Wellstein Lab


About

Dr. Wellstein trained as an MD & PhD (Pharmacology) in Germany and then on a sabbatical at NCI/NIH to study growth factor signaling in breast cancer in Marc E Lippman’s lab. He was then recruited to the faculty of Georgetown University in the Departments of Pharmacology and Oncology, where he is a tenured Professor. His lab discovered that the receptor for the growth factor pleiotrophin is ALK (anaplastic lymphoma kinase) and defined the role of secreted binding proteins for FGF (FGFBPs) in cancer, physiology and development. Dr. Wellstein’s work is focused on tumor / stromal interaction with a particular emphasis on the activity of FGFs and the pleiotrophin/ALK signaling pathways. His major interest is in mechanisms of cancer invasion and metastasis. His laboratory studies cellular, molecular and biochemical signal transduction mechanisms in vitro as well as in tumors, transgenic and knockout animal models and clinical samples. Published >170 papers.