Our Research is Aimed at Elucidating the Mechanistic Details of Quality Control Pathways in Protein Synthesis and Decay.

We are particularly interested in investigating: 
  1. Molecular mechanisms that govern translational quality control
  2. Molecular basis for nonstop mRNA decay
  3. The mechanisms by which RNases and small non-coding RNAs (ncRNAs) regulate gene expression and RNA stability
  4. Biochemical mechanism of adaptor guided proteolysis and the role of AAA+ proteases in bacterial pathogenesis
  5. Discovery of novel antibiotics and vaccines.