PUBLICATIONS

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Wang P, Doxtader KA, Nam Y.
Mol Cell. 2016 Jul 21;63(2):306-317. doi: 10.1016/j.molcel.2016.05.041. Epub 2016 Jun 30

HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing.
Liu H, Liang C, Kollipara RK, Matsui M, Ke X, Jeong BC, Wang Z, Yoo KS, Yadav GP, Kinch LN, Grishin NV, Nam Y, Corey DR, Kittler R, Liu Q.
Mol Cell. 2016 Jul 12. pii: S1097-2765(16)30272-6. doi: 10.1016/j.molcel.2016.06.014. [Epub ahead of print]

Data publication with the structural biology data grid supports live analysis.
Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Christopher Fromme J, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P.
Nat Commun. 2016 Mar 7;7:10882. doi: 10.1038/ncomms10882.

A grid-enabled web service for low-resolution crystal structure refinement.
O'Donovan DJ, Stokes-Rees I, Nam Y, Blacklow SC, Schröder GF, Brunger AT, Sliz P.
Acta Crystallogr D Biol Crystallogr. 2012 Mar;68(Pt 3):261-7. doi: 10.1107/S0907444912001163. Epub 2012 Feb 14.

Conformational locking upon cooperative assembly of notch transcription complexes.
Choi SH, Wales TE, Nam Y, O'Donovan DJ, Sliz P, Engen JR, Blacklow SC.
Structure. 2012 Feb 8;20(2):340-9. doi: 10.1016/j.str.2011.12.011.

Molecular basis for interaction of let-7 microRNAs with Lin28.
Nam Y, Chen C, Gregory RI, Chou JJ, Sliz P.
Cell. 2011 Nov 23;147(5):1080-91. doi: 10.1016/j.cell.2011.10.020. Epub 2011 Nov 10.

Structure of human O-GlcNAc transferase and its complex with a peptide substrate.
Lazarus MB, Nam Y, Jiang J, Sliz P, Walker S.
Nature. 2011 Jan 27;469(7331):564-7. doi: 10.1038/nature09638. Epub 2011 Jan 16.

Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation.
Aster JC, Bodnar N, Xu L, Karnell F, Milholland JM, Maillard I, Histen G, Nam Y, Blacklow SC, Pear WS.
PLoS One. 2011;6(10):e25645. doi: 10.1371/journal.pone.0025645. Epub 2011 Oct 13.

A role for the two-helix finger of the SecA ATPase in protein translocation.
Erlandson KJ, Miller SB, Nam Y, Osborne AR, Zimmer J, Rapoport TA.
Nature. 2008 Oct 16;455(7215):984-7. doi: 10.1038/nature07439.

Structure of a complex of the ATPase SecA and the protein-translocation channel.
Zimmer J, Nam Y, Rapoport TA.
Nature. 2008 Oct 16;455(7215):936-43. doi: 10.1038/nature07335.

Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription.
Nam Y, Sliz P, Pear WS, Aster JC, Blacklow SC.
Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2103-8. Epub 2007 Feb 6.

Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1.
Chiang MY, Xu ML, Histen G, Shestova O, Roy M, Nam Y, Blacklow SC, Sacks DB, Pear WS, Aster JC.
Mol Cell Biol. 2006 Aug;26(16):6261-71.

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
Nam Y, Sliz P, Song L, Aster JC, Blacklow SC.
Cell. 2006 Mar 10;124(5):973-83.

Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex.
Nam Y, Weng AP, Aster JC, Blacklow SC.
J Biol Chem. 2003 Jun 6;278(23):21232-9. Epub 2003 Mar 18.

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling.
Weng AP, Nam Y, Wolfe MS, Pear WS, Griffin JD, Blacklow SC, Aster JC.
Mol Cell Biol. 2003 Jan;23(2):655-64.

Notch signaling as a therapeutic target.
Nam Y, Aster JC, Blacklow SC.
Curr Opin Chem Biol. 2002 Aug;6(4):501-9. Review.