TBI Model System Research Projects
Investigators at the TBI Model System have several projects currently, some of the currently approved are:
- Headaches after mild, moderate, and severe TBI
- Irritability and Aggression after TBI
- Social Interaction after TBI
- Sleep Disturbances after TBI
- Exercise after TBI
Look below for more details on specific projects:
Headaches after mild Traumatic Brain Injury
This study, also known as the APP Study, is investigating the efficacy of Amitriptyline in preventing post-traumatic headache in patients that have recently experienced a mild TBI.
This study has begun enrolling patients that have been admitted to Harborview Medical Center. At this time, patients must be admitted to Harborview Medical Center and also be within 2 weeks of their injury, in order to be eligible for the study.
Headaches after moderate to severe Traumatic Brain Injury
This study, also known as the TWIST Study, is investigating the efficacy of Sumatriptan in treating post-traumatic headache in people who have experienced a moderate to severe TBI in the last 3-12 months.
Sumatriptan has been approved for a very long time, and is effective in treating migraine headaches. This study is currently approved by the University of Washington's Human Subjects Division, but has not yet begun enrolling subjects.
Sleep Disturbances after moderate to severe TBI: Treatment with Light Therapy after TBI
This study, also known as the TWILIGHT Study, is investigating the efficacy of providing daily phototherapy in the morning to patients whom have experienced a recent TBI.
This study is currently recruiting patients whom are receiving care on the Inpatient Rehabilitation Unit at Harborview Medical Center.
Improving Social Competence after TBI
Other UW TBI Research
Funded by the NIH
Research Match aims to serve as an effective, useful and complementary recruitment tool that will help connect willing volunteers with researchers who are searching for appropriate volunteers to be placed in their research studies (not just clinical trials)