Publications and Dissemination

1.        O’Hurley, G., Busch, C., Fagerberg, L., Hallstrom, B.M., Stadler, C., Tolf, A., Lundberg, E., Schwent, J.M., Jirstrom, K., Bjartell, A., Gallagher, W.M., Uhlén, M., Pontén, F. Analysis of the human prostate-specific proteome defined by transcriptomics and antibody-based profiling identified TMEM79 and ACOXL as two putative, diagnostic markers in prostate cancer. PLOS One 2015; 10(8): e0133449.

 

2.        Canesin G., Evans-Axelsson S., Hellsten R., Sterner O., Krzyzanowska A., Andersson T., Bjartell A. The STAT3 Inhibitor Galiellalactone Effectively Reduces Tumor Growth and Metastatic Spread in an Orthotopic Xenograft Mouse Model of Prostate Cancer. European Urology. 2015 Jul 2. S0302-2838(15)00519-9.

 

3.        Prencipe M, O'Neill A, O'Hurley G, Nguyen LK, Fabre A, Bjartell A, Gallagher WM, Morrissey C, Kay EW, Watson RW. Relationship between Serum Response Factor and Androgen Receptor in prostate cancer. Prostate. 2015;75(15):1704-17.

 

4.        McArt, D.G., Blayney, J.K., Boyle, D.P., Irwin, G.W., Moran, M., Hutchinson, R.A., Bankhead, P., Kieran, D., Wang, Y., Dunne, P.D., Kennedy, R.D., Mullan, P.B., Harkin, D.P., Catherwood, M.A., James, J.A., Salto-Tellez, M., Hamilton, P.W. PICan: An integromics framework for dynamic cancer biomarker discovery. Molecular Oncology 2015; 9, 1234-1240.

 

5.        Wang, Y., McManus, D.T., Arthur, K., Johnston, B.T., Kennedy, A.J., Coleman, H.G., Murray, L.J., Hamilton, P.W. Whole slide image cytometry: a novel method to detect abnormal DNA content in Barrett’s esophagus. Laboratory Investigation, 2015;95, 1319-1330.

 

6.     Murphy* L, Prencipe* M, Gallagher WM & Watson RW. Commercialized Biomarkers: New Horizons in Prostate Cancer Diagnostics. Expert Review of Molecular Diagnostics, 2015;15(4):491-503. * Equal contribution

 

7.     Hamilton, P.W., Wang, Y., Boyd, C., James, J.A., Loughrey, M.B., Hougton, J.P., Boyle, D.P., Kelly, P., Maxwell, P., McCleary, D., Diamond, J., McArt, D.G., Tunstall, J., Bankhead, P., Salto-Tellez, M. Automated tumor analysis for molecular profiling in lung cancer. Oncotarget 2015; 6(29) 27938-27952.

 

8.        O’Hurley G, Sjöstedt E, Rahman A, Li B, Kampf C, Pontén F, Gallagher WM, Lindskog C. Garbage in, Garbage out: A Critical Evaluation of Strategies Used for Validation of Immunohistochemical Biomarkers . Molecular Oncology 2014); 8(4):783-98.

 

9.      Fitzgerald KA, Evans JC, McCarthy J, Guo J, Prencipe M, Kearney M, Watson WR, O'Driscoll CM. The role of transcription factors in prostate cancer and potential for future RNA interference therapy. Expert Opinion on Therpeutic Targets 2014 Jun;18(6):633-49.

 

10.    O’Hurley G*, Prencipe M*, Lundon D, O’Neill A, Boyce S, O’Grady A, Gallagher WM, Morrissey C, Kay EW and Watson RWG. The analysis of Serum Response Factor expression in bone and soft tissue Prostate Cancer metastases. Prostate 2014 Feb;74(3):306-13  * Equal contribution.

 

11.    Prencipe M, Madden SF, O’Neill A, O’Hurley G, Culhane A., O’ Connor D, Klocker H, Kay EW, Gallagher WM, Watson WR. Identification of transcription factors associated with castration-resistance: is the serum responsive factor a potential therapeutic target? Prostate 2013; 73(743-753). 

 

12.  Lynn MA, O’Hurley G, Coyle A, Balint B, Alamanou M, and Gallagher WM (2013) Biomarkers in drug discovery and development. Encyclopedia of Pharmaceutical Science and Technology, 4th edition, Informa Healthcare.

 

13.    Danielsson F, Skogs M, Huss M, Rexhepaj E, O’Hurley G, Klevebring D, Pontén F, Gad AKB, Uhlén M, Lundberg E. Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model.  Proceedings of the National Academy of Science 2013; 110(17) 6853-8.

 

14.    Lippolis G, Edsjo A, Stenman U-H, Bjartell A. A high-density tissue microarray from patients with clinically localized prostate cancer reveals ERG and TATI exclusivity in tumor cells. Prostate Cancer Prostatic Disease 2013; 16(2) 145-50.

 

15.    Lippolis, G., Edsjö, A., Helczynski, L., Bjartell, A., and Overgaard, N.C. Automatic registration of multi-modal microscopy images for integrative analysis of prostate tissue sections. BMC Cancer 2013; 13:408.


InterTradeIreland, Collaborate to Innovate - European Research and Innovation Funding for SMEs - Programme http://www.intertradeireland.com/fp72012/programme/ - FastPath Case study presentation video http://iti.radiovideo.co.uk/video/113048164