Seth S. Blair is Professor and Associate Chair of the Department of Zoology at the University of Wisconsin-Madison.  

Dr. Blair's laboratory studies developmental biology, using molecular and genetic techniques to examine how cell signaling and cell lineage control axis formation, tissue patterning, cell polarity and organ growth.  The Blair Lab has concentrated largely on the model systems provided by the fruitfly Drosophila melanogaster, and especially the simple ectodermal and neuronal tissues of the developing wing.  Dr. Blair also worked on segmentation, cell lineage and cell interactions in annelid worms when he was a graduate student and postdoc in the Stent and Shankland labs

The Blair Lab trains graduate students from the Department of Zoology, the Genetics Training Program, the Cell and Molecular Biology Training Program, and the Neuroscience Training Program.  The Lab also trains postdoctoral fellows, and 1-3 undergraduates per semester either via the Independent Project portion of Biology 152 or through 699 research classes.

Dr. Blair's research is currently funded by the National Institutes for Health, with past additional support from the National Science Foundation.

Dr. Blair is Faculty Director of Introductory Biology 151/153-152, and teaches the cell biology and genetic portions of the course. He also teaches undergraduate courses in cellular neuroscience and neuronal development.  Dr. Blair was awarded the Chancellor's Award for Distinguished Teaching in 2013.

The latest publications:

Seth S. Blair (2017). Developmental compartments.  eLS 1-11. 

Hitoshi Matakatsu, Seth S. Blair and Richard G. Fehon (2017).  The palmitoyltransferase Approximated promotes growth via the Hippo pathway by palmitoylation of Fat. J Cell Biol. 216(1):265-277. doi: 10.1083/jcb.201609094. PMID: 28031421; PMCID: PMC5223609.

Yifei Zhang, Xing Wang, Hitoshi Matakatsu, Richard G. Fehon, and Seth S. Blair, S.S. (2016). The novel SH3 domain protein Dlish/CG10933 mediates fat signaling in Drosophila by binding and regulating Dachs. Elife Oct 3;5. pii: e16624. doi: 10.7554/eLife.16624. Erratum in: Elife. 2016 Nov 08;5:. PMID: 27692068; PMCID: PMC5047748.

Justin Schleede and Seth S. Blair (2015). The Gyc76C Receptor Guanylyl Cyclase and the Foraging cGMP-Dependent Kinase Regulate Extracellular Matrix Organization and BMP Signaling in the Developing Wing of Drosophila melanogaster
PLOS Genetics 10.1371/journal.pgen.1005576.  PMID: 26440503; PMCID: PMC4595086


Department of Zoology, University of Wisconsin  
250 North Mills Street, Madison WI 53706 USA
phone: 608-262-1345,  fax: 608-262-9083,  email: