The Cassimeris lab group is
interested in how animal cells proliferate - how cells increase in numbers
through growth and division. Cell proliferation underlies processes such as
development, where a single fertilized egg grows and divides into the trillions
of cells of the adult, as well as the uncontrolled growth and division of
Unraveling the mechanisms responsible for cell growth,
division and survival will allow biologists to control cell proliferation in
time or space, for example blocking cancer cell proliferation or controlling
stem cell growth. Our work focuses on the cell's internal skeleton, built of
polymers that assemble and disassemble every minute. These polymers (microtubules) are responsible for separating the genome into each daughter cell at each cell division and are the target of some of the most successful anti-cancer drugs.
Dept. of Biological Sciences
111 Research Dr.
Bethlehem, PA 18015