Figure 2. Dermatophyte serpins aligned with human alpha-1-antitrypsin (UniProt ID: P01009). Numbering is that of the mature form of alpha-1-antitrypsin. Secondary structure elements shown above the alignment were derived from the structure determined for the same protein (PDB ID: 1QLP)(54). Conserved residues are shown in red font with identical residues in white on a red background. The conserved positions specified in the serpin HMM profile PF00079 are marked with blue triangles. The RCL location is indicated by a gray bar and the RCL16 and RCL17 P1 residues are labeled. The alignment was formatted with ESPript (58).
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