Recent Updates

  • Press Release on TIMES 12/06/2016: An article, "Transient Induced Molecular Electronic Spectroscopy (TIMES): New technique to study how proteins and ligands interact", is reported by University of California San Diego news and ...
    Posted Dec 6, 2016, 2:36 PM by Tony Yen
  • Lo Group Member Wins Award 11/02/2016: PhD student Yu-Jui (Roger) Chiu received the best student paper award from 16th International IEEE Conference on Bioinformatics & Bioengineering (BIBE-16).
    Posted Feb 2, 2017, 10:35 AM by Roger Chiu
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We are the Lo Research Group in the UC San Diego Jacobs School of Engineering. Areas of research within the lab include lab on a chip devices and high sensitivity photodetection. We are looking to apply electrical engineering to medicine and photodetection.

Lab on a Chip Devices

Lab-on-a-chip devices are small, often disposable chips that incorporate the full functionality of an assay or device. These chips are generally meant to be inexpensive and mass-produced. Their functionality is frequently derived from a multi-disciplinary approach to design and fabrication, involving microfabrication, microfluidics, photonics, and electronics. Our group is working on developing key enabling technologies for lab-on-a-chip devices, including microfluidic flow control, acoustics-based flow/sample control, and optical system development through a combination of simulations and experiments. We have chosen polymer-based flow cytometry chips as our test system for its system complexity, rapid prototyping ability, and widespread utility.

High Sensitivity Photodetection

The area of high sensitivity photo detection at different optical wavelengths has a myriad of applications and far-reaching consequences including free space, fiber optic, and quantum communications, 3D imaging, medical imaging, remote sensing, DNA sequencing and biosensing, quantum cryptography, and many more. Our main focus is to achieve single photon sensitivity, the ultimate sensitivity for any detectors, in a large array format. Such performance represents the quantum limit of light detection and will have tremendous impact on all technical fields using photons to encode or transmit information. Our work is particularly focused on semiconductor devices, also with interests in biological and bioinspired systems related to human vision. Specific approaches include single photon avalanche detectors (SPADs), nanowire detectors, exciton detectors, and detectors using the newly discovered cycling excitation process (CEP) as an extremely efficient and low noise signal amplification mechanism.