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The Cassimeris lab group is interested in how animal cells proliferate - how cells increase in numbers through growth and division. Cell proliferation underlies processes such as development, where a single fertilized egg grows and divides into the trillions of cells of the adult, as well as the uncontrolled growth and division of cancer cells. Unraveling the mechanisms responsible for cell growth, division and survival will allow biologists to control cell proliferation in time or space, for example blocking cancer cell proliferation or controlling stem cell growth. Our work focuses on the cell's internal skeleton, built of polymers that assemble and disassemble every minute. These polymers (microtubules) are responsible for separating the genome into each daughter cell at each cell division and are the target of some of the most successful anti-cancer drugs.






Mailing Address

Dept. of Biological Sciences

111 Research Dr.
Lehigh University
Bethlehem, PA 18015
USA