PUBLICATIONS


Google Scholar

2012

Choi, S. H., T. E. Wales, Y. Nam, D. O'Donovan, P. Sliz, J. R. Engen and S. C. Blacklow (2012). Conformational locking upon cooperative assembly of Notch transcription complexes. Structure 20(2): 340-349.

O'Donovan, D., I. Stokes-Rees, Y. Nam, S. C. Blacklow, A. T. Brunger and P. Sliz (2012). A grid-enabled web service for low-resolution crystal structure refinement. Acta Crystallogr D Biol Crystallogr 68(Pt 3): 261-267. 

2011

Nam, Y., Chen, C., Gregory, R.I., Chou, J.J., and Sliz, P (2011). Molecular basis for interaction of let-7 microRNAs with Lin28. Cell 147: 1080–1091. pdf

Lazarus, M. B.*, Y. Nam*, J. Jiang, P. Sliz and S. Walker (2011). Structure of human O-GlcNAc transferase and its complex with a peptide substrate. Nature 469(7331): 564-567. pdf

Aster, J. C., N. Bodnar, L. Xu, F. Karnell, J. M. Milholland, I. Maillard, G. Histen, Y. Nam, S. C. Blacklow and W. S. Pear (2011). Notch Ankyrin Repeat Domain Variation Influences Leukemogenesis and Myc Transactivation. PloS one 6(10): e25645. pdf

2008

Erlandson, K. J., S. B. M. Miller, Y. Nam, A. R. Osborne, J. Zimmer and T. A. Rapoport (2008). A role for the two-helix finger of the SecA ATPase in protein translocation. Nature 455(7215): 984-987. pdf

Zimmer, J., Y. Nam and T. A. Rapoport (2008). Structure of a complex of the ATPase SecA and the protein-translocation channel. Nature 455(7215): 936-943. pdf

2007

Nam, Y., P. Sliz, W. S. Pear, J. C. Aster and S. C. Blacklow (2007). Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription. Proc Nat Acad Sci 104(7): 2103-2108. pdf

2006

Chiang, M. Y., M. L. Xu, G. Histen, O. Shestova, M. Roy, Y. Nam, S. C. Blacklow, D. B. Sacks, W. S. Pear and J. C. Aster (2006). Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1. Molecular and Cellular Biology 26(16): 6261-6271. pdf

Nam, Y.*, P. Sliz*, L. Song, J. C. Aster and S. C. Blacklow (2006). Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Cell 124(5): 973-983. pdf

2003

Nam, Y., A. P. Weng, J. C. Aster and S. C. Blacklow (2003). Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex. The Journal of Biological Chemistry 278(23): 21232-21239.  pdf

Weng, A. P., Y. Nam, M. S. Wolfe, W. S. Pear, J. D. Griffin, S. C. Blacklow and J. C. Aster (2003). Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling. Molecular and Cellular Biology 23(2): 655-664. pdf

2002

Nam, Y., J. C. Aster and S. C. Blacklow (2002). Notch signaling as a therapeutic target. Current Opinion in Chemical Biology 6(4): 501-509. pdf