Collaborators‎ > ‎

Brandon Guthrie, PhD, Acting Instructor

Dr. Guthrie completed his PhD from the University of Washington in 2009, with dissertation research on “Transmission and Potential Resistance Among HIV-1-Discordant Couples.” Dr. Guthrie is currently an Acting Instructor working on the NIH/Fogarty funded study Modeling Generalizability of Intervention Trials in HIV-1-discordant Couples, which is assessing the distribution of characteristics relevant to HIV transmission in HIV-discordant couples in the general population in Kenya. This information will enable the construction of mathematical models for population effectiveness of HIV prevention interventions. Dr. Guthrie also works on the Protective Cellular Immune Responses in HIV-1 Discordant Couples (CAT) study. Dr. Guthrie works both in Seattle and Kenya, spending approximately 3 months a year in Kenya. His primary research focuses on HIV-1-discordant couples and their relevance to ongoing HIV epidemics. He is broadly interested in modeling, monitoring, and evaluating effectiveness to optimize implementation of public health interventions. Dr. Guthrie is a lecturer in the “Principles of HIV Research” taught in Nairobi, and is the co-director and lecturer in the Epidemiology/Biostatistics module of a fellowship program that trains students in HIV program management, health economics, and health informatics, in collaboration with the University of Nairobi.


Representative Publications:


Bosire R, Guthrie BL, Lohman-Payne B, et al. Longitudinal comparison of chemokines in breast milk early postpartum among HIV-1-infected and uninfected Kenyan women. Breastfeeding Medicine. Sep 2007;2(3):129-138. [PMID: 17903098]


Guthrie BL, de Bruyn G, Farquhar C. HIV-1-discordant couples in sub-Saharan Africa: explanations and implications for high rates of discordancy. Curr HIV Res. 2007;5(4):419-432. [PMID: 17627505]


Guthrie BL, Kiarie JN, Morrison S, John-Stewart GC, Kinuthia J,Whittington WL, Farquhar C. 2009. Sexually Transmitted Infections Among HIV-1 Discordant Couples. PLoS ONE, 4(12): e8276. DOI:10.1371. [PMCID: PMC2788224]


Guthrie BL, Choi RY, Bosire R, Kiarie JN, Mackelprang RD, Gatuguta A, John-Stewart GC, Farquhar C. 2010. Predicting Pregnancy in HIV-1-Discordant Couples. AIDS and Behavior, DOI: 10.1007/s10461-010-9716-x. (In Press)