Trayambak Basak and Ajay Bhat, Research Scholars, CSIR-IGIB..... Proteomics has great potential in discovering potential biomarkers for several diseases that could aid in diagnosis and management of diseases. Blood plasma is usually used as it remains in contact with nearly all cells of the organism and is also easily accessible. After immuno-depletion of the abundant proteins, identification of low abundant proteins that are differentially expressed in diseased conditions compared to healthy controls is achieved through various quantitative techniques. | Basak T, Bhat A, Malakar D, Pillai M, Sengupta S In-depth comparative proteomic analysis of yeast proteome using iTRAQ and SWATH based MS. Mol. Biosystems, 2015, 11(8), 2135-43. (Cover Page article) |
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