- B.S. Neuroscience & B.A. History, University of Pittsburgh, 2004
- Ph.D. Biomedical Sciences, University of California, San Diego, 2009
- Postdoctoral Fellowship in Research and Scientific Teaching, Emory University, 2009-2012
- Biology 136, Vertebrate Neurophysiology
- Biology 167, Cardiorespiratory Physiology (offered as Biol 145L & Biol 184 in Fall 2013)
- Biology 255P, Pain: From Molecule to Perception
My lab studies plasticity in the sensory system, particularly of the sensory neurons that innervate skeletal muscle. Muscles have many sensory neurons that constantly monitor muscle stretch, tension, temperature, pH, pain, and more. Improper activation of these sensory neurons can lead to pathologies like chronic pain or impaired balance and movement. To study muscle sensory neurons we use an isolated mouse muscle nerve preparation where we can directly record changes in sensory nerve firing properties in response to disease states, drugs, or a variety of other perturbations. Currently we are investigating the response of muscle sensory neurons to inflammation and obesity.
J.A. Franco, H.E. Kloefkorn, S. Hochman, K.A. Wilkinson (2014) An In Vitro Adult Mouse Muscle-nerve Preparation for Studying the Firing Properties of Muscle Afferents. J. Vis. Exp. (91), e51948, doi:10.3791/51948.
K.A. Wilkinson, H.E. Kloefkorn*, S. Hochman (2012) Characterization of Muscle Spindle Afferents in the Adult Mouse Using an In Vitro Muscle-Nerve Preparation. PLoS ONE 7(6): e39140. doi:10.1371/journal.pone.0039140
K.A. Wilkinson, Z. Fu, F.L. Powell (2011).
Ventilatory effects of substance P-saporin lesions in the Nucleus Tractus
Solitarii of chronically hypoxic rats. Am J Physiol Regul Integr Comp Physiol.
K.A. Wilkinson, K.A. Huey, B. Dinger, L. He, S.J. Fidone, F.L. Powell (2010). Chronic hypoxia increases the gain of the hypoxic ventilator response by a mechanism in the central nervous system. J Appl Physiol. 109(2):424-30.* denotes undergraduate researcher
Back to SJSU Department of Biological Sciences