Alexander House, 22 N. College Ave., Oxford, was added to the National Register of Historic Places in 1987. The web site of the Ohio Historic Preservation Office of the Ohio Historical Society says the house "was associated with two important local physicians and community leaders, Dr. Herschel Hinkley and Dr. William Alexander. In the days before hospitals and clinics, the doctor's office was a haven for the small town's ill and injured." Both doctors also were associated with Miami University. "They represent therefore, an earlier example of the 'town-gown' cooperation that has long been a constant issue in this and other small Ohio college communities.
"Architecturally the house is a well-preserved example of an I-house, with transitional Greek Revival-Italianate styling. While this styling is not uncommon in this area, it is the two-story side portico which clearly distinguishes this house from others in Oxford.
"In 1867 inlot 176 was acquired by John M. Shera, a local farmer, who built a traditional Greek Revival-Italianate style house on it in 1869. In 1888 Dr. Herschel D. Hinkley and his wife bought the house from the Shera family. In 1895 Dr. Hinkley sold the house and his medical practice to Dr. William S. Alexander. Dr. Alexander lived in and used the house for his practice until his death in 1917. In 1954 the descendants of Dr. Alexander divided the interior of the house into four apartments.
"Dr. Herschel D. Hinkley was a respected member of the community in Oxford before taking up residence at 22 N. College Avenue. While living there, Dr. Hinkley was appointed to a nine-year term on the Miami University Board of Trustees. He was offered the chair of surgery at Cincinnati College of Medicine in 1894, which he accepted. That same year he was awarded an honorary degree by Miami University.
"Dr. William S. Alexander . . . became active in the Oxford community. In 1905 he was elected to the Oxford Village Council where he served for four consecutive two-year terms under two administrations. In the teens, Dr. Alexander was appointed by the Miami University Board of Trustees to serve as physician to men. The house remained in the Alexander family until it was sold Feb. 5, 1985."
The Ohio Historic Preservation Office says "the basic architecture of the house is typical of the mid-to-late 19th century residential properties in southwest Ohio, a five-bay I-house. The Alexander House is a particularly well preserved example of this period in Oxford where the overwhelming need for temporary rental housing frequently resulted in major remodeling of residences of this era. By far the most distinguished element of the architecture is the two-story side portico constructed about the turn-of-the-century. This feature is found nowhere else in the city."
In recent years, the Alexander House has been a restaurant and bed and breakfast.