Journal Articles

1.          Aronstam, R.S., L.G. Abood and J. Baumgold, Role of phospholipids in muscarinic binding by neural membranes, Biochem. Pharmacol. 26:1689-1695, 1977.

2.          Aronstam, R.S., L.G. Abood and M.K. MacNeil, Muscarinic cholinergic binding in human erythrocyte membranes, Life Sci. 20:1175-1180, 1977.

3.          Aronstam, R.S., W. Hoss and L.G. Abood, Conversion between configurational states of the muscarinic receptor in rat brain, Eur. J. Pharmacol. 46: 279-282, 1977.

4.          Baumgold, J., L.G. Abood and R.S. Aronstam, Studies on the relationship of binding affinity to psychoactive and anticholinergic potency of a group of psychotomimetic glycolates, Brain Res. 124:331-340, 1977.

5.          Aronstam, R.S., L.G. Abood and W. Hoss, Influence of sulfhydryl reagents and heavy metals on the functional state of the muscarinic acetylcholine receptor in rat brain, Molec. Pharmacol. 14: 575-586, 1978.

6.          Aronstam, R.S., D.C. Schuessler and M.E. Eldefrawi, Solubilization of muscarinic acetylcholine receptors of bovine brain, Life Sci. 23: 1377-1382, 1978.

7.          Aronstam, R.S., C. Kellogg and L.G. Abood, Development of muscarinic cholinergic receptors in inbred strains of mice:  Identification of receptor heterogeneity and relation to audiogenic seizure susceptibility, Brain Res. 162: 231-241, 1979.

8.          Aronstam, R.S., D.J. Triggle and M.E. Eldefrawi, Structural and stereochemical requirements for muscarinic receptor binding, Molec. Pharmacol. 15: 227-235, 1979.

9.          Aronstam, R.S. and M.E. Eldefrawi, Reversible conversion between affinity states for agonists of the muscarinic acetylcholine receptor from rat brain, Biochem. Pharmacol 28: 701-703, 1979.

10.       Aronstam, R.S. and M.E. Eldefrawi, Transition and heavy metal inhibition of ligand binding to muscarinic acetylcholine receptors from rat brain, Toxicol. Appl. Pharmacol. 48: 489-496, 1979.

11.       Ikeda, S.R., R.S. Aronstam and M.E. Eldefrawi, Nature of regional and chemically-induced differences in the binding properties of muscarinic acetylcholine receptors from rat brain, Neuropharmacology 19: 575-585, 1980.

12.       Tsai, M.-C., E.X. Albuquerque, R.S. Aronstam, A.T. Eldefrawi, D.J. Triggle and M.E. Eldefrawi, Sites of action of phencyclidine:  I. Effects on the electrical excitability and chemosensitive properties of the neuromuscular junction of skeletal muscle, Molec. Pharmacol. 18:  159-166, 1980.

13.       Albuquerque, E.X., M.-C. Tsai, R.S. Aronstam, A.T. Eldefrawi and M.E. Eldefrawi, Sites of action of phencyclidine:  II. Interaction with the ionic channel of the nicotinic receptor, Molec. Pharmacol. 18: 167-178, 1980.

14.       Aronstam, R.S., M.E. Eldefrawi, A.T. Eldefrawi, E.X. Albuquerque, K.F. Jim and D.J. Triggle, Sites of action of phencyclidine:  III. Interactions with muscarinic receptors, Molec. Pharmacol. 18: 179-184, 1980.

15.       Albuquerque, E.X., M.-C. Tsai, R.S. Aronstam, B. Witkop, A.T. Eldefrawi and M.E. Eldefrawi, Phencyclidine interactions with ionic channel of the acetylcholine receptor and electrogenic membrane, Proc. Natl. Acad. Sci. 77: 1224-1228, 1980.

16.       Aronstam, R.S., A.T. Eldefrawi and M.E. Eldefrawi, Similarities in the binding sites of the muscarinic receptor and the ionic channel of the nicotinic receptor, Biochem. Pharmacol. 29: 1311-1314, 1980.

17.       Eldefrawi, M.E., R.S. Aronstam, N.M. Bakry, A.T. Eldefrawi and E.X. Albuquerque, Activation, inactivation and desensitization of acetylcholine receptor channel complex detected by binding of perhydrohistrionicotoxin, Proc. Natl. Acad. Sci. USA 77: 2309-2313, 1980.

18.       Eldefrawi, M.E., A.T. Eldefrawi, R.S. Aronstam, M.A. Maleque, J.E. Warnick, and E.X. Albuquerque, [3H]Phencyclidine: a probe for the ionic channel of the nicotinic receptor, Proc. Natl. Acad. Sci. USA 77: 7458-7462, 1980.

19.       Aronstam, R.S., A.T. Eldefrawi, I.N. Pessah, J.W. Daly, E.X. Albuquerque and M.E.Eldefrawi, Regulation of [3H]perhydrohistrionicotoxin binding to Torpedo ocellata electroplax by effectors of the acetylcholine receptor, J. Biol. Chem. 256: 2843-2850, 1981.

20.       Aronstam, R.S., Interactions of tricyclic antidepressants with a synaptic ion channel, Life Sci. 28: 59-64, 1981.

21.       Buccafusco, J.J. and R.S. Aronstam, Cholinergic actions of false neurotransmitters: Acetylpyrrolidine-choline, Neurosci. Lett. 23: 319-324, 1981.

22.       Aronstam, R.S. and B. Witkop, Anatoxin-a interactions with cholinergic synaptic molecules, Proc. Natl. Acad. Sci. USA 78: 4639-4643, 1981.

23.       Aronstam, R.S. and L. Narayanan, 3-Chlorodibenzepine binding to cholinergic receptors and ion channels, Res. Commun. Chem. Pathol. Pharmacol. 34: 551-554, 1981.

24.       Aronstam, R.S. and J.J. Buccafusco, Cholinergic actions of false neurotransmitters: Acetyldiethylcholine, Neurosci. Lett. 28: 51-56, 1982.

25.       Aronstam, R.S., L. Narayanan and D.A. Wenger, Ketamine inhibition of ligand binding to cholinergic receptors and ion channels, Eur. J. Pharmacol. 78: 367-370, 1982.

26.       Aronstam, R.S. and G.O. Carrier, Influence of N-ethylmaleimide on cholinoceptors and responses in longitudinal muscle from guinea pig ileum, Br. J. Pharmacol. 77: 89-95, 1982.

27.       Aronstam, R.S., J.L. Graham and L. Narayanan, Receptor-ion channel interactions in Torpedo electric organ:  Influence of thiol group modification, Neurosci. Lett. 31: 53-58, 1982.

28.       Kirby, M.L. and R.S. Aronstam, Levorphanol-sensitive [3H]naloxone binding in developing brainstem following prenatal morphine exposure, Neurosci. Lett. 35: 191-195, 1983.

29.       Carp. J.S., R.S. Aronstam, B. Witkop and E.X. Albuquerque, Electrophysiological and biochemical studies on enhancement of desensitization by phenothiazene neuroleptics, Proc. Natl. Acad. Sci. USA 80: 310-314, 1983.

30.       Carrier, G.O., D.C. Marshall and R.S. Aronstam, Calcium uptake by intestinal smooth muscles. Influence of alkylation, Eur. J. Pharmacol.  89: 173-175, 1983.

31.       Kirby, M.L. and R.S. Aronstam, Atropine-induced alterations of normal development of muscarinic receptors in the embryonic chick heart, J. Molec. Cell. Cardiol. 15: 685-696, 1983.

32.       King, C.T. and R.S. Aronstam, Benzomorphan interactions with acetylcholine receptor complexes from Torpedo, Eur. J. Pharmacol. 90: 419-422, 1983.

33.       Pascuzzo, G.J., A. Akaike, M.A. Maleque, K.-P. Shaw, R.S. Aronstam, D.L. Rickett and E.X. Albuquerque, The nature of the interactions of pyridostigmine with the nicotinic acetylcholine receptor-ionic channel complex. I. Agonist, desensitizing and binding properties, Molec. Pharmacol. 25: 92-101, 1984.

34.       Souccar, C., W.A. Varanda, R.S. Aronstam, J.W. Daly and E.X. Albuquerque, Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex.  II. Enhancement of desensitization, Molec. Pharmacol. 25: 395-400, 1984.

35.       Carrier, G.O., A.D. Edwards and R.S. Aronstam, Cholinergic supersensitivity and decreased number of muscarinic receptors in atria from short-term diabetic rats, J. Molec. Cell. Cardiol. 16: 963-965, 1984.

36.       Ikeda, S.R., R. S. Aronstam, J.W. Daly, Y. Aracava and E.X. Albuquerque, Interactions of bupivicaine with ionic channels of the nicotinic receptor: Electrophysiological and biochemical studies, Molec. Pharmacol. 26: 293-303, 1984.

37.       Aronstam, R.S. and L.M. Greenbaum, Guanine nucleotide sensitivity of muscarinic acetylcholine receptors from rat brainstem is eliminated by endogenous proteolytic activity, Neurosci. Lett.47:131-137, 1984.

38.       Parthasarathy, N., C. Pickard and R.S. Aronstam, Influence of phospholipase C on muscarinic acetylcholine receptor binding in rat brain, Neurochem. Res. 9: 709-717, 1984.

39.       Eason, K.E. and R.S. Aronstam, Influence of sulfhydryl reagents on potassium-stimulated calcium uptake by rat brain synaptosomes, Res. Commun. Chem. Pathol. Pharmacol., 44:503-506, 1984.

40.       Aronstam, R.S. and W. Hoss, Tricyclic antidepressant inhibition of depolarization-induced uptake of calcium by synaptosomes from rat brain, Biochem. Pharmacol. 34:902-904, 1985.

41.       Wenger, D.A. and R.S. Aronstam, Regional heterogeneity of muscarinic acetylcholine receptors from rat brain is retained after detergent solubilization, Neurosci. Lett. 54: 65-70, 1985.

42.       Aronstam, R.S., C.T. King, E.X. Albuquerque, J.W. Daly and D.M. Feigl, Binding of [3H]perhydro-histrionicotoxin and [3H]phencyclidine to the nicotinic receptor-ion channel complex of Torpedo electroplax:  Inhibition by histrionicotoxins and derivatives, Biochem. Pharmacol. 34: 3037-3047, 1985.

43.       Kirby, M.L., R.S. Aronstam and J.J. Buccafusco, Changes in cholinergic parameters associated with failure of conotruncal septation in embryonic chick hearts after neural crest ablations, Circ. Res. 56: 392-401, 1985.

44.       Dennison, R.L., D.A. Wenger and R.S. Aronstam, Biphasic regulation of detergent-solubilized muscarinic acetylcholine receptors from rat cerebral cortex by N-ethylmaleimide, Res. Commun. Chem. Pathol. Pharmacol., 47: 465-468, 1985.

45.       Aronstam, R.S., M.L. Kirby and M. Smith, Muscarinic acetylcholine receptors in chick heart: Influence of heat and N-ethylmaleimide on receptor conformations and interactions with guanine nucleotide-dependent regulatory proteins, Neurosci. Lett. 54: 289-294, 1985.

46.       McKay, D.B., R.S. Aronstam and A.S. Schneider, Interactions of microtubule-active agents with nicotinic acetylcholine receptors:  Relationship to their inhibition of catecholamine secretion by adrenal chromaffin cells, Molec. Pharmacol.  28:10-16, 1985.

47.       Aronstam, R.S., B.L. Anthony and R.L. Dennison, Jr., Halothane effects on muscarinic acetylcholine receptor complexes in rat brain, Biochem. Pharmacol.  35: 667-672, 1986.

48.       Anthony, B.L. and R.S. Aronstam, Effect of pH on muscarinic receptors from rat brainstem, J. Neurochem.  46: 556-561, 1986.

49.       Stewart, D.E., M.L. Kirby and R.S. Aronstam, Regulation of beta-adrenergic receptor density in the non-innervated and denervated chick heart, J. Molec. Cell. Cardiol. 18: 469-475, 1986.

50.       Aronstam, R.S. and J.-S. Hong, Interactions of chlordecone (kepone) and mirex with the nicotinic acetylcholine receptor-ion channel complex, Toxicol. Lett. 30: 247-251, 1986.

51.       Swanson, K.L., C.N. Allen, R.S. Aronstam, H. Rapoport and E.X. Albuquerque, Molecular mechanisms of the potent and stereospecific nicotinic receptor agonist (+)-anatoxin-a, Molec. Pharmacol. 29: 250-257, 1986.

52.       Aronstam, R.S., J.W. Daly, T.F. Spande, T.K. Narayanan and E.X. Albuquerque, Interaction of gephyrotoxin and indolizidine alkaloids with the nicotinic acetylcholine receptor-ion channel complex of Torpedo electroplax, Neurochem. Res. 11: 1227-1240, 1986.

53.       Narayanan, T.K. and R.S. Aronstam, Allosteric effect of gallamine on muscarinic cholinergic receptor binding: Influence of guanine nucleotides and conformational state, Neurochem. Res. 11: 1397-1406, 1986.

54.       Aronstam, R.S., M.D. Smith and J.J. Buccafusco, Clonidine protection from soman and echothiophate toxicity in mice, Life Sci. 39:2097-2102, 1986.

55.       Buccafusco, J.J. and R.S. Aronstam, Clonidine protection from the toxicity of soman, an organophosphate acetylcholinesterase inhibitor, in the mouse, J. Pharmacol. Exp. Ther., 239:43-47, 1986.

56.       Anthony, B.L. and R.S. Aronstam, High affinity binding to rat brainstem muscarinic receptors is eliminated by low pH, Neurosci. Lett. 69:84-88, 1986.

57.       Molloy, A.G., R.S. Aronstam and J.J. Buccafusco, Selective antagonism by clonidine of the stereotyped and non-stereotyped motor activity elicited by atropine, Pharmacol. Biochem. Behav. 25:985-988, 1986.

58.       Dennison, R.L., B.L. Anthony, T.K. Narayanan and R.S. Aronstam, Effects of halothane on high affinity agonist binding and guanine nucleotide sensitivity of muscarinic acetylcholine receptors from brainstem of rat, Neuropharmacology 16: 1201-1205, 1987.

59.       Aronstam, R.S., M.D. Smith and J.J. Buccafusco, Clonidine prevents the short-term down regulation of muscarinic receptors in mouse brain induced by the acetylcholinesterase inhibitor soman, Neurosci. Lett. 78:107-112, 1987.

60.       Buccafusco, J.J. and R.S. Aronstam, Adrenergic agonists protect against soman, an irreversible acetyl-cholinesterase inhibitor, Toxicol. Lett. 38:67-76, 1987.

61.       Carrier, G.O. and R.S. Aronstam, Altered muscarinic receptor properties and function in the heart in diabetes, J. Pharmacol. Exp. Ther. 242: 531-535, 1987.

62.       Aronstam, R.S., M.W. Edwards, J.W. Daly and E.X. Albuquerque, Interactions of piperidine derivatives with the nicotinic cholinergic receptor complex from Torpedo electric organ, Neurochem. Res. 13: 171-176, 1988.

63.       Aronstam, R.S., D.C. Marshall and J.J. Buccafusco, Cholinergic false transmitters:  Physiological and biochemical actions in central and peripheral systems, Neuropharmacology  27: 217-225, 1988.

64.       Buccafusco, J.J. and R.S. Aronstam, Precursors of cholinergic false transmitters:  Central effects on blood pressure and direct interactions with cholinergic receptors, Neuropharmacology  27:227-233, 1988.

65.       Buccafusco, J.J., J.H. Graham and R.S. Aronstam, Behavioral effects of toxic doses of soman, an organophosphate cholinesterase inhibitor, in the rat:  Protection afforded by clonidine, Pharmacol. Biochem. Behav.  29:309-313, 1988.

66.       Aronstam, R.S. and T.K. Narayanan, Temperature effect on the detection of receptor-G protein interactions in ligand binding assays, Biochem. Pharmacol. 37: 1045-1049, 1988.

67.       Narayanan, T.K., R.A. Confer, R.L. Dennison, B.L. Anthony and R.S. Aronstam, Halothane attenuation of  muscarinic inhibition of adenylate cyclase in rat heart, Biochem. Pharmacol. 37:1219-1223, 1988.

68.       Anthony, B.L., R.L. Dennison, T.K. Narayanan and R.S. Aronstam, Diethyl ether effects on muscarinic acetylcholine receptor complexes in rat brainstem, Biochem. Pharmacol. 37:4041-4046, 1988.

69.       Magri, V., J.J. Buccafusco and R.S. Aronstam, Protection by clonidine from the cardiovascular changes and lethality following soman administration in the rat:  Role of brain acetylcholine, Toxicol. Appl. Pharmacol.  95: 464-473, 1988.

70.       Buccafusco, J.J., R.S. Aronstam and J.H. Graham, Role of central biogenic amines in the protection afforded by clonidine against the toxicity of soman, an irreversible cholinesterase inhibitor, Toxicol. Lett. 42:291-299, 1988.

71.       Hannan, C.J., T.M. Kettler, A.A. Artru and R.S. Aronstam, Blood-brain barrier permeability during hypocapnia in halothane-anesthetized monkeys, Ann. N.Y. Acad. Sci., 529:172-174, 1988.

72.       Swanson, K.L., Y. Aracava, F.J. Sardina, H. Rapoport, R.S. Aronstam and E.X. Albuquerque, N-methylanatoxinol isomers:  Derivatives of the agonist (+)-anatoxin-a block the nicotinic acetylcholine receptor ion channel, Molec. Pharmacol.  35:223-231, 1989.

73.       Legrand, A., T.K. Narayanan, U.S. Ryan, R.S. Aronstam and J.D. Catravas, Modulation of adenylate cyclase activity in cultured bovine pulmonary arterial endothelial cells:  Effects of adenosine and derivatives, Biochem. Pharmacol.  38:423-430, 1989.

74.       Buccafusco, J.J., J.H. Graham, J. VanLingen and R.S. Aronstam, Protection afforded by clonidine from the acute and chronic behavioral toxicity produced by the cholinesterase inhibitor soman, Neurotoxicol. Teratol. 11:39-44, 1989.

75.       Spivak, C.E., J.A. Waters and R.S. Aronstam, Binding of semirigid, cholinergic agonists to nicotinic and muscarinic receptors, Molec. Pharmacol.  36:177-184, 1989.

76.       Anthony,  B.L., R.L. Dennison and R.S. Aronstam, Disruption of muscarinic receptor-G protein coupling is a general property of liquid volatile anesthetics, Neurosci. Lett., 99:191-196, 1989.

77.       Aronstam, R.S. and G.O. Carrier, Insulin prevention of altered muscarinic receptor-G protein coupling in diabetic rat atria,  Diabetes 38:1611-1616, 1989.

78.       Costa, A.C.S., K.L. Swanson, Y. Aracava, R.S. Aronstam, M. Howard, H. Rapoport, E.X. Albuquerque, Molecular effects of dimethylanatoxin on the peripheral nicotinic acetylcholine receptor, J. Pharmacol. Exp. Ther. 252:507-516, 1990.

79.       Baumgartner, M.K., R.L. Dennison, T.K. Narayanan and R.S. Aronstam, Halothane disruption of 2-adrenergic receptor-mediated inhibition of adenylate cyclase and receptor-G protein coupling in rat brain, Biochem. Pharmacol.  39:223-225, 1990.

80.       Kofuji, P., Y. Aracava, K.L. Swanson, R.S. Aronstam, H. Rapoport and E.X. Albuquerque, Activation and blockade of the acetylcholine receptor-ion channel by the agonists (+)-anatoxin-a, the N-methyl derivative and the enantiomer, J. Pharmacol. Exp. Ther. 252:517-525, 1990.

81.       Martin, D.C., R.J. Adams and R.S. Aronstam, Effects of enflurane on 5-hydroxytryptamine transport in synaptosomes from rat brain, Biochem. Pharmacol. 40:187-192, 1990.

82.       Legrand, A.B., T.K. Narayanan, U.S. Ryan, R.S Aronstam and J.D. Catravas, Effects of adenosine and analogs on adenylate cyclase activity in cultured bovine aortic endothelial cells, Biochem. Pharmacol.  40:1103-1109, 1990.

83.       Ravindra, R. and R.S. Aronstam, Influence of anti-tubulin antibodies on muscarinic receptor modulation of G protein GTPase activity in rat striatum, Biochem. Pharmacol. 40:457-463, 1990.

84.       Martin, D.C., R.P. Introna and R.S. Aronstam, Inhibition of neuronal 5-HT uptake by ketamine, but not halothane, involves disruption of substrate recognition by the transporter, Neurosci. Lett., 112:99-103. 1990.

85.       Martin, D.C., R.J. Adams and R.S. Aronstam, The influence of isoflurane on the synaptic activity of 5-hydroxytryptamine, Neurochem. Res. 15:969-973, 1990.

86.       Anthony, B.L., R.L. Dennison and R.S. Aronstam, Influence of volatile anesthetics on muscarinic regulation of adenylate cyclase activity, Biochem. Pharmacol. 40:376-379, 1990.

87.       Carrier, G.O. and R.S. Aronstam, Increased muscarinic responsiveness and decreased muscarinic receptor content in ileal smooth muscle in diabetes, J. Pharmacol. Exp. Ther.  254:445-449, 1990.

88.       Ramoa, A.S., M. Alkondon, Y. Aracava, J. Irons, G.G. Lunt, S.S. Deshpande, S. Wonnacott, R.S. Aronstam and E.X. Albuquerque, The anticonvulsant MK-801 interacts with peripheral and central nicotinic acetylcholine receptor ion channels, J. Pharmacol. Exp. Ther.  254:71-82, 1990.

89.       Nishizawa, Y., K.B. Seamon, J.W. Daly and R.S. Aronstam, Effects of forskolin and analogs on nicotine receptor-mediated sodium flux, voltage-dependent calcium flux and voltage-dependent rubidium efflux in pheochromocytoma PC12 cells, Cell. Molec. Neurobiol.  10:351-368, 1990.

90.       Aronstam, R.S., R.L. Elkins and P.A. Walters, Muscarinic acetylcholine receptor densities in brains of genetically selected taste-aversion prone and resistant rats, Med. Sci. Res.  18:213-214, 1990.

91.       Aronstam, R.S., Alcohol and cell-cell communication in the brain, US J. Drug Alc. Depend., 1990.

92.       Ravindra, R. and R.S. Aronstam, Role of cytoskeleton in signal transduction:  Effect of vinblastine and deuterium oxide on acetylcholine stimulation of G protein GTPase activity in rat striatum, Life Sci. Adv. - Biochem. Pharmacol. 9:65-70, 1990.

93.       Alkondon, M., A.C.S Costa, V. Radhakrishnan, R.S. Aronstam and E.X. Albuquerque, Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead, FEBS Lett.  261:124-130, 1990.

94.       Ravindra R and R.S. Aronstam, Gonadotropin-releasing hormone and thyrotropion-releasing hormone regulationof G protein function in the rat anterior pituitary lobe, J. Neuroendocrin. 2:593-599, 1990.

95.       Martin, D.C., R.P. Introna and R.S. Aronstam, Fentanyl and sufentanil inhibit agonist binding to 5-HT1A receptors in rat brain membranes, Neuropharmacology 30:323-327, 1991.

96.       Daly, J.W., Y. Nishizawa, M.W. Edwards, J.A. Waters and R.S. Aronstam, Nicotinic receptor-elicited sodium flux in rat pheochromocytoma PC12 cells:  Effects of agonists, antagonists and noncompetitive blockers, Neuurochem. Res. 16:489-500, 1991.

97.       Daly, J.W., Y. Nishizawa, W.L. Padgett, T.Tokuyama, A.L. Smith, A.B. Holmes, C. Kibayashi and R.S. Aronstam, 5,8-Disubstituted indolizidines:  A new class of noncompetitive blockers for nicotinic receptor-channels, Neurochem. Res. 16:1213-1218, 1991.

98.       Daly, J.W., Y. Nishizawa, W.L. Padgett, T.Tokuyama, P.J. McCloskey, L. Waykole, A.G. Schultz and R.S. Aronstam, Decahydroquinoline alkaloids:  Noncompetitive blockers for nicotinic acetylcholine receptor-channels in pheochromocytoma cells and Torpedo electroplax, Neurochem. Res. 16:1207-1212, 1991.

99.       Ravindra, R. and R.S. Aronstam, Acetylcholine stimulates GTP binding to G proteins in rat striatum, NeuroReport 2:127-130, 1991.

100.     Martin, D.C., J.E. Abraham, M. Plagenhoef and R.S. Aronstam, Volatile anesthetics and NMDA receptors.  Enflurane inhibition of glutamate-stimulated [3H]MK-801 binding and reversal by glycine, Neurosci. Lett. 132:73-76, 1991.

101.     Martin, D.C., R.L. Dennison, R.P.S. Introna and R.S. Aronstam, Influence of halothane on the interactions of serotonin1A and adenosine A1 receptors with G proteins in rat brain membranes, Biochem. Pharmacol. 42:1313-1316, 1991.

102.     Ravindra, R. and R.S. Aronstam, Colchicine inhibits acetylcholine receptor stimulation of G protein GTPase activity in rat striatum, Pharmacology & Toxicology  69:259-262, 1991.

103.     Swanson, K.L., R.S. Aronstam, S. Wannacott, H. Rapoport and E.X. Albuquerque, Nicotinic pharmacology of anatoxin analogs. I. Side chain structure-activity relationships at peripheral agonist and noncompetitive antagonist sites, J. Pharmacol. Exp. Ther. 259:377-386, 1991.

104.     Pereira, E.F.R., Y. Aracava, R.S. Aronstam, E.J. Barreiro and E.X. Albuquerque, Pyrazole, an alcohol dehydrogenase inhibitor, has dual effects on N-methyl-d-aspartate receptors of hippocampal pyramidal cells:  agonist and non-competitive antagonist, J. Pharmacol. Exp. Ther. 261:331-340, 1992.

105.     Ravindra, R. and R.S. Aronstam, Progesterone, testosterone, and estradiol-17 inhibit gonadotropin-releasing hormone stimulation of G protein GTPase activity in plasma membranes from rat anterior pituitary lobe, Acta Endocinol. 126:345-349, 1992.

106.     Ravindra, R. and R.S. Aronstam, Stimulation of the release of [32P]GDP from G proteins in the rat anterior pituitary lobe by gonadotrophin-releasing and thyrotrophin-releasing hormones, J. Reprod. Fertil. 95:669-677, 1992.

107.     Aronstam, R.S., U.S. Ryan and J.D. Catravas, Muscarinic binding sites on bovine pulmonary arterial endothelial cells in culture, Pharmacology: 44:324-333, 1992.

108.     Ravindra, R. and R.S. Aronstam, Taxol inhibits acetylcholine receptor stimulation of G protein GTPase activity in rat striatum, Life Sci. Adv. - Biochem. 11:101-106, 1992.

109.     Martin, D.C., R.L. Dennison and R.S. Aronstam, Barbiturate interactions with N-methyl-d-aspartate (NMDA) receptors in rat brain, Molec. Neuropharmacol. 2:255-259, 1992.

110.     Martin, D.C., J.K. Pruett and R.S. Aronstam, Test tube equilibration of volatile anesthetic concentrations, Br. J. Anesthesiol. 70:365-367, 1993.

111.     Holland, L.N., B.D. Goldstein and R.S. Aronstam, Substance P receptor desensitization in the dorsal horn: Possible involvement of receptor-G protein complexes, Brain Research 600:89-96, 1993.

112.     Pereira, E.F.R., M. Alkondon, T. Tano, N.G. Castro, M.M. Froes-Ferrao, R. Rozental, R.S. Aronstam, A. Schrattenholz, A. Maelicke and E.X. Albuquerque, A novel agonist binding site on nicotinic acetylcholine receptors, J. Receptor Res.13:413-436, 1993.

113.     Ravindra, R. and R.S. Aronstam, Effect of colchicine and taxol on stimulation of G protein GTPase activity in anterior pituitary lobe of rats by gonadotrophin- and thyrotropin-releasing hormones, J. Reprod. Fertil. 97:27-33, 1993.

114.     Buccafusco, J.J., C.A. Lapp, R.S. Aronstam, A.C. Hays and L.C. Shuster, Role of prostanoids in the regulation of central cholinergic receptor sensitivity, J. Pharmcol. Exp. Ther. 266:314-322, 1993.

115.     Baumgartner, M.K., J. Wei and R.S. Aronstam, Retinoic acid-induced differentiation of a human neuro­blastoma cell line alters muscarinic receptor expression and activity, Dev. Brain Res. 72:305-308, 1993.

116.     Aronstam, R.S., R.L. Dennison, D.C. Martin and R. Ravindra, Ethanol disruption of muscarinic acetylcholine receptor-G protein interactions in rat brainstem revealed by ligand binding measurements, Neuroscience Research Communications, 12:175-182, 1993.

117.     Aronstam, R.S., D.C. Martin and R.L. Dennison, Volatile anesthetics inhibit NMDA-stimulated 45Ca uptake by rat brain microvesicles, Neurochemical Research 19: 1515-1520, 1994.

118.     Aronstam, R.S., D.C. Martin, R.L. Dennison and H.G. Cooley, S-Nitrosylation of m2 muscarinic receptor thiols disrupts receptor-G protein coupling, Annals NY Acad. Sci. 757:215-217, 1995.

119.     Martin, D.C., M. Plagenhoef, J. Abraham, R.L. Dennison and R.S. Aronstam, Volatile anesthetics and glutamate activation of N-methyl-d-aspartate receptors, Biochemical Pharmacology 49: 809-817, 1995.

120.     Martin, D.C. and Aronstam, R.S., Spermidine attenuation of volatile anesthetic inhibition of glutamate-stimulated [3H](5d,10S)–(+)–methyl–10,11–dihydro-5H–dibenzo[a,d] cyclohepten-5,10-imine ([3H]MK-80l) binding to N-methyl-d-aspartate (NMDA) receptors in rat brain, Biochemical Pharmacology 50: 1373–1377, 1995.

121.     Aronstam, R.S., The role of NMDA receptors in general anesthesia, Guthrie J. 64:59–69, 1995.

122.     Socci, R.R., S.D. Tachado, R.S. Aronstam and P.S. Reinach, Characterization of the muscarinic receptor subtypes in the bovine corneal epithelial cells, J. Ocul. Pharmacol Therap. 12:259-269, 1996.

123.     Puhl, H.L., C.L. Williams and R.S. Aronstam, Inhibition of M3 muscarinic acetylcholine receptor-mediated Ca2+ influx and intracellular Ca2+ mobilization in neuroblastoma cells by the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62, Biochemical Pharmacology 53:1107-1114, 1997.

124.     Chang, Z.L., H.L. Puhl, L.G. May, C.L. Williams and R.S. Aronstam, Influence of acute and chronic ethanol treatment on muscarinic responses and receptor expression in CHO cells, Biochemical Pharmacology 54:833-839, 1997.

125.     Stair, S.M., L.G. May, H.L. Puhl, C.L. Williams and R.S. Aronstam, Ethanol disrupts muscarinic receptor-mediated release of arachidonic acid from CHO cells expressing different subtypes of human muscarinic receptor, Alcoholism: Clinical and Experimental Research 22:409-415, 1998.

126.     May, L.G., S. Johnson, S. Krebs, A. Newman and R.S. Aronstam, Involvement of protein kinase C and protein kinase A in the muscarinic receptors signaling pathways mediating phospholipase C activation, arachidonic acid release and calcium mobilization, Cellular Signalling 11:179-187, 1999.

127.     Canney, D.J., M. Zhang, P.H. Doukas, C. Massakowski, R.S. Aronstam, M. Gattu and J.J. Buccafusco, Characterization of ethyl (3-quinuclidinyl) acetate (EQA_ as a ligand for acetylcholine receptors, Life Sciences 63:329+336, 1998.

128.     Strassheim, D., L.G. May, K.A. Varker, H.L. Puhl, S.H. Phelps, R.A. Porter, R.S. Aronstam, J.D. Noti and C.L. Williams, Regulation of cytoplasmic myosin by M3 muscarinic acetylcholine receptors requires conventional protein kinase C isoforms and involves Rho proteins, J. Biol. Chem. 274:18675-18685, 1999.

129.     Puhl, H.L., T.T. Shay, J.C. Mattison and R.S. Aronstam, Techniques for the characterization of gene structure with special reference to the 5'end of the human M3 muscarinic receptor gene, Guthrie J. 68:38-47, 1999.

130.     Puhl, H.L., R.S. Aronstam and S.R. Ikeda, The Guthrie cDNA Resource Center, Guthrie J.  70:58-64, 2001.

131.     Freije, J.E. and RS Aronstam, Physician participation in clinical research in a multispecialty clinic. American Group Practice   52:42-46, 2003.

132.     Aronstam, R.S., K. Hoey and J.E. Freije, Physician participation in clinical research at Guthrie Health, Guthrie J.  72: 66-71, 2003.

133.     Aronstam, R.S. and P. Patil, Receptors on Autonomic Neurons and Neuroeffector Cells: Muscarinic Receptors. acetylcholine receptors, In: Encyclopedia of Neuroscience (G. Adelman and B Smith, eds.), CD-ROM, Elsevier Press, Amsterdam, 2008 (Fourth Edition).

134.     Shi, R.,C.-C. Huang, R.S. Aronstam, N. Ercal, A. Martin and Y-W. Huang, N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes, BMC Pharmacology 9:7, 2009. doi:10.1186/1471-2210-9-7; http://www.biomedcentral.com/1471-2210/9/7

135.      Huang, C.-C., R.S. Aronstam, D.-R. Chen and Y.-W. Huang, Oxidative stress, calcium homeostasis and altered gene expression in human lung epithelial cells exposed to ZnO nanoparticles, Toxicology In Vitro 24:45-55, 2009; doi:10.1016/j.tiv.2009.09.007

136.     H.-J. Wang, T.-H. Tang, A.C. Growcock, J. O’Hara, , A. Martin, Y.-W. Huang and R.S. Aronstam, ZnO Nanoparticle Inhibition of Muscarinic Receptor Ligand Binding and Activation of Store-operated calcium entry, Toxicology In Vitro 24:1953-1961, 2010.

137.      Liu, B.R., J.-F. Li, S.-W. Lu, H.-J. Lee Y.-W. Huang, K. B. Shannon and R.S. Aronstam, Cellular internalization of quantum dots noncovalently conjugated with arginine-rich cell-penetrating peptides, J. Nanosci. Nanotech. 10:1-10, 2010.

138.     Huang, Y-W, C.-H. Wu and R.S. Aronstam, Toxicity of transition metal oxide nanoparticles: Recent Insights from In Vitro Studies, Materials 3(10) 4842-4859, 2010 doi:10.3390/ma3104842, 2010.

139.   Liu, B.R., Winiarz, J.G., Moon J.-S, Lo, S.-Y., Huang, Y.-W., Aronstam, R.S., and Lee, H.-J., Synthesis, characterization and applications of carboxylated and polyethylene-glycolated bifunctionalized InP/ZnS quantum dots in cellular internalization by cell-penetrating peptides, Colloids and Surfaces B: Biointerfaces 111C:162-170, doi: 10.1016/j.colsurfb.2013.05.038, 2013.

141. Liu, B.R., S.-Y. Lo, C.-C. Liu, C.-L. Chyan, Y.-W. Huang, R.S. Aronstam and H.-Jung Lee, Intracellular Delivery of Nanoparticles and DNAs by IR9 Cell-penetrating Peptides,  PLOS OneMay 28;8(5):e64205. doi: 10.1371/journal.pone.0064205, 2013.

141.   Chusuei, C.C., C.-H. Wu, S. Mallararapu, J.G. Winnarz, J.-S. Moon, R.S. Aronstam and Y.-W. Huang, Cytotoxicity in the age of nano: cell toxicity reflects certain physiochemical properties of fourth period of metal oxide nanoparticles, Chemico-Biological Interactions, 205(2) 319-326, 2013.

142.   Liu, B.R., S.-Y. Lo, Y.-W. Huang, R.S. Aronstam and H.-Jung Lee, Intracellular Delivery of Nanoparticles and DNAs by IR9 Cell-penetrating Peptides,  PLOS One, May 28;8(5):e64205. doi: 10.1371/journal.pone.0064205, 2013.

143. Liu, B.R., S.-Y. Lo, C.-C. Liu, C.-L. Chyan, Y.-W. Huang, R.S. Aronstam and H.-Jung Lee, Endocytic Trafficking of Nanoparticles Delivered by Cell-penetrating Peptides Comprised of Nona-arginine and a Penetration Accelerating Sequence, PLOS One, June 26 8(6):e67100. DOI:10.1371/journal.pone.0067100, 2013.

144.   Wang, H.-J, , A.G. Martin, P.-K.Chao, R.A. Reichard, A.L. Martin,Y.-W. Huang, M.-H. Chan and R.S. Aronstam, Honokiol blocks store operated calcium entry in CHO cells expressing the M3 muscarinic receptor, DOI: 10.1186/1423-0127-20-11, J. Biomed. Sciences, 20:11, doi: 10.1186/1423-0127-20-11, 2013.

145.   Tang, T.-H., C.-T Chang, H.-J. Wang, J. Erickson, R.A. Reichard, A.G. Martin, E.C. Shannon, Y.-W. Huang, and R.S. Aronstam, Oxidative stress disruption of receptor-mediated calcium signaling mechanisms, J. Biomed. Sciences, 20(1):48. DOI:10.1186/1423-0127-20-48, 2013.

146.    Chang, M., Y.-W. Huang, R.S. Aronstam and H.-J. Lee, Cellular delivery of noncovalently-associated macromolecules by cell penetrating peptides, Curr. Pharmaceut. Biotechnol. 15: 267-275, 2014.

147.    Huang, Y.-W., H.-J. Lee, L.M. Tolliver and R.S. Aronstam, Delivery of nucleic acids and nanomaterials by cell-penetrating peptides: Opportunities and challenges, BioMed Research International, vol. 2015, Article ID 834079, 16 pages, 2015. doi:10.1155/2015/834079, 2015.

148.   Liu, B.R., H.-H. Chen, M.-H. Chan, Y.-W. Huang, R.S. Aronstam, and H.-J. Lee. Three arginine-rich cell-penetrating peptides facilitate cellular internalization of red-emitting quantum dots. J. Nanosci. Nanotechnol. 15(3):2067-2078, 2015.

149.   Liu, B.R., Y.-W. Huang, R.S. Aronstam, and H.-J. Lee Comparative Mechanisms of Protein Transduction Mediated by Cell-Penetrating Peptides in Prokaryotes, J. Membrane Biol., 1-14, 2/6/15, 2015.



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