science and Higher education for women,Coimbatore,Member

• Academic Council,Avinashilingam institute for Home Science and Higher education for women,Coimbatore,Member

• Board of Studies, Nirmala College,Coimbatore, Member

• Subject expert,Academic audit, Department of Zoology, Nirmala College

• Board of Studies, Kongunadu Arts and Science College,Coimatore, Member

• Swift, Forest college,Coimbatore, Sub Member

• Alumnae Association, Secretary,Faculty of Science,Avinashilingam University,Coimbatore,

• Red Ribbon club,Avinashilingam University, Nodal officer

• Red Ribbon club,Avinashilingam university, Programme officer

• National Service Scheme, Programme officer-2004-2008,2012-2016

• Professional certification course, 2016-18 Co-ordinator

• PG Internship-202-2021,Coordinator

• CBCS, Coir board, Govt of India, Cochin,2001

• Member,Question Paper setting Board,St. Mary’s College, Tutucorin,Holy Cross College,Nagercoil,

Bharathiar University,Coimbatore,Periyar University,Salem

• Life Membership

• Association for Advancement of Entomology,2000

• 3T Wildlife Association,2013

• National Society of Ethno pharmacology,2017

• Reviewer for Journals

• Journal of Medicinal Food. Korean Society of Food Science and Nutrition,ISSN No.1557-7600

• Nutrition Research and Practice,Korean Society of Food Science and Nutrition,ISSN No.1976-1457

• Open Pharmaceutical Sciences Journal,Bentham Open, ISSN No.1874-8449

• The Open Ecology Journal,Bentham Open,ISSn No.1874-2130

• Issues in Biological Sciences and Pharmaceutical Research,ISSN No. 2350-1588

• International Journal of Pharmacy and Pharmaceutical Sciences,I nnovare academics,ISSN No.0975-1491

• Entomon, Association for Advancement of Entomology, ISSN No.0377-9335

• Advances in Applied Research, PSGR Krishnammal college for Women,ISSN No.0974-3839