eu.skepner AT skepner.eu
Experienced computer programmer in different areas (since 1984):
Tool-set for antigenic cartography (computational biology).
SyncML based phonebook backup system for mobile phones.
Visualizing the results of search in document collections.
Reliable email based documents distribution system.
Implementation of feasible directions global optimization method with non-linear constraints.
Framework for accessing various image formats used by the high-end graphic arts market.
X11-protocol recorder and playback system.
Programming languages: C++, Python3, Haskell, Javascript/Coffeescript/Typescript, Elisp, Bash.
Prior: Perl, Java, Pascal.
Platforms: MacOSX, Linux, UNIX.
GitHub: skepner
Linkedin: skepner
Xing: Eugene_Skepner
Facebook: eugene.skepner
Instagram: skepnereu
2015
Global circulation patterns of seasonal influenza viruses vary with antigenic drift. Bedford T, Riley S, Barr IG, Broor S, Chadha M, Cox NJ, Daniels RS, Gunasekaran CP, Hurt AC, Kelso A, Klimov A, Lewis NS, Li X, McCauley JW, Odagiri T, Potdar V, Rambaut A, Shu Y, Skepner E, Smith DJ, Suchard MA, Tashiro M, Wang D, Xu X, Lemey P, Russell CA. Nature. 2015 Jun 8. doi: 10.1038/nature14460. PMID: 26053121
2014
Back-boost of antibody landscapes after influenza virus infection and vaccination, J. M. Fonville, S. H. Wilks, S. L. James, M. Aban, L. Xue, T. C. Jones, M. Ventresca, A. Fox, Le N. M. H., Pham Q. T., Tran N. D., Y. Wong?, A. Mosterin, L. C. Katzelnick, G. van der Net, E. Skepner, C.A. Russell, T. D. Kaplan, G. F. Rimmelzwaan, N. Masurel, J. C. de Jong, A. Palache, W. E. P. Beyer, Le Q. M., Nguyen T. H., H. Wertheim, A. Hurt, A. D. M. E. Osterhaus, I.G. Barr, R. A. M. Fouchier, P. Horby, D. J. Smith. Science.
Antigenic variation of clade 2.1 H5N1 virus is determined by a few amino acid substitutions immediately adjacent to the receptor binding site.Koel BF1, van der Vliet S1, Burke DF, Bestebroer TM1, Bharoto EE2, Yasa IW2, Herliana I2, Laksono BM, Xu K3, Skepner E, Russell CA, Rimmelzwaan GF1, Perez DR3, Osterhaus AD1, Smith DJ, Prajitno TY2, Fouchier RA4.MBio. 2014 Jun 10;5(3):e01070-14. doi: 10.1128/mBio.01070-14.
Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine. Lewis NS, Anderson TK, Kitikoon P, Skepner E, Burke DF, Vincent AL. J Virol. 2014 May;88(9):4752-63. doi: 10.1128/JVI.03805-13. Epub 2014 Feb 12.
2013
Genome-wide Analysis of Reassortment and Evolution of Human Influenza A(H3N2) Viruses Circulating between 1968 and 2011. Westgeest, K; Russell, C; Lin, X; Spronken, M; Bestebroer, T; Bahl, J; van Beek, R; Skepner, E; Halpin, R; de Jong, J; Rimmelzwaan, G; Osterhaus, A; Smith, D; Wentworth, D; Fouchier, R; De Graaf, M. ASM Journals.J Virol. 2014 Mar; 88(5):2844-57. doi: 10.1128/JVI.02163-13. Epub 2013 Dec 26.
Substitutions near the receptor binding site determine major antigenic change during influenza virus evolution. Koel, BF; Burke, DF; Bestebroer, TM; van der Vliet, S; Zondag, GCM; Vervaet, G; Skepner, E; Lewis, NS; Spronken, MIJ; Russell, CA; Eropkin, MY; Hurt, AC; Barr, IG; de Jong, JC; Rimmelzwaan, GF; Osterhaus, ADME; Fouchier, RAM; Smith, DJ. Science. 2013 Nov 22; 342, 976 (2013); DOI: 10.1126/science.1244730
2011
The antigenic and genetic evolution of equine influenza A(H3N8) virus from 1968-2007. Lewis NS, Daly JM, Russell CA, Horton DL, Skepner E, Bryant NA, Burke DF, Rash AS, Wood JL, Chambers TM, Fouchier RA, Mumford JA, Elton DM, Smith DJ. J Virol 2011 Sep 21.
2009
Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans. Garten RJ, Davis CT, Russell CA, Shu B, Lindstrom S, Balish A, Sessions WM, Xu X, Skepner E, Deyde V, Okomo-Adhiambo M, Gubareva L, Barnes J, Smith CB, Emery SL, Hillman MJ, Rivailler P, Smagala J, de Graaf M, Burke DF, Fouchier RA, Pappas C, Alpuche-Aranda CM, López-Gatell H, Olivera H, López I, Myers CA, Faix D, Blair PJ, Yu C, Keene KM, Dotson PD Jr, Boxrud D, Sambol AR, Abid SH, St George K, Bannerman T, Moore AL, Stringer DJ, Blevins P, Demmler-Harrison GJ, Ginsberg M, Kriner P, Waterman S, Smole S, Guevara HF, Belongia EA, Clark PA, Beatrice ST, Donis R, Katz J, Finelli L, Bridges CB, Shaw M, Jernigan DB, Uyeki TM, Smith DJ, Klimov AI, Cox NJ (2009). Science, doi 10.1126/science.1176225.
2008
The global circulation of seasonal influenza A(H3N2) viruses. Russell CA, TC Jones, IG Barr, NJ Cox, R Garten, V Gregory, I Gust, AW Hampson, AJ Hay, AC Hurt, JC de Jong, AI Klimov, T Kageyama, N Komadina, AS Lapedes, YP Lin, A Mosterin, M Obuchi, T Odagiri, ADME Osterhaus, GF Rimmelzwaan, MW Shaw, E Skepner, K Stohr, M Tashiro, RAM Fouchier, DJ Smith. Science, Vol. 320, No. 5874. (18 April 2008), pp. 340-346.
Influenza vaccine strain selection and recent studies on the global migration of seasonal influenza viruses. Russell CA, TC Jones, IG Barr, NJ Cox, R Garten, V Gregory, I Gust, AW Hampson, AJ Hay, AC Hurt, JC de Jong, AI Klimov, T Kageyama, N Komadina, AS Lapedes, YP Lin, A Mosterin, M Obuchi, T Odagiri, ADME Osterhaus, GF Rimmelzwaan, MW Shaw, E Skepner, K Stohr, M Tashiro, RAM Fouchier, DJ Smith. Vaccine, 26:D31-34.
2001
LetterWise: Prefix-based Disambiguation for Mobile Text. LetterWise: Prefix-based Disambiguation for Mobile Text. 14th ACM Symposium on User Interface Software and Technology. 2001. pp. 111-120.
Linguistically Optimized Text Entry on a Cell Phone. Hedy Kober, Eugene Skepner, Howard Gutowitz and Scott MacKenzie. Unpublished research report.