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Welcome to Organic and Medicinal Chemistry Research laboratory

Dr. Sandeep Chaudhary was born and raised up in the defence environment family (Birthplace: Jodhpur). He did his M.Sc  in Chemistry from Deen Dayal Upadhyay Gorakhpur University (DDUGU), Gorakhpur, UP. After qualifying several competitive exams such as NET, GATE, ASRB etc.; He did his Ph.d in Organic and Medicinal Chemistry from CSIR-Central Drug Research Institute, Lucknow and Jawaharlal Nehru University, New Delhi from 2002-2007 with Prof. Dr. Chandan Singh [Scientist G (Retd.), Director Grade Scientist]. He then moved to USA and worked as Postdoctoral fellow at The City University of New York, New York, USA from 2008-2010 with Prof. Wayne W. Harding [Associate Professor, CUNY - Hunter College]. After that, he got JSPS Postdoctoral fellowship from Japan Society for the Promotion of Science (JSPS), Japan at Institute of Microbial Chemistry, Microbial Chemistry Research Foundation, Tokyo, Japan from 2010-2012 with Prof. Dr. Masakatsu Shibasaki [Director, IMC - MCRF, Tokyo; Emeritus Professor, The University of Tokyo & Hokkaido University].
Dr. Sandeep Chaudhary is currently working as an Assistant Professor in the Department of Chemistry, Malaviya National Institute of Technology Jaipur (MNIT Jaipur), Rajasthan, India since 2012. Since 2013, he also holds the Adjunct Faculty position at Materials Research Centre, MNIT Jaipur.
His research focuses on the development of new reaction methodologies and its application to the synthesis of biologically active natural products/Drugs/Therapeutics. We are also interested in carrying out mechanism/target/structure-based drug discovery, lead generation and lead optimization via design, synthesis and SAR study of new bioactive molecules, particularly in the field of novel antimalarials, antitubercular, anti-nociceptive, anti-parasitic, anticancer, anti-influenza and psycho-active (CNS) agents. We also try to explore the design and development of new metal-ligand catalyst systems and their investigations in Carbon-carbon bond forming reactions and direct arylation reactions with special emphasis by the use of cheaper transition metals. Investigation of cross coupling, hydroarylations, and Cyclization as well as addition reactions via development of metal-ligand catalytic systems will also be pursued.  Apart from that, but not the least, we are also concern with the design and development of new metallo-catalyst and organo-catalysts as well as the development of new direct catalytic asymmetric C-C bond-forming transformations.

Research Areas

Medicinal chemistry, drug discovery & process development: Mechanism/target/structure-based drug discovery, lead generation and lead optimization; Design, Synthesis and SAR study of new bioactive molecules, particularly in the field of novel antimalarials, antitubercular, anticancer, anti-influenza and psychoactive (CNS) agents.

Nano biotechnology: Development of nano carrier based anticancer drug delivery

Development of catalytic asymmetric reactions / New Synthetic Methodologies.

Asymmetric catalysis / Synthesis: Design and development of new metallo-catalyst and organo-catalysts, development of direct catalytic asymmetric C-C bond-forming transformations.

Total synthesis of biologically active Natural Products/Drugs/Therapeutics.

Transition Metal - catalyzed C―C & CN bond formation via C―H bond activation: Exploration with special emphasis by the use of cheaper transition metals; design and development of new metal-ligand catalyst systems and their investigations in direct arylation reactions. Investigation of cross coupling, hydroarylations, and Cyclization as well as addition reactions via development of metal-ligand catalytic systems will also be pursued.

Green chemistry: Application of microwave-assisted/ ultrasound-assisted organic transformations; Explorations of organic reactions either under solvent-free conditions or using cheap innocuous alternate reaction media such as water and ionic liquids.

Nano biotechnology: Development of nano carrier based anticancer drug delivery

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