Center for Anatomical Science and Education

Welcome to the Center for Anatomical Science and Education (CASE)! 

In these ever changing times of higher education, CASE is committed to:

  • providing innovative scholarship and effective teaching in all aspects of the structure of the human body
  • offering training programs in anatomy for graduate students 
  • assisting in M.D. and Ph.D. postdoctoral training
  • stimulating interest in research and technical expertise by active participation in a variety of research projects



  • Joshua W. Little D.C., Ph.D.  was recently awarded the inaugural Department of Kinesiology Distinguished Alumnus from Evangel University on 10/9/2014.
  • Joshua W. Little D.C., Ph.D. received the American Pain Society Young Investigator Travel Award to attend the 2014 33rd annual conference in Tampa, FL.. He will present his abstract entitled, "Central adenosine A3 receptor (A3AR) activation reverses neuropathic pain."

Graduate Student News

  • Dan Daly presented a paper entitled, "A neural mechanism for exacerbation of headache by light" by Noseda et al. 2010 on February 5, 2015 for CASE Journal Club.
  • John Merlo presented a paper entitled, "Rat Model of Lumbar Facet Joint Osteoarthritis Associated With Facet-mediated Mechanical Hyperalgesia Induced by Intra-articular Injection of Monosodium Iodoacetate" by Gong et al. 2011 on January 29, 2015 for CASE Journal Club.
  • Jessica McFarland presented a paper entitled, "Coronary CT angiography for the detection of coronary artery stenosis in patients referred for transcatheter aortic valve replacement" by Hamdan et al. 2015 on January 22, 2015 for CASE Journal Club.
  • Akiva Katz presented a paper entitled, "Increased Interleukin-1α and Prostaglandin E2 Expression in the Spinal Cord at 1 Day After Painful Facet Joint Injury " by Hamdan et al. 2015 on January 15, 2015 for CASE Journal Club.
  • Eric Brown successfully completed the M.S. (non-thesis) degree in Anatomy Friday December 12, 2014.  His project was entitled:  “A Foundational White Matter Atlas of Dissected Human Brain Specimens”

Recent Publications

  • Little J.W., Ford A., Symons-Liguori A.M., Chen Z., Janes K., Doyle T., Bannister K., Xie J., Tosh D.K., Dickenson A., Vanderah T.W., Porreca F., Jacobson K., and Salvemini D. Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. Brain. 2014. DOI: First published online: 20 November 2014. PMID: 25414036.
  • Janes K., Wahlman C., Little J.W., Doyle T., Tosh D.K., Jacobson K.A., and Salvemini D. Spinal neuroimmmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy. Brain, Behavior, and Immunity. 2014 Sep 8. pii: S0889-1591(14)00427-9
  • Janes K., Little J.W., Li C., Bryant L., Chen C., Chen Z., Kamocki K., Doyle T., Snider A., Esposito E., Cuzzocrea S., Bieberich E., Obeid L., Petrache I., Nicol G., Neumann W.L., and Salvemini D. The Development and Maintenance of Paclitaxel-induced Neuropathic Pain Require Activation of the Sphingosine 1-Phosphate Receptor Subtype 1. J Biol Chem. 2014, Jul 25;289(30):21082-21097. Epub 2014 May 29.